CA2072580A1 - Steerable infusion guide wire - Google Patents
Steerable infusion guide wireInfo
- Publication number
- CA2072580A1 CA2072580A1 CA2072580A CA2072580A CA2072580A1 CA 2072580 A1 CA2072580 A1 CA 2072580A1 CA 2072580 A CA2072580 A CA 2072580A CA 2072580 A CA2072580 A CA 2072580A CA 2072580 A1 CA2072580 A1 CA 2072580A1
- Authority
- CA
- Canada
- Prior art keywords
- guide wire
- infusion
- lumen
- wire according
- infusion guide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09058—Basic structures of guide wires
- A61M2025/09083—Basic structures of guide wires having a coil around a core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/091—Guide wires having a lumen for drug delivery or suction
Abstract
STEERABLE INFUSION GUIDE WIRE
ABSTRACT OF THE DISCLOSURE
A guide wire having state-of-the-art handling characteristics for ease in positioning a variety of catheters and other devices within the cardiovascular or other body system wherein the guide wire is also suitable for infusion of small volumes of fluid. The exceedingly small diameter guide wire has unique infusion properties.
The guide wire body has at least one helical coil having a flexible non porous sheath within the lumen. The helical coil is close wound along the majority of its length. The distal end of the helical coil has spaced windings to permit infusion of the fluid. The flexible nonporous sheath terminates proximal to the space wound portion. The solid core wire, which runs the entire length of the guide wire, is located within the same lumen used for infusion. This provides a greatly increased surface area in relation to the cross sectional area of the infusion lumen ensuring a slow but extremely constant infusion rate over a wide range of infusion pressures.
ABSTRACT OF THE DISCLOSURE
A guide wire having state-of-the-art handling characteristics for ease in positioning a variety of catheters and other devices within the cardiovascular or other body system wherein the guide wire is also suitable for infusion of small volumes of fluid. The exceedingly small diameter guide wire has unique infusion properties.
The guide wire body has at least one helical coil having a flexible non porous sheath within the lumen. The helical coil is close wound along the majority of its length. The distal end of the helical coil has spaced windings to permit infusion of the fluid. The flexible nonporous sheath terminates proximal to the space wound portion. The solid core wire, which runs the entire length of the guide wire, is located within the same lumen used for infusion. This provides a greatly increased surface area in relation to the cross sectional area of the infusion lumen ensuring a slow but extremely constant infusion rate over a wide range of infusion pressures.
Description
SENT BY:LEriE I~Cr.~GGA~T : 7~ 9'~ :57P~ : 613-)~37~71- ~19 953 953~:# ~?7 . l ~",--c - l ~ ~c .1, . u_ , - ,~ r L ~ t ~ F . ~
2 0 7 2 ~ ~ U
I r~he pr~nt ~y~llcatfon 1~ rel~t~d t~ u~ P~ten~
Appli~at~o~ l NumbRr 120,~78, ~ntitled llollow Lum~
C~b~ App~r~tu~3, and ~ dd ~p~emb~r 30, 1~7~ in th~
na~ ol: Fl~i~cl~h~c~c~r~ Jr.; ana u. ~, P~te~ Appl~ca~ n ~3~rLal NuJnb~r 07~384,39~, ~ntitled ~ollow Lu~on C~ p App ~r~tu~, an~ filed ~uly ~4, lS~B9, in ~he nam6~ 0~
Fl~ i~h~ ak<3r , 3r ~, ~oth au~ign~d to th~ a~sign~ of tl~e prq~nt appll~tion.
tl~ T}{~ IN~E~-IQ2~
Th~ pr~sent lnY~nt~n r~ t~ n~^Ally to madic~a.1 d~ e~ nd more tl~ul2~rly, ~ t~ to yuid~l w~re~ u~d for lnru~ion of f ~ d~ ' 2. ~ n o~ t~ Prl~ - Tl~e U~ o-f guld~
wl~D to ~a~tily lln~ properly po~ on dla~na~tic, th~r~p~utlc, nnd ln~u~ion c::~th~t~r~ bo~n known ~or ~a tlD~ ha abo~a cro~ ft~renc~d co~only a~ ned :ent ~ppllcation~ rolJ1 inc~rporat~2d ~y ro~or~nc~, d~l Icriba the ~atc o~ the ~rt in tha do~lgn, ma~uf~ctUre, u~o o~ ~uid-- wiros.
on~ of the purpO~ or ~uch ~ulde ~ire~
po6~ionln~ of infu~ior~ cathet~r~. Thi~ procedur~
r~ulren th~ attandln~ nl~d~ca~ p~rsDnn~l ~o lns~r~ ~h~
gu;~e ~ire into thr ~oolar :y~ m throug~l ~ punatur: :~
SENT BY:LETTE i~lCT.~GG.~ T : 7~ 9'~: 2:57Pi~ 135637ti71- û19 95~1 9~3~:F 3/~7 IJ~ r, l'~Y~ FPO~! rHL l.~ l rlr~l1 Tn 161.-~St,_.7~
207~39 a ! onv~ or~t lo~ n. ~b gu~d~ wlrc~ is norm~lly ad~r~nc~ und{i~r fluoro~cctpy un~il it~ t~l tlp i~
lo~lt~cl at th6~ d~ d lnr~l~ion 3i'C~. The lnfu~ion ~ot~:~ter 1~ then ~dvanced ove:r thl3 gu~ d~ wlre untll the inr~ on ori~io~ loaBt~d ~t th~s ~nfu~lon ~lt O~t anti~ he gui~æ wlre in r~ o~d to ~ak~ th~ ~ntir~
ara ~ ectit~n~l ar-aa 0~ the il~Pualon a~tl~t~r lum~n ava llnblt~ ~or the pa~ qQ 0~ ~luid.
~ eo~us~ Of the di~:Lcul~ Wit21 thiY proa~dur~, ~tt 3mpt5 h~v~ ~eon macle to mak~ an in~u~1on ~ h~t4r ~h1 ~h ~eqllire~ nn ~para~ gu~cl2 wl~e. U.~. Patent ~o.
I r~he pr~nt ~y~llcatfon 1~ rel~t~d t~ u~ P~ten~
Appli~at~o~ l NumbRr 120,~78, ~ntitled llollow Lum~
C~b~ App~r~tu~3, and ~ dd ~p~emb~r 30, 1~7~ in th~
na~ ol: Fl~i~cl~h~c~c~r~ Jr.; ana u. ~, P~te~ Appl~ca~ n ~3~rLal NuJnb~r 07~384,39~, ~ntitled ~ollow Lu~on C~ p App ~r~tu~, an~ filed ~uly ~4, lS~B9, in ~he nam6~ 0~
Fl~ i~h~ ak<3r , 3r ~, ~oth au~ign~d to th~ a~sign~ of tl~e prq~nt appll~tion.
tl~ T}{~ IN~E~-IQ2~
Th~ pr~sent lnY~nt~n r~ t~ n~^Ally to madic~a.1 d~ e~ nd more tl~ul2~rly, ~ t~ to yuid~l w~re~ u~d for lnru~ion of f ~ d~ ' 2. ~ n o~ t~ Prl~ - Tl~e U~ o-f guld~
wl~D to ~a~tily lln~ properly po~ on dla~na~tic, th~r~p~utlc, nnd ln~u~ion c::~th~t~r~ bo~n known ~or ~a tlD~ ha abo~a cro~ ft~renc~d co~only a~ ned :ent ~ppllcation~ rolJ1 inc~rporat~2d ~y ro~or~nc~, d~l Icriba the ~atc o~ the ~rt in tha do~lgn, ma~uf~ctUre, u~o o~ ~uid-- wiros.
on~ of the purpO~ or ~uch ~ulde ~ire~
po6~ionln~ of infu~ior~ cathet~r~. Thi~ procedur~
r~ulren th~ attandln~ nl~d~ca~ p~rsDnn~l ~o lns~r~ ~h~
gu;~e ~ire into thr ~oolar :y~ m throug~l ~ punatur: :~
SENT BY:LETTE i~lCT.~GG.~ T : 7~ 9'~: 2:57Pi~ 135637ti71- û19 95~1 9~3~:F 3/~7 IJ~ r, l'~Y~ FPO~! rHL l.~ l rlr~l1 Tn 161.-~St,_.7~
207~39 a ! onv~ or~t lo~ n. ~b gu~d~ wlrc~ is norm~lly ad~r~nc~ und{i~r fluoro~cctpy un~il it~ t~l tlp i~
lo~lt~cl at th6~ d~ d lnr~l~ion 3i'C~. The lnfu~ion ~ot~:~ter 1~ then ~dvanced ove:r thl3 gu~ d~ wlre untll the inr~ on ori~io~ loaBt~d ~t th~s ~nfu~lon ~lt O~t anti~ he gui~æ wlre in r~ o~d to ~ak~ th~ ~ntir~
ara ~ ectit~n~l ar-aa 0~ the il~Pualon a~tl~t~r lum~n ava llnblt~ ~or the pa~ qQ 0~ ~luid.
~ eo~us~ Of the di~:Lcul~ Wit21 thiY proa~dur~, ~tt 3mpt5 h~v~ ~eon macle to mak~ an in~u~1on ~ h~t4r ~h1 ~h ~eqllire~ nn ~para~ gu~cl2 wl~e. U.~. Patent ~o.
3,7 $7,7~ ia;ue~ t~ ~lin~ d~crlb~ n~ ~pproa~h to nuch ~ Atb~t6~r~ Th~ Klin~ d~sl~n u~ prlng guldn UVBI
wh~h la plAaed ~4 nh~nt~ To improv~ t:h~ handlln~
ab~ra~t~rl~3tioe, a r~Ymov2lble st~rlet i~; ina~r-tudl lnto tho ~ tral lnfu~ion lum~n. ~rh~ yl~t ~nu~t b~ r~3mova~le ~o prq~ld~ the ~lr~d lnfuslon prop~rtl~ w-~vur, ~ a~ it i~ r~movAbl~, it i~ not avAil~ble t~ trsn~tf~r Oxi~ torquo, j 'rh~ preeent invontion Dv~ct~me~ h~ ~r~bll3m~
,o~l~t~d with tha prior art by prov~ ~ling ~ ~tf2erE-bl~
ln~ US~lc?tl 9uido wir~ huving all ~f ~h~ ad~r~ntng~
~ r~ g~ide~ wlre ~ r~in, -tho c~ntr~l lun~an i~ u~ d ~o .~n:~u~l~n of a rluid. P.~a~u~e th~ ~levlc~ a gu~
wl~e ~ lt c~ aleo b~ ed ~ r pl~c~ent~. o~ ot~r ~vlo~l3 SENT BY:LETTE MCT.-~GGART : 7~ 9~: 2:5BPIM: 6135637671- ~19 953 9538:~ -I/?7 IUI~ J~ rJM Tl~ LI~W l-IRM TD 161~56'7~71 F,~3R
3~ 2872~8~
t~-' ~., cath~t~r~, b~lloonF~, ~ensc:r~ tc~ ~ by remclY$ng th~ ~an~rd fluid o~upling ~ 0, Touhy-Bor6t c~l~n~tor) ~r~ ID ~e pro~ l end. ~rh~ boCI~ o~ ~he g~ide wire h~ at t on6~ out~ ~prlng s:~il with ~ ~lld inner ~:or~ wl~
rurjs~:~ng th~ e7ltir~ 2ngth. Th~ structllre i~ q~xcoll~nt ~ th~ trane~ 13n o~ torqu~ frcnn proximnl to di~tal ~lt . A fl~xlhle~ ~heAth Witllin ~ha out~3r ~pxin~s c~
ona ureq~ ~h~t the ~truc:tur~ doe~ n~t lfla)c proxlmal to th~
in~ unlon 3ittl. Pl~aem~nt oE ~he ~l~x~ble ~he~l~h in~da, rnt h~r ~han outu~do ~P the out~r ~oll, mlnlmi~es ~r~1 .~rfor~nce of ~he nhe~t~ Wi~h torqUU 'c~Ynnmi~iOn ~h~ ough th~ c~
~r~ ln body o~ ~h~ upring ~11 la ol~ ~und ~or lmlim c~JIt~ol. Th~ ~prinq coll n~ay be ~;paco wound ~t t~o ~ tal ~nd, how~v~r, ta provld~ ~nruslan port.
In~u~ing ~lUld ~lr~ugh the c~ pe~cit~ 'cha ~prlng coll to ¦ ~un to th~ tal ~lp o~ thc d~ provldin~ th~
da~ ~ir4d ~l~t~l ~teerabilit~.
Th~ c~ntral lum~n can~a~ning ~h~ p8~m~nent core wir~
~ u~d f~r pa~Bag~ of tho inru~ion ~luid. Tho coLo wire 1~ tap~rad ~t th~ di~tal ~nd t~ ~nhanc~ h~ndlinq ~h~ ~a~arlstiG~ o~ ~h~ gulde wir~. ~hi~ ~lso lncr~a~
th~ ~ ~rP~s~6ectlonal ~rQa o~ ts~e ~ntral lu~n a~ailabl~
~o ~h~ ln u~ion li~uid n~cat~nq ~ r~r~e ventuF~ ~f~eat ~n~ I ~nu~ing the f luid t~ ~ wee~ ~rom the ln~u~ion po~t~ nt ~on~tHn~ r~t~ for ~ con~tAn~ insusl~sl pre~ur~.
SENT BY:LETTE MCTAGGA~T : 7-21-9'~ :5~PM: 6135637671- 819 953 953~:~ 5~'~7 JUI~ c,~ 1 FR~JPI lHr Lf~l~l FIR~I T~l )fil.~,=~ 'l R.Og 1~ ~ 2~72~Q
B~uee the ~ro~s-~atlon~l ~xen 1~ ~lghly ln~lu~nced ~y ~h~ ro~ of tnp~x of th~ cor~ wir~l, th~ in~u~ion ~ate ~t L g~v~n p~6~r~ ~ t~r~by controllabl~. Th~ ~y~t~m i~ I p~rt~ularly s~ici~m ~or pr~ R dicpon~ln~ of h$g~1y cono~ntrat~ Plulds a~ r~ta looati~
~ th~r ob~ct~ o~ ~hM p~e~nt i~v~ntlon and ~ny o~
~hol ~tten~ant ~d~n~ f tbe pre~ent ln~enti~n will~b~
ro~dlly ~ppr~ai~t~d n~ th~ u bocom~ bQtt~r understood by r~fQrance to ~he ~oll~wlng d~ta~ crip~l~n wh~
c~ ~ld~red ln c~nn~ctiOn with the na~ompan~ln~ dr~lng~, in whlch llkR r~fer~nc~ nu~erals designat~ liks par~s o~hDut th~ Elgureu th~r~oE an~ whor~ln:
irl~. L i~ nc:~ptuE~Il vi~ o~ an in~usion ~Uid~
w~ra auoor~in~ t~ ~h~ p~c~nt in~n~lon i is n pnrtl~llly 6ectl~n~d view ~ th~
c~d ~n~Dd~m~nt o~ t~ p~ n~ inv~ntlo~;
~ An Qxplod~d vle~ of th~ aomponent~ ~ the in1 uai~ uide wlro ~ FIG. ~;
~ X~. ~ ls a ~ar~ially s~c~ioned v~ew of an ~11 l~rn~tiv~ ~mbndim~nt ~f th~; pr~nt invention;
~ IC. 5 1~ ~n ~xpl~ v~ ew of the ~o~ponent~ o~ tha ln~uslon gu~d~ wlre of FIG. 4;, ~ Ia. 6 i~ a partl~lly l~ectlon~d ~1QW OP ~ ~and ~l~ern~lv~ ~mbodl~n~ ~ th~. pro4ænt lnv~ntlon;
SENT BY:LETTE MCT.~GGART : 7-21-92: 2:59PM: 6135637671- ~19 953 95~:X 6~ '7 Illr~ 'LII;I l~lt I ~W FIRt1 TCI lL.l.i'ifi.-~7671 i ! -5~ 7 2 ij ~} 0 7 1~ 2n ~xpl~d~ vie~ o~ th~ a~pon~nt~ Df t~
~ni U~ion guid~ wire oP FIG. 6;
FI~ is a u~3a~ion~d v1e~ uf thi3 ~1~t~1 t~p thi Ird ~l~Qrn~ e~ ,odim~nt, I J10. ~ i~ a ~atlon~l vie~ of ~he di~tal tip of ~rth al~rn~t1v~ nt;
~a~ par~l~lly ~c~lon~d v~ew ~ rt~
a~ rnAtivQ ~mbo~ nt;
n explod~3d vi~w o~ ~h~ main aompanantE
Of ith~ fiY~h ~l~ernat~ mbodi~nent;
~ Ia. 12 ia a ~QctionQ~ ~riew o~ tlle di~:t~l tlp o~ a ~i~Fth nltern~civ~ nt~ nnd, FI~. 13 1~ ~ a~ctit~ d vi~w of th-l di~t~1 tip ~f 2,
wh~h la plAaed ~4 nh~nt~ To improv~ t:h~ handlln~
ab~ra~t~rl~3tioe, a r~Ymov2lble st~rlet i~; ina~r-tudl lnto tho ~ tral lnfu~ion lum~n. ~rh~ yl~t ~nu~t b~ r~3mova~le ~o prq~ld~ the ~lr~d lnfuslon prop~rtl~ w-~vur, ~ a~ it i~ r~movAbl~, it i~ not avAil~ble t~ trsn~tf~r Oxi~ torquo, j 'rh~ preeent invontion Dv~ct~me~ h~ ~r~bll3m~
,o~l~t~d with tha prior art by prov~ ~ling ~ ~tf2erE-bl~
ln~ US~lc?tl 9uido wir~ huving all ~f ~h~ ad~r~ntng~
~ r~ g~ide~ wlre ~ r~in, -tho c~ntr~l lun~an i~ u~ d ~o .~n:~u~l~n of a rluid. P.~a~u~e th~ ~levlc~ a gu~
wl~e ~ lt c~ aleo b~ ed ~ r pl~c~ent~. o~ ot~r ~vlo~l3 SENT BY:LETTE MCT.-~GGART : 7~ 9~: 2:5BPIM: 6135637671- ~19 953 9538:~ -I/?7 IUI~ J~ rJM Tl~ LI~W l-IRM TD 161~56'7~71 F,~3R
3~ 2872~8~
t~-' ~., cath~t~r~, b~lloonF~, ~ensc:r~ tc~ ~ by remclY$ng th~ ~an~rd fluid o~upling ~ 0, Touhy-Bor6t c~l~n~tor) ~r~ ID ~e pro~ l end. ~rh~ boCI~ o~ ~he g~ide wire h~ at t on6~ out~ ~prlng s:~il with ~ ~lld inner ~:or~ wl~
rurjs~:~ng th~ e7ltir~ 2ngth. Th~ structllre i~ q~xcoll~nt ~ th~ trane~ 13n o~ torqu~ frcnn proximnl to di~tal ~lt . A fl~xlhle~ ~heAth Witllin ~ha out~3r ~pxin~s c~
ona ureq~ ~h~t the ~truc:tur~ doe~ n~t lfla)c proxlmal to th~
in~ unlon 3ittl. Pl~aem~nt oE ~he ~l~x~ble ~he~l~h in~da, rnt h~r ~han outu~do ~P the out~r ~oll, mlnlmi~es ~r~1 .~rfor~nce of ~he nhe~t~ Wi~h torqUU 'c~Ynnmi~iOn ~h~ ough th~ c~
~r~ ln body o~ ~h~ upring ~11 la ol~ ~und ~or lmlim c~JIt~ol. Th~ ~prinq coll n~ay be ~;paco wound ~t t~o ~ tal ~nd, how~v~r, ta provld~ ~nruslan port.
In~u~ing ~lUld ~lr~ugh the c~ pe~cit~ 'cha ~prlng coll to ¦ ~un to th~ tal ~lp o~ thc d~ provldin~ th~
da~ ~ir4d ~l~t~l ~teerabilit~.
Th~ c~ntral lum~n can~a~ning ~h~ p8~m~nent core wir~
~ u~d f~r pa~Bag~ of tho inru~ion ~luid. Tho coLo wire 1~ tap~rad ~t th~ di~tal ~nd t~ ~nhanc~ h~ndlinq ~h~ ~a~arlstiG~ o~ ~h~ gulde wir~. ~hi~ ~lso lncr~a~
th~ ~ ~rP~s~6ectlonal ~rQa o~ ts~e ~ntral lu~n a~ailabl~
~o ~h~ ln u~ion li~uid n~cat~nq ~ r~r~e ventuF~ ~f~eat ~n~ I ~nu~ing the f luid t~ ~ wee~ ~rom the ln~u~ion po~t~ nt ~on~tHn~ r~t~ for ~ con~tAn~ insusl~sl pre~ur~.
SENT BY:LETTE MCTAGGA~T : 7-21-9'~ :5~PM: 6135637671- 819 953 953~:~ 5~'~7 JUI~ c,~ 1 FR~JPI lHr Lf~l~l FIR~I T~l )fil.~,=~ 'l R.Og 1~ ~ 2~72~Q
B~uee the ~ro~s-~atlon~l ~xen 1~ ~lghly ln~lu~nced ~y ~h~ ro~ of tnp~x of th~ cor~ wir~l, th~ in~u~ion ~ate ~t L g~v~n p~6~r~ ~ t~r~by controllabl~. Th~ ~y~t~m i~ I p~rt~ularly s~ici~m ~or pr~ R dicpon~ln~ of h$g~1y cono~ntrat~ Plulds a~ r~ta looati~
~ th~r ob~ct~ o~ ~hM p~e~nt i~v~ntlon and ~ny o~
~hol ~tten~ant ~d~n~ f tbe pre~ent ln~enti~n will~b~
ro~dlly ~ppr~ai~t~d n~ th~ u bocom~ bQtt~r understood by r~fQrance to ~he ~oll~wlng d~ta~ crip~l~n wh~
c~ ~ld~red ln c~nn~ctiOn with the na~ompan~ln~ dr~lng~, in whlch llkR r~fer~nc~ nu~erals designat~ liks par~s o~hDut th~ Elgureu th~r~oE an~ whor~ln:
irl~. L i~ nc:~ptuE~Il vi~ o~ an in~usion ~Uid~
w~ra auoor~in~ t~ ~h~ p~c~nt in~n~lon i is n pnrtl~llly 6ectl~n~d view ~ th~
c~d ~n~Dd~m~nt o~ t~ p~ n~ inv~ntlo~;
~ An Qxplod~d vle~ of th~ aomponent~ ~ the in1 uai~ uide wlro ~ FIG. ~;
~ X~. ~ ls a ~ar~ially s~c~ioned v~ew of an ~11 l~rn~tiv~ ~mbndim~nt ~f th~; pr~nt invention;
~ IC. 5 1~ ~n ~xpl~ v~ ew of the ~o~ponent~ o~ tha ln~uslon gu~d~ wlre of FIG. 4;, ~ Ia. 6 i~ a partl~lly l~ectlon~d ~1QW OP ~ ~and ~l~ern~lv~ ~mbodl~n~ ~ th~. pro4ænt lnv~ntlon;
SENT BY:LETTE MCT.~GGART : 7-21-92: 2:59PM: 6135637671- ~19 953 95~:X 6~ '7 Illr~ 'LII;I l~lt I ~W FIRt1 TCI lL.l.i'ifi.-~7671 i ! -5~ 7 2 ij ~} 0 7 1~ 2n ~xpl~d~ vie~ o~ th~ a~pon~nt~ Df t~
~ni U~ion guid~ wire oP FIG. 6;
FI~ is a u~3a~ion~d v1e~ uf thi3 ~1~t~1 t~p thi Ird ~l~Qrn~ e~ ,odim~nt, I J10. ~ i~ a ~atlon~l vie~ of ~he di~tal tip of ~rth al~rn~t1v~ nt;
~a~ par~l~lly ~c~lon~d v~ew ~ rt~
a~ rnAtivQ ~mbo~ nt;
n explod~3d vi~w o~ ~h~ main aompanantE
Of ith~ fiY~h ~l~ernat~ mbodi~nent;
~ Ia. 12 ia a ~QctionQ~ ~riew o~ tlle di~:t~l tlp o~ a ~i~Fth nltern~civ~ nt~ nnd, FI~. 13 1~ ~ a~ctit~ d vi~w of th-l di~t~1 tip ~f 2,
4~enth alt{:~rnati~ em~odin~nt~
E~ CR~ !F
on~ptual ;.ViRW D~E ~.n in~u~ion guid~
0 ~nlploy1n~ th~ p~e~ont inventlon~ Th~ ou~er ~-~r~a~ Or tb~ m~ln body v~ im~u~ n ~uid~ wi~ lV i~ ~
w~u~d coil a~ ~hown. A uyr~nS~ or other pump #y~te~ may b~ s~allngly coupl0d to th~e proxim#l ~nd o ~nru~ion ~Uide wlrQ 10 by ~t~nd~rd Tou~y-~or~;t oonn~:at4r 1~1 A p~ox~Rl t:1p ~ o ~ld~fl, b~ ed, or sc;ldorQd in, ~u~h a ~a~hion a~ to ~llow pres~uri2e~l ~lul~ to ~nt~r th~ inner lum~n. Touhy~ t ~:UllnelCtOX li! ~n b~3 re~oYed to ~ .llow thc- ln~uE~on ~ wlr~ ~o to run~t~on ~f~ an ~in~ry ~Uido w~r~ t~ rn~ t~t~ p~ m~n~ o oth~r SENT BY:IETTE MCT.`~CC.-iRT : 7-21-9'~: 2:~9PM: ti1'!~637671-- ~19 9~3 9538:~ 7f''7 l~lrl-~-l'J'' I ~: W~ F~OM T~E L~LJ ~ r1 I U ll.i3~Jt~ 671 P. l l ' ~
2~72i~a ~vl~ a.g., c~th~ter~). In th~a pr~rr~d mode, and no~' to b~ tnr3d. P~ ting Df ~he in~r~n~1on, thç~ ~Iu1d to ~ in~uned (n~t ~hob~n~ 1~ 10aded in~c, a ~3yrin~e ~n th~
n~al ~hiun An~ 1~ prf~oLur1z~ lth :luanu~ Cf~
2Ipp~i~d tc~ thc. thumb kno~ att~ched tc~ ~ pi~con tn o~Q~fn) -~ ~h~ pro~url~d fluid ltt conv~y~d through tha body ol~ linft~ 7 guids w1re 1~ tc> .in~u~ on ~r~a 18 loc}3t~d ~t t~el di~tnl ~nd. Infu~on ~r~a 18 l~ ign~d ~or relsa~S~
o~ ~tbe p~ urize~ ~luid ~rom polnt 20 to po1rlt 22 a~
~e~ ~rlbod bQlQw~ Sol~d di~ tip ~ form13d in th~
~r r-~r know~ in ~h~ art by wc~lding, brazil~q, ~ld~rin~, ~tc . .
f~. a i~ ~ partially ~;2tiono~ ow of ~he pX~ ~llsrrQI~d em~n~ of ~hx p~ n1: in~ehtion. Tha ~nqorlor o~ ~tll~u~lon guida wlr~ ~0 ~:ontaln6~ 6lolid cor~
wiro 30 ha~rlng a con~can~ n~e~:er ~ u~ t~ltlally it~ ontir~ lotly~ w~ver, ~he ~l~sndlir~g ~hnrn,c~t~ri~;ti~6 o~ I inruslRn gu~d~ wir~ lo 1~ ~p~ov~d by t/lpQ~:rln~ ~olid uoc~ w~ r-l 30 b~ginnlng at point 32 whic:h is abou'c 5 ~m rl~n th~ di~ t~p. ~rh~ t~4plar in~ tod ~ pOill~ ~Z
roalult~s~ ln ~on~t~s~t inter~iat~ di~qm~ter 34. S~ d cor~
Wi~Q 30 iti!l ~urth~ t~per~d beginnlnw ~bout 2 cm Yron~ the ~lot~ tiE~ ~t p~lnt 36 to ~lnal dl~ er 3~3, Solid cor~
wlr~ 30 fl~rv~ t~ ~re~ m~ torquo e~o~ntly.
SENT BY:LETrE MCT.~GG.~RT : 7-21-9?: ':~9P~ i]35~37ti71- 819 953 9:)3~: ~/'7 J~ U~ LH~ Ih'r'l Tl~ IGl_~C.~:,b7'~
7_ , ' i 2~2~
. 1, . .
~ ol:Ld ~or~ wlr~ ~ O .run~; th~ ~JItlr~ 'ch of th~
lU~n OI inher ooll a~. Inn~r coll a~ i8 pr~er~bly a l3l;>r~r~g ~oil of ~inl~ t~l wlr~ havlng ~ uni~ilar or mull~irllnr confis~ura~lon which i~ alo~o wound to n~ar Poitlt ~. Th~ ~ro~tim~l and el~d that portic~rl dia-t~l t~
pol~t 32 o~ innQr cuil a~ ~re ~sp~aYd to perrni~ infusion of ~I~Q prQ~ uxiz~d fluid.
~ Cov~ring lnner coll 2H at tlle dl~al end o~ ;t~n~
To~ y-E~orst c~onnactor 12 ~nclt ~hown~ to n6~r point 3a i~
Cl~lblo ~h~ath a6 which 1~ pr~~ 1y n thln n~n~porouF-~ol~n~r, ~iliaon~ rubter ~r PTFE 81ee~ . Flexlbl~ J3h~ath 2~ j on~ur~l~ tl~at pressur~3 io ~n~ln~ain~d ~rom g~andard Tou~y-~ornt ~onhn~1~or 12 to lnf u~ion Ar~ lB .
~ l~n~ ~ut~r l~yQr oE in~u~ion gulde wlre lo oon~i~'ca o~ ¦ou~er o~ll 7.4, whlc~h i~ o ~ quadri~ r ~:alnlc~a~
~ ~1 coll. It i~ wound, to ~1~ oppo~ pit~h oE lllner uoil 1 2R to i~rove ~h~ tor~u~ tr~n~ ion alh~ rac~t~ris~l~o o~ infu~ion ~Uld~ wire 10. A~i; wi~h inner cc~ 8, out~r c:oll. ~4 i~3 clo~ WOUIl~ b~w~Qn ~t~ndard 'rOu~y-~or~ oonnector ~ nd th~ dl~t~ nd b~glnn~ ng At p~ t 32. Outor coil ~4 i~ similarly Elpaco WOUIl~ diRt~l ~o point 32 to per~nit lnru~310n o~ ~hQ ~l~ld. ~rh62 in~ U~ion flUiq 1~ d~p~n~d ~ia in~U~ ion p~rt-~ 4~a-40n ~o~ IP~d l~y th~ spac~u ln oute2: aoil 24. ~emi-h~ isp~ al weld ~o~ f ix~dly ~tt~h~ oute~r coil ~4, lnll nr c~il 2~, nnd golid clor~ wir~ ~o, ~ENT RY:LETTE MC`r.-iGG.-~RT : 7-21-9': 3:a~PM: til35ti37ti71- ~19 953 953~:" 9/''7 J~ J'3,' l',"E14 F~IM 1~1~ LPI'l FIRM T~ i63767`1 P. 1-~
2 ~ ~ 2 ~ ~ ~
1 ~h~ r~ i~ely ~mall Pr~ ~ro~ c~ior~al ~ea wl~hlr- tile lum~n of ~nnQr ~oil 2R, whlch i~; nDt o-:aupi~d by ~ aolid cor~ ~lrb 30, 1~ u~ed for p~:sagQ of ~hu lnf~ion ~lul~l. Th18 ~r~3 or~e-~c~iorlal ~r~a 1~
c:~lta~ d dill:t~l to point ~ urs e~ ult of the tap~?ring Die ` ncll~d ~oro W~r~æ 30. The ~ncr~a~d volu~ at th~
tAl ~lp ~r~e~ LY~rs~ nturI e~eat o~u~in~ nn tremely constAn~ ruEllon rate ~t z~ g1v~n inPu~1on p~eur~. ~he do~re~ o t~p~ con~rol~: th~t infu~i~n r~ bl9C~U~ o~ th~ l~rg~ impnct lt ha~ upon frQe cro~
IlL~jt.Lt~nal ~rea.
xi~ hea>ch ~6 is locats~ b~tw~en oUter c~ll 24 ~t~ lnncr aoil a~ in tho pr~:eerr~d ~od1~nt~ H4vin~
ho~th 2~ in~ide Of ~ut~ coll ~ preventFI
fl~ !xlble ~heath 26 ~rom inte~rr~r~)~g w1t~1 ~h~ ~or~ue tr~ ~n~mls~ion prap~r~ie~ Or oUtc~r ac111 24.
, 3 iY nn ~xpladQd V~ tho ma~or cOIupotl~nt~
0~1 ~h~ pre~rrod e~bod~ment of .infu~ion guid~ wire lO-Ali alo~n~ hr~ ~ pr*viou~ly d~c:ribQd.
PI~a. 4 i~ ~ ~ar~ially ~3ct~0n~d v~ ~w o~ a $irf~t n~tlve e~bc~ ntl ln~ul-~on gu1d~ ~lre 1l~, Of 'che pr~t~ent inv~nt1on. Thl~ ~tnbo~ el7t i~ th~ s~ the prtfe~rad on~bod1mant ~xc~pt ~hat ~lexibl~ s~h~ h 26 i3 c~~ ~ted ~nd lts func~lon i~ r~plac~d Wi~h f1~Xibl~ ~h~h 1~1 i lo~-~t~d wi~,hin th~ ïu~n of inn~r ~1l 12~. In thi~
lm~!nt~ th~ lnrus~lon ~luid contact~ the surf~ca o~
i I
.~I-NT RY:I [ I`TE M( I`;~GC~ RT : 7-21-92: 3:l)~PM: til3'i(~37:i71- ~19 953 95~!~:Ul~/27
E~ CR~ !F
on~ptual ;.ViRW D~E ~.n in~u~ion guid~
0 ~nlploy1n~ th~ p~e~ont inventlon~ Th~ ou~er ~-~r~a~ Or tb~ m~ln body v~ im~u~ n ~uid~ wi~ lV i~ ~
w~u~d coil a~ ~hown. A uyr~nS~ or other pump #y~te~ may b~ s~allngly coupl0d to th~e proxim#l ~nd o ~nru~ion ~Uide wlrQ 10 by ~t~nd~rd Tou~y-~or~;t oonn~:at4r 1~1 A p~ox~Rl t:1p ~ o ~ld~fl, b~ ed, or sc;ldorQd in, ~u~h a ~a~hion a~ to ~llow pres~uri2e~l ~lul~ to ~nt~r th~ inner lum~n. Touhy~ t ~:UllnelCtOX li! ~n b~3 re~oYed to ~ .llow thc- ln~uE~on ~ wlr~ ~o to run~t~on ~f~ an ~in~ry ~Uido w~r~ t~ rn~ t~t~ p~ m~n~ o oth~r SENT BY:IETTE MCT.`~CC.-iRT : 7-21-9'~: 2:~9PM: ti1'!~637671-- ~19 9~3 9538:~ 7f''7 l~lrl-~-l'J'' I ~: W~ F~OM T~E L~LJ ~ r1 I U ll.i3~Jt~ 671 P. l l ' ~
2~72i~a ~vl~ a.g., c~th~ter~). In th~a pr~rr~d mode, and no~' to b~ tnr3d. P~ ting Df ~he in~r~n~1on, thç~ ~Iu1d to ~ in~uned (n~t ~hob~n~ 1~ 10aded in~c, a ~3yrin~e ~n th~
n~al ~hiun An~ 1~ prf~oLur1z~ lth :luanu~ Cf~
2Ipp~i~d tc~ thc. thumb kno~ att~ched tc~ ~ pi~con tn o~Q~fn) -~ ~h~ pro~url~d fluid ltt conv~y~d through tha body ol~ linft~ 7 guids w1re 1~ tc> .in~u~ on ~r~a 18 loc}3t~d ~t t~el di~tnl ~nd. Infu~on ~r~a 18 l~ ign~d ~or relsa~S~
o~ ~tbe p~ urize~ ~luid ~rom polnt 20 to po1rlt 22 a~
~e~ ~rlbod bQlQw~ Sol~d di~ tip ~ form13d in th~
~r r-~r know~ in ~h~ art by wc~lding, brazil~q, ~ld~rin~, ~tc . .
f~. a i~ ~ partially ~;2tiono~ ow of ~he pX~ ~llsrrQI~d em~n~ of ~hx p~ n1: in~ehtion. Tha ~nqorlor o~ ~tll~u~lon guida wlr~ ~0 ~:ontaln6~ 6lolid cor~
wiro 30 ha~rlng a con~can~ n~e~:er ~ u~ t~ltlally it~ ontir~ lotly~ w~ver, ~he ~l~sndlir~g ~hnrn,c~t~ri~;ti~6 o~ I inruslRn gu~d~ wir~ lo 1~ ~p~ov~d by t/lpQ~:rln~ ~olid uoc~ w~ r-l 30 b~ginnlng at point 32 whic:h is abou'c 5 ~m rl~n th~ di~ t~p. ~rh~ t~4plar in~ tod ~ pOill~ ~Z
roalult~s~ ln ~on~t~s~t inter~iat~ di~qm~ter 34. S~ d cor~
Wi~Q 30 iti!l ~urth~ t~per~d beginnlnw ~bout 2 cm Yron~ the ~lot~ tiE~ ~t p~lnt 36 to ~lnal dl~ er 3~3, Solid cor~
wlr~ 30 fl~rv~ t~ ~re~ m~ torquo e~o~ntly.
SENT BY:LETrE MCT.~GG.~RT : 7-21-9?: ':~9P~ i]35~37ti71- 819 953 9:)3~: ~/'7 J~ U~ LH~ Ih'r'l Tl~ IGl_~C.~:,b7'~
7_ , ' i 2~2~
. 1, . .
~ ol:Ld ~or~ wlr~ ~ O .run~; th~ ~JItlr~ 'ch of th~
lU~n OI inher ooll a~. Inn~r coll a~ i8 pr~er~bly a l3l;>r~r~g ~oil of ~inl~ t~l wlr~ havlng ~ uni~ilar or mull~irllnr confis~ura~lon which i~ alo~o wound to n~ar Poitlt ~. Th~ ~ro~tim~l and el~d that portic~rl dia-t~l t~
pol~t 32 o~ innQr cuil a~ ~re ~sp~aYd to perrni~ infusion of ~I~Q prQ~ uxiz~d fluid.
~ Cov~ring lnner coll 2H at tlle dl~al end o~ ;t~n~
To~ y-E~orst c~onnactor 12 ~nclt ~hown~ to n6~r point 3a i~
Cl~lblo ~h~ath a6 which 1~ pr~~ 1y n thln n~n~porouF-~ol~n~r, ~iliaon~ rubter ~r PTFE 81ee~ . Flexlbl~ J3h~ath 2~ j on~ur~l~ tl~at pressur~3 io ~n~ln~ain~d ~rom g~andard Tou~y-~ornt ~onhn~1~or 12 to lnf u~ion Ar~ lB .
~ l~n~ ~ut~r l~yQr oE in~u~ion gulde wlre lo oon~i~'ca o~ ¦ou~er o~ll 7.4, whlc~h i~ o ~ quadri~ r ~:alnlc~a~
~ ~1 coll. It i~ wound, to ~1~ oppo~ pit~h oE lllner uoil 1 2R to i~rove ~h~ tor~u~ tr~n~ ion alh~ rac~t~ris~l~o o~ infu~ion ~Uld~ wire 10. A~i; wi~h inner cc~ 8, out~r c:oll. ~4 i~3 clo~ WOUIl~ b~w~Qn ~t~ndard 'rOu~y-~or~ oonnector ~ nd th~ dl~t~ nd b~glnn~ ng At p~ t 32. Outor coil ~4 i~ similarly Elpaco WOUIl~ diRt~l ~o point 32 to per~nit lnru~310n o~ ~hQ ~l~ld. ~rh62 in~ U~ion flUiq 1~ d~p~n~d ~ia in~U~ ion p~rt-~ 4~a-40n ~o~ IP~d l~y th~ spac~u ln oute2: aoil 24. ~emi-h~ isp~ al weld ~o~ f ix~dly ~tt~h~ oute~r coil ~4, lnll nr c~il 2~, nnd golid clor~ wir~ ~o, ~ENT RY:LETTE MC`r.-iGG.-~RT : 7-21-9': 3:a~PM: til35ti37ti71- ~19 953 953~:" 9/''7 J~ J'3,' l',"E14 F~IM 1~1~ LPI'l FIRM T~ i63767`1 P. 1-~
2 ~ ~ 2 ~ ~ ~
1 ~h~ r~ i~ely ~mall Pr~ ~ro~ c~ior~al ~ea wl~hlr- tile lum~n of ~nnQr ~oil 2R, whlch i~; nDt o-:aupi~d by ~ aolid cor~ ~lrb 30, 1~ u~ed for p~:sagQ of ~hu lnf~ion ~lul~l. Th18 ~r~3 or~e-~c~iorlal ~r~a 1~
c:~lta~ d dill:t~l to point ~ urs e~ ult of the tap~?ring Die ` ncll~d ~oro W~r~æ 30. The ~ncr~a~d volu~ at th~
tAl ~lp ~r~e~ LY~rs~ nturI e~eat o~u~in~ nn tremely constAn~ ruEllon rate ~t z~ g1v~n inPu~1on p~eur~. ~he do~re~ o t~p~ con~rol~: th~t infu~i~n r~ bl9C~U~ o~ th~ l~rg~ impnct lt ha~ upon frQe cro~
IlL~jt.Lt~nal ~rea.
xi~ hea>ch ~6 is locats~ b~tw~en oUter c~ll 24 ~t~ lnncr aoil a~ in tho pr~:eerr~d ~od1~nt~ H4vin~
ho~th 2~ in~ide Of ~ut~ coll ~ preventFI
fl~ !xlble ~heath 26 ~rom inte~rr~r~)~g w1t~1 ~h~ ~or~ue tr~ ~n~mls~ion prap~r~ie~ Or oUtc~r ac111 24.
, 3 iY nn ~xpladQd V~ tho ma~or cOIupotl~nt~
0~1 ~h~ pre~rrod e~bod~ment of .infu~ion guid~ wire lO-Ali alo~n~ hr~ ~ pr*viou~ly d~c:ribQd.
PI~a. 4 i~ ~ ~ar~ially ~3ct~0n~d v~ ~w o~ a $irf~t n~tlve e~bc~ ntl ln~ul-~on gu1d~ ~lre 1l~, Of 'che pr~t~ent inv~nt1on. Thl~ ~tnbo~ el7t i~ th~ s~ the prtfe~rad on~bod1mant ~xc~pt ~hat ~lexibl~ s~h~ h 26 i3 c~~ ~ted ~nd lts func~lon i~ r~plac~d Wi~h f1~Xibl~ ~h~h 1~1 i lo~-~t~d wi~,hin th~ ïu~n of inn~r ~1l 12~. In thi~
lm~!nt~ th~ lnrus~lon ~luid contact~ the surf~ca o~
i I
.~I-NT RY:I [ I`TE M( I`;~GC~ RT : 7-21-92: 3:l)~PM: til3'i(~37:i71- ~19 953 95~!~:Ul~/27
5-~ 2 ~ s ~ rl r~lE Lrll~ rlr~ ;r~3~6~ r~
f l~ible ~ uth 12~ and ~Dlid core w~r~ 30 only . 'l'hiQ
~oc~a~ coh~lon b~ usl~ t~ ln~ n ~l~ld do~
not ~ ontaot .Inner coil l~. In~u~i~n ~uid~ wire 110, tli~ ore, requlr~ lossl lnu~ n pr~8~ure~ ~or a s~ven ln~ J) volum~. ~Ivw~3v~r, lt ~sp~q~u.rs~ ~liqhtly istl~r~r ntl i~ ~ .~ adv~n~d throu~h ~h~ cnrcl iova~ula~ ~y~t~2m ~; ou~r a~1] . a~ an~ r~v~r~o wound iJ~ c~ ra in direct ~c~nt~Rct. Thi~ m~y b~ d~irabl~ n~ ~nner coil l~a ~nd out~ ,r aoil z4 lDck ~own l~tor for mor~ c~lr~ct ~orqu~
trAI i~ml~lon. oth~r c~omponent~ of in~uR10n gu~d~ wir~
0 ! Rre ~B proviuu~ly d~rib~d.
YIB. ~ h ~xplod~d vi~w o~ thn ~n~sior ~omp~nant~
lnYu~sion ~Ul-l~ wire 110. 1~ ompon~llt~; ~r~
r~f~rbhc~d A~OY~ .
I. ~ la a pz~rti~lly aQctloned vl~w o:e a second ~t~rn~tlv~ embodlln~n~ u~iorl ~uidR hrire 210, of th~
prc~L~nt ln~entlon. In~u~lon yuide wlr~ 210 1~ r ~:o inr~l-ion qutdt~ wire 10 u~c~pt t~l~t ~nnl3r ~all 2B ~o~
FIG. ~) ia ellminAtQd. T~e r~ ltinq 6tru~t~lre i~
3a~lly f~brlcatecl ~ncl c~n ~Q m~d~L w1th s~maller f3lr~tnlJion~ for ~1 g~ n ir~u~ion rato b~-c~uo~ i~ h~ ~ewur ao~oh~nts. It In mor~ dirE~cult ~c: trnnflmlt tor~}u~ u~
inllaion guid~ wir~ 210 b~c~u~ o~ th~ a~ nc~ o~ ~le as:f~n~ r~v~ ~ wc~und ooil . ~rh~ in~u~lon chr~ra~t~rl~tia~
~f ~n~uulorl 5~uidG~ w1 r~ 21~ ar~ ~mll~r to ln~ ion gu.~d~
SENT BY:LETTE MC~.~GG.~Rr : 7~ 9~': 3:01PM: ~135637671~ 819 953 9538:~ ''7 ~IJ~ 99~ c, Fr~o~ r~ L~w ~ I RM TO 1~ 3';~ ,`1 r. l'~
, l -lv- 2 ~ ~ 2 wl~e llV b~oau~e ~h~ inu~i~n rluld ~ontact3 only flJx~ hQath 2~ ~nd ~ core wirn 30.
7 i~ Mn ~Xplod~d view o the maj or c~ompan~nt~
Or ~ u~i~n guide wir~ 7.1~. All re~rena~d Ql~an~ ~re a~ jp~viou~ïy d~oribod.
I FIa. ~ iS n ~oati~n~d ~iew o~ ~nfu~lon guida 31~, whl~h i~ ~ third al~rn~tiv~ *mbodl~nt o~ th~
p~l~en~ ih~n~o~l~ Infuion ~uld~ wir~ 31~ l~ nlmil~r to intu~ion guidQ wir~ 210 ~xc~pt that lt nmpl~y~ a ~lh~l~
~l~ar rat~er than a qua~rifll~r out~r ~oil 24 p~o~iding hhtdl~n~ charac~ tics a~o~inted w~ tb ~ ~nglo ~ r ~utd~ wlr~. ~hi~ embo~ n~ al~o employ~ fl oore wir~ 206 h~Ying n aonf~t~nt diameter over 11;FI ~ntir~ g~h -In~u6ion o~cu~ f~om r~latlv~ly c~n~t~n~ ed lnfu~ion ~s A~ ~r~a ~0~ mi-hemi~ph~rlc~l weld ~o~ l~
n~ lly ~ ~ooth wold or ~rn~inq ~ th~ di~t~l tip of ~h~ m~t~llic aom~one~a.
. Y l~ ~ ~eati~n~ v~w or ~h~ dl~tal ~nd o~
infu~iv~ guld~ wlr~ 410 wh.iah i~ ~ fourth nlt~rnntive ~odim~n~ o~ t~1~ p~ nt inY~n~ion. l~hi~ ~bodl~4nt i~
aot~tructe~ ~ lnfu~lon ~uide w~r 310 with t~e ~dl~i~n nor ~pillary tub~ ~o~ . Thi~ tublng i6 avnil~ble ~r~ Poly-M~ cro T~c~olo~$~ no. n~ ~lexi~le Fu~
~i~iCA c~pill~xy ~blng .
I ~0~ lV i~ a partially ~ection~d vi~w D~ n ~ul~e ~ira 30n, ~rploylng ~ th alt~r~ive embodiment o~ tho i SENT BY:LEITE MCT.-~GG.~RT : 7-21-92: 3:01PM: 6l35637671- 819 953 953~: '12~27 Il Ir 1~ L, ~ 'LII`I 1~ LH~ n TO ll~ 'C.7 ,1. I r~. I k , pr~ah~ Y~ntion. Thl~ ~m~ nt 1~ ~im:l lnr to t~a prs~ rr~d embocq1mo~t sxa~pt ~hnt n~ lnn~ co 1 1 3 4~ i~
nc~pç~ul~t~d wlthin ~exible ~hqLat~ 3~. to produ~e lnn~r a~q~lwb1y '1O~. l'h~ ua~ o~ lnn~Lr au~mbly :~O~ pro~fides th~
~v~ntag~ tnq a ~wcl oc~il 0tru~tur~ o FI~.
~, ror tlx~mple~J 1 but prl~v1dQ~ ry~ ernal in~u~i~SI
n rS:r a g~v~" DutZ31d~ d~am~er, ~ec:a~ tho function~
o~ It~o lay~r~ . th~ f lexl~lQ ~h~th an~l th~ lnn~r coil) ar~ accompllLh~d w1~h ~ s~ngle lay~3r ~i.~. lnn~r a~oLmbly 302). All o~hQr c~ on~n~e ar~ ~ pr~vlou~ly dao~ribod .
FIa. ~ An ~3xplod~d Vi~t~Y of tho ma~or ~o~aponent~
u~d~ wlre ~0 o~ . lO. r~v~n 'though lnnar aoil 306 1D I sliown a~ ~ h~lic~l wo~ d ooil, :lt muy also be d ~tru4~ur1~ o~ ~ppropri~t4 ~ti~fn~ and at~en~th.
Inr~ar col~ 3~6 (or ~ltern~lve ~r~id~d Btru~ture~ 1 ~n~paul~t~d wi~1:ln ~l~xl~ hoat:h 3Q~I by moï~gln~, di~ n~, ur o~hQr ~uituble ~tta~hm~n~ Uns.
rlo, ~a i~ ~ sect~ on~ vlew o~ th~ di~tnl tlp o~
~uid~ wire 400 Ymplo~i~ g ~ sixth ~lternDtivu -mbod~mQnt th~ pre~ent ln~n~i~n. Thi~ ~2mhodlmen~ imilar ln co;~truation ~nd~ op~grat ~ n ~o th~ di.~nt of guld~
wlr~ 300 ~sno Al~r~ FIG. lo) ~-x~pt out~ oil ~q i~
7ln rlln~. Thi~s pr~ducl~A tln~ ~ooth, ovO1lly llp~ced ini~uelon port~ a'c ar~a 204~ Outur ooll 2~ msy, 0~
aoq~e~ ~e wound in ott~r ~on~lgur~tionE; wi~laut limi~lng I
SENT BY:LEI~E MCT.~GGART : 7-21-9.': 3:i~lP~ ti13~37~71- ~19 9~3 953~: 13~'7 J UN~ >--1 'J~ UM , ~IE U~IJ f: I ~tl1 Tn l ~ t ,~.63r~1 r~
ill! 't ~ , 2~72~0 1 2-- . I
the I px~ nt lhv~nt10n . Th~ pr~s~nt embo~lmellt~ ~re pro~rld~ad by way of ~x~mple only.
lli'XB. 1:3 :i1 B cr~ otion~l vi~?W o~ tl ~ di~l ti~
o~ ~ui~e wiro ~u ~ncorpor~ting a ~vG~n1th e~nbodiE~nlk o~
th~l prQl~ent lnvel]~ion. Thi~ emb~ nt i~ s;in~ll~r to thn l~erLc~ure og lnf~ion yuldQ wlre 400 ~;ee ~ o ~IG. 12) exc;tept lnnQr coil 306 ~xt~nd~s pr~xlm~lly ~nd di6~t~lly ç~f flekibl~ ~henth 304. Th~ re~ulting guld~ wlre 500 1 r to tho e~l~odim~nt~ ~f Fl(;:~3. 2 and 4 exc~pt th~
th~ oro~ tiollAl ai~ small~3r f~r a ~iv~n lu~en I Having thu~ du~c~rlbed ~, nul~Db~t~ ~f ombadimen~s~ o~ th~
pr~nt lnven~lon, tho~e nf~ s3k Ln thQ ar~ wlll ~ ~ble h ~ elpply ~ teach~nyE~ f~und h~re~n to ye't oth~r ~d~ ntlt with~n th~ uc:vp~3 of ~he c:lalm~ h~reto att~ch~d I cL~r
f l~ible ~ uth 12~ and ~Dlid core w~r~ 30 only . 'l'hiQ
~oc~a~ coh~lon b~ usl~ t~ ln~ n ~l~ld do~
not ~ ontaot .Inner coil l~. In~u~i~n ~uid~ wire 110, tli~ ore, requlr~ lossl lnu~ n pr~8~ure~ ~or a s~ven ln~ J) volum~. ~Ivw~3v~r, lt ~sp~q~u.rs~ ~liqhtly istl~r~r ntl i~ ~ .~ adv~n~d throu~h ~h~ cnrcl iova~ula~ ~y~t~2m ~; ou~r a~1] . a~ an~ r~v~r~o wound iJ~ c~ ra in direct ~c~nt~Rct. Thi~ m~y b~ d~irabl~ n~ ~nner coil l~a ~nd out~ ,r aoil z4 lDck ~own l~tor for mor~ c~lr~ct ~orqu~
trAI i~ml~lon. oth~r c~omponent~ of in~uR10n gu~d~ wir~
0 ! Rre ~B proviuu~ly d~rib~d.
YIB. ~ h ~xplod~d vi~w o~ thn ~n~sior ~omp~nant~
lnYu~sion ~Ul-l~ wire 110. 1~ ompon~llt~; ~r~
r~f~rbhc~d A~OY~ .
I. ~ la a pz~rti~lly aQctloned vl~w o:e a second ~t~rn~tlv~ embodlln~n~ u~iorl ~uidR hrire 210, of th~
prc~L~nt ln~entlon. In~u~lon yuide wlr~ 210 1~ r ~:o inr~l-ion qutdt~ wire 10 u~c~pt t~l~t ~nnl3r ~all 2B ~o~
FIG. ~) ia ellminAtQd. T~e r~ ltinq 6tru~t~lre i~
3a~lly f~brlcatecl ~ncl c~n ~Q m~d~L w1th s~maller f3lr~tnlJion~ for ~1 g~ n ir~u~ion rato b~-c~uo~ i~ h~ ~ewur ao~oh~nts. It In mor~ dirE~cult ~c: trnnflmlt tor~}u~ u~
inllaion guid~ wir~ 210 b~c~u~ o~ th~ a~ nc~ o~ ~le as:f~n~ r~v~ ~ wc~und ooil . ~rh~ in~u~lon chr~ra~t~rl~tia~
~f ~n~uulorl 5~uidG~ w1 r~ 21~ ar~ ~mll~r to ln~ ion gu.~d~
SENT BY:LETTE MC~.~GG.~Rr : 7~ 9~': 3:01PM: ~135637671~ 819 953 9538:~ ''7 ~IJ~ 99~ c, Fr~o~ r~ L~w ~ I RM TO 1~ 3';~ ,`1 r. l'~
, l -lv- 2 ~ ~ 2 wl~e llV b~oau~e ~h~ inu~i~n rluld ~ontact3 only flJx~ hQath 2~ ~nd ~ core wirn 30.
7 i~ Mn ~Xplod~d view o the maj or c~ompan~nt~
Or ~ u~i~n guide wir~ 7.1~. All re~rena~d Ql~an~ ~re a~ jp~viou~ïy d~oribod.
I FIa. ~ iS n ~oati~n~d ~iew o~ ~nfu~lon guida 31~, whl~h i~ ~ third al~rn~tiv~ *mbodl~nt o~ th~
p~l~en~ ih~n~o~l~ Infuion ~uld~ wir~ 31~ l~ nlmil~r to intu~ion guidQ wir~ 210 ~xc~pt that lt nmpl~y~ a ~lh~l~
~l~ar rat~er than a qua~rifll~r out~r ~oil 24 p~o~iding hhtdl~n~ charac~ tics a~o~inted w~ tb ~ ~nglo ~ r ~utd~ wlr~. ~hi~ embo~ n~ al~o employ~ fl oore wir~ 206 h~Ying n aonf~t~nt diameter over 11;FI ~ntir~ g~h -In~u6ion o~cu~ f~om r~latlv~ly c~n~t~n~ ed lnfu~ion ~s A~ ~r~a ~0~ mi-hemi~ph~rlc~l weld ~o~ l~
n~ lly ~ ~ooth wold or ~rn~inq ~ th~ di~t~l tip of ~h~ m~t~llic aom~one~a.
. Y l~ ~ ~eati~n~ v~w or ~h~ dl~tal ~nd o~
infu~iv~ guld~ wlr~ 410 wh.iah i~ ~ fourth nlt~rnntive ~odim~n~ o~ t~1~ p~ nt inY~n~ion. l~hi~ ~bodl~4nt i~
aot~tructe~ ~ lnfu~lon ~uide w~r 310 with t~e ~dl~i~n nor ~pillary tub~ ~o~ . Thi~ tublng i6 avnil~ble ~r~ Poly-M~ cro T~c~olo~$~ no. n~ ~lexi~le Fu~
~i~iCA c~pill~xy ~blng .
I ~0~ lV i~ a partially ~ection~d vi~w D~ n ~ul~e ~ira 30n, ~rploylng ~ th alt~r~ive embodiment o~ tho i SENT BY:LEITE MCT.-~GG.~RT : 7-21-92: 3:01PM: 6l35637671- 819 953 953~: '12~27 Il Ir 1~ L, ~ 'LII`I 1~ LH~ n TO ll~ 'C.7 ,1. I r~. I k , pr~ah~ Y~ntion. Thl~ ~m~ nt 1~ ~im:l lnr to t~a prs~ rr~d embocq1mo~t sxa~pt ~hnt n~ lnn~ co 1 1 3 4~ i~
nc~pç~ul~t~d wlthin ~exible ~hqLat~ 3~. to produ~e lnn~r a~q~lwb1y '1O~. l'h~ ua~ o~ lnn~Lr au~mbly :~O~ pro~fides th~
~v~ntag~ tnq a ~wcl oc~il 0tru~tur~ o FI~.
~, ror tlx~mple~J 1 but prl~v1dQ~ ry~ ernal in~u~i~SI
n rS:r a g~v~" DutZ31d~ d~am~er, ~ec:a~ tho function~
o~ It~o lay~r~ . th~ f lexl~lQ ~h~th an~l th~ lnn~r coil) ar~ accompllLh~d w1~h ~ s~ngle lay~3r ~i.~. lnn~r a~oLmbly 302). All o~hQr c~ on~n~e ar~ ~ pr~vlou~ly dao~ribod .
FIa. ~ An ~3xplod~d Vi~t~Y of tho ma~or ~o~aponent~
u~d~ wlre ~0 o~ . lO. r~v~n 'though lnnar aoil 306 1D I sliown a~ ~ h~lic~l wo~ d ooil, :lt muy also be d ~tru4~ur1~ o~ ~ppropri~t4 ~ti~fn~ and at~en~th.
Inr~ar col~ 3~6 (or ~ltern~lve ~r~id~d Btru~ture~ 1 ~n~paul~t~d wi~1:ln ~l~xl~ hoat:h 3Q~I by moï~gln~, di~ n~, ur o~hQr ~uituble ~tta~hm~n~ Uns.
rlo, ~a i~ ~ sect~ on~ vlew o~ th~ di~tnl tlp o~
~uid~ wire 400 Ymplo~i~ g ~ sixth ~lternDtivu -mbod~mQnt th~ pre~ent ln~n~i~n. Thi~ ~2mhodlmen~ imilar ln co;~truation ~nd~ op~grat ~ n ~o th~ di.~nt of guld~
wlr~ 300 ~sno Al~r~ FIG. lo) ~-x~pt out~ oil ~q i~
7ln rlln~. Thi~s pr~ducl~A tln~ ~ooth, ovO1lly llp~ced ini~uelon port~ a'c ar~a 204~ Outur ooll 2~ msy, 0~
aoq~e~ ~e wound in ott~r ~on~lgur~tionE; wi~laut limi~lng I
SENT BY:LEI~E MCT.~GGART : 7-21-9.': 3:i~lP~ ti13~37~71- ~19 9~3 953~: 13~'7 J UN~ >--1 'J~ UM , ~IE U~IJ f: I ~tl1 Tn l ~ t ,~.63r~1 r~
ill! 't ~ , 2~72~0 1 2-- . I
the I px~ nt lhv~nt10n . Th~ pr~s~nt embo~lmellt~ ~re pro~rld~ad by way of ~x~mple only.
lli'XB. 1:3 :i1 B cr~ otion~l vi~?W o~ tl ~ di~l ti~
o~ ~ui~e wiro ~u ~ncorpor~ting a ~vG~n1th e~nbodiE~nlk o~
th~l prQl~ent lnvel]~ion. Thi~ emb~ nt i~ s;in~ll~r to thn l~erLc~ure og lnf~ion yuldQ wlre 400 ~;ee ~ o ~IG. 12) exc;tept lnnQr coil 306 ~xt~nd~s pr~xlm~lly ~nd di6~t~lly ç~f flekibl~ ~henth 304. Th~ re~ulting guld~ wlre 500 1 r to tho e~l~odim~nt~ ~f Fl(;:~3. 2 and 4 exc~pt th~
th~ oro~ tiollAl ai~ small~3r f~r a ~iv~n lu~en I Having thu~ du~c~rlbed ~, nul~Db~t~ ~f ombadimen~s~ o~ th~
pr~nt lnven~lon, tho~e nf~ s3k Ln thQ ar~ wlll ~ ~ble h ~ elpply ~ teach~nyE~ f~und h~re~n to ye't oth~r ~d~ ntlt with~n th~ uc:vp~3 of ~he c:lalm~ h~reto att~ch~d I cL~r
Claims (13)
1. An infusion guide wire having a proximal end and a distal end comprising:
a. an outer coil having a proximal end and a distal end and having a first lumen;
b. a flexible sheath having a proximal end and a distal end and having a second lumen located within said first lumen;
c. a core wire having a distal end fixedly d. means sealingly attached to said proximal end of said flexible sheath for inserting a pressurized fluid into said second lumen.
a. an outer coil having a proximal end and a distal end and having a first lumen;
b. a flexible sheath having a proximal end and a distal end and having a second lumen located within said first lumen;
c. a core wire having a distal end fixedly d. means sealingly attached to said proximal end of said flexible sheath for inserting a pressurized fluid into said second lumen.
2. An infusion guide wire according to claim 1 wherein said outer coil is close wound for the majority of its length between said proximal end and said distal end.
3. An infusion guide wire according to claim 2 wherein said distal end of said flexible sheath is not coterminous with said distal end of said outer coil.
4. An infusion guide wire according to claim 3 wherein said outer coil is space wound from said distal end of said flexible sheath to said distal end of said outer coil.
5. An infusion guide wire according to claim 4 further comprising a capillary tube within said second lumen.
6. An infusion guide wire according to claim 5 wherein said outer coil is quadrifilar.
7. An infusion guide wire according to claim 5 wherein said outer sheath is single filar.
8. An infusion guide wire according to claim 4 further comprising an inner coil having a third lumen located within said first lumen wherein said outer coil and said inner coil are oppositely wound.
9. An infusion guide wire according to claim 8 wherein said inner coil is located within said second lumen.
10. An infusion guide wire according to claim 8 wherein said flexible sheath is located within said third lumen.
11. An infusion guide wire according to claim 4 wherein aid flexible sheath further comprised an imbedded metallic reinforcement.
12. An infusion guide wire according to claim 11 wherein said embedded metallic reinforcement further comprises a spring coil.
13. An infusion guide wire according to claim 11 wherein said embedded metallic reinforcement further comprises a braided structure.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/607,454 US5211636A (en) | 1990-10-31 | 1990-10-31 | Steerable infusion guide wire |
| US07/607,454 | 1990-10-31 | ||
| PCT/US1991/008012 WO1992007594A1 (en) | 1990-10-31 | 1991-10-28 | Steerable infusion guide wire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2072580A1 true CA2072580A1 (en) | 1992-05-14 |
Family
ID=24432351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2072580A Abandoned CA2072580A1 (en) | 1990-10-31 | 1991-10-28 | Steerable infusion guide wire |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US5211636A (en) |
| EP (1) | EP0509084B1 (en) |
| CA (1) | CA2072580A1 (en) |
| DE (1) | DE69128710T2 (en) |
| WO (1) | WO1992007594A1 (en) |
Families Citing this family (171)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5211636A (en) * | 1990-10-31 | 1993-05-18 | Lake Region Manufacturing Co., Inc. | Steerable infusion guide wire |
| US5353808A (en) * | 1992-03-04 | 1994-10-11 | Cordis Corporation | Guidewire having distally located marker segment |
| US5716410A (en) * | 1993-04-30 | 1998-02-10 | Scimed Life Systems, Inc. | Temporary stent and method of use |
| US7883474B1 (en) * | 1993-05-11 | 2011-02-08 | Target Therapeutics, Inc. | Composite braided guidewire |
| US5462523A (en) * | 1993-05-18 | 1995-10-31 | Target Therapeutics, Inc. | Drug delivery system |
| US5606981A (en) * | 1994-03-11 | 1997-03-04 | C. R. Bard, Inc. | Catheter guidewire with radiopaque markers |
| US5497783A (en) * | 1994-05-18 | 1996-03-12 | Scimed Life Systems, Inc. | Guidewire having radioscopic tip |
| CH689170A5 (en) * | 1994-07-11 | 1998-11-13 | Weissenfluh Hawe Neos | Flexible post or not deformable radially and longitudinally avvolgimatrici device for dental use. |
| US5522874A (en) * | 1994-07-28 | 1996-06-04 | Gates; James T. | Medical lead having segmented electrode |
| US5522875A (en) * | 1994-07-28 | 1996-06-04 | Medtronic, Inc. | Medical electrical lead system having a torque transfer stylet |
| US5573522A (en) * | 1994-10-11 | 1996-11-12 | Ep Technologies, Inc. | Spring assembly for catheter |
| US5554114A (en) * | 1994-10-20 | 1996-09-10 | Micro Therapeutics, Inc. | Infusion device with preformed shape |
| US5569197A (en) * | 1994-12-21 | 1996-10-29 | Schneider (Usa) Inc | Drug delivery guidewire |
| EP0738495B1 (en) | 1995-04-18 | 2002-06-26 | Schneider (Europe) GmbH | Pressure measuring guide wire |
| EP0739641A1 (en) * | 1995-04-26 | 1996-10-30 | Cordis Corporation | Formable tip guidewire |
| US5551444A (en) * | 1995-05-31 | 1996-09-03 | Radius Medical Technologies, Inc. | Flexible guidewire with radiopaque outer coil and non-radiopaque inner coil |
| US5925016A (en) * | 1995-09-27 | 1999-07-20 | Xrt Corp. | Systems and methods for drug delivery including treating thrombosis by driving a drug or lytic agent through the thrombus by pressure |
| US6027461A (en) * | 1995-10-11 | 2000-02-22 | Micro Therapeutics, Inc. | Infusion guidewire having fixed core wire and flexible radiopaque marker |
| US5997487A (en) * | 1995-10-11 | 1999-12-07 | Micro Therapeutics, Inc. | Infusion wire having fixed core wire |
| US6235007B1 (en) * | 1995-11-27 | 2001-05-22 | Therox, Inc. | Atraumatic fluid delivery devices |
| US5797876A (en) * | 1995-11-27 | 1998-08-25 | Therox, Inc. | High pressure perfusion device |
| US5860938A (en) * | 1996-03-07 | 1999-01-19 | Scimed Life Systems, Inc. | Medical pressure sensing guide wire |
| US5964714A (en) * | 1996-03-07 | 1999-10-12 | Scimed Life Systems, Inc. | Pressure sensing guide wire |
| ATE164772T1 (en) * | 1996-05-03 | 1998-04-15 | Schneider Europ Ag | METHOD FOR PRODUCING A GUIDE WIRE AND GUIDE WIRE |
| US6068623A (en) * | 1997-03-06 | 2000-05-30 | Percusurge, Inc. | Hollow medical wires and methods of constructing same |
| ATE262945T1 (en) * | 1996-05-20 | 2004-04-15 | Medtronic Ave Inc | BALLOON CATHETER WITH EXPANDING CORE WIRE |
| US6022336A (en) | 1996-05-20 | 2000-02-08 | Percusurge, Inc. | Catheter system for emboli containment |
| US5782797A (en) * | 1996-06-06 | 1998-07-21 | Scimed Life Systems, Inc. | Therapeutic infusion device |
| US5993424A (en) * | 1996-08-05 | 1999-11-30 | Cordis Corporation | Guidewire having a distal tip that can change its shape within a vessel |
| US6190332B1 (en) | 1998-02-19 | 2001-02-20 | Percusurge, Inc. | Core wire with shapeable tip |
| US6355016B1 (en) | 1997-03-06 | 2002-03-12 | Medtronic Percusurge, Inc. | Catheter core wire |
| US5827278A (en) * | 1997-05-20 | 1998-10-27 | Cordis Webster, Inc. | Deflectable tip electrode catheter with nylon stiffener and compression coil |
| EP0879617B1 (en) * | 1997-05-21 | 2003-04-16 | Schneider (Europe) GmbH | Pressure monitoring guide wire and method for manufacturing such a guide wire |
| EP0879616A1 (en) * | 1997-05-21 | 1998-11-25 | Schneider (Europe) GmbH | Guide wire |
| US6402719B1 (en) | 1997-09-05 | 2002-06-11 | Cordis Webster, Inc. | Steerable DMR catheter with infusion tube |
| US6132388A (en) | 1997-10-16 | 2000-10-17 | Scimed Life Systems, Inc. | Guide wire tip |
| US6120476A (en) * | 1997-12-01 | 2000-09-19 | Cordis Webster, Inc. | Irrigated tip catheter |
| CN1285900A (en) | 1997-12-31 | 2001-02-28 | 杰克·W·罗马诺 | Method and apparatus for transferring drilling energy to cutting member |
| US20080140101A1 (en) * | 2006-12-07 | 2008-06-12 | Revascular Therapeutic, Inc. | Apparatus for crossing occlusions or stenoses |
| US9254143B2 (en) * | 1998-02-25 | 2016-02-09 | Revascular Therapeutics, Inc. | Guidewire for crossing occlusions or stenoses having a shapeable distal end |
| US20070225615A1 (en) * | 2006-03-22 | 2007-09-27 | Revascular Therapeutics Inc. | Guidewire controller system |
| US6746422B1 (en) | 2000-08-23 | 2004-06-08 | Norborn Medical, Inc. | Steerable support system with external ribs/slots that taper |
| US6059767A (en) * | 1998-02-25 | 2000-05-09 | Norborn Medical, Inc. | Steerable unitary infusion catheter/guide wire incorporating detachable infusion port assembly |
| US20060074442A1 (en) * | 2000-04-06 | 2006-04-06 | Revascular Therapeutics, Inc. | Guidewire for crossing occlusions or stenoses |
| US20050119615A1 (en) * | 2000-04-06 | 2005-06-02 | Norborn Medical, Inc. | Guidewire for crossing occlusions or stenoses |
| US6824550B1 (en) * | 2000-04-06 | 2004-11-30 | Norbon Medical, Inc. | Guidewire for crossing occlusions or stenosis |
| US6340368B1 (en) | 1998-10-23 | 2002-01-22 | Medtronic Inc. | Implantable device with radiopaque ends |
| US6171275B1 (en) | 1998-12-03 | 2001-01-09 | Cordis Webster, Inc. | Irrigated split tip electrode catheter |
| US6361557B1 (en) | 1999-02-05 | 2002-03-26 | Medtronic Ave, Inc. | Staplebutton radiopaque marker |
| DE69927474T2 (en) | 1999-03-29 | 2006-07-06 | William Cook Europe A/S | A guidewire |
| EP1040842B1 (en) | 1999-03-29 | 2004-05-12 | William Cook Europe ApS | A guidewire |
| EP2289448B1 (en) * | 1999-05-11 | 2013-03-13 | Atrionix, Inc. | Tissue ablation system including a balloon anchor wire |
| US7510550B2 (en) | 1999-07-19 | 2009-03-31 | I-Flow Corporation | Catheter for uniform delivery of medication |
| US7547302B2 (en) * | 1999-07-19 | 2009-06-16 | I-Flow Corporation | Anti-microbial catheter |
| US6350253B1 (en) * | 1999-07-19 | 2002-02-26 | I-Flow Corporation | Catheter for uniform delivery of medication |
| US7004923B2 (en) * | 1999-07-19 | 2006-02-28 | I-Flow Corporation | Catheter for uniform delivery of medication |
| US7452353B2 (en) * | 1999-07-19 | 2008-11-18 | I-Flow Corporation | Catheter for uniform delivery of medication |
| AU781910B2 (en) * | 2000-01-28 | 2005-06-23 | Cook Medical Technologies Llc | Endovascular medical device with plurality of wires |
| ATE273038T1 (en) * | 2000-01-28 | 2004-08-15 | Cook William Europ | CATHETER MADE FROM A SERIES OF MULTIFILAMENT WIRES |
| US20040082879A1 (en) * | 2000-01-28 | 2004-04-29 | Klint Henrik S. | Endovascular medical device with plurality of wires |
| US7805188B2 (en) * | 2000-03-24 | 2010-09-28 | Micor, Inc. | Anesthesia conduction catheter for delivery of electrical stimulus |
| US6676643B2 (en) * | 2000-03-24 | 2004-01-13 | Nicor, Inc. | Anesthesia conduction catheter |
| IE20010244A1 (en) * | 2000-04-28 | 2002-04-03 | Medtronic Inc | Occlusion resistant medical catheter with flexible core |
| US7381198B2 (en) | 2000-08-23 | 2008-06-03 | Revascular Therapeutics, Inc. | Steerable distal support system |
| US8721625B2 (en) * | 2001-01-26 | 2014-05-13 | Cook Medical Technologies Llc | Endovascular medical device with plurality of wires |
| US6881194B2 (en) * | 2001-03-21 | 2005-04-19 | Asahi Intec Co., Ltd. | Wire-stranded medical hollow tube, and a medical guide wire |
| US6575920B2 (en) | 2001-05-30 | 2003-06-10 | Scimed Life Systems, Inc. | Distal tip portion for a guide wire |
| EP1283025A1 (en) * | 2001-08-10 | 2003-02-12 | Stöckert Instrumente GmbH | Ballon occlusion device |
| US20030093060A1 (en) * | 2001-11-09 | 2003-05-15 | Vadnais Technologies Corporation | Catheter assembly |
| US8142412B2 (en) | 2002-01-03 | 2012-03-27 | Oxira Medical Inc. | Method and apparatus for delivering oxygen and/or other gases to tissue |
| US6855136B2 (en) * | 2002-04-03 | 2005-02-15 | Gore Enterprise Holdings, Inc. | Infusion catheter having an atraumatic tip |
| US20040147903A1 (en) * | 2002-04-05 | 2004-07-29 | Lucas Latini | Microcatheter having tip relief region |
| US20040064069A1 (en) * | 2002-09-30 | 2004-04-01 | Reynolds Brian R. | Medical device with support member |
| US7758592B2 (en) * | 2002-12-02 | 2010-07-20 | Wilson-Cook Medical Inc. | Loop tip wire guide |
| JP4098613B2 (en) * | 2002-12-11 | 2008-06-11 | 朝日インテック株式会社 | Hollow stranded wire coil body, medical instrument using the same, and manufacturing method thereof |
| US7077811B2 (en) * | 2002-12-23 | 2006-07-18 | Scimed Life Systems, Inc. | Guidewire tip construction |
| US7582740B2 (en) * | 2003-04-17 | 2009-09-01 | The Trustees Of Columbia University In The City Of New York | Methods and kits for detecting SARS-associated coronavirus |
| GB0310715D0 (en) | 2003-05-09 | 2003-06-11 | Angiomed Ag | Strain management in stent delivery system |
| US20040260271A1 (en) * | 2003-06-18 | 2004-12-23 | Huyser Richard F. | Extended fenestration catheter with internal coil and method of making the same |
| US7747314B2 (en) * | 2003-12-30 | 2010-06-29 | Boston Scientific Scimed, Inc. | Distal assembly for a medical device |
| US20050177185A1 (en) * | 2004-02-05 | 2005-08-11 | Scimed Life Systems, Inc. | Counterwound coil for embolic protection sheath |
| US20060095050A1 (en) * | 2004-09-14 | 2006-05-04 | William A. Cook Australia Pty. Ltd. | Large diameter sheath |
| JP4940394B2 (en) * | 2004-09-30 | 2012-05-30 | クック メディカル テクノロジーズ エルエルシー | Steerable wire guide with looped tip |
| US8070693B2 (en) * | 2004-09-30 | 2011-12-06 | Cook Medical Technologies Llc | Articulating steerable wire guide |
| US8784336B2 (en) | 2005-08-24 | 2014-07-22 | C. R. Bard, Inc. | Stylet apparatuses and methods of manufacture |
| US8608703B2 (en) * | 2007-06-12 | 2013-12-17 | Medrad, Inc. | Infusion flow guidewire system |
| US20070083132A1 (en) * | 2005-10-11 | 2007-04-12 | Sharrow James S | Medical device coil |
| US8715205B2 (en) * | 2006-08-25 | 2014-05-06 | Cook Medical Tecnologies Llc | Loop tip wire guide |
| US20080064988A1 (en) * | 2006-09-07 | 2008-03-13 | Wilson-Cook Medical Inc. | Loop Tip Wire Guide |
| US7794407B2 (en) | 2006-10-23 | 2010-09-14 | Bard Access Systems, Inc. | Method of locating the tip of a central venous catheter |
| US8388546B2 (en) | 2006-10-23 | 2013-03-05 | Bard Access Systems, Inc. | Method of locating the tip of a central venous catheter |
| US20080269774A1 (en) | 2006-10-26 | 2008-10-30 | Chestnut Medical Technologies, Inc. | Intracorporeal Grasping Device |
| US8105382B2 (en) | 2006-12-07 | 2012-01-31 | Interventional Spine, Inc. | Intervertebral implant |
| JP5148936B2 (en) * | 2006-12-28 | 2013-02-20 | テルモ株式会社 | Guide wire |
| US8900307B2 (en) | 2007-06-26 | 2014-12-02 | DePuy Synthes Products, LLC | Highly lordosed fusion cage |
| US10751509B2 (en) | 2007-11-26 | 2020-08-25 | C. R. Bard, Inc. | Iconic representations for guidance of an indwelling medical device |
| US9521961B2 (en) | 2007-11-26 | 2016-12-20 | C. R. Bard, Inc. | Systems and methods for guiding a medical instrument |
| US9649048B2 (en) | 2007-11-26 | 2017-05-16 | C. R. Bard, Inc. | Systems and methods for breaching a sterile field for intravascular placement of a catheter |
| US8388541B2 (en) | 2007-11-26 | 2013-03-05 | C. R. Bard, Inc. | Integrated system for intravascular placement of a catheter |
| US10524691B2 (en) | 2007-11-26 | 2020-01-07 | C. R. Bard, Inc. | Needle assembly including an aligned magnetic element |
| US10449330B2 (en) | 2007-11-26 | 2019-10-22 | C. R. Bard, Inc. | Magnetic element-equipped needle assemblies |
| US8781555B2 (en) | 2007-11-26 | 2014-07-15 | C. R. Bard, Inc. | System for placement of a catheter including a signal-generating stylet |
| US8849382B2 (en) | 2007-11-26 | 2014-09-30 | C. R. Bard, Inc. | Apparatus and display methods relating to intravascular placement of a catheter |
| US8231927B2 (en) * | 2007-12-21 | 2012-07-31 | Innovatech, Llc | Marked precoated medical device and method of manufacturing same |
| US8048471B2 (en) * | 2007-12-21 | 2011-11-01 | Innovatech, Llc | Marked precoated medical device and method of manufacturing same |
| US7811623B2 (en) * | 2007-12-21 | 2010-10-12 | Innovatech, Llc | Marked precoated medical device and method of manufacturing same |
| US8231926B2 (en) | 2007-12-21 | 2012-07-31 | Innovatech, Llc | Marked precoated medical device and method of manufacturing same |
| US7714217B2 (en) | 2007-12-21 | 2010-05-11 | Innovatech, Llc | Marked precoated strings and method of manufacturing same |
| EP2471493A1 (en) | 2008-01-17 | 2012-07-04 | Synthes GmbH | An expandable intervertebral implant and associated method of manufacturing the same |
| US8478382B2 (en) | 2008-02-11 | 2013-07-02 | C. R. Bard, Inc. | Systems and methods for positioning a catheter |
| BRPI0910325A8 (en) | 2008-04-05 | 2019-01-29 | Synthes Gmbh | expandable intervertebral implant |
| US9901714B2 (en) | 2008-08-22 | 2018-02-27 | C. R. Bard, Inc. | Catheter assembly including ECG sensor and magnetic assemblies |
| US8437833B2 (en) | 2008-10-07 | 2013-05-07 | Bard Access Systems, Inc. | Percutaneous magnetic gastrostomy |
| US8657821B2 (en) | 2008-11-14 | 2014-02-25 | Revascular Therapeutics Inc. | Method and system for reversibly controlled drilling of luminal occlusions |
| US8162891B2 (en) * | 2008-11-26 | 2012-04-24 | Revascular Therapeutics, Inc. | Delivery and exchange catheter for storing guidewire |
| US20100191150A1 (en) | 2009-01-27 | 2010-07-29 | Palme Jr Robert A | Guidewire |
| US9526620B2 (en) | 2009-03-30 | 2016-12-27 | DePuy Synthes Products, Inc. | Zero profile spinal fusion cage |
| US9532724B2 (en) | 2009-06-12 | 2017-01-03 | Bard Access Systems, Inc. | Apparatus and method for catheter navigation using endovascular energy mapping |
| EP3542713A1 (en) | 2009-06-12 | 2019-09-25 | Bard Access Systems, Inc. | Adapter for a catheter tip positioning device |
| WO2011019760A2 (en) | 2009-08-10 | 2011-02-17 | Romedex International Srl | Devices and methods for endovascular electrography |
| EP2517622A3 (en) | 2009-09-29 | 2013-04-24 | C. R. Bard, Inc. | Stylets for use with apparatus for intravascular placement of a catheter |
| CH701913A1 (en) | 2009-09-30 | 2011-03-31 | Schwager Medica | Guidewire. |
| US11103213B2 (en) | 2009-10-08 | 2021-08-31 | C. R. Bard, Inc. | Spacers for use with an ultrasound probe |
| US9393129B2 (en) | 2009-12-10 | 2016-07-19 | DePuy Synthes Products, Inc. | Bellows-like expandable interbody fusion cage |
| CN102821679B (en) | 2010-02-02 | 2016-04-27 | C·R·巴德股份有限公司 | For the apparatus and method that catheter navigation and end are located |
| WO2011140186A1 (en) | 2010-05-05 | 2011-11-10 | Cook Medical Technologies Llc | Treatment fluid delivery method, and turbulator for promoting uptake of a treatment agent |
| JP5980201B2 (en) | 2010-05-28 | 2016-08-31 | シー・アール・バード・インコーポレーテッドＣ Ｒ Ｂａｒｄ Ｉｎｃｏｒｐｏｒａｔｅｄ | Insertion guidance system for needles and medical components |
| WO2011150376A1 (en) | 2010-05-28 | 2011-12-01 | C.R. Bard, Inc. | Apparatus for use with needle insertion guidance system |
| US20110319905A1 (en) | 2010-06-23 | 2011-12-29 | Palme Robert A | Multiple function vascular device |
| US9282979B2 (en) | 2010-06-24 | 2016-03-15 | DePuy Synthes Products, Inc. | Instruments and methods for non-parallel disc space preparation |
| US8979860B2 (en) | 2010-06-24 | 2015-03-17 | DePuy Synthes Products. LLC | Enhanced cage insertion device |
| EP2588034B1 (en) | 2010-06-29 | 2018-01-03 | Synthes GmbH | Distractible intervertebral implant |
| JP2013535301A (en) | 2010-08-09 | 2013-09-12 | シー・アール・バード・インコーポレーテッド | Ultrasonic probe head support / cover structure |
| US9238119B2 (en) | 2010-08-12 | 2016-01-19 | Boston Scientific Limited | Infusion flow system and fluid coupling |
| BR112013002431B1 (en) | 2010-08-20 | 2021-06-29 | C.R. Bard, Inc | SYSTEM FOR RECONFIRMING THE POSITION OF A CATHETER INSIDE A PATIENT |
| US9014816B2 (en) | 2010-10-07 | 2015-04-21 | W. C. Heraeus Gmbh | Medical lead with filler layer |
| US9402732B2 (en) | 2010-10-11 | 2016-08-02 | DePuy Synthes Products, Inc. | Expandable interspinous process spacer implant |
| EP2632360A4 (en) | 2010-10-29 | 2014-05-21 | Bard Inc C R | Bioimpedance-assisted placement of a medical device |
| US8900652B1 (en) | 2011-03-14 | 2014-12-02 | Innovatech, Llc | Marked fluoropolymer surfaces and method of manufacturing same |
| EP3485851B1 (en) | 2011-03-22 | 2021-08-25 | DePuy Synthes Products, LLC | Universal trial for lateral cages |
| KR20140051284A (en) | 2011-07-06 | 2014-04-30 | 씨. 알. 바드, 인크. | Needle length determination and calibration for insertion guidance system |
| USD724745S1 (en) | 2011-08-09 | 2015-03-17 | C. R. Bard, Inc. | Cap for an ultrasound probe |
| USD699359S1 (en) | 2011-08-09 | 2014-02-11 | C. R. Bard, Inc. | Ultrasound probe head |
| WO2013070775A1 (en) | 2011-11-07 | 2013-05-16 | C.R. Bard, Inc | Ruggedized ultrasound hydrogel insert |
| WO2013188833A2 (en) | 2012-06-15 | 2013-12-19 | C.R. Bard, Inc. | Apparatus and methods for detection of a removable cap on an ultrasound probe |
| US8986224B2 (en) | 2012-07-20 | 2015-03-24 | DePuy Synthes Products, LLC | Guidewire with highly flexible tip |
| EP2916744B1 (en) | 2012-11-09 | 2020-05-20 | St. Jude Medical, Cardiology Division, Inc. | Devices for delivering vascular implants |
| US9522070B2 (en) | 2013-03-07 | 2016-12-20 | Interventional Spine, Inc. | Intervertebral implant |
| JP2015137428A (en) * | 2014-01-20 | 2015-07-30 | 朝日インテック株式会社 | Twisted wire and guide wire using the same |
| CN105979868B (en) | 2014-02-06 | 2020-03-10 | C·R·巴德股份有限公司 | Systems and methods for guidance and placement of intravascular devices |
| US10806905B2 (en) * | 2014-08-05 | 2020-10-20 | Cardiovascular Systems, Inc. | Reformable guidewire tip |
| US10973584B2 (en) | 2015-01-19 | 2021-04-13 | Bard Access Systems, Inc. | Device and method for vascular access |
| US11426290B2 (en) | 2015-03-06 | 2022-08-30 | DePuy Synthes Products, Inc. | Expandable intervertebral implant, system, kit and method |
| US10349890B2 (en) | 2015-06-26 | 2019-07-16 | C. R. Bard, Inc. | Connector interface for ECG-based catheter positioning system |
| US10596353B2 (en) * | 2015-10-15 | 2020-03-24 | MRI Interventions, Inc. | MRI-compatible guidewire |
| US11000207B2 (en) | 2016-01-29 | 2021-05-11 | C. R. Bard, Inc. | Multiple coil system for tracking a medical device |
| GB2549524B (en) * | 2016-04-21 | 2022-05-18 | Cambridge Univ Hospitals Nhs Foundation Trust | Apparatus and method for the treatment of defects internal of the body |
| US11596522B2 (en) | 2016-06-28 | 2023-03-07 | Eit Emerging Implant Technologies Gmbh | Expandable and angularly adjustable intervertebral cages with articulating joint |
| US11510788B2 (en) | 2016-06-28 | 2022-11-29 | Eit Emerging Implant Technologies Gmbh | Expandable, angularly adjustable intervertebral cages |
| WO2018174241A1 (en) * | 2017-03-24 | 2018-09-27 | 朝日インテック株式会社 | Dilator |
| US10398563B2 (en) | 2017-05-08 | 2019-09-03 | Medos International Sarl | Expandable cage |
| US11344424B2 (en) | 2017-06-14 | 2022-05-31 | Medos International Sarl | Expandable intervertebral implant and related methods |
| KR20200028450A (en) * | 2017-09-30 | 2020-03-16 | 아사히 인텍크 가부시키가이샤 | Guide wire |
| US10992079B2 (en) | 2018-10-16 | 2021-04-27 | Bard Access Systems, Inc. | Safety-equipped connection systems and methods thereof for establishing electrical connections |
| US11446156B2 (en) | 2018-10-25 | 2022-09-20 | Medos International Sarl | Expandable intervertebral implant, inserter instrument, and related methods |
| US20210220605A1 (en) * | 2020-01-21 | 2021-07-22 | Becton, Dickinson And Company | Tubular instrument and related devices and methods |
| US11426286B2 (en) | 2020-03-06 | 2022-08-30 | Eit Emerging Implant Technologies Gmbh | Expandable intervertebral implant |
| US20210393924A1 (en) * | 2020-06-19 | 2021-12-23 | Becton, Dickinson And Company | Vascular access instrument and related devices and methods |
| CN112641484A (en) * | 2020-12-31 | 2021-04-13 | 微创神通医疗科技（上海）有限公司 | Embolism material and preparation method thereof |
| US11850160B2 (en) | 2021-03-26 | 2023-12-26 | Medos International Sarl | Expandable lordotic intervertebral fusion cage |
| US11752009B2 (en) | 2021-04-06 | 2023-09-12 | Medos International Sarl | Expandable intervertebral fusion cage |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR440731A (en) * | 1912-02-28 | 1912-07-19 | Louis Marie Clement Charnaux | Probe or armed cannula for explorations and hygienic and medical applications |
| US3612058A (en) * | 1968-04-17 | 1971-10-12 | Electro Catheter Corp | Catheter stylets |
| US3757768A (en) * | 1972-04-07 | 1973-09-11 | Medical Evaluation Devices And | Manipulable spring guide-catheter and tube for intravenous feeding |
| US3922378A (en) * | 1972-08-04 | 1975-11-25 | Medical Evaluation Devices & I | Fluorinated hydrocarbon coating method |
| EP0247371A1 (en) * | 1986-05-23 | 1987-12-02 | Sarcem Sa | Catheter guide |
| US4763647A (en) * | 1987-01-06 | 1988-08-16 | C. R. Bard, Inc. | Dual coil steerable guidewire |
| US4815478A (en) * | 1987-02-17 | 1989-03-28 | Medtronic Versaflex, Inc. | Steerable guidewire with deflectable tip |
| US5154705A (en) * | 1987-09-30 | 1992-10-13 | Lake Region Manufacturing Co., Inc. | Hollow lumen cable apparatus |
| US5165421A (en) * | 1987-09-30 | 1992-11-24 | Lake Region Manufacturing Co., Inc. | Hollow lumen cable apparatus |
| EP0313836A3 (en) * | 1987-09-30 | 1991-01-23 | Advanced Cardiovascular Systems, Inc. | Pressure monitoring guidewire |
| US4932419A (en) * | 1988-03-21 | 1990-06-12 | Boston Scientific Corporation | Multi-filar, cross-wound coil for medical devices |
| US4917102A (en) * | 1988-09-14 | 1990-04-17 | Advanced Cardiovascular Systems, Inc. | Guidewire assembly with steerable adjustable tip |
| US5211636A (en) * | 1990-10-31 | 1993-05-18 | Lake Region Manufacturing Co., Inc. | Steerable infusion guide wire |
-
1990
- 1990-10-31 US US07/607,454 patent/US5211636A/en not_active Expired - Lifetime
-
1991
- 1991-10-28 EP EP92900016A patent/EP0509084B1/en not_active Expired - Lifetime
- 1991-10-28 WO PCT/US1991/008012 patent/WO1992007594A1/en active IP Right Grant
- 1991-10-28 CA CA2072580A patent/CA2072580A1/en not_active Abandoned
- 1991-10-28 DE DE69128710T patent/DE69128710T2/en not_active Expired - Fee Related
-
1993
- 1993-05-14 US US08/062,441 patent/US5376083A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5211636A (en) | 1993-05-18 |
| US5376083A (en) | 1994-12-27 |
| EP0509084A4 (en) | 1993-04-14 |
| DE69128710T2 (en) | 1998-07-16 |
| DE69128710D1 (en) | 1998-02-19 |
| EP0509084B1 (en) | 1998-01-14 |
| EP0509084A1 (en) | 1992-10-21 |
| WO1992007594A1 (en) | 1992-05-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2072580A1 (en) | Steerable infusion guide wire | |
| US6450987B1 (en) | Collapsible guidewire lumen | |
| EP2903682B1 (en) | Overmolded medical connector tubing and method | |
| US6450948B1 (en) | Deflecting tip for surgical cannula | |
| EP1849409B1 (en) | Sensor and guidewire assembly | |
| US7635347B2 (en) | Catheter with multilayer tube | |
| US20070255145A1 (en) | Sensor and guide wire assembly | |
| US7641757B2 (en) | Method of making a tubular body for a catheter, sheath or lead | |
| US6027477A (en) | Catheter with multilayer tube | |
| US20140094844A1 (en) | Catheter Markers | |
| WO2005084743A1 (en) | Occlusion balloon catheter with longitudinally expandable balloon | |
| US4784648A (en) | Infiltration indicator and alarm | |
| JP2002515769A (en) | Injection guidewire with fixed core wire and flexible radiopaque markers | |
| CA2162616A1 (en) | Catheter with dual round lumens | |
| EP0420486B1 (en) | Small diameter dilatation catheter having wire reinforced coaxial tubular body | |
| US20180256861A1 (en) | Guidewires with Variable Rigidity | |
| US8043278B2 (en) | Medical devices including aerated adhesive bonds and methods of forming the same | |
| US20050283179A1 (en) | Introducer sheath | |
| US6497841B1 (en) | Prevention of electrical discharges in polymeric heat exchangers | |
| US20240123192A1 (en) | Wire lock for medical devices | |
| JP6388316B2 (en) | Balloon catheter | |
| EP1060759A1 (en) | Medical balloon catheter having an inflation tube with a polyetherimide segment | |
| JP2008161631A (en) | Balloon catheter | |
| DE20303373U1 (en) | Infiltration catheter set comprises a plastic catheter which has a closed distal end provided with at least one group of lateral holes with identical or nearly identical cross sections |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |