CA2082960A1 - An apparatus for preparing a concentrate of coagulation factors, such as fibrinogen, from a blood sample - Google Patents

An apparatus for preparing a concentrate of coagulation factors, such as fibrinogen, from a blood sample

Info

Publication number
CA2082960A1
CA2082960A1 CA002082960A CA2082960A CA2082960A1 CA 2082960 A1 CA2082960 A1 CA 2082960A1 CA 002082960 A CA002082960 A CA 002082960A CA 2082960 A CA2082960 A CA 2082960A CA 2082960 A1 CA2082960 A1 CA 2082960A1
Authority
CA
Canada
Prior art keywords
chamber
concentrate
blood sample
plasma fraction
fibrinogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002082960A
Other languages
French (fr)
Other versions
CA2082960C (en
Inventor
Ulla Weis-Fogh
Soren Hern
Niels Erik Holm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VIVOLUTION AS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2082960A1 publication Critical patent/CA2082960A1/en
Application granted granted Critical
Publication of CA2082960C publication Critical patent/CA2082960C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/369—Temperature treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0445—Proteins
    • A61M2202/0447—Glycoproteins
    • A61M2202/0449—Fibrinogen, also called factor 1

Abstract

An apparatus for preparing a concentrate of coagulation factors, such as fibrinogen, from a blood sample, comprises a first chamber (14) for collection and separation of said blood sample so as to separate a plasma fraction, and a second chamber (15) for collection of said plasma fraction through a tubing member (22, 30) and a valve (24) and for precipitation of said concentrate. The ap-paratus comprises furthermore a removable syringe (36) for receiving the concentrate from the second chamber (15) through a tubing member (32). The first and the second chamber (14, 15) are partially defined by the same integrally formed solid con-tainer wall (2) and comprise a common partition.
The first chamber (14) is further defined by a pis-ton (4) displaceable both in connection with the blood sample collection and the transfer of said plasma fraction to the second chamber (15) and in connection with returning said plasma fraction to the first chamber (14) upon the precipitation of the concentrate.
CA002082960A 1990-05-14 1991-05-14 An apparatus for preparing a concentrate of coagulation factors, such as fibrinogen, from a blood sample Expired - Fee Related CA2082960C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK1194/90 1990-05-14
DK119490A DK119490D0 (en) 1990-05-14 1990-05-14 Apparatus for the preparation of a concentrate of coagulation factors, such as the fibrinogen, from a blood portion
PCT/DK1991/000131 WO1991017778A1 (en) 1990-05-14 1991-05-14 An apparatus for preparing a concentrate of coagulation factors, such as fibrinogen, from a blood sample

Publications (2)

Publication Number Publication Date
CA2082960A1 true CA2082960A1 (en) 1991-11-15
CA2082960C CA2082960C (en) 2002-07-02

Family

ID=8102033

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002082960A Expired - Fee Related CA2082960C (en) 1990-05-14 1991-05-14 An apparatus for preparing a concentrate of coagulation factors, such as fibrinogen, from a blood sample

Country Status (25)

Country Link
US (1) US5480378A (en)
EP (1) EP0528949B1 (en)
JP (1) JP2963539B2 (en)
KR (1) KR0156008B1 (en)
CN (1) CN1043737C (en)
AT (1) ATE134883T1 (en)
AU (1) AU645574B2 (en)
CA (1) CA2082960C (en)
CZ (1) CZ281425B6 (en)
DE (1) DE69117750T2 (en)
DK (2) DK119490D0 (en)
ES (1) ES2084164T3 (en)
FI (1) FI103869B1 (en)
GR (1) GR3019250T3 (en)
HU (1) HU214943B (en)
IE (1) IE73213B1 (en)
IL (1) IL98076A (en)
MX (1) MX170505B (en)
NO (1) NO177953B1 (en)
NZ (1) NZ238111A (en)
PT (1) PT97666B (en)
SK (1) SK279151B6 (en)
WO (1) WO1991017778A1 (en)
YU (1) YU84291A (en)
ZA (1) ZA913638B (en)

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Also Published As

Publication number Publication date
NO177953B1 (en) 1996-01-15
CN1056632A (en) 1991-12-04
JP2963539B2 (en) 1999-10-18
HU9203570D0 (en) 1993-03-29
EP0528949B1 (en) 1996-03-06
NZ238111A (en) 1994-04-27
SK279151B6 (en) 1998-07-08
AU645574B2 (en) 1994-01-20
CA2082960C (en) 2002-07-02
US5480378A (en) 1996-01-02
GR3019250T3 (en) 1996-06-30
ES2084164T3 (en) 1996-05-01
FI103869B (en) 1999-10-15
FI103869B1 (en) 1999-10-15
JPH05506379A (en) 1993-09-22
NO924392D0 (en) 1992-11-13
AU7902291A (en) 1991-12-10
IL98076A0 (en) 1992-06-21
HU214943B (en) 1998-08-28
DK119490D0 (en) 1990-05-14
FI925171A (en) 1992-11-13
IE73213B1 (en) 1997-05-07
YU84291A (en) 1994-06-10
KR0156008B1 (en) 1998-10-15
HUT67381A (en) 1995-04-28
IE911624A1 (en) 1991-11-20
ATE134883T1 (en) 1996-03-15
EP0528949A1 (en) 1993-03-03
IL98076A (en) 1994-05-30
NO177953B (en) 1995-09-18
DE69117750T2 (en) 1996-09-05
CS141691A3 (en) 1992-02-19
NO177953C (en) 1995-12-27
PT97666A (en) 1993-06-30
FI925171A0 (en) 1992-11-13
CZ281425B6 (en) 1996-09-11
PT97666B (en) 1998-09-30
MX170505B (en) 1993-08-26
NO924392A (en) 1992-11-13
WO1991017778A1 (en) 1991-11-28
ZA913638B (en) 1992-02-26
DK0528949T3 (en) 1996-07-22
CN1043737C (en) 1999-06-23
DE69117750D1 (en) 1996-04-11

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