CA2041260A1 - Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents - Google Patents

Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents

Info

Publication number
CA2041260A1
CA2041260A1 CA002041260A CA2041260A CA2041260A1 CA 2041260 A1 CA2041260 A1 CA 2041260A1 CA 002041260 A CA002041260 A CA 002041260A CA 2041260 A CA2041260 A CA 2041260A CA 2041260 A1 CA2041260 A1 CA 2041260A1
Authority
CA
Canada
Prior art keywords
diagnostic
processes
preparation
ultrasonic contrast
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002041260A
Other languages
French (fr)
Other versions
CA2041260C (en
Inventor
Raimund Erbel
Rainer Zotz
Volker Krone
Michael Magerstadt
Axel Walch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DR F KOEHLER CHEMIE GmbH
Original Assignee
Raimund Erbel
Rainer Zotz
Volker Krone
Michael Magerstadt
Axel Walch
Hoechst Aktiengesellschaft
Aventis Research & Technologies Gmbh & Co. Kg
Dr. F. Koehler Chemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raimund Erbel, Rainer Zotz, Volker Krone, Michael Magerstadt, Axel Walch, Hoechst Aktiengesellschaft, Aventis Research & Technologies Gmbh & Co. Kg, Dr. F. Koehler Chemie Gmbh filed Critical Raimund Erbel
Publication of CA2041260A1 publication Critical patent/CA2041260A1/en
Application granted granted Critical
Publication of CA2041260C publication Critical patent/CA2041260C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The invention relates to ultrasonic contrast agents composed of microparticles which contain a gas and polyamino-dicarboxylic acid-co-imide derivatives, to processes for their preparation and to their use as diagnostic and therapeutic agents.
CA002041260A 1990-04-26 1991-04-25 Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents Expired - Lifetime CA2041260C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4013231 1990-04-26
DEP4013231.5 1990-04-26

Publications (2)

Publication Number Publication Date
CA2041260A1 true CA2041260A1 (en) 1991-10-27
CA2041260C CA2041260C (en) 2002-01-01

Family

ID=6405083

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002041260A Expired - Lifetime CA2041260C (en) 1990-04-26 1991-04-25 Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents

Country Status (9)

Country Link
US (1) US5137928A (en)
EP (1) EP0458079B1 (en)
JP (1) JP3381930B2 (en)
AT (1) ATE108666T1 (en)
CA (1) CA2041260C (en)
DE (1) DE59102225D1 (en)
DK (1) DK0458079T3 (en)
ES (1) ES2058978T3 (en)
IE (1) IE65065B1 (en)

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Also Published As

Publication number Publication date
ATE108666T1 (en) 1994-08-15
JPH04225926A (en) 1992-08-14
JP3381930B2 (en) 2003-03-04
IE911385A1 (en) 1991-11-06
DE59102225D1 (en) 1994-08-25
US5137928A (en) 1992-08-11
EP0458079A3 (en) 1992-01-02
ES2058978T3 (en) 1994-11-01
EP0458079A2 (en) 1991-11-27
CA2041260C (en) 2002-01-01
DK0458079T3 (en) 1994-11-21
EP0458079B1 (en) 1994-07-20
IE65065B1 (en) 1995-10-04

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