CA2061520A1 - Delivery system for enhanced onset and increased potency - Google Patents
Delivery system for enhanced onset and increased potencyInfo
- Publication number
- CA2061520A1 CA2061520A1 CA002061520A CA2061520A CA2061520A1 CA 2061520 A1 CA2061520 A1 CA 2061520A1 CA 002061520 A CA002061520 A CA 002061520A CA 2061520 A CA2061520 A CA 2061520A CA 2061520 A1 CA2061520 A1 CA 2061520A1
- Authority
- CA
- Canada
- Prior art keywords
- delivery system
- increased potency
- enhanced onset
- onset
- enhanced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Abstract
The invention discloses a swallow tablet which is capable of disintegrating within less than about fifteen minutes and providing fast delivery of therapeutic drugs. The delivery system is composed of between 0.250 and 1.0 Gm of an alkali metal or alkaline-earth metal salt of an edible organic acid.
A preferred delivery system is trisodium citrate.
A preferred delivery system is trisodium citrate.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67616591A | 1991-03-27 | 1991-03-27 | |
US676,165 | 1991-03-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2061520A1 true CA2061520A1 (en) | 1992-09-28 |
CA2061520C CA2061520C (en) | 2003-04-22 |
Family
ID=24713495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002061520A Expired - Fee Related CA2061520C (en) | 1991-03-27 | 1992-02-19 | Delivery system for enhanced onset and increased potency |
Country Status (6)
Country | Link |
---|---|
US (2) | US5424075A (en) |
EP (1) | EP0505872A1 (en) |
JP (1) | JPH05112445A (en) |
KR (1) | KR100238550B1 (en) |
AU (1) | AU636810B2 (en) |
CA (1) | CA2061520C (en) |
Families Citing this family (52)
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---|---|---|---|---|
US5922351A (en) * | 1991-03-27 | 1999-07-13 | Bayer Corporation | Lubricants for use in tabletting |
CA2061520C (en) * | 1991-03-27 | 2003-04-22 | Lawrence J. Daher | Delivery system for enhanced onset and increased potency |
DE4341310A1 (en) * | 1993-12-03 | 1995-06-08 | Hexal Pharma Gmbh | Tablet or capsule containing stable ranitidine hydrochloride Form 1 |
US5994348A (en) | 1995-06-07 | 1999-11-30 | Sanofi | Pharmaceutical compositions containing irbesartan |
US6348216B1 (en) * | 1996-06-10 | 2002-02-19 | Knoll Pharmaceutical Company | Ibuprofen and narcotic analgesic compositions |
US6361794B1 (en) | 1996-06-12 | 2002-03-26 | Basf Corporation | Method of making ibuprofen and narcotic analgesic composition |
TW482675B (en) * | 1997-01-31 | 2002-04-11 | Green Cross Corp | Compositions for oral administration containing pyridazinone compounds technical field of the invention |
US5728401A (en) * | 1997-04-16 | 1998-03-17 | Ranbaxy Laboratories, Ltd. | Effervescent ranitidine formulations |
NZ333474A (en) | 1998-01-02 | 1999-06-29 | Mcneil Ppc Inc | A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat |
US6197347B1 (en) | 1998-06-29 | 2001-03-06 | Andrx Pharmaceuticals, Inc. | Oral dosage for the controlled release of analgesic |
CA2343148C (en) * | 1998-09-10 | 2005-11-15 | Nycomed Danmark A/S | Quick release pharmaceutical compositions of drug substances |
US8231899B2 (en) * | 1998-09-10 | 2012-07-31 | Nycomed Danmark Aps | Quick release pharmaceutical compositions of drug substances |
AU783656B2 (en) | 1999-09-02 | 2005-11-24 | Nostrum Pharmaceuticals, Inc. | Controlled release oral dosage suitable for oral administration |
US6264984B1 (en) | 1999-12-06 | 2001-07-24 | Bristol-Myers Squibb Company | Effervescent histamine H2 antagonist composition |
PT1235558E (en) * | 1999-12-09 | 2006-09-29 | Boots Co Plc | THERAPEUTIC AGENTS |
JP2004514732A (en) * | 2000-12-06 | 2004-05-20 | ファルマシア・コーポレーション | Rapidly dispersing pharmaceutical composition |
GB0114069D0 (en) * | 2001-06-08 | 2001-08-01 | Smithkline Beecham Plc | Composition |
US7838026B2 (en) | 2001-09-28 | 2010-11-23 | Mcneil-Ppc, Inc. | Burst-release polymer composition and dosage forms comprising the same |
MXPA04002980A (en) | 2001-09-28 | 2005-06-20 | Johnson & Johnson | Dosage forms having an inner core and outer shell with different shapes. |
US20040253312A1 (en) * | 2001-09-28 | 2004-12-16 | Sowden Harry S. | Immediate release dosage form comprising shell having openings therein |
US7122143B2 (en) | 2001-09-28 | 2006-10-17 | Mcneil-Ppc, Inc. | Methods for manufacturing dosage forms |
CH693586A8 (en) * | 2002-10-14 | 2003-12-15 | Roche Consumer Health Ag | Formulation of ibuprofen sodium. |
ITMI20022619A1 (en) * | 2002-12-11 | 2004-06-12 | Ind Italiana Integratori Trei S P A | PHARMACEUTICAL PREPARATIONS FOR VETERINARY USE CONTAINING ACETYLSALICYLIC ACID IN THE FORM OF SOLUBLE BUFFERED POWDER. |
US20040176234A1 (en) * | 2003-03-07 | 2004-09-09 | Baker Hughes Incorporated | Method for improving separation operation of centrifuges and associated improved separation designs |
WO2004093864A1 (en) | 2003-03-21 | 2004-11-04 | Mcneil-Ppc, Inc. | Non-steroidal anti-inflammatory drug dosing regimen |
US20040186180A1 (en) * | 2003-03-21 | 2004-09-23 | Gelotte Cathy K. | Non-steroidal anti-inflammatory drug dosing regimen |
US20080020042A1 (en) * | 2003-10-14 | 2008-01-24 | Peter Gruber | Dosage form of sodium ibuprofen |
US20050095299A1 (en) * | 2003-10-30 | 2005-05-05 | Wynn David W. | Controlled release analgesic suspensions |
US20050095300A1 (en) * | 2003-10-30 | 2005-05-05 | Wynn David W. | Controlled release analgesic suspensions |
US8067029B2 (en) | 2004-01-13 | 2011-11-29 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
US7879354B2 (en) | 2004-01-13 | 2011-02-01 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
EP1750677B1 (en) * | 2004-05-28 | 2017-02-01 | Imaginot Pty Ltd. | Oral therapeutic compound delivery system |
US8216610B2 (en) * | 2004-05-28 | 2012-07-10 | Imaginot Pty Ltd. | Oral paracetamol formulations |
US20050281876A1 (en) | 2004-06-18 | 2005-12-22 | Shun-Por Li | Solid dosage form for acid-labile active ingredient |
US20060198856A1 (en) * | 2005-03-01 | 2006-09-07 | Keith Whitehead | Ibuprofen suspension stabilized with docusate sodium |
US8673352B2 (en) | 2005-04-15 | 2014-03-18 | Mcneil-Ppc, Inc. | Modified release dosage form |
BRPI0610780A2 (en) * | 2005-04-22 | 2016-09-06 | Teva Pharma | disintegrating tablet pharmaceutical formulation, and methods for treating a patient in need of olanzapine treatment, and for producing the tablet pharmaceutical formulation |
EP1954298A4 (en) * | 2005-11-28 | 2012-10-31 | Imaginot Pty Ltd | Oral therapeutic compound delivery system |
GB2443793B (en) * | 2006-04-05 | 2010-12-01 | Reckitt Benckiser Healthcare | Product, method of manufacture and use |
BRPI0713054A2 (en) * | 2006-06-30 | 2012-04-17 | Mcneil Ppc Inc | solid capsules filled with ibuprofen-containing liquid |
CN101534795B (en) | 2006-11-21 | 2013-04-03 | 麦克内尔-Ppc股份有限公司 | Modified release analgesic suspensions |
US9833510B2 (en) * | 2007-06-12 | 2017-12-05 | Johnson & Johnson Consumer Inc. | Modified release solid or semi-solid dosage forms |
AU2007357647A1 (en) * | 2007-08-15 | 2009-02-19 | Mcneil-Ppc, Inc. | Immediate release and sustained release ibuprofen dosing regimen |
ES2357209B1 (en) * | 2009-05-26 | 2011-12-07 | Fundacion Universitaria San Pablo-Ceu | FAMOTIDINE-BASED SOLID PHARMACEUTICAL COMPOSITION AGAINST GASTRIC HYPERSECRETION AND OTHER RELATED DISEASES, WITH HIGHER SYNERGIC EFFECTIVENESS AND FASTER PERFORMANCE. |
KR101429331B1 (en) * | 2009-06-22 | 2014-08-11 | 와이어쓰 엘엘씨 | Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen |
BR112014019526B8 (en) | 2012-02-07 | 2022-08-30 | Chenango Zero Llc | RAPID RELEASE DOSAGE FORM AND ITS PRODUCTION METHOD |
CN104640537A (en) | 2012-09-18 | 2015-05-20 | 麦克内尔-Ppc股份有限公司 | Low melting propionic acid derivative particles for use in oral dosage forms |
BR112015005968A2 (en) | 2012-09-18 | 2017-07-04 | Mcneil Ppc Inc | sustained release oral dosage forms comprising particles of low melting propionic acid |
CA3031474A1 (en) | 2016-07-19 | 2018-01-25 | Johnson & Johnson Consumer Inc. | Tablets having discontinuous coated regions |
US10583089B2 (en) | 2016-07-19 | 2020-03-10 | Johnson & Johnson Consumer Inc. | Tablets having discontinuous coated regions |
AU2019208501A1 (en) | 2018-01-22 | 2020-07-02 | Johnson & Johnson Consumer Inc. | Perforated capsules |
US20210378968A1 (en) | 2020-05-28 | 2021-12-09 | Johnson & Johnson Consumer Inc. | Multi-cavity customizable dosage forms |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB882567A (en) * | 1959-05-30 | 1961-11-15 | Smith & Nephew | Improvements in or relating to the stabilization of dichloralphenazone |
FR1374388A (en) * | 1963-06-26 | 1964-10-09 | Stamicarbon | Process for the preparation of acetic acid by catalytic oxidation of propylene |
US3803304A (en) * | 1965-07-19 | 1974-04-09 | Armour Pharma | Orally administratable pancreatic enzymes and methods of using same |
FR4924M (en) * | 1965-12-01 | 1967-03-20 | ||
GB1291281A (en) * | 1969-03-20 | 1972-10-04 | Pfizer Ltd | Improvements in pharmaceutical compositions |
US3865935A (en) * | 1972-08-10 | 1975-02-11 | Abbott Lab | Tableting of erythromycin base |
JPS5695113A (en) * | 1979-12-28 | 1981-08-01 | Ajinomoto Co Inc | Antibiotic pharmaceutical for oral administration |
CA1239349A (en) * | 1983-10-10 | 1988-07-19 | Eberhard F. Gottwald | Pharmaceutical composition containing cimetidine |
NL8400911A (en) * | 1984-03-22 | 1985-10-16 | Dagra Nv | PROCESS FOR PREPARING A PHARMACEUTICAL FORM OF ADMINISTRATION CONTAINING TETRACYCLINE OR DOXYCYCLINE SALTS. |
GB8600397D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
FR2593065B1 (en) * | 1986-01-22 | 1988-09-09 | Smith Kline French Lab | EFFERVESCENT COUPLES, EFFERVESCENT COMPOSITIONS OF HISTAMINE H2 ANTAGONISTS CONTAINING THEM AND THEIR PREPARATION. |
YU120988A (en) * | 1988-06-23 | 1990-06-30 | Lek Tovarna Farmacevtskih | Process for preparing new dispersion pills of cimetidine |
US5096714A (en) * | 1988-06-28 | 1992-03-17 | Hauser-Kuhrts, Inc. | Prolonged release drug tablet formulations |
JP2525478B2 (en) * | 1989-03-01 | 1996-08-21 | 帝人株式会社 | Active Vitamin D with improved stability (3) Lower solid preparation |
CA2009326C (en) * | 1989-05-09 | 1998-01-27 | Lawrence J. Daher | Aqueous granulation solution and a method of tablet granulation |
GB8920693D0 (en) * | 1989-09-13 | 1989-10-25 | Nicholas Kiwi Pty Ltd | Non-effervescent ibuprofen compositions |
JPH03112928A (en) * | 1989-09-25 | 1991-05-14 | Otsuka Pharmaceut Co Ltd | Pharmaceutical composition improved in absorbability |
US5064656A (en) * | 1989-11-14 | 1991-11-12 | Dr. Gergely & Co. | Uncoated pharmaceutical reaction tablet |
CA2039742A1 (en) * | 1990-04-23 | 1991-10-24 | Andrew B. Dennis | Tablet composition and method for problem pharmaceutical materials |
EP0533770A1 (en) * | 1990-06-22 | 1993-03-31 | Beecham Group p.l.c. | Novel treatment |
CA2061520C (en) * | 1991-03-27 | 2003-04-22 | Lawrence J. Daher | Delivery system for enhanced onset and increased potency |
JPH09255A (en) * | 1995-04-20 | 1997-01-07 | Daiwa Kasei Kk | Variant type thermolysin yt73 and its gene |
-
1992
- 1992-02-19 CA CA002061520A patent/CA2061520C/en not_active Expired - Fee Related
- 1992-03-16 EP EP92104479A patent/EP0505872A1/en not_active Ceased
- 1992-03-23 JP JP4094863A patent/JPH05112445A/en active Pending
- 1992-03-25 AU AU13179/92A patent/AU636810B2/en not_active Ceased
- 1992-03-26 KR KR1019920004886A patent/KR100238550B1/en not_active IP Right Cessation
- 1992-06-29 US US07/908,527 patent/US5424075A/en not_active Expired - Lifetime
-
1995
- 1995-03-06 US US08/398,722 patent/US5656293A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU636810B2 (en) | 1993-05-06 |
KR100238550B1 (en) | 2000-02-01 |
JPH05112445A (en) | 1993-05-07 |
US5656293A (en) | 1997-08-12 |
AU1317992A (en) | 1992-10-15 |
EP0505872A1 (en) | 1992-09-30 |
US5424075A (en) | 1995-06-13 |
CA2061520C (en) | 2003-04-22 |
KR920017641A (en) | 1992-10-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed | ||
MKLA | Lapsed |
Effective date: 20070219 |