CA2093132A1 - Process for the preparation of imidazo[4,5-c]quinolin-4-amines - Google Patents

Process for the preparation of imidazo[4,5-c]quinolin-4-amines

Info

Publication number
CA2093132A1
CA2093132A1 CA002093132A CA2093132A CA2093132A1 CA 2093132 A1 CA2093132 A1 CA 2093132A1 CA 002093132 A CA002093132 A CA 002093132A CA 2093132 A CA2093132 A CA 2093132A CA 2093132 A1 CA2093132 A1 CA 2093132A1
Authority
CA
Canada
Prior art keywords
imidazo
quinolin
amines
preparation
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002093132A
Other languages
French (fr)
Other versions
CA2093132C (en
Inventor
John F. Gerster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicis Pharmaceutical Corp
Original Assignee
John F. Gerster
Minnesota Mining And Manufacturing Company
The Minnesota Mining & Manufacturing Company
3M Company
Graceway Pharmaceuticals, Llc
Medicis Pharmaceutical Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John F. Gerster, Minnesota Mining And Manufacturing Company, The Minnesota Mining & Manufacturing Company, 3M Company, Graceway Pharmaceuticals, Llc, Medicis Pharmaceutical Corporation filed Critical John F. Gerster
Publication of CA2093132A1 publication Critical patent/CA2093132A1/en
Application granted granted Critical
Publication of CA2093132C publication Critical patent/CA2093132C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A process is disclosed for preparing 1-substituted-1H-imidazo[4,5-c]quinolin-4-amines of formula (I). The process involves reacting a 1-substituted-1H-imidazo[4,5-c]quinoline-5-oxide with an acylating agent and reacting the product thereof with an ami-nating agent.
CA002093132A 1990-10-05 1991-09-13 Process for the preparation of imidazo[4,5-c]quinolin-4-amines Expired - Lifetime CA2093132C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59307890A 1990-10-05 1990-10-05
US593,078 1990-10-05
PCT/US1991/006682 WO1992006093A1 (en) 1990-10-05 1991-09-13 Process for the preparation of imidazo[4,5-c]quinolin-4-amines

Publications (2)

Publication Number Publication Date
CA2093132A1 true CA2093132A1 (en) 1992-04-06
CA2093132C CA2093132C (en) 2002-02-26

Family

ID=24373289

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002093132A Expired - Lifetime CA2093132C (en) 1990-10-05 1991-09-13 Process for the preparation of imidazo[4,5-c]quinolin-4-amines

Country Status (11)

Country Link
US (1) US5367076A (en)
EP (1) EP0553202B1 (en)
AT (1) ATE121088T1 (en)
CA (1) CA2093132C (en)
DE (1) DE69108920T2 (en)
DK (1) DK0553202T3 (en)
ES (1) ES2071340T3 (en)
HU (1) HU217080B (en)
IE (1) IE70302B1 (en)
NZ (1) NZ239873A (en)
WO (1) WO1992006093A1 (en)

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* Cited by examiner, † Cited by third party
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DE69108920D1 (en) 1995-05-18
CA2093132C (en) 2002-02-26
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HUT63416A (en) 1993-08-30
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DK0553202T3 (en) 1995-07-03
US5367076A (en) 1994-11-22
DE69108920T2 (en) 1995-11-30
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HU9300965D0 (en) 1993-06-28
ES2071340T3 (en) 1995-06-16

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