CA2001969A1 - Polysiloxane-polyurethanes and contact lenses thereof - Google Patents

Polysiloxane-polyurethanes and contact lenses thereof

Info

Publication number
CA2001969A1
CA2001969A1 CA2001969A CA2001969A CA2001969A1 CA 2001969 A1 CA2001969 A1 CA 2001969A1 CA 2001969 A CA2001969 A CA 2001969A CA 2001969 A CA2001969 A CA 2001969A CA 2001969 A1 CA2001969 A1 CA 2001969A1
Authority
CA
Canada
Prior art keywords
polysiloxane
contact lenses
polyurethanes
oxygen permeable
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2001969A
Other languages
French (fr)
Other versions
CA2001969C (en
Inventor
Paul Harisiades
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Huntsman Advanced Materials Switzerland GmbH
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of CA2001969A1 publication Critical patent/CA2001969A1/en
Application granted granted Critical
Publication of CA2001969C publication Critical patent/CA2001969C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/61—Polysiloxanes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses

Abstract

A novel polysiloxane polyurethane is described which is obtained by reaction of an isocyanate capped polysiloxane prepolymer with a polysiloxane-disilanol and which contains O-silyl-urethane linkages. The novel polysiloxane-poly-urethanes are useful as oxygen permeable membranes or films, as bandages and drug carriers, for example in transdermal drug delivery, and especially as highly oxygen permeable, soft contact lenses.
CA002001969A 1988-11-03 1989-11-01 Polysiloxane-polyurethanes and contact lenses thereof Expired - Fee Related CA2001969C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US266,555 1988-11-03
US07/266,555 US4962178A (en) 1988-11-03 1988-11-03 Novel polysiloxane-polyurethanes and contact lens thereof

Publications (2)

Publication Number Publication Date
CA2001969A1 true CA2001969A1 (en) 1990-05-03
CA2001969C CA2001969C (en) 2000-05-30

Family

ID=23015064

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002001969A Expired - Fee Related CA2001969C (en) 1988-11-03 1989-11-01 Polysiloxane-polyurethanes and contact lenses thereof

Country Status (13)

Country Link
US (1) US4962178A (en)
EP (1) EP0367720B1 (en)
JP (1) JP2845998B2 (en)
AT (1) ATE108809T1 (en)
AU (1) AU629252B2 (en)
CA (1) CA2001969C (en)
DE (1) DE68916907T2 (en)
DK (1) DK547189A (en)
ES (1) ES2057173T3 (en)
HK (1) HK9297A (en)
IE (1) IE63682B1 (en)
PT (1) PT92162B (en)
TW (1) TW205557B (en)

Families Citing this family (35)

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DE4008259A1 (en) * 1990-03-15 1991-09-19 Bayer Ag SILOXANE MODIFIED THERMOPLASTIC POLYURETHANE
US5204402A (en) * 1990-12-11 1993-04-20 Union Carbide Chemicals & Plastics Technology Corporation Multipurpose additive system for thermoplastic resins
DE4213217C2 (en) * 1992-04-22 1999-11-25 Geesthacht Gkss Forschung Membrane based on graft copolymers, graft copolymene and process for their production
GB9210653D0 (en) * 1992-05-19 1992-07-01 Ici Plc Silane functional oligomer
FR2708199B1 (en) * 1993-07-28 1995-09-01 Oreal New cosmetic compositions and uses.
US7468398B2 (en) 1994-09-06 2008-12-23 Ciba Vision Corporation Extended wear ophthalmic lens
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
SI0819258T1 (en) * 1995-04-04 2002-04-30 Novartis Ag Extended wear ophthalmic lens
US5574122A (en) * 1995-09-29 1996-11-12 Bayer Corporation Low surface energy polyisocyanates and their use in one- or two-component coating compositions
JP2000506554A (en) 1995-12-22 2000-05-30 ノバルティス アクチエンゲゼルシャフト Polyurethanes made from polysiloxane / polyol macromers
FR2743297B1 (en) * 1996-01-05 1998-03-13 Oreal COSMETIC COMPOSITION BASED ON MULTISEQUENCE IONIZABLE POLYCONDENSATES POLYSILOXANE / POLYURETHANE AND / OR POLYUREE IN SOLUTION AND USE
US5919441A (en) * 1996-04-01 1999-07-06 Colgate-Palmolive Company Cosmetic composition containing thickening agent of siloxane polymer with hydrogen-bonding groups
JP2002512187A (en) * 1998-04-17 2002-04-23 バーテック ファーマシューティカルズ，インコーポレイティド Topical preparations for the treatment of onychomycosis
US5969076A (en) * 1998-05-15 1999-10-19 Bausch & Lomb Incorporated Thermoplastic silicone-containing hydrogels
US6008317A (en) 1998-05-15 1999-12-28 Bausch & Lomb Incorporated Hydroxy or amino terminated hydrophilic polymers
US6218503B1 (en) 1998-05-15 2001-04-17 Bausch & Lomb Incorporated Silicone-containing prepolymers
US6277364B1 (en) 1998-10-09 2001-08-21 Bertek Pharmaceuticals, Inc. Polyurethanes as topical skin protectants
EP1255761B1 (en) 2000-02-07 2005-08-31 Biocompatibles UK Limited Silicon containing compounds from michael - type addition reactions useful as monomers and macromers
US6451438B1 (en) 2000-11-30 2002-09-17 Mearthane Products Corporation Copolymerization of reactive silicone and urethane precursors for use in conductive, soft urethane rollers
US7976936B2 (en) * 2002-10-11 2011-07-12 University Of Connecticut Endoprostheses
US7084188B2 (en) * 2003-12-05 2006-08-01 Bausch & Lomb Incorporated Surface modification of contact lenses
US7176268B2 (en) * 2003-12-05 2007-02-13 Bausch & Lomb Incorporated Prepolymers for improved surface modification of contact lenses
EP1773893B1 (en) * 2004-08-03 2010-06-02 Agency for Science, Technology and Research Polymer having interconnected pores for drug delivery and method
WO2008060249A1 (en) * 2006-11-17 2008-05-22 Agency For Science, Technology And Research Porous polymeric material with cross-linkable wetting agent
ATE481435T1 (en) * 2007-01-12 2010-10-15 Dow Corning COMPOSITION CONTAINING SILICONE
US8222341B2 (en) 2009-03-17 2012-07-17 Mearthane Products Corporation Semi-conductive silicone polymers
JP5697654B2 (en) 2009-03-19 2015-04-08 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ Formation of copolymers from bicontinuous microemulsions containing monomers of different hydrophilicity
US9464159B2 (en) 2009-11-02 2016-10-11 Ocutec Limited Polymers for contact lenses
GB0919459D0 (en) 2009-11-06 2009-12-23 Ocutec Ltd Polymer for contact lenses
EP2496620B1 (en) * 2009-11-02 2014-06-25 Ocutec Limited Polymers for contact lenses
US20110136985A1 (en) * 2009-12-09 2011-06-09 Moon Douglas E Molded article having a mold imparted release layer coating
JP2014032273A (en) * 2012-08-02 2014-02-20 Talex Optical Co Ltd Photochromic lens
EP2895894B1 (en) 2012-09-14 2023-08-23 Ocutec Limited Polymers for contact lenses
JP2015011305A (en) * 2013-07-02 2015-01-19 スタンレー電気株式会社 Device and method for attaching soft contact lens
CN113773794A (en) * 2021-08-27 2021-12-10 金冠电气股份有限公司 High-barrier PBT-polysiloxane copolymer-based composite material for packaging lightning arrester

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3179622A (en) * 1962-03-26 1965-04-20 Dow Corning Polysiloxane isocyanates
US3562352A (en) * 1968-09-06 1971-02-09 Avco Corp Polysiloxane-polyurethane block copolymers
FR2168221A1 (en) * 1972-01-21 1973-08-31 Pechiney Ugine Kuhlmann Polyurethane copolymers - used for coatings esp on textiles
DE2730744A1 (en) * 1977-07-07 1979-05-03 Bayer Ag ORGANOPOLYSILOXANE COMPOSITIONS MODIFIED WITH POLYURETHANE
US4292423A (en) * 1979-04-19 1981-09-29 Wacker-Chemie Gmbh Process for the preparation of organopolysiloxanes
JPS57156005A (en) * 1981-03-20 1982-09-27 Nitto Electric Ind Co Ltd Selective permeable membrane
US4692476A (en) * 1983-12-09 1987-09-08 Rogers Corporation Complex block multipolymer surfactants
US4644046A (en) * 1984-06-20 1987-02-17 Teijin Limited Ultrathin film, process for production thereof, and use thereof for concentrating a specific gas from a gas mixture
US4590224A (en) * 1984-08-20 1986-05-20 The Dow Chemical Company Siloxane-containing polyisocyanurate
DE3517612A1 (en) * 1985-05-15 1987-01-02 Titmus Eurocon Kontaktlinsen MODIFIED SILICONE RUBBER AND ITS USE AS A MATERIAL FOR AN OPTICAL LENS AND OPTICAL LENS OF THIS MATERIAL
JPS6383121A (en) * 1986-09-29 1988-04-13 Toshiba Silicone Co Ltd Production of polyurethane/polysiloxane graft copolymer
US4740533A (en) * 1987-07-28 1988-04-26 Ciba-Geigy Corporation Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof
EP0362137A3 (en) * 1988-09-28 1991-09-04 Ciba-Geigy Ag Molded polymers with hydrophilic surfaces, and process for making them

Also Published As

Publication number Publication date
IE63682B1 (en) 1995-05-31
AU629252B2 (en) 1992-10-01
EP0367720B1 (en) 1994-07-20
TW205557B (en) 1993-05-11
HK9297A (en) 1997-01-31
PT92162B (en) 1996-04-30
DK547189D0 (en) 1989-11-02
CA2001969C (en) 2000-05-30
DE68916907T2 (en) 1994-11-24
JP2845998B2 (en) 1999-01-13
ATE108809T1 (en) 1994-08-15
EP0367720A3 (en) 1991-07-03
IE893531L (en) 1990-05-03
PT92162A (en) 1990-05-31
AU4385289A (en) 1990-05-10
EP0367720A2 (en) 1990-05-09
DK547189A (en) 1990-05-04
DE68916907D1 (en) 1994-08-25
ES2057173T3 (en) 1994-10-16
JPH02180920A (en) 1990-07-13
US4962178A (en) 1990-10-09

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