CA2082367C - Stent for transluminal implantation - Google Patents
Stent for transluminal implantation Download PDFInfo
- Publication number
- CA2082367C CA2082367C CA2082367A CA2082367A CA2082367C CA 2082367 C CA2082367 C CA 2082367C CA 2082367 A CA2082367 A CA 2082367A CA 2082367 A CA2082367 A CA 2082367A CA 2082367 C CA2082367 C CA 2082367C
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- cylindrical
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- stent
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2002/828—Means for connecting a plurality of stents allowing flexibility of the whole structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
Abstract
The present invention relates to a stent consisting in the alternate juxtaposition of axially rigid cylindrical parts and at least one axially flexible cylindrical part ; said stent comprising two axially rigid cylindrical parts at its two ends ; said axially rigid cylindrical parts being adapted to expand radially in plastic manner and said axially flexible cylindrical part or parts being adapted to expand radially in elastic manner.
Description
STEBlTf FOR T~BANSLIJ~iIPIAL I~P!_AfffA'TIOP!
The present invention re7.ates to new scents for trans-luminal implantation and in particular new vascular stems.
05 Stents For transluminal implantation (also called "expandable intraluminal graft") have been developed these last few years. They are metallic supports which are inserted into a part of the human body, (such as the bile ducts, the urinary system, the digestive tube, ,..) and notably by percutaneous route, inside the blood vessels, generally the arteries (in which case they are called vascular stems). Said supports are adapted to expand radially. They are inserted while they have a first diameter (dl) and implanted, in the desired area, for example inside the vessel, and expanded in situ, until they reach a second diameter (d2:d2 > d1). An angiaplasty balloon, associated to a catheter; can be used to expand them radially.
Several types of scents are known, and in particular so-called "flexible'° scents, such as those described in Pat~nt Applications FR-A-2 525 896 and EP-A-0 183 372 and so-called °rigid" stents; such as those described in Patents US-A-4 739 762 and US-A-4 776 337 or in Patent Applications EP-A-0 221 570 and EP-A-0 364 787.
The present invention proposes a novel type of scents, which could be called "mixed" since they combine flexible parts with rigid parts. The combination according to the invention of flexible parts and rigid parts :in the structure of a scent, is not any kind of combination.
The stent for transluminal implantation, according to the present inventa.on, consists in the alternate juxtaposition of axially rigid cylindrical parts and at least one axially flexible cylindrical part; said scent comprising axially rigid cylindrical parts at its two ends; said axially rigid cylindrical parts being capable of expanding radially in plastic manner, while said axially flexible cylindrical part or parts is or are adapted to expand radially in elastic manner.
The present invention re7.ates to new scents for trans-luminal implantation and in particular new vascular stems.
05 Stents For transluminal implantation (also called "expandable intraluminal graft") have been developed these last few years. They are metallic supports which are inserted into a part of the human body, (such as the bile ducts, the urinary system, the digestive tube, ,..) and notably by percutaneous route, inside the blood vessels, generally the arteries (in which case they are called vascular stems). Said supports are adapted to expand radially. They are inserted while they have a first diameter (dl) and implanted, in the desired area, for example inside the vessel, and expanded in situ, until they reach a second diameter (d2:d2 > d1). An angiaplasty balloon, associated to a catheter; can be used to expand them radially.
Several types of scents are known, and in particular so-called "flexible'° scents, such as those described in Pat~nt Applications FR-A-2 525 896 and EP-A-0 183 372 and so-called °rigid" stents; such as those described in Patents US-A-4 739 762 and US-A-4 776 337 or in Patent Applications EP-A-0 221 570 and EP-A-0 364 787.
The present invention proposes a novel type of scents, which could be called "mixed" since they combine flexible parts with rigid parts. The combination according to the invention of flexible parts and rigid parts :in the structure of a scent, is not any kind of combination.
The stent for transluminal implantation, according to the present inventa.on, consists in the alternate juxtaposition of axially rigid cylindrical parts and at least one axially flexible cylindrical part; said scent comprising axially rigid cylindrical parts at its two ends; said axially rigid cylindrical parts being capable of expanding radially in plastic manner, while said axially flexible cylindrical part or parts is or are adapted to expand radially in elastic manner.
2 2os23s7 The alternate juxtaposition of the flexible parts and of the rigid parts is such that there are always:
- one axially rigid part at each end of the stent;
- two axially rigid parts on either side of an axially 05 flexible part.
Such an arrangement enables the stents according to the invention to fasten securely to the walls of the parts of the human body in which they are implanted and minimizes the risk of disturbances in the flow of the fluids circulating in said parts of the human body.
The stents according to the invention can exist in many variants. Indeed, the number of alternations of rigid parts and flexible part or parts can be varied.
It is possible to have one flexible part between two rigid end parts or several flexible parts and at least one intermediate rigid part between two rigid end parts.
According to two preferred variants of the invention, the structures of the stents follow the sequences indicated hereunder:
1) rigid end part - flexible part - rigid end part R - F - R
2) rigid end part - flexible part - intermediate rigid part -flexible part - rigid end part R - F - R' - F - R
For reasons of symmetry of deformation and of automatic production, the rigid intermediate parts are preferably identical to the rigid end parts (R=R'). This however is not an obligation.
In a general way and for the reasons given hereinabove, the stents according to the invention advantageously have rigid parts (end part and intermediate part or parts) which are all identical as well as equally identical flexible parts. This, nevertheless, does not exclude stents of more asymmetrical structure from the scope of the invention.
Depending on the total length and on the axial flexibility required for a stent according to the invention, it is possible to vary - the intrinsic characteristics of said rigid and flexible parts, notably their length, and - the number of alternations (rigid part/flexible part).
The invention therefore proposes "articulated" stents, of 05 modulable length and axial flexibility.
The flexible part or parts and the rigid parts of said stents are joined together by welding.
They must therefore be made from materials which can be welded together. It is moreover obvious that such materials have to be biocompatible, and each one should have the required mechanical properties (elasticity for the flexible part, plasticity for the rigid part).
For the rigid part, it is recommended to use stainless steel (and in particular of 316 L type) or titanium (in particular of T 35 of T 40 type). These materials have, in the annealed state, an equivalent and wide enough plasticity range. Any other biocompatible metal (or metal alloy) with similar mechanical properties can also be used.
One or more flexible parts in titanium which shows good elastic properties, such as the T 60 type, are advantageously combined with rigid parts in titanium. Similarly, one or more flexible parts in a stainless steel which has the required elasticity and which may or may not have undergone suitable thermal and/or mechanical treatments, are advantageously combined with rigid parts in stainless steel.
Whatever the case, the axially flexible parts which are liable to expand radially in elastic manner are parts which expand radially while keeping the material of which they are made within its elastic deformation range.
As indicated hereinabove, the stents according to the invention always have rigid ends. The can also include intermediate rigid parts in their structure. Said rigid intermediate or end - parts - help the stent to be positioned, and in particular, once expanded, they ensure its anchoring, whatever happens.
208236?
Said anchoring is advantageously improved by giving to said rigid parts shapes such that their ends "curl up" during radial expansion. 8y deforming so - outward opening -, said ends sink slightly into the wall of the parts of the body where the U5 stent is implanted, hence improving the anchoring. Such improved anchoring makes it possible to minimize the turbulences, inherent to the presence of the stent, in the blood flow for example, if the stent is implanted in a blood vessel.
Said axially rigid parts of the stents according to the invention can be given several shapes; shapes which, when produced in the adequate material, allow the expected radial expansion and induces the aforementioned "curling up".
For example, said axially rigid cylindrical parts can consist in tubes, along the generating lines of which are regularly distributed "slots" and "half-slots"; said "half-slots" being split and issuing into the ends of said tubes, thus creating flanges on which the axially flexible cylindrical parts are advantageously fixed.
Said flanges - T-shaped ends - deform outwardly during the expansion and are advantageously used for interlocking the flexible part or parts and the rigid parts. They ensure, by their very shape and deformation, an optimum impacting of the stent in the wall of the parts of the body where they are implanted. They offer a safe bearing surface and tend to sink into said wall.
The axially rigid cylindrical parts of the stents according to the invention can therefore consist in tubes along the generating lines of which slots have been cut in. The diameter of said tubes is of course the diameter set for the stent, before radial expansion.
The slots made in said tubes are particularly intended for minimizing the covering rate of the wall of the parts of the body in which they are implanted and for allowing radial expansion.
According to a first variant, a full slot - stretching along virtually the whole generating line of the tube - can be provided alternately v~ith a set of two half-slots, separated by a 20823~'~
metal strip; said two half-slots being split so as to issue onto the ends of the tube and to create flanges According to a second variant, and in particular to obtain longer rigid parts, it is possible to provide alternately:
05 - two full slots along a generating line, and - a set of two "half-slots" separated by one full slot along another generating line, the end parts of said half-slots being always split to allow expansion and to form the flanges.
Also, in order to obtain longer rigid parts, it is possible to arrange for the aforesaid variant, to be provided with longer slots.
Said slots and "half-slots" are regularly distributed on the periphery of the tube; this in order to obtain a homogeneous deformation throughout the radial expansion.
For said deformation to be perfectly homogeneous, the dimensions and distribution of the slots cut into the tube will be advantageously optimized, so that all the (remaining) metallic parts of said tubes have substantially the same width (e N e'~ a").
Said metallic parts of said tube consist in:
- the longitudinal strips between two successive sets of slots cut along two generating lines;
- the uncut parts between two slots along the same generating line;
- the uncut parts between the end of the tube and the split or non-split ends of said slots.
Moreover, according to a preferred variant of the invention, all the slots cut into the tube have rounded ends, and no sharp angles. In this way, any risks of incipient cracks, liable to cause splits during expansion, are avoided.
Said slots are advantageously in the form of rectangles, which are closed, widthwise, by two half- circles, of diameter equal to their widths ( ), Such slots deform under expansion in order to create" losenges", truncated along their larger diagonal .
The axially rigid cylindrical parts of the stents according to the invention are produced from metallic tubes in which the adequate slots have been cut.
Their covering rate after expansion, should be less than 05 20%. This figure is a compromise. Obviously, there has to be enough material for the stent to act as a support but not too much for it not to become uncomfortable, in particular, it should not create a risk of thrombosis inside a blood vessel.
Concerning the axially flexible cylindrical parts, these, as already indicated, are always inserted, in the structure of the stents according to the invention, between two axially rigid cylindrical parts. They are the ones which confer to said stents the axial flexibility They advantageously consist in a wire meshing, each wire being, by its two ends, welded to the axially rigid cylindrical parts - surrounding the axially flexible cylindrical parts - close to a knot of said meshing.
All the wire ends of the flexible meshing part are fixed to the rigid ends. This preventing the meshing from "coming undone", and avoiding the existence of loose wires, which would risk either to cause an injury to those parts of the human body where the stent is implanted, or on the contrary to float about inside said parts and in doing so, create dangerous turbulences.
The ends of the flexible parts - supported under expansion by the rigid parts - are thus stabilized.
The welded connection is performed close to a point to where the meshing wires converge; this in order to reduce to a minimum, the stresses exerted on the welding during expansion.
As a result, the length of the flexible parts can be adjusted to within half-a-mesh. The length of a flexible part between two rigid parts obviously ranges between a minimum length, necessary for obtaining the required elasticity and a maximum length beyond which a risk of the median zone of said flexible part collapsing, is liable to occur.
208236?
Advantageously, the wire meshing constituting the flexible parts of the stents according to the invention, is not any type of meshing.
The different flexible and rigid parts of said stents, 05 which are radially expandable, are in fact expanded in situ inside a blood vessel or any other part of the human body - under the action of an expandable balloon. Such a balloon is made up from a woven structure. In particular, it is possible to use one in polyurethane associated to a dilatation catheter.
Then, the characteristics of the meshes constituting the flexible parts of the stents according to the invention will be, advantageously, placed in coincidence with the meshes of the woven structure of said expandable balloon. By mesh characteristics are meant - the natural angle of slope (before expansion), - the aperture angle (after expansion); angles measured in relation to the longitudinal axis of the assembly;
- the behavior under expansion.
Said coincidence ensures a synchronous axial displacement between the balloon and the stent, during expansion, thereby eliminating any relative sliding of one with respect to the other.
It also guarantees the absence of all unwanted axial deformation when the stent is inserted in position.
Therefore, the axially flexible cylindrical parts of the stents according to the invention, advantageously consist in a metallic wire meshing spreading helically from one axially rigid cyclindrical part to the next axially rigid cylindrical part.
The axially flexible cylindrical parts covering rate is generally around that of the axially rigid cylindrical parts; it is below 20% and preferably around 15%.
The wires of the flexible parts are welded to the rigid parts, in order to, as indicated hereinabove, reduce to a minimum the stresses and the extra thickness at their level.
Advantageously, the weldings are located in the least deformable zone of the flanges constituting the ends of the rigid parts. They a are made on the outer parts of said flanges.
According to a preferred variant of the invention, the stent comprises ;
- axially rigid cylindrical parts, which consists in 05 tubes along the generating lines of which are regularly distributed slots and "half-slots", said "half-slots", which are split, issuing onto the ends of said tubes and, in doing so, creating flanges;
- at least one axially flexible cylindrical part, which consists in a wire meshing; the wires of said meshing being, in the vicinity of a knot thereof, welded in pairs, one at each end of said flanges, one forming a right-hand helical thread line, the other forming a left-hand helical thread line.
The invention will now be described with reference to the appended figures 1 to 4.
Figure 1 is a perspective view of a stent according to the invention, non-expanded.
Figure 2 is a perspective view of the same stent, expanded.
Figure 3 is a partial front view of a flexible part/rigid part welding zone of the stent according to Figure 1 (in non expanded condition).
Figure 4 shows the same zone, in expanded condition.
Said figures show a stent comprising an axially flexible cylindrical part (2) between two axially rigid cylindrical parts (1, 1'). Said rigid parts (1, 1') comprise slots (3) and "half-slots" (4), split in (5).
In (6) are shown the flanges created by such slots (3 and 4). All said slots have rounded ends. More particularly, Figure 3 shows that the solid metallic parts of the tubes, constituting the rigid ends of the stent, all have substantially the same width:
e~e'~.e"
The axially flexible cylindrical part (2) is a meshing of wires (7) of cylindrical section. Said wires are criss-crossed to form knots (a). They are welded close to said knots (8), in pairs, on the ends of the flanges (6) of the rigid parts (1, 1').
208236?
An example of the possible dimension of such a stent is given hereunder:
- length of the rigid end parts : about 8 mm - length of the flexible median part: between 7 and 21 mm 05 - initial diameter : 3 mm - diameter after expansion : 9 mm.
Said rigid end parts comprise 8 full slots on their periphery (8 "losenges" after expansion).
The uncut metallic parts - which are left after the slats have been cut - of said rigid end parts have a rectangular cross-section (between about 0.2 x 0.15 and 0.3 x 0.2 mm, depending on the width of the slots and on the thickness of the tube).
Such rigid parts have a covering rate less than 20% after expansion.
Said median flexible part is constituted of wires of diameter between about 0.15 and 0.20 mm. Given the number of full slots of the rigid end parts and consequently the number of flanges (8), on which are welded said wires, the meshing is constituted by the criss-crossing of 8 wires forming right-hand helical thread lines with 8 wires forming left-hand helical thread lines.
Depending on the length wanted for said flexible median part (between 7 and 21 mm), said wires make a quarter or three-quarters of a turn. The angle of said wires, measured with respect to the axis of the whole assembly is about 15° before expansion (preangularity), and 45° after expansion.
Such a flexible part has a covering rate around 15%.
i
- one axially rigid part at each end of the stent;
- two axially rigid parts on either side of an axially 05 flexible part.
Such an arrangement enables the stents according to the invention to fasten securely to the walls of the parts of the human body in which they are implanted and minimizes the risk of disturbances in the flow of the fluids circulating in said parts of the human body.
The stents according to the invention can exist in many variants. Indeed, the number of alternations of rigid parts and flexible part or parts can be varied.
It is possible to have one flexible part between two rigid end parts or several flexible parts and at least one intermediate rigid part between two rigid end parts.
According to two preferred variants of the invention, the structures of the stents follow the sequences indicated hereunder:
1) rigid end part - flexible part - rigid end part R - F - R
2) rigid end part - flexible part - intermediate rigid part -flexible part - rigid end part R - F - R' - F - R
For reasons of symmetry of deformation and of automatic production, the rigid intermediate parts are preferably identical to the rigid end parts (R=R'). This however is not an obligation.
In a general way and for the reasons given hereinabove, the stents according to the invention advantageously have rigid parts (end part and intermediate part or parts) which are all identical as well as equally identical flexible parts. This, nevertheless, does not exclude stents of more asymmetrical structure from the scope of the invention.
Depending on the total length and on the axial flexibility required for a stent according to the invention, it is possible to vary - the intrinsic characteristics of said rigid and flexible parts, notably their length, and - the number of alternations (rigid part/flexible part).
The invention therefore proposes "articulated" stents, of 05 modulable length and axial flexibility.
The flexible part or parts and the rigid parts of said stents are joined together by welding.
They must therefore be made from materials which can be welded together. It is moreover obvious that such materials have to be biocompatible, and each one should have the required mechanical properties (elasticity for the flexible part, plasticity for the rigid part).
For the rigid part, it is recommended to use stainless steel (and in particular of 316 L type) or titanium (in particular of T 35 of T 40 type). These materials have, in the annealed state, an equivalent and wide enough plasticity range. Any other biocompatible metal (or metal alloy) with similar mechanical properties can also be used.
One or more flexible parts in titanium which shows good elastic properties, such as the T 60 type, are advantageously combined with rigid parts in titanium. Similarly, one or more flexible parts in a stainless steel which has the required elasticity and which may or may not have undergone suitable thermal and/or mechanical treatments, are advantageously combined with rigid parts in stainless steel.
Whatever the case, the axially flexible parts which are liable to expand radially in elastic manner are parts which expand radially while keeping the material of which they are made within its elastic deformation range.
As indicated hereinabove, the stents according to the invention always have rigid ends. The can also include intermediate rigid parts in their structure. Said rigid intermediate or end - parts - help the stent to be positioned, and in particular, once expanded, they ensure its anchoring, whatever happens.
208236?
Said anchoring is advantageously improved by giving to said rigid parts shapes such that their ends "curl up" during radial expansion. 8y deforming so - outward opening -, said ends sink slightly into the wall of the parts of the body where the U5 stent is implanted, hence improving the anchoring. Such improved anchoring makes it possible to minimize the turbulences, inherent to the presence of the stent, in the blood flow for example, if the stent is implanted in a blood vessel.
Said axially rigid parts of the stents according to the invention can be given several shapes; shapes which, when produced in the adequate material, allow the expected radial expansion and induces the aforementioned "curling up".
For example, said axially rigid cylindrical parts can consist in tubes, along the generating lines of which are regularly distributed "slots" and "half-slots"; said "half-slots" being split and issuing into the ends of said tubes, thus creating flanges on which the axially flexible cylindrical parts are advantageously fixed.
Said flanges - T-shaped ends - deform outwardly during the expansion and are advantageously used for interlocking the flexible part or parts and the rigid parts. They ensure, by their very shape and deformation, an optimum impacting of the stent in the wall of the parts of the body where they are implanted. They offer a safe bearing surface and tend to sink into said wall.
The axially rigid cylindrical parts of the stents according to the invention can therefore consist in tubes along the generating lines of which slots have been cut in. The diameter of said tubes is of course the diameter set for the stent, before radial expansion.
The slots made in said tubes are particularly intended for minimizing the covering rate of the wall of the parts of the body in which they are implanted and for allowing radial expansion.
According to a first variant, a full slot - stretching along virtually the whole generating line of the tube - can be provided alternately v~ith a set of two half-slots, separated by a 20823~'~
metal strip; said two half-slots being split so as to issue onto the ends of the tube and to create flanges According to a second variant, and in particular to obtain longer rigid parts, it is possible to provide alternately:
05 - two full slots along a generating line, and - a set of two "half-slots" separated by one full slot along another generating line, the end parts of said half-slots being always split to allow expansion and to form the flanges.
Also, in order to obtain longer rigid parts, it is possible to arrange for the aforesaid variant, to be provided with longer slots.
Said slots and "half-slots" are regularly distributed on the periphery of the tube; this in order to obtain a homogeneous deformation throughout the radial expansion.
For said deformation to be perfectly homogeneous, the dimensions and distribution of the slots cut into the tube will be advantageously optimized, so that all the (remaining) metallic parts of said tubes have substantially the same width (e N e'~ a").
Said metallic parts of said tube consist in:
- the longitudinal strips between two successive sets of slots cut along two generating lines;
- the uncut parts between two slots along the same generating line;
- the uncut parts between the end of the tube and the split or non-split ends of said slots.
Moreover, according to a preferred variant of the invention, all the slots cut into the tube have rounded ends, and no sharp angles. In this way, any risks of incipient cracks, liable to cause splits during expansion, are avoided.
Said slots are advantageously in the form of rectangles, which are closed, widthwise, by two half- circles, of diameter equal to their widths ( ), Such slots deform under expansion in order to create" losenges", truncated along their larger diagonal .
The axially rigid cylindrical parts of the stents according to the invention are produced from metallic tubes in which the adequate slots have been cut.
Their covering rate after expansion, should be less than 05 20%. This figure is a compromise. Obviously, there has to be enough material for the stent to act as a support but not too much for it not to become uncomfortable, in particular, it should not create a risk of thrombosis inside a blood vessel.
Concerning the axially flexible cylindrical parts, these, as already indicated, are always inserted, in the structure of the stents according to the invention, between two axially rigid cylindrical parts. They are the ones which confer to said stents the axial flexibility They advantageously consist in a wire meshing, each wire being, by its two ends, welded to the axially rigid cylindrical parts - surrounding the axially flexible cylindrical parts - close to a knot of said meshing.
All the wire ends of the flexible meshing part are fixed to the rigid ends. This preventing the meshing from "coming undone", and avoiding the existence of loose wires, which would risk either to cause an injury to those parts of the human body where the stent is implanted, or on the contrary to float about inside said parts and in doing so, create dangerous turbulences.
The ends of the flexible parts - supported under expansion by the rigid parts - are thus stabilized.
The welded connection is performed close to a point to where the meshing wires converge; this in order to reduce to a minimum, the stresses exerted on the welding during expansion.
As a result, the length of the flexible parts can be adjusted to within half-a-mesh. The length of a flexible part between two rigid parts obviously ranges between a minimum length, necessary for obtaining the required elasticity and a maximum length beyond which a risk of the median zone of said flexible part collapsing, is liable to occur.
208236?
Advantageously, the wire meshing constituting the flexible parts of the stents according to the invention, is not any type of meshing.
The different flexible and rigid parts of said stents, 05 which are radially expandable, are in fact expanded in situ inside a blood vessel or any other part of the human body - under the action of an expandable balloon. Such a balloon is made up from a woven structure. In particular, it is possible to use one in polyurethane associated to a dilatation catheter.
Then, the characteristics of the meshes constituting the flexible parts of the stents according to the invention will be, advantageously, placed in coincidence with the meshes of the woven structure of said expandable balloon. By mesh characteristics are meant - the natural angle of slope (before expansion), - the aperture angle (after expansion); angles measured in relation to the longitudinal axis of the assembly;
- the behavior under expansion.
Said coincidence ensures a synchronous axial displacement between the balloon and the stent, during expansion, thereby eliminating any relative sliding of one with respect to the other.
It also guarantees the absence of all unwanted axial deformation when the stent is inserted in position.
Therefore, the axially flexible cylindrical parts of the stents according to the invention, advantageously consist in a metallic wire meshing spreading helically from one axially rigid cyclindrical part to the next axially rigid cylindrical part.
The axially flexible cylindrical parts covering rate is generally around that of the axially rigid cylindrical parts; it is below 20% and preferably around 15%.
The wires of the flexible parts are welded to the rigid parts, in order to, as indicated hereinabove, reduce to a minimum the stresses and the extra thickness at their level.
Advantageously, the weldings are located in the least deformable zone of the flanges constituting the ends of the rigid parts. They a are made on the outer parts of said flanges.
According to a preferred variant of the invention, the stent comprises ;
- axially rigid cylindrical parts, which consists in 05 tubes along the generating lines of which are regularly distributed slots and "half-slots", said "half-slots", which are split, issuing onto the ends of said tubes and, in doing so, creating flanges;
- at least one axially flexible cylindrical part, which consists in a wire meshing; the wires of said meshing being, in the vicinity of a knot thereof, welded in pairs, one at each end of said flanges, one forming a right-hand helical thread line, the other forming a left-hand helical thread line.
The invention will now be described with reference to the appended figures 1 to 4.
Figure 1 is a perspective view of a stent according to the invention, non-expanded.
Figure 2 is a perspective view of the same stent, expanded.
Figure 3 is a partial front view of a flexible part/rigid part welding zone of the stent according to Figure 1 (in non expanded condition).
Figure 4 shows the same zone, in expanded condition.
Said figures show a stent comprising an axially flexible cylindrical part (2) between two axially rigid cylindrical parts (1, 1'). Said rigid parts (1, 1') comprise slots (3) and "half-slots" (4), split in (5).
In (6) are shown the flanges created by such slots (3 and 4). All said slots have rounded ends. More particularly, Figure 3 shows that the solid metallic parts of the tubes, constituting the rigid ends of the stent, all have substantially the same width:
e~e'~.e"
The axially flexible cylindrical part (2) is a meshing of wires (7) of cylindrical section. Said wires are criss-crossed to form knots (a). They are welded close to said knots (8), in pairs, on the ends of the flanges (6) of the rigid parts (1, 1').
208236?
An example of the possible dimension of such a stent is given hereunder:
- length of the rigid end parts : about 8 mm - length of the flexible median part: between 7 and 21 mm 05 - initial diameter : 3 mm - diameter after expansion : 9 mm.
Said rigid end parts comprise 8 full slots on their periphery (8 "losenges" after expansion).
The uncut metallic parts - which are left after the slats have been cut - of said rigid end parts have a rectangular cross-section (between about 0.2 x 0.15 and 0.3 x 0.2 mm, depending on the width of the slots and on the thickness of the tube).
Such rigid parts have a covering rate less than 20% after expansion.
Said median flexible part is constituted of wires of diameter between about 0.15 and 0.20 mm. Given the number of full slots of the rigid end parts and consequently the number of flanges (8), on which are welded said wires, the meshing is constituted by the criss-crossing of 8 wires forming right-hand helical thread lines with 8 wires forming left-hand helical thread lines.
Depending on the length wanted for said flexible median part (between 7 and 21 mm), said wires make a quarter or three-quarters of a turn. The angle of said wires, measured with respect to the axis of the whole assembly is about 15° before expansion (preangularity), and 45° after expansion.
Such a flexible part has a covering rate around 15%.
i
Claims (13)
1. Stent for transluminal implantation, characterized in that it comprises the alternate juxtaposition of non-longitudinally expansive cylindrical parts and at least one radially and longitudinally flexible cylindrical part; said stent comprising said non-longitudinally expansive cylindrical parts at its two ends; said non-longitudinally expansive cylindrical parts being adapted to expand radially and said flexible cylindrical part or parts comprising a radially and longitudinally distensible cylindrical mesh.
2. Stent according to claim 1, characterized in that it includes, between two non-longitudinally expansive cylindrical ends adapted to expand radially, a radially and longitudinally flexible cylindrical part adapted to expand in elastic manner.
3. Stent according to claim 1, characterized in that it includes at least one non-longitudinally expansive intermediate cylindrical part which is identical to said non-longitudinally expansive cylindrical end parts.
4. Stent according to claim 1, characterized in that said non-longitudinally expansive cylindrical parts and said radially and longitudinally flexible part or parts are fixed by welding.
5. Stent according to claim 1, characterized in that the ends of the non-longitudinally expansive cylindrical parts curl up during the radial expansion of said parts.
6. Stent according to claim 1, characterized in that said non-longitudinally expansive cylindrical parts comprises tubular members having a longitudinal axis, two ends and a surface, slots and half slots being cut regularly along said surface and being aligned with said longitudinal axis of said tubular members, said half slots being split and issuing into the ends of said tubular members, thus creating flanges. said flanges having ends on which the flexible cylindrical parts are fixed.
7. Stent according to claim 6, characterized in that the dimensions and distribution of said slots and half slots are such that the uncut metallic parts of said tubular members all have substantially the same width.
8. Stent according to claim 6, characterized in that said slots or half slots have rounded ends.
9. Stent according to claim 1, characterized in that said radially and longitudinally flexible cylindrical parts consist in a meshing of wires; each one of said wires being welded by its two ends to the non-longitudinally expansive cylindrical parts close to a knot of said meshing.
10. Stent according to claim 6, characterized in that:
- its radially and longitudinally flexible cylindrical parts consist in a meshing of wires, the wires of said meshing, close to a knot thereof, welded in pairs, one wire to each end of said flanges, one forming a right-hand helical thread line, and the other a left-hand helical thread line.
- its radially and longitudinally flexible cylindrical parts consist in a meshing of wires, the wires of said meshing, close to a knot thereof, welded in pairs, one wire to each end of said flanges, one forming a right-hand helical thread line, and the other a left-hand helical thread line.
11. A device for the implantation of a stent, comprising a stent according to claim 1, an angioplastic expandable balloon and a catheter, said expandable balloon being made of a second mesh of woven structure, said first mesh of said at least one radially and longitudinally flexible part having a first natural angle of slope, a first aperture angle, and a first behavior under expansion, said second mesh of said expandable balloon having a second natural angle of slope, a second aperture angle and a second behavior under expansion which coincide with said first natural angle of slope, said first aperture angle, and said first behavior under expansion.
12. Stent according to claim 1, wherein said non-longitudinally expansive cylindrical parts are capable of contracting longitudinally.
13. Stent according to claim 1, wherein said non-longitudinally expansive cylindrical parts have openings.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9113820A FR2683449A1 (en) | 1991-11-08 | 1991-11-08 | ENDOPROTHESIS FOR TRANSLUMINAL IMPLANTATION. |
| FR9113820 | 1991-11-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2082367A1 CA2082367A1 (en) | 1993-05-09 |
| CA2082367C true CA2082367C (en) | 2004-03-30 |
Family
ID=9418771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2082367A Expired - Fee Related CA2082367C (en) | 1991-11-08 | 1992-11-06 | Stent for transluminal implantation |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5383892A (en) |
| EP (1) | EP0541443B1 (en) |
| AT (1) | ATE133554T1 (en) |
| CA (1) | CA2082367C (en) |
| DE (1) | DE69208026T2 (en) |
| DK (1) | DK0541443T3 (en) |
| ES (1) | ES2085595T3 (en) |
| FR (1) | FR2683449A1 (en) |
Families Citing this family (518)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5876419A (en) * | 1976-10-02 | 1999-03-02 | Navius Corporation | Stent and method for making a stent |
| US5643314A (en) * | 1995-11-13 | 1997-07-01 | Navius Corporation | Self-expanding stent |
| US6344053B1 (en) * | 1993-12-22 | 2002-02-05 | Medtronic Ave, Inc. | Endovascular support device and method |
| CA2079417C (en) | 1991-10-28 | 2003-01-07 | Lilip Lau | Expandable stents and method of making same |
| US5316023A (en) | 1992-01-08 | 1994-05-31 | Expandable Grafts Partnership | Method for bilateral intra-aortic bypass |
| US5366473A (en) * | 1992-08-18 | 1994-11-22 | Ultrasonic Sensing And Monitoring Systems, Inc. | Method and apparatus for applying vascular grafts |
| US5843167A (en) * | 1993-04-22 | 1998-12-01 | C. R. Bard, Inc. | Method and apparatus for recapture of hooked endoprosthesis |
| US6685736B1 (en) | 1993-09-30 | 2004-02-03 | Endogad Research Pty Limited | Intraluminal graft |
| AU699556B2 (en) * | 1993-10-01 | 1998-12-10 | Juan C. Parodi | Method for repairing an abdominal aortic aneurysm |
| DE69419877T2 (en) * | 1993-11-04 | 1999-12-16 | Bard Inc C R | Fixed vascular prosthesis |
| US5607444A (en) * | 1993-12-02 | 1997-03-04 | Advanced Cardiovascular Systems, Inc. | Ostial stent for bifurcations |
| RU2089131C1 (en) * | 1993-12-28 | 1997-09-10 | Сергей Апполонович Пульнев | Stent-expander |
| US5609627A (en) * | 1994-02-09 | 1997-03-11 | Boston Scientific Technology, Inc. | Method for delivering a bifurcated endoluminal prosthesis |
| US6051020A (en) * | 1994-02-09 | 2000-04-18 | Boston Scientific Technology, Inc. | Bifurcated endoluminal prosthesis |
| US6039749A (en) | 1994-02-10 | 2000-03-21 | Endovascular Systems, Inc. | Method and apparatus for deploying non-circular stents and graftstent complexes |
| US5507769A (en) * | 1994-10-18 | 1996-04-16 | Stentco, Inc. | Method and apparatus for forming an endoluminal bifurcated graft |
| US5645560A (en) * | 1995-12-15 | 1997-07-08 | Cardiovascular Dynamics, Inc. | Fixed focal balloon for interactive angioplasty and stent implantation |
| WO1995023563A1 (en) * | 1994-03-04 | 1995-09-08 | Universite De Montreal | Endovascular hepatic prostheses |
| US5556413A (en) * | 1994-03-11 | 1996-09-17 | Advanced Cardiovascular Systems, Inc. | Coiled stent with locking ends |
| US6464722B2 (en) | 1994-03-17 | 2002-10-15 | Medinol, Ltd. | Flexible expandable stent |
| US5843120A (en) * | 1994-03-17 | 1998-12-01 | Medinol Ltd. | Flexible-expandable stent |
| US5733303A (en) * | 1994-03-17 | 1998-03-31 | Medinol Ltd. | Flexible expandable stent |
| US6461381B2 (en) | 1994-03-17 | 2002-10-08 | Medinol, Ltd. | Flexible expandable stent |
| US5449373A (en) | 1994-03-17 | 1995-09-12 | Medinol Ltd. | Articulated stent |
| WO1995031945A1 (en) * | 1994-05-19 | 1995-11-30 | Scimed Life Systems, Inc. | Improved tissue supporting devices |
| US5540701A (en) * | 1994-05-20 | 1996-07-30 | Hugh Sharkey | Passive fixation anastomosis method and device |
| EP1520557A3 (en) | 1994-06-08 | 2010-07-21 | Cardiovascular Concepts, Inc. | Apparatus and methods for endoluminal graft placement |
| US6123715A (en) | 1994-07-08 | 2000-09-26 | Amplatz; Curtis | Method of forming medical devices; intravascular occlusion devices |
| DE69529338T3 (en) * | 1994-07-08 | 2007-05-31 | Ev3 Inc., Plymouth | Intravascular filter device |
| US5609605A (en) * | 1994-08-25 | 1997-03-11 | Ethicon, Inc. | Combination arterial stent |
| US5836964A (en) | 1996-10-30 | 1998-11-17 | Medinol Ltd. | Stent fabrication method |
| JP3611578B2 (en) * | 1994-11-09 | 2005-01-19 | エンドテックス インターベンショナル システムズ，インコーポレイテッド | Delivery catheter and graft for the treatment of aneurysms |
| CA2163824C (en) * | 1994-11-28 | 2000-06-20 | Richard J. Saunders | Method and apparatus for direct laser cutting of metal stents |
| US5575818A (en) * | 1995-02-14 | 1996-11-19 | Corvita Corporation | Endovascular stent with locking ring |
| US7204848B1 (en) | 1995-03-01 | 2007-04-17 | Boston Scientific Scimed, Inc. | Longitudinally flexible expandable stent |
| US20070073384A1 (en) * | 1995-03-01 | 2007-03-29 | Boston Scientific Scimed, Inc. | Longitudinally flexible expandable stent |
| US6896696B2 (en) | 1998-11-20 | 2005-05-24 | Scimed Life Systems, Inc. | Flexible and expandable stent |
| DE69637527D1 (en) | 1995-03-01 | 2008-06-26 | Boston Scient Scimed Inc | Longitudinally flexible and expandable stent |
| US6818014B2 (en) | 1995-03-01 | 2004-11-16 | Scimed Life Systems, Inc. | Longitudinally flexible expandable stent |
| US5749851A (en) * | 1995-03-02 | 1998-05-12 | Scimed Life Systems, Inc. | Stent installation method using balloon catheter having stepped compliance curve |
| DE19508805C2 (en) * | 1995-03-06 | 2000-03-30 | Lutz Freitag | Stent for placement in a body tube with a flexible support structure made of at least two wires with different shape memory functions |
| US6451047B2 (en) | 1995-03-10 | 2002-09-17 | Impra, Inc. | Encapsulated intraluminal stent-graft and methods of making same |
| US6264684B1 (en) | 1995-03-10 | 2001-07-24 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Helically supported graft |
| US6579314B1 (en) * | 1995-03-10 | 2003-06-17 | C.R. Bard, Inc. | Covered stent with encapsulated ends |
| BE1009277A3 (en) | 1995-04-12 | 1997-01-07 | Corvita Europ | Guardian self-expandable medical device introduced in cavite body, and method of preparation. |
| BE1009278A3 (en) * | 1995-04-12 | 1997-01-07 | Corvita Europ | Guardian self-expandable medical device introduced in cavite body, and medical device with a stake as. |
| EP1669043A3 (en) * | 1995-04-26 | 2006-06-28 | Medinol Ltd. | Articulated stent |
| KR100325267B1 (en) * | 1995-04-26 | 2003-10-11 | 메디놀 리미티드 | Articulating stent |
| US5591198A (en) * | 1995-04-27 | 1997-01-07 | Medtronic, Inc. | Multiple sinusoidal wave configuration stent |
| US6602281B1 (en) * | 1995-06-05 | 2003-08-05 | Avantec Vascular Corporation | Radially expansible vessel scaffold having beams and expansion joints |
| US5704910A (en) * | 1995-06-05 | 1998-01-06 | Nephros Therapeutics, Inc. | Implantable device and use therefor |
| US5700269A (en) * | 1995-06-06 | 1997-12-23 | Corvita Corporation | Endoluminal prosthesis deployment device for use with prostheses of variable length and having retraction ability |
| KR100262837B1 (en) | 1995-06-06 | 2000-09-01 | 스피겔 알렌 제이 | Endovascular measuring apparatus, loading and deployment means |
| US6616675B1 (en) * | 1996-02-02 | 2003-09-09 | Transvascular, Inc. | Methods and apparatus for connecting openings formed in adjacent blood vessels or other anatomical structures |
| US5830222A (en) | 1995-10-13 | 1998-11-03 | Transvascular, Inc. | Device, system and method for intersititial transvascular intervention |
| US5776161A (en) | 1995-10-16 | 1998-07-07 | Instent, Inc. | Medical stents, apparatus and method for making same |
| US6287336B1 (en) | 1995-10-16 | 2001-09-11 | Medtronic, Inc. | Variable flexibility stent |
| US5628788A (en) * | 1995-11-07 | 1997-05-13 | Corvita Corporation | Self-expanding endoluminal stent-graft |
| US6348066B1 (en) * | 1995-11-07 | 2002-02-19 | Corvita Corporation | Modular endoluminal stent-grafts and methods for their use |
| US5735872A (en) * | 1995-11-13 | 1998-04-07 | Navius Corporation | Stent |
| US5593417A (en) * | 1995-11-27 | 1997-01-14 | Rhodes; Valentine J. | Intravascular stent with secure mounting means |
| AT404557B (en) * | 1995-12-11 | 1998-12-28 | Hassan Ali Dr | Device (stent) for stabilizing stenosed or angioplastically treated partial regions of a vessel wall |
| WO1997021399A1 (en) | 1995-12-11 | 1997-06-19 | Ali Hassan | Device for stabilising angioplastically treated partial regions of a vessel wall (stent) |
| US6719782B1 (en) | 1996-01-04 | 2004-04-13 | Endovascular Technologies, Inc. | Flat wire stent |
| US6203569B1 (en) * | 1996-01-04 | 2001-03-20 | Bandula Wijay | Flexible stent |
| DE69735530T2 (en) * | 1996-01-04 | 2006-08-17 | Chuter, Timothy A.M. Dr., Atherton | FLAT WIRE STENT |
| US6168622B1 (en) | 1996-01-24 | 2001-01-02 | Microvena Corporation | Method and apparatus for occluding aneurysms |
| US5980553A (en) | 1996-12-20 | 1999-11-09 | Cordis Corporation | Axially flexible stent |
| US6258116B1 (en) * | 1996-01-26 | 2001-07-10 | Cordis Corporation | Bifurcated axially flexible stent |
| ATE247429T1 (en) | 1996-02-02 | 2003-09-15 | Transvascular Inc | SYSTEM FOR INTERSTITIAL TRANSVASCULAR SURGICAL PROCEDURES |
| CA2248718A1 (en) | 1996-03-05 | 1997-09-12 | Divysio Solutions Ulc. | Expandable stent and method for delivery of same |
| CA2192520A1 (en) | 1996-03-05 | 1997-09-05 | Ian M. Penn | Expandable stent and method for delivery of same |
| US6796997B1 (en) | 1996-03-05 | 2004-09-28 | Evysio Medical Devices Ulc | Expandable stent |
| US5868780A (en) | 1996-03-22 | 1999-02-09 | Lashinski; Robert D. | Stents for supporting lumens in living tissue |
| CA2199890C (en) * | 1996-03-26 | 2002-02-05 | Leonard Pinchuk | Stents and stent-grafts having enhanced hoop strength and methods of making the same |
| AU727751B2 (en) * | 1996-04-10 | 2000-12-21 | Advanced Cardiovascular Systems Inc. | Stent having varied amounts of structural strength along its length |
| DE19614160A1 (en) * | 1996-04-10 | 1997-10-16 | Variomed Ag | Stent for transluminal implantation in hollow organs |
| NZ331269A (en) * | 1996-04-10 | 2000-01-28 | Advanced Cardiovascular System | Expandable stent, its structural strength varying along its length |
| US5833699A (en) * | 1996-04-10 | 1998-11-10 | Chuter; Timothy A. M. | Extending ribbon stent |
| US20040106985A1 (en) * | 1996-04-26 | 2004-06-03 | Jang G. David | Intravascular stent |
| US6235053B1 (en) * | 1998-02-02 | 2001-05-22 | G. David Jang | Tubular stent consists of chevron-shape expansion struts and contralaterally attached diagonal connectors |
| US5954743A (en) * | 1996-04-26 | 1999-09-21 | Jang; G. David | Intravascular stent |
| JP4636634B2 (en) | 1996-04-26 | 2011-02-23 | ボストン サイエンティフィック サイムド，インコーポレイテッド | Intravascular stent |
| US6241760B1 (en) * | 1996-04-26 | 2001-06-05 | G. David Jang | Intravascular stent |
| UA58485C2 (en) * | 1996-05-03 | 2003-08-15 | Медінол Лтд. | Method for manufacture of bifurcated stent (variants) and bifurcated stent (variants) |
| US6251133B1 (en) | 1996-05-03 | 2001-06-26 | Medinol Ltd. | Bifurcated stent with improved side branch aperture and method of making same |
| US7641685B2 (en) * | 1996-05-03 | 2010-01-05 | Medinol Ltd. | System and method for delivering a bifurcated stent |
| US6770092B2 (en) | 1996-05-03 | 2004-08-03 | Medinol Ltd. | Method of delivering a bifurcated stent |
| US6440165B1 (en) * | 1996-05-03 | 2002-08-27 | Medinol, Ltd. | Bifurcated stent with improved side branch aperture and method of making same |
| US6666883B1 (en) | 1996-06-06 | 2003-12-23 | Jacques Seguin | Endoprosthesis for vascular bifurcation |
| US5697971A (en) * | 1996-06-11 | 1997-12-16 | Fischell; Robert E. | Multi-cell stent with cells having differing characteristics |
| US5855596A (en) * | 1996-06-25 | 1999-01-05 | International Business Machines Corporation | Modular wire band stent |
| US5755781A (en) * | 1996-08-06 | 1998-05-26 | Iowa-India Investments Company Limited | Embodiments of multiple interconnected stents |
| US5911752A (en) * | 1996-09-13 | 1999-06-15 | Intratherapeutics, Inc. | Method for collapsing a stent |
| US5807404A (en) | 1996-09-19 | 1998-09-15 | Medinol Ltd. | Stent with variable features to optimize support and method of making such stent |
| AU768602B2 (en) * | 1996-09-19 | 2003-12-18 | Medinol Ltd | Stent with variable features to optimize support and method of making such stent |
| US20060173531A1 (en) * | 1996-09-19 | 2006-08-03 | Jacob Richter | Stent with variable features to optimize support and method of making such stent |
| US5989276A (en) * | 1996-11-08 | 1999-11-23 | Advanced Bypass Technologies, Inc. | Percutaneous bypass graft and securing system |
| US6432127B1 (en) | 1996-10-11 | 2002-08-13 | Transvascular, Inc. | Devices for forming and/or maintaining connections between adjacent anatomical conduits |
| US7591846B2 (en) * | 1996-11-04 | 2009-09-22 | Boston Scientific Scimed, Inc. | Methods for deploying stents in bifurcations |
| US6692483B2 (en) | 1996-11-04 | 2004-02-17 | Advanced Stent Technologies, Inc. | Catheter with attached flexible side sheath |
| AU4896797A (en) * | 1996-11-04 | 1998-05-29 | Davidson, Charles | Extendible stent apparatus and method for deploying the same |
| US6835203B1 (en) * | 1996-11-04 | 2004-12-28 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
| US6599316B2 (en) * | 1996-11-04 | 2003-07-29 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
| US7220275B2 (en) * | 1996-11-04 | 2007-05-22 | Advanced Stent Technologies, Inc. | Stent with protruding branch portion for bifurcated vessels |
| US8211167B2 (en) | 1999-12-06 | 2012-07-03 | Boston Scientific Scimed, Inc. | Method of using a catheter with attached flexible side sheath |
| US7341598B2 (en) | 1999-01-13 | 2008-03-11 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
| US6325826B1 (en) | 1998-01-14 | 2001-12-04 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
| WO1998020810A1 (en) | 1996-11-12 | 1998-05-22 | Medtronic, Inc. | Flexible, radially expansible luminal prostheses |
| US5860998A (en) * | 1996-11-25 | 1999-01-19 | C. R. Bard, Inc. | Deployment device for tubular expandable prosthesis |
| US6551350B1 (en) * | 1996-12-23 | 2003-04-22 | Gore Enterprise Holdings, Inc. | Kink resistant bifurcated prosthesis |
| US7959664B2 (en) | 1996-12-26 | 2011-06-14 | Medinol, Ltd. | Flat process of drug coating for stents |
| CA2278640C (en) | 1997-01-24 | 2007-12-11 | Petrus Antonius Besselink | Bistable spring construction for a stent and other medical apparatus |
| US8353948B2 (en) * | 1997-01-24 | 2013-01-15 | Celonova Stent, Inc. | Fracture-resistant helical stent incorporating bistable cells and methods of use |
| US8663311B2 (en) * | 1997-01-24 | 2014-03-04 | Celonova Stent, Inc. | Device comprising biodegradable bistable or multistable cells and methods of use |
| US6241757B1 (en) * | 1997-02-04 | 2001-06-05 | Solco Surgical Instrument Co., Ltd. | Stent for expanding body's lumen |
| US20040267350A1 (en) * | 2002-10-30 | 2004-12-30 | Roubin Gary S. | Non-foreshortening intraluminal prosthesis |
| US5827321A (en) * | 1997-02-07 | 1998-10-27 | Cornerstone Devices, Inc. | Non-Foreshortening intraluminal prosthesis |
| US7094249B1 (en) | 1997-03-06 | 2006-08-22 | Boston Scientific Scimed, Inc. | Distal protection device and method |
| US5814064A (en) * | 1997-03-06 | 1998-09-29 | Scimed Life Systems, Inc. | Distal protection device |
| US5911732A (en) * | 1997-03-10 | 1999-06-15 | Johnson & Johnson Interventional Systems, Co. | Articulated expandable intraluminal stent |
| US5817126A (en) * | 1997-03-17 | 1998-10-06 | Surface Genesis, Inc. | Compound stent |
| US5868783A (en) * | 1997-04-16 | 1999-02-09 | Numed, Inc. | Intravascular stent with limited axial shrinkage |
| WO1998047447A1 (en) * | 1997-04-23 | 1998-10-29 | Dubrul William R | Bifurcated stent and distal protection system |
| US6033433A (en) | 1997-04-25 | 2000-03-07 | Scimed Life Systems, Inc. | Stent configurations including spirals |
| US5741327A (en) * | 1997-05-06 | 1998-04-21 | Global Therapeutics, Inc. | Surgical stent featuring radiopaque markers |
| ATE336958T1 (en) † | 1997-05-07 | 2006-09-15 | Cordis Corp | INTRAVASCULAR STENT AND SYSTEM FOR INSERTING (OBSTRUCTION OF THE OSTIUM OF A VESSEL) |
| US6676682B1 (en) * | 1997-05-08 | 2004-01-13 | Scimed Life Systems, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
| US5911734A (en) * | 1997-05-08 | 1999-06-15 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
| DE29708879U1 (en) * | 1997-05-20 | 1997-07-31 | Jomed Implantate Gmbh | Coronary stent |
| US5836966A (en) | 1997-05-22 | 1998-11-17 | Scimed Life Systems, Inc. | Variable expansion force stent |
| US6409755B1 (en) * | 1997-05-29 | 2002-06-25 | Scimed Life Systems, Inc. | Balloon expandable stent with a self-expanding portion |
| US5913895A (en) * | 1997-06-02 | 1999-06-22 | Isostent, Inc. | Intravascular stent with enhanced rigidity strut members |
| US5746691A (en) | 1997-06-06 | 1998-05-05 | Global Therapeutics, Inc. | Method for polishing surgical stents |
| FR2765097B1 (en) * | 1997-06-25 | 1999-08-06 | Braun Celsa Sa | IMPLANT WITH VARIABLE CRUSHING RESISTANCE, IMPLANTABLE IN AN ANATOMICAL CONDUIT |
| ATE255859T1 (en) * | 1997-07-08 | 2003-12-15 | Evysio Medical Devices Ulc | EXPANDABLE STENT |
| US6070589A (en) | 1997-08-01 | 2000-06-06 | Teramed, Inc. | Methods for deploying bypass graft stents |
| IT1293690B1 (en) * | 1997-08-08 | 1999-03-08 | Sorin Biomedica Cardio Spa | ANGIOPLASTIC STENT, PARTICULARLY FOR THE TREATMENT OF AORTO-HOSPITAL AND HOSPITAL INJURIES. |
| US7955379B2 (en) | 1997-08-13 | 2011-06-07 | Abbott Cardiovascular Systems Inc. | Stent and catheter assembly and method for treating bifurcations |
| US6165195A (en) * | 1997-08-13 | 2000-12-26 | Advanced Cardiovascylar Systems, Inc. | Stent and catheter assembly and method for treating bifurcations |
| US6059822A (en) * | 1997-08-22 | 2000-05-09 | Uni-Cath Inc. | Stent with different mesh patterns |
| US6746476B1 (en) * | 1997-09-22 | 2004-06-08 | Cordis Corporation | Bifurcated axially flexible stent |
| DE69838256T2 (en) | 1997-09-24 | 2008-05-15 | Med Institute, Inc., West Lafayette | RADIAL EXPANDABLE STENT |
| US6066149A (en) * | 1997-09-30 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot treatment device with distal filter |
| US6224625B1 (en) | 1997-10-27 | 2001-05-01 | Iowa-India Investments Company Limited | Low profile highly expandable stent |
| US6309414B1 (en) * | 1997-11-04 | 2001-10-30 | Sorin Biomedica Cardio S.P.A. | Angioplasty stents |
| US6330884B1 (en) * | 1997-11-14 | 2001-12-18 | Transvascular, Inc. | Deformable scaffolding multicellular stent |
| US6165209A (en) * | 1997-12-15 | 2000-12-26 | Prolifix Medical, Inc. | Vascular stent for reduction of restenosis |
| US6342067B1 (en) | 1998-01-09 | 2002-01-29 | Nitinol Development Corporation | Intravascular stent having curved bridges for connecting adjacent hoops |
| US6179867B1 (en) * | 1998-01-16 | 2001-01-30 | Advanced Cardiovascular Systems, Inc. | Flexible stent and method of use |
| US6395019B2 (en) | 1998-02-09 | 2002-05-28 | Trivascular, Inc. | Endovascular graft |
| JP2002502626A (en) * | 1998-02-10 | 2002-01-29 | アーテミス・メディカル・インコーポレイテッド | Supplementary device and method of using the same |
| US6602265B2 (en) | 1998-02-10 | 2003-08-05 | Artemis Medical, Inc. | Tissue separation medical device and method |
| EP1054635B1 (en) * | 1998-02-10 | 2010-01-06 | Artemis Medical, Inc. | Occlusion, anchoring, tensioning or flow direction apparatus |
| US6651670B2 (en) * | 1998-02-13 | 2003-11-25 | Ventrica, Inc. | Delivering a conduit into a heart wall to place a coronary vessel in communication with a heart chamber and removing tissue from the vessel or heart wall to facilitate such communication |
| US20020144696A1 (en) * | 1998-02-13 | 2002-10-10 | A. Adam Sharkawy | Conduits for use in placing a target vessel in fluid communication with a source of blood |
| US7027398B2 (en) * | 2001-04-12 | 2006-04-11 | General Instrument Corporation | Method and apparatus for monitoring voice conversations from customer premises equipment |
| CA2320956A1 (en) * | 1998-02-13 | 1999-08-19 | Ventrica, Inc. | Methods and devices providing transmyocardial blood flow to the arterial vascular system of the heart |
| US6808498B2 (en) | 1998-02-13 | 2004-10-26 | Ventrica, Inc. | Placing a guide member into a heart chamber through a coronary vessel and delivering devices for placing the coronary vessel in communication with the heart chamber |
| US6193829B1 (en) | 1998-02-18 | 2001-02-27 | International Business Machines Corporation | Method and tooling for forming a stent |
| US6077296A (en) * | 1998-03-04 | 2000-06-20 | Endologix, Inc. | Endoluminal vascular prosthesis |
| US5938697A (en) * | 1998-03-04 | 1999-08-17 | Scimed Life Systems, Inc. | Stent having variable properties |
| US6129756A (en) | 1998-03-16 | 2000-10-10 | Teramed, Inc. | Biluminal endovascular graft system |
| US7208010B2 (en) | 2000-10-16 | 2007-04-24 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
| US7500988B1 (en) * | 2000-11-16 | 2009-03-10 | Cordis Corporation | Stent for use in a stent graft |
| US20040254635A1 (en) | 1998-03-30 | 2004-12-16 | Shanley John F. | Expandable medical device for delivery of beneficial agent |
| EP1222941B2 (en) † | 1998-03-30 | 2009-04-22 | Conor Medsystems, Inc. | Flexible medical device |
| US6241762B1 (en) * | 1998-03-30 | 2001-06-05 | Conor Medsystems, Inc. | Expandable medical device with ductile hinges |
| US7208011B2 (en) * | 2001-08-20 | 2007-04-24 | Conor Medsystems, Inc. | Implantable medical device with drug filled holes |
| US6264687B1 (en) * | 1998-04-20 | 2001-07-24 | Cordis Corporation | Multi-laminate stent having superelastic articulated sections |
| JP4583597B2 (en) | 1998-05-05 | 2010-11-17 | ボストン サイエンティフィック リミテッド | Smooth end stent |
| US6099559A (en) * | 1998-05-28 | 2000-08-08 | Medtronic Ave, Inc. | Endoluminal support assembly with capped ends |
| US6168621B1 (en) * | 1998-05-29 | 2001-01-02 | Scimed Life Systems, Inc. | Balloon expandable stent with a self-expanding portion |
| US6740113B2 (en) * | 1998-05-29 | 2004-05-25 | Scimed Life Systems, Inc. | Balloon expandable stent with a self-expanding portion |
| US6224627B1 (en) | 1998-06-15 | 2001-05-01 | Gore Enterprise Holdings, Inc. | Remotely removable covering and support |
| WO1999065419A1 (en) * | 1998-06-19 | 1999-12-23 | Endologix, Inc. | Self expanding bifurcated endovascular prosthesis |
| US6461380B1 (en) | 1998-07-28 | 2002-10-08 | Advanced Cardiovascular Systems, Inc. | Stent configuration |
| US6179860B1 (en) | 1998-08-19 | 2001-01-30 | Artemis Medical, Inc. | Target tissue localization device and method |
| US6273909B1 (en) | 1998-10-05 | 2001-08-14 | Teramed Inc. | Endovascular graft system |
| US6293967B1 (en) | 1998-10-29 | 2001-09-25 | Conor Medsystems, Inc. | Expandable medical device with ductile hinges |
| US6083259A (en) * | 1998-11-16 | 2000-07-04 | Frantzen; John J. | Axially non-contracting flexible radially expandable stent |
| US20060122691A1 (en) | 1998-12-03 | 2006-06-08 | Jacob Richter | Hybrid stent |
| US20060178727A1 (en) * | 1998-12-03 | 2006-08-10 | Jacob Richter | Hybrid amorphous metal alloy stent |
| US20070219642A1 (en) | 1998-12-03 | 2007-09-20 | Jacob Richter | Hybrid stent having a fiber or wire backbone |
| US6355059B1 (en) | 1998-12-03 | 2002-03-12 | Medinol, Ltd. | Serpentine coiled ladder stent |
| US6503270B1 (en) | 1998-12-03 | 2003-01-07 | Medinol Ltd. | Serpentine coiled ladder stent |
| US8382821B2 (en) | 1998-12-03 | 2013-02-26 | Medinol Ltd. | Helical hybrid stent |
| US6514063B2 (en) | 1999-01-07 | 2003-02-04 | International Business Machines Corporation | Tooling for forming a stent |
| US7655030B2 (en) | 2003-07-18 | 2010-02-02 | Boston Scientific Scimed, Inc. | Catheter balloon systems and methods |
| US6187034B1 (en) | 1999-01-13 | 2001-02-13 | John J. Frantzen | Segmented stent for flexible stent delivery system |
| US20050060027A1 (en) * | 1999-01-13 | 2005-03-17 | Advanced Stent Technologies, Inc. | Catheter balloon systems and methods |
| US6022359A (en) * | 1999-01-13 | 2000-02-08 | Frantzen; John J. | Stent delivery system featuring a flexible balloon |
| US7578828B2 (en) * | 1999-01-15 | 2009-08-25 | Medtronic, Inc. | Methods and devices for placing a conduit in fluid communication with a target vessel |
| US7025773B2 (en) | 1999-01-15 | 2006-04-11 | Medtronic, Inc. | Methods and devices for placing a conduit in fluid communication with a target vessel |
| US6398803B1 (en) | 1999-02-02 | 2002-06-04 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Partial encapsulation of stents |
| US6171327B1 (en) * | 1999-02-24 | 2001-01-09 | Scimed Life Systems, Inc. | Intravascular filter and method |
| US6210318B1 (en) | 1999-03-09 | 2001-04-03 | Abiomed, Inc. | Stented balloon pump system and method for using same |
| US6273910B1 (en) | 1999-03-11 | 2001-08-14 | Advanced Cardiovascular Systems, Inc. | Stent with varying strut geometry |
| US6730116B1 (en) | 1999-04-16 | 2004-05-04 | Medtronic, Inc. | Medical device for intraluminal endovascular stenting |
| US6273911B1 (en) | 1999-04-22 | 2001-08-14 | Advanced Cardiovascular Systems, Inc. | Variable strength stent |
| US20040044392A1 (en) * | 1999-05-03 | 2004-03-04 | Jomed Gmbh | Stent catheter system |
| US6290673B1 (en) | 1999-05-20 | 2001-09-18 | Conor Medsystems, Inc. | Expandable medical device delivery system and method |
| US7387639B2 (en) * | 1999-06-04 | 2008-06-17 | Advanced Stent Technologies, Inc. | Short sleeve stent delivery catheter and methods |
| US6884258B2 (en) | 1999-06-04 | 2005-04-26 | Advanced Stent Technologies, Inc. | Bifurcation lesion stent delivery using multiple guidewires |
| SE514718C2 (en) * | 1999-06-29 | 2001-04-09 | Jan Otto Solem | Apparatus for treating defective closure of the mitral valve apparatus |
| US6997951B2 (en) * | 1999-06-30 | 2006-02-14 | Edwards Lifesciences Ag | Method and device for treatment of mitral insufficiency |
| US7192442B2 (en) | 1999-06-30 | 2007-03-20 | Edwards Lifesciences Ag | Method and device for treatment of mitral insufficiency |
| US6409754B1 (en) * | 1999-07-02 | 2002-06-25 | Scimed Life Systems, Inc. | Flexible segmented stent |
| US20030150821A1 (en) * | 1999-07-16 | 2003-08-14 | Bates Mark C. | Emboli filtration system and methods of use |
| US6485507B1 (en) * | 1999-07-28 | 2002-11-26 | Scimed Life Systems | Multi-property nitinol by heat treatment |
| US6890350B1 (en) | 1999-07-28 | 2005-05-10 | Scimed Life Systems, Inc. | Combination self-expandable, balloon-expandable endoluminal device |
| US6589263B1 (en) | 1999-07-30 | 2003-07-08 | Incept Llc | Vascular device having one or more articulation regions and methods of use |
| US6616679B1 (en) | 1999-07-30 | 2003-09-09 | Incept, Llc | Rapid exchange vascular device for emboli and thrombus removal and methods of use |
| US6620182B1 (en) | 1999-07-30 | 2003-09-16 | Incept Llc | Vascular filter having articulation region and methods of use in the ascending aorta |
| US6530939B1 (en) | 1999-07-30 | 2003-03-11 | Incept, Llc | Vascular device having articulation region and methods of use |
| US20020022858A1 (en) * | 1999-07-30 | 2002-02-21 | Demond Jackson F. | Vascular device for emboli removal having suspension strut and methods of use |
| US6371970B1 (en) | 1999-07-30 | 2002-04-16 | Incept Llc | Vascular filter having articulation region and methods of use in the ascending aorta |
| US7320697B2 (en) * | 1999-07-30 | 2008-01-22 | Boston Scientific Scimed, Inc. | One piece loop and coil |
| US6544279B1 (en) * | 2000-08-09 | 2003-04-08 | Incept, Llc | Vascular device for emboli, thrombus and foreign body removal and methods of use |
| US6142987A (en) | 1999-08-03 | 2000-11-07 | Scimed Life Systems, Inc. | Guided filter with support wire and methods of use |
| US6235044B1 (en) * | 1999-08-04 | 2001-05-22 | Scimed Life Systems, Inc. | Percutaneous catheter and guidewire for filtering during ablation of mycardial or vascular tissue |
| US6168579B1 (en) | 1999-08-04 | 2001-01-02 | Scimed Life Systems, Inc. | Filter flush system and methods of use |
| US6540774B1 (en) | 1999-08-31 | 2003-04-01 | Advanced Cardiovascular Systems, Inc. | Stent design with end rings having enhanced strength and radiopacity |
| US20080018016A1 (en) * | 1999-09-10 | 2008-01-24 | Rapacki Alan R | Manufacturing conduits for use in placing a target vessel in fluid communication with a source of blood |
| US6635214B2 (en) * | 1999-09-10 | 2003-10-21 | Ventrica, Inc. | Manufacturing conduits for use in placing a target vessel in fluid communication with a source of blood |
| NZ517945A (en) * | 1999-09-23 | 2003-09-26 | Advanced Stent Tech Inc | Differentially expanding stent and methods of use |
| US6689156B1 (en) * | 1999-09-23 | 2004-02-10 | Advanced Stent Technologies, Inc. | Stent range transducers and methods of use |
| US6331189B1 (en) | 1999-10-18 | 2001-12-18 | Medtronic, Inc. | Flexible medical stent |
| US6325823B1 (en) * | 1999-10-29 | 2001-12-04 | Revasc Corporation | Endovascular prosthesis accommodating torsional and longitudinal displacements and methods of use |
| US7226475B2 (en) * | 1999-11-09 | 2007-06-05 | Boston Scientific Scimed, Inc. | Stent with variable properties |
| US6428569B1 (en) * | 1999-11-09 | 2002-08-06 | Scimed Life Systems Inc. | Micro structure stent configurations |
| US6371971B1 (en) | 1999-11-15 | 2002-04-16 | Scimed Life Systems, Inc. | Guidewire filter and methods of use |
| US6585758B1 (en) * | 1999-11-16 | 2003-07-01 | Scimed Life Systems, Inc. | Multi-section filamentary endoluminal stent |
| US6610087B1 (en) * | 1999-11-16 | 2003-08-26 | Scimed Life Systems, Inc. | Endoluminal stent having a matched stiffness region and/or a stiffness gradient and methods for providing stent kink resistance |
| US6280466B1 (en) * | 1999-12-03 | 2001-08-28 | Teramed Inc. | Endovascular graft system |
| US6471721B1 (en) | 1999-12-30 | 2002-10-29 | Advanced Cardiovascular Systems, Inc. | Vascular stent having increased radiopacity and method for making same |
| US6355058B1 (en) | 1999-12-30 | 2002-03-12 | Advanced Cardiovascular Systems, Inc. | Stent with radiopaque coating consisting of particles in a binder |
| US6537311B1 (en) | 1999-12-30 | 2003-03-25 | Advanced Cardiovascular Systems, Inc. | Stent designs for use in peripheral vessels |
| US6989028B2 (en) * | 2000-01-31 | 2006-01-24 | Edwards Lifesciences Ag | Medical system and method for remodeling an extravascular tissue structure |
| US7507252B2 (en) * | 2000-01-31 | 2009-03-24 | Edwards Lifesciences Ag | Adjustable transluminal annuloplasty system |
| US6402781B1 (en) * | 2000-01-31 | 2002-06-11 | Mitralife | Percutaneous mitral annuloplasty and cardiac reinforcement |
| DE60118657T2 (en) * | 2000-02-07 | 2007-04-05 | S & G Biotech Inc. | BLOOD TISSUE PLANT AND TRANSPLANT INTRODUCER |
| US6468301B1 (en) * | 2000-03-27 | 2002-10-22 | Aga Medical Corporation | Repositionable and recapturable vascular stent/graft |
| US6436132B1 (en) | 2000-03-30 | 2002-08-20 | Advanced Cardiovascular Systems, Inc. | Composite intraluminal prostheses |
| DE10026871A1 (en) | 2000-05-31 | 2002-02-28 | Caremed Medical Produkte Ag | stent |
| US7632303B1 (en) | 2000-06-07 | 2009-12-15 | Advanced Cardiovascular Systems, Inc. | Variable stiffness medical devices |
| US6652576B1 (en) | 2000-06-07 | 2003-11-25 | Advanced Cardiovascular Systems, Inc. | Variable stiffness stent |
| US6652579B1 (en) | 2000-06-22 | 2003-11-25 | Advanced Cardiovascular Systems, Inc. | Radiopaque stent |
| US6799637B2 (en) | 2000-10-20 | 2004-10-05 | Schlumberger Technology Corporation | Expandable tubing and method |
| US20020116049A1 (en) * | 2000-09-22 | 2002-08-22 | Scimed Life Systems, Inc. | Stent |
| US7766956B2 (en) * | 2000-09-22 | 2010-08-03 | Boston Scientific Scimed, Inc. | Intravascular stent and assembly |
| US8070792B2 (en) | 2000-09-22 | 2011-12-06 | Boston Scientific Scimed, Inc. | Stent |
| US6695833B1 (en) | 2000-09-27 | 2004-02-24 | Nellix, Inc. | Vascular stent-graft apparatus and forming method |
| US6616681B2 (en) * | 2000-10-05 | 2003-09-09 | Scimed Life Systems, Inc. | Filter delivery and retrieval device |
| AU9463401A (en) | 2000-10-16 | 2002-04-29 | Conor Medsystems Inc | Expandable medical device for delivery of beneficial agent |
| US6764507B2 (en) | 2000-10-16 | 2004-07-20 | Conor Medsystems, Inc. | Expandable medical device with improved spatial distribution |
| US7229472B2 (en) * | 2000-11-16 | 2007-06-12 | Cordis Corporation | Thoracic aneurysm repair prosthesis and system |
| US6942692B2 (en) * | 2000-11-16 | 2005-09-13 | Cordis Corporation | Supra-renal prosthesis and renal artery bypass |
| EP1212986A1 (en) * | 2000-12-08 | 2002-06-12 | SORIN BIOMEDICA CARDIO S.p.A. | An angioplasty stent and manufacturing method thereof |
| US6565599B1 (en) * | 2000-12-28 | 2003-05-20 | Advanced Cardiovascular Systems, Inc. | Hybrid stent |
| US20010044650A1 (en) * | 2001-01-12 | 2001-11-22 | Simso Eric J. | Stent for in-stent restenosis |
| NO335594B1 (en) * | 2001-01-16 | 2015-01-12 | Halliburton Energy Serv Inc | Expandable devices and methods thereof |
| US6663651B2 (en) | 2001-01-16 | 2003-12-16 | Incept Llc | Systems and methods for vascular filter retrieval |
| US6689151B2 (en) * | 2001-01-25 | 2004-02-10 | Scimed Life Systems, Inc. | Variable wall thickness for delivery sheath housing |
| US7510576B2 (en) * | 2001-01-30 | 2009-03-31 | Edwards Lifesciences Ag | Transluminal mitral annuloplasty |
| US20040073294A1 (en) * | 2002-09-20 | 2004-04-15 | Conor Medsystems, Inc. | Method and apparatus for loading a beneficial agent into an expandable medical device |
| US6790231B2 (en) * | 2001-02-05 | 2004-09-14 | Viacor, Inc. | Apparatus and method for reducing mitral regurgitation |
| US6964680B2 (en) * | 2001-02-05 | 2005-11-15 | Conor Medsystems, Inc. | Expandable medical device with tapered hinge |
| JP4184794B2 (en) * | 2001-02-05 | 2008-11-19 | ビアカー・インコーポレーテッド | Method and apparatus for improving mitral valve function |
| US6840950B2 (en) | 2001-02-20 | 2005-01-11 | Scimed Life Systems, Inc. | Low profile emboli capture device |
| US20020123786A1 (en) * | 2001-03-02 | 2002-09-05 | Ventrica, Inc. | Methods and devices for bypassing an obstructed target vessel by placing the vessel in communication with a heart chamber containing blood |
| CA2668308A1 (en) * | 2001-03-05 | 2002-12-05 | Viacor, Incorporated | Apparatus and method for reducing mitral regurgitation |
| US6537295B2 (en) * | 2001-03-06 | 2003-03-25 | Scimed Life Systems, Inc. | Wire and lock mechanism |
| US6890353B2 (en) * | 2001-03-23 | 2005-05-10 | Viacor, Inc. | Method and apparatus for reducing mitral regurgitation |
| US7186264B2 (en) * | 2001-03-29 | 2007-03-06 | Viacor, Inc. | Method and apparatus for improving mitral valve function |
| US7717708B2 (en) * | 2001-04-13 | 2010-05-18 | Orametrix, Inc. | Method and system for integrated orthodontic treatment planning using unified workstation |
| DE60234020D1 (en) * | 2001-04-16 | 2009-11-26 | Gary A Strobel | NEW ENDOPHYTIC MUSHROOMS AND ITS USE |
| DE10118944B4 (en) * | 2001-04-18 | 2013-01-31 | Merit Medical Systems, Inc. | Removable, essentially cylindrical implants |
| US20050021123A1 (en) | 2001-04-30 | 2005-01-27 | Jurgen Dorn | Variable speed self-expanding stent delivery system and luer locking connector |
| US8617231B2 (en) * | 2001-05-18 | 2013-12-31 | Boston Scientific Scimed, Inc. | Dual guidewire exchange catheter system |
| US6927359B2 (en) | 2001-06-14 | 2005-08-09 | Advanced Cardiovascular Systems, Inc. | Pulsed fiber laser cutting system for medical implants |
| US6521865B1 (en) | 2001-06-14 | 2003-02-18 | Advanced Cardiovascular Systems, Inc. | Pulsed fiber laser cutting system for medical implants |
| US7520892B1 (en) * | 2001-06-28 | 2009-04-21 | Advanced Cardiovascular Systems, Inc. | Low profile stent with flexible link |
| US6607554B2 (en) | 2001-06-29 | 2003-08-19 | Advanced Cardiovascular Systems, Inc. | Universal stent link design |
| US6605110B2 (en) | 2001-06-29 | 2003-08-12 | Advanced Cardiovascular Systems, Inc. | Stent with enhanced bendability and flexibility |
| US6997939B2 (en) | 2001-07-02 | 2006-02-14 | Rubicon Medical, Inc. | Methods, systems, and devices for deploying an embolic protection filter |
| US6962598B2 (en) * | 2001-07-02 | 2005-11-08 | Rubicon Medical, Inc. | Methods, systems, and devices for providing embolic protection |
| US6951570B2 (en) * | 2001-07-02 | 2005-10-04 | Rubicon Medical, Inc. | Methods, systems, and devices for deploying a filter from a filter device |
| IL144213A0 (en) * | 2001-07-09 | 2002-05-23 | Mind Guard Ltd | Implantable filter |
| US6786919B1 (en) * | 2001-07-10 | 2004-09-07 | Endovascular Technologies, Inc. | Self-expanding intravascular device with protector members |
| US20030023263A1 (en) * | 2001-07-24 | 2003-01-30 | Incept Llc | Apparatus and methods for aspirating emboli |
| US7547321B2 (en) * | 2001-07-26 | 2009-06-16 | Alveolus Inc. | Removable stent and method of using the same |
| US20030023261A1 (en) * | 2001-07-30 | 2003-01-30 | Scimed Life Systems Inc. | Chronic total occlusion device with variable stiffness shaft |
| US20030078654A1 (en) * | 2001-08-14 | 2003-04-24 | Taylor Daniel C. | Method and apparatus for improving mitral valve function |
| US7056338B2 (en) | 2003-03-28 | 2006-06-06 | Conor Medsystems, Inc. | Therapeutic agent delivery device with controlled therapeutic agent release rates |
| US6796999B2 (en) | 2001-09-06 | 2004-09-28 | Medinol Ltd. | Self articulating stent |
| US6878151B2 (en) * | 2001-09-27 | 2005-04-12 | Scimed Life Systems, Inc. | Medical retrieval device |
| US8262689B2 (en) * | 2001-09-28 | 2012-09-11 | Advanced Cardiovascular Systems, Inc. | Embolic filtering devices |
| US6755847B2 (en) | 2001-10-05 | 2004-06-29 | Scimed Life Systems, Inc. | Emboli capturing device and method of manufacture therefor |
| US20030069597A1 (en) * | 2001-10-10 | 2003-04-10 | Scimed Life Systems, Inc. | Loading tool |
| US20030078614A1 (en) * | 2001-10-18 | 2003-04-24 | Amr Salahieh | Vascular embolic filter devices and methods of use therefor |
| US7052500B2 (en) | 2001-10-19 | 2006-05-30 | Scimed Life Systems, Inc. | Embolus extractor |
| US7749243B2 (en) * | 2001-10-19 | 2010-07-06 | Boston Scientific Scimed, Inc. | Embolus extractor |
| DE60223886T2 (en) * | 2001-10-22 | 2008-11-06 | Terumo K.K. | STENT AND METHOD FOR THE PRODUCTION THEREOF |
| US7052487B2 (en) * | 2001-10-26 | 2006-05-30 | Cohn William E | Method and apparatus for reducing mitral regurgitation |
| US20030083692A1 (en) * | 2001-10-29 | 2003-05-01 | Scimed Life Systems, Inc. | Distal protection device and method of use thereof |
| JP4350515B2 (en) | 2001-11-09 | 2009-10-21 | ルビコン・メデイカル・インコーポレイテツド | Stent delivery device |
| US7594926B2 (en) * | 2001-11-09 | 2009-09-29 | Boston Scientific Scimed, Inc. | Methods, systems and devices for delivering stents |
| US6712843B2 (en) * | 2001-11-20 | 2004-03-30 | Scimed Life Systems, Inc | Stent with differential lengthening/shortening members |
| US6945994B2 (en) * | 2001-12-05 | 2005-09-20 | Boston Scientific Scimed, Inc. | Combined balloon-expanding and self-expanding stent |
| ATE462378T1 (en) * | 2001-12-28 | 2010-04-15 | Edwards Lifesciences Ag | DELAYED MEMORY DEVICE |
| SE524709C2 (en) * | 2002-01-11 | 2004-09-21 | Edwards Lifesciences Ag | Device for delayed reshaping of a heart vessel and a heart valve |
| US20030135265A1 (en) * | 2002-01-04 | 2003-07-17 | Stinson Jonathan S. | Prostheses implantable in enteral vessels |
| US6964681B2 (en) * | 2002-01-29 | 2005-11-15 | Medtronic Vascular, Inc. | Flared stent and method of use |
| US7125420B2 (en) * | 2002-02-05 | 2006-10-24 | Viacor, Inc. | Method and apparatus for improving mitral valve function |
| US8506647B2 (en) * | 2002-02-14 | 2013-08-13 | Boston Scientific Scimed, Inc. | System for maintaining body canal patency |
| US20030187498A1 (en) * | 2002-03-28 | 2003-10-02 | Medtronic Ave, Inc. | Chamfered stent strut and method of making same |
| US7052511B2 (en) * | 2002-04-04 | 2006-05-30 | Scimed Life Systems, Inc. | Delivery system and method for deployment of foreshortening endoluminal devices |
| US20030195609A1 (en) * | 2002-04-10 | 2003-10-16 | Scimed Life Systems, Inc. | Hybrid stent |
| US20030220683A1 (en) * | 2002-05-22 | 2003-11-27 | Zarouhi Minasian | Endoluminal device having barb assembly and method of using same |
| US6656220B1 (en) | 2002-06-17 | 2003-12-02 | Advanced Cardiovascular Systems, Inc. | Intravascular stent |
| US20050065596A1 (en) * | 2002-07-24 | 2005-03-24 | Xufan Tseng | Stents capable of controllably releasing histone deacetylase inhibitors |
| JP4418366B2 (en) | 2002-08-13 | 2010-02-17 | ウィルソン−クック・メディカル・インコーポレーテッド | ERCP catheter with removable handle for basket-compatible basket |
| GB0220340D0 (en) * | 2002-09-02 | 2002-10-09 | Anson Medical Ltd | Flexible stent-graft |
| EP2668933A1 (en) * | 2002-09-20 | 2013-12-04 | Innovational Holdings, LLC | Expandable medical device with openings for delivery of multiple beneficial agents |
| US20040127976A1 (en) * | 2002-09-20 | 2004-07-01 | Conor Medsystems, Inc. | Method and apparatus for loading a beneficial agent into an expandable medical device |
| US20040116997A1 (en) * | 2002-09-20 | 2004-06-17 | Taylor Charles S. | Stent-graft with positioning anchor |
| US8468678B2 (en) | 2002-10-02 | 2013-06-25 | Boston Scientific Scimed, Inc. | Expandable retrieval device |
| US7998163B2 (en) * | 2002-10-03 | 2011-08-16 | Boston Scientific Scimed, Inc. | Expandable retrieval device |
| US20040093056A1 (en) * | 2002-10-26 | 2004-05-13 | Johnson Lianw M. | Medical appliance delivery apparatus and method of use |
| US7875068B2 (en) | 2002-11-05 | 2011-01-25 | Merit Medical Systems, Inc. | Removable biliary stent |
| US7959671B2 (en) * | 2002-11-05 | 2011-06-14 | Merit Medical Systems, Inc. | Differential covering and coating methods |
| US7527644B2 (en) * | 2002-11-05 | 2009-05-05 | Alveolus Inc. | Stent with geometry determinated functionality and method of making the same |
| US7637942B2 (en) * | 2002-11-05 | 2009-12-29 | Merit Medical Systems, Inc. | Coated stent with geometry determinated functionality and method of making the same |
| US8282678B2 (en) * | 2002-11-13 | 2012-10-09 | Allium Medical Solutions Ltd. | Endoluminal lining |
| US20040098116A1 (en) | 2002-11-15 | 2004-05-20 | Callas Peter L. | Valve annulus constriction apparatus and method |
| US20050165469A1 (en) * | 2002-12-24 | 2005-07-28 | Michael Hogendijk | Vascular prosthesis including torsional stabilizer and methods of use |
| US7846198B2 (en) * | 2002-12-24 | 2010-12-07 | Novostent Corporation | Vascular prosthesis and methods of use |
| US7455687B2 (en) * | 2002-12-30 | 2008-11-25 | Advanced Cardiovascular Systems, Inc. | Polymer link hybrid stent |
| US7169177B2 (en) * | 2003-01-15 | 2007-01-30 | Boston Scientific Scimed, Inc. | Bifurcated stent |
| US20040138694A1 (en) * | 2003-01-15 | 2004-07-15 | Scimed Life Systems, Inc. | Intravascular filtering membrane and method of making an embolic protection filter device |
| EP2095835B1 (en) * | 2003-01-28 | 2013-04-03 | Gambro Lundia AB | Apparatus for monitoring a vascular access |
| US20040254600A1 (en) * | 2003-02-26 | 2004-12-16 | David Zarbatany | Methods and devices for endovascular mitral valve correction from the left coronary sinus |
| AU2004226327A1 (en) * | 2003-03-28 | 2004-10-14 | Innovational Holdings, Llc | Implantable medical device with beneficial agent concentration gradient |
| US7637934B2 (en) | 2003-03-31 | 2009-12-29 | Merit Medical Systems, Inc. | Medical appliance optical delivery and deployment apparatus and method |
| US20040199201A1 (en) * | 2003-04-02 | 2004-10-07 | Scimed Life Systems, Inc. | Embolectomy devices |
| US7972372B2 (en) * | 2003-04-14 | 2011-07-05 | Tryton Medical, Inc. | Kit for treating vascular bifurcations |
| US7758630B2 (en) * | 2003-04-14 | 2010-07-20 | Tryton Medical, Inc. | Helical ostium support for treating vascular bifurcations |
| US8083791B2 (en) * | 2003-04-14 | 2011-12-27 | Tryton Medical, Inc. | Method of treating a lumenal bifurcation |
| US7717953B2 (en) * | 2004-10-13 | 2010-05-18 | Tryton Medical, Inc. | Delivery system for placement of prosthesis at luminal OS |
| US7481834B2 (en) * | 2003-04-14 | 2009-01-27 | Tryton Medical, Inc. | Stent for placement at luminal os |
| US8109987B2 (en) * | 2003-04-14 | 2012-02-07 | Tryton Medical, Inc. | Method of treating a lumenal bifurcation |
| US7731747B2 (en) * | 2003-04-14 | 2010-06-08 | Tryton Medical, Inc. | Vascular bifurcation prosthesis with multiple thin fronds |
| US20040220612A1 (en) * | 2003-04-30 | 2004-11-04 | Swainston Kyle W | Slidable capture catheter |
| US7780611B2 (en) | 2003-05-01 | 2010-08-24 | Boston Scientific Scimed, Inc. | Medical instrument with controlled torque transmission |
| US7604660B2 (en) * | 2003-05-01 | 2009-10-20 | Merit Medical Systems, Inc. | Bifurcated medical appliance delivery apparatus and method |
| ES2364555T3 (en) | 2003-05-23 | 2011-09-06 | Boston Scientific Limited | CANNULAS WITH INCORPORATED LOOP TERMINATIONS. |
| US20060136053A1 (en) * | 2003-05-27 | 2006-06-22 | Rourke Jonathan M | Method and apparatus for improving mitral valve function |
| US7169179B2 (en) * | 2003-06-05 | 2007-01-30 | Conor Medsystems, Inc. | Drug delivery device and method for bi-directional drug delivery |
| US9039755B2 (en) | 2003-06-27 | 2015-05-26 | Medinol Ltd. | Helical hybrid stent |
| US9155639B2 (en) * | 2009-04-22 | 2015-10-13 | Medinol Ltd. | Helical hybrid stent |
| EP1646332B1 (en) | 2003-07-18 | 2015-06-17 | Edwards Lifesciences AG | Remotely activated mitral annuloplasty system |
| CA2533556A1 (en) * | 2003-07-23 | 2005-02-03 | Viacor, Inc. | Method and apparatus for improving mitral valve function |
| US7628806B2 (en) * | 2003-08-20 | 2009-12-08 | Boston Scientific Scimed, Inc. | Stent with improved resistance to migration |
| US8298280B2 (en) * | 2003-08-21 | 2012-10-30 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
| US8535344B2 (en) * | 2003-09-12 | 2013-09-17 | Rubicon Medical, Inc. | Methods, systems, and devices for providing embolic protection and removing embolic material |
| US7785653B2 (en) * | 2003-09-22 | 2010-08-31 | Innovational Holdings Llc | Method and apparatus for loading a beneficial agent into an expandable medical device |
| WO2005034807A1 (en) * | 2003-10-10 | 2005-04-21 | William A. Cook Australia Pty. Ltd | Composite stent graft |
| US7004176B2 (en) * | 2003-10-17 | 2006-02-28 | Edwards Lifesciences Ag | Heart valve leaflet locator |
| US7344557B2 (en) * | 2003-11-12 | 2008-03-18 | Advanced Stent Technologies, Inc. | Catheter balloon systems and methods |
| US7651514B2 (en) * | 2003-12-11 | 2010-01-26 | Boston Scientific Scimed, Inc. | Nose rider improvement for filter exchange and methods of use |
| US20050177228A1 (en) * | 2003-12-16 | 2005-08-11 | Solem Jan O. | Device for changing the shape of the mitral annulus |
| US7258697B1 (en) | 2003-12-22 | 2007-08-21 | Advanced Cardiovascular Systems, Inc. | Stent with anchors to prevent vulnerable plaque rupture during deployment |
| US20050159772A1 (en) * | 2004-01-20 | 2005-07-21 | Scimed Life Systems, Inc. | Sheath for use with an embolic protection filtering device |
| US20050159773A1 (en) * | 2004-01-20 | 2005-07-21 | Scimed Life Systems, Inc. | Expandable retrieval device with dilator tip |
| US20050209669A1 (en) * | 2004-03-03 | 2005-09-22 | Kao John A | System for stent placement in a vasculature bifurcation |
| US7473265B2 (en) | 2004-03-15 | 2009-01-06 | Boston Scientific Scimed, Inc. | Filter media and methods of manufacture |
| US7993397B2 (en) * | 2004-04-05 | 2011-08-09 | Edwards Lifesciences Ag | Remotely adjustable coronary sinus implant |
| EP1737391A2 (en) * | 2004-04-13 | 2007-01-03 | Cook Incorporated | Implantable frame with variable compliance |
| US20050240215A1 (en) * | 2004-04-21 | 2005-10-27 | Scimed Life Systems, Inc. | Magnetic embolic protection device and method |
| US20060004438A1 (en) * | 2004-04-30 | 2006-01-05 | Novostent Corporation | Prosthesis, delivery system and method for neurovascular aneurysm repair |
| US8241315B2 (en) | 2004-06-24 | 2012-08-14 | Boston Scientific Scimed, Inc. | Apparatus and method for treating occluded vasculature |
| US20060293612A1 (en) * | 2004-06-24 | 2006-12-28 | Boston Scientific Scimed, Inc. | Apparatus and method for treating occluded vasculature |
| AU2005260732B2 (en) * | 2004-06-30 | 2011-08-25 | Cardinal Health 529, Llc | Intraluminal medical device having asymetrical members |
| US7744641B2 (en) * | 2004-07-21 | 2010-06-29 | Boston Scientific Scimed, Inc. | Expandable framework with overlapping connectors |
| US8048145B2 (en) | 2004-07-22 | 2011-11-01 | Endologix, Inc. | Graft systems having filling structures supported by scaffolds and methods for their use |
| US7794472B2 (en) * | 2004-08-11 | 2010-09-14 | Boston Scientific Scimed, Inc. | Single wire intravascular filter |
| US20060064064A1 (en) * | 2004-09-17 | 2006-03-23 | Jang G D | Two-step/dual-diameter balloon angioplasty catheter for bifurcation and side-branch vascular anatomy |
| US7695506B2 (en) * | 2004-09-21 | 2010-04-13 | Boston Scientific Scimed, Inc. | Atraumatic connections for multi-component stents |
| US7887579B2 (en) * | 2004-09-29 | 2011-02-15 | Merit Medical Systems, Inc. | Active stent |
| US7344560B2 (en) * | 2004-10-08 | 2008-03-18 | Boston Scientific Scimed, Inc. | Medical devices and methods of making the same |
| US7621904B2 (en) | 2004-10-21 | 2009-11-24 | Boston Scientific Scimed, Inc. | Catheter with a pre-shaped distal tip |
| US20060095067A1 (en) * | 2004-11-01 | 2006-05-04 | Horng-Ban Lin | Lubricious filter |
| US8038696B2 (en) * | 2004-12-06 | 2011-10-18 | Boston Scientific Scimed, Inc. | Sheath for use with an embolic protection filter |
| AU2005314565B2 (en) | 2004-12-08 | 2012-02-02 | Innovational Holdings, Llc | Expandable medical device with differential hinge performance |
| US7211110B2 (en) * | 2004-12-09 | 2007-05-01 | Edwards Lifesciences Corporation | Diagnostic kit to assist with heart valve annulus adjustment |
| US7478465B1 (en) | 2005-01-10 | 2009-01-20 | Boston Scientific Scimed, Inc. | Method of securing a restraining member on a medical device |
| US7204464B2 (en) * | 2005-01-21 | 2007-04-17 | Boston Scientific Scimed, Inc. | Medical wire holder |
| US8480629B2 (en) * | 2005-01-28 | 2013-07-09 | Boston Scientific Scimed, Inc. | Universal utility board for use with medical devices and methods of use |
| US20080188803A1 (en) * | 2005-02-03 | 2008-08-07 | Jang G David | Triple-profile balloon catheter |
| JP5523700B2 (en) * | 2005-04-04 | 2014-06-18 | フレキシブル ステンティング ソリューションズ，インク． | Flexible stent |
| US20060276882A1 (en) * | 2005-04-11 | 2006-12-07 | Cook Incorporated | Medical device including remodelable material attached to frame |
| US7763198B2 (en) | 2005-04-12 | 2010-07-27 | Abbott Cardiovascular Systems Inc. | Method for retaining a vascular stent on a catheter |
| US7947207B2 (en) | 2005-04-12 | 2011-05-24 | Abbott Cardiovascular Systems Inc. | Method for retaining a vascular stent on a catheter |
| US8628565B2 (en) | 2005-04-13 | 2014-01-14 | Abbott Cardiovascular Systems Inc. | Intravascular stent |
| US7731654B2 (en) * | 2005-05-13 | 2010-06-08 | Merit Medical Systems, Inc. | Delivery device with viewing window and associated method |
| US7500989B2 (en) * | 2005-06-03 | 2009-03-10 | Edwards Lifesciences Corp. | Devices and methods for percutaneous repair of the mitral valve via the coronary sinus |
| AU2006269419A1 (en) * | 2005-07-07 | 2007-01-18 | Nellix, Inc. | Systems and methods for endovascular aneurysm treatment |
| US20080221673A1 (en) * | 2005-08-12 | 2008-09-11 | Donald Bobo | Medical implant with reinforcement mechanism |
| WO2007021893A1 (en) * | 2005-08-12 | 2007-02-22 | Edwards Lifesciences Corporation | Medical implant with reinforcement mechanism |
| ATE526911T1 (en) | 2005-08-17 | 2011-10-15 | Bard Inc C R | VARIABLE SPEED STENT DELIVERY SYSTEM |
| GB0517085D0 (en) * | 2005-08-19 | 2005-09-28 | Angiomed Ag | Polymer prosthesis |
| US8043366B2 (en) * | 2005-09-08 | 2011-10-25 | Boston Scientific Scimed, Inc. | Overlapping stent |
| US20070073391A1 (en) * | 2005-09-28 | 2007-03-29 | Henry Bourang | System and method for delivering a mitral valve repair device |
| US20070173926A1 (en) * | 2005-12-09 | 2007-07-26 | Bobo Donald E Jr | Anchoring system for medical implant |
| US20070150041A1 (en) * | 2005-12-22 | 2007-06-28 | Nellix, Inc. | Methods and systems for aneurysm treatment using filling structures |
| CA2936205C (en) | 2006-01-13 | 2018-08-21 | C.R. Bard, Inc. | Stent delivery system |
| US11026822B2 (en) | 2006-01-13 | 2021-06-08 | C. R. Bard, Inc. | Stent delivery system |
| CN101378714A (en) * | 2006-02-01 | 2009-03-04 | 宝洁公司 | Absorbent article with urine-permeable coversheet |
| WO2007092735A2 (en) | 2006-02-02 | 2007-08-16 | Innovative Bio Therapies | An extracorporeal cell-based therapeutic device and delivery system |
| US7637946B2 (en) | 2006-02-09 | 2009-12-29 | Edwards Lifesciences Corporation | Coiled implant for mitral valve repair |
| US8821561B2 (en) * | 2006-02-22 | 2014-09-02 | Boston Scientific Scimed, Inc. | Marker arrangement for bifurcation catheter |
| US8828077B2 (en) | 2006-03-15 | 2014-09-09 | Medinol Ltd. | Flat process of preparing drug eluting stents |
| US7568753B2 (en) * | 2006-06-15 | 2009-08-04 | Mattel, Inc. | Children's ride-on vehicles with reconfigured bodies and methods for forming the same |
| US7651523B2 (en) * | 2006-07-24 | 2010-01-26 | Cook Incorporated | Intraluminal device with flexible regions |
| GB0615658D0 (en) | 2006-08-07 | 2006-09-13 | Angiomed Ag | Hand-held actuator device |
| US20080051879A1 (en) * | 2006-08-23 | 2008-02-28 | Cook Incorporated | Methods of treating venous valve related conditions with a flow-modifying implantable medical device |
| US20080065205A1 (en) * | 2006-09-11 | 2008-03-13 | Duy Nguyen | Retrievable implant and method for treatment of mitral regurgitation |
| US7988720B2 (en) | 2006-09-12 | 2011-08-02 | Boston Scientific Scimed, Inc. | Longitudinally flexible expandable stent |
| US20080071343A1 (en) * | 2006-09-15 | 2008-03-20 | Kevin John Mayberry | Multi-segmented graft deployment system |
| US7780798B2 (en) | 2006-10-13 | 2010-08-24 | Boston Scientific Scimed, Inc. | Medical devices including hardened alloys |
| US8388679B2 (en) | 2007-01-19 | 2013-03-05 | Maquet Cardiovascular Llc | Single continuous piece prosthetic tubular aortic conduit and method for manufacturing the same |
| US20080255447A1 (en) * | 2007-04-16 | 2008-10-16 | Henry Bourang | Diagnostic catheter |
| US9144509B2 (en) | 2007-05-31 | 2015-09-29 | Abbott Cardiovascular Systems Inc. | Method and apparatus for delivering an agent to a kidney |
| US9364586B2 (en) | 2007-05-31 | 2016-06-14 | Abbott Cardiovascular Systems Inc. | Method and apparatus for improving delivery of an agent to a kidney |
| US8216209B2 (en) | 2007-05-31 | 2012-07-10 | Abbott Cardiovascular Systems Inc. | Method and apparatus for delivering an agent to a kidney |
| US9149610B2 (en) | 2007-05-31 | 2015-10-06 | Abbott Cardiovascular Systems Inc. | Method and apparatus for improving delivery of an agent to a kidney |
| DE102007025921A1 (en) * | 2007-06-02 | 2008-12-04 | Biotronik Vi Patent Ag | Medical implant, in particular stent |
| GB0713497D0 (en) | 2007-07-11 | 2007-08-22 | Angiomed Ag | Device for catheter sheath retraction |
| US8486134B2 (en) | 2007-08-01 | 2013-07-16 | Boston Scientific Scimed, Inc. | Bifurcation treatment system and methods |
| US7988723B2 (en) | 2007-08-02 | 2011-08-02 | Flexible Stenting Solutions, Inc. | Flexible stent |
| US8100820B2 (en) * | 2007-08-22 | 2012-01-24 | Edwards Lifesciences Corporation | Implantable device for treatment of ventricular dilation |
| US20090082841A1 (en) * | 2007-09-26 | 2009-03-26 | Boston Scientific Corporation | Apparatus for securing stent barbs |
| US8663309B2 (en) * | 2007-09-26 | 2014-03-04 | Trivascular, Inc. | Asymmetric stent apparatus and method |
| US8226701B2 (en) | 2007-09-26 | 2012-07-24 | Trivascular, Inc. | Stent and delivery system for deployment thereof |
| US20090082845A1 (en) * | 2007-09-26 | 2009-03-26 | Boston Scientific Corporation | Alignment stent apparatus and method |
| US8066755B2 (en) * | 2007-09-26 | 2011-11-29 | Trivascular, Inc. | System and method of pivoted stent deployment |
| CN101917929A (en) | 2007-10-04 | 2010-12-15 | 特里瓦斯库拉尔公司 | Modular vascular graft for low profile percutaneous delivery |
| US8439859B2 (en) * | 2007-10-08 | 2013-05-14 | Ais Gmbh Aachen Innovative Solutions | Catheter device |
| WO2009055286A1 (en) * | 2007-10-24 | 2009-04-30 | Edwards Lifesciences Corporation | Percutaneous nitinol stent extraction device |
| US8936567B2 (en) * | 2007-11-14 | 2015-01-20 | Boston Scientific Scimed, Inc. | Balloon bifurcated lumen treatment |
| US8328861B2 (en) | 2007-11-16 | 2012-12-11 | Trivascular, Inc. | Delivery system and method for bifurcated graft |
| US8083789B2 (en) * | 2007-11-16 | 2011-12-27 | Trivascular, Inc. | Securement assembly and method for expandable endovascular device |
| US20100331958A1 (en) * | 2007-12-20 | 2010-12-30 | Trivascular, Inc. | Hinged endovascular device |
| WO2009088953A2 (en) * | 2007-12-31 | 2009-07-16 | Boston Scientific Scimed Inc. | Bifurcation stent delivery system and methods |
| US8196279B2 (en) * | 2008-02-27 | 2012-06-12 | C. R. Bard, Inc. | Stent-graft covering process |
| US8236040B2 (en) | 2008-04-11 | 2012-08-07 | Endologix, Inc. | Bifurcated graft deployment systems and methods |
| CA2721950A1 (en) | 2008-04-25 | 2009-10-29 | Nellix, Inc. | Stent graft delivery system |
| US8377108B2 (en) | 2008-06-02 | 2013-02-19 | Boston Scientific Scimed, Inc. | Staggered two balloon bifurcation catheter assembly and methods |
| AU2009256084A1 (en) * | 2008-06-04 | 2009-12-10 | Nellix, Inc. | Sealing apparatus and methods of use |
| JP5662310B2 (en) * | 2008-06-05 | 2015-01-28 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | Shrinkable branch device and method of manufacturing the same |
| WO2010071692A2 (en) * | 2008-06-18 | 2010-06-24 | Innovative Biotherapies, Inc. | Methods for enhanced propagation of cells |
| EP2293838B1 (en) | 2008-07-01 | 2012-08-08 | Endologix, Inc. | Catheter system |
| US9149376B2 (en) * | 2008-10-06 | 2015-10-06 | Cordis Corporation | Reconstrainable stent delivery system |
| US20100152711A1 (en) * | 2008-12-15 | 2010-06-17 | Boston Scientific Scimed, Inc. | Offset coupling region |
| US8444669B2 (en) | 2008-12-15 | 2013-05-21 | Boston Scientific Scimed, Inc. | Embolic filter delivery system and method |
| WO2010091106A1 (en) | 2009-02-03 | 2010-08-12 | Abbott Cardiovascular Systems Inc. | Improved laser cutting system |
| US8872062B2 (en) | 2009-02-03 | 2014-10-28 | Abbott Cardiovascular Systems Inc. | Laser cutting process for forming stents |
| WO2010091100A1 (en) | 2009-02-03 | 2010-08-12 | Abbott Cardiovascular Systems Inc. | Multiple beam laser system for forming stents |
| US20100228337A1 (en) * | 2009-03-04 | 2010-09-09 | Abbott Laboratories Vascular Enterprises Limited | Mirror image stent and method of use |
| JP2012524641A (en) * | 2009-04-24 | 2012-10-18 | フレキシブル ステンティング ソリューションズ，インク． | Flexible device |
| US8382818B2 (en) * | 2009-07-02 | 2013-02-26 | Tryton Medical, Inc. | Ostium support for treating vascular bifurcations |
| WO2011017123A2 (en) | 2009-07-27 | 2011-02-10 | Endologix, Inc. | Stent graft |
| CA2779080C (en) * | 2009-10-30 | 2018-01-16 | Cordis Corporation | Intraluminal device with improved flexibility and durability |
| WO2011082227A1 (en) * | 2009-12-29 | 2011-07-07 | Boston Scientific Scimed, Inc. | High strength low opening pressure stent design |
| US20110276078A1 (en) | 2009-12-30 | 2011-11-10 | Nellix, Inc. | Filling structure for a graft system and methods of use |
| CN102113921A (en) * | 2009-12-30 | 2011-07-06 | 微创医疗器械(上海)有限公司 | Intervention-type heart valve |
| WO2011100367A2 (en) * | 2010-02-10 | 2011-08-18 | Trivascular, Inc. | Fill tube manifold and delivery methods for endovascular graft |
| US20120046731A1 (en) * | 2010-04-14 | 2012-02-23 | Abbott Vascular | Intraluminal scaffold with conforming axial strut |
| CN101933855B (en) * | 2010-08-26 | 2013-06-12 | 先健科技(深圳)有限公司 | Recyclable vascular stent and recycling method thereof |
| US8556511B2 (en) | 2010-09-08 | 2013-10-15 | Abbott Cardiovascular Systems, Inc. | Fluid bearing to support stent tubing during laser cutting |
| GB201017834D0 (en) | 2010-10-21 | 2010-12-01 | Angiomed Ag | System to deliver a bodily implant |
| US9707108B2 (en) | 2010-11-24 | 2017-07-18 | Tryton Medical, Inc. | Support for treating vascular bifurcations |
| US8696741B2 (en) | 2010-12-23 | 2014-04-15 | Maquet Cardiovascular Llc | Woven prosthesis and method for manufacturing the same |
| JP2014508559A (en) | 2010-12-30 | 2014-04-10 | ボストン サイエンティフィック サイムド，インコーポレイテッド | Multi-stage open stent design |
| US8801768B2 (en) | 2011-01-21 | 2014-08-12 | Endologix, Inc. | Graft systems having semi-permeable filling structures and methods for their use |
| WO2012118901A1 (en) | 2011-03-01 | 2012-09-07 | Endologix, Inc. | Catheter system and methods of using same |
| US8790388B2 (en) | 2011-03-03 | 2014-07-29 | Boston Scientific Scimed, Inc. | Stent with reduced profile |
| WO2012118526A1 (en) | 2011-03-03 | 2012-09-07 | Boston Scientific Scimed, Inc. | Low strain high strength stent |
| US8821478B2 (en) | 2011-03-04 | 2014-09-02 | Boston Scientific Scimed, Inc. | Catheter with variable stiffness |
| JP5976777B2 (en) | 2011-04-06 | 2016-08-24 | エンドーロジックス インコーポレイテッド | Methods and systems for the treatment of intravascular aneurysms |
| JP5913910B2 (en) * | 2011-04-26 | 2016-04-27 | 国際計測器株式会社 | Linear motion actuator and vibration device |
| WO2012174389A1 (en) | 2011-06-15 | 2012-12-20 | Phraxis Inc. | Anastomotic connector and system for delivery |
| US10940167B2 (en) | 2012-02-10 | 2021-03-09 | Cvdevices, Llc | Methods and uses of biological tissues for various stent and other medical applications |
| US8992595B2 (en) | 2012-04-04 | 2015-03-31 | Trivascular, Inc. | Durable stent graft with tapered struts and stable delivery methods and devices |
| US9498363B2 (en) | 2012-04-06 | 2016-11-22 | Trivascular, Inc. | Delivery catheter for endovascular device |
| EP2841024B1 (en) | 2012-04-26 | 2017-05-03 | Tryton Medical, Inc. | Support for treating vascular bifurcations |
| WO2013187927A1 (en) | 2012-06-15 | 2013-12-19 | Phraxis Inc. | Arterial and venous anchor devices forming an anastomotic connector and system for delivery |
| US20140114266A1 (en) * | 2012-10-22 | 2014-04-24 | Ams Research Corporation | Ostomy Implant System and Method |
| US20140180380A1 (en) | 2012-12-20 | 2014-06-26 | Sanford Health | Stent Deployment Device and Methods for Use |
| AU2014214700B2 (en) | 2013-02-11 | 2018-01-18 | Cook Medical Technologies Llc | Expandable support frame and medical device |
| US9289536B2 (en) | 2013-03-14 | 2016-03-22 | Endologix, Inc. | Method for forming materials in situ within a medical device |
| CA2906372C (en) | 2013-03-14 | 2018-08-28 | Medinol Ltd. | Helical hybrid stent |
| CN106456347B (en) | 2014-03-18 | 2018-11-13 | 波士顿科学国际有限公司 | Reduce the support Design of granulation and inflammation |
| US9895243B2 (en) | 2014-07-17 | 2018-02-20 | W. L. Gore & Associates, Inc. | Stent having adjacent elements connected by narrow flexible webs |
| IL250181B2 (en) | 2014-07-20 | 2024-04-01 | Bruckheimer Elchanan | Pulmonary artery implant apparatus |
| JP2018524025A (en) | 2015-06-30 | 2018-08-30 | エンドロジックス、インク | Lock assembly for coupling guidewire to delivery system |
| EP3324884A1 (en) * | 2015-07-19 | 2018-05-30 | Sanford Health | Bridging stent graft with combination balloon expandable and self-expandable stents and methods for use |
| CN105147424A (en) * | 2015-09-25 | 2015-12-16 | 北京工业大学 | Novel vascular stent |
| US10130465B2 (en) | 2016-02-23 | 2018-11-20 | Abbott Cardiovascular Systems Inc. | Bifurcated tubular graft for treating tricuspid regurgitation |
| USD803088S1 (en) * | 2016-08-10 | 2017-11-21 | Antonio Mandreucci | Stent bracelet |
| US11771434B2 (en) | 2016-09-28 | 2023-10-03 | Restore Medical Ltd. | Artery medical apparatus and methods of use thereof |
| WO2018225059A1 (en) | 2017-06-05 | 2018-12-13 | Restore Medical Ltd | Double walled fixed length stent like apparatus and methods of use thereof |
| US10575973B2 (en) | 2018-04-11 | 2020-03-03 | Abbott Cardiovascular Systems Inc. | Intravascular stent having high fatigue performance |
| US11291570B2 (en) | 2018-04-27 | 2022-04-05 | Cook Medical Technologies Llc | Hybrid stent and delivery system |
| US11129702B2 (en) | 2018-05-09 | 2021-09-28 | Boston Scientific Scimed, Inc. | Pedal access embolic filtering sheath |
| US11471264B2 (en) * | 2020-04-01 | 2022-10-18 | Medtronic Vascular, Inc. | Branching stent graft with mechanical interlock |
| CN111789703B (en) * | 2020-08-07 | 2021-09-28 | 上海恩盛医疗科技有限公司 | Blood vessel stent construction method based on modularization |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6198254A (en) * | 1984-10-19 | 1986-05-16 | ザ・ベントリー―ハリス・マニュファクチュアリング・カンパニー | Prosthetic stent |
| IL79458A0 (en) * | 1985-07-19 | 1986-10-31 | Meadox Surgimed As | Dilatation catheter |
| US4733665C2 (en) * | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
| US5102417A (en) * | 1985-11-07 | 1992-04-07 | Expandable Grafts Partnership | Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft |
| US4740207A (en) * | 1986-09-10 | 1988-04-26 | Kreamer Jeffry W | Intralumenal graft |
| US4893623A (en) * | 1986-12-09 | 1990-01-16 | Advanced Surgical Intervention, Inc. | Method and apparatus for treating hypertrophy of the prostate gland |
| IT1225673B (en) * | 1988-07-22 | 1990-11-22 | Luigi Bozzo | DESTRUCTOR DEVICE FOR USE IN THE URINARY OBSTRUCTIVE PATHOLOGY OF THE MALE AND INSTRUCTOR-EXTRACTOR INSTRUMENT OF THE DEVICE ITSELF |
| CA2026604A1 (en) * | 1989-10-02 | 1991-04-03 | Rodney G. Wolff | Articulated stent |
| US5064435A (en) * | 1990-06-28 | 1991-11-12 | Schneider (Usa) Inc. | Self-expanding prosthesis having stable axial length |
-
1991
- 1991-11-08 FR FR9113820A patent/FR2683449A1/en not_active Withdrawn
-
1992
- 1992-11-05 DK DK92402991.1T patent/DK0541443T3/en active
- 1992-11-05 DE DE69208026T patent/DE69208026T2/en not_active Expired - Fee Related
- 1992-11-05 AT AT92402991T patent/ATE133554T1/en not_active IP Right Cessation
- 1992-11-05 ES ES92402991T patent/ES2085595T3/en not_active Expired - Lifetime
- 1992-11-05 EP EP92402991A patent/EP0541443B1/en not_active Expired - Lifetime
- 1992-11-06 CA CA2082367A patent/CA2082367C/en not_active Expired - Fee Related
- 1992-11-06 US US07/972,977 patent/US5383892A/en not_active Expired - Fee Related
Also Published As
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|---|---|
| EP0541443A1 (en) | 1993-05-12 |
| DE69208026T2 (en) | 1996-09-05 |
| US5383892A (en) | 1995-01-24 |
| CA2082367A1 (en) | 1993-05-09 |
| ES2085595T3 (en) | 1996-06-01 |
| FR2683449A1 (en) | 1993-05-14 |
| EP0541443B1 (en) | 1996-01-31 |
| ATE133554T1 (en) | 1996-02-15 |
| DE69208026D1 (en) | 1996-03-14 |
| DK0541443T3 (en) | 1996-06-03 |
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| EEER | Examination request | ||
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