CA2097573A1 - Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and method - Google Patents
Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and methodInfo
- Publication number
- CA2097573A1 CA2097573A1 CA002097573A CA2097573A CA2097573A1 CA 2097573 A1 CA2097573 A1 CA 2097573A1 CA 002097573 A CA002097573 A CA 002097573A CA 2097573 A CA2097573 A CA 2097573A CA 2097573 A1 CA2097573 A1 CA 2097573A1
- Authority
- CA
- Canada
- Prior art keywords
- ablation
- catheter
- heart
- distal extremity
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000002679 ablation Methods 0.000 title claims abstract description 133
- 238000013507 mapping Methods 0.000 title claims abstract description 27
- 238000000034 method Methods 0.000 title claims description 17
- 239000000523 sample Substances 0.000 claims abstract description 44
- 206010003119 arrhythmia Diseases 0.000 claims abstract description 13
- 230000006793 arrhythmia Effects 0.000 claims abstract description 13
- 239000004020 conductor Substances 0.000 claims description 18
- 239000000126 substance Substances 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 7
- 239000000835 fiber Substances 0.000 claims description 5
- 238000005452 bending Methods 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 2
- 238000009413 insulation Methods 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 210000005240 left ventricle Anatomy 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 229910001000 nickel titanium Inorganic materials 0.000 description 1
- 238000007674 radiofrequency ablation Methods 0.000 description 1
- 210000005245 right atrium Anatomy 0.000 description 1
- 210000005241 right ventricle Anatomy 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0133—Tip steering devices
- A61M25/0158—Tip steering devices with magnetic or electrical means, e.g. by using piezo materials, electroactive polymers, magnetic materials or by heating of shape memory materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
- A61B2017/003—Steerable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/0016—Energy applicators arranged in a two- or three dimensional array
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00184—Moving parts
- A61B2018/00196—Moving parts reciprocating lengthwise
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/00267—Expandable means emitting energy, e.g. by elements carried thereon having a basket shaped structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00351—Heart
- A61B2018/00357—Endocardium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00505—Urinary tract
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00839—Bioelectrical parameters, e.g. ECG, EEG
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0133—Tip steering devices
- A61M25/0147—Tip steering devices with movable mechanical means, e.g. pull wires
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2201/00—Properties
- C08L2201/12—Shape memory
Abstract
ABSTRACT OF THE DISCLOSURE
Endocardial mapping and ablation system for introduction into a chamber of a heart formed by a wall and having a passage leading thereto. The system is comprised of a catheter probe having a distal extremity. A plurality of electrodes are carried by the distal extremity for mapping the wall of the chamber. An ablation catheter is provided having a distal extremity. The ablation catheter has control means whereby the distal extremity can be bent separately of movement of the catheter probe to come into close proximity to the wall of the heart. The distal extremity of the ablation catheter is provided with capabilities for ablating a portion of the wall of the heart to eliminate an arrhythmia in the heart.
Endocardial mapping and ablation system for introduction into a chamber of a heart formed by a wall and having a passage leading thereto. The system is comprised of a catheter probe having a distal extremity. A plurality of electrodes are carried by the distal extremity for mapping the wall of the chamber. An ablation catheter is provided having a distal extremity. The ablation catheter has control means whereby the distal extremity can be bent separately of movement of the catheter probe to come into close proximity to the wall of the heart. The distal extremity of the ablation catheter is provided with capabilities for ablating a portion of the wall of the heart to eliminate an arrhythmia in the heart.
Description
ENDOCARDIAL NAPPING AND ABLATION SYS~EM
UTILIZING A ~EPARATELY CONTROLLED ABLATION CATHETER
AND NE~HOD
Inventor: Mir A. Imran This invention relates to an endocardial mapping and ablation system utilizing a separately controlled ablation catheter.
In co-pending application Serial No. 07/656,764 filed February 15, 1991, now U.S. Patent No. S,156,161, there is disclosed an endocardial mapping and/or ablation system which includes a plurality of longitudinally and radially spaced apart electrodes which are utilized for mapping and also which can be utilized for ablation. However, a need has arisen whereby it is desirable to be able to provide ablation which is independent of the electrodes carried by the mapping and or ablation system. There is therefore a need for a new and improved endocardial mapping and/or ablation system which overcomes this disadvantage.
In general, it is an object of the present invention to provide an endocardial mapping and ablation system and method which utilizes a separately controlled ablation catheter.
Another object of the invention is to provide a system, catheter and method of the above character in which the distal extremity of the ablation catheter can be independently controlled.
Another object of the invention is to provide a system, catheter and method of the above character in which once the site where the arrhythmia originates has been located, the ablation catheter can be steered separately to that location to perform an ablation.
Another object of the invention is to provide a system, catheter and method of the above character in which radio~
frequency energy can be delivered to perform the ablation.
Another object of the invention is to provide a system, catheter and method of the above character in which laser energy can be delivered to perform the ablation.
Another object of the invention is to provide a system, catheter and method of the above character which can be utilized for delivering pulse laser energy for performing the ablation.
Another object of the invention is to provide a system, catheter and method of the above character which includes a cannula for delivering a chemical into the heart muscle to perform the desired ablation.
Another object of the invention is to provide a system, catheter and method of the above character in which ablation can be accomplished without interfering with an electrocardiogram.
Additional objects and features of the invention will v appear from the following description in which the preferred embodiments are set forth in detail in conjunction with the accompanying drawings.
2SFigure 1 is a side elevational view of an endocardial mapping and ablation system utilizing a separately controlled ; ablation catheter incorporating the present invention.
Figure 2 is a cross-sectional view taken along the line 2-2 of Figure 1.
30Figure 3 is a cross-sectional view taken along the line 3-3 of Figure 1.
Figure 4 is a cross-sectional view similar to Figure 3 showing the use of an ablation catheter which has a capability of delivering pulsed laser energy for ablation.
35Figure S is a cross-sectional view also similar to Figure 3 which shows the use of a retractable cannula for delivery of a chemical for ablation.
In general, the endocardial mapping and ablationsystem with a separately controlled ablation catheter is for ,.~
,:,: . . : . . :. : ,: , , : . ,: :. ',. .. . :~ : : :.,~: .
~g 7 ~
introduction into a chamber of the heart of a patient with the heart being formed by a wall and with the heart having a passage leading to the chamber. A catheter probe is provided which has proximal and distal extremities. A
plurality of electrodes are carried by the distal extremity of the catheter probe for mapping the wall of the chamber.
An ablation catheter is provided with its distal extremity being disposed in the distal extremity of the catheter probe.
Control means is provided for the ablation catheter whereby the distal extremity can be moved independently and separately of movement of the catheter probe to move the distal extremity into close proximity to the wall of the heart. Means is carried by the distal extremity of the ablation catheter for performing an ablation operation in the desired location in the wall of the heart.
More in particular, the mapping and ablation system 11 of the present invention consists of a catheter probe 12 and an ablation catheter 13. The catheter probe 12 is described in detail in co-pending application Serial No.
07l656,764 filed February 15, 1991, now U.S. Patent No.
5,156,161. As described therein, it is comprised of a flexible elongate member 16 formed of a suitable material such as plastic which is provided with proximal and distal extremities 17 and 18. The flexible elongate member 16 is provided with a centrally disposed lumen 21 extending the length thereof. It should be appreciated that although the lumen 21 is shown as being centrally disposed, it can be offset if desired. Also, it is provided with a plurality of additional lumens such as lumens 22 and 23, which also extend the length of the flexible elongate member 16. If desired, still further additional lumens can be provided.
As described in said co-pending application Serial No.
07/656,764 filed February 15, 1991, now U.S. Patent No.
5,156,161, the catheter probe 12 includes a plurality of longitudinally and radially spaced apart electrodes 26.
Expandable means 27 is secured to the distal extremity of the flexible elongate member 16 for mounting the electrodes 26. The expandable means 27 as shown is formed of a plurality of flexible arms 28 which are movable between a : . .
: :
: . . ~: -:
2 ~
contracted position and an expanded position. The proximal extremities of the arms 28 are secured to the distal extremity of the flexible elongate member 16. The distal extremities of the arms 16 are secured within a cylindrical tip 29 which is provided with a rounded or hemispherical distal extremity.
Means is provided for moving the expandable means 27 between expanded and contracted positions and consists of a pull wire 31 which has its distal extremity secured within the cylindrical tip 29 and which extends between the arms 28 through the lumen 22 of the flexible elongate member 16, out the distal extremity of the member 16. This permits manual operation of the pull wire 31 exterior of the human body containing the heart. The movement of the distal extremity of the expandable means 27 in moving from an expanded position to a contracted dotted-line position is shown in Figure 1. It can be seen that by pulling on the pull wire 31, the tip 29 is pulled rearwardly or to the left as viewed in Figure 1 to cause expansion of the expandable means whereby pushing of the pull wire 31 forwardly or to the right as viewed in Figure 1 will cause contraction of the same.
The electrodes 26 are connected to conductors 34 provided in a cable 36 which extends through the lumen 23 of the flexible elongate member 16. The cable 36 is connected to a computer 37 which is provided with a video screen 38.
The ablation catheter 13 is a separate component and is slidably mounted in the lumen 21 of the flexible elongate member 16 of the catheter probe 12. Alternatively, it can be positioned independently of the catheter probe 12 along side the catheter probe 12. The ablation catheter 13 is comprised of a flexible elongate member 41 formed of a suitable material such as a medical grade plastic. It is provided with a centrally disposed or larger lumen 42 and six additional lumens 42-48 which are generally equally circumferentially spaced around the central lumen 42. The lumens 43, 45 and 47 are offset by approximately 120 with xespect to each other. A conductor 51 of a suitable , :
;,,: . ~
:-:
5 ~
conductinq material such as copper and covered by aninsulating layer 52 is disposed in the central lumen 42 and, when RF energy is used for ablation, is connected to a hemispheric electrode 54 mounted on the tip or distal extremity 56 of the flexible elongate member 41. This same conductor can also be utilized for sensing for an electrocardiogram. This conductor 51 can also serve as a stiffening element for the flexible elongate member 41, if that is desired.
The flexible elongate member 41 is provided with a proximal extremity through which the conductor 51 extends, which can be connected to the computer 37 and, alternatively or in addition, to a power supply and control console 61 as shown by the dotted lines.
Means is provided for causing bending movement of the distal extremity of the flexible elongate member 41 and consists of flexible elongate elements 63, 65 and 67 which are disposed in the lumens 43, 45 and 47. These flexible elongate elements are formed of a material having a negative coefficient of expansion and are of the type described in co-pending application Serial No. 07/793,858 filed November 18, 1991. As described therein, one material suitable for this purpose is a nickel titanium alloy manufactured and sold under the trademark Flexinol by Toki ; 25 of Japan. As explained in said co-pending application, the heating of the Flexinol wire changes its crystalline structure causing it to shorten itself, or in other words to have a negative coefficient of expansion upon the application of heat to the æame. These elements 63, 65 and 67 can be heated by passing electrical current therethrough.
This is accomplished by the use of three separate conductors 73, 75 and 77 which are bonded to the proximal extremities of the flexible elongate elements 63, 65 and 67 in the manner described in co-pending application Serial No. 07/793,858 filed November 18, 1991. The conductors 73, 75 and 77 are provided with insulation 78 and are disposed in the lumens 43, 45 and 47. All of them are connected to the power supply and control console 61.
.
. - ,:
. : : .. : :,.:: . : ::
~ . , ~ . !
. . ' .'. ' -6 2 ~ ~ 7 ~ u~ 3 The distal extremities of the flexible elongate elements 63, 65 and 67 are bonded together in a suitable manner and are connected to a ground conductor 81 having insulation 82 thereon. The conductor 81 is disposed in the lumen 46 and extends the length thereof. It is also connected to the power supply and control console 61 to provide a ground return for the flexible elongate elements 63, 65 and 67.
Operation and use of the endocardial mapping and ablation system utilizing a separately controlled ablation catheter and the method of using the same may be briefly described as follows. The system is used in a conventional manner as described in co-pending application Serial No.
07/656,764 filed February 15, 1991, now U.S. Patent No.
5,156,161. The catheter probe 12 can be introduced through the superior and inferior vena cavae into the right atrium and then advanced into the right ventricle, assuming that is the desired cavity of the heart (not shown) or into the left ventricle via the aorta. The cavity is formed by a wall of the heart and has a passage leading thereto as hereinbefore described. The pull wire 31 is then pulled to cause the expandable means 27 with the electrodes 26 carried thereby to be moved into engagement with the wall of the heart. The computer 37 is then utilized to map the various potentials within the wall forming the cavity of the heart and an isochronal map thereof is displayed on the computer screen 38. As soon as the focus of the arrhythmia has been located, the user, i.e. the physician, identifies the particular electrode of the electrodes 26 where ablation energy is to be delivered. Rather than delivering ablation energy through the selected electrode 26, ablation is achieved in the present invention by the use of the separately controlled ablation catheter 13.
The ablation catheter 13 is advanced through the lumen 21 by visualizing the same, as for example by visualizing ; 35 the tip electrode 54 with x-rays. It should be appreciated that if desired, additional markers can be provided on the tip if necessary to provide adequate visualization with x-rays. As the ablation catheter 13 is being advanced into the chamber of the heart and into the expandable means 27, - ,: , .: , . . --7~
it can be bent in the desired direction by the use of the control console 61 which is of the type described in co-pending application Serial No. 07/793,858 filed November 18, 1991. Operation of the control console 61 causes heating of the appropriate Flexinol wires 63, 65 and 67 to cause bending of the distal extremity 56 of the flexible elongate member 41 in the desired direction until the portion of the wall of the heart which is to be ablated is approached so that it is in close proximity or in contact therewith.
Typically the electrode 54 will be generally flush with the arm 28 which carries the electrode 26 in the closest proximity to the reqion to be ablated. As soon as the ablation catheter 13 has been manipulated so that the electrode 54 is in the desired position, ablation energy is caused to be delivered through the ablation conductor 51 to the electrode 54 and through the return ground conductor to create an ablation in the tissue of the wall of the heart which is the focus of the arrhythmia. By this ablation, the arrhythmia should be eliminated. Thereafter the ablation catheter 13 and the catheter probe 12 can be removed.
It should be appreciated that the distal extremity 56 of the ablation catheter can be bent in various directions extending about 360 of the longitudinal axis of the ablation catheter 13. In this way, it is possible for the distal extremity 56 of the separately controlled ablation catheter 13 to be moved into contact with any portion of the wall of the heart in the chamber in which the catheter probe 12 is disposed and contacted by one of the electrodes 26.
It should be appreciated that the computer 37 can be utilized for automatically power positioning the distal extremity of the ablation catheter 13. The computer collects the information from the electrodes 26 and expandable means 27 and displays them on the isochronal map on the computer screen 38 of the wall of the chamber of the heart in which the expandable means 27 is disposed. The physician utilizing the isochronal map identifies the particular electrodewhere ablation energy is to be delivered. The computer 37 operates ; , :
.: ..
-~: ~ ,., 8 ~ ~ 3 ~ ~ ~
- with the power supply 61 to manipulate the distal extremity of the ablation catheter to bring the distal extremity adjacent to the electrode selected by the physician. Once the distal extremity of the ablation catheter 13 is near the electrode selected by the physician, the computer starts matching the signal picked up from the tip of the ablation catheter 13 in the electrode selected on the expandable means 27. Once a match is achieved, radiofrequency ablation energy is delivered from the power supply 61 to the electrode 54 to cause the desired ablation to occur. After the ablation has been performed, the ablation catheter 13 and the catheter probe can be removed.
One of the principal advantages of utilizing a separately controlled ablation catheter 13 is that other means other than RF energy can be utilized for performing an ablation. For example, as shown in Figure 4, in place of the center conductor 51, a fiber optic 86 can be provided which extends through the lumen 42 with the lumen 42 extending through the distal extremity of the flexible elongate member 41 to permit pulsed laser energy to be delivered to the ablation site. By way of example, pulsed laser energy can be delivered from an excimer laser through pure silica fibers serving as the fiber optic 86 to deliver such pulsed energy to the ablation site. In such an arrangement, it may be desirable to place another conductor 87 in the lumen 44 which can serve as a conductor to an ECG
sensing electrode which can be connected into the computer 37.
Another alternative for delivering ablation means to the wall of the heart is shown in Figure 5 and consists of an ablation catheter 91 in which a retractable cannula 92 is disposed in the lumen 42. The retractable cannula can be of the type described in co-pending application Serial No. __ _ filed , 19_ . The cannula 92 can be advanced under the control of the control console 61 and, after an appropriate incision has been made into the tissue of the wall of the heart, a chemical can be introduced into the incision by utilizing the centrally disposed lumen provided centrally within the cannula 92. A controlled :: ' - ' - . .: . .
., ~'3~ ~3 amount of the chemical can be delivered to the desired site to cause the desired amount of ablation of tissue of the heart.
The means for ablation provided in Figures 4 and 5 has an advantage over the RF energy which is delivered in the embodiment shown in Figures 1, 2 and 3 because it makes it possible to observe the electrogram on the screen 38 during the time that the ablation is taking place, and to thereby ascertain when the arrhythmia disappears. This is generally not possible when radio frequency energy is used for ablation because the radio frequency interferes with the electrocardiogram being produced, so that it is difficult, if not impossible, to observe the same on the screen 38.
Thus it can be seen that there is a distinct advantage in using means other than RF energy for causing ablation in the wall of the heart.
In view of the foregoing, it can be seen that there has been provided an endocardial mapping and ablation system utilizing a separately controlled ablation catheter which facilitates performing precise ablations after the mapping operation has been completed. By the use of chemicals and/or laser energy, it is possible to perform such ablations while observing the electrocardiogram, thereby giving the physician the opportunity to ascertain when ablation should be discontinued by noticing the disappearance of the arrhythmia.
:, . . . . . .
,., . ~ . . ..
"
,, . :: : ., ... ~
: :,: ~
: . :
UTILIZING A ~EPARATELY CONTROLLED ABLATION CATHETER
AND NE~HOD
Inventor: Mir A. Imran This invention relates to an endocardial mapping and ablation system utilizing a separately controlled ablation catheter.
In co-pending application Serial No. 07/656,764 filed February 15, 1991, now U.S. Patent No. S,156,161, there is disclosed an endocardial mapping and/or ablation system which includes a plurality of longitudinally and radially spaced apart electrodes which are utilized for mapping and also which can be utilized for ablation. However, a need has arisen whereby it is desirable to be able to provide ablation which is independent of the electrodes carried by the mapping and or ablation system. There is therefore a need for a new and improved endocardial mapping and/or ablation system which overcomes this disadvantage.
In general, it is an object of the present invention to provide an endocardial mapping and ablation system and method which utilizes a separately controlled ablation catheter.
Another object of the invention is to provide a system, catheter and method of the above character in which the distal extremity of the ablation catheter can be independently controlled.
Another object of the invention is to provide a system, catheter and method of the above character in which once the site where the arrhythmia originates has been located, the ablation catheter can be steered separately to that location to perform an ablation.
Another object of the invention is to provide a system, catheter and method of the above character in which radio~
frequency energy can be delivered to perform the ablation.
Another object of the invention is to provide a system, catheter and method of the above character in which laser energy can be delivered to perform the ablation.
Another object of the invention is to provide a system, catheter and method of the above character which can be utilized for delivering pulse laser energy for performing the ablation.
Another object of the invention is to provide a system, catheter and method of the above character which includes a cannula for delivering a chemical into the heart muscle to perform the desired ablation.
Another object of the invention is to provide a system, catheter and method of the above character in which ablation can be accomplished without interfering with an electrocardiogram.
Additional objects and features of the invention will v appear from the following description in which the preferred embodiments are set forth in detail in conjunction with the accompanying drawings.
2SFigure 1 is a side elevational view of an endocardial mapping and ablation system utilizing a separately controlled ; ablation catheter incorporating the present invention.
Figure 2 is a cross-sectional view taken along the line 2-2 of Figure 1.
30Figure 3 is a cross-sectional view taken along the line 3-3 of Figure 1.
Figure 4 is a cross-sectional view similar to Figure 3 showing the use of an ablation catheter which has a capability of delivering pulsed laser energy for ablation.
35Figure S is a cross-sectional view also similar to Figure 3 which shows the use of a retractable cannula for delivery of a chemical for ablation.
In general, the endocardial mapping and ablationsystem with a separately controlled ablation catheter is for ,.~
,:,: . . : . . :. : ,: , , : . ,: :. ',. .. . :~ : : :.,~: .
~g 7 ~
introduction into a chamber of the heart of a patient with the heart being formed by a wall and with the heart having a passage leading to the chamber. A catheter probe is provided which has proximal and distal extremities. A
plurality of electrodes are carried by the distal extremity of the catheter probe for mapping the wall of the chamber.
An ablation catheter is provided with its distal extremity being disposed in the distal extremity of the catheter probe.
Control means is provided for the ablation catheter whereby the distal extremity can be moved independently and separately of movement of the catheter probe to move the distal extremity into close proximity to the wall of the heart. Means is carried by the distal extremity of the ablation catheter for performing an ablation operation in the desired location in the wall of the heart.
More in particular, the mapping and ablation system 11 of the present invention consists of a catheter probe 12 and an ablation catheter 13. The catheter probe 12 is described in detail in co-pending application Serial No.
07l656,764 filed February 15, 1991, now U.S. Patent No.
5,156,161. As described therein, it is comprised of a flexible elongate member 16 formed of a suitable material such as plastic which is provided with proximal and distal extremities 17 and 18. The flexible elongate member 16 is provided with a centrally disposed lumen 21 extending the length thereof. It should be appreciated that although the lumen 21 is shown as being centrally disposed, it can be offset if desired. Also, it is provided with a plurality of additional lumens such as lumens 22 and 23, which also extend the length of the flexible elongate member 16. If desired, still further additional lumens can be provided.
As described in said co-pending application Serial No.
07/656,764 filed February 15, 1991, now U.S. Patent No.
5,156,161, the catheter probe 12 includes a plurality of longitudinally and radially spaced apart electrodes 26.
Expandable means 27 is secured to the distal extremity of the flexible elongate member 16 for mounting the electrodes 26. The expandable means 27 as shown is formed of a plurality of flexible arms 28 which are movable between a : . .
: :
: . . ~: -:
2 ~
contracted position and an expanded position. The proximal extremities of the arms 28 are secured to the distal extremity of the flexible elongate member 16. The distal extremities of the arms 16 are secured within a cylindrical tip 29 which is provided with a rounded or hemispherical distal extremity.
Means is provided for moving the expandable means 27 between expanded and contracted positions and consists of a pull wire 31 which has its distal extremity secured within the cylindrical tip 29 and which extends between the arms 28 through the lumen 22 of the flexible elongate member 16, out the distal extremity of the member 16. This permits manual operation of the pull wire 31 exterior of the human body containing the heart. The movement of the distal extremity of the expandable means 27 in moving from an expanded position to a contracted dotted-line position is shown in Figure 1. It can be seen that by pulling on the pull wire 31, the tip 29 is pulled rearwardly or to the left as viewed in Figure 1 to cause expansion of the expandable means whereby pushing of the pull wire 31 forwardly or to the right as viewed in Figure 1 will cause contraction of the same.
The electrodes 26 are connected to conductors 34 provided in a cable 36 which extends through the lumen 23 of the flexible elongate member 16. The cable 36 is connected to a computer 37 which is provided with a video screen 38.
The ablation catheter 13 is a separate component and is slidably mounted in the lumen 21 of the flexible elongate member 16 of the catheter probe 12. Alternatively, it can be positioned independently of the catheter probe 12 along side the catheter probe 12. The ablation catheter 13 is comprised of a flexible elongate member 41 formed of a suitable material such as a medical grade plastic. It is provided with a centrally disposed or larger lumen 42 and six additional lumens 42-48 which are generally equally circumferentially spaced around the central lumen 42. The lumens 43, 45 and 47 are offset by approximately 120 with xespect to each other. A conductor 51 of a suitable , :
;,,: . ~
:-:
5 ~
conductinq material such as copper and covered by aninsulating layer 52 is disposed in the central lumen 42 and, when RF energy is used for ablation, is connected to a hemispheric electrode 54 mounted on the tip or distal extremity 56 of the flexible elongate member 41. This same conductor can also be utilized for sensing for an electrocardiogram. This conductor 51 can also serve as a stiffening element for the flexible elongate member 41, if that is desired.
The flexible elongate member 41 is provided with a proximal extremity through which the conductor 51 extends, which can be connected to the computer 37 and, alternatively or in addition, to a power supply and control console 61 as shown by the dotted lines.
Means is provided for causing bending movement of the distal extremity of the flexible elongate member 41 and consists of flexible elongate elements 63, 65 and 67 which are disposed in the lumens 43, 45 and 47. These flexible elongate elements are formed of a material having a negative coefficient of expansion and are of the type described in co-pending application Serial No. 07/793,858 filed November 18, 1991. As described therein, one material suitable for this purpose is a nickel titanium alloy manufactured and sold under the trademark Flexinol by Toki ; 25 of Japan. As explained in said co-pending application, the heating of the Flexinol wire changes its crystalline structure causing it to shorten itself, or in other words to have a negative coefficient of expansion upon the application of heat to the æame. These elements 63, 65 and 67 can be heated by passing electrical current therethrough.
This is accomplished by the use of three separate conductors 73, 75 and 77 which are bonded to the proximal extremities of the flexible elongate elements 63, 65 and 67 in the manner described in co-pending application Serial No. 07/793,858 filed November 18, 1991. The conductors 73, 75 and 77 are provided with insulation 78 and are disposed in the lumens 43, 45 and 47. All of them are connected to the power supply and control console 61.
.
. - ,:
. : : .. : :,.:: . : ::
~ . , ~ . !
. . ' .'. ' -6 2 ~ ~ 7 ~ u~ 3 The distal extremities of the flexible elongate elements 63, 65 and 67 are bonded together in a suitable manner and are connected to a ground conductor 81 having insulation 82 thereon. The conductor 81 is disposed in the lumen 46 and extends the length thereof. It is also connected to the power supply and control console 61 to provide a ground return for the flexible elongate elements 63, 65 and 67.
Operation and use of the endocardial mapping and ablation system utilizing a separately controlled ablation catheter and the method of using the same may be briefly described as follows. The system is used in a conventional manner as described in co-pending application Serial No.
07/656,764 filed February 15, 1991, now U.S. Patent No.
5,156,161. The catheter probe 12 can be introduced through the superior and inferior vena cavae into the right atrium and then advanced into the right ventricle, assuming that is the desired cavity of the heart (not shown) or into the left ventricle via the aorta. The cavity is formed by a wall of the heart and has a passage leading thereto as hereinbefore described. The pull wire 31 is then pulled to cause the expandable means 27 with the electrodes 26 carried thereby to be moved into engagement with the wall of the heart. The computer 37 is then utilized to map the various potentials within the wall forming the cavity of the heart and an isochronal map thereof is displayed on the computer screen 38. As soon as the focus of the arrhythmia has been located, the user, i.e. the physician, identifies the particular electrode of the electrodes 26 where ablation energy is to be delivered. Rather than delivering ablation energy through the selected electrode 26, ablation is achieved in the present invention by the use of the separately controlled ablation catheter 13.
The ablation catheter 13 is advanced through the lumen 21 by visualizing the same, as for example by visualizing ; 35 the tip electrode 54 with x-rays. It should be appreciated that if desired, additional markers can be provided on the tip if necessary to provide adequate visualization with x-rays. As the ablation catheter 13 is being advanced into the chamber of the heart and into the expandable means 27, - ,: , .: , . . --7~
it can be bent in the desired direction by the use of the control console 61 which is of the type described in co-pending application Serial No. 07/793,858 filed November 18, 1991. Operation of the control console 61 causes heating of the appropriate Flexinol wires 63, 65 and 67 to cause bending of the distal extremity 56 of the flexible elongate member 41 in the desired direction until the portion of the wall of the heart which is to be ablated is approached so that it is in close proximity or in contact therewith.
Typically the electrode 54 will be generally flush with the arm 28 which carries the electrode 26 in the closest proximity to the reqion to be ablated. As soon as the ablation catheter 13 has been manipulated so that the electrode 54 is in the desired position, ablation energy is caused to be delivered through the ablation conductor 51 to the electrode 54 and through the return ground conductor to create an ablation in the tissue of the wall of the heart which is the focus of the arrhythmia. By this ablation, the arrhythmia should be eliminated. Thereafter the ablation catheter 13 and the catheter probe 12 can be removed.
It should be appreciated that the distal extremity 56 of the ablation catheter can be bent in various directions extending about 360 of the longitudinal axis of the ablation catheter 13. In this way, it is possible for the distal extremity 56 of the separately controlled ablation catheter 13 to be moved into contact with any portion of the wall of the heart in the chamber in which the catheter probe 12 is disposed and contacted by one of the electrodes 26.
It should be appreciated that the computer 37 can be utilized for automatically power positioning the distal extremity of the ablation catheter 13. The computer collects the information from the electrodes 26 and expandable means 27 and displays them on the isochronal map on the computer screen 38 of the wall of the chamber of the heart in which the expandable means 27 is disposed. The physician utilizing the isochronal map identifies the particular electrodewhere ablation energy is to be delivered. The computer 37 operates ; , :
.: ..
-~: ~ ,., 8 ~ ~ 3 ~ ~ ~
- with the power supply 61 to manipulate the distal extremity of the ablation catheter to bring the distal extremity adjacent to the electrode selected by the physician. Once the distal extremity of the ablation catheter 13 is near the electrode selected by the physician, the computer starts matching the signal picked up from the tip of the ablation catheter 13 in the electrode selected on the expandable means 27. Once a match is achieved, radiofrequency ablation energy is delivered from the power supply 61 to the electrode 54 to cause the desired ablation to occur. After the ablation has been performed, the ablation catheter 13 and the catheter probe can be removed.
One of the principal advantages of utilizing a separately controlled ablation catheter 13 is that other means other than RF energy can be utilized for performing an ablation. For example, as shown in Figure 4, in place of the center conductor 51, a fiber optic 86 can be provided which extends through the lumen 42 with the lumen 42 extending through the distal extremity of the flexible elongate member 41 to permit pulsed laser energy to be delivered to the ablation site. By way of example, pulsed laser energy can be delivered from an excimer laser through pure silica fibers serving as the fiber optic 86 to deliver such pulsed energy to the ablation site. In such an arrangement, it may be desirable to place another conductor 87 in the lumen 44 which can serve as a conductor to an ECG
sensing electrode which can be connected into the computer 37.
Another alternative for delivering ablation means to the wall of the heart is shown in Figure 5 and consists of an ablation catheter 91 in which a retractable cannula 92 is disposed in the lumen 42. The retractable cannula can be of the type described in co-pending application Serial No. __ _ filed , 19_ . The cannula 92 can be advanced under the control of the control console 61 and, after an appropriate incision has been made into the tissue of the wall of the heart, a chemical can be introduced into the incision by utilizing the centrally disposed lumen provided centrally within the cannula 92. A controlled :: ' - ' - . .: . .
., ~'3~ ~3 amount of the chemical can be delivered to the desired site to cause the desired amount of ablation of tissue of the heart.
The means for ablation provided in Figures 4 and 5 has an advantage over the RF energy which is delivered in the embodiment shown in Figures 1, 2 and 3 because it makes it possible to observe the electrogram on the screen 38 during the time that the ablation is taking place, and to thereby ascertain when the arrhythmia disappears. This is generally not possible when radio frequency energy is used for ablation because the radio frequency interferes with the electrocardiogram being produced, so that it is difficult, if not impossible, to observe the same on the screen 38.
Thus it can be seen that there is a distinct advantage in using means other than RF energy for causing ablation in the wall of the heart.
In view of the foregoing, it can be seen that there has been provided an endocardial mapping and ablation system utilizing a separately controlled ablation catheter which facilitates performing precise ablations after the mapping operation has been completed. By the use of chemicals and/or laser energy, it is possible to perform such ablations while observing the electrocardiogram, thereby giving the physician the opportunity to ascertain when ablation should be discontinued by noticing the disappearance of the arrhythmia.
:, . . . . . .
,., . ~ . . ..
"
,, . :: : ., ... ~
: :,: ~
: . :
Claims (21)
1. In an endocardial mapping and ablation system for introduction into a chamber of a heart formed by a wall and having a passage leading thereto, a catheter probe having a distal extremity, a plurality of electrodes carried by the distal extremity of the catheter probe for mapping the wall of the chamber, an ablation catheter carried by the catheter probe and having a distal extremity movable into the chamber, said ablation catheter having control means whereby the distal extremity can be bent independently of movement of the catheter probe while the distal extremity of the catheter probe is in the chamber to come into close proximity to the wall of the heart and means carried by the distal extremity of the ablation catheter for ablating a portion of the wall of the heart.
2. A system as in Claim 1 wherein said ablation catheter is provided with means for delivering RF energy for ablation.
3. A system as in Claim 1 wherein said ablation catheter is provided with means for delivering laser energy for causing ablation.
4. A system as in Claim 1 wherein said ablation catheter is provided with means for delivering a chemical for providing ablation.
5. A system as in Claim 4 wherein said means for delivering a chemical includes a retractable cannula.
6. In an endocardial mapping and ablation system for introduction into a chamber of a heart formed by a wall and having a passage leading thereto, a catheter probe having a distal extremity, a plurality of electrodes carried by the distal extremity of the catheter probe for mapping the wall of the chamber, an ablation catheter having a distal extremity movable into the chamber, said ablation catheter having control means whereby the distal extremity can be bent independently of movement of the catheter probe to come into close proximity to the wall of the heart and means carried by the distal extremity of the ablation catheter for ablating a portion of the wall of the heart, said catheter probe being provided with a lumen extending therethrough, said ablation catheter being slidably mounted in said lumen.
7. A system as in Claim 1 wherein said ablation catheter has a longitudinal axis and wherein said control means includes means for steering the distal extremity of the ablation catheter through an angle of 360° with respect to the longitudinal axis.
8. A system as in Claim 1 together with a computer connected to the catheter probe and to the ablation catheter for automatically bringing the distal extremity of the ablation catheter into the vicinity of a selected electrode of the plurality of electrodes for performing an ablation.
9. In an ablation catheter for introduction into a chamber of the heart, a flexible elongate member, said flexible elongate member having a centrally disposed lumen extending therethrough, said flexible elongate element having at least four additional lumens extending therethrough and generally surrounding the centrally disposed lumen, at least three of said additional lumens being spaced approximately 120° apart, a flexible elongate element having a negative coefficient of expansion disposed in each of said three additional lumens, and a ground return conductor disposed in another of said additional lumens, means connecting the distal extremities of the flexible elongate elements formed of a material having a negative coefficient of expansion to the ground return conductor and means including conductors connected to said flexible elongate elements of a material having a negative coefficient of expansion for supplying electrical energy to the same to cause bending of the distal extremity with respect to the longitudinal axis.
10. A catheter as in Claim 9 together with the electrode mounted on the distal extremity and connected to the ground return, and a conductor disposed in the central lumen and connected to the electrode for supplying radio frequency energy to the electrode.
11. A catheter as in Claim 9 together with a fiber optic disposed in the central lumen and means for delivering laser energy to the fiber optic to cause ablation.
12. A catheter as in Claim 9 together with a retractable cannula disposed within the central lumen and means for delivering a chemical to the distal extremity of the catheter through the central lumen.
13. In an endocardial mapping and ablation system for introduction into a chamber of the heart having blood therein and formed by a wall and having a passage leading thereto, a catheter probe having proximal and distal extremities and being comprised of a flexible elongate tubular member having at least one lumen extending therethrough extending the length thereof, a plurality of longitudinally and radially spaced apart electrodes, expandable means secured to the distal extremity of the flexible elongate tubular member and being movable between a contracted position and an expanded position, means mounting said electrodes on said expandable means whereby when the expandable means is moved to the expanded position in a chamber in the heart, the electrodes are moved into engagement with the wall forming the chamber of the heart in which the expandable means is disposed, means coupled to the expandable means for moving said expandable means between said contracted and expanded positions, leads in contact with the electrodes and extending into the flexible elongate tubular member, electrical means connected to said leads for performing electrical functions with respect to said electrodes, and an ablation catheter having proximal and distal extremities and slidably disposed in said lumen in said catheter probe, said ablation catheter comprising a flexible elongate member having proximal and distal extremities and a centrally disposed lumen extending therethrough, said flexible elongate member of said ablation catheter having at least three additional lumens spaced apart circumferentially about the centrally disposed lumen and extending into the distal extremity, an additional flexible elongate element having a negative coefficient of expansion disposed in each of said three additional lumens in said ablation catheter and having proximal and distal extremities, a common electrical return disposed in the ablation catheter, means interconnecting the distal extremities of the additional flexible elongate elements having a negative coefficient of expansion and said common electrical return, electrical means for supplying electrical energy to said flexible elongate elements having a negative coefficient of expansion to cause bending of the distal extremity of the ablation catheter and means carried by the distal extremity of the ablation catheter for causing ablation in the wall of the heart.
14. In a method for endocardial mapping and ablation of the wall of a heart forming a chamber in the heart and having a passage leading thereto by the utilization of a catheter probe having a plurality of electrodes and an ablation catheter, introducing the catheter probe into the chamber of the heart, performing mapping operations with the catheter probe to ascertain the focus of an arrhythmia in the heart, introducing the ablation catheter so that its distal extremity is disposed within the chamber of the heart while the catheter probe is in the chamber of the heart, manipulating the distal extremity of the ablation catheter while the catheter probe is in the chamber of the heart so that the distal extremity is brought into close proximity to the focus of the arrhythmia and utilizing the ablation catheter for delivering means for causing ablation in the tissue of the wall of the heart to terminate the arrhythmia.
15. A method as in Claim 14 wherein radio frequency energy is delivered to cause the ablation.
16. A method as in Claim 14 wherein laser energy is used to cause the ablation.
17. A method as in Claim 14 wherein a chemical is used to cause the ablation.
18. A method as in Claim 17 wherein a cut is placed into the wall before introduction of the chemical.
19. A method as in Claim 14 by utilization of a computer, utilizing the computer to perform the mapping operation to select an electrode at the plurality of electrodes where an ablation is to be performed, and utilizing the computer to automatically position the distal extremity of the catheter probe in the vicinity of the selected electrode.
20. In an endocardial mapping and ablation system for introduction into a chamber of a heart formed by a wall and having a passage leading thereto, a catheter probe having a distal extremity, a plurality of electrodes, means carried by the distal extremity of the catheter probe for supporting said electrodes in spaced-apart positions so that blood in the chamber of the heart can flow therebetween, an ablation catheter carried by the catheter probe and having a distal extremity movable into the chamber and control means for moving the distal extremity of the ablation catheter independently of movement of the electrodes so that the distal extremity can be brought into close proximity to the wall of the heart between the electrodes and means carried by the distal extremity of the ablation catheter for ablating a portion of the wall of the heart while the distal extremity of the catheter probe is in the chamber of the heart.
21. In a method for endocardial mapping and ablation of the wall of the heart forming a chamber in the heart and having a passage leading thereto by utilization of a catheter probe having a plurality of electrodes and an ablation catheter, introducing the catheter probe into the chamber of the heart, performing mapping operations with the catheter probe by bringing the electrodes of the catheter probe into engagement with the wall of the heart in spaced-apart positions to ascertain the focus of an arrhythmia in the heart, introducing the ablation catheter so that its distal extremities disposed within the chamber of the heart while the catheter probe is in the chamber of the heart, manipulating the distal extremity of the ablation catheter while the catheter probe is in the chamber of the heart so that the distal extremity is brought into close proximity to the focus of the arrhythmia by moving the distal extremity of the ablation catheter between the electrodes and utilizing the ablation catheter for delivering means for causing ablation in the tissue of the wall to terminate the arrhythmia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/894,529 US5324284A (en) | 1992-06-05 | 1992-06-05 | Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and method |
US894,529 | 1992-06-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2097573A1 true CA2097573A1 (en) | 1993-12-06 |
Family
ID=25403201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002097573A Abandoned CA2097573A1 (en) | 1992-06-05 | 1993-06-02 | Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and method |
Country Status (6)
Country | Link |
---|---|
US (3) | US5324284A (en) |
EP (1) | EP0573311B1 (en) |
JP (1) | JPH06142106A (en) |
AT (1) | ATE142114T1 (en) |
CA (1) | CA2097573A1 (en) |
DE (1) | DE69304424T2 (en) |
Families Citing this family (576)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5904680A (en) * | 1992-09-25 | 1999-05-18 | Ep Technologies, Inc. | Multiple electrode support structures having optimal bio-mechanical characteristics |
US6014590A (en) * | 1974-03-04 | 2000-01-11 | Ep Technologies, Inc. | Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions |
US5984939A (en) | 1989-12-05 | 1999-11-16 | Yoon; Inbae | Multifunctional grasping instrument with cutting member and operating channel for use in endoscopic and non-endoscopic procedures |
US5919202A (en) * | 1989-12-05 | 1999-07-06 | Yoon; Inbae | Surgical instrument with jaws and movable internal needle and method for use thereof |
US5893863A (en) * | 1989-12-05 | 1999-04-13 | Yoon; Inbae | Surgical instrument with jaws and movable internal hook member for use thereof |
US5922002A (en) * | 1989-12-05 | 1999-07-13 | Yoon; Inbae | Surgical instrument with jaws and movable internal biopsy device and method for use thereof |
US5922001A (en) * | 1989-12-05 | 1999-07-13 | Yoon; Inbae | Surgical instrument with jaws and a movable internal blade member and method for use thereof |
US5984938A (en) * | 1989-12-05 | 1999-11-16 | Yoon; Inbae | Surgical instrument with jaws and movable internal scissors and method for use thereof |
US5830209A (en) * | 1992-02-05 | 1998-11-03 | Angeion Corporation | Multi-fiber laser catheter |
US5411025A (en) * | 1992-06-30 | 1995-05-02 | Cordis Webster, Inc. | Cardiovascular catheter with laterally stable basket-shaped electrode array |
US5772590A (en) * | 1992-06-30 | 1998-06-30 | Cordis Webster, Inc. | Cardiovascular catheter with laterally stable basket-shaped electrode array with puller wire |
US5782239A (en) | 1992-06-30 | 1998-07-21 | Cordis Webster, Inc. | Unique electrode configurations for cardiovascular electrode catheter with built-in deflection method and central puller wire |
US7189208B1 (en) | 1992-09-23 | 2007-03-13 | Endocardial Solutions, Inc. | Method for measuring heart electrophysiology |
US6240307B1 (en) | 1993-09-23 | 2001-05-29 | Endocardial Solutions, Inc. | Endocardial mapping system |
WO1994006349A1 (en) * | 1992-09-23 | 1994-03-31 | Endocardial Therapeutics, Inc. | Endocardial mapping system |
US7930012B2 (en) * | 1992-09-23 | 2011-04-19 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Chamber location method |
US5566096A (en) * | 1992-11-13 | 1996-10-15 | Quinton Electrophysiology Corporation | Integrated electrical signal switching and amplifying system |
US5676693A (en) * | 1992-11-13 | 1997-10-14 | Scimed Life Systems, Inc. | Electrophysiology device |
US6068653A (en) * | 1992-11-13 | 2000-05-30 | Scimed Life Systems, Inc. | Electrophysiology catheter device |
US6161543A (en) * | 1993-02-22 | 2000-12-19 | Epicor, Inc. | Methods of epicardial ablation for creating a lesion around the pulmonary veins |
US5433198A (en) | 1993-03-11 | 1995-07-18 | Desai; Jawahar M. | Apparatus and method for cardiac ablation |
US5657755A (en) * | 1993-03-11 | 1997-08-19 | Desai; Jawahar M. | Apparatus and method for cardiac ablation |
US6522905B2 (en) | 1993-03-11 | 2003-02-18 | Jawahar M. Desai | Apparatus and method for cardiac ablation |
US5476495A (en) * | 1993-03-16 | 1995-12-19 | Ep Technologies, Inc. | Cardiac mapping and ablation systems |
US6233491B1 (en) | 1993-03-16 | 2001-05-15 | Ep Technologies, Inc. | Cardiac mapping and ablation systems |
US5725525A (en) * | 1993-03-16 | 1998-03-10 | Ep Technologies, Inc. | Multiple electrode support structures with integral hub and spline elements |
US5823189A (en) * | 1993-03-16 | 1998-10-20 | Ep Technologies, Inc. | Multiple electrode support structures with spline elements and over-molded hub |
CA2158453C (en) * | 1993-03-16 | 1999-11-16 | Thomas F. Kordis | Multiple electrode support structures |
US5893847A (en) | 1993-03-16 | 1999-04-13 | Ep Technologies, Inc. | Multiple electrode support structures with slotted hub and hoop spline elements |
IL116699A (en) | 1996-01-08 | 2001-09-13 | Biosense Ltd | Method of constructing cardiac map |
US5409000A (en) * | 1993-09-14 | 1995-04-25 | Cardiac Pathways Corporation | Endocardial mapping and ablation system utilizing separately controlled steerable ablation catheter with ultrasonic imaging capabilities and method |
US5908446A (en) * | 1994-07-07 | 1999-06-01 | Cardiac Pathways Corporation | Catheter assembly, catheter and multi-port introducer for use therewith |
US5400783A (en) * | 1993-10-12 | 1995-03-28 | Cardiac Pathways Corporation | Endocardial mapping apparatus with rotatable arm and method |
US6129724A (en) * | 1993-10-14 | 2000-10-10 | Ep Technologies, Inc. | Systems and methods for forming elongated lesion patterns in body tissue using straight or curvilinear electrode elements |
US5881727A (en) * | 1993-10-14 | 1999-03-16 | Ep Technologies, Inc. | Integrated cardiac mapping and ablation probe |
ES2260758T3 (en) * | 1993-10-14 | 2006-11-01 | Boston Scientific Limited | ELECTRODE ELEMENTS TO FORM INJURY PATTERNS. |
US5582609A (en) * | 1993-10-14 | 1996-12-10 | Ep Technologies, Inc. | Systems and methods for forming large lesions in body tissue using curvilinear electrode elements |
WO1995010322A1 (en) * | 1993-10-15 | 1995-04-20 | Ep Technologies, Inc. | Creating complex lesion patterns in body tissue |
WO1995010320A1 (en) | 1993-10-15 | 1995-04-20 | Ep Technologies, Inc. | Device for lengthening cardiac conduction pathways |
US6146379A (en) * | 1993-10-15 | 2000-11-14 | Ep Technologies, Inc. | Systems and methods for creating curvilinear lesions in body tissue |
US6001093A (en) | 1993-10-15 | 1999-12-14 | Ep Technologies, Inc. | Systems and methods for creating long, thin lesions in body tissue |
US5545193A (en) * | 1993-10-15 | 1996-08-13 | Ep Technologies, Inc. | Helically wound radio-frequency emitting electrodes for creating lesions in body tissue |
US5575810A (en) * | 1993-10-15 | 1996-11-19 | Ep Technologies, Inc. | Composite structures and methods for ablating tissue to form complex lesion patterns in the treatment of cardiac conditions and the like |
US5640955A (en) * | 1995-02-14 | 1997-06-24 | Daig Corporation | Guiding introducers for use in the treatment of accessory pathways around the mitral valve using a retrograde approach |
US5487385A (en) * | 1993-12-03 | 1996-01-30 | Avitall; Boaz | Atrial mapping and ablation catheter system |
US5921924A (en) * | 1993-12-03 | 1999-07-13 | Avitall; Boaz | Mapping and ablation catheter system utilizing multiple control elements |
US5730127A (en) * | 1993-12-03 | 1998-03-24 | Avitall; Boaz | Mapping and ablation catheter system |
US5577509A (en) * | 1994-01-28 | 1996-11-26 | Ep Technologies, Inc. | Systems and methods for examining the electrical characteristics and timing of electrical events in cardiac tissue |
US5485849A (en) * | 1994-01-31 | 1996-01-23 | Ep Technologies, Inc. | System and methods for matching electrical characteristics and propagation velocities in cardiac tissue |
WO1995020348A1 (en) * | 1994-01-28 | 1995-08-03 | Ep Technologies, Inc. | Matching electrical characteristics and propagation velocities to locate ablation sites |
WO1995020344A1 (en) | 1994-01-28 | 1995-08-03 | Ep Technologies, Inc. | System for examining cardiac tissue electrical characteristics |
US5487391A (en) * | 1994-01-28 | 1996-01-30 | Ep Technologies, Inc. | Systems and methods for deriving and displaying the propagation velocities of electrical events in the heart |
US5494042A (en) * | 1994-01-28 | 1996-02-27 | Ep Technologies, Inc. | Systems and methods for deriving electrical characteristics of cardiac tissue for output in iso-characteristic displays |
US6216043B1 (en) | 1994-03-04 | 2001-04-10 | Ep Technologies, Inc. | Asymmetric multiple electrode support structures |
US5598848A (en) * | 1994-03-31 | 1997-02-04 | Ep Technologies, Inc. | Systems and methods for positioning multiple electrode structures in electrical contact with the myocardium |
US5882333A (en) * | 1994-05-13 | 1999-03-16 | Cardima, Inc. | Catheter with deflectable distal section |
NL9400841A (en) * | 1994-05-24 | 1996-01-02 | Industrial Res Bv | Catheter assembly |
US6009877A (en) | 1994-06-24 | 2000-01-04 | Edwards; Stuart D. | Method for treating a sphincter |
US6056744A (en) * | 1994-06-24 | 2000-05-02 | Conway Stuart Medical, Inc. | Sphincter treatment apparatus |
US6405732B1 (en) * | 1994-06-24 | 2002-06-18 | Curon Medical, Inc. | Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors |
US6733495B1 (en) | 1999-09-08 | 2004-05-11 | Curon Medical, Inc. | Systems and methods for monitoring and controlling use of medical devices |
US6676656B2 (en) | 1994-09-09 | 2004-01-13 | Cardiofocus, Inc. | Surgical ablation with radiant energy |
US6423055B1 (en) * | 1999-07-14 | 2002-07-23 | Cardiofocus, Inc. | Phototherapeutic wave guide apparatus |
US6558375B1 (en) | 2000-07-14 | 2003-05-06 | Cardiofocus, Inc. | Cardiac ablation instrument |
US8025661B2 (en) | 1994-09-09 | 2011-09-27 | Cardiofocus, Inc. | Coaxial catheter instruments for ablation with radiant energy |
US6579285B2 (en) | 1994-09-09 | 2003-06-17 | Cardiofocus, Inc. | Photoablation with infrared radiation |
US6464700B1 (en) | 1994-10-07 | 2002-10-15 | Scimed Life Systems, Inc. | Loop structures for positioning a diagnostic or therapeutic element on the epicardium or other organ surface |
US6071274A (en) * | 1996-12-19 | 2000-06-06 | Ep Technologies, Inc. | Loop structures for supporting multiple electrode elements |
US7175619B2 (en) * | 1994-10-07 | 2007-02-13 | Boston Scientific Scimed, Inc. | Loop structures for positioning a diagnostic or therapeutic element on the epicardium or other organ surface |
US5885278A (en) | 1994-10-07 | 1999-03-23 | E.P. Technologies, Inc. | Structures for deploying movable electrode elements |
US5836947A (en) * | 1994-10-07 | 1998-11-17 | Ep Technologies, Inc. | Flexible structures having movable splines for supporting electrode elements |
US5722402A (en) * | 1994-10-11 | 1998-03-03 | Ep Technologies, Inc. | Systems and methods for guiding movable electrode elements within multiple-electrode structures |
US5630809A (en) * | 1994-12-19 | 1997-05-20 | Connor; Christopher S. | Intraocular slit illuminator and method therefor |
IT1278369B1 (en) * | 1995-02-14 | 1997-11-20 | Sorin Biomedica Cardio Spa | CATHETER, PARTICULARLY FOR THE TREATMENT OF HEART ARRHYTHMIA. |
US5722416A (en) * | 1995-02-17 | 1998-03-03 | Ep Technologies, Inc. | Systems and methods for analyzing biopotential morphologies in heart tissue to locate potential ablation sites |
US5595183A (en) * | 1995-02-17 | 1997-01-21 | Ep Technologies, Inc. | Systems and methods for examining heart tissue employing multiple electrode structures and roving electrodes |
US5711305A (en) * | 1995-02-17 | 1998-01-27 | Ep Technologies, Inc. | Systems and methods for acquiring endocardially or epicardially paced electrocardiograms |
US5605157A (en) * | 1995-02-17 | 1997-02-25 | Ep Technologies, Inc. | Systems and methods for filtering signals derived from biological events |
US5630425A (en) * | 1995-02-17 | 1997-05-20 | Ep Technologies, Inc. | Systems and methods for adaptive filtering artifacts from composite signals |
US5601088A (en) * | 1995-02-17 | 1997-02-11 | Ep Technologies, Inc. | Systems and methods for filtering artifacts from composite signals |
US6101409A (en) * | 1995-02-17 | 2000-08-08 | Ep Technologies, Inc. | Systems and methods for analyzing biopotential morphologies in body tissue |
US5609157A (en) * | 1995-02-17 | 1997-03-11 | Ep Technologies, Inc. | Systems and methods for analyzing biopotential morphologies in body tissue using iterative techniques |
JP3681126B2 (en) * | 1995-02-17 | 2005-08-10 | ボストン サイエンティフィック リミテッド | System for time-series measurement of biological events |
US5897553A (en) | 1995-11-02 | 1999-04-27 | Medtronic, Inc. | Ball point fluid-assisted electrocautery device |
US6409722B1 (en) | 1998-07-07 | 2002-06-25 | Medtronic, Inc. | Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue |
CA2225705A1 (en) * | 1995-04-20 | 1996-10-24 | Jawahar M. Desai | Apparatus and method for cardiac ablation |
US6002956A (en) * | 1995-05-23 | 1999-12-14 | Cardima, Inc. | Method of treating using an over-the-wire EP catheter |
US5782760A (en) * | 1995-05-23 | 1998-07-21 | Cardima, Inc. | Over-the-wire EP catheter |
US5895355A (en) * | 1995-05-23 | 1999-04-20 | Cardima, Inc. | Over-the-wire EP catheter |
US6132438A (en) * | 1995-06-07 | 2000-10-17 | Ep Technologies, Inc. | Devices for installing stasis reducing means in body tissue |
US6224584B1 (en) | 1997-01-14 | 2001-05-01 | Eclipse Surgical Technologies, Inc. | Therapeutic and diagnostic agent delivery |
US5840059A (en) * | 1995-06-07 | 1998-11-24 | Cardiogenesis Corporation | Therapeutic and diagnostic agent delivery |
US6780180B1 (en) | 1995-06-23 | 2004-08-24 | Gyrus Medical Limited | Electrosurgical instrument |
CA2224975A1 (en) | 1995-06-23 | 1997-01-09 | Gyrus Medical Limited | An electrosurgical instrument |
KR100463935B1 (en) | 1995-06-23 | 2005-05-16 | 자이러스 메디칼 리미티드 | An electrosurgical instrument |
US6015406A (en) | 1996-01-09 | 2000-01-18 | Gyrus Medical Limited | Electrosurgical instrument |
US6293942B1 (en) | 1995-06-23 | 2001-09-25 | Gyrus Medical Limited | Electrosurgical generator method |
US6023638A (en) * | 1995-07-28 | 2000-02-08 | Scimed Life Systems, Inc. | System and method for conducting electrophysiological testing using high-voltage energy pulses to stun tissue |
WO1997004702A1 (en) * | 1995-07-28 | 1997-02-13 | Ep Technologies, Inc. | Systems and methods for conducting electrophysiological testing using high-voltage energy pulses to stun heart tissue |
US6156031A (en) * | 1995-08-09 | 2000-12-05 | Eclipse Surgical Technologies | Transmyocardial revascularization using radiofrequency energy |
US6267757B1 (en) | 1995-08-09 | 2001-07-31 | Eclipse Surgical Technologies, Inc. | Revascularization with RF ablation |
WO1997017893A1 (en) * | 1995-11-13 | 1997-05-22 | Heart Rhythm Technologies, Inc. | System and method for analyzing electrogram waveforms |
US6013076A (en) | 1996-01-09 | 2000-01-11 | Gyrus Medical Limited | Electrosurgical instrument |
US6090106A (en) | 1996-01-09 | 2000-07-18 | Gyrus Medical Limited | Electrosurgical instrument |
US5885258A (en) * | 1996-02-23 | 1999-03-23 | Memory Medical Systems, Inc. | Medical instrument with slotted memory metal tube |
US5755760A (en) * | 1996-03-11 | 1998-05-26 | Medtronic, Inc. | Deflectable catheter |
US5779699A (en) * | 1996-03-29 | 1998-07-14 | Medtronic, Inc. | Slip resistant field focusing ablation catheter electrode |
US5725521A (en) * | 1996-03-29 | 1998-03-10 | Eclipse Surgical Technologies, Inc. | Depth stop apparatus and method for laser-assisted transmyocardial revascularization and other surgical applications |
US5807324A (en) * | 1996-04-01 | 1998-09-15 | Procath Corporation | Steerable catheter |
NL1003024C2 (en) | 1996-05-03 | 1997-11-06 | Tjong Hauw Sie | Stimulus conduction blocking instrument. |
US5800428A (en) * | 1996-05-16 | 1998-09-01 | Angeion Corporation | Linear catheter ablation system |
GB9612993D0 (en) | 1996-06-20 | 1996-08-21 | Gyrus Medical Ltd | Electrosurgical instrument |
GB2314274A (en) | 1996-06-20 | 1997-12-24 | Gyrus Medical Ltd | Electrode construction for an electrosurgical instrument |
US6565561B1 (en) | 1996-06-20 | 2003-05-20 | Cyrus Medical Limited | Electrosurgical instrument |
US5755664A (en) * | 1996-07-11 | 1998-05-26 | Arch Development Corporation | Wavefront direction mapping catheter system |
US6482224B1 (en) | 1996-08-22 | 2002-11-19 | The Trustees Of Columbia University In The City Of New York | Endovascular flexible stapling device |
US8353908B2 (en) | 1996-09-20 | 2013-01-15 | Novasys Medical, Inc. | Treatment of tissue in sphincters, sinuses, and orifices |
US6464697B1 (en) | 1998-02-19 | 2002-10-15 | Curon Medical, Inc. | Stomach and adjoining tissue regions in the esophagus |
US5820568A (en) * | 1996-10-15 | 1998-10-13 | Cardiac Pathways Corporation | Apparatus and method for aiding in the positioning of a catheter |
US5810803A (en) * | 1996-10-16 | 1998-09-22 | Fidus Medical Technology Corporation | Conformal positioning assembly for microwave ablation catheter |
US6840936B2 (en) | 1996-10-22 | 2005-01-11 | Epicor Medical, Inc. | Methods and devices for ablation |
US6805128B1 (en) | 1996-10-22 | 2004-10-19 | Epicor Medical, Inc. | Apparatus and method for ablating tissue |
US6237605B1 (en) * | 1996-10-22 | 2001-05-29 | Epicor, Inc. | Methods of epicardial ablation |
US6311692B1 (en) | 1996-10-22 | 2001-11-06 | Epicor, Inc. | Apparatus and method for diagnosis and therapy of electrophysiological disease |
US20040260278A1 (en) * | 1996-10-22 | 2004-12-23 | Anderson Scott C. | Apparatus and method for ablating tissue |
US7052493B2 (en) * | 1996-10-22 | 2006-05-30 | Epicor Medical, Inc. | Methods and devices for ablation |
US6719755B2 (en) * | 1996-10-22 | 2004-04-13 | Epicor Medical, Inc. | Methods and devices for ablation |
US5893848A (en) * | 1996-10-24 | 1999-04-13 | Plc Medical Systems, Inc. | Gauging system for monitoring channel depth in percutaneous endocardial revascularization |
US5722403A (en) * | 1996-10-28 | 1998-03-03 | Ep Technologies, Inc. | Systems and methods using a porous electrode for ablating and visualizing interior tissue regions |
US5848969A (en) * | 1996-10-28 | 1998-12-15 | Ep Technologies, Inc. | Systems and methods for visualizing interior tissue regions using expandable imaging structures |
US6059726A (en) * | 1996-11-08 | 2000-05-09 | The Regents Of The University Of California | Method for locating the atrio-ventricular (AV) junction of the heart and injecting active substances therein |
EP0842640A1 (en) * | 1996-11-13 | 1998-05-20 | Sulzer Osypka GmbH | Heart catheter with electrode positioned on a distensible element |
US5931848A (en) * | 1996-12-02 | 1999-08-03 | Angiotrax, Inc. | Methods for transluminally performing surgery |
US6102926A (en) * | 1996-12-02 | 2000-08-15 | Angiotrax, Inc. | Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and methods of use |
US6165188A (en) * | 1996-12-02 | 2000-12-26 | Angiotrax, Inc. | Apparatus for percutaneously performing myocardial revascularization having controlled cutting depth and methods of use |
US6120520A (en) | 1997-05-27 | 2000-09-19 | Angiotrax, Inc. | Apparatus and methods for stimulating revascularization and/or tissue growth |
US6051008A (en) | 1996-12-02 | 2000-04-18 | Angiotrax, Inc. | Apparatus having stabilization members for percutaneously performing surgery and methods of use |
US6076012A (en) | 1996-12-19 | 2000-06-13 | Ep Technologies, Inc. | Structures for supporting porous electrode elements |
US6203525B1 (en) | 1996-12-19 | 2001-03-20 | Ep Technologies, Inc. | Catheterdistal assembly with pull wires |
US6332880B1 (en) | 1996-12-19 | 2001-12-25 | Ep Technologies, Inc. | Loop structures for supporting multiple electrode elements |
US6071279A (en) * | 1996-12-19 | 2000-06-06 | Ep Technologies, Inc. | Branched structures for supporting multiple electrode elements |
US6048329A (en) * | 1996-12-19 | 2000-04-11 | Ep Technologies, Inc. | Catheter distal assembly with pull wires |
GB9626512D0 (en) | 1996-12-20 | 1997-02-05 | Gyrus Medical Ltd | An improved electrosurgical generator and system |
US5919188A (en) * | 1997-02-04 | 1999-07-06 | Medtronic, Inc. | Linear ablation catheter |
US5788636A (en) * | 1997-02-25 | 1998-08-04 | Acuson Corporation | Method and system for forming an ultrasound image of a tissue while simultaneously ablating the tissue |
US6411852B1 (en) | 1997-04-07 | 2002-06-25 | Broncus Technologies, Inc. | Modification of airways by application of energy |
US6488673B1 (en) * | 1997-04-07 | 2002-12-03 | Broncus Technologies, Inc. | Method of increasing gas exchange of a lung |
US6283988B1 (en) | 1997-04-07 | 2001-09-04 | Broncus Technologies, Inc. | Bronchial stenter having expandable electrodes |
US6200333B1 (en) | 1997-04-07 | 2001-03-13 | Broncus Technologies, Inc. | Bronchial stenter |
US5972026A (en) | 1997-04-07 | 1999-10-26 | Broncus Technologies, Inc. | Bronchial stenter having diametrically adjustable electrodes |
US7027869B2 (en) | 1998-01-07 | 2006-04-11 | Asthmatx, Inc. | Method for treating an asthma attack |
US6634363B1 (en) | 1997-04-07 | 2003-10-21 | Broncus Technologies, Inc. | Methods of treating lungs having reversible obstructive pulmonary disease |
US6273907B1 (en) | 1997-04-07 | 2001-08-14 | Broncus Technologies, Inc. | Bronchial stenter |
US7992572B2 (en) | 1998-06-10 | 2011-08-09 | Asthmatx, Inc. | Methods of evaluating individuals having reversible obstructive pulmonary disease |
US6050267A (en) * | 1997-04-28 | 2000-04-18 | American Cardiac Ablation Co. Inc. | Catheter positioning system |
US5944022A (en) * | 1997-04-28 | 1999-08-31 | American Cardiac Ablation Co. Inc. | Catheter positioning system |
US6012457A (en) | 1997-07-08 | 2000-01-11 | The Regents Of The University Of California | Device and method for forming a circumferential conduction block in a pulmonary vein |
US6024740A (en) | 1997-07-08 | 2000-02-15 | The Regents Of The University Of California | Circumferential ablation device assembly |
US5971983A (en) | 1997-05-09 | 1999-10-26 | The Regents Of The University Of California | Tissue ablation device and method of use |
US5876399A (en) * | 1997-05-28 | 1999-03-02 | Irvine Biomedical, Inc. | Catheter system and methods thereof |
US5904698A (en) * | 1997-06-10 | 1999-05-18 | Applied Medical Resources Corporation | Surgical shaving device for use within body conduits |
US6869431B2 (en) | 1997-07-08 | 2005-03-22 | Atrionix, Inc. | Medical device with sensor cooperating with expandable member |
US6164283A (en) * | 1997-07-08 | 2000-12-26 | The Regents Of The University Of California | Device and method for forming a circumferential conduction block in a pulmonary vein |
US6514249B1 (en) | 1997-07-08 | 2003-02-04 | Atrionix, Inc. | Positioning system and method for orienting an ablation element within a pulmonary vein ostium |
US6117101A (en) | 1997-07-08 | 2000-09-12 | The Regents Of The University Of California | Circumferential ablation device assembly |
US6500174B1 (en) | 1997-07-08 | 2002-12-31 | Atrionix, Inc. | Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member |
US6652515B1 (en) | 1997-07-08 | 2003-11-25 | Atrionix, Inc. | Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall |
US6245064B1 (en) | 1997-07-08 | 2001-06-12 | Atrionix, Inc. | Circumferential ablation device assembly |
US6096037A (en) | 1997-07-29 | 2000-08-01 | Medtronic, Inc. | Tissue sealing electrosurgery device and methods of sealing tissue |
US6014579A (en) * | 1997-07-21 | 2000-01-11 | Cardiac Pathways Corp. | Endocardial mapping catheter with movable electrode |
US6490474B1 (en) | 1997-08-01 | 2002-12-03 | Cardiac Pathways Corporation | System and method for electrode localization using ultrasound |
US5891138A (en) * | 1997-08-11 | 1999-04-06 | Irvine Biomedical, Inc. | Catheter system having parallel electrodes |
US9023031B2 (en) | 1997-08-13 | 2015-05-05 | Verathon Inc. | Noninvasive devices, methods, and systems for modifying tissues |
US6610055B1 (en) | 1997-10-10 | 2003-08-26 | Scimed Life Systems, Inc. | Surgical method for positioning a diagnostic or therapeutic element on the epicardium or other organ surface |
US8709007B2 (en) | 1997-10-15 | 2014-04-29 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Devices and methods for ablating cardiac tissue |
US6063082A (en) * | 1997-11-04 | 2000-05-16 | Scimed Life Systems, Inc. | Percutaneous myocardial revascularization basket delivery system and radiofrequency therapeutic device |
GB2331365B (en) * | 1997-11-15 | 2002-03-13 | Roke Manor Research | Catheter tracking system |
US6120476A (en) * | 1997-12-01 | 2000-09-19 | Cordis Webster, Inc. | Irrigated tip catheter |
US7921855B2 (en) | 1998-01-07 | 2011-04-12 | Asthmatx, Inc. | Method for treating an asthma attack |
US6440128B1 (en) | 1998-01-14 | 2002-08-27 | Curon Medical, Inc. | Actively cooled electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions |
AU2224499A (en) | 1998-01-14 | 1999-08-02 | Curon Medical, Inc. | Electrosurgical apparatus for treating gastroesophageal reflux disease (gerd) and method |
AU2114299A (en) * | 1998-01-14 | 1999-08-02 | Conway-Stuart Medical, Inc. | Electrosurgical device for sphincter treatment |
AU2317899A (en) * | 1998-01-14 | 1999-08-02 | Conway-Stuart Medical, Inc. | Gerd treatment apparatus and method |
US6258087B1 (en) | 1998-02-19 | 2001-07-10 | Curon Medical, Inc. | Expandable electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions |
US6423058B1 (en) | 1998-02-19 | 2002-07-23 | Curon Medical, Inc. | Assemblies to visualize and treat sphincters and adjoining tissue regions |
US6358245B1 (en) | 1998-02-19 | 2002-03-19 | Curon Medical, Inc. | Graphical user interface for association with an electrode structure deployed in contact with a tissue region |
US6325798B1 (en) | 1998-02-19 | 2001-12-04 | Curon Medical, Inc. | Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions |
US6645201B1 (en) * | 1998-02-19 | 2003-11-11 | Curon Medical, Inc. | Systems and methods for treating dysfunctions in the intestines and rectum |
US6402744B2 (en) | 1998-02-19 | 2002-06-11 | Curon Medical, Inc. | Systems and methods for forming composite lesions to treat dysfunction in sphincters and adjoining tissue regions |
US6790207B2 (en) | 1998-06-04 | 2004-09-14 | Curon Medical, Inc. | Systems and methods for applying a selected treatment agent into contact with tissue to treat disorders of the gastrointestinal tract |
CA2319517A1 (en) | 1998-02-19 | 1999-08-26 | Curon Medical, Inc. | Electrosurgical sphincter treatment apparatus |
US6273886B1 (en) | 1998-02-19 | 2001-08-14 | Curon Medical, Inc. | Integrated tissue heating and cooling apparatus |
US8906010B2 (en) | 1998-02-19 | 2014-12-09 | Mederi Therapeutics, Inc. | Graphical user interface for association with an electrode structure deployed in contact with a tissue region |
US7165551B2 (en) | 1998-02-19 | 2007-01-23 | Curon Medical, Inc. | Apparatus to detect and treat aberrant myoelectric activity |
US6355031B1 (en) | 1998-02-19 | 2002-03-12 | Curon Medical, Inc. | Control systems for multiple electrode arrays to create lesions in tissue regions at or near a sphincter |
EP1056405A1 (en) | 1998-02-27 | 2000-12-06 | Curon Medical, Inc. | Apparatus to electrosurgically treat esophageal sphincters |
US20030135206A1 (en) | 1998-02-27 | 2003-07-17 | Curon Medical, Inc. | Method for treating a sphincter |
WO1999044522A1 (en) * | 1998-03-06 | 1999-09-10 | Conway-Stuart Medical, Inc. | Apparatus to electrosurgically treat esophageal sphincters |
GB9807303D0 (en) | 1998-04-03 | 1998-06-03 | Gyrus Medical Ltd | An electrode assembly for an electrosurgical instrument |
US6135996A (en) * | 1998-04-17 | 2000-10-24 | Baxter International, Inc. | Controlled advancement lasing device |
WO1999053854A2 (en) * | 1998-04-22 | 1999-10-28 | Cardiosynopsis, Inc. | Method and apparatus for treating an aneurysm |
WO1999055245A1 (en) * | 1998-04-30 | 1999-11-04 | Edwards Stuart D | Electrosurgical sphincter treatment apparatus |
US6652569B1 (en) | 1998-05-08 | 2003-11-25 | Biu Biomedical Innovations (Urology) Inc. | Stent placement and removal |
US6258098B1 (en) | 1998-05-08 | 2001-07-10 | William N. Taylor | Stent placement and removal system |
US6527767B2 (en) * | 1998-05-20 | 2003-03-04 | New England Medical Center | Cardiac ablation system and method for treatment of cardiac arrhythmias and transmyocardial revascularization |
US6428537B1 (en) | 1998-05-22 | 2002-08-06 | Scimed Life Systems, Inc. | Electrophysiological treatment methods and apparatus employing high voltage pulse to render tissue temporarily unresponsive |
US6107699A (en) * | 1998-05-22 | 2000-08-22 | Scimed Life Systems, Inc. | Power supply for use in electrophysiological apparatus employing high-voltage pulses to render tissue temporarily unresponsive |
US6802841B2 (en) * | 1998-06-04 | 2004-10-12 | Curon Medical, Inc. | Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction |
US20110071468A1 (en) * | 1998-06-04 | 2011-03-24 | Mederi Therapeutics, Inc. | Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction |
US8181656B2 (en) | 1998-06-10 | 2012-05-22 | Asthmatx, Inc. | Methods for treating airways |
US7198635B2 (en) | 2000-10-17 | 2007-04-03 | Asthmatx, Inc. | Modification of airways by application of energy |
US7670297B1 (en) | 1998-06-30 | 2010-03-02 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Chamber mapping system |
US7263397B2 (en) | 1998-06-30 | 2007-08-28 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Method and apparatus for catheter navigation and location and mapping in the heart |
US7806829B2 (en) * | 1998-06-30 | 2010-10-05 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System and method for navigating an ultrasound catheter to image a beating heart |
US7187973B2 (en) * | 1998-06-30 | 2007-03-06 | Endocardial Solutions, Inc. | Congestive heart failure pacing optimization method and device |
US6706039B2 (en) | 1998-07-07 | 2004-03-16 | Medtronic, Inc. | Method and apparatus for creating a bi-polar virtual electrode used for the ablation of tissue |
US6537248B2 (en) * | 1998-07-07 | 2003-03-25 | Medtronic, Inc. | Helical needle apparatus for creating a virtual electrode used for the ablation of tissue |
US6296639B1 (en) * | 1999-02-12 | 2001-10-02 | Novacept | Apparatuses and methods for interstitial tissue removal |
US6226542B1 (en) | 1998-07-24 | 2001-05-01 | Biosense, Inc. | Three-dimensional reconstruction of intrabody organs |
US6301496B1 (en) | 1998-07-24 | 2001-10-09 | Biosense, Inc. | Vector mapping of three-dimensionally reconstructed intrabody organs and method of display |
US8308719B2 (en) | 1998-09-21 | 2012-11-13 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Apparatus and method for ablating tissue |
AU1442500A (en) | 1998-10-05 | 2000-04-26 | Scimed Life Systems, Inc. | Large area thermal ablation |
US6241665B1 (en) | 1998-10-21 | 2001-06-05 | Plc Medical System, Inc. | Percutaneous mapping system |
US6607502B1 (en) | 1998-11-25 | 2003-08-19 | Atrionix, Inc. | Apparatus and method incorporating an ultrasound transducer onto a delivery member |
US6556695B1 (en) | 1999-02-05 | 2003-04-29 | Mayo Foundation For Medical Education And Research | Method for producing high resolution real-time images, of structure and function during medical procedures |
US6217528B1 (en) | 1999-02-11 | 2001-04-17 | Scimed Life Systems, Inc. | Loop structure having improved tissue contact capability |
US6325797B1 (en) * | 1999-04-05 | 2001-12-04 | Medtronic, Inc. | Ablation catheter and method for isolating a pulmonary vein |
US6702811B2 (en) | 1999-04-05 | 2004-03-09 | Medtronic, Inc. | Ablation catheter assembly with radially decreasing helix and method of use |
US8285393B2 (en) * | 1999-04-16 | 2012-10-09 | Laufer Michael D | Device for shaping infarcted heart tissue and method of using the device |
AU4696100A (en) | 1999-05-04 | 2000-11-17 | Curon Medical, Inc. | Electrodes for creating lesions in tissue regions at or near a sphincter |
US6758830B1 (en) | 1999-05-11 | 2004-07-06 | Atrionix, Inc. | Catheter positioning system |
EP2289448B1 (en) | 1999-05-11 | 2013-03-13 | Atrionix, Inc. | Tissue ablation system including a balloon anchor wire |
US8540704B2 (en) | 1999-07-14 | 2013-09-24 | Cardiofocus, Inc. | Guided cardiac ablation catheters |
US8900219B2 (en) | 1999-07-14 | 2014-12-02 | Cardiofocus, Inc. | System and method for visualizing tissue during ablation procedures |
US7935108B2 (en) | 1999-07-14 | 2011-05-03 | Cardiofocus, Inc. | Deflectable sheath catheters |
US9033961B2 (en) | 1999-07-14 | 2015-05-19 | Cardiofocus, Inc. | Cardiac ablation catheters for forming overlapping lesions |
EP1207788A4 (en) * | 1999-07-19 | 2009-12-09 | St Jude Medical Atrial Fibrill | Apparatus and method for ablating tissue |
WO2001008575A2 (en) * | 1999-07-30 | 2001-02-08 | Cardiofocus, Inc. | Optical fiber basket device for cardiac photoablation |
US20040147911A1 (en) * | 1999-08-25 | 2004-07-29 | Cardiofocus, Inc. | Surgical ablation instruments for forming an encircling lesion |
US20040167503A1 (en) * | 1999-08-25 | 2004-08-26 | Cardiofocus, Inc. | Malleable surgical ablation instruments |
US6332881B1 (en) | 1999-09-01 | 2001-12-25 | Cardima, Inc. | Surgical ablation tool |
CA2384025A1 (en) * | 1999-09-08 | 2001-03-15 | Curon Medical, Inc. | System for controlling a family of treatment devices |
AU7352500A (en) | 1999-09-08 | 2001-04-10 | Curon Medical, Inc. | Systems and methods for monitoring and controlling use of medical devices |
US6315778B1 (en) | 1999-09-10 | 2001-11-13 | C. R. Bard, Inc. | Apparatus for creating a continuous annular lesion |
US6607520B2 (en) * | 1999-09-15 | 2003-08-19 | The General Hospital Corporation | Coiled ablation catheter system |
US6632223B1 (en) * | 2000-03-30 | 2003-10-14 | The General Hospital Corporation | Pulmonary vein ablation stent and method |
AU3885801A (en) | 1999-09-20 | 2001-04-24 | Stereotaxis, Inc. | Magnetically guided myocardial treatment system |
US6385476B1 (en) | 1999-09-21 | 2002-05-07 | Biosense, Inc. | Method and apparatus for intracardially surveying a condition of a chamber of a heart |
US6368285B1 (en) | 1999-09-21 | 2002-04-09 | Biosense, Inc. | Method and apparatus for mapping a chamber of a heart |
US6829497B2 (en) * | 1999-09-21 | 2004-12-07 | Jamil Mogul | Steerable diagnostic catheters |
US6546271B1 (en) | 1999-10-01 | 2003-04-08 | Bioscience, Inc. | Vascular reconstruction |
US6308093B1 (en) | 1999-10-07 | 2001-10-23 | Massachusetts Institute Of Technology | Method and apparatus for guiding ablative therapy of abnormal biological electrical excitation |
US6370412B1 (en) | 1999-10-07 | 2002-04-09 | Massachusetts Institute Of Technology | Method and apparatus for guiding ablative therapy of abnormal biological electrical excitation |
CA2388861C (en) | 1999-11-16 | 2013-09-03 | Robert A. Ganz | System and method of treating abnormal tissue in the human esophagus |
US20060095032A1 (en) | 1999-11-16 | 2006-05-04 | Jerome Jackson | Methods and systems for determining physiologic characteristics for treatment of the esophagus |
US20040215235A1 (en) | 1999-11-16 | 2004-10-28 | Barrx, Inc. | Methods and systems for determining physiologic characteristics for treatment of the esophagus |
US6542781B1 (en) | 1999-11-22 | 2003-04-01 | Scimed Life Systems, Inc. | Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue |
US6529756B1 (en) * | 1999-11-22 | 2003-03-04 | Scimed Life Systems, Inc. | Apparatus for mapping and coagulating soft tissue in or around body orifices |
US6613046B1 (en) | 1999-11-22 | 2003-09-02 | Scimed Life Systems, Inc. | Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue |
US6645199B1 (en) * | 1999-11-22 | 2003-11-11 | Scimed Life Systems, Inc. | Loop structures for supporting diagnostic and therapeutic elements contact with body tissue and expandable push devices for use with same |
US6547776B1 (en) | 2000-01-03 | 2003-04-15 | Curon Medical, Inc. | Systems and methods for treating tissue in the crura |
US7706882B2 (en) | 2000-01-19 | 2010-04-27 | Medtronic, Inc. | Methods of using high intensity focused ultrasound to form an ablated tissue area |
US8241274B2 (en) | 2000-01-19 | 2012-08-14 | Medtronic, Inc. | Method for guiding a medical device |
US8221402B2 (en) | 2000-01-19 | 2012-07-17 | Medtronic, Inc. | Method for guiding a medical device |
US6692450B1 (en) | 2000-01-19 | 2004-02-17 | Medtronic Xomed, Inc. | Focused ultrasound ablation devices having selectively actuatable ultrasound emitting elements and methods of using the same |
US8048070B2 (en) | 2000-03-06 | 2011-11-01 | Salient Surgical Technologies, Inc. | Fluid-assisted medical devices, systems and methods |
US8251070B2 (en) | 2000-03-27 | 2012-08-28 | Asthmatx, Inc. | Methods for treating airways |
US8888688B2 (en) | 2000-04-03 | 2014-11-18 | Intuitive Surgical Operations, Inc. | Connector device for a controllable instrument |
US8517923B2 (en) * | 2000-04-03 | 2013-08-27 | Intuitive Surgical Operations, Inc. | Apparatus and methods for facilitating treatment of tissue via improved delivery of energy based and non-energy based modalities |
US6488680B1 (en) | 2000-04-27 | 2002-12-03 | Medtronic, Inc. | Variable length electrodes for delivery of irrigated ablation |
US6514250B1 (en) | 2000-04-27 | 2003-02-04 | Medtronic, Inc. | Suction stabilized epicardial ablation devices |
WO2001082812A1 (en) | 2000-04-27 | 2001-11-08 | Medtronic, Inc. | Vibration sensitive ablation apparatus and method |
US6837886B2 (en) | 2000-05-03 | 2005-01-04 | C.R. Bard, Inc. | Apparatus and methods for mapping and ablation in electrophysiology procedures |
AU6321301A (en) | 2000-05-16 | 2001-11-26 | Atrionix Inc | Apparatus and method incorporating an ultrasound transducer onto a delivery member |
US8845632B2 (en) | 2000-05-18 | 2014-09-30 | Mederi Therapeutics, Inc. | Graphical user interface for monitoring and controlling use of medical devices |
ATE290827T1 (en) | 2000-06-13 | 2005-04-15 | Atrionix Inc | SURGICAL ABLATION PROBE FOR FORMING AN ANNUAL LESION |
US6547784B1 (en) * | 2000-06-23 | 2003-04-15 | Ethicon, Inc. | System and method for placement of a surgical instrument in a body cavity |
US6511478B1 (en) * | 2000-06-30 | 2003-01-28 | Scimed Life Systems, Inc. | Medical probe with reduced number of temperature sensor wires |
AU2001273421A1 (en) * | 2000-07-13 | 2002-01-30 | Bioheart, Inc. | Deployment system for myocardial cellular material |
US6650927B1 (en) | 2000-08-18 | 2003-11-18 | Biosense, Inc. | Rendering of diagnostic imaging data on a three-dimensional map |
US6633773B1 (en) | 2000-09-29 | 2003-10-14 | Biosene, Inc. | Area of interest reconstruction for surface of an organ using location data |
US7306591B2 (en) | 2000-10-02 | 2007-12-11 | Novasys Medical, Inc. | Apparatus and methods for treating female urinary incontinence |
US6640120B1 (en) * | 2000-10-05 | 2003-10-28 | Scimed Life Systems, Inc. | Probe assembly for mapping and ablating pulmonary vein tissue and method of using same |
US6926669B1 (en) | 2000-10-10 | 2005-08-09 | Medtronic, Inc. | Heart wall ablation/mapping catheter and method |
US7104987B2 (en) | 2000-10-17 | 2006-09-12 | Asthmatx, Inc. | Control system and process for application of energy to airway walls and other mediums |
US6916306B1 (en) * | 2000-11-10 | 2005-07-12 | Boston Scientific Scimed, Inc. | Steerable loop structures for supporting diagnostic and therapeutic elements in contact with body tissue |
US7785323B2 (en) * | 2000-12-04 | 2010-08-31 | Boston Scientific Scimed, Inc. | Loop structure including inflatable therapeutic device |
US7740623B2 (en) | 2001-01-13 | 2010-06-22 | Medtronic, Inc. | Devices and methods for interstitial injection of biologic agents into tissue |
US20040138621A1 (en) | 2003-01-14 | 2004-07-15 | Jahns Scott E. | Devices and methods for interstitial injection of biologic agents into tissue |
DE10105592A1 (en) | 2001-02-06 | 2002-08-08 | Achim Goepferich | Placeholder for drug release in the frontal sinus |
US8214015B2 (en) * | 2001-02-06 | 2012-07-03 | Medtronic Vascular, Inc. | In vivo localization and tracking of tissue penetrating catheters using magnetic resonance imaging |
US6807968B2 (en) | 2001-04-26 | 2004-10-26 | Medtronic, Inc. | Method and system for treatment of atrial tachyarrhythmias |
US6663627B2 (en) | 2001-04-26 | 2003-12-16 | Medtronic, Inc. | Ablation system and method of use |
US7250048B2 (en) | 2001-04-26 | 2007-07-31 | Medtronic, Inc. | Ablation system and method of use |
US6648883B2 (en) | 2001-04-26 | 2003-11-18 | Medtronic, Inc. | Ablation system and method of use |
US6699240B2 (en) | 2001-04-26 | 2004-03-02 | Medtronic, Inc. | Method and apparatus for tissue ablation |
US7959626B2 (en) | 2001-04-26 | 2011-06-14 | Medtronic, Inc. | Transmural ablation systems and methods |
US7255695B2 (en) * | 2001-04-27 | 2007-08-14 | C.R. Bard, Inc. | Systems and methods for three-dimensional mapping of electrical activity |
US7727229B2 (en) * | 2001-05-01 | 2010-06-01 | C.R. Bard, Inc. | Method and apparatus for altering conduction properties in the heart and in adjacent vessels |
US20030040676A1 (en) * | 2001-05-03 | 2003-02-27 | Prentice John A. | Method and apparatus for determining spatial relation of multiple implantable electrodes |
US20040243118A1 (en) * | 2001-06-01 | 2004-12-02 | Ayers Gregory M. | Device and method for positioning a catheter tip for creating a cryogenic lesion |
EP1435867B1 (en) | 2001-09-05 | 2010-11-17 | Salient Surgical Technologies, Inc. | Fluid-assisted medical devices and systems |
FR2831743B1 (en) * | 2001-10-25 | 2004-01-30 | Cit Alcatel | IS-IS FAULT TOLERANT ROUTING SYSTEM AND CORRESPONDING METHOD |
US7785324B2 (en) * | 2005-02-25 | 2010-08-31 | Endoscopic Technologies, Inc. (Estech) | Clamp based lesion formation apparatus and methods configured to protect non-target tissue |
US7753908B2 (en) * | 2002-02-19 | 2010-07-13 | Endoscopic Technologies, Inc. (Estech) | Apparatus for securing an electrophysiology probe to a clamp |
US6656175B2 (en) | 2001-12-11 | 2003-12-02 | Medtronic, Inc. | Method and system for treatment of atrial tachyarrhythmias |
US6741878B2 (en) * | 2001-12-14 | 2004-05-25 | Biosense Webster, Inc. | Basket catheter with improved expansion mechanism |
US6827715B2 (en) | 2002-01-25 | 2004-12-07 | Medtronic, Inc. | System and method of performing an electrosurgical procedure |
US7967816B2 (en) | 2002-01-25 | 2011-06-28 | Medtronic, Inc. | Fluid-assisted electrosurgical instrument with shapeable electrode |
US20070293855A1 (en) * | 2002-02-15 | 2007-12-20 | Sliwa John W Jr | Methods and devices for ablation |
US6932816B2 (en) * | 2002-02-19 | 2005-08-23 | Boston Scientific Scimed, Inc. | Apparatus for converting a clamp into an electrophysiology device |
US20030199961A1 (en) * | 2002-04-03 | 2003-10-23 | Bjorklund Vicki L. | Method and apparatus for fixating a pacing lead of an implantable medical device |
US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
US20040106896A1 (en) * | 2002-11-29 | 2004-06-03 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
US6932804B2 (en) | 2003-01-21 | 2005-08-23 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
CN1649641A (en) * | 2002-05-08 | 2005-08-03 | 加利福尼亚大学董事会 | System and method for forming a non-ablative cardiac conduction block |
US7118566B2 (en) | 2002-05-16 | 2006-10-10 | Medtronic, Inc. | Device and method for needle-less interstitial injection of fluid for ablation of cardiac tissue |
US7294143B2 (en) | 2002-05-16 | 2007-11-13 | Medtronic, Inc. | Device and method for ablation of cardiac tissue |
US6960203B2 (en) * | 2002-06-26 | 2005-11-01 | Ethicon, Inc. | Thermal ablation with deployable cage |
US7273478B2 (en) * | 2002-07-10 | 2007-09-25 | Angiodynamics, Inc. | Endovascular treatment device having a fiber tip spacer |
US8317816B2 (en) | 2002-09-30 | 2012-11-27 | Acclarent, Inc. | Balloon catheters and methods for treating paranasal sinuses |
US20050033137A1 (en) * | 2002-10-25 | 2005-02-10 | The Regents Of The University Of Michigan | Ablation catheters and methods for their use |
US20040082947A1 (en) * | 2002-10-25 | 2004-04-29 | The Regents Of The University Of Michigan | Ablation catheters |
US7083620B2 (en) | 2002-10-30 | 2006-08-01 | Medtronic, Inc. | Electrosurgical hemostat |
US7317950B2 (en) * | 2002-11-16 | 2008-01-08 | The Regents Of The University Of California | Cardiac stimulation system with delivery of conductive agent |
US8862204B2 (en) | 2002-11-18 | 2014-10-14 | Mediguide Ltd. | Reducing mechanical stress on conductors and connection points in a position determinable interventional medical device |
US7881769B2 (en) * | 2002-11-18 | 2011-02-01 | Mediguide Ltd. | Method and system for mounting an MPS sensor on a catheter |
US7819866B2 (en) * | 2003-01-21 | 2010-10-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ablation catheter and electrode |
US20040186467A1 (en) * | 2003-03-21 | 2004-09-23 | Swanson David K. | Apparatus for maintaining contact between diagnostic and therapeutic elements and tissue and systems including the same |
US7293562B2 (en) | 2003-03-27 | 2007-11-13 | Cierra, Inc. | Energy based devices and methods for treatment of anatomic tissue defects |
US7165552B2 (en) | 2003-03-27 | 2007-01-23 | Cierra, Inc. | Methods and apparatus for treatment of patent foramen ovale |
US7186251B2 (en) | 2003-03-27 | 2007-03-06 | Cierra, Inc. | Energy based devices and methods for treatment of patent foramen ovale |
CA2519636A1 (en) | 2003-03-27 | 2004-10-14 | Cierra, Inc. | Methods and apparatus for treatment of patent foramen ovale |
US8021362B2 (en) | 2003-03-27 | 2011-09-20 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US7972330B2 (en) | 2003-03-27 | 2011-07-05 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US6939348B2 (en) | 2003-03-27 | 2005-09-06 | Cierra, Inc. | Energy based devices and methods for treatment of patent foramen ovale |
DE602004011608T2 (en) * | 2003-03-28 | 2009-01-29 | C.R. Bard, Inc. | Catheter with braided mesh |
US7497857B2 (en) | 2003-04-29 | 2009-03-03 | Medtronic, Inc. | Endocardial dispersive electrode for use with a monopolar RF ablation pen |
US20040226556A1 (en) | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
US7311701B2 (en) | 2003-06-10 | 2007-12-25 | Cierra, Inc. | Methods and apparatus for non-invasively treating atrial fibrillation using high intensity focused ultrasound |
US7235070B2 (en) * | 2003-07-02 | 2007-06-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ablation fluid manifold for ablation catheter |
US7101362B2 (en) | 2003-07-02 | 2006-09-05 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Steerable and shapable catheter employing fluid force |
US8308708B2 (en) | 2003-07-15 | 2012-11-13 | Abbott Cardiovascular Systems Inc. | Deployment system for myocardial cellular material |
US7155270B2 (en) * | 2003-10-24 | 2006-12-26 | Biosense Webster, Inc. | Catheter with multi-spine mapping assembly |
US7179256B2 (en) * | 2003-10-24 | 2007-02-20 | Biosense Webster, Inc. | Catheter with ablation needle and mapping assembly |
DE10355275B4 (en) * | 2003-11-26 | 2009-03-05 | Siemens Ag | catheter device |
US7608072B2 (en) * | 2003-12-02 | 2009-10-27 | Boston Scientific Scimed, Inc. | Surgical methods and apparatus for maintaining contact between tissue and electrophysiology elements and confirming whether a therapeutic lesion has been formed |
US20050119653A1 (en) * | 2003-12-02 | 2005-06-02 | Swanson David K. | Surgical methods and apparatus for forming lesions in tissue and confirming whether a therapeutic lesion has been formed |
US8052676B2 (en) * | 2003-12-02 | 2011-11-08 | Boston Scientific Scimed, Inc. | Surgical methods and apparatus for stimulating tissue |
US8002770B2 (en) | 2003-12-02 | 2011-08-23 | Endoscopic Technologies, Inc. (Estech) | Clamp based methods and apparatus for forming lesions in tissue and confirming whether a therapeutic lesion has been formed |
US7150745B2 (en) | 2004-01-09 | 2006-12-19 | Barrx Medical, Inc. | Devices and methods for treatment of luminal tissue |
US7371233B2 (en) * | 2004-02-19 | 2008-05-13 | Boston Scientific Scimed, Inc. | Cooled probes and apparatus for maintaining contact between cooled probes and tissue |
US8007495B2 (en) * | 2004-03-31 | 2011-08-30 | Biosense Webster, Inc. | Catheter for circumferential ablation at or near a pulmonary vein |
US8932276B1 (en) | 2004-04-21 | 2015-01-13 | Acclarent, Inc. | Shapeable guide catheters and related methods |
US9554691B2 (en) | 2004-04-21 | 2017-01-31 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US7419497B2 (en) | 2004-04-21 | 2008-09-02 | Acclarent, Inc. | Methods for treating ethmoid disease |
US7410480B2 (en) | 2004-04-21 | 2008-08-12 | Acclarent, Inc. | Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders |
US8747389B2 (en) | 2004-04-21 | 2014-06-10 | Acclarent, Inc. | Systems for treating disorders of the ear, nose and throat |
US9101384B2 (en) | 2004-04-21 | 2015-08-11 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat |
US8702626B1 (en) | 2004-04-21 | 2014-04-22 | Acclarent, Inc. | Guidewires for performing image guided procedures |
US20060004323A1 (en) | 2004-04-21 | 2006-01-05 | Exploramed Nc1, Inc. | Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures |
US7559925B2 (en) | 2006-09-15 | 2009-07-14 | Acclarent Inc. | Methods and devices for facilitating visualization in a surgical environment |
US20060063973A1 (en) | 2004-04-21 | 2006-03-23 | Acclarent, Inc. | Methods and apparatus for treating disorders of the ear, nose and throat |
US7654997B2 (en) | 2004-04-21 | 2010-02-02 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat |
US8894614B2 (en) | 2004-04-21 | 2014-11-25 | Acclarent, Inc. | Devices, systems and methods useable for treating frontal sinusitis |
US20070208252A1 (en) | 2004-04-21 | 2007-09-06 | Acclarent, Inc. | Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses |
US20190314620A1 (en) | 2004-04-21 | 2019-10-17 | Acclarent, Inc. | Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures |
US7361168B2 (en) | 2004-04-21 | 2008-04-22 | Acclarent, Inc. | Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders |
US7803150B2 (en) | 2004-04-21 | 2010-09-28 | Acclarent, Inc. | Devices, systems and methods useable for treating sinusitis |
US10188413B1 (en) | 2004-04-21 | 2019-01-29 | Acclarent, Inc. | Deflectable guide catheters and related methods |
US7720521B2 (en) | 2004-04-21 | 2010-05-18 | Acclarent, Inc. | Methods and devices for performing procedures within the ear, nose, throat and paranasal sinuses |
US9089258B2 (en) | 2004-04-21 | 2015-07-28 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US20070167682A1 (en) | 2004-04-21 | 2007-07-19 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US8146400B2 (en) | 2004-04-21 | 2012-04-03 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US9399121B2 (en) | 2004-04-21 | 2016-07-26 | Acclarent, Inc. | Systems and methods for transnasal dilation of passageways in the ear, nose or throat |
US8764729B2 (en) | 2004-04-21 | 2014-07-01 | Acclarent, Inc. | Frontal sinus spacer |
US8864787B2 (en) | 2004-04-21 | 2014-10-21 | Acclarent, Inc. | Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis |
US9351750B2 (en) | 2004-04-21 | 2016-05-31 | Acclarent, Inc. | Devices and methods for treating maxillary sinus disease |
US7462175B2 (en) | 2004-04-21 | 2008-12-09 | Acclarent, Inc. | Devices, systems and methods for treating disorders of the ear, nose and throat |
US8142427B2 (en) * | 2004-04-23 | 2012-03-27 | Boston Scientific Scimed, Inc. | Invasive ablation probe with non-coring distal tip |
US8333764B2 (en) | 2004-05-12 | 2012-12-18 | Medtronic, Inc. | Device and method for determining tissue thickness and creating cardiac ablation lesions |
ES2308505T3 (en) | 2004-05-14 | 2008-12-01 | Medtronic, Inc. | ULTRASONIC ENERGY USE SYSTEM FOCUSED ON HIGH INTENS IDAD TO FORM A CUTTED FABRIC AREA. |
WO2005112813A1 (en) | 2004-05-17 | 2005-12-01 | C.R. Bard, Inc. | Method and apparatus for mapping and7or ablation of cardiac tissue |
US8945116B2 (en) * | 2004-05-17 | 2015-02-03 | Boston Scientific Scimed, Inc. | Mapping and ablation method for the treatment of ventricular tachycardia |
US20050261571A1 (en) * | 2004-05-21 | 2005-11-24 | Willis Nathaniel P | 3-D ultrasound navigation during radio-frequency ablation |
US9782130B2 (en) | 2004-05-28 | 2017-10-10 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Robotic surgical system |
US10258285B2 (en) | 2004-05-28 | 2019-04-16 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Robotic surgical system and method for automated creation of ablation lesions |
US8528565B2 (en) | 2004-05-28 | 2013-09-10 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Robotic surgical system and method for automated therapy delivery |
US7632265B2 (en) | 2004-05-28 | 2009-12-15 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Radio frequency ablation servo catheter and method |
US10863945B2 (en) | 2004-05-28 | 2020-12-15 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Robotic surgical system with contact sensing feature |
US7974674B2 (en) | 2004-05-28 | 2011-07-05 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Robotic surgical system and method for surface modeling |
US8755864B2 (en) | 2004-05-28 | 2014-06-17 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Robotic surgical system and method for diagnostic data mapping |
WO2005120377A1 (en) | 2004-06-02 | 2005-12-22 | Medtronic, Inc. | Clamping ablation tool |
EP1750608B1 (en) | 2004-06-02 | 2012-10-03 | Medtronic, Inc. | Ablation device with jaws |
EP1750607A2 (en) | 2004-06-02 | 2007-02-14 | Medtronic, Inc. | Loop ablation apparatus and method |
DE602005021096D1 (en) | 2004-06-02 | 2010-06-17 | Medtronic Inc | COMPOUND BIPOLAR ABLATION DEVICE |
US8409219B2 (en) | 2004-06-18 | 2013-04-02 | Medtronic, Inc. | Method and system for placement of electrical lead inside heart |
US8663245B2 (en) | 2004-06-18 | 2014-03-04 | Medtronic, Inc. | Device for occlusion of a left atrial appendage |
US8926635B2 (en) | 2004-06-18 | 2015-01-06 | Medtronic, Inc. | Methods and devices for occlusion of an atrial appendage |
US7367975B2 (en) | 2004-06-21 | 2008-05-06 | Cierra, Inc. | Energy based devices and methods for treatment of anatomic tissue defects |
US7462268B2 (en) * | 2004-08-20 | 2008-12-09 | Allan Mishra | Particle/cell separation device and compositions |
US7549988B2 (en) | 2004-08-30 | 2009-06-23 | Boston Scientific Scimed, Inc. | Hybrid lesion formation apparatus, systems and methods |
US7753906B2 (en) * | 2004-09-14 | 2010-07-13 | Richard Esposito | Catheter having anchoring and stabilizing devices |
US20060089637A1 (en) | 2004-10-14 | 2006-04-27 | Werneth Randell L | Ablation catheter |
US7949407B2 (en) | 2004-11-05 | 2011-05-24 | Asthmatx, Inc. | Energy delivery devices and methods |
WO2006052940A2 (en) | 2004-11-05 | 2006-05-18 | Asthmatx, Inc. | Medical device with procedure improvement features |
US20070093802A1 (en) | 2005-10-21 | 2007-04-26 | Danek Christopher J | Energy delivery devices and methods |
US8617152B2 (en) * | 2004-11-15 | 2013-12-31 | Medtronic Ablation Frontiers Llc | Ablation system with feedback |
US7468062B2 (en) * | 2004-11-24 | 2008-12-23 | Ablation Frontiers, Inc. | Atrial ablation catheter adapted for treatment of septal wall arrhythmogenic foci and method of use |
US7429261B2 (en) * | 2004-11-24 | 2008-09-30 | Ablation Frontiers, Inc. | Atrial ablation catheter and method of use |
US7117030B2 (en) * | 2004-12-02 | 2006-10-03 | The Research Foundation Of State University Of New York | Method and algorithm for spatially identifying sources of cardiac fibrillation |
US7731715B2 (en) * | 2004-12-10 | 2010-06-08 | Edwards Lifesciences Corporation | Ablative treatment of atrial fibrillation via the coronary sinus |
US7727231B2 (en) * | 2005-01-08 | 2010-06-01 | Boston Scientific Scimed, Inc. | Apparatus and methods for forming lesions in tissue and applying stimulation energy to tissue in which lesions are formed |
US7455670B2 (en) * | 2005-01-14 | 2008-11-25 | Co-Repair, Inc. | System and method for the treatment of heart tissue |
US20070156210A1 (en) * | 2005-01-14 | 2007-07-05 | Co-Repair, Inc., A California Corporation | Method for the treatment of heart tissue |
US20070156209A1 (en) * | 2005-01-14 | 2007-07-05 | Co-Repair, Inc. | System for the treatment of heart tissue |
US7892228B2 (en) * | 2005-02-25 | 2011-02-22 | Boston Scientific Scimed, Inc. | Dual mode lesion formation apparatus, systems and methods |
US8109274B2 (en) | 2005-04-11 | 2012-02-07 | Terumo Kabushiki Kaisha | Methods and electrode apparatus to achieve a closure of a layered tissue defect |
US20060253025A1 (en) * | 2005-04-21 | 2006-11-09 | Kaufman Jonathan J | Ultrasonic Bone Assessment Apparatus and Method |
US8932208B2 (en) | 2005-05-26 | 2015-01-13 | Maquet Cardiovascular Llc | Apparatus and methods for performing minimally-invasive surgical procedures |
US8155910B2 (en) | 2005-05-27 | 2012-04-10 | St. Jude Medical, Atrial Fibrillation Divison, Inc. | Robotically controlled catheter and method of its calibration |
US8016822B2 (en) * | 2005-05-28 | 2011-09-13 | Boston Scientific Scimed, Inc. | Fluid injecting devices and methods and apparatus for maintaining contact between fluid injecting devices and tissue |
US8951225B2 (en) | 2005-06-10 | 2015-02-10 | Acclarent, Inc. | Catheters with non-removable guide members useable for treatment of sinusitis |
US8795348B2 (en) * | 2005-06-14 | 2014-08-05 | Boston Scientific Scimed, Inc. | Medical devices and related methods |
US7850685B2 (en) | 2005-06-20 | 2010-12-14 | Medtronic Ablation Frontiers Llc | Ablation catheter |
US7819868B2 (en) | 2005-06-21 | 2010-10-26 | St. Jude Medical, Atrial Fibrilation Division, Inc. | Ablation catheter with fluid distribution structures |
EP1909679B1 (en) | 2005-07-11 | 2013-11-20 | Medtronic Ablation Frontiers LLC | Low power tissue ablation system |
US8945151B2 (en) * | 2005-07-13 | 2015-02-03 | Atricure, Inc. | Surgical clip applicator and apparatus including the same |
WO2007014063A2 (en) * | 2005-07-21 | 2007-02-01 | Vnus Medical Technologies, Inc. | Systems and methods for treating a hollow anatomical structure |
US8657814B2 (en) | 2005-08-22 | 2014-02-25 | Medtronic Ablation Frontiers Llc | User interface for tissue ablation system |
US8114113B2 (en) | 2005-09-23 | 2012-02-14 | Acclarent, Inc. | Multi-conduit balloon catheter |
US7997278B2 (en) | 2005-11-23 | 2011-08-16 | Barrx Medical, Inc. | Precision ablating method |
US8702694B2 (en) | 2005-11-23 | 2014-04-22 | Covidien Lp | Auto-aligning ablating device and method of use |
US7959627B2 (en) | 2005-11-23 | 2011-06-14 | Barrx Medical, Inc. | Precision ablating device |
US8190389B2 (en) | 2006-05-17 | 2012-05-29 | Acclarent, Inc. | Adapter for attaching electromagnetic image guidance components to a medical device |
US20080039746A1 (en) | 2006-05-25 | 2008-02-14 | Medtronic, Inc. | Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions |
US9119633B2 (en) | 2006-06-28 | 2015-09-01 | Kardium Inc. | Apparatus and method for intra-cardiac mapping and ablation |
US10028783B2 (en) | 2006-06-28 | 2018-07-24 | Kardium Inc. | Apparatus and method for intra-cardiac mapping and ablation |
US11389232B2 (en) | 2006-06-28 | 2022-07-19 | Kardium Inc. | Apparatus and method for intra-cardiac mapping and ablation |
US8920411B2 (en) | 2006-06-28 | 2014-12-30 | Kardium Inc. | Apparatus and method for intra-cardiac mapping and ablation |
US9820688B2 (en) | 2006-09-15 | 2017-11-21 | Acclarent, Inc. | Sinus illumination lightwire device |
US7931647B2 (en) | 2006-10-20 | 2011-04-26 | Asthmatx, Inc. | Method of delivering energy to a lung airway using markers |
US20080140069A1 (en) * | 2006-12-07 | 2008-06-12 | Cierra, Inc. | Multi-electrode apparatus for tissue welding and ablation |
US8439687B1 (en) | 2006-12-29 | 2013-05-14 | Acclarent, Inc. | Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices |
US8473030B2 (en) * | 2007-01-12 | 2013-06-25 | Medtronic Vascular, Inc. | Vessel position and configuration imaging apparatus and methods |
US9314298B2 (en) * | 2007-04-17 | 2016-04-19 | St. Jude Medical, Atrial Fibrillation Divisions, Inc. | Vacuum-stabilized ablation system |
US8118757B2 (en) | 2007-04-30 | 2012-02-21 | Acclarent, Inc. | Methods and devices for ostium measurement |
US8641711B2 (en) | 2007-05-04 | 2014-02-04 | Covidien Lp | Method and apparatus for gastrointestinal tract ablation for treatment of obesity |
US8485199B2 (en) | 2007-05-08 | 2013-07-16 | Acclarent, Inc. | Methods and devices for protecting nasal turbinate during surgery |
US8641704B2 (en) | 2007-05-11 | 2014-02-04 | Medtronic Ablation Frontiers Llc | Ablation therapy system and method for treating continuous atrial fibrillation |
US8784338B2 (en) | 2007-06-22 | 2014-07-22 | Covidien Lp | Electrical means to normalize ablational energy transmission to a luminal tissue surface of varying size |
US8251992B2 (en) | 2007-07-06 | 2012-08-28 | Tyco Healthcare Group Lp | Method and apparatus for gastrointestinal tract ablation to achieve loss of persistent and/or recurrent excess body weight following a weight-loss operation |
CN102688092B (en) | 2007-07-06 | 2015-04-22 | 柯惠有限合伙公司 | Ablation in the gastrointestinal tract to achieve hemostasis and eradicate lesions with a propensity for bleeding |
US8235983B2 (en) | 2007-07-12 | 2012-08-07 | Asthmatx, Inc. | Systems and methods for delivering energy to passageways in a patient |
US8273012B2 (en) | 2007-07-30 | 2012-09-25 | Tyco Healthcare Group, Lp | Cleaning device and methods |
US8646460B2 (en) | 2007-07-30 | 2014-02-11 | Covidien Lp | Cleaning device and methods |
WO2009045265A1 (en) | 2007-10-05 | 2009-04-09 | Maquet Cardiovascular, Llc | Devices and methods for minimally-invasive surgical procedures |
US8906011B2 (en) | 2007-11-16 | 2014-12-09 | Kardium Inc. | Medical device for use in bodily lumens, for example an atrium |
US10206821B2 (en) | 2007-12-20 | 2019-02-19 | Acclarent, Inc. | Eustachian tube dilation balloon with ventilation path |
WO2009086448A1 (en) | 2007-12-28 | 2009-07-09 | Salient Surgical Technologies, Inc. | Fluid-assisted electrosurgical devices, methods and systems |
US8483831B1 (en) | 2008-02-15 | 2013-07-09 | Holaira, Inc. | System and method for bronchial dilation |
US8182432B2 (en) | 2008-03-10 | 2012-05-22 | Acclarent, Inc. | Corewire design and construction for medical devices |
EP2529686B1 (en) | 2008-05-09 | 2015-10-14 | Holaira, Inc. | System for treating a bronchial tree |
WO2009140359A2 (en) | 2008-05-13 | 2009-11-19 | Medtronic, Inc. | Tissue lesion evaluation |
EP2664350B1 (en) | 2008-07-30 | 2019-08-28 | Acclarent, Inc. | Paranasal ostium finder devices |
WO2010033629A1 (en) | 2008-09-18 | 2010-03-25 | Acclarent, Inc. | Methods and apparatus for treating disorders of the ear nose and throat |
US20100160906A1 (en) * | 2008-12-23 | 2010-06-24 | Asthmatx, Inc. | Expandable energy delivery devices having flexible conductive elements and associated systems and methods |
US20100168717A1 (en) * | 2008-12-30 | 2010-07-01 | Grasse Martin M | Multi-lumen medical devices and methods of manufacturing same |
US8372033B2 (en) * | 2008-12-31 | 2013-02-12 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Catheter having proximal heat sensitive deflection mechanism and related methods of use and manufacturing |
US9254168B2 (en) | 2009-02-02 | 2016-02-09 | Medtronic Advanced Energy Llc | Electro-thermotherapy of tissue using penetrating microelectrode array |
JP5693471B2 (en) | 2009-02-11 | 2015-04-01 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | Insulated ablation catheter device and use thereof |
JP5592409B2 (en) | 2009-02-23 | 2014-09-17 | サリエント・サージカル・テクノロジーズ・インコーポレーテッド | Fluid-assisted electrosurgical device and method of use thereof |
US20100241155A1 (en) | 2009-03-20 | 2010-09-23 | Acclarent, Inc. | Guide system with suction |
US20100249815A1 (en) * | 2009-03-25 | 2010-09-30 | Cook Incorporated | Everted sheath thrombectomy device |
US7978742B1 (en) | 2010-03-24 | 2011-07-12 | Corning Incorporated | Methods for operating diode lasers |
US8435290B2 (en) | 2009-03-31 | 2013-05-07 | Acclarent, Inc. | System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx |
US8414579B2 (en) | 2009-06-30 | 2013-04-09 | Boston Scientific Scimed, Inc. | Map and ablate open irrigated hybrid catheter |
WO2011017189A1 (en) * | 2009-08-04 | 2011-02-10 | Wilson-Cook Medical Inc. | Roll sleeve mechanism for proximal release stent delivery device |
JP2013503723A (en) | 2009-09-08 | 2013-02-04 | サリエント・サージカル・テクノロジーズ・インコーポレーテッド | Cartridge assembly for electrosurgical devices, electrosurgical units, and methods of use thereof |
US9750563B2 (en) | 2009-09-22 | 2017-09-05 | Mederi Therapeutics, Inc. | Systems and methods for treating tissue with radiofrequency energy |
US10386990B2 (en) | 2009-09-22 | 2019-08-20 | Mederi Rf, Llc | Systems and methods for treating tissue with radiofrequency energy |
US9474565B2 (en) | 2009-09-22 | 2016-10-25 | Mederi Therapeutics, Inc. | Systems and methods for treating tissue with radiofrequency energy |
US9775664B2 (en) | 2009-09-22 | 2017-10-03 | Mederi Therapeutics, Inc. | Systems and methods for treating tissue with radiofrequency energy |
WO2011037621A2 (en) | 2009-09-22 | 2011-03-31 | Mederi Therapeutics Inc. | Systems and methods for controlling use and operation of a family of different treatment devices |
US8696653B2 (en) | 2009-10-02 | 2014-04-15 | Cardiofocus, Inc. | Cardiac ablation system with pulsed aiming light |
WO2011044248A2 (en) | 2009-10-06 | 2011-04-14 | Cardiofocus, Inc. | Cardiac ablation image analysis system and process |
US8308723B2 (en) * | 2009-10-09 | 2012-11-13 | Coaptus Medical Corporation | Tissue-penetrating guidewires with shaped tips, and associated systems and methods |
US8617228B2 (en) * | 2009-10-23 | 2013-12-31 | Medtronic Cryocath Lp | Method and system for preventing nerve injury during a medical procedure |
US9649153B2 (en) | 2009-10-27 | 2017-05-16 | Holaira, Inc. | Delivery devices with coolable energy emitting assemblies |
US10660697B2 (en) | 2009-11-10 | 2020-05-26 | Cardea Medsystems (Tianjin) Co., Ltd. | Hollow body cavity ablation apparatus |
WO2011059487A2 (en) | 2009-11-10 | 2011-05-19 | Cardea MedSystems, Inc. | Hollow body cavity ablation apparatus |
CA2780608C (en) | 2009-11-11 | 2019-02-26 | Innovative Pulmonary Solutions, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
US8911439B2 (en) | 2009-11-11 | 2014-12-16 | Holaira, Inc. | Non-invasive and minimally invasive denervation methods and systems for performing the same |
US20110213260A1 (en) * | 2010-02-26 | 2011-09-01 | Pacesetter, Inc. | Crt lead placement based on optimal branch selection and optimal site selection |
WO2011112991A1 (en) | 2010-03-11 | 2011-09-15 | Salient Surgical Technologies, Inc. | Bipolar electrosurgical cutter with position insensitive return electrode contact |
US20110295249A1 (en) * | 2010-05-28 | 2011-12-01 | Salient Surgical Technologies, Inc. | Fluid-Assisted Electrosurgical Devices, and Methods of Manufacture Thereof |
US9138289B2 (en) | 2010-06-28 | 2015-09-22 | Medtronic Advanced Energy Llc | Electrode sheath for electrosurgical device |
US8920417B2 (en) | 2010-06-30 | 2014-12-30 | Medtronic Advanced Energy Llc | Electrosurgical devices and methods of use thereof |
US8906012B2 (en) | 2010-06-30 | 2014-12-09 | Medtronic Advanced Energy Llc | Electrosurgical devices with wire electrode |
US9155492B2 (en) | 2010-09-24 | 2015-10-13 | Acclarent, Inc. | Sinus illumination lightwire device |
WO2012061164A1 (en) | 2010-10-25 | 2012-05-10 | Kevin Mauch | Catheter apparatuses having multi-electrode arrays for renal neuromodulation and associated systems and methods |
US9023040B2 (en) | 2010-10-26 | 2015-05-05 | Medtronic Advanced Energy Llc | Electrosurgical cutting devices |
US20120179097A1 (en) | 2011-01-06 | 2012-07-12 | Cully Edward H | Methods and apparatus for an adjustable stiffness catheter |
CA2764494A1 (en) | 2011-01-21 | 2012-07-21 | Kardium Inc. | Enhanced medical device for use in bodily cavities, for example an atrium |
US11259867B2 (en) | 2011-01-21 | 2022-03-01 | Kardium Inc. | High-density electrode-based medical device system |
US9480525B2 (en) | 2011-01-21 | 2016-11-01 | Kardium, Inc. | High-density electrode-based medical device system |
US9452016B2 (en) | 2011-01-21 | 2016-09-27 | Kardium Inc. | Catheter system |
US9427281B2 (en) | 2011-03-11 | 2016-08-30 | Medtronic Advanced Energy Llc | Bronchoscope-compatible catheter provided with electrosurgical device |
US10278774B2 (en) | 2011-03-18 | 2019-05-07 | Covidien Lp | Selectively expandable operative element support structure and methods of use |
AU2012246723C9 (en) * | 2011-04-22 | 2014-08-28 | Topera, Inc. | Basket style cardiac mapping catheter having an atraumatic basket tip for detection of cardiac rhythm disorders |
US9492113B2 (en) | 2011-07-15 | 2016-11-15 | Boston Scientific Scimed, Inc. | Systems and methods for monitoring organ activity |
CN103987336A (en) | 2011-09-14 | 2014-08-13 | 波士顿科学西美德公司 | Ablation device with multiple ablation modes |
US9603659B2 (en) | 2011-09-14 | 2017-03-28 | Boston Scientific Scimed Inc. | Ablation device with ionically conductive balloon |
US9750565B2 (en) | 2011-09-30 | 2017-09-05 | Medtronic Advanced Energy Llc | Electrosurgical balloons |
WO2013052852A1 (en) * | 2011-10-07 | 2013-04-11 | Boston Scientific Scimed, Inc. | Methods and systems for detection and thermal treatment of lower urinary tract conditions |
US8870864B2 (en) | 2011-10-28 | 2014-10-28 | Medtronic Advanced Energy Llc | Single instrument electrosurgery apparatus and its method of use |
AU2013207994B2 (en) | 2012-01-10 | 2015-05-07 | Boston Scientific Scimed, Inc. | Electrophysiology system |
USD777925S1 (en) | 2012-01-20 | 2017-01-31 | Kardium Inc. | Intra-cardiac procedure device |
USD777926S1 (en) | 2012-01-20 | 2017-01-31 | Kardium Inc. | Intra-cardiac procedure device |
US9168080B2 (en) | 2012-01-27 | 2015-10-27 | Medtronic Cryocath Lp | Balloon catheter |
WO2013115941A1 (en) | 2012-01-31 | 2013-08-08 | Boston Scientific Scimed, Inc. | Ablation probe with fluid-based acoustic coupling for ultrasonic tissue imaging |
US8403927B1 (en) | 2012-04-05 | 2013-03-26 | William Bruce Shingleton | Vasectomy devices and methods |
BR112014028131A2 (en) | 2012-05-11 | 2017-06-27 | Medtronic Ardian Luxembourg | catheter apparatus, renal neuromodulation system, and method for performing renal neuromodulation |
EP2854682B1 (en) | 2012-06-04 | 2021-06-23 | Boston Scientific Scimed, Inc. | Systems for treating tissue of a passageway within a body |
US9144459B2 (en) * | 2012-07-19 | 2015-09-29 | Cook Medical Technologies Llc | Endoscopic ultrasound ablation needle |
EP2877113B1 (en) | 2012-07-24 | 2018-07-25 | Boston Scientific Scimed, Inc. | Electrodes for tissue treatment |
US9592036B2 (en) * | 2012-08-08 | 2017-03-14 | Boston Scientific Scimed, Inc. | Multi-functional tissue manipulation medical device and related methods of use |
WO2014047068A1 (en) | 2012-09-18 | 2014-03-27 | Boston Scientific Scimed, Inc. | Map and ablate closed-loop cooled ablation catheter |
DE102012109387A1 (en) * | 2012-10-02 | 2014-04-03 | Aesculap Ag | Surgical instrument and in particular electrosurgical instrument |
US20140107453A1 (en) * | 2012-10-15 | 2014-04-17 | Boston Scientific Scimed Inc. | Real-time signal comparison to guide ablation catheter to the target location |
US10342608B2 (en) * | 2012-10-18 | 2019-07-09 | The Board Of Trustees Of The Leland Stanford Junior University | Ablation catheter system and method for deploying same |
US9272132B2 (en) | 2012-11-02 | 2016-03-01 | Boston Scientific Scimed, Inc. | Medical device for treating airways and related methods of use |
WO2014071372A1 (en) | 2012-11-05 | 2014-05-08 | Boston Scientific Scimed, Inc. | Devices for delivering energy to body lumens |
US9095321B2 (en) | 2012-11-21 | 2015-08-04 | Medtronic Ardian Luxembourg S.A.R.L. | Cryotherapeutic devices having integral multi-helical balloons and methods of making the same |
US9398933B2 (en) | 2012-12-27 | 2016-07-26 | Holaira, Inc. | Methods for improving drug efficacy including a combination of drug administration and nerve modulation |
US9474486B2 (en) * | 2013-03-08 | 2016-10-25 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Basket for a multi-electrode array catheter |
US9179974B2 (en) | 2013-03-15 | 2015-11-10 | Medtronic Ardian Luxembourg S.A.R.L. | Helical push wire electrode |
US9629684B2 (en) | 2013-03-15 | 2017-04-25 | Acclarent, Inc. | Apparatus and method for treatment of ethmoid sinusitis |
US9433437B2 (en) | 2013-03-15 | 2016-09-06 | Acclarent, Inc. | Apparatus and method for treatment of ethmoid sinusitis |
US9814618B2 (en) | 2013-06-06 | 2017-11-14 | Boston Scientific Scimed, Inc. | Devices for delivering energy and related methods of use |
EP3030182B1 (en) | 2013-08-09 | 2018-01-10 | Boston Scientific Scimed, Inc. | Expandable catheter |
US10064564B2 (en) | 2013-08-23 | 2018-09-04 | Medtronic Cryocath Lp | Method of CMAP monitoring |
US20150073515A1 (en) | 2013-09-09 | 2015-03-12 | Medtronic Ardian Luxembourg S.a.r.I. | Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods |
US10631914B2 (en) | 2013-09-30 | 2020-04-28 | Covidien Lp | Bipolar electrosurgical instrument with movable electrode and related systems and methods |
US9848954B2 (en) | 2013-12-20 | 2017-12-26 | Corbin E. Barnett | Surgical system and related methods |
CA2940543A1 (en) * | 2014-02-26 | 2015-09-03 | Sunnybrook Research Institute | Device and method for virtual angiography |
JP2017513600A (en) | 2014-04-24 | 2017-06-01 | メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ | Nerve adjustment catheter with braided shaft and related systems and methods |
EP3137007A4 (en) | 2014-04-28 | 2017-09-27 | Cardiofocus, Inc. | System and method for visualizing tissue with an icg dye composition during ablation procedures |
US9968370B2 (en) | 2014-05-28 | 2018-05-15 | Kyphon SÀRL | Multi-tine cutting device |
US9974599B2 (en) | 2014-08-15 | 2018-05-22 | Medtronic Ps Medical, Inc. | Multipurpose electrosurgical device |
EP3191164A4 (en) * | 2014-09-12 | 2018-08-15 | X-Rhythm, LLC | Multi-electrode mapping catheter |
US10524684B2 (en) | 2014-10-13 | 2020-01-07 | Boston Scientific Scimed Inc | Tissue diagnosis and treatment using mini-electrodes |
US10603105B2 (en) | 2014-10-24 | 2020-03-31 | Boston Scientific Scimed Inc | Medical devices with a flexible electrode assembly coupled to an ablation tip |
US9956029B2 (en) | 2014-10-31 | 2018-05-01 | Medtronic Advanced Energy Llc | Telescoping device with saline irrigation line |
EP3226744A4 (en) | 2014-12-03 | 2018-08-08 | Cardiofocus, Inc. | System and method for visual confirmation of pulmonary vein isolation during ablation procedures |
WO2016094367A2 (en) * | 2014-12-08 | 2016-06-16 | The Johns Hopkins University | Endoscopic gastric mucosal ablation/resection/exclusion (a/r/e) as a minimally invasive weight loss approach |
US9743854B2 (en) | 2014-12-18 | 2017-08-29 | Boston Scientific Scimed, Inc. | Real-time morphology analysis for lesion assessment |
US11389227B2 (en) | 2015-08-20 | 2022-07-19 | Medtronic Advanced Energy Llc | Electrosurgical device with multivariate control |
US11051875B2 (en) | 2015-08-24 | 2021-07-06 | Medtronic Advanced Energy Llc | Multipurpose electrosurgical device |
US10687890B2 (en) | 2015-10-13 | 2020-06-23 | Biosense Webster (Israel) Ltd. | Lasso catheter with moveable ablation spine |
US10675462B2 (en) | 2015-11-04 | 2020-06-09 | Boston Scientific Scimed, Inc. | Medical device and related methods |
US10716612B2 (en) | 2015-12-18 | 2020-07-21 | Medtronic Advanced Energy Llc | Electrosurgical device with multiple monopolar electrode assembly |
EP3399934B1 (en) | 2016-01-05 | 2022-10-12 | Cardiofocus, Inc. | Ablation system with automated sweeping ablation energy element |
WO2017192948A1 (en) * | 2016-05-05 | 2017-11-09 | Analog Devices, Inc. | Coordination/control of multiple medical devices at a site |
KR102067773B1 (en) * | 2016-08-25 | 2020-01-17 | 주식회사 한독칼로스메디칼 | Catheter for denervation |
USD851245S1 (en) | 2017-04-14 | 2019-06-11 | Cardiofocus, Inc. | Compliant balloon |
US10194975B1 (en) | 2017-07-11 | 2019-02-05 | Medtronic Advanced Energy, Llc | Illuminated and isolated electrosurgical apparatus |
US11389236B2 (en) | 2018-01-15 | 2022-07-19 | Cardiofocus, Inc. | Ablation system with automated ablation energy element |
US11045628B2 (en) | 2018-12-11 | 2021-06-29 | Biosense Webster (Israel) Ltd. | Balloon catheter with high articulation |
US11850051B2 (en) | 2019-04-30 | 2023-12-26 | Biosense Webster (Israel) Ltd. | Mapping grid with high density electrode array |
US11950930B2 (en) | 2019-12-12 | 2024-04-09 | Biosense Webster (Israel) Ltd. | Multi-dimensional acquisition of bipolar signals from a catheter |
US11517218B2 (en) | 2019-12-20 | 2022-12-06 | Biosense Webster (Israel) Ltd. | Selective graphical presentation of electrophysiological parameters |
US11950840B2 (en) | 2020-09-22 | 2024-04-09 | Biosense Webster (Israel) Ltd. | Basket catheter having insulated ablation electrodes |
US11950841B2 (en) | 2020-09-22 | 2024-04-09 | Biosense Webster (Israel) Ltd. | Basket catheter having insulated ablation electrodes and diagnostic electrodes |
US11918383B2 (en) | 2020-12-21 | 2024-03-05 | Biosense Webster (Israel) Ltd. | Visualizing performance of catheter electrodes |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4308164A (en) * | 1980-08-04 | 1981-12-29 | General Electric Company | Novel yellow azo dyes and dichroic liquid crystal composition made therewith |
US4758222A (en) * | 1985-05-03 | 1988-07-19 | Mccoy William C | Steerable and aimable catheter |
US4543090A (en) * | 1983-10-31 | 1985-09-24 | Mccoy William C | Steerable and aimable catheter |
US4660571A (en) * | 1985-07-18 | 1987-04-28 | Cordis Corporation | Percutaneous lead having radially adjustable electrode |
US4699147A (en) * | 1985-09-25 | 1987-10-13 | Cordis Corporation | Intraventricular multielectrode cardial mapping probe and method for using same |
US4785815A (en) * | 1985-10-23 | 1988-11-22 | Cordis Corporation | Apparatus for locating and ablating cardiac conduction pathways |
US4641649A (en) * | 1985-10-30 | 1987-02-10 | Rca Corporation | Method and apparatus for high frequency catheter ablation |
US4940064A (en) * | 1986-11-14 | 1990-07-10 | Desai Jawahar M | Catheter for mapping and ablation and method therefor |
US4808164A (en) * | 1987-08-24 | 1989-02-28 | Progressive Angioplasty Systems, Inc. | Catheter for balloon angioplasty |
US4832048A (en) * | 1987-10-29 | 1989-05-23 | Cordis Corporation | Suction ablation catheter |
US4998916A (en) * | 1989-01-09 | 1991-03-12 | Hammerslag Julius G | Steerable medical device |
US4928689A (en) * | 1989-05-15 | 1990-05-29 | Cardiac Pacemakers, Inc. | Rate adaptive cardiac pacer system having living cell tissue for sensing physiologic demand |
US4934340A (en) * | 1989-06-08 | 1990-06-19 | Hemo Laser Corporation | Device for guiding medical catheters and scopes |
US5019040A (en) * | 1989-08-31 | 1991-05-28 | Koshin Sangyo Kabushiki Kaisha | Catheter |
US5156151A (en) * | 1991-02-15 | 1992-10-20 | Cardiac Pathways Corporation | Endocardial mapping and ablation system and catheter probe |
US5415166A (en) * | 1991-02-15 | 1995-05-16 | Cardiac Pathways Corporation | Endocardial mapping apparatus and cylindrical semiconductor device mounting structure for use therewith and method |
US5152748A (en) * | 1991-03-04 | 1992-10-06 | Philippe Chastagner | Medical catheters thermally manipulated by fiber optic bundles |
WO1994002077A2 (en) * | 1992-07-15 | 1994-02-03 | Angelase, Inc. | Ablation catheter system |
US5330466A (en) * | 1992-12-01 | 1994-07-19 | Cardiac Pathways Corporation | Control mechanism and system and method for steering distal extremity of a flexible elongate member |
US5476495A (en) * | 1993-03-16 | 1995-12-19 | Ep Technologies, Inc. | Cardiac mapping and ablation systems |
US5409000A (en) * | 1993-09-14 | 1995-04-25 | Cardiac Pathways Corporation | Endocardial mapping and ablation system utilizing separately controlled steerable ablation catheter with ultrasonic imaging capabilities and method |
US5487385A (en) * | 1993-12-03 | 1996-01-30 | Avitall; Boaz | Atrial mapping and ablation catheter system |
US5595183A (en) * | 1995-02-17 | 1997-01-21 | Ep Technologies, Inc. | Systems and methods for examining heart tissue employing multiple electrode structures and roving electrodes |
-
1992
- 1992-06-05 US US07/894,529 patent/US5324284A/en not_active Expired - Lifetime
-
1993
- 1993-06-02 CA CA002097573A patent/CA2097573A1/en not_active Abandoned
- 1993-06-07 JP JP5136188A patent/JPH06142106A/en active Pending
- 1993-06-07 AT AT93304397T patent/ATE142114T1/en not_active IP Right Cessation
- 1993-06-07 DE DE69304424T patent/DE69304424T2/en not_active Expired - Fee Related
- 1993-06-07 EP EP93304397A patent/EP0573311B1/en not_active Expired - Lifetime
-
1995
- 1995-05-11 US US08/439,663 patent/US5578007A/en not_active Expired - Lifetime
-
1996
- 1996-08-28 US US08/697,632 patent/US5782899A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU668393B2 (en) | 1996-05-02 |
EP0573311B1 (en) | 1996-09-04 |
US5578007A (en) | 1996-11-26 |
DE69304424D1 (en) | 1996-10-10 |
EP0573311A1 (en) | 1993-12-08 |
JPH06142106A (en) | 1994-05-24 |
US5782899A (en) | 1998-07-21 |
US5324284A (en) | 1994-06-28 |
ATE142114T1 (en) | 1996-09-15 |
AU3992893A (en) | 1993-12-09 |
DE69304424T2 (en) | 1997-03-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5324284A (en) | Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and method | |
US6241726B1 (en) | Catheter system having a tip section with fixation means | |
US5354297A (en) | Biplanar deflectable catheter for arrhythmogenic tissue ablation | |
US5868741A (en) | Ablation catheter system having fixation tines | |
US5507802A (en) | Method of mapping and/or ablation using a catheter having a tip with fixation means | |
US5637090A (en) | Multiple electrode element for mapping and ablating heart tissue | |
EP1323451B1 (en) | System for atrial defibrillation | |
US4940064A (en) | Catheter for mapping and ablation and method therefor | |
US5779715A (en) | Lead extraction system and methods thereof | |
CA2304607C (en) | Systems for recording the use of cardiac devices | |
US5891138A (en) | Catheter system having parallel electrodes | |
CA2835769C (en) | Lasso catheter with tip electrode | |
US5893885A (en) | Multi-electrode ablation catheter | |
US6308091B1 (en) | Mapping and ablation catheter system | |
US5083565A (en) | Electrosurgical instrument for ablating endocardial tissue | |
US5860920A (en) | Systems for locating and ablating accessory pathways in the heart | |
US6156033A (en) | Ablation catheter having electrode means and methods thereof | |
US6475214B1 (en) | Catheter with enhanced ablation electrode | |
US5921924A (en) | Mapping and ablation catheter system utilizing multiple control elements | |
US6671561B1 (en) | Catheter with electrode having hydrogel layer | |
JPH11262530A (en) | Catheter with irrigatable tip | |
WO2001082814B1 (en) | Apparatus and methods for mapping and ablation in electrophysiology procedures | |
WO1995010226A1 (en) | Locating and ablating pathways in the heart |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |