CA1194752A - Perfusion catheter designed as a double catheter - Google Patents

Perfusion catheter designed as a double catheter

Info

Publication number
CA1194752A
CA1194752A CA000425810A CA425810A CA1194752A CA 1194752 A CA1194752 A CA 1194752A CA 000425810 A CA000425810 A CA 000425810A CA 425810 A CA425810 A CA 425810A CA 1194752 A CA1194752 A CA 1194752A
Authority
CA
Canada
Prior art keywords
catheter
tube
splint
perfusion
shunt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000425810A
Other languages
French (fr)
Inventor
Karl Aigner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of CA1194752A publication Critical patent/CA1194752A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M5/1582—Double lumen needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3613—Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M2025/0037—Multi-lumen catheters with stationary elements characterized by lumina being arranged side-by-side
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/0071—Multiple separate lumens

Abstract

ABSTRACT OF THE DISCLOSURE:

Perfusion catheter, designed as a double catheter, with a splint catheter and a mounted second catheter tube, which is shorter than the splint catheter and which branches off from the latter. At a distance from its back end the splint catheter displays a shunt tube and at a certain dis-tance from the attachment point of the shunt tube at least one opening. A solid rod is inserted into the splint catheter from the back end so as to temporarily close the lateral openings and the shunt.

Description

75 ~

The ob]ect of the invention is a perfusion catheter, to be used particularly for isol~ted perfusion of the liver in intra-arterial chemotherapy.
Catheters have long been used for medical purposes and have a variety of applications.
DE-OS 30 10 341 describes a double catheter, the catheter tubes of which can be shifted in relation to each other and which can be employed for venipuncture in hemodialysis. The mobility of the individual catheters makes it possible, after insertion into a vessel, to space the inlets or outlets located at the tips of the individual catheters in such a way that the blood returned into the vessel does not reach the area from which it was removed.
DE-OS 27 03 087 describes a double capacity catheter for extracorporeal hemodialysis with two separate tubes for the removal and return of blood.
The catheter tubes have a coaxial arrangement. At the end not introduced into the blood vessel there is an attachment element for the outer tube. In intra-arterial chemotherapy, however, the know~ catheters have a restricted use, in particular they cannot be used for the isolated perfusion of certain organs or body parts.
The hematogenic metastasis of tumors, particularly from the gastrointestinal region into the liver, occurs by way of the portal vein. For this reason it is desirable to perform isolated perfusion of the tumerous liver by way of the arteria hepatica and the vena portae.
The objective of the present invention is to create a perfusion catheter whose structural design permits isolated perfusion of the liver, without necessita-ting the interruption of circulation through the vena cava and the vena portae and which permits the isolated with-drawal of blood from the liver during perfusion.

,l'~ .

~, s~

'75'~

Accordingly, the invention is herein broadly claimed as a double perfusion catheter of the type having individual catheter tubes solidly attached to each other, being of different lengths, cross-sections, and tapered front openings and having an attachment running off from the catheter tube with a larger diameter, wherein said double perfusion catheter comprises:
a splint catheter; a catheter tube shorter than said splint catheter and mounted on the wall thereof with the back end of said catheter tube running off from the said wall of the splint catheter; a shunt tube connected at one point on the wall of said catheter and running off laterally at a distance from the back end of the splint catheter; and at least one opening, through the said wall of said splint catheter, located at a distance of from 40 to 60 mm from said connection point of said shunt tube.
The invention catheter has the form of a double capacity catheter or a double catheter. The large capacity portion serves to splint the main vessel, which conducts the blood ~rom the lower extremities and the kidneys to the right chamber of the heart. A second, shorter, mounted catheter tube with a smaller diameter serves to drain the venous liver blood during perfusion;
it branches off in the vicinity of the back end of the splinted catheter and is attached to a heart-lung machine by means of a tube attachment. The splint catheter displays one or two holes at a given point on its side, through which the venous blood of the vena 3G renalis can enter the splint catheter placed in the vena cava during perfusion. At a given distance from the opening(s), which ideally are oval along the longitudinal axis of the catheter, the splint catheter displays a shunt tube for attaching an ultra-filtration filter and a pump, through which blood, flowing from the vena portae , ','5~

(which is clamped as it approaches the liver) during - perfusion, is introduced, by means of a temporary, portocaval shunt, into the splint catheter and thus into the vena cava. This shunt contains a roller pump and an ultra-filtration filter for the partial detoxification of the portal blood. Thus, the splint catheter displays a front opening, a back opening, one or two lateral openings, and a shunt; mounted on the thicker splint catheter tube is a second, shorter catheter tube, which runs off to the side in the immediate area of the shunt. In its front portion the double catheter displays only one tube; in the middle portion it displays two parallel tubes, and at the back end only one tube, with a shunt at a certain distance from the back end. The front end of the splint catheter is tapered to /

~ 3 -; -`

~- '3'~ 5.'~', facilitate its introduction ir,to the blood vessel. The end of the second catheter tube is tapered, so that the catheter has a continuously increasing outer diameter as it is transformed into a double tube. It is of crucial important that this transition is a smooth one and that there be no edges, so as to facilitate the introduction of the double tube portion into the vessel. The tapered end of the second, laterally mounted catheter tube pre-ferably displays one or two laterally positioned openings so as to prevent the formation of a front edge. The cross-section of the double catheter tube is oval or egg-shaped. At the front end the cross-section of the splint catheter tube is preferably cir-cular in shape. The inner diameter of the splint catheter is preferably larger than the inner diameter of the second catheter tube. The second catheter tube r~lns off laterally from the splint catheter at a point near the connection of the shunt tube, preferably immediately at the connection.

At a distance from the end of the second, mounted catheter tube the splint catheter tube displays one or two openings, which may face each other or may be placed diagonally in succession on the side turned away from the second catheter tube. The pre-ferred shape of the openings is oval, with the longitudinal side lying on the longitudinal axis of the splint catheter. The cen-ter of the openings in the splint catheter is at a certain dis-tance from the midpoint of the connection point for the shunt tube. The distance can be 40-60 mm, preferably 50 mm. The length of the oval openings is between 10 and 20 mm, preferably 16 mm.

So that the lateral openings in the back portion of the splint catheter can be temporarily closed when the catheter is introduced into the body, there is a closed tube piece in the splint catheter, or a rod of solid material, whose outer diameter is somewhat smaller than the inner diameter of the splint cath-eter. This part has a length such that, when in inserted posi-tion, it covers the side holes and projects beyond the back endof the catheter, making it possible to draw it out of the cath-eter as soon as the catheter is introduced far enough into the vessel for the holes to be within the blood vessel.

Attached to the shunt tube of the perfusion catheters by means of a tube connection is an ultra-filtration filter, which in turn is attached to the pressure side of a pump, so as to create the temporary portocaval shunt of the vena portae with the vena cava by means of the double catheter positioned in the vena cava during perfuslon.

The perfusion catheter can be produced from the materials usually used to mànufacture catheters. These materials are neutral toward body fluids; they can be sterilized without dif-ficulty and are sufficiently elastic, but at the samel suf-ficiently stiff and solid, to be introduced into blood vessels.
Suitable materials are polyolefines, polyfluoridated hydrocarbon polymers, synthetic rubbers, and the like; silicon rubber is a preferred material.

During application the splint catheter is inserted over its entire length in the vena cava. By legating the vessel from the outside the needed, separated spaces are created, as is the out-ward seal. Since making the ligature around the point of the splint catheter is often difficult due to the close proximity of the heart, a preferred embodiment of the invention displays an inflatable balloon in the area of the catheter point; the balloon is mounted from the outside and can be blown up by means of a feed line, thus creating a seal within the vessel and making the external ligature unnecessary.

The object of the invention will now be more closely described on the basis of the illustrations.

~ 3~75.'~

Fi~re 1 show a schematic longitudinal view of the part of the perfusion catheter that is inserted into the main vessel during perfusion.

Figure 2 is a cross-section of the double catheter along line A-A from figure 1.

Figure 3 is a cross-section of the double catheter along line B~B in figure 1, which indicates the position of the lateral openings.

Fig~ 4 shows the embodiment with mounted balloon.

In figure 1, the splint catheter is marked 1; its front end 6 is introduced into the vessel. Mounted on the splint catheter 1, the second catheter tube 3 is shorter and its end is tapered in such a way that the outer diameter of the double catheter in this area continuously increases. The back end of the second catheter tube runs off to the side from the back part of the splint cath-eter in the proximity of the shunt tube 2. The shunt tube is positioned at a distance of several cm from the back end of the splint catheter 1. At a certain distance from this connecting point, in the direction of its front end, the splint catheter 1 has a side opening 4. These openings are ideally oval in the longitudinal direction; each is several mm wide and about 10-20 mm, preferably 16 mm. The splint catheter has a length of about 250 mm; its inner diameter is 8-16 mm, preferably 10 mm, and the wall thickness is 1-2 mm. The center of the connecting point is preferably 20 mm from the back end of the catheter tube~ The second catheter tube is shorter in form and the front end is lo-cated about 80-120 mm behind the front end 6 of the splint catheter. The inner diameter of the second catheter tube can be 4-6 mm. The inner diameter of the shunt tube 2 is 4-6 mm and the wall thicknesses are between 1 and 2 mm.

P~3~7X~

A closed t~be piece or a s~lid rod 7 is inserted into the splint catheter 1 in order to close the hole ~ during insertion of the double cathe-ter into the vessel. The outer diameter of this part is such that in inserted position 4 it closes the lat-eral ho:Les, but can easily be drawn out of the splint catheter.

Not shown in figure 1 are the parts attached to the shunt tube 2 for producing the temporary portocaval shunt. In addition to a tube connection, these parts comprise an attached hemo-filter, to perform ultra-$iltration for partial detoxification of the portal blood, and a roller pump to pump the fluid. The tube connection between the ultra-Eiltration filter and the shunt tube
2 has a length of about 2.5 m. Between the filter and the tube pump or roller pump there is a tube piece with a rubber membrane for the removal of blood. The length of the tube, from the tube pump to the filter, is about 1.5 m and about 3 m of tube con-nection are necessary to attach the pump to the vena portae. The filter is a conventional ultra-filtration filter, with membrane sur~aces of 0.5 - 1.5 m , preferably 1 m ; the membranes have a exclusion border at a molecular weight of about 50,000. The ultra-filtrate removed from the actual filter is measured for volume in a calibrated measuring tank, with an accuracy of + 5 ml; near the filter, between the-filter and the shunt tube 2, is a tube connecting piece to refeed the drawn-off liqùid (the ultra-filtrate) into the tube system in the form of a replacement solution. This replacement solution is a suitable substitution fluid. The tube connections have an inner diameter of about 5 mm and an outer diameter of about 7 mm; they are produced of suit-able materials, preferably from synthetic rubbers or silicon rub-ber.

Figure 2 shows a double catheter in a cross-section along line A-A from figure 1, and makes clear the arrangement of the two catheter tubes in relation to each other.

~ '75~

Figure 3 shows the cross-section through the double catheter at another point along line B~B from figure l and makes clear how the lateral holes 4 are closed by the inserted rod 7 during insertion into the vessel. This cross-section shows an embodi-ment of the double catheter with two laterally positioned holes 4, which do not face but rather approach each other. Figures 2 and 3 show an embodiment of the double catheter with an egg~
shaped cross-section and give an approximation of the relative sizes of inner tubes l and 3.

Fig. 4 shows the embodiment with mounted balloon 8 on the front end of the splint catheter l. The feed line 9 for the inflation medium runs along the inside wall of the splint cath-eter l and runs off to the side, together with the shunt tube 2, at the back end of the catheter l. The figure indicates its course through the wall of the splint catheter. It is also pos-sible, however, to lead a portion of the feed line 9 within the shunt tube 2 and to later lead it out of that tube. At the end of the feed line 9 there is a so-called Luer cone/to attach the syringes or other feed devices for the inflation medium. The balloon has a length of 1.5 - 3 cm, ideally 2 cm. Its distance from the point at which the second catheter tube 3 branches off to the point at which the shunt tube 2 separates from the splint catheter l is 15 - 18 cm, preferably 17 cm. The balloon can be enlarged within the vessel until it has an outer diameter such that it lies closely against the inner wall of the vessel. In-creasing the outer diameter of the splint catheter 1 by 5 - lO mm by means of the balloon is generally sufficient. Materials gen-erally used for balloon catheters can be used for the balloon.

Claims (20)

The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows:
1. A double perfusion catheter of the type having individual catheter tubes solidly attached to each other, being of different lengths, cross-sections, and tapered front openings and having an attachment running off from the catheter tube with a larger diameter, wherein said double perfusion catheter comprises: a splint catheter; a catheter tube shorter than said splint catheter and mounted on the wall thereof with the back end of said catheter tube running off from the said wall of the splint catheter; a shunt tube connected at one point on the wall of said splint catheter and running off laterally at a distance from the back end of the splint catheter; and at least one opening, through the said wall of said splint catheter, located at a distance of from 40 to 60 mm from said connection point of said shunt tube.
2. Perfusion catheter as claimed in claim 1, wherein the double catheter has an oval or egg-shaped outer cross-section and the inner diameter of the splint catheter is larger than the inner diameter of the second catheter tube.
3. Perfusion catheter as claimed in claim 1, wherein the catheter tube runs off laterally from the splint catheter in the vicinity of the connection of the shunt tube to the splint catheter.
4. Perfusion catheter as claimed in claims 1, 2 or 3, wherein there are two staggered openings at the end of the catheter tube.
5. Perfusion catheter as claimed in claims 1, 2 or 3, wherein the distance from the center of the opening in the splint catheter to the center of the connection point of the shunt tube is 50 mm.
6. Perfusion catheter as claimed in claims 1, 2 or 3, wherein one or two openings in the splint catheter are oval in shape and have a length of about 10 - 20 mm, preferably 16 mm.
7. Perfusion catheter as claimed in claims 1, 2 or 3, wherein the inner diameter of the splint catheter is 8 to 16 mm and the inner diameter of the shunt tube is 5 mm.
8. Perfusion catheter as claimed in claims 1, 2 or 3, wherein a closed tube piece or rod, whose outer diameter is smaller than the inner diameter of the splint catheter, is placed inside the splint catheter over a length such that the lateral openings are thereby closed and the end of the rod projects beyond the back end of the splint catheter.
9. Perfusion catheter as claimed in claims 1, 2 or 3, wherein the said perfusion catheter is made of silicon rubber.
10. Perfusion catheter as claimed in claims 1, 2 or 3, wherein the splint catheter comprises an inflatable balloon at a slight distance from its tapered front end, said balloon having a feed line located within the splint catheter and, together with the shunt tube, branching off laterally at the back end of the catheter and having at its end, a Luer cone as a connection.
11. A double perfusion catheter for insertion, over its entire length, in the vena cava during isolated perfusion of the liver, said catheter comprising two individual tubes extending generally in parallel relationship and being solidly attached to each other, namely a first tube in the form of a splint catheter tube, and a second tube carried by, and having a shorter length and a smaller diameter than, said first tube, said first tube having a rear opening, a shunt tube laterally branching off from said first tube at a point spaced forwardly from said rear opening, a tapered front opening, and at least one lateral opening on the side of said first tube generally opposite the side on which said second tube is carried, said second tube having a tapered front opening at a point rearwardly of the front opening of said first tube, and having a rear portion which is open at its end and extends laterally away from the first-mentioned side of said first tube, and said lateral opening(s) in said first tube being located at a distance of from 40 to 60 mm from the center of the point of junction of said shunt tube with said first tube, such that upon full insertion of said catheter into the vena cava during isolated perfusion of the liver, isolated withdrawal of blood from the liver through said second tube in a rearward direction is made possible while, at the same time, circulation of blood, from said shunt tube as well as from said lateral opening(s), and thence through said first tube in a forward direction remains insured.
12. The catheter of claim 11, wherein the double catheter has an oval or egg-shaped outer cross-section and the inner diameter of the splint catheter tube is larger than the inner diameter of the second catheter tube.
13. The catheter of claim 11, wherein the second catheter tube extends laterally away from the splint catheter tube in the vicinity of the junction point for the shunt tube.
14. The catheter of claim 11, wherein there are two staggered openings at the end of the second catheter tube.
15. The catheter of claim 11, wherein the distance from the center of the opening in the splint catheter tube to the center of the junction point of the shunt tube is 50 mm.
16. The catheter of claim 11, wherein one or two openings in the splint catheter tube are oval in shape and have a length of about 10 - 20 mm, preferably about 16 mm.
17. The catheter of claim 11, wherein the inner diameter of the splint catheter tube is 8 to 16 mm and the inner diameter of the shunt tube is about 5 mm.
18. The catheter of claim 11, wherein a closed tube piece or rod, whose outer diameter is smaller than the inner diameter of the splint catheter tube, is placed inside the splint catheter tube through the rear end thereof over a length such that the lateral openings are thereby closed and the end of the rod projects beyond the rear end of the splint catheter tube.
19. The catheter of claim 11, wherein the catheter is made of silicon rubber.
20. The catheter of claim 11, wherein the splint catheter tube includes an inflatable balloon at a slight distance from its tapered front end, said balloon having a feed line which runs within the splint catheter tube and, together with the shunt tube, branches off laterally at the rear end of the catheter tube and has at its end a connection means in the form of a Luer cone.
CA000425810A 1982-04-20 1983-04-13 Perfusion catheter designed as a double catheter Expired CA1194752A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3214397.4 1982-04-20
DE3214397A DE3214397C2 (en) 1982-04-20 1982-04-20 Double lumen perfusion catheter

Publications (1)

Publication Number Publication Date
CA1194752A true CA1194752A (en) 1985-10-08

Family

ID=6161274

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000425810A Expired CA1194752A (en) 1982-04-20 1983-04-13 Perfusion catheter designed as a double catheter

Country Status (10)

Country Link
US (1) US4540402A (en)
EP (1) EP0093887B1 (en)
JP (1) JPS58190448A (en)
AT (1) ATE17322T1 (en)
CA (1) CA1194752A (en)
DE (2) DE3214397C2 (en)
DK (1) DK170483A (en)
ES (1) ES279899Y (en)
FI (1) FI73133C (en)
NO (1) NO154114C (en)

Families Citing this family (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE50867T1 (en) * 1985-06-20 1990-03-15 Siemens Ag METHOD AND EQUIPMENT FOR AUTOMATIC TRANSFER OF SMALL QUANTITIES OF LIQUID SAMPLES IN GAS CHROMATOGRAPHY.
JPH0741067B2 (en) * 1985-12-28 1995-05-10 正文 小出 Treatment device
DE3705637A1 (en) * 1987-02-21 1988-09-29 Bissendorf Peptide Gmbh DEVICE FOR REMOVING LOCALLY APPLIED ACTIVE SUBSTANCES AGAINST SOLID TUMORS
US4808156A (en) * 1987-03-09 1989-02-28 Dean Consuelo M Cannular instrument and method for inserting a cannular instrument into a vein
US4821715A (en) * 1988-02-16 1989-04-18 Downing Michael V Nasopharyngeal airway
US5069662A (en) * 1988-10-21 1991-12-03 Delcath Systems, Inc. Cancer treatment
JPH0751062Y2 (en) * 1989-01-13 1995-11-22 晴夫 高瀬 Suction tube for removing biological tissue
US5106368A (en) * 1990-04-20 1992-04-21 Cook Incorporated Collapsible lumen catheter for extracorporeal treatment
US5167623A (en) * 1990-12-27 1992-12-01 The Kendall Company Multilumen catheter
DE4105965A1 (en) * 1991-02-26 1992-08-27 Innovative Medizintechnik DOUBLE LUMEN CATHETER AND METHOD FOR PRODUCING AN IMPORT PROFILE ON THIS
US5219335A (en) * 1991-05-23 1993-06-15 Scimed Life Systems, Inc. Intravascular device such as introducer sheath or balloon catheter or the like and methods for use thereof
US6309379B1 (en) 1991-05-23 2001-10-30 Lloyd K. Willard Sheath for selective delivery of multiple intravascular devices and methods of use thereof
US5180364A (en) * 1991-07-03 1993-01-19 Robert Ginsburg Valved self-perfusing catheter guide
US5389087A (en) * 1991-09-19 1995-02-14 Baxter International Inc. Fully exchangeable over-the-wire catheter with rip seam and gated side port
US5324269A (en) * 1991-09-19 1994-06-28 Baxter International Inc. Fully exchangeable dual lumen over-the-wire dilatation catheter with rip seam
US5360414A (en) * 1992-10-08 1994-11-01 Yarger Richard J Tube for draining body cavities, viscera and wounds
US6620188B1 (en) * 1998-08-24 2003-09-16 Radiant Medical, Inc. Methods and apparatus for regional and whole body temperature modification
US6110168A (en) 1993-02-10 2000-08-29 Radiant Medical, Inc. Method and apparatus for controlling a patient's body temperature by in situ blood temperature modifications
US6033383A (en) * 1996-12-19 2000-03-07 Ginsburg; Robert Temperature regulating catheter and methods
US5837003A (en) * 1993-02-10 1998-11-17 Radiant Medical, Inc. Method and apparatus for controlling a patient's body temperature by in situ blood temperature modification
US6849083B2 (en) 1993-02-10 2005-02-01 Radiant Medical, Inc. Method and apparatus for controlling a patients's body temperature by in situ blood temperature modification
US5405341A (en) * 1993-06-03 1995-04-11 Med-Pro Design, Inc. Catheter with multiple lumens
US5318535A (en) * 1993-06-21 1994-06-07 Baxter International Inc. Low-profile dual-lumen perfusion balloon catheter with axially movable inner guide sheath
EP0711574A1 (en) * 1994-11-10 1996-05-15 Med-Pro Design, Inc. Catheter with dual round lumens
US6849069B1 (en) 1995-11-07 2005-02-01 Boston Scientitfic Corporation Medical device with tail(s) for assisting flow of urine
US6991614B2 (en) 1995-11-07 2006-01-31 Boston Scientific Scimed, Inc. Ureteral stent for improved patient comfort
US6186146B1 (en) 1996-08-30 2001-02-13 Delcath Systems Inc Cancer treatment method
US5879321A (en) * 1997-01-22 1999-03-09 The University Of Kentucky Research Foundation Portocaval-right atrial shunt
US5817046A (en) * 1997-07-14 1998-10-06 Delcath Systems, Inc. Apparatus and method for isolated pelvic perfusion
US5919163A (en) * 1997-07-14 1999-07-06 Delcath Systems, Inc. Catheter with slidable balloon
US6190352B1 (en) * 1997-10-01 2001-02-20 Boston Scientific Corporation Guidewire compatible port and method for inserting same
US6889082B2 (en) 1997-10-09 2005-05-03 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6610004B2 (en) 1997-10-09 2003-08-26 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6699231B1 (en) 1997-12-31 2004-03-02 Heartport, Inc. Methods and apparatus for perfusion of isolated tissue structure
JP4612186B2 (en) 1998-02-24 2011-01-12 ナビリスト メディカル， インコーポレイテッド High flow dialysis catheter and related methods
US6682551B1 (en) 1999-03-11 2004-01-27 Alsius Corporation Method and system for treating cardiac arrest using hypothermia
US6338727B1 (en) 1998-08-13 2002-01-15 Alsius Corporation Indwelling heat exchange catheter and method of using same
US6620189B1 (en) 2000-02-28 2003-09-16 Radiant Medical, Inc. Method and system for control of a patient's body temperature by way of a transluminally insertable heat exchange catheter
US6673098B1 (en) * 1998-08-24 2004-01-06 Radiant Medical, Inc. Disposable cassette for intravascular heat exchange catheter
US6196230B1 (en) 1998-09-10 2001-03-06 Percardia, Inc. Stent delivery system and method of use
JP2003534822A (en) * 1998-09-10 2003-11-25 パーカーディア，インコーポレイティド Implantable shunt device
US6332892B1 (en) 1999-03-02 2001-12-25 Scimed Life Systems, Inc. Medical device with one or more helical coils
US6460544B1 (en) 1999-03-11 2002-10-08 Alsius Corporation Method and apparatus for establishing and maintaining therapeutic hypothemia
SE516215C2 (en) 1999-07-10 2001-12-03 Argmed Kb Perfusion system and pump device and control system for use in the perfusion system
US8172783B1 (en) * 1999-12-30 2012-05-08 Advanced Cardiovascular Systems, Inc Conduit system for isolation of fluids in biological tissues
EP1230941A1 (en) * 2001-02-09 2002-08-14 Jean-Denis Rochat Double lumen needle
US6451045B1 (en) 2001-02-22 2002-09-17 Alsius Corporation Heat exchange catheter having a helically wrapped heat exchanger
US6719804B2 (en) 2001-04-02 2004-04-13 Scimed Life Systems, Inc. Medical stent and related methods
US20020188167A1 (en) * 2001-06-06 2002-12-12 Anthony Viole Multilumen catheter for minimizing limb ischemia
US7048680B2 (en) * 2001-06-06 2006-05-23 Orqis Medical Corporation Multilumen catheter for minimizing limb ischemia
US6620202B2 (en) 2001-10-16 2003-09-16 Scimed Life Systems, Inc. Medical stent with variable coil and related methods
EP1471969A4 (en) * 2002-02-05 2008-04-30 Univ Yale Single access dialysis needle
US7070582B2 (en) * 2002-08-09 2006-07-04 Boston Scientific Scimed, Inc. Injection devices that provide reduced outflow of therapeutic agents and methods of delivering therapeutic agents
US7416525B2 (en) 2003-09-18 2008-08-26 Myrakelle, Llc Rotary blood pump
US20050113631A1 (en) * 2003-11-12 2005-05-26 Bolling Steven F. Cannulae having a redirecting tip
US7445592B2 (en) 2004-06-10 2008-11-04 Orqis Medical Corporation Cannulae having reduced flow resistance
US20050277804A1 (en) * 2004-06-10 2005-12-15 Robert Pecor System including a cannula having reduced flow resistance
US20060047301A1 (en) * 2004-09-02 2006-03-02 Ogle Matthew F Emboli removal system with oxygenated flow
US7393181B2 (en) 2004-09-17 2008-07-01 The Penn State Research Foundation Expandable impeller pump
EA013420B1 (en) 2006-03-20 2010-04-30 Медикал Дивайс Воркс Нв Са A device for delivering medical treatment
AU2007230945B2 (en) 2006-03-23 2013-05-02 The Penn State Research Foundation Heart assist device with expandable impeller pump
WO2007115222A2 (en) 2006-03-31 2007-10-11 Orqis Medical Corporation Rotary blood pump
US20070282306A1 (en) * 2006-06-05 2007-12-06 Twincath, Llc Multi-lumen catheter with protected tip
US20090131967A1 (en) * 2007-11-16 2009-05-21 Hollis Jeffrey D Surgical trocar
DE102007056946A1 (en) * 2007-11-27 2009-05-28 Gunnar Pah Device for filtering blood
WO2009157408A1 (en) 2008-06-23 2009-12-30 テルモ株式会社 Blood pump apparatus
WO2010067682A1 (en) 2008-12-08 2010-06-17 Ntn株式会社 Centrifugal pump device
JP5378010B2 (en) 2009-03-05 2013-12-25 ソラテック コーポレーション Centrifugal pump device
WO2010101107A1 (en) 2009-03-06 2010-09-10 Ntn株式会社 Centrifugal pump device
US8535211B2 (en) 2009-07-01 2013-09-17 Thoratec Corporation Blood pump with expandable cannula
EP3490122B1 (en) 2009-07-29 2021-01-27 Thoratec Corporation Rotation drive device and centrifugal pump device
JP5443197B2 (en) 2010-02-16 2014-03-19 ソラテック コーポレーション Centrifugal pump device
JP5572832B2 (en) 2010-03-26 2014-08-20 ソーラテック コーポレイション Centrifugal blood pump device
JP5681403B2 (en) 2010-07-12 2015-03-11 ソーラテック コーポレイション Centrifugal pump device
JP5577506B2 (en) 2010-09-14 2014-08-27 ソーラテック コーポレイション Centrifugal pump device
US8485961B2 (en) 2011-01-05 2013-07-16 Thoratec Corporation Impeller housing for percutaneous heart pump
US8597170B2 (en) 2011-01-05 2013-12-03 Thoratec Corporation Catheter pump
US8591393B2 (en) 2011-01-06 2013-11-26 Thoratec Corporation Catheter pump
US9138518B2 (en) 2011-01-06 2015-09-22 Thoratec Corporation Percutaneous heart pump
JP5969979B2 (en) 2011-03-28 2016-08-17 ソーラテック コーポレイション Rotation drive device and centrifugal pump device using the same
US9205237B2 (en) 2011-07-13 2015-12-08 Khoury Medical Devices, Llc Single lumen distal perfusion sheath
US9017275B2 (en) 2011-07-13 2015-04-28 Khoury Medical Devices, Llc Distal perfusion sheath
US9555216B2 (en) 2011-07-13 2017-01-31 Khoury Medical Devices, Llc Distal perfusion sheath
US20130019872A1 (en) * 2011-07-20 2013-01-24 Bahman Guyuron Nasopharyngeal airway
JP6083929B2 (en) 2012-01-18 2017-02-22 ソーラテック コーポレイション Centrifugal pump device
US9446179B2 (en) 2012-05-14 2016-09-20 Thoratec Corporation Distal bearing support
GB2504176A (en) 2012-05-14 2014-01-22 Thoratec Corp Collapsible impeller for catheter pump
US9327067B2 (en) 2012-05-14 2016-05-03 Thoratec Corporation Impeller for catheter pump
US9872947B2 (en) 2012-05-14 2018-01-23 Tc1 Llc Sheath system for catheter pump
US8721517B2 (en) 2012-05-14 2014-05-13 Thoratec Corporation Impeller for catheter pump
US9421311B2 (en) 2012-07-03 2016-08-23 Thoratec Corporation Motor assembly for catheter pump
US9358329B2 (en) 2012-07-03 2016-06-07 Thoratec Corporation Catheter pump
EP4186557A1 (en) 2012-07-03 2023-05-31 Tc1 Llc Motor assembly for catheter pump
US9072864B2 (en) * 2012-11-28 2015-07-07 Ad-Tech Medical Instrument Corporation Catheter with depth electrode for dual-purpose use
US9278023B2 (en) 2012-12-14 2016-03-08 Zoll Circulation, Inc. System and method for management of body temperature
US9371826B2 (en) 2013-01-24 2016-06-21 Thoratec Corporation Impeller position compensation using field oriented control
US9556873B2 (en) 2013-02-27 2017-01-31 Tc1 Llc Startup sequence for centrifugal pump with levitated impeller
US11077294B2 (en) 2013-03-13 2021-08-03 Tc1 Llc Sheath assembly for catheter pump
US11033728B2 (en) 2013-03-13 2021-06-15 Tc1 Llc Fluid handling system
WO2014164136A1 (en) 2013-03-13 2014-10-09 Thoratec Corporation Fluid handling system
US9308302B2 (en) 2013-03-15 2016-04-12 Thoratec Corporation Catheter pump assembly including a stator
EP2968742B1 (en) 2013-03-15 2020-12-02 Tc1 Llc Catheter pump assembly including a stator
US9713663B2 (en) 2013-04-30 2017-07-25 Tc1 Llc Cardiac pump with speed adapted for ventricle unloading
US10052420B2 (en) 2013-04-30 2018-08-21 Tc1 Llc Heart beat identification and pump speed synchronization
WO2015160990A1 (en) 2014-04-15 2015-10-22 Thoratec Corporation Catheter pump introducer systems and methods
WO2015160979A1 (en) 2014-04-15 2015-10-22 Thoratec Corporation Catheter pump with access ports
WO2015160942A1 (en) 2014-04-15 2015-10-22 Thoratec Corporation Catheter pump with off-set motor position
WO2015160943A1 (en) 2014-04-15 2015-10-22 Thoratec Corporation Sensors for catheter pumps
EP3583973A1 (en) 2014-08-18 2019-12-25 Tc1 Llc Guide features for percutaneous catheter pump
US9623161B2 (en) 2014-08-26 2017-04-18 Tc1 Llc Blood pump and method of suction detection
WO2016118777A1 (en) 2015-01-22 2016-07-28 Thoratec Corporation Reduced rotational mass motor assembly for catheter pump
US9675738B2 (en) 2015-01-22 2017-06-13 Tc1 Llc Attachment mechanisms for motor of catheter pump
EP3804797A1 (en) 2015-01-22 2021-04-14 Tc1 Llc Motor assembly with heat exchanger for catheter pump
WO2016130846A1 (en) 2015-02-11 2016-08-18 Thoratec Corporation Heart beat identification and pump speed synchronization
WO2016130944A1 (en) 2015-02-12 2016-08-18 Thoratec Corporation System and method for controlling the position of a levitated rotor
US10371152B2 (en) 2015-02-12 2019-08-06 Tc1 Llc Alternating pump gaps
EP3626277A1 (en) 2015-02-13 2020-03-25 Tc1 Llc Impeller suspension mechanism for heart pump
US9907890B2 (en) 2015-04-16 2018-03-06 Tc1 Llc Catheter pump with positioning brace
CN107708610A (en) * 2015-04-30 2018-02-16 丝绸之路医药公司 System and method for being treated through conduit aorta petal
US10117983B2 (en) 2015-11-16 2018-11-06 Tc1 Llc Pressure/flow characteristic modification of a centrifugal pump in a ventricular assist device
EP3808402A1 (en) 2016-07-21 2021-04-21 Tc1 Llc Gas-filled chamber for catheter pump motor assembly
US11160970B2 (en) 2016-07-21 2021-11-02 Tc1 Llc Fluid seals for catheter pump motor assembly
CN111770731B (en) * 2017-11-24 2023-08-04 国立大学医院（新加坡）私人有限公司 Balloon anchoring type biopsy device

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US883583A (en) * 1906-03-05 1908-03-31 Joseph F Stallsmith Stomach-pump.
US2474665A (en) * 1946-02-26 1949-06-28 Frank J Guarino Pneumatic blood treating apparatus
US3833003A (en) * 1972-07-05 1974-09-03 A Taricco Intravascular occluding catheter
US4134402A (en) * 1976-02-11 1979-01-16 Mahurkar Sakharam D Double lumen hemodialysis catheter
DE2703087C2 (en) * 1977-01-26 1984-11-29 Günter van Dr.med. 4000 Düsseldorf Endert Double lumen catheter
US4299217A (en) * 1977-06-03 1981-11-10 Terumo Corporation Intravascular catheter
JPS5740997Y2 (en) * 1977-06-03 1982-09-08
DE3010841A1 (en) * 1980-03-21 1981-10-08 Ulrich Dr.med. 6936 Haag Uthmann CATHEDER
US4405313A (en) * 1982-01-29 1983-09-20 Sisley James R Figure-eight, dual-lumen catheter and method of using

Also Published As

Publication number Publication date
FI73133C (en) 1987-09-10
US4540402A (en) 1985-09-10
DK170483A (en) 1983-10-21
NO154114C (en) 1986-07-23
NO154114B (en) 1986-04-14
DK170483D0 (en) 1983-04-19
ATE17322T1 (en) 1986-01-15
DE3214397A1 (en) 1983-11-03
FI831273L (en) 1983-10-21
EP0093887B1 (en) 1986-01-08
ES279899Y (en) 1986-01-16
EP0093887A1 (en) 1983-11-16
NO831311L (en) 1983-10-21
DE3361762D1 (en) 1986-02-20
DE3214397C2 (en) 1984-07-26
FI73133B (en) 1987-05-29
ES279899U (en) 1985-06-01
JPS58190448A (en) 1983-11-07
FI831273A0 (en) 1983-04-15

Similar Documents

Publication Publication Date Title
CA1194752A (en) Perfusion catheter designed as a double catheter
JPS60158867A (en) Double cavity catheter for blood purifer in body
EP0000041B1 (en) An intravascular catheter
US3943929A (en) Multi-chamber container and method
US4795446A (en) Medical tube device
US4563170A (en) Device for in vivo purification of blood
US4299217A (en) Intravascular catheter
CA1112972A (en) Double lumen catheter
CA1167727A (en) Cannula
US4808158A (en) Vascular catheter
US4995865A (en) Multi-lumen catheters
US5053023A (en) Catheter for prolonged access
US3851646A (en) Connector for open heart surgery
KR20000075915A (en) Docking ports for medical fluid sets
GB1578153A (en) Catheter
JPS6129748B2 (en)
JPH10118191A (en) Probe for medical treatment
JPH06339529A (en) Multilumen catheter
GB1387361A (en) Closed drainage system for draining liquid from a body cavity
JPH09508303A (en) Reinforced microdialysis probe
US5810760A (en) Cerebral edema solute catheter and method of draining cerebral edema
JPH02116380A (en) Dual lumen catheter and its production
JP3345035B2 (en) Needle penetration catheter materials
CN111135366A (en) Medical lavage tube and medical lavage system
CN208823743U (en) A kind of PICC conduit

Legal Events

Date Code Title Description
MKEC Expiry (correction)
MKEX Expiry