CA1130439A - Ultrasonic transducer array - Google Patents

Ultrasonic transducer array

Info

Publication number
CA1130439A
CA1130439A CA325,790A CA325790A CA1130439A CA 1130439 A CA1130439 A CA 1130439A CA 325790 A CA325790 A CA 325790A CA 1130439 A CA1130439 A CA 1130439A
Authority
CA
Canada
Prior art keywords
elements
transducer
array
width
transducer array
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA325,790A
Other languages
French (fr)
Inventor
David A. Carpenter
George Kossoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commonwealth of Australia
Original Assignee
Commonwealth of Australia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commonwealth of Australia filed Critical Commonwealth of Australia
Application granted granted Critical
Publication of CA1130439A publication Critical patent/CA1130439A/en
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22Details, e.g. general constructional or apparatus details
    • G01N29/26Arrangements for orientation or scanning by relative movement of the head and the sensor
    • G01N29/262Arrangements for orientation or scanning by relative movement of the head and the sensor by electronic orientation or focusing, e.g. with phased arrays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/13Tomography
    • A61B8/14Echo-tomography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B06GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
    • B06BMETHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
    • B06B1/00Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
    • B06B1/02Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
    • B06B1/06Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
    • B06B1/0607Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using multiple elements
    • B06B1/0622Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using multiple elements on one surface
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/04Analysing solids
    • G01N29/06Visualisation of the interior, e.g. acoustic microscopy
    • G01N29/0609Display arrangements, e.g. colour displays

Abstract

ABSTRACT OF THE DISCLOSURE
An apparatus for the ultrasonic examination of an object, comprises a transducer array comprising a plurality of adjacent transducer elements for directing pulses of ultrasonic energy along a beam into the object, characterised in that the width of each of the transducer elements in the direction transverse to the longitudinal direction of the element varies along the length of the element.

Description

~ ~ 3~ 9 FIELD OF T~E INVENTION
This invention relates to ultrasonic transducers used in ultrasonic ecl~oscopy ol o~jects and in particular to ultrasonic transducer arrdys for use at megahertz ultra-sonic frequellcies in ecilosco~y techniques designed toproduce useful informatioli concerning examined objects (typically, but not exclusively, concerning the more effec-tive acquisition of data in medical diagnosis)-_CKGROUI~D TO THE INVENTION
Ultrasonic echoscopy provides information about an examined object which may be displayed in the form of an ultrasonic echogram. Such an echo-gram consists of a display of acoustic impedance discontinuities or reflecting surfaces in the object.
It is obtained by directing a short pulse of ultra-sonic energy, typically in the 1-30 MHz frequency ange, along a line called the beam axis into the examined object where any acoustic impedance dis-continuities in the object reflect and return some of the energy along the same beam axis in the form of an echo. This echo is received, converted into an elec-tric signal and displayed as an echogram on a cathode ray oscilloscope, a film, a chart or the like.
The echogram may constitute either a one dimensional or a two dimensional representation and in both cases the information is contained in the position and magnitude of the echo displayed. In a one dimensional display, the position along a base line is used to indicate the distance to the reflec-ting surface whilst the magnitude of the echo isdisplayed, for example, as a deflection of the base line or as an intensity change. In a two dimensional display, the position along a base line is used to indicate the distance to the reflecting surface as in a one dimensional display, and the direction of the base line is used to represent the direction of ~p~. ..
-2- ~3~4~

propagatiOn of the acoustic energy which is the beam axis. The two dimensional display is obtained by changing this direction of propagation of the acoustic energy and by instituting a similar but not necessarily identical movement of the base line of the display.
The magnitude of the echo is displayed as for a one dimensional display; for example, as a deflection of the base line or as an intensity change.
The technique of ultrasonic echoscopy is used in medical diagnosis to obtain information about the anatomy of patients. The application of this technique is now widely investigated and is described, for example, by D.E. Robinson in "Proceedinas of the Institution of Radio and ~lectronics Engineers Australia", Vol. 31 No. 11, pages 385-392, l~ovember 1970, in his paper entitled:
"The Application of Ultrasound in Medical Diagnosis". As pointed out in this article, ultrasonic echoscopy may be used to produce displays resembling anatomical cross-sections wh'ch have proved clinically useful when the desired information concerns physical dimensions, shapes of organs or structures or the like. Ultrasonic echography has prcved of particular value as a diagnostic aid in the abdomen and pregnant uterus, eye, breast, brain, lung, kidney, liver and heart, these being areas of soft tissue with little bone and air. In general, the technique is considered to complement other techniques to provide a more com-plete picture of the patients condition, however particularly in pregnancies, ultrasonic echoscopy may be useful in place of X-rays where the latter may not give sufficient information or may be dangerous. In medical use, a pulse of ultrasonic ener~y is trans-mitted into a patient in a known direction and echoes are received from reflecting surfaces within the body.
The time delay between a transmitted pulse and the . ~

~,~3ir~

received echo depends on the distance from the transmitter to the reflecting surface and the distance information so obtained may be displayed in a suitable way for interpretation and clinical use as a one dimensional range reading or as a two dimensional cross section as previously described.
This known system has sufferred from a dis-advantage due to the time required to obtain a cross-sectional picture. The cross-sectional picture is made up of a multiplicity of lines of information corres-ponding to each beam axis position at which a pulse was transmitted and echoes received. The time required to obtain each line of information is fixed by the depth of the tissues of interest and the velocity of propagation of sound in the tissues to be examined.
For a particular area of interest neither of these parameters is under the control of the operator and they form a basic limitation on the time required to obtain an echogram.
In U.S. Patent 3,789,833 to Bom, there is disclosed the formation of an array of transducer elements arranged in a line, each providing a separate ultrasonic line of sight. Each array element is pulsed in turn, returned echoes are received and dis-played on a screen and then another array element is pulsed. One prime limitation of the system disclosed by Bom is that the line spacing fixes the size of the transducer elements and the resulting ultrasonic resolution. U.S. Patent 3,881,466 to Wilcox discloses the use of a plurality of transducer elements to form each ultrasonic beam, thus breaking the link between line spacing and resolution. In addition, U.S.
Patents 3,166,731 to Joy and 3,086,195 to Halliday disclose the application of time delays to signals associated with the various elements of a transducer ~3~ 9 element array in forming the ultrasonic beam, to cause an electronic steering and focusing action within the plane of scan.
It will thus be apparent that ultrasonic transducers consisting of an array of elements are being used to provide rapid cross sectional imaging, particularly in medical diagnosis. These transducers are usually rectangular piezo-electric ceramic elements sandwiched between two electrodes. The thickness of the element is selected so that the element resonates at the required megahertz ultrasonic frequency (that is, the frequency of the ultrasonic energy to be propogated into the object or medium to be examined). At megahertz fre-quencies, this means that the thickness of the element is approximately equal to half the wavelength. Imaging is obtained by energising either one or a group of elements to provide a single line of sight of ultrasonic information and a cross sectional image may be built up by sequentially energising the elements as described above. Because of considerations imposed by the number of lines used to form the image and lateral resolution requirements, the width of the elements forming the array typically ranges from half the wavelength to two wavelengths, whilst the length dimension of the rectangular elements is usually greater than ten wavelengths.
A common method of constructing such transducer arrays is to use a relatively large rectangular ceramic transducer, corresponding in size to the transducer array, and to divide this transducer to form the indi-vidual transducer elements of the array.
One method of construction includes the scribingof fine lines on one or both of the surfaces of the relatively large transducer, to cut through one or both of the electrodes to provide electric insulation between individual elements of the array. This method of array A

-5_ 1~.3'~

construction results in an array with high sensitivity, for the unenergised transducer material lying alongside an activated array element damps and restrains the trans-fer of energy from the thickness mode (in which the element is energised) into other modes which could be forced into resonance due to the mechanical coupling that exists within the massive piezo-electric ceramic forming the elements of the array. Unfortunately, the presence of this material allows a small transfer of energy between adjacent elements, which results in a significant cross talk between elements.
In an alternative construction, the relatively massive piezo-electric ceramic transducer is cut through completely to form a series of rectangular elements.
This method of construction reduces the degree of cross talk between elements since, due to the complete cut, there is no direct mechanical coupling between the adjacent transducer elements. However, as the thickness and the width of the transducer elements are now comparable, there is significant transfer or coupling of energy between adjacent elements due to resonance effects.
Consequently, the sensitivity of the element, and thus of the array, is reduced.
SUMMARY OF THE INVENTION
_ _ .
Both cross talk and loss of sensitivity are overcome by the present invention, which provides a transducer array - typically formed by cutting a relatively large piezo-electric transducer - in which each element of the array is isolated from its neighbour, and width-mode resonance coupling of adjacent elements is eliminated, or at least markedly reduced, by varying the width of the element along its length.
According to the present invention, there is provided, for the megahertz frequency ultrasonic examination of an object, a transducer array comprising a plurality of closely spaced, generally elongate transducer elements ~3~

arranged for directing pulses of ultrasonic energy into the said object, each element comprising a piezo-electric ceramic material sandwiched between a pair of planar and parallel electrodes, charaterized in that the width of each of said transducer elements in the direction transverse its longitudinal direction is non-uniform along the length of the element.
Preferably, the transducer array is a Iinear transducer array.
In one preferred embodiment of the present invention, the width of each transducer element in the array varies uniformly along the length of the element from one end thereof to the opposite end.
In a particularly preferred arrangement of such an array, the plurality of transducer elements comprises a first series of elements in which the width of each element increases uniformly along the length of the element from one end thereof to the opposite end in a given direction, and a second series of transducer elements, the individual elements of which are interposed between the elements of the first series, in which the width of each element decreases uniformly along the length of the element from one end thereof to the opposite end in that given direction. In these embodiments of the invention, each of the individual transducer elements of the array may be in the form of a trapezium, with each trapezoidal element being inverted with respect to its immediately adjacent elements.
In further embodiments of the invention, the width of each transducer element may increase and then decrease again, or decrease and then increase again, along the length of the element from one end thereof to the opposite end. In a particularly preferred aspect of this embodiment, the plurality of transducer elements comprises a first series of transducer elements in 1~l3~

which the width of each element decreases and then increases again along the length of the element from one end thereof to the opposite end in a given direction, and a second series of transducer elements, the elements of which are interposed between the elements of the first series, in which the width of each element increases and then decreases again along the length of the element from one end thereof to the opposite end in the given direction.
As the transducer elements of the array of this invention are independent, they are preferably mechanically supported by adhesion to a base, for example, a base of an epoxy resin such as "Araldite". Additionally, or alter-natively, the individual elements may be bonded by a bonding material between adjacent elements of the array.
Such a bonding material may, for example, be an epoxy resin such as '`Araldite".
It will be appreciated that the transducer array of the present invention may be used in place of known arrays of rectangular elements in all types of multi-2D element transducers. In use of the transducer array inapparatus for the megahertz ultrasonic examination of an object, means are provided for energising the elements of the array to direct pulses of ultrasonic energy along a beam into this object. This means may include means for energising the elements of the array in phased relation for focusing and for scanning the beam by sequentially energising the elements of the array. In this manner, control of the time of energising the elements may be used to steer and focus the ultrasonic beam. Further features of the present invention will be apparent from the following description of the embodiments of the invention which are illustrated in the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGS
Figure 1 illustrates, in perspective view, a linear array of trapezoidally shaped ultrasonic transducer elements.

~3~ 3~

Figure 2 illustrates, in perspective view, a linear array of ultrasonic elements, each of which has a width which varies non-linearly with its length.
Figure 3 is a schematic side elevation of a modified form of the array of Figure 1.
DETAILED DESCRIPTION OF EMBODlMENTS
Referring firstly to Figure 1, there is shown a linear array 10 of transducer elements which have been formed from a single piezo-electric ceramic transducer.
Each individual transducer element El, E2, .., E8, has the shape of a trapezium. Whilst 8 elements are shown as making up the array 10, it will of course be appreciated that the actual number of the elements in an array will be the number required for the apparatus in which the array is to be used. Each of the elements El, E2, ...
E8, includes a pair of metal electrodes 11 and 12 which will typically be of silver or aluminium. The piezo-electric material 13 of the elements is typically barium titanate ceramic. The base 14 of the array, to which each 20 of the elements El, E2, , E8, is bonded to provide mechanical support for the transducer array, may be an epoxy resin.
As shown in Figure 3, the interstitial spaces of the elements of the array may be filled with an acoustically non-coupling material 15. Such a material may be an epoxy resin, for the inclusion of an epoxy resin between individual elements of the array effectively bonds them, for strength, without coupling the elements acoustically.
It will be understood, that if each of the elements El, E2, .., E8, is energised simultaneously, an ultrasonic beam at right angles to the free surface of the array will be produced. The beam may, however, be steered electronically by sequentially activating the elements El, E2, .., E8. Additionally, or 9- ~3 ~

alternatively, the array 10 may be focused by energising simultaneously the first and last elements (El and E8) and then energising the next two elements tE2 and E7) and so on until finally the centre element or elements have been energised. Such means for energising elements of the array are well known in the prior art and for this reason are not shown in the accompanying drawings.
Referring now to Figure 2 of the drawings, it will be seen that the shapes of the elements el, e2, .., e8 thereof differ from the shapes of the elements El, E2, .., E8, of Figure 1. However, apart from these different shapes, the array 20 is identical in structure to the array 10 of Figure 1.
In Figures 1 and 2, the letter A has been used to indicate the thickness resonance mode of each element of the array, whilst the letter B has been used to indicate the width resonance mode of the elements.
It has been found that the use of an array of transducer elements, designed to operate at megahertz frequencies, in which each element has a width which varies along its length is effective to dampen the width resonance mode of the elements, and thus substan-tially reduce the degree of transfer of energy from the thickness mode of ultrasonic vibration to the width mode of resonance, hence giving high sensitivity for the array.
Moreover, the use of a complete cut or separation between the elements of the array eliminates the mechanical coupling between elements and reduces the degree of cross talk between elements.
It will be appreciated that the particular embodiments referred to above are given by way of exemplification of the present invention only, and many modifications and variations may be made thereto without departing from the spirit and scope of the present invention, as defined in the appended claims.

.~
A

Claims (9)

We claim
1. A transducer array for use in the megahertz ultrasonic examination of an object, comprising a plurality of closely spaced, generally elongate trans-ducer elements arranged for directing pulses of ultrasonic energy into the said object, each element comprising a piezo-electric ceramic material sandwiched between a pair of planar and parallel electrodes, characterized in that the width of each of said transducer elements in the direction transverse its longitudinal direction is non-uniform along the length of the element.
2. A transducer array as defined in claim 1, further characterized in that said transducer array is a linear transducer array.
3. A transducer array as defined in claim 1 or claim 2, further characterized in that the width of each transducer element varies uniformly along the length of the element from one end thereof to its other end.
4. A transducer array as defined in claim 1 or claim 2, wherein said plurality of transducer elements comprises a first series of transducer elements in which the width of each element increases uniformly along the length of the element from one end thereof to its other end in a given direction, and a second series of trans-ducer elements, the elements of which are interposed between the elements of said first series, in which the width of each element decreases constantly along the length of the element from one end thereof to its other end in said given direction.
5. A transducer array as claimed in claim 1 or claim 2, wherein said plurality of transducer elements comprises a first series of transducer elements in which the width of each element decreases and then increases again along the length of said element from one end thereof to its other end in a given direction, and a second series of transducer elements, the elements of which are interposed between the elements of said first series, in which the width of each element increases and then decreases again along the length of the said element from one end thereof to its other end in said given direction.
6. A transducer array as defined in claim 1, wherein said plurality of transducer elements are supported on a base.
7. A transducer array as defined in claim 1, further including a bonding material in the spaces between the transducer elements.
8. Apparatus for ultrasonic examination of an object at megahertz frequencies, including a transducer array as defined in claim 1, and means for energising the elements of the said array to direct pulses of ultrasonic energy into the said object.
9. Apparatus as claimed in claim 8, further including means for energising the elements of the said array in phased relation for focusing and scanning said beam.
CA325,790A 1978-04-19 1979-04-12 Ultrasonic transducer array Expired CA1130439A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU410978 1978-04-19
AUPD4109/78 1978-04-19

Publications (1)

Publication Number Publication Date
CA1130439A true CA1130439A (en) 1982-08-24

Family

ID=3694568

Family Applications (1)

Application Number Title Priority Date Filing Date
CA325,790A Expired CA1130439A (en) 1978-04-19 1979-04-12 Ultrasonic transducer array

Country Status (8)

Country Link
US (1) US4254661A (en)
JP (1) JPS555678A (en)
AT (1) AT368865B (en)
AU (1) AU529113B2 (en)
CA (1) CA1130439A (en)
DE (1) DE2915761A1 (en)
FR (1) FR2423207A1 (en)
GB (1) GB2019565B (en)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2929541A1 (en) * 1979-07-20 1981-02-05 Siemens Ag ULTRASONIC CONVERTER ARRANGEMENT
DE3122036C2 (en) * 1981-05-29 1983-12-08 Mannesmann AG, 4000 Düsseldorf Probe holder for single and multiple probes
JPS59225045A (en) * 1983-06-07 1984-12-18 松下電器産業株式会社 Ultrasonic probe
JPS6193951A (en) * 1983-09-13 1986-05-12 Nippon Dempa Kogyo Co Ltd Ultrasonic probe and its production
US4549533A (en) * 1984-01-30 1985-10-29 University Of Illinois Apparatus and method for generating and directing ultrasound
US4582065A (en) * 1984-06-28 1986-04-15 Picker International, Inc. Ultrasonic step scanning utilizing unequally spaced curvilinear transducer array
DE3720574A1 (en) * 1987-06-22 1989-01-05 Deutsch Pruef Messgeraete Ultrasonic multiple probe
NL8801776A (en) * 1988-07-13 1990-02-01 Optische Ind De Oude Delft Nv ULTRASONIC TRANSDUCER INCLUDING AT LEAST ONE ROW OF ULTRASONIC ELEMENTS.
JPH09138224A (en) * 1995-11-14 1997-05-27 Mitsubishi Electric Corp Array probe
JP3282472B2 (en) * 1995-11-27 2002-05-13 三菱電機株式会社 Composite probe device
US6725721B2 (en) * 2001-10-22 2004-04-27 Magnetic Analysis Corporation Ultrasonic multi-element transducers and methods for testing
JP4703382B2 (en) * 2005-02-14 2011-06-15 富士フイルム株式会社 Structure of transducer array, manufacturing method thereof, and ultrasonic probe
US7652410B2 (en) * 2006-08-01 2010-01-26 Insightec Ltd Ultrasound transducer with non-uniform elements
US7757559B2 (en) * 2007-05-25 2010-07-20 Magnetic Analysis Corporation Oblique flaw detection using ultrasonic transducers
CN102333486A (en) * 2009-02-24 2012-01-25 皇家飞利浦电子股份有限公司 Ultrasonic vascular flow sensor with triangular sensor geometry
WO2011024074A2 (en) 2009-08-26 2011-03-03 Insightec Ltd. Asymmetric phased-array ultrasound transducer
GB0916427D0 (en) * 2009-09-21 2009-10-28 Univ Dundee Ultrasound transducer array
EP2489034B1 (en) 2009-10-14 2016-11-30 Insightec Ltd. Mapping ultrasound transducers
US8691145B2 (en) 2009-11-16 2014-04-08 Flodesign Sonics, Inc. Ultrasound and acoustophoresis for water purification
US9852727B2 (en) 2010-04-28 2017-12-26 Insightec, Ltd. Multi-segment ultrasound transducers
US10370635B2 (en) 2012-03-15 2019-08-06 Flodesign Sonics, Inc. Acoustic separation of T cells
US9796956B2 (en) 2013-11-06 2017-10-24 Flodesign Sonics, Inc. Multi-stage acoustophoresis device
US10322949B2 (en) 2012-03-15 2019-06-18 Flodesign Sonics, Inc. Transducer and reflector configurations for an acoustophoretic device
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US9272234B2 (en) 2012-03-15 2016-03-01 Flodesign Sonics, Inc. Separation of multi-component fluid through ultrasonic acoustophoresis
US9783775B2 (en) 2012-03-15 2017-10-10 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
US10953436B2 (en) 2012-03-15 2021-03-23 Flodesign Sonics, Inc. Acoustophoretic device with piezoelectric transducer array
US9752114B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc Bioreactor using acoustic standing waves
US10689609B2 (en) 2012-03-15 2020-06-23 Flodesign Sonics, Inc. Acoustic bioreactor processes
US9745548B2 (en) 2012-03-15 2017-08-29 Flodesign Sonics, Inc. Acoustic perfusion devices
US9567559B2 (en) 2012-03-15 2017-02-14 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
US9752113B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc. Acoustic perfusion devices
US10737953B2 (en) 2012-04-20 2020-08-11 Flodesign Sonics, Inc. Acoustophoretic method for use in bioreactors
EP2813846A3 (en) * 2013-04-02 2015-02-25 Sonotec Ultraschallsensorik Halle GmbH Segmented ultrasonic transducer and gas bubble sensing device comprising the same
US9745569B2 (en) 2013-09-13 2017-08-29 Flodesign Sonics, Inc. System for generating high concentration factors for low cell density suspensions
CA2935960C (en) 2014-01-08 2023-01-10 Bart Lipkens Acoustophoresis device with dual acoustophoretic chamber
US9744483B2 (en) 2014-07-02 2017-08-29 Flodesign Sonics, Inc. Large scale acoustic separation device
US10106770B2 (en) 2015-03-24 2018-10-23 Flodesign Sonics, Inc. Methods and apparatus for particle aggregation using acoustic standing waves
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US10640760B2 (en) 2016-05-03 2020-05-05 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
US11021699B2 (en) 2015-04-29 2021-06-01 FioDesign Sonics, Inc. Separation using angled acoustic waves
CN112044720B (en) 2015-07-09 2023-07-04 弗洛设计声能学公司 Non-planar and asymmetric piezoelectric crystals and reflectors
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
US10710006B2 (en) 2016-04-25 2020-07-14 Flodesign Sonics, Inc. Piezoelectric transducer for generation of an acoustic standing wave
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
JP2020513248A (en) 2016-10-19 2020-05-14 フロデザイン ソニックス, インク.Flodesign Sonics, Inc. Affinity cell extraction by sound
EP3725092A4 (en) 2017-12-14 2021-09-22 FloDesign Sonics, Inc. Acoustic transducer drive and controller

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2961637A (en) * 1955-06-24 1960-11-22 Bendix Corp Underwater transducer having a longitudinally vibratile element
US3111595A (en) * 1959-09-25 1963-11-19 Acoustica Associates Inc Low frequency resonant transducers
US3079584A (en) * 1959-10-23 1963-02-26 Claude C Sims High pressure piezoelectric hydrophone with tungsten backing plate
US3150347A (en) * 1959-11-30 1964-09-22 Hanish Sam Underwater transducer element
US3699507A (en) * 1970-08-05 1972-10-17 Dynamics Corp Massa Div Baffle structure for underwater transducer array
US3992693A (en) * 1972-12-04 1976-11-16 The Bendix Corporation Underwater transducer and projector therefor
US3924259A (en) * 1974-05-15 1975-12-02 Raytheon Co Array of multicellular transducers
US3982144A (en) * 1974-08-23 1976-09-21 The United States Of America As Represented By The Secretary Of The Navy Directional low-frequency ring hydrophone
AT381635B (en) * 1975-09-26 1986-11-10 Leitgeb Norbert Dipl Ing Dr DEVICE FOR EXAMINING OBJECTS AFTER THE REFLECTION PRINCIPLE

Also Published As

Publication number Publication date
ATA289879A (en) 1982-04-15
US4254661A (en) 1981-03-10
GB2019565A (en) 1979-10-31
JPS555678A (en) 1980-01-16
AU4610779A (en) 1979-10-25
AT368865B (en) 1982-11-25
AU529113B2 (en) 1983-05-26
FR2423207B1 (en) 1984-08-17
FR2423207A1 (en) 1979-11-16
DE2915761A1 (en) 1979-10-31
GB2019565B (en) 1982-06-03

Similar Documents

Publication Publication Date Title
CA1130439A (en) Ultrasonic transducer array
US5360007A (en) Ultrasonic apparatus
US3936791A (en) Linear array ultrasonic transducer
US5097709A (en) Ultrasonic imaging system
JP3478874B2 (en) Ultrasonic phased array converter and method of manufacturing the same
US5438998A (en) Broadband phased array transducer design with frequency controlled two dimension capability and methods for manufacture thereof
EP1489972B2 (en) Multiple scan-plane ultrasound imaging of objects
US5415175A (en) Broadband phased array transducer design with frequency controlled two dimension capability and methods for manufacture thereof
US3881164A (en) Cross array ultrasonic transducer
US5743855A (en) Broadband phased array transducer design with frequency controlled two dimension capability and methods for manufacture thereof
US4016751A (en) Ultrasonic beam forming technique
US20040066708A1 (en) Ultrasonic transmitting and receiving apparatus
US4252026A (en) Multiple line of sight ultrasonic apparatus
US4078435A (en) Simultaneous display of compound and simple ultrasound scans
EP1815795B1 (en) Ultrasonographic device
Whittingham et al. Transducers and beam forming
CA1201197A (en) Variable focus transducer
US6160340A (en) Multifrequency ultrasonic transducer for 1.5D imaging
US5976091A (en) Limited diffraction broadband phased array transducer with frequency controlled two dimensional aperture capability
JP2743008B2 (en) Ultrasound diagnostic equipment
JPS6340974Y2 (en)
JPS62227327A (en) Ultrasonic probe
JPH0226189B2 (en)
Foster et al. Cylindrical transducer scatter scanner
JP2964147B2 (en) Ultrasound diagnostic equipment

Legal Events

Date Code Title Description
MKEX Expiry