CA1207206A - Catheter having a soft, deformable tip - Google Patents

Catheter having a soft, deformable tip

Info

Publication number
CA1207206A
CA1207206A CA000443789A CA443789A CA1207206A CA 1207206 A CA1207206 A CA 1207206A CA 000443789 A CA000443789 A CA 000443789A CA 443789 A CA443789 A CA 443789A CA 1207206 A CA1207206 A CA 1207206A
Authority
CA
Canada
Prior art keywords
catheter
tip member
tip
distal end
lumen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000443789A
Other languages
French (fr)
Inventor
Robert A. Van Tassel
Mark A. Rydell
Gilmore T. Schjeldahl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schneider USA Inc
Original Assignee
Angiomedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiomedics Inc filed Critical Angiomedics Inc
Application granted granted Critical
Publication of CA1207206A publication Critical patent/CA1207206A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/0069—Tip not integral with tube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1011—Multiple balloon catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems

Abstract

CATHETER WITH SOFT DEFORMABLE TIP
ABSTRACT OF THE DISCLOSURE
A catheter for insertion in a body orfice or blood vessel comprising an elongated tubular body with a soft, symmetrically deformable member on the distal end thereof for decreasing the likelihood of injury to body tissue upon the insertion and removal thereof. In one embodiment, the tip member comprises a toroidally shaped inflatable and non-distensible expandable "balloon" mounted on the end of the otherwise relatively rigid tip of the catheter. The catheter has a lumen extending the length thereof and communicating with the tip member whereby a fluid may be introduced to control the size, shape and firmness of the tip member. In a second embodiment, the soft deformable tip member comprises an annular plastic or rubber sleeve surrounding the otherwise rigid tip of the catheter and normally extending there beyond by a predetermined distance. The thickness or composition of the sleeve is varied about a circumferential ring so as to provide a preferred location for the collapse of the sleeve.

Description

~L2~

CATI IETER WITH SOF r DF FORMABLE TIP
BACKGROUND OF INVENTION
1. Field of the Invention:
This invention relates generally catheter structures adapted to be introduced into a living body, and more specifically to the design of a catheter which may be introduced and routed through the vascular system of a patient with a minimum of damage or trauma to endothelial tissue.
im r f Present day surgical procedures permi t the introduction of tubular catheters into the vascular system of a body. For example, angiographic catheters are commonly introduced into the femoral artery and routed through the arterial system and to the coronary ostium so that radiopaque contrast or medicaments may be injected as part of a diagnostic or treatment procedure. Typically9 such c;dtheters comprise elongated, 1~xible plastic tubes of a predetermined small diameter significantly less than the cross section of the vessels through which the catheter must pass.
Other f orms of catheters which the present invention may f ind use are those associated with cardiac pacemakers. Here, the catheter takes the form of a pacing lead which is typically made to pass through the subclavian vein and through the superior vena cava into the right ventrical of the heart. Here, the catheter takes the form of a flexible sheath surrounding elongated conductors which terminate at the distal end in one or more surface electrodes adapted to contact endocardial heart tissue.
Prior art, angiographic and other diagnostic catheters as well as cardiac pacing leads are generally formed from polyethylene, polyurethane, polypropylene or silicone rubber or other non-thrombogenic material. So that they may be passed through the vascular system without folding or buckling, they must possess a wall thickness and a hardness which is capable of damaging vascular tissue, especially where the distal tip of the catheter is blunt or possessed of a sharp edge. While perhaps rare, there
2~6 have been instances where small diameter catheters having sharp edged tips have been advanced through the wall of the aorta, resulting in the death of the patient.
SUMMARY OF THE INVENTION
The present invention obviates the above described problems inherent in certain prior art catheters through the inclusion of a soft, deformable member attached to the distal tip of the catheter. In one embodiment, the deformable tip member comprises an annular inflatable flexible, non-distensible "balloon" element attached to the distal end of the otherwise relatively rigid tip of the catheter. In this arrangement, the catheter itself is provided with a lumen extending substantially the entire length of the catheter and communicating with the deformable tip member whereby a fluid may be introduced to control the size, shape and firmness of the tip portion of the catheter. By selectively inflating the balloon tip, the effective area of the tip can be increased to reduce the overall force per unit area at the point of contact between the tip of the catheter and a bloocl vessel.
In a second embodiment, the soft deformable tip member comprises an annular plastic or rubber sleeve surrounding the otherwise rigid tip of the catheter and normally extending therebeyond by a predetermined distance. The thickness or composition of the sleeve is altered about a circumferential line so as to prs)vide a preferred location for the folding and collapse of the sleeve as the terminal end of the sleeve is forced against body tissues. When the sleeve is made to collapse, the effective area of contact between the deformable tip and the body tissue increases to again reduce the pressure or force per unit area applied to the tissue.
OBJECTS
It is accordingly a principal object of the present invention to provide a new and improved catheter arrangement for medical applications.

~2~

Another object of the invention is to provide a catheter with a soft, deformable tip to thereby reduce the likelihood of damage to vascular tissue as the ca theter is introduced and routed through the vascular system.
A still further object of the invention is to provide a catheter with an inflatable tip member whereby the shape and firrnness of the distal end of the catheter can be controlled through the introduction of a fluid at the proximal end of the catheter.
Yet another object of the invention is to provide a catheter with a soft9 deEormable tip in the form of a sleeve member of a predetermined wall thickness profile such that the deformable tip member will collapse in a predictable manner to effectively increase the overall area of contact between the distal tip and body tissue which it contacts.
These and other objects and advantages of the invention will become apparent to those skillecl in the art from the following detailed description of the preferred embodiments, especially when considered in conjunction with the accompanying drawings in which like numerals in the several views referred to corresponding parts.
DESCRIPTION OF THE DRAWINGS
Figure I shows the distal tip portion of a conventional, prior art angiographic or diagnostic catheter;
Figure 2 is a cross sectional view of a catheter having an inflatable tip secured thereto;
Figure 3 is a cross sectional view of a catheter having an inflatable, non-distensible tip and an elastomeric band or sleeve in fluid communication therewith;
Figure 4 is a cross sectional view of an angiographic catheter having a collapsable sleeve as its distal tip, the sleeve being illustrated in its uncompressed state;
Figure 5 is a partial cross sectional view of Figure 4 illustrating the sleeve in its collapsed state; and Figure 6 is a partial cross sectional view of an alternative arrangement of a deformable tip on a catheter.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
Referring first to Figure 1, there is illustrated a longitudinal cross section of the distal end portion of a typical, prior art angiographic catheter. l is seen as cornprising a predetermined length of flexible plastic tubing 10 having a central lumen 11 extending the length of the catheter thereof from its proximal end (not shown) to its distal end 12. The lumen 11 is provided so that angiographic dyes or other medicaments may be introduced into the catheter at its proximal end located outside the body and made to flow through the lumen to a predetermined site within the body at which the distal end 12 of the catheter is positioned.
It is to be especially noted that the distal tip 12 of the prior art catheter of Figure I terminates in an abrupt edge 13 which is relatively sharp and, depending upon the type of material usecl for the body of the catheter 10 may possess sufficient rigidity to cause damage to vascular tissue, especially the endotheliel layer ~unica intirna) lining the blood vessels as the catheter is routed through the vascular system.
To obviate this problem, in accordance with a first embodiment of the invention illustrated in Figure 2, the catheter body 10 .s provided with a double lumen, namely the lumen 11 for allowing the flow of angiographic dyes or other fluids and a further lumen 14 which also runs the entire length of the catheter. Secured to the distal tip of the catheter body is a flexible, non-distensible inflatable "balloon" member 15 which, in its expanded Norm, has the general shape of a toroid. The lumen 14 is arranged to communicate with the interior of the torus comprising the tip 15 while the lumen 11 communicates with the central opening 17 of that toroid. While fluid introduced into the lumen 11 at the proximal end of the catheter may ultimately be made to flow outwardly through the opening 17 of the soft, flexible tip 15, fluid introduced into the lumen 14 flows into the annular ~21r~7;~6 chamber 16 causing the tip rnember Jo become inflated. The tip member 15 is preferably formed from a bioaxially oriented or cross~linked polyolefin film and may have a thickness in the range of from 0.001 to 0.0025 inchesO
As such, when unflated or evacuated, it lacks rigidity and wraps about and conforms approximately to the shape of the end portion of the catheter body 10. However, once properly pressurized, it expands so as to increase the desired effective area of contact between the end of the catheter and any body tissue which it may abut as it is being routed or positioned within the body. The degree of inflation, of course, determines the degree of softness or deformability of the tip. Thus, the physician has considerable control over the tip properties of the catheter so that tissue damage will be rninimized.
The $oroidal balloon member 15 is preferably molded separate and apart from the catheter body 10 and then affixed thereto by thermal or chemical bonding but may be a cavity formed in the walls of the distal end of the catheter which, when filled with a fluid under pressure, causes the wall of the catheter itself to bulge.
Figure 3 illustrates an alternative forrn of the embodiment of Figure 2 which has been modified to incorporate a distensible elastomeric sleeve l8 for controlling the internal pressure of the non-extensible tip member 15. The distensible elastomeric sleeve 18 may be positioned at any point along the length of the catheter body 10 and, in fact, may be disposed at the extreme proximal end of the catheter at a location which remains outside of the body following its insertion in routing. The elastomeric sleeve is preferably disposed within a ring-like recess formed in the outside surface of the catheter body 10 and is suitably bonded in a fluid-tight fashion to the catheter body at its end edges thereof as indicated by numerals 19 and 20, respectively. A radial bore 21 extends from the recess surface of the catheter body to the secondary lumen l The radiai bore 21, as well as the portion of the lumen 14 distally thereof, and the chamber 16 of the deformable tip lS are filled with an incompressible fluid, and a suitable plug 22 is disposed within the lumen 14 at a point proximal of the radial bore 21.
When a force is applied to the tip member 15 in figure 3, the internal pressure of this tip member is increased causing bulging (inflation) of the elastomeric sleeve member 18 and a corresponding deflation of the tip mernber 15. The degree of deflation is, of course proportional to the force exerted on it which, in turn, is a function of the "stiffness" oE the elastomeric sleeve 18. A decrease in the volume in the tip member results in an increase in the area of contact between it and any mating surface against which it is forced.
Y~hen the sleeve 18 is located at a point external to the body, it may be suitably coupled to a transducer which will directly indicate the fluid pressure within the system causing it to expand.
With continued attention being directed to the tip member 15 in Figure 3, it has been found expeclient to incorporate a heavier toroidal ring as at 23 to define the annular opening 17. This ring has an outside diameter which is no greater than the internal diameter of any introducer through which the catheter must be passed during implantation. Using this construction, the tip member 15 will conform to a lurnen smaller than the fully extended diameter of the tip member 15 because, as the force bearing on the wall increases, the internal presssure in the tip member will decrease due to the expansion of the elastomeric sleeve 18.
In practice9 the lumen 14 may have a diameter in the range of from 0.002 inches to 0.004 inches extending from the tip member 15 through and including the radial side port 21. The lumen 14 may be continued to the proximal end of the catheter where the elastomeric sleeve 18 and its included side port 21 may be disposed.
As with the embodiment of Figure 2, the tip mernber 15 is preferably formed from a non-extensible polyolefin film and may have a 7~:~6 thickness range from 0.001 inch to 0.0025 inch. These dimensions and materials are set forth herein for illustrative purposes only and should not be considered as necessarily limiting the scope of the invention.
Referring next to Figure 4, there is shown an alternative preferred embodiment of a catheter having a soft, deformable distal tip member affixed thereto. As viewed in Figure 4, this tip member comprises a tubular sleeve 24 which surrounds and fits by means s)f a lap joint at the distal end of the catheter body 10 and the sleeve 24 extends beyond the distal end thereof by a predetermined length. Rather than being of a constant thickness, the walls of the flexible plastic sleeve 24 are shaped so that when the extreme tip or end 25 thereof is pushed against a stationary object with a predetermined low force, the tip will collapse to yield the configuration shown in Figure 5. More specifically, the wall thickness of the portion of the tip member 24 extending beyond the end of the catheter 10 is generally constant but at the location identified by numeral 27 is relieved about an annular line, i.e., made to be of a lesser thickness, so as to fold about that circumferential line as a hinge Likewise, the soft, compressible tip member 24 folds along the outside periphery of the end of the catheter as at 28 like a hinge. Instead of reducing the sleeve wall thickness to create a preferential hinge or fold line, it is also possible to achieve the desired folding pattern by having a discontinuity in the sleeve material so as to have a different (lower) stiffness than the adjacent material .
By properly choosing the durometer of the plastic material comprising the soft collapsible tip 24, it will posses a "memory" property so that when the tip is no longer compressed against a stationary object, it will again snap back to the shape illustrated in Figure l It has also been found expedient to increse the amount of material surrounding the central opening 29 in the tip as at 30. This increase in material defines a ring which stablizes and strengthens the opening preventing it from sagging.

~2~7;~
With reference to Figure 5, it can be seen that when the tip member collapses, the effective area of contact between it and the object against which it is pressed is increased to thereby decrease the effective pressure exerted by the catheter structure against that tissue.
With no limitation intended and for illustrative purposes only, the lumen of the catheter may have a diameter of 0.0~5 inches and a wall thickness of 0.0085 inches at its distal end. The soft tip member 24 in Figures 4 and 5 is preferably about 0.005 inches thick but reducing Jo about 0.004 inches thick about the circular hinge line 27. When in its undeformed state, the distal end may exhibit a cross-sectional area of about 0.0012 square inches and, when collapsed as in Figure 5, an area of 0.00~1 square inches, representing a 3.41 times increase in area.
Figure 6 illustrates a still further embodiment in which the catheter is Eitted at its distal end with a tubular cylindrical tip member 31 fabricated from silastic or some other soft, deformable plastic material.
When forces against an obstacle, the soft plastic tip will deform by spreading and bending to present an increased area of contact with respect to this obstacle.
The invention has been described herein in considerable detail, in order to comply with the Patent Statutes and to provide those skilled in the art with information needed to apply the novel principles, and to construct and use such specialized components as are required. However, it is to be understood that the invention can be carried out by specifically different equipment and devices, and at various modifications, both as to equipment details and operating procedures can be effected without departing from the scope of the invention itself. What is claimed is:

Claims (13)

The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows:
1. A cathether comprising:
(a) an elongated flexible tubular member having at least one lumen extending the length thereof; and (b) a soft, annular deformable tip member affixed to the distal end of said catheter, said tip member including a circumferential preferential fold line located sufficiently close to the distal end of said tip member to allow collapse of said tip member along said preferential fold line upon being pressed against a relatively stationary surface without occluding said lumen.
2. The catheter as in claim 1, wherein said tip member comprises:
(a) a -flexible, non-distensible, hollow fluid im-pervious container, the interior of said container being in fluid communication with a lumen in said tubular member.
3. The catheter as in claim 2, wherein said container is toroidal in shape.
4. The catheter as in claim 1, wherein said deformable tip member surrounds the distal end of said catheter.
5. The catheter as in claim 2, wherein said tip member is formed from a non-extensible polyolefin plastic film material.
6. The catheter as in claim 3, and further including a flexible plastic toroidal reinforcing ring disposed within the annular opening of said toroidal container.
7. The catheter as in claim 1, wherein said deformable tip member comprises:
(a) a flexible tubular sleeve member affixed to the distal end portion of said catheter and extending therebeyond for a predetermined distance, said flexible sleeve member having an annular zone defining said preferential fold line and located in the portion thereof extending beyond said distal end of said catheter.
8. The catheter as in Claim 7 wherein said deformable tip member has an opening in said end of said tip member.
9. The catheter as in Claim 8 wherein said opening is defined by an integrally formed reinforcing ring.
10. The catheter as in Claim 7 wherein said tip member is formed from polyurethane.
11. The catheter as in Claim 2 and further including:
(a) a distensible segment sealingly affixed about its perimeter to said flexible tubular member at a location proximal of said tip member; and (b) a radial side port formed through the wall of said tubular member beneath said distensible segment, said side port communicating with said lumen.
12. The catheter as in Claim 11 wherein said distensible segment comprises:
a) an elastomeric band surrounding said tubular member and covering said side port.
13. The catheter as in Claim 7 wherein the outer diameter of said sleeve member is the same as that of said elongated flexible tubular member.
CA000443789A 1983-08-08 1983-12-20 Catheter having a soft, deformable tip Expired CA1207206A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US520,996 1983-08-08
US06/520,996 US4531943A (en) 1983-08-08 1983-08-08 Catheter with soft deformable tip

Publications (1)

Publication Number Publication Date
CA1207206A true CA1207206A (en) 1986-07-08

Family

ID=24074909

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000443789A Expired CA1207206A (en) 1983-08-08 1983-12-20 Catheter having a soft, deformable tip

Country Status (9)

Country Link
US (1) US4531943A (en)
JP (1) JPS6040069A (en)
CA (1) CA1207206A (en)
DE (1) DE3341850A1 (en)
DK (1) DK166129C (en)
FR (1) FR2550454B1 (en)
GB (1) GB2144635B (en)
IT (1) IT1171896B (en)
NL (1) NL187049C (en)

Families Citing this family (350)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE33561E (en) * 1983-07-05 1991-03-26 E. I. Du Pont De Nemours And Company Balloon and manufacture thereof
USRE32983E (en) * 1983-07-05 1989-07-11 E. I. Du Pont De Nemours And Company Balloon and manufacture thereof
US4551292A (en) * 1984-04-05 1985-11-05 Angiomedics, Inc. Method for making a catheter with a soft, deformable tip
US4801297A (en) * 1984-06-01 1989-01-31 Edward Weck Incorporated Catheter having slit tip
US4921483A (en) * 1985-12-19 1990-05-01 Leocor, Inc. Angioplasty catheter
US4886506A (en) * 1986-12-23 1989-12-12 Baxter Travenol Laboratories, Inc. Soft tip catheter
EP0273618A3 (en) * 1986-12-23 1989-09-13 BAXTER INTERNATIONAL INC. (a Delaware corporation) Soft tip catheter
US4878495A (en) * 1987-05-15 1989-11-07 Joseph Grayzel Valvuloplasty device with satellite expansion means
US4863442A (en) * 1987-08-14 1989-09-05 C. R. Bard, Inc. Soft tip catheter
US5231994A (en) * 1987-10-27 1993-08-03 Dietrich Harmjanz Hose or tubular guide catheter
US4867174A (en) * 1987-11-18 1989-09-19 Baxter Travenol Laboratories, Inc. Guidewire for medical use
JPH01227766A (en) * 1988-03-04 1989-09-11 Yuichi Furukawa Catheter for angiography
US4884573A (en) * 1988-03-07 1989-12-05 Leocor, Inc. Very low profile angioplasty balloon catheter with capacity to use steerable, removable guidewire
US5078702A (en) * 1988-03-25 1992-01-07 Baxter International Inc. Soft tip catheters
US4898591A (en) * 1988-08-09 1990-02-06 Mallinckrodt, Inc. Nylon-PEBA copolymer catheter
DE3833361C2 (en) * 1988-09-30 1996-07-11 Hohla Kristian Catheter for angioplasty
JP2729275B2 (en) * 1988-10-05 1998-03-18 則雄 大工園 Heating device by laser light
US5017259A (en) * 1988-10-13 1991-05-21 Terumo Kabushiki Kaisha Preparation of catheter including bonding and then thermoforming
US4990138A (en) * 1989-07-18 1991-02-05 Baxter International Inc. Catheter apparatus, and compositions useful for producing same
US4976690A (en) * 1989-08-10 1990-12-11 Scimed Life Systems, Inc. Variable stiffness angioplasty catheter
US5019040A (en) * 1989-08-31 1991-05-28 Koshin Sangyo Kabushiki Kaisha Catheter
US5084016A (en) * 1989-09-05 1992-01-28 Freeman Andrew B Epidural catheter apparatus with an inflation fitting
US5024655A (en) * 1989-09-05 1991-06-18 Freeman Andrew B Epidural catheter apparatus and associated method
US5092839A (en) * 1989-09-29 1992-03-03 Kipperman Robert M Coronary thrombectomy
NL9000054A (en) * 1990-01-09 1991-08-01 Cordis Europ METHOD FOR MANUFACTURING A CATHETER
ATE113488T1 (en) * 1990-01-12 1994-11-15 Schneider Usa Inc TELESCOPIC GUIDE CATHETER SYSTEM.
US5279596A (en) * 1990-07-27 1994-01-18 Cordis Corporation Intravascular catheter with kink resistant tip
US5192290A (en) * 1990-08-29 1993-03-09 Applied Medical Resources, Inc. Embolectomy catheter
US5160559A (en) * 1990-10-31 1992-11-03 Scimed Life Systems, Inc. Method for forming a guide catheter tip bond
ES2098489T3 (en) * 1990-11-09 1997-05-01 Boston Scient Corp GUIDE WIRE TO CROSS OCCLUSIONS IN BLOOD GLASSES.
US5170802A (en) * 1991-01-07 1992-12-15 Medtronic, Inc. Implantable electrode for location within a blood vessel
US5308325A (en) * 1991-01-28 1994-05-03 Corpak, Inc. Retention balloon for percutaneous catheter
US5439444A (en) * 1991-01-28 1995-08-08 Corpak, Inc. Pre-formed member for percutaneous catheter
US5188619A (en) * 1991-04-24 1993-02-23 Gene E. Myers Enterprises, Inc. Internal thoractic artery catheter
US5330428A (en) * 1991-05-14 1994-07-19 Scimed Life Systems, Inc. Dilatation catheter having a random copolymer balloon
US5240537A (en) * 1991-07-01 1993-08-31 Namic U.S.A. Corporation Method for manufacturing a soft tip catheter
US5308342A (en) * 1991-08-07 1994-05-03 Target Therapeutics, Inc. Variable stiffness catheter
US5333620A (en) * 1991-10-30 1994-08-02 C. R. Bard, Inc. High performance plastic coated medical guidewire
US5334169A (en) * 1992-05-11 1994-08-02 American Interventional Technologies, Inc. Reinforced catheter with thin monolithic walls
US5772590A (en) * 1992-06-30 1998-06-30 Cordis Webster, Inc. Cardiovascular catheter with laterally stable basket-shaped electrode array with puller wire
US5782239A (en) 1992-06-30 1998-07-21 Cordis Webster, Inc. Unique electrode configurations for cardiovascular electrode catheter with built-in deflection method and central puller wire
US5531721A (en) * 1992-07-02 1996-07-02 Scimed Life Systems, Inc. Multiple member intravascular guide catheter
US5348538A (en) * 1992-09-29 1994-09-20 Scimed Life Systems, Inc. Shrinking balloon catheter having nonlinear or hybrid compliance curve
US5358493A (en) * 1993-02-18 1994-10-25 Scimed Life Systems, Inc. Vascular access catheter and methods for manufacture thereof
DE69412082T2 (en) * 1993-04-09 1998-12-03 Schneider Usa Inc DILATATION CATHETER WITH A SOFT BUFFER TIP
US5545149A (en) * 1993-06-25 1996-08-13 Medtronic, Inc. Method of catheter segment attachment
US5951495A (en) * 1993-12-22 1999-09-14 Scimed Life Systems, Inc. Catheter having an adhesive braid wire constraint and method of manufacture
US5954651A (en) 1993-08-18 1999-09-21 Scimed Life Systems, Inc. Catheter having a high tensile strength braid wire constraint
US6673025B1 (en) 1993-12-01 2004-01-06 Advanced Cardiovascular Systems, Inc. Polymer coated guidewire
DE69428721T2 (en) * 1993-12-10 2002-06-20 Schneider Usa Inc guide catheter
CA2135143C (en) * 1993-12-22 2006-01-03 Todd A. Berg Catheter joint with restraining device
CA2137116A1 (en) * 1994-01-07 1995-07-08 Todd A. Berg Catheter joint with counterbore
US5571073A (en) * 1994-01-28 1996-11-05 Cordis Corporation Catheter flexible tip assembly
US5470307A (en) * 1994-03-16 1995-11-28 Lindall; Arnold W. Catheter system for controllably releasing a therapeutic agent at a remote tissue site
US5509910A (en) * 1994-05-02 1996-04-23 Medtronic, Inc. Method of soft tip attachment for thin walled catheters
DE69515246T2 (en) * 1994-10-20 2000-09-07 Interventional Technologies Process for the production of a polymer material with improved mechanical properties
AU4605896A (en) * 1995-01-04 1996-07-24 Medtronic, Inc. Improved method of soft tip forming
US6176842B1 (en) 1995-03-08 2001-01-23 Ekos Corporation Ultrasound assembly for use with light activated drugs
US6210356B1 (en) 1998-08-05 2001-04-03 Ekos Corporation Ultrasound assembly for use with a catheter
US5857464A (en) * 1995-06-07 1999-01-12 Desai; Jawahar M. Catheter for media injection
US6052612A (en) 1995-06-07 2000-04-18 Desai; Jawahar M. Catheter for media injection
US5803083A (en) * 1995-11-09 1998-09-08 Cordis Corporation Guiding catheter with ultrasound imaging capability
US5951929A (en) * 1995-12-12 1999-09-14 Medi-Dyne Inc. Method for forming a catheter having overlapping welds
US5772641A (en) * 1995-12-12 1998-06-30 Medi-Dyne Inc. Overlapping welds for catheter constructions
US6103037A (en) * 1995-12-12 2000-08-15 Medi-Dyne Inc. Method for making a catheter having overlapping welds
FR2744009B1 (en) * 1996-01-31 1998-03-27 Medicard SURGICAL INSTRUMENT, IN PARTICULAR FOR ALLOWING THE EXTRACTION OF PATHOLOGICAL VENOUS STONES, SUCH AS VARICIES
US6053900A (en) * 1996-02-16 2000-04-25 Brown; Joe E. Apparatus and method for delivering diagnostic and therapeutic agents intravascularly
US5728132A (en) * 1996-04-08 1998-03-17 Tricardia, L.L.C. Self-sealing vascular access device
US5836926A (en) * 1996-05-13 1998-11-17 Schneider (Usa) Inc Intravascular catheter
US6042578A (en) * 1996-05-13 2000-03-28 Schneider (Usa) Inc. Catheter reinforcing braids
US5762637A (en) * 1996-08-27 1998-06-09 Scimed Life Systems, Inc. Insert molded catheter tip
US6193670B1 (en) 1997-02-14 2001-02-27 Tricardia, Llc Hemostatic agent delivery device having built-in pressure sensor
US5855559A (en) * 1997-02-14 1999-01-05 Tricardia, Inc. Hemostatic agent delivery device having built-in pressure sensor
US6723063B1 (en) 1998-06-29 2004-04-20 Ekos Corporation Sheath for use with an ultrasound element
WO1998048711A1 (en) * 1997-05-01 1998-11-05 Ekos Corporation Ultrasound catheter
US6676626B1 (en) * 1998-05-01 2004-01-13 Ekos Corporation Ultrasound assembly with increased efficacy
US6582392B1 (en) 1998-05-01 2003-06-24 Ekos Corporation Ultrasound assembly for use with a catheter
US7455646B2 (en) * 1997-06-04 2008-11-25 Advanced Cardiovascular Systems, Inc. Polymer coated guide wire
US7494474B2 (en) * 1997-06-04 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymer coated guidewire
US6007575A (en) * 1997-06-06 1999-12-28 Samuels; Shaun Laurence Wilkie Inflatable intraluminal stent and method for affixing same within the human body
US6048338A (en) * 1997-10-15 2000-04-11 Scimed Life Systems, Inc. Catheter with spiral cut transition member
US5891110A (en) * 1997-10-15 1999-04-06 Scimed Life Systems, Inc. Over-the-wire catheter with improved trackability
US5908435A (en) * 1997-10-23 1999-06-01 Samuels; Shaun L. W. Expandable lumen device and method of use
US6036682A (en) * 1997-12-02 2000-03-14 Scimed Life Systems, Inc. Catheter having a plurality of integral radiopaque bands
US6402720B1 (en) 1997-12-22 2002-06-11 Cordis Corporation Balloon catheter with elongated flexible tip
US6149996A (en) * 1998-01-15 2000-11-21 Schneider (Usa) Inc. Molded tip and tubing and method of making same
US6129707A (en) 1998-01-21 2000-10-10 Advanced Cardiovascular Systems, Inc. Intravascular catheter with expanded distal tip
US5984946A (en) * 1998-02-27 1999-11-16 Gupta; Mukesh Diagnostic and guiding catheter
US6113579A (en) * 1998-03-04 2000-09-05 Scimed Life Systems, Inc. Catheter tip designs and methods for improved stent crossing
US6517515B1 (en) 1998-03-04 2003-02-11 Scimed Life Systems, Inc. Catheter having variable size guide wire lumen
US6171297B1 (en) 1998-06-30 2001-01-09 Schneider (Usa) Inc Radiopaque catheter tip
US7004962B2 (en) * 1998-07-27 2006-02-28 Schneider (Usa), Inc. Neuroaneurysm occlusion and delivery device and method of using same
US6464684B1 (en) 1998-09-09 2002-10-15 Scimed Life Systems, Inc. Catheter having regions of differing braid densities and methods of manufacture therefor
US6312402B1 (en) 1998-09-24 2001-11-06 Ekos Corporation Ultrasound catheter for improving blood flow to the heart
US6245053B1 (en) 1998-11-09 2001-06-12 Medtronic, Inc. Soft tip guiding catheter and method of fabrication
US6591472B1 (en) 1998-12-08 2003-07-15 Medtronic, Inc. Multiple segment catheter and method of fabrication
US6264630B1 (en) 1998-12-23 2001-07-24 Scimed Life Systems, Inc. Balloon catheter having an oscillating tip configuration
US5997546A (en) * 1999-01-07 1999-12-07 Ballard Medical Products Gastric balloon catheter with improved balloon orientation
DE60042316D1 (en) * 1999-01-28 2009-07-16 Salviac Ltd CATHETER WITH EXPANDABLE END CUT
US6270484B1 (en) 1999-02-17 2001-08-07 Inbae Yoon Safety penetrating instrument with expandible portion and method of penetrating anatomical cavity
US6231551B1 (en) * 1999-03-01 2001-05-15 Coaxia, Inc. Partial aortic occlusion devices and methods for cerebral perfusion augmentation
US6146370A (en) * 1999-04-07 2000-11-14 Coaxia, Inc. Devices and methods for preventing distal embolization from the internal carotid artery using flow reversal by partial occlusion of the external carotid artery
US6500285B2 (en) 1999-08-23 2002-12-31 Scimed Life Systems, Inc. Method of making a catheter having interlocking ribbed bond regions
US6738661B1 (en) * 1999-10-22 2004-05-18 Biosynergetics, Inc. Apparatus and methods for the controllable modification of compound concentration in a tube
US6575959B1 (en) 1999-12-27 2003-06-10 Scimed Life Systems, Inc. Catheter incorporating an insert molded hub and method of manufacturing
US6322586B1 (en) 2000-01-10 2001-11-27 Scimed Life Systems, Inc. Catheter tip designs and method of manufacture
US6491670B1 (en) * 2000-04-04 2002-12-10 Duke University Miniaturized surgical instruments especially useful for the opthalmologic surgical procedures and methods of making the same
CN1447669A (en) 2000-08-18 2003-10-08 阿特里泰克公司 Expandable implant devices for filtering blood flow from atrial appendages
US8086314B1 (en) 2000-09-27 2011-12-27 Cvrx, Inc. Devices and methods for cardiovascular reflex control
US6850801B2 (en) 2001-09-26 2005-02-01 Cvrx, Inc. Mapping methods for cardiovascular reflex control devices
US7158832B2 (en) * 2000-09-27 2007-01-02 Cvrx, Inc. Electrode designs and methods of use for cardiovascular reflex control devices
US20080167699A1 (en) * 2000-09-27 2008-07-10 Cvrx, Inc. Method and Apparatus for Providing Complex Tissue Stimulation Parameters
US7616997B2 (en) * 2000-09-27 2009-11-10 Kieval Robert S Devices and methods for cardiovascular reflex control via coupled electrodes
US7623926B2 (en) 2000-09-27 2009-11-24 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US20080177348A1 (en) * 2000-09-27 2008-07-24 Cvrx, Inc. Electrode contact configurations for an implantable stimulator
US7840271B2 (en) 2000-09-27 2010-11-23 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US6985774B2 (en) 2000-09-27 2006-01-10 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US6522926B1 (en) 2000-09-27 2003-02-18 Cvrx, Inc. Devices and methods for cardiovascular reflex control
US7499742B2 (en) * 2001-09-26 2009-03-03 Cvrx, Inc. Electrode structures and methods for their use in cardiovascular reflex control
US6623504B2 (en) 2000-12-08 2003-09-23 Scimed Life Systems, Inc. Balloon catheter with radiopaque distal tip
US6979343B2 (en) * 2001-02-14 2005-12-27 Ev3 Inc. Rolled tip recovery catheter
US6595980B1 (en) 2001-02-23 2003-07-22 Coaxia, Inc. Devices and methods for preventing distal embolization using flow reversal by occlusion of the brachiocephalic artery
US6887227B1 (en) * 2001-02-23 2005-05-03 Coaxia, Inc. Devices and methods for preventing distal embolization from the vertebrobasilar artery using flow reversal
JP2004531310A (en) * 2001-04-16 2004-10-14 サイティック コーポレイション Medical device with non-injury end
US6830579B2 (en) * 2001-05-01 2004-12-14 Coaxia, Inc. Devices and methods for preventing distal embolization using flow reversal and perfusion augmentation within the cerebral vasculature
US20020188223A1 (en) 2001-06-08 2002-12-12 Edward Perez Devices and methods for the expression of bodily fluids from an incision
US6652507B2 (en) 2001-07-03 2003-11-25 Scimed Life Systems, Inc. Intravascular catheter having multi-layered tip
US6533800B1 (en) * 2001-07-25 2003-03-18 Coaxia, Inc. Devices and methods for preventing distal embolization using flow reversal in arteries having collateral blood flow
US7201763B2 (en) * 2001-10-24 2007-04-10 Boston Scientific Scimed, Inc. Distal balloon waist material relief and method of manufacture
US20040019318A1 (en) * 2001-11-07 2004-01-29 Wilson Richard R. Ultrasound assembly for use with a catheter
JP4279676B2 (en) * 2001-12-03 2009-06-17 イコス コーポレイション Small vessel ultrasound catheter
ATE520362T1 (en) 2001-12-03 2011-09-15 Ekos Corp CATHETER WITH MULTIPLE ULTRASONIC EMITTING PARTS
US7018346B2 (en) 2001-12-18 2006-03-28 Scimed Life Systems, Inc. Guide wire with adjustable flexibility
US6945970B2 (en) 2001-12-27 2005-09-20 Scimed Life Systems, Inc. Catheter incorporating a curable polymer layer to control flexibility and method of manufacture
AU2003212481A1 (en) 2002-02-28 2003-09-09 Ekos Corporation Ultrasound assembly for use with a catheter
US8226629B1 (en) 2002-04-01 2012-07-24 Ekos Corporation Ultrasonic catheter power control
US20060253056A1 (en) * 2002-04-04 2006-11-09 Advanced Medical Optics, Inc. Multi-purpose phacoemulsification needle
US7037296B2 (en) * 2002-04-04 2006-05-02 Advanced Medical Optics, Inc. Curved multi-purpose phacoemulsification needle
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7617005B2 (en) * 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US6866655B2 (en) 2002-04-23 2005-03-15 Scimed Life Systems, Inc. Medical device with atraumatic tip
US9017308B2 (en) 2002-05-21 2015-04-28 Boston Scientific Scimed, Inc. Insert molded hub and strain relief
US7115134B2 (en) * 2002-07-22 2006-10-03 Chambers Technology, Llc. Catheter with flexible tip and shape retention
US6921371B2 (en) 2002-10-14 2005-07-26 Ekos Corporation Ultrasound radiating members for catheter
US20040106901A1 (en) * 2002-11-30 2004-06-03 Letson William W. Catheter having a balloon member invertedly attached thereto
US20040103987A1 (en) * 2002-11-30 2004-06-03 Triebes Thomas Gregory Process for producing unitary component and a catheter having a unitary component
US20040106899A1 (en) * 2002-11-30 2004-06-03 Mcmichael Donald J. Gastric balloon catheter with improved balloon orientation
US7534224B2 (en) * 2002-11-30 2009-05-19 Kimberly-Clark Worldwide, Inc. Catheter with unitary component
US7124489B2 (en) * 2002-11-30 2006-10-24 Kimberly-Clark Worldwide, Inc. Process for producing a catheter
US7771372B2 (en) * 2003-01-03 2010-08-10 Ekos Corporation Ultrasonic catheter with axial energy field
US7322988B2 (en) * 2003-01-17 2008-01-29 Boston Scientific Scimed, Inc. Methods of forming catheters with soft distal tips
US7438712B2 (en) 2003-03-05 2008-10-21 Scimed Life Systems, Inc. Multi-braid exterior tube
JP4898992B2 (en) 2003-04-14 2012-03-21 クック メディカル テクノロジーズ エルエルシー Large diameter delivery catheter / sheath
EP1619995A2 (en) * 2003-04-22 2006-02-01 Ekos Corporation Ultrasound enhanced central venous catheter
EP1631343B1 (en) 2003-04-28 2007-11-14 Cook Incorporated Flexible introducer sheath with varying durometer
US7597830B2 (en) * 2003-07-09 2009-10-06 Boston Scientific Scimed, Inc. Method of forming catheter distal tip
US20050038381A1 (en) * 2003-08-11 2005-02-17 Kimberly-Clark Worldwide, Inc. Catheter having a balloon member recessedly attached thereto
US7824392B2 (en) * 2003-08-20 2010-11-02 Boston Scientific Scimed, Inc. Catheter with thin-walled braid
US7615043B2 (en) 2003-08-20 2009-11-10 Boston Scientific Scimed, Inc. Medical device incorporating a polymer blend
US8187627B2 (en) * 2003-09-05 2012-05-29 Loma Linda University Medical Center Dressing delivery system for internal wounds
US7480532B2 (en) 2003-10-22 2009-01-20 Cvrx, Inc. Baroreflex activation for pain control, sedation and sleep
CN1925882A (en) * 2003-11-15 2007-03-07 梅德拉股份有限公司 Catheter for diagnostic imaging and therapeutic procedures
US7955313B2 (en) * 2003-12-17 2011-06-07 Boston Scientific Scimed, Inc. Composite catheter braid
US20050137687A1 (en) 2003-12-23 2005-06-23 Sadra Medical Heart valve anchor and method
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US7381219B2 (en) 2003-12-23 2008-06-03 Sadra Medical, Inc. Low profile heart valve and delivery system
US20050137694A1 (en) 2003-12-23 2005-06-23 Haug Ulrich R. Methods and apparatus for endovascularly replacing a patient's heart valve
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US7445631B2 (en) 2003-12-23 2008-11-04 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
EP2529699B1 (en) 2003-12-23 2014-01-29 Sadra Medical, Inc. Repositionable heart valve
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8951299B2 (en) 2003-12-23 2015-02-10 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US7329279B2 (en) 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US20120041550A1 (en) 2003-12-23 2012-02-16 Sadra Medical, Inc. Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US20050149176A1 (en) * 2003-12-29 2005-07-07 Scimed Life Systems, Inc. Selectively light curable support members for medical devices
US20050209578A1 (en) * 2004-01-29 2005-09-22 Christian Evans Edward A Ultrasonic catheter with segmented fluid delivery
US7972350B2 (en) * 2004-01-29 2011-07-05 Boston Scientific Scimed, Inc. Catheter tip
US7201737B2 (en) * 2004-01-29 2007-04-10 Ekos Corporation Treatment of vascular occlusions using elevated temperatures
US8221387B2 (en) * 2004-02-24 2012-07-17 Boston Scientific Scimed, Inc. Catheter having an improved distal tip
US20050234499A1 (en) * 2004-04-19 2005-10-20 Scimed Life Systems, Inc. Multi-lumen balloon catheter including manifold
US7331948B2 (en) 2004-06-18 2008-02-19 Medtronic, Inc. Catheter and catheter fabrication method
US7662144B2 (en) 2004-06-22 2010-02-16 Boston Scientific Scimed, Inc. Catheter shaft with improved manifold bond
US20060004417A1 (en) * 2004-06-30 2006-01-05 Cvrx, Inc. Baroreflex activation for arrhythmia treatment
US20080249420A1 (en) * 2004-10-14 2008-10-09 Crossman Arthur W Vascular Catheter Device and Related Methods of Using the Same
KR100714682B1 (en) * 2004-12-02 2007-05-04 삼성전자주식회사 File system path processing device and method thereof
US7828790B2 (en) * 2004-12-03 2010-11-09 Boston Scientific Scimed, Inc. Selectively flexible catheter and method of use
US7815599B2 (en) 2004-12-10 2010-10-19 Boston Scientific Scimed, Inc. Catheter having an ultra soft tip and methods for making the same
US7744574B2 (en) * 2004-12-16 2010-06-29 Boston Scientific Scimed, Inc. Catheter tip to reduce wire lock
US7976518B2 (en) 2005-01-13 2011-07-12 Corpak Medsystems, Inc. Tubing assembly and signal generator placement control device and method for use with catheter guidance systems
DE102005003632A1 (en) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Catheter for the transvascular implantation of heart valve prostheses
EP1871286A2 (en) * 2005-04-18 2008-01-02 Salviac Limited A retrieval catheter
US20060253099A1 (en) * 2005-04-21 2006-11-09 Medtronic Vascular, Inc. Guiding catheter with resiliently compressible occluder
US7962208B2 (en) 2005-04-25 2011-06-14 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
WO2006138741A1 (en) * 2005-06-17 2006-12-28 Abbott Laboratories Method of reducing rigidity of angioplasty balloon sections
US20080188928A1 (en) * 2005-09-16 2008-08-07 Amr Salahieh Medical device delivery sheath
JP4867250B2 (en) * 2005-09-26 2012-02-01 株式会社ジェイ・エム・エス Cannula
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
WO2007076045A2 (en) * 2005-12-24 2007-07-05 Crossman Arthur W Circumferential ablation guide wire system and related method of using the same
US8109879B2 (en) * 2006-01-10 2012-02-07 Cardiac Pacemakers, Inc. Assessing autonomic activity using baroreflex analysis
EP1988851A2 (en) 2006-02-14 2008-11-12 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US8287484B2 (en) * 2006-05-02 2012-10-16 Abbott Medical Optics Inc. Multi-purpose phacoemulsification needle
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US20070260173A1 (en) * 2006-05-05 2007-11-08 Alcon, Inc. Irrigation/aspiration tip
US20080125752A1 (en) * 2006-08-09 2008-05-29 Boston Scientific Scimed, Inc. Catheter assembly having a modified reinforcement layer
US8876754B2 (en) 2006-08-31 2014-11-04 Bayer Medical Care Inc. Catheter with filtering and sensing elements
AU2007310986B2 (en) 2006-10-18 2013-07-04 Boston Scientific Scimed, Inc. Inducing desirable temperature effects on body tissue
US8192363B2 (en) 2006-10-27 2012-06-05 Ekos Corporation Catheter with multiple ultrasound radiating members
US8945058B2 (en) * 2006-11-22 2015-02-03 Applied Medical Resources Corporation Trocar cannula with atraumatic tip
US10182833B2 (en) 2007-01-08 2019-01-22 Ekos Corporation Power parameters for ultrasonic catheter
US7765015B2 (en) * 2007-01-12 2010-07-27 Cardiac Pacemakers, Inc. Lead with inflatable fixation mechanism
US20080183103A1 (en) * 2007-01-25 2008-07-31 Cardiac Pacemakers, Inc. Bulbous distal ended catheter
US8249705B1 (en) 2007-03-20 2012-08-21 Cvrx, Inc. Devices, systems, and methods for improving left ventricular structure and function using baroreflex activation therapy
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US20090132002A1 (en) * 2007-05-11 2009-05-21 Cvrx, Inc. Baroreflex activation therapy with conditional shut off
EP2494932B1 (en) 2007-06-22 2020-05-20 Ekos Corporation Apparatus for treatment of intracranial hemorrhages
US8594794B2 (en) 2007-07-24 2013-11-26 Cvrx, Inc. Baroreflex activation therapy with incrementally changing intensity
BR112012021347A2 (en) 2008-02-26 2019-09-24 Jenavalve Tecnology Inc stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US9101735B2 (en) * 2008-07-07 2015-08-11 Intuitive Surgical Operations, Inc. Catheter control systems
US9233195B2 (en) * 2008-09-24 2016-01-12 Art, Limited Composite irrigation/aspiration needle with ball tip
US9351871B2 (en) * 2008-11-12 2016-05-31 Alcon Research, Ltd. Distal plastic end infusion/aspiration tip
ES2708123T3 (en) 2009-04-24 2019-04-08 Imds R&D Bv Guide wire support system and guide wire
US8545462B2 (en) 2009-11-11 2013-10-01 Alcon Research, Ltd. Patch for irrigation/aspiration tip
US10105485B2 (en) * 2010-04-16 2018-10-23 MRI Interventions, Inc. MRI surgical systems including MRI-compatible surgical cannulae for transferring a substance to and/or from a patient
CN103002833B (en) 2010-05-25 2016-05-11 耶拿阀门科技公司 Artificial heart valve and comprise artificial heart valve and support through conduit carry interior prosthese
US10231721B2 (en) 2010-06-24 2019-03-19 St. Croix Surgical Systems, Llc Failsafe percutaneous wound barrier
CN106073946B (en) 2010-09-10 2022-01-04 西美蒂斯股份公司 Valve replacement device, delivery device for a valve replacement device and method of producing a valve replacement device
US9339442B2 (en) 2010-09-27 2016-05-17 Avent, Inc. Multi-balloon dilation device for placing catheter tubes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US8784361B2 (en) 2010-12-07 2014-07-22 Alcon Research, Ltd. Combined coaxial and bimanual irrigation/aspiration apparatus
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
EP4119095A1 (en) 2011-03-21 2023-01-18 Cephea Valve Technologies, Inc. Disk-based valve apparatus
CA2832311A1 (en) 2011-04-08 2012-11-29 Covidien Lp Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
JP5829833B2 (en) * 2011-04-21 2015-12-09 株式会社グッドマン Balloon catheter
EP2701623B1 (en) 2011-04-25 2016-08-17 Medtronic Ardian Luxembourg S.à.r.l. Apparatus related to constrained deployment of cryogenic balloons for limited cryogenic ablation of vessel walls
EP2520251A1 (en) 2011-05-05 2012-11-07 Symetis SA Method and Apparatus for Compressing Stent-Valves
US11458290B2 (en) 2011-05-11 2022-10-04 Ekos Corporation Ultrasound system
WO2013009975A1 (en) 2011-07-12 2013-01-17 Boston Scientific Scimed, Inc. Coupling system for medical devices
AU2012287321A1 (en) * 2011-07-25 2014-02-13 Acclarent, Inc. Devices and methods for transnasal dilation and irrigation of the sinuses
CN103930148A (en) * 2011-07-28 2014-07-16 阿克拉伦特公司 Improved device and method for dilating an airway stenosis
WO2013036772A1 (en) 2011-09-08 2013-03-14 Corpak Medsystems, Inc. Apparatus and method used with guidance system for feeding and suctioning
JP2014532450A (en) 2011-10-21 2014-12-08 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Locking catheter hub
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
US9433725B2 (en) 2011-12-23 2016-09-06 Alcon Research, Ltd. Combined coaxial and bimanual irrigation/aspiration apparatus
US10172708B2 (en) 2012-01-25 2019-01-08 Boston Scientific Scimed, Inc. Valve assembly with a bioabsorbable gasket and a replaceable valve implant
US9883941B2 (en) 2012-06-19 2018-02-06 Boston Scientific Scimed, Inc. Replacement heart valve
US9757536B2 (en) * 2012-07-17 2017-09-12 Novartis Ag Soft tip cannula
US20140100426A1 (en) * 2012-08-03 2014-04-10 Ipsyrng Capital Development, Llc Blunt tip cannula for injection of a material into a patient
US10052227B2 (en) * 2012-09-18 2018-08-21 Liviu B. Saimovici Cataract removal device and integrated tip
US10624784B2 (en) 2012-09-18 2020-04-21 Liviu B. Saimovici Cataract removal device and integrated tip
EP2719423B1 (en) 2012-10-12 2015-02-18 Sorin CRM SAS Atraumatic detection/stimulation microprobe
US9693821B2 (en) 2013-03-11 2017-07-04 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
EP2967734B1 (en) 2013-03-15 2019-05-15 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9297845B2 (en) 2013-03-15 2016-03-29 Boston Scientific Scimed, Inc. Medical devices and methods for treatment of hypertension that utilize impedance compensation
RU2667184C2 (en) 2013-06-06 2018-09-17 Новартис Аг Transformer irrigation/aspiration device
US9289575B2 (en) 2013-06-20 2016-03-22 Philip J. Dye Catheter
US9878125B2 (en) 2013-06-20 2018-01-30 Zcath Llc Intermittent urinary catheter
US9486603B2 (en) 2013-06-20 2016-11-08 Philip J. Dye Intermittent urinary catheter
EP3010437A1 (en) 2013-06-21 2016-04-27 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
CN105473092B (en) 2013-06-21 2019-05-17 波士顿科学国际有限公司 The medical instrument for renal nerve ablation with rotatable shaft
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
WO2015002787A1 (en) 2013-07-01 2015-01-08 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
WO2015006480A1 (en) 2013-07-11 2015-01-15 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
EP3019106A1 (en) 2013-07-11 2016-05-18 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
US9561103B2 (en) 2013-07-17 2017-02-07 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
WO2015010074A1 (en) 2013-07-19 2015-01-22 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
WO2015013205A1 (en) 2013-07-22 2015-01-29 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10695124B2 (en) 2013-07-22 2020-06-30 Boston Scientific Scimed, Inc. Renal nerve ablation catheter having twist balloon
ES2666373T3 (en) * 2013-08-16 2018-05-04 Cardiac Pacemakers, Inc. Management devices for wireless heart devices
WO2015027096A1 (en) 2013-08-22 2015-02-26 Boston Scientific Scimed, Inc. Flexible circuit having improved adhesion to a renal nerve modulation balloon
JP6563394B2 (en) 2013-08-30 2019-08-21 イェーナヴァルヴ テクノロジー インコーポレイテッド Radially foldable frame for an artificial valve and method for manufacturing the frame
EP3041425B1 (en) 2013-09-04 2022-04-13 Boston Scientific Scimed, Inc. Radio frequency (rf) balloon catheter having flushing and cooling capability
WO2015038947A1 (en) 2013-09-13 2015-03-19 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
US9891296B2 (en) 2013-09-13 2018-02-13 MRI Interventions, Inc. Intrabody fluid transfer devices, systems and methods
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
CN105592778B (en) 2013-10-14 2019-07-23 波士顿科学医学有限公司 High-resolution cardiac mapping electrod-array conduit
AU2014334574B2 (en) 2013-10-15 2017-07-06 Boston Scientific Scimed, Inc. Medical device balloon
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
CN105636538B (en) 2013-10-18 2019-01-15 波士顿科学国际有限公司 Foley's tube with flexible wire and its correlation technique for using and manufacturing
US20150112356A1 (en) * 2013-10-23 2015-04-23 Novartis Ag Hybrid phacoemulsification needle
CN105658163B (en) 2013-10-25 2020-08-18 波士顿科学国际有限公司 Embedded thermocouple in denervation flexible circuit
WO2015103617A1 (en) 2014-01-06 2015-07-09 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
WO2015107506A2 (en) 2014-01-20 2015-07-23 Baylis Medical Company Inc. Collapsible tip re-entry catheter
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
JP6325121B2 (en) 2014-02-04 2018-05-16 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Alternative placement of temperature sensors on bipolar electrodes
US10709490B2 (en) 2014-05-07 2020-07-14 Medtronic Ardian Luxembourg S.A.R.L. Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods
US10092742B2 (en) 2014-09-22 2018-10-09 Ekos Corporation Catheter system
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
WO2016093877A1 (en) 2014-12-09 2016-06-16 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
US10449043B2 (en) 2015-01-16 2019-10-22 Boston Scientific Scimed, Inc. Displacement based lock and release mechanism
US10918829B2 (en) 2015-01-22 2021-02-16 Boston Scientific Scimed, Inc. Fully compliant large bore expandable sheath
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US10201417B2 (en) 2015-02-03 2019-02-12 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10285809B2 (en) 2015-03-06 2019-05-14 Boston Scientific Scimed Inc. TAVI anchoring assist device
US10426617B2 (en) 2015-03-06 2019-10-01 Boston Scientific Scimed, Inc. Low profile valve locking mechanism and commissure assembly
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
JP6767388B2 (en) 2015-05-01 2020-10-14 イェーナヴァルヴ テクノロジー インコーポレイテッド Devices and methods to reduce the proportion of pacemakers in heart valve replacement
WO2016183523A1 (en) 2015-05-14 2016-11-17 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
EP3294221B1 (en) 2015-05-14 2024-03-06 Cephea Valve Technologies, Inc. Replacement mitral valves
US10656025B2 (en) 2015-06-10 2020-05-19 Ekos Corporation Ultrasound catheter
US10335277B2 (en) 2015-07-02 2019-07-02 Boston Scientific Scimed Inc. Adjustable nosecone
US10195392B2 (en) 2015-07-02 2019-02-05 Boston Scientific Scimed, Inc. Clip-on catheter
US10136991B2 (en) 2015-08-12 2018-11-27 Boston Scientific Scimed Inc. Replacement heart valve implant
US10179041B2 (en) 2015-08-12 2019-01-15 Boston Scientific Scimed Icn. Pinless release mechanism
US10342660B2 (en) 2016-02-02 2019-07-09 Boston Scientific Inc. Tensioned sheathing aids
WO2017142698A1 (en) 2016-02-17 2017-08-24 MRI Interventions, Inc. Intrabody surgical fluid transfer assemblies with adjustable exposed cannula to needle tip length, related systems and methods
US10583005B2 (en) 2016-05-13 2020-03-10 Boston Scientific Scimed, Inc. Medical device handle
EP4183371A1 (en) 2016-05-13 2023-05-24 JenaValve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
US10201416B2 (en) 2016-05-16 2019-02-12 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US11331187B2 (en) 2016-06-17 2022-05-17 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
CA3051272C (en) 2017-01-23 2023-08-22 Cephea Valve Technologies, Inc. Replacement mitral valves
AU2018203053B2 (en) 2017-01-23 2020-03-05 Cephea Valve Technologies, Inc. Replacement mitral valves
WO2018138658A1 (en) 2017-01-27 2018-08-02 Jenavalve Technology, Inc. Heart valve mimicry
WO2018213222A1 (en) 2017-05-15 2018-11-22 Boston Scientific Scimed, Inc. Radially expandable introducer sheath
US10828154B2 (en) 2017-06-08 2020-11-10 Boston Scientific Scimed, Inc. Heart valve implant commissure support structure
EP3655053A4 (en) * 2017-07-21 2021-06-16 The Alfred E. Mann Foundation for Scientific Research Catheters including radiopaque markers and methods of making the same
WO2019028161A1 (en) 2017-08-01 2019-02-07 Boston Scientific Scimed, Inc. Medical implant locking mechanism
US10939996B2 (en) 2017-08-16 2021-03-09 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
WO2019144071A1 (en) 2018-01-19 2019-07-25 Boston Scientific Scimed, Inc. Medical device delivery system with feedback loop
WO2019144069A2 (en) 2018-01-19 2019-07-25 Boston Scientific Scimed, Inc. Inductance mode deployment sensors for transcatheter valve system
US11147668B2 (en) 2018-02-07 2021-10-19 Boston Scientific Scimed, Inc. Medical device delivery system with alignment feature
US11129959B2 (en) 2018-02-15 2021-09-28 Boston Scientific Scimed, Inc. Introducer with expandable capabilities
US11439732B2 (en) 2018-02-26 2022-09-13 Boston Scientific Scimed, Inc. Embedded radiopaque marker in adaptive seal
US11883003B2 (en) 2018-03-26 2024-01-30 Gyrus Acmi, Inc. D/B/A Olympus Surgical Technologies America Compliant, atraumatic sheath tips
US11253237B2 (en) 2018-05-09 2022-02-22 Clearpoint Neuro, Inc. MRI compatible intrabody fluid transfer systems and related devices and methods
US11022664B2 (en) 2018-05-09 2021-06-01 Clearpoint Neuro, Inc. MRI compatible intrabody fluid transfer systems and related devices and methods
US11229517B2 (en) 2018-05-15 2022-01-25 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
WO2019241477A1 (en) 2018-06-13 2019-12-19 Boston Scientific Scimed, Inc. Replacement heart valve delivery device
JP7267401B2 (en) 2018-09-10 2023-05-01 ボストン サイエンティフィック サイムド，インコーポレイテッド Introducer with extensible properties
US11241312B2 (en) 2018-12-10 2022-02-08 Boston Scientific Scimed, Inc. Medical device delivery system including a resistance member
US11452533B2 (en) 2019-01-10 2022-09-27 Abbott Cardiovascular Systems Inc. Guide wire tip having roughened surface
US11730358B2 (en) * 2019-02-15 2023-08-22 California Institute Of Technology Tear flow measurement device
US11439504B2 (en) 2019-05-10 2022-09-13 Boston Scientific Scimed, Inc. Replacement heart valve with improved cusp washout and reduced loading
US11684750B2 (en) 2019-10-08 2023-06-27 Clearpoint Neuro, Inc. Extension tube assembly and related medical fluid transfer systems and methods

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3433226A (en) * 1965-07-21 1969-03-18 Aeroprojects Inc Vibratory catheterization apparatus and method of using
US3592197A (en) * 1969-03-24 1971-07-13 Milton J Cohen Catheter
US3605750A (en) * 1969-04-07 1971-09-20 David S Sheridan X-ray tip catheter
US3635223A (en) * 1969-12-02 1972-01-18 Us Catheter & Instr Corp Embolectomy catheter
USRE30365E (en) * 1971-05-03 1980-08-12 Disposable catheter
JPS4862286A (en) * 1971-12-03 1973-08-30
US3866599A (en) * 1972-01-21 1975-02-18 Univ Washington Fiberoptic catheter
GB1428766A (en) * 1973-02-22 1976-03-17 Ogley W Catheter
NL7402746A (en) * 1973-03-08 1974-09-10
US3865666A (en) * 1973-05-08 1975-02-11 Int Paper Co Method of making a catheter
JPS5116997A (en) * 1974-08-01 1976-02-10 Ikegami Tsushinki Kk Fukusushuno shiheino bunruishikibetsuhoshiki
US4003369A (en) * 1975-04-22 1977-01-18 Medrad, Inc. Angiographic guidewire with safety core wire
US4213461A (en) * 1977-09-15 1980-07-22 Pevsner Paul H Miniature balloon catheter
US4160448A (en) * 1977-05-23 1979-07-10 Jackson Richard R Blood pressure measuring catheter
JPS6051913B2 (en) * 1977-11-04 1985-11-16 オリンパス光学工業株式会社 balloon catheter
CA1135140A (en) * 1978-03-07 1982-11-09 Kiyoshi Asai Catheter placement system
US4280500A (en) * 1978-03-31 1981-07-28 Kazuaki Ono Tubular flexible medical instrument
DE2818119A1 (en) * 1978-04-25 1979-11-08 Reinhold Grundke Bladder catheter - with double-walled end inflatable to funnel after insertion
US4207900A (en) * 1978-07-03 1980-06-17 The Kendall Company Insert molded catheter and method
JPS5550369A (en) * 1978-10-06 1980-04-12 Kuraray Co Balloon catheter
US4301803A (en) * 1978-10-06 1981-11-24 Kuraray Co., Ltd. Balloon catheter
US4350169A (en) * 1979-01-05 1982-09-21 Medtronic, Inc. Flexible tip stiffening stylet for use with body implantable lead
US4254774A (en) * 1979-02-14 1981-03-10 The United States Of America As Represented By The Department Of Health, Education And Welfare Balloon catheter and technique for the manufacture thereof
US4239042A (en) * 1979-04-05 1980-12-16 Dow Corning K.K. Catheter placement system
US4385635A (en) * 1980-04-25 1983-05-31 Ruiz Oscar F Angiographic catheter with soft tip end
US4419095A (en) * 1980-05-14 1983-12-06 Shiley, Inc. Cannula with radiopaque tip
JPS587263A (en) * 1981-07-03 1983-01-17 水上　公宏 Balloon for introduction of vessel
CA1191064A (en) * 1981-12-31 1985-07-30 Bard (C. R.), Inc. Catheter with selectively rigidified portion
US4446867A (en) * 1981-12-31 1984-05-08 Leveen Robert F Fluid-driven balloon catheter for intima fracture
US4665604A (en) * 1982-02-16 1987-05-19 Cordis Corporation Non-fused torque control catheter

Also Published As

Publication number Publication date
US4531943A (en) 1985-07-30
IT8349583A0 (en) 1983-12-27
GB2144635B (en) 1987-04-23
DK583083A (en) 1985-02-09
DE3341850A1 (en) 1985-02-28
FR2550454A1 (en) 1985-02-15
GB2144635A (en) 1985-03-13
IT1171896B (en) 1987-06-10
NL8303940A (en) 1985-03-01
JPS6040069A (en) 1985-03-02
DK166129C (en) 1993-08-09
FR2550454B1 (en) 1988-07-15
GB8330312D0 (en) 1983-12-21
NL187049C (en) 1991-05-16
DK166129B (en) 1993-03-15
DE3341850C2 (en) 1990-08-09
DK583083D0 (en) 1983-12-16
JPH0128588B2 (en) 1989-06-05

Similar Documents

Publication Publication Date Title
CA1207206A (en) Catheter having a soft, deformable tip
US5078685A (en) Catheter with exterior tunnel member
EP2233169B1 (en) Transseptal cannula device, coaxial balloon delivery device, and methods of using the same
US6217548B1 (en) Cardioplegia balloon cannula
US6139524A (en) Stent delivery system with perfusion
US5876374A (en) Catheter sleeve for use with a balloon catheter
US5487730A (en) Balloon catheter with balloon surface retention means
US4819751A (en) Valvuloplasty catheter and method
US5112304A (en) Balloon catheter
US5843027A (en) Balloon sheath
US5653690A (en) Catheter having a balloon with retention enhancement
US5820586A (en) Method for introducing cardioplegia solution into the coronary sinus
US5171297A (en) Balloon catheter
US6221063B1 (en) Method of administering cardioplegia solution
AU7270498A (en) Aortic arch occlusion and perfusion balloon catheter having pressure ports
EP0351734B1 (en) Balloon catheter
CA1104021A (en) Catheter
US6068608A (en) Method of using integral aortic arch infusion clamp
EP3797817A1 (en) Balloon devices
EP1051214A1 (en) Catheter having integral expandable/collapsible lumen

Legal Events

Date Code Title Description
MKEX Expiry