CA2063548A1 - Membrane for isolating virus from solution - Google Patents

Membrane for isolating virus from solution

Info

Publication number
CA2063548A1
CA2063548A1 CA2063548A CA2063548A CA2063548A1 CA 2063548 A1 CA2063548 A1 CA 2063548A1 CA 2063548 A CA2063548 A CA 2063548A CA 2063548 A CA2063548 A CA 2063548A CA 2063548 A1 CA2063548 A1 CA 2063548A1
Authority
CA
Canada
Prior art keywords
substrate
membrane
solution
zone
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2063548A
Other languages
French (fr)
Other versions
CA2063548C (en
Inventor
Anthony J. Dileo
Anthony E. Allegrezza, Jr.
Edmund Tracy Burke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EMD Millipore Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2063548A1 publication Critical patent/CA2063548A1/en
Application granted granted Critical
Publication of CA2063548C publication Critical patent/CA2063548C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/022—Filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B01D61/146—Ultrafiltration comprising multiple ultrafiltration steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/149—Multistep processes comprising different kinds of membrane processes selected from ultrafiltration or microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/12—Composite membranes; Ultra-thin membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
    • B65B31/04—Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S264/00—Plastic and nonmetallic article shaping or treating: processes
    • Y10S264/48—Processes of making filters
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S264/00—Plastic and nonmetallic article shaping or treating: processes
    • Y10S264/62—Processes of molding porous films

Abstract

A composite membrane and process utilizing the membrane which is capable of selectively removing particles such as viral panicles from a solution such as a protein solu-tion is provided. The membrane comprises a porous mem-brane substrate, a surface skin having ultrafiltration separa-tion properties and an intermediate porous zone between the substrate and the skin which intermediate zone has an aver-age pore size smaller than that of the substrate. The interme-diate zone is free of voids which break the skin and which di-realy fluid communicate with the substrate. The composite is capable of a log reduction value of at least 3 (99.9 % remo-val) of particles selectively from solution.
CA002063548A 1990-05-10 1991-04-29 Membrane for isolating virus from solution Expired - Lifetime CA2063548C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/521,784 US5017292A (en) 1990-05-10 1990-05-10 Membrane, process and system for isolating virus from solution
US521,784 1990-05-10

Publications (2)

Publication Number Publication Date
CA2063548A1 true CA2063548A1 (en) 1991-11-11
CA2063548C CA2063548C (en) 1996-10-08

Family

ID=24078147

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002063548A Expired - Lifetime CA2063548C (en) 1990-05-10 1991-04-29 Membrane for isolating virus from solution

Country Status (11)

Country Link
US (2) US5017292A (en)
EP (1) EP0482171B1 (en)
JP (1) JPH0771624B2 (en)
KR (1) KR0173995B1 (en)
AT (1) ATE174527T1 (en)
AU (1) AU636764B2 (en)
CA (1) CA2063548C (en)
DE (1) DE69130637T2 (en)
HU (1) HU213925B (en)
IE (1) IE62498B1 (en)
WO (1) WO1991016968A1 (en)

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US5286280A (en) * 1992-12-31 1994-02-15 Hoechst Celanese Corporation Composite gas separation membrane having a gutter layer comprising a crosslinked polar phenyl-containing - organopolysiloxane, and method for making the same -
US5458719A (en) * 1993-03-24 1995-10-17 Pall Corporation Method for bonding a porous medium to a substrate
CA2128296A1 (en) * 1993-12-22 1995-06-23 Peter John Degen Polyvinylidene fluoride membrane
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US5786058A (en) * 1995-04-03 1998-07-28 Minnesota Mining & Mfg Thermally bonded viral barrier composite
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US7108791B2 (en) * 1999-09-14 2006-09-19 Millipore Corporation High-resolution virus removal methodology and filtration capsule useful therefor
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US6355243B1 (en) * 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US6969515B2 (en) * 1999-11-13 2005-11-29 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US7544500B2 (en) * 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6861001B2 (en) 1999-12-02 2005-03-01 The General Hospital Corporation Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon
ES2374913T3 (en) * 2001-08-01 2012-02-23 Asahi Kasei Medical Co., Ltd. MULTI-PAPER MICROPOROUS PULP.
US7615152B2 (en) 2001-08-23 2009-11-10 Pur Water Purification Products, Inc. Water filter device
US7614507B2 (en) 2001-08-23 2009-11-10 Pur Water Purification Products Inc. Water filter materials, water filters and kits containing particles coated with cationic polymer and processes for using the same
US7614508B2 (en) 2001-08-23 2009-11-10 Pur Water Purification Products Inc. Water filter materials, water filters and kits containing silver coated particles and processes for using the same
KR100777951B1 (en) 2001-08-23 2007-11-28 더 프록터 앤드 갬블 캄파니 Water filter materials, corresponding water filters and processes for using the same
US20050279696A1 (en) 2001-08-23 2005-12-22 Bahm Jeannine R Water filter materials and water filters containing a mixture of microporous and mesoporous carbon particles
AU2003301399B2 (en) * 2002-10-18 2006-07-06 Asahi Kasei Medical Co., Ltd. Microporous hydrophilic membrane
AU2003903507A0 (en) 2003-07-08 2003-07-24 U. S. Filter Wastewater Group, Inc. Membrane post-treatment
US7795010B2 (en) * 2004-01-21 2010-09-14 Toray Industries, Inc. Fractionator and method of fractionation
WO2005073252A1 (en) * 2004-01-30 2005-08-11 Suomen Punainen Risti Veripalvelu Process for the manufacture of virus safe immunoglobulin
JP4748655B2 (en) * 2004-06-25 2011-08-17 ミリポア・コーポレイション Ultrafiltration membrane and manufacturing method
US20080004205A1 (en) 2006-06-30 2008-01-03 Millipore Corporation Ultrafiltration membranes and methods of making
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US20070084788A1 (en) * 2005-10-14 2007-04-19 Millipore Corporation Ultrafiltration membranes and methods of making and use of ultrafiltration membranes
US8562876B2 (en) * 2007-11-30 2013-10-22 Baxter International Inc. Multizone polymer membrane and dialyzer
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CA2726908C (en) * 2008-06-04 2017-01-24 Talecris Biotherapeutics, Inc. Composition, method, and kit for preparing plasmin
US8546127B2 (en) * 2008-06-30 2013-10-01 General Electric Company Bacteria/RNA extraction device
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Also Published As

Publication number Publication date
ATE174527T1 (en) 1999-01-15
KR0173995B1 (en) 1999-02-18
HU9200080D0 (en) 1992-04-28
US5096637A (en) 1992-03-17
WO1991016968A1 (en) 1991-11-14
EP0482171B1 (en) 1998-12-16
CA2063548C (en) 1996-10-08
DE69130637T2 (en) 1999-09-09
JPH04505579A (en) 1992-10-01
HU213925B (en) 1997-11-28
DE69130637D1 (en) 1999-01-28
EP0482171A1 (en) 1992-04-29
HUT63785A (en) 1993-10-28
AU7871591A (en) 1991-11-27
IE62498B1 (en) 1995-02-08
KR920703189A (en) 1992-12-17
IE911503A1 (en) 1991-11-20
US5017292A (en) 1991-05-21
AU636764B2 (en) 1993-05-06
JPH0771624B2 (en) 1995-08-02

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