CA1216634A - Implantable device for the stimulation of bone growth - Google Patents
Implantable device for the stimulation of bone growthInfo
- Publication number
- CA1216634A CA1216634A CA000440248A CA440248A CA1216634A CA 1216634 A CA1216634 A CA 1216634A CA 000440248 A CA000440248 A CA 000440248A CA 440248 A CA440248 A CA 440248A CA 1216634 A CA1216634 A CA 1216634A
- Authority
- CA
- Canada
- Prior art keywords
- pickup coil
- cover
- electrode
- tissue
- strip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
Abstract
ABSTRACT OF THE DISCLOSURE
An implantable device for the stimulation of bone growth is described, the device having an elongated pickup coil arrange-ment that is provided with connectors for tissue electrodes. An extended and strip-like tissue electrode extends from the pickup coil arrangement and the connectors have a hole for a bone screw and a sleeve-like extension adapted to accommodate a Kirschner wire electrode.
An implantable device for the stimulation of bone growth is described, the device having an elongated pickup coil arrange-ment that is provided with connectors for tissue electrodes. An extended and strip-like tissue electrode extends from the pickup coil arrangement and the connectors have a hole for a bone screw and a sleeve-like extension adapted to accommodate a Kirschner wire electrode.
Description
The present invention relates to an implant able device for the stimulation of bone growth, generally of the type disclosed in German Patent Aye. In particular, the present invention relates to a device for healing bone damage by means of low frequency electric current which is venerated by means of induction and which is preferably of a frequency below 30 Ho.
The present invention provides an improved device of the type described above which is more versatile and more comfortable and in particular is suitable for healing major bone defects (e.g., diastases of up to 10 centimeters or more).
According to the present invention, there is provided an implant able device, for the stimulation of bone growth, having a pickup coil arrangement including a pickup coil and at least a first and a second connection therefore and an elongated cover having a peripheral surface and a pair of opposing end surfaces, of tissue-compatible material, surrounding the pickup coil; and first and second electrical conduction means establishing first and second tissue connections, wherein said first conduction means comprises a tissue electrode, including an extended, strip-like, planar tissue electrode element, coupled to and extending longitudinally along the cover, and projecting edgewise sub-staunchly perpendicular to said peripheral surface thereof, said tissue electrode being coupled to one of the connections of the pickup coil; said second conduction means comprises a-t least one connector device coupled to the other of the connections of -the pickup coil; and a flexible insulated wire is provided, inter-connecting each connector device and said other connection of I I
the pickup coil.
In -the present device bone screws and/or Kirchner wires and/or easily attachable strip-like electrodes ("keel electrodes") are used as electrodes according to choice. The electrode struck lure for the application of the low frequency alternating current I Jo that is induced by the low frequency electromagnetic field can thus be very well matched to any particular situation A preferred exemplary version of the invention is described below with reference to the accompanying drawings appended hereto, in which:
Figure 1 is a simplified schematic plan view of a device according to one exemplary version of the invention;
Figure 2 is a cross section taken on line I~-II ox Figure 1;
Figure 3 is a plan view of a strip-like electrode ("keel electrode that can be slid into position;
Figure 4 is a cross section taken on line IV-IV ox Figure 3;
Figure 5 is a perspective view of a device according to Figure 1 with the keel electrode positioned according to Figures 3 and 4 as well as with additional Kirchner wire electrodes;
Figure 6 is a perspective view of a preferred embodiment of the invention; and Figure 7 is a plan view of the underside of the device according to Figure 6.
Figures 1 to 5 show an implant able device which comprises: a solenoid-like pickup coil 10 having a magnetic core l2l that is shown in Figure 1 as a circuit diagram. The pickup coil 10 and the magnetic core 12 are surrounded by a cover lo made of a tissue compatible insulating material, e.g. polytetrafluoro-ethylene (PTFE). The pickup coil 10, core 12 and cover 14 form together a pickup coil arrangement designated by numeral 20 in Figure 1.
~6~,3~
The ends of tune pickup coil 10 are connected electric gaily in each instance with elongated contacts 16 and 18 respect lively, which are arranged with their surfaces lying freely on one side of the pickup coil arrangement 20 along the longitudinal axis of the pickup coil arrangement, as can be seen from Figure 1. The ends of the elongated contacts I and I are in each instance connected with two insulated connector wires 22 that in each instance lead to a connector device 24. The connector devices 24 consist of a tissue-compatible electrically conductive material, such as osteosynthesis metal, and comprise an elongated, plate-like portion 26 having a hole 28 for a bone screw. The area that surrounds the hole is dished, in order to accept the head of the screw, and in addition on the diametrically opposite sides of the hole 28 there are two tangentially parallel slots 30 provided so that bone screws of different thicknesses can be inserted. The connector devices 24 also have in each instance a lateral tab 32 which connects the portion 26 to a sleeve-like rolled part 34.
The sleeve-like part 34 is adapted to accommodate a ~irschner wire 36 shown in Figure 5.
The cover 14 is provided with lateral, pierced, tab-like portions 38 which enables the pickup coil arrangement 20 to be fixed in the implantation area by means of a wire or the like.
The contacts 16 and lo serve to provide respective elect tribal connections for electrode arrangements 40, one of which is shown in Figures 3 and 4. Each electrode arrangement 40 comprise a clamp-like part 42 that matches the cross sectional shape of the pickup coil arrangement 20 and a strip-like electrode 44. The electrode 44 is connected to the clamp-like part 42 by means of tab-like extensions 46 which may be spot welded into place. The electrode arrangements I can be slid in a longitudinal direction onto the pickup coil arrangement 20 in such a manner that the contacts 16 and 18, respectively, produce electrical connections between the pickup coil lo and the clamp-like portions 42 and the strip-like electrodes 44 ("keel electrodes"). When the electrode arrangements 40 are installed on the one side of the pickup coil arrangement 20, the strip-like electrodes 44 run axially with respect to the pickup coil arrangement and project beyond its ends as can be seen in Figure 5. The strip-like electrodes 44 form tissue electrodes which in the installed state extend in the main perpendicularly from the cover 14 and thus stand "on edge" on thy relevant part of the outside of the cover 14.
The cover 14 can be provided with peg-like extensions 48 where the insulated connector wires 22 emerge which will serve to prevent the wires from becoming kinked.
hen this device is used, it is implanted in the area of the bone damage that is to be repaired. Even major diastases can be bridged by means of the strip-like electrodes 44. According to need any number of connector devices 24 can be provided with bone screw electrodes and/or Kirchner electrodes. The tabs 32 consist of a relatively thin sheet of metal that can be very easily bent and twisted so that the inserted Kirchner wires 36 can be implanted and oriented as desired, as can be seen, for example, in the lower right hand part of Figure 5.
'rho strip-like electrodes 44 can be cut to any desired I
length. In addition, they can be bent should this be desired.
Insofar as the connector devices 24 are not needed, they can, together with the associated connector wire on the extensions 48, simply be cut off.
Because of the slots 30 the connector devices can be used for screws of various diameters, e.g., screws with diameters between 3.0 and 4.5 mm can be used. The sleeve-like part 34 normally has an internal diameter or approximately 2 mm, but since it is not closed, it can also accommodate thicker Kirchner wires.
The pickup coil 10 and the magnetic core 12 can be configured in any familiar manner. After implantation, a low frequency alter-noting current is induced in the pickup coil 10 in the above described device.
The pickup coil arrangement 20 can in practice have a cross section in the form of a flat rectangle having rounded corners, the longer side of which is approximately 12 mm and the shorter side of which is approximately 6 mm. The length of the pickup coil arrangement 20 without the connecting wires can amount to approximately 75 mm. The strip-like electrodes 44, which, as shown, stand preferably perpendicularly on the flat side of the pickup coil arrangement can be approximately 60 to 80 mm long, approximately 4 to 7 mm wide, and approximately 0.5 mm thick The electrode arrangements 40 consist preferably of a tissue Compaq title osteosynthesis metal, such as a conventional cobalt-chromium alloy.
Tune preferred embodiment or the implant able device according to the invention is shown schematically in Figures 6 and I
7 and comprises a pickup coil arrangement 120, which is in the main configured like the pickup coil arrangement 20 according to Figure 1. The pickup coil arrangement 720 comprises a pickup coil 110, a magnetic core l12 as well as a cover 114~ The cover is provided with securing tabs 13~ at its longitudinal ends. In this embodiment, all the connector devices 124 are connected by ins-fated wires 122 to the same connector owe. Connector oboe is connected permanently to a continuous and st~ip-like tissue elect trove 144 which in twirl is connected permanently to the pickup coil arrangement 12~ and extends in a longitudinal direction from the pickup coil arrangement 120. The electrode 114 stands on edge upon the pickup coil arrangement 120 and extends longitudinally beyond the ends of the pickup coil arrangement as can be seen particularly in Figure 7. Ike pickup coil arrangement 120 has a flattened underside aye, upon which there is an additional plate-like electrode 145, which is connected electrically and mechanic gaily with the keel-like tissue electrode 144 and which forms an additional contact surface on the cover of the underside of the pickup coil arrangement 120.
The keel-like tissue electrode 144 is mechanically and rigidly connected to the pickup coil arrangement 120 and the add-tonal plate-like electrode 145 thereby forming one electrode, and the connector device 124 with the electrodes which are attached to them, such as a Kirchner wire 36 or a bone screw (not shown) form the opposite pole. The strip-like electrode l44 can in practice be 120 mm long and when used can be cut to the length required to bridge a bone defect.
I
The embodiment shown in Figures 6 and 7 can be changed in that the electrode combination 144 and 145 can be divided transverse to the longitudinal direction of the arrangement 120 into two electrically separate parts, and each part would contain similar tissue electrodes which stand on edge as in Figure 5 and project beyond one end of the arrangement 120. The two parts of the electrode combination are then connected by means of different connectors to the pickup coil 110. The portion of the strip-like electrode 144 and the connector wire 122 for the connector device 124 which are located at the same axial end of the device 120 are then preferably connected to different connectors of the pickup coil.
The plate-like electrode 145 which forms the additional contact surface is preferably mechanically connected rigidly to the strip-like tissue electrode 144 and assists in anchoring electrode 144 to the arrangement 120.
The present invention provides an improved device of the type described above which is more versatile and more comfortable and in particular is suitable for healing major bone defects (e.g., diastases of up to 10 centimeters or more).
According to the present invention, there is provided an implant able device, for the stimulation of bone growth, having a pickup coil arrangement including a pickup coil and at least a first and a second connection therefore and an elongated cover having a peripheral surface and a pair of opposing end surfaces, of tissue-compatible material, surrounding the pickup coil; and first and second electrical conduction means establishing first and second tissue connections, wherein said first conduction means comprises a tissue electrode, including an extended, strip-like, planar tissue electrode element, coupled to and extending longitudinally along the cover, and projecting edgewise sub-staunchly perpendicular to said peripheral surface thereof, said tissue electrode being coupled to one of the connections of the pickup coil; said second conduction means comprises a-t least one connector device coupled to the other of the connections of -the pickup coil; and a flexible insulated wire is provided, inter-connecting each connector device and said other connection of I I
the pickup coil.
In -the present device bone screws and/or Kirchner wires and/or easily attachable strip-like electrodes ("keel electrodes") are used as electrodes according to choice. The electrode struck lure for the application of the low frequency alternating current I Jo that is induced by the low frequency electromagnetic field can thus be very well matched to any particular situation A preferred exemplary version of the invention is described below with reference to the accompanying drawings appended hereto, in which:
Figure 1 is a simplified schematic plan view of a device according to one exemplary version of the invention;
Figure 2 is a cross section taken on line I~-II ox Figure 1;
Figure 3 is a plan view of a strip-like electrode ("keel electrode that can be slid into position;
Figure 4 is a cross section taken on line IV-IV ox Figure 3;
Figure 5 is a perspective view of a device according to Figure 1 with the keel electrode positioned according to Figures 3 and 4 as well as with additional Kirchner wire electrodes;
Figure 6 is a perspective view of a preferred embodiment of the invention; and Figure 7 is a plan view of the underside of the device according to Figure 6.
Figures 1 to 5 show an implant able device which comprises: a solenoid-like pickup coil 10 having a magnetic core l2l that is shown in Figure 1 as a circuit diagram. The pickup coil 10 and the magnetic core 12 are surrounded by a cover lo made of a tissue compatible insulating material, e.g. polytetrafluoro-ethylene (PTFE). The pickup coil 10, core 12 and cover 14 form together a pickup coil arrangement designated by numeral 20 in Figure 1.
~6~,3~
The ends of tune pickup coil 10 are connected electric gaily in each instance with elongated contacts 16 and 18 respect lively, which are arranged with their surfaces lying freely on one side of the pickup coil arrangement 20 along the longitudinal axis of the pickup coil arrangement, as can be seen from Figure 1. The ends of the elongated contacts I and I are in each instance connected with two insulated connector wires 22 that in each instance lead to a connector device 24. The connector devices 24 consist of a tissue-compatible electrically conductive material, such as osteosynthesis metal, and comprise an elongated, plate-like portion 26 having a hole 28 for a bone screw. The area that surrounds the hole is dished, in order to accept the head of the screw, and in addition on the diametrically opposite sides of the hole 28 there are two tangentially parallel slots 30 provided so that bone screws of different thicknesses can be inserted. The connector devices 24 also have in each instance a lateral tab 32 which connects the portion 26 to a sleeve-like rolled part 34.
The sleeve-like part 34 is adapted to accommodate a ~irschner wire 36 shown in Figure 5.
The cover 14 is provided with lateral, pierced, tab-like portions 38 which enables the pickup coil arrangement 20 to be fixed in the implantation area by means of a wire or the like.
The contacts 16 and lo serve to provide respective elect tribal connections for electrode arrangements 40, one of which is shown in Figures 3 and 4. Each electrode arrangement 40 comprise a clamp-like part 42 that matches the cross sectional shape of the pickup coil arrangement 20 and a strip-like electrode 44. The electrode 44 is connected to the clamp-like part 42 by means of tab-like extensions 46 which may be spot welded into place. The electrode arrangements I can be slid in a longitudinal direction onto the pickup coil arrangement 20 in such a manner that the contacts 16 and 18, respectively, produce electrical connections between the pickup coil lo and the clamp-like portions 42 and the strip-like electrodes 44 ("keel electrodes"). When the electrode arrangements 40 are installed on the one side of the pickup coil arrangement 20, the strip-like electrodes 44 run axially with respect to the pickup coil arrangement and project beyond its ends as can be seen in Figure 5. The strip-like electrodes 44 form tissue electrodes which in the installed state extend in the main perpendicularly from the cover 14 and thus stand "on edge" on thy relevant part of the outside of the cover 14.
The cover 14 can be provided with peg-like extensions 48 where the insulated connector wires 22 emerge which will serve to prevent the wires from becoming kinked.
hen this device is used, it is implanted in the area of the bone damage that is to be repaired. Even major diastases can be bridged by means of the strip-like electrodes 44. According to need any number of connector devices 24 can be provided with bone screw electrodes and/or Kirchner electrodes. The tabs 32 consist of a relatively thin sheet of metal that can be very easily bent and twisted so that the inserted Kirchner wires 36 can be implanted and oriented as desired, as can be seen, for example, in the lower right hand part of Figure 5.
'rho strip-like electrodes 44 can be cut to any desired I
length. In addition, they can be bent should this be desired.
Insofar as the connector devices 24 are not needed, they can, together with the associated connector wire on the extensions 48, simply be cut off.
Because of the slots 30 the connector devices can be used for screws of various diameters, e.g., screws with diameters between 3.0 and 4.5 mm can be used. The sleeve-like part 34 normally has an internal diameter or approximately 2 mm, but since it is not closed, it can also accommodate thicker Kirchner wires.
The pickup coil 10 and the magnetic core 12 can be configured in any familiar manner. After implantation, a low frequency alter-noting current is induced in the pickup coil 10 in the above described device.
The pickup coil arrangement 20 can in practice have a cross section in the form of a flat rectangle having rounded corners, the longer side of which is approximately 12 mm and the shorter side of which is approximately 6 mm. The length of the pickup coil arrangement 20 without the connecting wires can amount to approximately 75 mm. The strip-like electrodes 44, which, as shown, stand preferably perpendicularly on the flat side of the pickup coil arrangement can be approximately 60 to 80 mm long, approximately 4 to 7 mm wide, and approximately 0.5 mm thick The electrode arrangements 40 consist preferably of a tissue Compaq title osteosynthesis metal, such as a conventional cobalt-chromium alloy.
Tune preferred embodiment or the implant able device according to the invention is shown schematically in Figures 6 and I
7 and comprises a pickup coil arrangement 120, which is in the main configured like the pickup coil arrangement 20 according to Figure 1. The pickup coil arrangement 720 comprises a pickup coil 110, a magnetic core l12 as well as a cover 114~ The cover is provided with securing tabs 13~ at its longitudinal ends. In this embodiment, all the connector devices 124 are connected by ins-fated wires 122 to the same connector owe. Connector oboe is connected permanently to a continuous and st~ip-like tissue elect trove 144 which in twirl is connected permanently to the pickup coil arrangement 12~ and extends in a longitudinal direction from the pickup coil arrangement 120. The electrode 114 stands on edge upon the pickup coil arrangement 120 and extends longitudinally beyond the ends of the pickup coil arrangement as can be seen particularly in Figure 7. Ike pickup coil arrangement 120 has a flattened underside aye, upon which there is an additional plate-like electrode 145, which is connected electrically and mechanic gaily with the keel-like tissue electrode 144 and which forms an additional contact surface on the cover of the underside of the pickup coil arrangement 120.
The keel-like tissue electrode 144 is mechanically and rigidly connected to the pickup coil arrangement 120 and the add-tonal plate-like electrode 145 thereby forming one electrode, and the connector device 124 with the electrodes which are attached to them, such as a Kirchner wire 36 or a bone screw (not shown) form the opposite pole. The strip-like electrode l44 can in practice be 120 mm long and when used can be cut to the length required to bridge a bone defect.
I
The embodiment shown in Figures 6 and 7 can be changed in that the electrode combination 144 and 145 can be divided transverse to the longitudinal direction of the arrangement 120 into two electrically separate parts, and each part would contain similar tissue electrodes which stand on edge as in Figure 5 and project beyond one end of the arrangement 120. The two parts of the electrode combination are then connected by means of different connectors to the pickup coil 110. The portion of the strip-like electrode 144 and the connector wire 122 for the connector device 124 which are located at the same axial end of the device 120 are then preferably connected to different connectors of the pickup coil.
The plate-like electrode 145 which forms the additional contact surface is preferably mechanically connected rigidly to the strip-like tissue electrode 144 and assists in anchoring electrode 144 to the arrangement 120.
Claims (6)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. An implantable device, for the stimulation of bone growth, having a pickup coil arrangement including a pickup coil and at least a first and a second connection therefor, and an elongated cover having a peripheral surface and a pair of opposing end surfaces, of tissue-compatible material, surrounding the pickup coil; and first and second electrical conduction means establishing first and second tissue connections, wherein said first conduction means comprises a tissue electrode, including an extended, strip-like, planar tissue electrode element, coupled to and extending longitudinally along the cover, and projecting edgewise substantially perpendicular to said peripheral surface thereof, said tissue electrode being coupled to one of the connections of the pickup coil; said second conduc-tion means comprises at least one connector device coupled to the other of the connections of the pickup coil; and a flexible insulated wire is provided, interconnecting each connector device and said other connection of the pickup coil.
2. A device according to claim 1, characterized in that the extended tissue electrode extends beyond the longitudinal ends of the cover.
3. A device according to claim 1, in which the cover is approximately in the form of a flat rectangle and the plane of the strip-like tissue electrode extends perpendicularly to the larger side of the rectangle.
4. A device according to claim 3, in which the extended tissue electrode extends beyond the longitudinal ends of the cover.
5. A device according to claim 1, including a plate-shaped electrode formed on the surface of the cover, the strip-like electrode element projecting from said plate-shaped electrode and being electrically connected thereto.
6. A device according to claim 1, in which said one of the connections of the pickup coil forms a terminal which lies exposed and is positioned on one side of the cover; and the tissue electrode is shaped to match the circumference of the cover so that it can be slid over said cover and includes a first electrically conducting part which, when the electrode is slid into position over the cover, engages said terminal, the tissue electrode element being electrically and mechanically connected to said first electrically conducting part.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP3240592.8 | 1982-11-03 | ||
| DE19823240592 DE3240592A1 (en) | 1982-11-03 | 1982-11-03 | IMPLANTABLE DEVICE FOR STIMULATING BONE GROWTH |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1216634A true CA1216634A (en) | 1987-01-13 |
Family
ID=6177202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000440248A Expired CA1216634A (en) | 1982-11-03 | 1983-11-02 | Implantable device for the stimulation of bone growth |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4611597A (en) |
| EP (1) | EP0108383B1 (en) |
| JP (1) | JPS5997653A (en) |
| AT (1) | ATE49893T1 (en) |
| CA (1) | CA1216634A (en) |
| DE (2) | DE3240592A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11305112B2 (en) | 2018-05-16 | 2022-04-19 | DePuy Synthes Products, Inc. | Electrical stimulation implants |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3414514A1 (en) * | 1984-04-13 | 1985-10-24 | Biotronik Meß- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin, 1000 Berlin | SCREW-IN PAN FOR AN ARTIFICIAL HIP JOINT |
| EP0227754A4 (en) * | 1985-06-20 | 1987-11-10 | Noel Desmond Gray | Internally applied self energising healing electrodes. |
| JP2614838B2 (en) * | 1988-09-17 | 1997-05-28 | 竹本油脂株式会社 | Graft copolymers useful as unsaturated polyester resin additives |
| US5193540A (en) * | 1991-12-18 | 1993-03-16 | Alfred E. Mann Foundation For Scientific Research | Structure and method of manufacture of an implantable microstimulator |
| US5193539A (en) * | 1991-12-18 | 1993-03-16 | Alfred E. Mann Foundation For Scientific Research | Implantable microstimulator |
| EP0561068B1 (en) * | 1992-02-20 | 1999-03-03 | Neomedics, Inc. | Implantable bone growth stimulator |
| US5565005A (en) * | 1992-02-20 | 1996-10-15 | Amei Technologies Inc. | Implantable growth tissue stimulator and method operation |
| US5524624A (en) * | 1994-05-05 | 1996-06-11 | Amei Technologies Inc. | Apparatus and method for stimulating tissue growth with ultrasound |
| ATE306213T1 (en) | 1998-12-23 | 2005-10-15 | Nuvasive Inc | DEVICES FOR CANNULATION AND NERVE MONITORING |
| CA2363254C (en) | 1999-03-07 | 2009-05-05 | Discure Ltd. | Method and apparatus for computerized surgery |
| KR20020077346A (en) | 1999-11-24 | 2002-10-11 | 너바시브 인코퍼레이티드 | Electromyography system |
| EP1417000B1 (en) | 2001-07-11 | 2018-07-11 | Nuvasive, Inc. | System for determining nerve proximity during surgery |
| EP2481338A3 (en) | 2001-09-25 | 2012-09-05 | Nuvasive, Inc. | System for performing surgical procedures and assessments |
| US8147421B2 (en) | 2003-01-15 | 2012-04-03 | Nuvasive, Inc. | System and methods for determining nerve direction to a surgical instrument |
| US7582058B1 (en) | 2002-06-26 | 2009-09-01 | Nuvasive, Inc. | Surgical access system and related methods |
| US8137284B2 (en) | 2002-10-08 | 2012-03-20 | Nuvasive, Inc. | Surgical access system and related methods |
| US7691057B2 (en) * | 2003-01-16 | 2010-04-06 | Nuvasive, Inc. | Surgical access system and related methods |
| US7819801B2 (en) | 2003-02-27 | 2010-10-26 | Nuvasive, Inc. | Surgical access system and related methods |
| US20040243207A1 (en) * | 2003-05-30 | 2004-12-02 | Olson Donald R. | Medical implant systems |
| JP4463819B2 (en) | 2003-09-25 | 2010-05-19 | ヌヴァシヴ インコーポレイテッド | Surgical access system |
| US7905840B2 (en) | 2003-10-17 | 2011-03-15 | Nuvasive, Inc. | Surgical access system and related methods |
| US8313430B1 (en) | 2006-01-11 | 2012-11-20 | Nuvasive, Inc. | Surgical access system and related methods |
| EP1765204B1 (en) | 2004-06-07 | 2018-12-26 | Synthes GmbH | Orthopaedic implant with sensors |
| WO2006042241A2 (en) | 2004-10-08 | 2006-04-20 | Nuvasive, Inc. | Surgical access system and related methods |
| US9307925B2 (en) | 2005-06-16 | 2016-04-12 | Aaken Laboratories | Methods and systems for generating electrical property maps of biological structures |
| US8328851B2 (en) | 2005-07-28 | 2012-12-11 | Nuvasive, Inc. | Total disc replacement system and related methods |
| CA2750917A1 (en) | 2008-12-26 | 2010-07-01 | Scott Spann | Minimally-invasive retroperitoneal lateral approach for spinal surgery |
| US8287597B1 (en) | 2009-04-16 | 2012-10-16 | Nuvasive, Inc. | Method and apparatus for performing spine surgery |
| US9351845B1 (en) | 2009-04-16 | 2016-05-31 | Nuvasive, Inc. | Method and apparatus for performing spine surgery |
| CN102481451B (en) * | 2009-06-30 | 2014-10-15 | 比亚内·盖根斯 | Polarization device and implantation device |
| CN102210903A (en) * | 2010-04-02 | 2011-10-12 | 鼎迈医疗科技(苏州)有限公司 | Extension wire protective sleeve of implanted nerve electrical stimulation system |
| US8790406B1 (en) | 2011-04-01 | 2014-07-29 | William D. Smith | Systems and methods for performing spine surgery |
| CA2845332A1 (en) | 2011-08-19 | 2013-02-28 | Hunt Spine, Llc | Surgical retractor system and methods of use |
| US9198765B1 (en) | 2011-10-31 | 2015-12-01 | Nuvasive, Inc. | Expandable spinal fusion implants and related methods |
| KR20240005209A (en) | 2014-12-09 | 2024-01-11 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | Novel wound healing enhancing devices |
| CN104941065B (en) * | 2015-06-30 | 2018-02-27 | 北京品驰医疗设备有限公司 | Implantable neural electrical stimulator and the protective case applied to the implantable neural electrical stimulator |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1918299B2 (en) * | 1969-04-10 | 1972-04-13 | Kraus, Werner, Dipl.-Ing., 8000 München | Splint for guiding and healing fractured bones |
| AT316729B (en) * | 1971-04-06 | 1974-07-25 | Kraus Werner | Device to support the formation of bone substance |
| DE2311817C2 (en) * | 1973-03-09 | 1984-06-07 | Werner Dipl.-Ing. 8000 München Kraus | Stimulation current device to promote the healing of bone damage |
| SE374176C (en) * | 1973-07-09 | 1982-09-14 | Partner Ab | CENTRIFUGAL CLUTCH DISCONNECTING DEVICE |
| US3968790A (en) * | 1975-02-26 | 1976-07-13 | Rikagaku Kenkyusho | Electret method of promoting callus formation in regeneration of bones |
| JPS5311799A (en) * | 1976-07-19 | 1978-02-02 | Yutaka Ogawa | Machine for descaling fish |
| DE2636818A1 (en) * | 1976-08-16 | 1978-02-23 | Kraus Werner | Bone marrow pin contg. pick=up coil - with electrodes applied to and insulated from body outer surface |
| AT363171B (en) * | 1977-09-22 | 1981-07-10 | Kraus Werner | ADDITIONAL DEVICE FOR CONVERTING A CONVENTIONAL OSTEOSYNTHESIS IMPLANT INTO AN ELECTRO-OSTEOSYNTHESIS IMPLANT |
| DE2742741A1 (en) * | 1977-09-22 | 1979-04-05 | Kraus Werner | ADDITIONAL DEVICE FOR ATTACHING A PICKUP COIL AND ELECTRODE CONNECTORS TO AN OSTEOSYNTHESIS IMPLANT |
| JPS5645623A (en) * | 1979-09-25 | 1981-04-25 | Hitachi Ltd | Electric cleaner |
| DE3132488A1 (en) * | 1981-08-17 | 1983-02-24 | Werner Dipl.-Ing. 8000 München Kraus | Device for stimulating bone growth for an osteosynthesis implant |
-
1982
- 1982-11-03 DE DE19823240592 patent/DE3240592A1/en not_active Ceased
-
1983
- 1983-11-02 DE DE8383110916T patent/DE3381167D1/en not_active Expired - Lifetime
- 1983-11-02 CA CA000440248A patent/CA1216634A/en not_active Expired
- 1983-11-02 EP EP83110916A patent/EP0108383B1/en not_active Expired - Lifetime
- 1983-11-02 JP JP58206857A patent/JPS5997653A/en active Granted
- 1983-11-02 US US06/547,950 patent/US4611597A/en not_active Expired - Fee Related
- 1983-11-02 AT AT83110916T patent/ATE49893T1/en not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11305112B2 (en) | 2018-05-16 | 2022-04-19 | DePuy Synthes Products, Inc. | Electrical stimulation implants |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3381167D1 (en) | 1990-03-08 |
| JPH0454461B2 (en) | 1992-08-31 |
| EP0108383A2 (en) | 1984-05-16 |
| ATE49893T1 (en) | 1990-02-15 |
| EP0108383B1 (en) | 1990-01-31 |
| US4611597A (en) | 1986-09-16 |
| EP0108383A3 (en) | 1987-03-04 |
| DE3240592A1 (en) | 1984-05-03 |
| JPS5997653A (en) | 1984-06-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA1216634A (en) | Implantable device for the stimulation of bone growth | |
| US4421115A (en) | Electrification attachment for an osteosynthesis implantate | |
| WO2003039647A3 (en) | Optional use of a lead for a unitary subcutaneous implantable cardioverter-defibrillator | |
| JPH0318471B2 (en) | ||
| CA2164366A1 (en) | Electrical Connector | |
| US20020138101A1 (en) | Lead wire attachment method, electrode, and spot welder | |
| JPH03266383A (en) | High frequency connector and manufacture thereof | |
| CA2622411C (en) | A foil winding pulse transformer | |
| EP0692843A2 (en) | Connector terminal with insulation grip blade | |
| US3768062A (en) | Terminal for flexible circuits | |
| EP1405321A1 (en) | Transformer | |
| US20040078062A1 (en) | Header for implantable medical device | |
| US4490004A (en) | Connector for connecting insulated wires to a circuit board | |
| DE2636818A1 (en) | Bone marrow pin contg. pick=up coil - with electrodes applied to and insulated from body outer surface | |
| CN115501487A (en) | Telescopic electrode device | |
| US3824519A (en) | Coil forms and terminal | |
| ATE323529T1 (en) | DEVICE FOR HYPERTHERMIA TREATMENT | |
| ATE93990T1 (en) | COIL FOR ELECTRICAL COILS. | |
| US4466681A (en) | Soldering lug for mounting electrical conducting wires | |
| KR20030016181A (en) | Coupling adjustment structure for a double tunning circuit | |
| CN219477006U (en) | Connection structure of implantable pulse generator and implantable pulse generator | |
| EP0659098B1 (en) | Implant for electrostimulation of tissues | |
| EP0761075A1 (en) | Printed circuit board socket | |
| DE29824519U1 (en) | Ballast for electric lamps | |
| KR200160150Y1 (en) | Terminal board of one body type reduce coil structure of deflection yoke |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |