CA2087957A1 - Tissue bonding and sealing composition and method of using the same - Google Patents

Tissue bonding and sealing composition and method of using the same

Info

Publication number
CA2087957A1
CA2087957A1 CA002087957A CA2087957A CA2087957A1 CA 2087957 A1 CA2087957 A1 CA 2087957A1 CA 002087957 A CA002087957 A CA 002087957A CA 2087957 A CA2087957 A CA 2087957A CA 2087957 A1 CA2087957 A1 CA 2087957A1
Authority
CA
Canada
Prior art keywords
same
sealing composition
tissue bonding
composition
bonding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002087957A
Other languages
French (fr)
Other versions
CA2087957C (en
Inventor
Lawrence Samuel Bass
Steven Kenneth Libutti
Alexander Mellon Eaton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University of New York
Original Assignee
Lawrence Samuel Bass
Steven Kenneth Libutti
Alexander Mellon Eaton
The Trustees Of Columbia University In The City Of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27072241&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2087957(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/560,069 external-priority patent/US5209776A/en
Application filed by Lawrence Samuel Bass, Steven Kenneth Libutti, Alexander Mellon Eaton, The Trustees Of Columbia University In The City Of New York filed Critical Lawrence Samuel Bass
Publication of CA2087957A1 publication Critical patent/CA2087957A1/en
Application granted granted Critical
Publication of CA2087957C publication Critical patent/CA2087957C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A61B2017/00495—Surgical glue applicators for two-component glue

Abstract

Disclosed is a composition for bonding separated tissues together or for coating tissues or prosthetic materials including at least one natural or synthetic peptide and at least one support material which may be activated by energy and to methods of making and using the same.
CA002087957A 1990-07-27 1991-07-23 Tissue bonding and sealing composition and method of using the same Expired - Lifetime CA2087957C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US07/560,069 US5209776A (en) 1990-07-27 1990-07-27 Tissue bonding and sealing composition and method of using the same
US560,069 1990-07-27
US727,607 1991-07-09
US07/727,607 US5292362A (en) 1990-07-27 1991-07-09 Tissue bonding and sealing composition and method of using the same
PCT/US1991/005186 WO1992002238A1 (en) 1990-07-27 1991-07-23 Tissue bonding and sealing composition and method of using the same

Publications (2)

Publication Number Publication Date
CA2087957A1 true CA2087957A1 (en) 1992-01-28
CA2087957C CA2087957C (en) 2004-07-20

Family

ID=27072241

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002087957A Expired - Lifetime CA2087957C (en) 1990-07-27 1991-07-23 Tissue bonding and sealing composition and method of using the same

Country Status (9)

Country Link
US (1) US5292362A (en)
EP (1) EP0542880B1 (en)
JP (1) JPH06507376A (en)
AT (1) ATE183656T1 (en)
AU (1) AU8497991A (en)
CA (1) CA2087957C (en)
DE (1) DE69131556T2 (en)
ES (1) ES2137930T3 (en)
WO (1) WO1992002238A1 (en)

Families Citing this family (269)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660692A (en) * 1988-02-24 1997-08-26 Cedars-Sinai Medical Center Method of crosslinking amino acid-containing polymers using photoactivatable chemical crosslinkers
US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5197973A (en) * 1990-12-14 1993-03-30 Creative Biomolecules, Inc. Synthetic bioadhesive
US5219895A (en) * 1991-01-29 1993-06-15 Autogenesis Technologies, Inc. Collagen-based adhesives and sealants and methods of preparation and use thereof
US5669934A (en) * 1991-02-13 1997-09-23 Fusion Medical Technologies, Inc. Methods for joining tissue by applying radiofrequency energy to performed collagen films and sheets
US5749895A (en) * 1991-02-13 1998-05-12 Fusion Medical Technologies, Inc. Method for bonding or fusion of biological tissue and material
CA2103727A1 (en) * 1991-02-13 1992-08-14 Philip N. Sawyer Filler material for use in tissue welding
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US6440427B1 (en) 1991-06-17 2002-08-27 Biovitrum Ab Tissue treatment composition comprising fibrin or fibrinogen and biodegradable and biocompatible polymer
SE9101853D0 (en) * 1991-06-17 1991-06-17 Jonas Wadstroem IMPROVED TISSUE ASHESIVE
US5758663A (en) * 1992-04-10 1998-06-02 Wilk; Peter J. Coronary artery by-pass method
GB9211432D0 (en) * 1992-05-29 1992-07-15 Jevco Ltd Absorbable bone sealant
US5716675A (en) 1992-11-25 1998-02-10 E. Khashoggi Industries Methods for treating the surface of starch-based articles with glycerin
US5552452A (en) * 1993-03-15 1996-09-03 Arch Development Corp. Organic tissue glue for closure of wounds
WO1994021324A1 (en) * 1993-03-23 1994-09-29 Focal, Inc. Apparatus and method for local application of polymeric material to tissue
EP0696185B1 (en) * 1993-04-28 1998-08-12 Focal, Inc. Apparatus, product and use related to intraluminal photothermoforming
GB2284606A (en) * 1993-11-24 1995-06-14 Aspid S A De C V Polymerised collagen-based anti-fibroid composition
US5705203A (en) 1994-02-07 1998-01-06 E. Khashoggi Industries Systems for molding articles which include a hinged starch-bound cellular matrix
US5776388A (en) 1994-02-07 1998-07-07 E. Khashoggi Industries, Llc Methods for molding articles which include a hinged starch-bound cellular matrix
US5843544A (en) 1994-02-07 1998-12-01 E. Khashoggi Industries Articles which include a hinged starch-bound cellular matrix
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
CA2185699A1 (en) * 1994-04-04 1995-10-12 William R. Freeman Use of phosphonylmethoxyalkyl nucleosides for the treatment of raised intraocular pressure
US5962477A (en) * 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
AU709134B2 (en) * 1994-05-02 1999-08-19 E.R. Squibb & Sons, Inc. Recombinant fibrin chains, fibrin and fibrin-homologs
US5665063A (en) * 1994-06-24 1997-09-09 Focal, Inc. Methods for application of intraluminal photopolymerized gels
US5583114A (en) * 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
USRE38827E1 (en) 1994-07-27 2005-10-11 3M Innovative Properties Company Adhesive sealant composition
US5660873A (en) * 1994-09-09 1997-08-26 Bioseal, Limited Liability Corporaton Coating intraluminal stents
US5989244A (en) * 1994-11-15 1999-11-23 Gregory; Kenton W. Method of use of a sheet of elastin or elastin-based material
US7001328B1 (en) * 1994-11-15 2006-02-21 Kenton W. Gregory Method for using tropoelastin and for producing tropoelastin biomaterials
US6087552A (en) * 1994-11-15 2000-07-11 Sisters Of Providence Of Oregon Method of producing fused biomaterials and tissue
US6372228B1 (en) 1994-11-15 2002-04-16 Kenton W. Gregory Method of producing elastin, elastin-based biomaterials and tropoelastin materials
AU697045B2 (en) * 1995-01-16 1998-09-24 Baxter International Inc. Self-supporting sheet-like material of cross-linked fibrin for preventing post- operative adhesions
AUPN066795A0 (en) * 1995-01-20 1995-02-16 Macquarie Research Limited Method of repair
US5510102A (en) * 1995-01-23 1996-04-23 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
GB9501579D0 (en) * 1995-01-27 1995-03-15 Univ Loughborough Effecting reactions
US5817303A (en) * 1995-05-05 1998-10-06 Protein Polymer Technologies, Inc. Bonding together tissue with adhesive containing polyfunctional crosslinking agent and protein polymer
USRE38730E1 (en) * 1995-05-05 2005-04-26 Harvest Technologies Corporation Automatic multiple-decanting centrifuge and method of treating physiological fluids
US5707331A (en) * 1995-05-05 1998-01-13 John R. Wells Automatic multiple-decanting centrifuge
US5713891A (en) * 1995-06-02 1998-02-03 Children's Medical Center Corporation Modified solder for delivery of bioactive substances and methods of use thereof
US5981621A (en) * 1996-02-29 1999-11-09 Closure Medical Corporation Monomeric compositions effective as wound closure devices
WO1996041864A1 (en) * 1995-06-13 1996-12-27 The Regents Of The University Of California Diode laser heated micro-reaction chamber with sample detection means
US5779673A (en) * 1995-06-26 1998-07-14 Focal, Inc. Devices and methods for application of intraluminal photopolymerized gels
SI9620106B (en) * 1995-08-29 2005-12-31 Fidia Advanced Biopolymers Srl Bio-materials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
JP2000510720A (en) * 1996-05-03 2000-08-22 ユーロス コーポレイション Pentosan polysulfate coating for medical devices
WO1998002098A1 (en) 1996-07-12 1998-01-22 Baxter International Inc. A fibrin delivery device and method for forming fibrin on a surface
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) * 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US6706690B2 (en) 1999-06-10 2004-03-16 Baxter Healthcare Corporation Hemoactive compositions and methods for their manufacture and use
US7871637B2 (en) 1996-08-27 2011-01-18 Baxter International Inc. Dry hemostatic compositions and methods for their preparation
US7320962B2 (en) 1996-08-27 2008-01-22 Baxter International Inc. Hemoactive compositions and methods for their manufacture and use
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
WO1998012274A1 (en) * 1996-09-23 1998-03-26 Chandrashekar Pathak Methods and devices for preparing protein concentrates
US7009034B2 (en) * 1996-09-23 2006-03-07 Incept, Llc Biocompatible crosslinked polymers
US20090324721A1 (en) * 1996-09-23 2009-12-31 Jack Kennedy Hydrogels Suitable For Use In Polyp Removal
US8003705B2 (en) * 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
FR2754268B1 (en) † 1996-10-07 1998-12-24 Dev Des Utilisations Du Collag ADHESIVE COMPOSITION BASED ON MACROMOLECULAR POLYALDEHYDE AND METHOD FOR CROSSLINKING COLLAGEN OR GELATIN
WO1998036707A1 (en) * 1997-02-07 1998-08-27 Sisters Of Providence In Oregon Method of producing biomaterials
CN1252102A (en) * 1997-02-19 2000-05-03 康乃尔研究基金会有限公司 DNA construct to confer multiple traits on plants
US6015474A (en) * 1997-06-20 2000-01-18 Protein Polymer Technologies Methods of using primer molecules for enhancing the mechanical performance of tissue adhesives and sealants
US5929044A (en) * 1997-08-14 1999-07-27 Cornell Research Foundation Protein solder composition and method of use
WO1999011202A1 (en) * 1997-09-05 1999-03-11 Icet, Inc. Biomimetic calcium phosphate implant coatings and methods for making the same
JP2001522863A (en) * 1997-11-07 2001-11-20 コンジュケム，インコーポレーテッド Novel conjugate of RGD-containing peptide and endogenous carrier
US6113636A (en) * 1997-11-20 2000-09-05 St. Jude Medical, Inc. Medical article with adhered antimicrobial metal
GB9727355D0 (en) 1997-12-24 1998-02-25 Kalibrant Limited A composition for use in fluorescence assay systems
GB2336207B (en) * 1997-12-24 2000-01-12 Kalibrant Limited A composition for use in fluorescence assay systems
US6724958B1 (en) 1998-01-23 2004-04-20 Science & Engineering Associates, Inc. Handheld laser system emitting visible non-visible radiation
US6348679B1 (en) 1998-03-17 2002-02-19 Ameritherm, Inc. RF active compositions for use in adhesion, bonding and coating
AU3475099A (en) * 1998-04-06 1999-10-25 Cornell Research Foundation Inc. Composition for tissue welding and method of use
JP3578627B2 (en) * 1998-05-15 2004-10-20 株式会社ホギメディカル Tissue sealant that promotes wound healing
US7122620B1 (en) 1998-05-27 2006-10-17 Medical Research Services And Development Ltd. Haptotactic peptides
IL139604A0 (en) * 1998-05-27 2002-02-10 Hadasit Med Res Service Novel peptides
US20020022588A1 (en) * 1998-06-23 2002-02-21 James Wilkie Methods and compositions for sealing tissue leaks
JP2002523136A (en) 1998-08-21 2002-07-30 プロビデンス ヘルス システム−オレゴン Insertable stent and method of making and using the stent
WO2000012018A1 (en) * 1998-08-26 2000-03-09 Advanced Closure Systems, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers or covering structures
US6986740B2 (en) * 1998-11-02 2006-01-17 Xantech Pharmaceuticals, Inc. Ultrasound contrast using halogenated xanthenes
BE1012536A3 (en) 1998-11-04 2000-12-05 Baxter Int Element with a layer fibrin its preparation and use.
US20020115066A1 (en) * 1998-11-26 2002-08-22 Hope Ralph Graham Viral therapeutics
EP1137373A4 (en) * 1998-12-04 2004-05-19 Chandrashekhar P Pathak Biocompatible crosslinked polymers
EP1140233A1 (en) * 1999-01-08 2001-10-10 David A. Browdie Tissue adhesive for treating vigorously bleeding surfaces
US6310036B1 (en) * 1999-01-09 2001-10-30 Last Chance Tissue Adhesives Corporation High strength, Bio-compatible tissue adhesive and methods for treating vigorously bleeding surfaces
US7615373B2 (en) * 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
WO2002018441A2 (en) * 2000-09-01 2002-03-07 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed fibrin-based matrices and tissues
US20040018226A1 (en) * 1999-02-25 2004-01-29 Wnek Gary E. Electroprocessing of materials useful in drug delivery and cell encapsulation
US20040116032A1 (en) * 1999-02-25 2004-06-17 Bowlin Gary L. Electroprocessed collagen
US20020081732A1 (en) * 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
GB9904722D0 (en) * 1999-03-03 1999-04-21 Murch Clifford R A tubular intraluminal graft
CN1238083C (en) 1999-04-12 2006-01-25 丰收技术股份有限公司 Method and apparatus for producing platelet rich plasma and/or platelet
US6312725B1 (en) * 1999-04-16 2001-11-06 Cohesion Technologies, Inc. Rapid gelling biocompatible polymer composition
WO2000072761A1 (en) 1999-05-29 2000-12-07 Tyco Health Care Group, Lp Bioabsorbable blends and surgical articles therefrom
US20050049178A1 (en) * 1999-07-06 2005-03-03 Oberschwabenklinik Gmbh Agent for the occlusion of blood vessels
GB9920732D0 (en) * 1999-09-03 1999-11-03 Sulzer Vascutek Ltd Sealant
US6351663B1 (en) 1999-09-10 2002-02-26 Akorn, Inc. Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation
US6944493B2 (en) * 1999-09-10 2005-09-13 Akora, Inc. Indocyanine green (ICG) compositions and related methods of use
US6783546B2 (en) 1999-09-13 2004-08-31 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6371984B1 (en) 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6183498B1 (en) 1999-09-20 2001-02-06 Devore Dale P. Methods and products for sealing a fluid leak in a tissue
US6649888B2 (en) 1999-09-23 2003-11-18 Codaco, Inc. Radio frequency (RF) heating system
US6391049B1 (en) 1999-10-06 2002-05-21 Board Of Regents The University Of Texas System Solid biodegradable device for use in tissue repair
AU7994800A (en) * 1999-10-08 2001-04-23 Providence Health System - Oregon Biocompatible albumin lamina and method
US6680063B1 (en) 1999-10-08 2004-01-20 Providence Health System-Oregon Biocompatible albumin lamina and method
GB9925380D0 (en) * 1999-10-28 1999-12-29 Tissuemed Ltd Flexible sheets for use in therapy
US6443976B1 (en) 1999-11-30 2002-09-03 Akorn, Inc. Methods for treating conditions and illnesses associated with abnormal vasculature
DE60137489D1 (en) * 2000-02-03 2009-03-12 Tissuemed Ltd DEVICE FOR CLOSING A SURGICAL PUNKING WOMAN
US6808707B2 (en) 2000-02-04 2004-10-26 Matrix Design Wound healing compositions and methods using tropoelastin and lysyl oxidase
GB0002719D0 (en) * 2000-02-08 2000-03-29 Tissuemed Ltd Thermal ablation of tissue
US8215314B2 (en) * 2000-02-11 2012-07-10 The General Hospital Corporation Photochemical tissue bonding
US7073510B2 (en) * 2000-02-11 2006-07-11 The General Hospital Corporation Photochemical tissue bonding
AU2001249984B2 (en) 2000-02-11 2005-05-26 The General Hospital Corporation Photochemical tissue bonding
JP3576063B2 (en) 2000-02-22 2004-10-13 株式会社ホギメディカル Soluble wound healing hemostatic cellulose fiber containing coagulation protein and method for producing the same
US6607522B1 (en) 2000-03-16 2003-08-19 General Hospital Corporation Methods for tissue welding using laser-activated protein solders
DE10015145A1 (en) * 2000-03-29 2001-10-11 Fraunhofer Ges Forschung Connector for vessel anastomosis comprises mesh metal inner sleeve covered by biocompatible biodegradable polymer outer sleeve to clamp vessel ends after laser shrinkage with retained flow section.
US6682760B2 (en) 2000-04-18 2004-01-27 Colbar R&D Ltd. Cross-linked collagen matrices and methods for their preparation
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
JP2002058736A (en) * 2000-08-17 2002-02-26 Seikagaku Kogyo Co Ltd Composition, medical instrument and kit for bone implantation
WO2002018546A2 (en) 2000-09-01 2002-03-07 Virginia Commonwealth University Intellectual Property Foundation Plasma-derived-fibrin-based matrices and tissue
US6726920B1 (en) 2000-09-22 2004-04-27 Durect Corporation Implantable drug delivery patch
ES2236314T3 (en) * 2000-10-23 2005-07-16 Tissuemed Limited HIDRATABLE SELF-ADHESIVE FAN FOR TOPICO THERAPEUTIC USE.
ES2409758T3 (en) * 2000-11-20 2013-06-27 Senorx, Inc. Tissue site markers for in vivo imaging
AU2002306558B2 (en) 2001-02-23 2007-06-28 The Scripps Research Institute Tryptophanyl-tRNA synthetase derived polypeptides useful for the regulation of angiogenesis
US8992567B1 (en) 2001-04-24 2015-03-31 Cardiovascular Technologies Inc. Compressible, deformable, or deflectable tissue closure devices and method of manufacture
US20080109030A1 (en) 2001-04-24 2008-05-08 Houser Russell A Arteriotomy closure devices and techniques
BR0209181A (en) 2001-04-24 2004-08-24 Cornell Res Foundation Inc Synthetic nucleic acid molecule for multiple traits
US8961541B2 (en) 2007-12-03 2015-02-24 Cardio Vascular Technologies Inc. Vascular closure devices, systems, and methods of use
US7025776B1 (en) 2001-04-24 2006-04-11 Advanced Catheter Engineering, Inc. Arteriotomy closure devices and techniques
US20030003157A1 (en) * 2001-06-06 2003-01-02 University Of Medicine & Dentistry Of New Jersey Collagen compositions and methods for making and using the same
US6623959B2 (en) 2001-06-13 2003-09-23 Ethicon, Inc. Devices and methods for cell harvesting
US7195774B2 (en) * 2001-08-29 2007-03-27 Carvalho Ricardo Azevedo Ponte Implantable and sealable system for unidirectional delivery of therapeutic agents to tissues
WO2003018673A1 (en) 2001-08-31 2003-03-06 Keratec Limited The production of biopolymer film, fibre, foam and adhesive materials from soluble s-sulfonated keratin derivatives
WO2003026481A2 (en) 2001-09-26 2003-04-03 Rice University Optically-absorbing nanoparticles for enhanced tissue repair
US6773699B1 (en) 2001-10-09 2004-08-10 Tissue Adhesive Technologies, Inc. Light energized tissue adhesive conformal patch
US6939364B1 (en) * 2001-10-09 2005-09-06 Tissue Adhesive Technologies, Inc. Composite tissue adhesive
US6780840B1 (en) 2001-10-09 2004-08-24 Tissue Adhesive Technologies, Inc. Method for making a light energized tissue adhesive
ATE434184T1 (en) * 2001-11-20 2009-07-15 Univ Duke INTERFACE BIOMATERIALS
US20050042240A1 (en) * 2002-01-28 2005-02-24 Utterberg David S. High viscosity antibacterials
US20030144362A1 (en) * 2002-01-28 2003-07-31 Utterberg David S. High viscosity antibacterials for cannulae
JP4551761B2 (en) 2002-06-10 2010-09-29 ケラテク リミテッド Keratin-derived orthopedic material
US10098981B2 (en) 2002-08-06 2018-10-16 Baxter International Inc. Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
CA2494295C (en) 2002-08-06 2012-05-01 Matrix Medical, Llc Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
US9101536B2 (en) * 2002-08-06 2015-08-11 Matrix Medical Llc Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
US8349348B2 (en) * 2002-08-06 2013-01-08 Matrix Medical, Llc Biocompatible phase invertible proteinaceous compositions and methods for making and using the same
DE10236152A1 (en) * 2002-08-07 2004-02-19 Marker Deutschland Gmbh Ski and ski binding combination
US7135027B2 (en) * 2002-10-04 2006-11-14 Baxter International, Inc. Devices and methods for mixing and extruding medically useful compositions
IL152609A0 (en) * 2002-11-03 2003-06-24 Hapto Biotech Inc Liposomal compositions comprising haptotactic peptides and uses thereof
EP1587551A2 (en) * 2003-01-24 2005-10-26 Rose-Hulman Institute of Technology Non-light activated adhesive composite, system, and methods
US7501133B2 (en) * 2003-01-24 2009-03-10 Rose-Hulman Institute Of Technology Light-activated adhesive composite, system, and methods of use thereof
US6939348B2 (en) 2003-03-27 2005-09-06 Cierra, Inc. Energy based devices and methods for treatment of patent foramen ovale
US7972330B2 (en) 2003-03-27 2011-07-05 Terumo Kabushiki Kaisha Methods and apparatus for closing a layered tissue defect
US8021362B2 (en) * 2003-03-27 2011-09-20 Terumo Kabushiki Kaisha Methods and apparatus for closing a layered tissue defect
US7165552B2 (en) * 2003-03-27 2007-01-23 Cierra, Inc. Methods and apparatus for treatment of patent foramen ovale
AU2004226374B2 (en) * 2003-03-27 2009-11-12 Terumo Kabushiki Kaisha Methods and apparatus for treatment of patent foramen ovale
US7293562B2 (en) * 2003-03-27 2007-11-13 Cierra, Inc. Energy based devices and methods for treatment of anatomic tissue defects
US7186251B2 (en) 2003-03-27 2007-03-06 Cierra, Inc. Energy based devices and methods for treatment of patent foramen ovale
JP2006523113A (en) * 2003-04-04 2006-10-12 ティシュームド リミテッド Tissue adhesive composition
US7273896B2 (en) * 2003-04-10 2007-09-25 Angiotech Pharmaceuticals (Us), Inc. Compositions and methods of using a transient colorant
US8834864B2 (en) * 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7311701B2 (en) * 2003-06-10 2007-12-25 Cierra, Inc. Methods and apparatus for non-invasively treating atrial fibrillation using high intensity focused ultrasound
WO2004110391A2 (en) * 2003-06-16 2004-12-23 Solx, Inc. Shunt for the treatment of glaucoma
US7129210B2 (en) * 2003-07-23 2006-10-31 Covalent Medical, Inc. Tissue adhesive sealant
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US7767756B2 (en) 2003-09-19 2010-08-03 Keraplast Technologies, Ltd. Composite materials containing keratin
US20070213768A1 (en) * 2003-10-21 2007-09-13 Irena Wasserman Compositions and Devices Including Same Useful for Anastomosis
US20050125015A1 (en) * 2003-12-04 2005-06-09 Mcnally-Heintzelman Karen M. Tissue-handling apparatus, system and method
US20050125033A1 (en) * 2003-12-04 2005-06-09 Mcnally-Heintzelman Karen M. Wound closure apparatus
DK1694370T3 (en) 2003-12-19 2012-12-10 Keratec Ltd Keratin-containing wound care products
CA2554165A1 (en) * 2004-01-22 2005-08-11 Solx, Inc. Glaucoma treatment method
CN104174071A (en) 2004-04-28 2014-12-03 安希奥设备国际有限责任公司 Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US7621952B2 (en) * 2004-06-07 2009-11-24 Dfine, Inc. Implants and methods for treating bone
US20060095138A1 (en) * 2004-06-09 2006-05-04 Csaba Truckai Composites and methods for treating bone
US7367975B2 (en) 2004-06-21 2008-05-06 Cierra, Inc. Energy based devices and methods for treatment of anatomic tissue defects
JP5113519B2 (en) * 2004-07-08 2013-01-09 ヌームアールエックス・インコーポレーテッド Treatment device, treatment method and material for pleural effusion
US20060024372A1 (en) * 2004-07-29 2006-02-02 Utterberg David S High viscosity antibacterials
AU2005268647B2 (en) * 2004-08-03 2011-04-14 Tissuemed Limited Tissue-adhesive materials
EP1796747B1 (en) 2004-08-27 2017-07-05 Antonio Lauto Bioadhesve film for tissue repair
US20060106459A1 (en) * 2004-08-30 2006-05-18 Csaba Truckai Bone treatment systems and methods
US20060094865A1 (en) * 2004-10-29 2006-05-04 Kapur Terri A Intraoperative method for isolating and concentrating autologous growth factors and for forming residual autologous growth factor compositions
US8048083B2 (en) 2004-11-05 2011-11-01 Dfine, Inc. Bone treatment systems and methods
JP2006158611A (en) * 2004-12-07 2006-06-22 Hamamatsu Univ School Of Medicine Indocyanine green quantitative catheter system
EP1846505B1 (en) * 2005-02-09 2015-11-11 Covidien LP Synthetic sealants
US7825083B2 (en) * 2005-02-10 2010-11-02 Spine Wave, Inc. Synovial fluid barrier
US7579317B2 (en) 2005-03-11 2009-08-25 Keratec, Ltd. Nutraceutical composition comprising soluble keratin or derivative thereof
AU2006235506B2 (en) * 2005-04-11 2011-06-30 Terumo Kabushiki Kaisha Methods and apparatus to achieve a closure of a layered tissue defect
US10357328B2 (en) 2005-04-20 2019-07-23 Bard Peripheral Vascular, Inc. and Bard Shannon Limited Marking device with retractable cannula
US8066712B2 (en) * 2005-09-01 2011-11-29 Dfine, Inc. Systems for delivering bone fill material
US8133336B2 (en) 2006-02-03 2012-03-13 Tissuemed Limited Tissue-adhesive materials
US20070233250A1 (en) * 2006-02-07 2007-10-04 Shadduck John H Systems for treating bone
DE102006011211A1 (en) * 2006-03-02 2007-09-06 Ossacur Ag Material for the treatment of bone and / or cartilage defects
MX2008014847A (en) * 2006-05-31 2009-04-30 Baxter Int Method for directed cell in-growth and controlled tissue regeneration in spinal surgery.
US20080026032A1 (en) * 2006-07-27 2008-01-31 Zubery Yuval Composite implants for promoting bone regeneration and augmentation and methods for their preparation and use
TWI436793B (en) 2006-08-02 2014-05-11 Baxter Int Rapidly acting dry sealant and methods for use and manufacture
DK2099400T3 (en) 2006-12-06 2014-10-20 Weber Jeffrey A BONE SPACES AND METHOD OF PRODUCING THEREOF
US20080140069A1 (en) * 2006-12-07 2008-06-12 Cierra, Inc. Multi-electrode apparatus for tissue welding and ablation
US8124735B2 (en) 2006-12-11 2012-02-28 Keraplast Technologies, Ltd. Porous keratin construct and method of making the same
US20080188858A1 (en) * 2007-02-05 2008-08-07 Robert Luzzi Bone treatment systems and methods
US20090227981A1 (en) * 2007-03-05 2009-09-10 Bennett Steven L Low-Swelling Biocompatible Hydrogels
US20090227689A1 (en) * 2007-03-05 2009-09-10 Bennett Steven L Low-Swelling Biocompatible Hydrogels
PL2136850T3 (en) 2007-04-13 2012-07-31 Kuros Biosurgery Ag Polymeric tissue sealant
US8092837B2 (en) * 2007-04-27 2012-01-10 Biomet Manufacturing Corp Fibrin based glue with functionalized hydrophilic polymer protein binding agent
EP2011524A1 (en) 2007-07-02 2009-01-07 Omrix Biopharmaceuticals Ltd. Fibrin glue with a visualization agent
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
GB0715514D0 (en) * 2007-08-10 2007-09-19 Tissuemed Ltd Coated medical devices
US10500309B2 (en) * 2007-10-05 2019-12-10 Cook Biotech Incorporated Absorbable adhesives and their formulation for use in medical applications
US8790698B2 (en) 2007-10-30 2014-07-29 Baxter International Inc. Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects
EP2219555B9 (en) 2007-12-03 2015-12-23 Tenaxis Medical, Inc. Biocompatible phase invertible proteinaceous compositions
US20090155197A1 (en) * 2007-12-14 2009-06-18 Smith Molly K Goniochromic indicator for skin sealant
US8487021B2 (en) * 2008-02-01 2013-07-16 Dfine, Inc. Bone treatment systems and methods
US9445854B2 (en) * 2008-02-01 2016-09-20 Dfine, Inc. Bone treatment systems and methods
EP2259803B2 (en) 2008-02-29 2019-03-13 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
ES2588383T5 (en) 2008-09-16 2020-04-22 Mayo Found Medical Education & Res Compositions that have platelet contents
CA2742765C (en) 2008-12-30 2016-04-12 C.R. Bard Inc. Marker delivery device for tissue marker placement
EP2396070A4 (en) 2009-02-12 2012-09-19 Incept Llc Drug delivery through hydrogel plugs
WO2010118312A2 (en) 2009-04-09 2010-10-14 Cardiovascular Systems, Inc. Tissue closure devices, device and systems for delivery, kits and methods therefor
US9155815B2 (en) * 2009-04-17 2015-10-13 Tenaxis Medical, Inc. Biocompatible phase invertible proteinaceous compositions and methods for making and using the same
WO2010129258A2 (en) 2009-04-27 2010-11-11 Mallinckrodt Inc. Tissue sealant compositions, vascular closure devices, and uses thereof
WO2010132673A1 (en) 2009-05-13 2010-11-18 Keraplast Technologies, Ltd. Biopolymer materials
US9039783B2 (en) * 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
KR101699992B1 (en) * 2009-06-16 2017-01-26 백스터 인터내셔널 인코포레이티드 Hemostatic sponge
EP2512535A1 (en) 2009-12-16 2012-10-24 Baxter International Inc Hemostatic sponge
US8617157B2 (en) 2010-01-26 2013-12-31 Covidien Lp Hernia repair system
SA111320355B1 (en) 2010-04-07 2015-01-08 Baxter Heathcare S A Hemostatic sponge
CA2801118C (en) 2010-06-01 2016-01-05 Baxter International Inc. Process for making dry and stable hemostatic compositions
BR112012030457B1 (en) 2010-06-01 2021-03-09 Baxter International Inc. process for making a dry and stable hemostatic composition, final finished container, method for providing a ready-to-use hemostatic composition, and kit for administering a hemostatic composition
EP2575775B1 (en) 2010-06-01 2018-04-04 Baxter International Inc. Process for making dry and stable hemostatic compositions
US20130211194A1 (en) 2010-10-05 2013-08-15 Robert A. Guyton Devices, systems, and methods for improving access to cardiac and vascular chambers
US11730760B2 (en) 2011-04-01 2023-08-22 The Bioregentech Institute, Inc. Laser assisted wound healing protocol and system
WO2012135808A2 (en) * 2011-04-01 2012-10-04 The Johns Hopkins University Intraoperative and blood-derived adhesives
US11389663B2 (en) 2011-04-01 2022-07-19 Bioregentech, Inc. Laser assisted wound healing protocol and system
KR102102002B1 (en) 2011-10-11 2020-04-20 백스터 인터내셔널 인코포레이티드 Hemostatic compositions
JP6195568B2 (en) 2011-10-11 2017-09-13 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ Hemostatic composition
PL2771027T3 (en) 2011-10-27 2016-01-29 Baxter Int Hemostatic compositions
US8999376B2 (en) 2012-02-03 2015-04-07 Xcede Technologies, Inc. Tissue patch
SG10201604810UA (en) 2012-02-07 2016-08-30 Global Bio Therapeutics Inc Compartmentalized method of nucleic acid delivery and compositions and uses thereof
IN2014DN08122A (en) 2012-03-06 2015-05-01 Ferrosan Medical Devices As
US11116841B2 (en) 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
US20130281913A1 (en) * 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
EP2977066A3 (en) 2012-06-12 2016-07-27 Ferrosan Medical Devices A/S Dry haemostatic composition
US10549112B2 (en) 2012-07-20 2020-02-04 The General Hospital Corporation Apparatus for tissue irradiation and methods and kits utilizing the same
US10292381B2 (en) 2012-07-20 2019-05-21 The General Hospital Corporation Vessel treatment systems, methods, and kits
WO2014015274A1 (en) 2012-07-20 2014-01-23 The General Hospital Corporation Methods for tissue passivation
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
CA2912357C (en) 2013-06-21 2019-12-31 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
CA2916337C (en) 2013-07-03 2022-03-22 Klox Technologies Inc. Biophotonic compositions comprising a chromophore and a gelling agent for treating wounds
CA2918539A1 (en) 2013-07-18 2015-01-22 The General Hospital Corporation Vessel treatment systems, methods, and kits
US11364032B2 (en) 2013-08-08 2022-06-21 Global Bio Therapeutics, Inc. Clamp device for minimally invasive procedures and uses thereof
WO2015089020A1 (en) * 2013-12-09 2015-06-18 Boston Scientific Scimed, Inc. Compositions, devices, kits and methods for attaching surgical meshes to tissue
EP3079731B1 (en) 2013-12-11 2018-08-08 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
US9655707B2 (en) 2014-02-06 2017-05-23 Boston Scientific Scimed, Inc. Methods, compositions, devices and kits for attaching surgical slings to tissue
MX2016012933A (en) 2014-04-01 2016-12-07 Klox Tech Inc Tissue filler compositions and methods of use.
WO2015175807A1 (en) 2014-05-16 2015-11-19 Mayo Foundation For Medical Education And Research Cell culture media compositions for primary cells
US11046818B2 (en) 2014-10-13 2021-06-29 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
BR112017008849B1 (en) 2014-10-31 2022-05-24 Klox Technologies Inc Light-curable fiber, light-curable fabric and manufactured article
CN107206165B (en) 2014-12-24 2020-10-23 弗罗桑医疗设备公司 Syringe for holding and mixing first and second substances
AU2016261925B2 (en) 2015-05-12 2020-10-01 Incept, Llc Drug delivery from hydrogels
RU2717356C2 (en) 2015-07-03 2020-03-23 Ферросан Медикал Дивайсиз А/С Syringe for holding vacuum in storage state
US9540548B1 (en) 2015-08-07 2017-01-10 Xcede Technologies, Inc. Adhesive compositions and related methods
US9833538B2 (en) 2015-08-07 2017-12-05 Xcede Technologies, Inc. Adhesive compositions and related methods
US10588998B2 (en) 2015-08-07 2020-03-17 Xcede Technologies, Inc. Adhesive compositions and related methods
US11654293B2 (en) * 2016-11-10 2023-05-23 The Bioregentech Institute, Inc. Laser assisted wound healing protocol and system
WO2018089954A1 (en) 2016-11-10 2018-05-17 BioRegentech Laser assisted wound healing protocol and system
WO2019135237A1 (en) * 2018-01-04 2019-07-11 Ramot At Tel-Aviv University Ltd. Scaffold for tissue welding
US11801324B2 (en) 2018-05-09 2023-10-31 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition
WO2019231763A1 (en) 2018-05-27 2019-12-05 Christos Angeletakis Tissue adhesives and sealants using naturally derived aldehydes
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
TWI814462B (en) * 2021-08-24 2023-09-01 國立臺灣大學 Manufacturing method of hemostatic material and hemostatic material prepared thereby
CN113876997B (en) * 2021-09-27 2022-09-20 广东省科学院健康医学研究所 Albumin composite adhesive and preparation method thereof

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3438374A (en) * 1966-02-28 1969-04-15 Us Health Education & Welfare Method of bonding tissue surfaces and controlling hemorrhaging thereof using a tissue adhesive and hemostatic composition
GB1515963A (en) * 1975-07-15 1978-06-28 Massachusetts Inst Technology Crosslinked collagen-mucopolysaccharide composite materials
US4280954A (en) * 1975-07-15 1981-07-28 Massachusetts Institute Of Technology Crosslinked collagen-mucopolysaccharide composite materials
US4122853A (en) * 1977-03-14 1978-10-31 Spectra-Med Infrared laser photocautery device
US4167045A (en) * 1977-08-26 1979-09-11 Interface Biomedical Laboratories Corp. Cardiac and vascular prostheses
AT359653B (en) * 1979-02-15 1980-11-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
AT359652B (en) * 1979-02-15 1980-11-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
CA1213520A (en) * 1982-03-17 1986-11-04 Abe Widra Hydrophilic biopolymeric copolyelectrolytes, and biodegradable dressings comprising same
US4550238A (en) * 1982-11-05 1985-10-29 Warner-Lambert Company Apparatus and method for sealing capsules
US4672969A (en) * 1983-10-06 1987-06-16 Sonomo Corporation Laser healing method
US4854320A (en) * 1983-10-06 1989-08-08 Laser Surgery Software, Inc. Laser healing method and apparatus
IL74179A (en) * 1984-01-30 1992-05-25 Meadox Medicals Inc Collagen synthetic vascular graft
JPH06102628B2 (en) * 1984-03-27 1994-12-14 イムノ・アクチエンゲゼルシャフト Tissue adhesive manufacturing method
JPS6131142A (en) * 1984-07-25 1986-02-13 富士写真光機株式会社 Blood vessel anastomosis laser probe
US4633870A (en) * 1985-06-26 1987-01-06 Sauer Jude S Apparatus for effecting anastomosis of tubular tissue by laser welding
US4676790A (en) * 1985-09-25 1987-06-30 Kern Seymour P Method of manufacture and implantation of corneal inlays
US4657820A (en) * 1986-04-16 1987-04-14 Gregory Halpern Plastic article containing a top coat comprising an albumin and polysaccharide mixture
CA1294546C (en) * 1986-04-23 1992-01-21 John S. Sundsmo Wound healing composition containing collagen
EP0246638A3 (en) * 1986-05-23 1989-03-15 Cordis Corporation Biologically modified synthetic grafts
CH673117A5 (en) * 1986-12-10 1990-02-15 Ajinomoto Kk
JPS6485272A (en) * 1986-12-10 1989-03-30 Ajinomoto Kk Adhesive
US4782819A (en) * 1987-02-25 1988-11-08 Adair Edwin Lloyd Optical catheter
JPH01124465A (en) * 1987-11-10 1989-05-17 Kanegafuchi Chem Ind Co Ltd Composition for artificial basement membrane and implantation device with artificial basement membrane
JPH01265970A (en) * 1988-04-19 1989-10-24 Shiseido Co Ltd Collagen water solution or water dispersion solution including hyaluronic acid
AT397203B (en) * 1988-05-31 1994-02-25 Immuno Ag FABRIC ADHESIVE
US4950483A (en) * 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production

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