CA2101245A1 - Dosage forms comprising polymers comprising different molecular weights - Google Patents
Dosage forms comprising polymers comprising different molecular weightsInfo
- Publication number
- CA2101245A1 CA2101245A1 CA002101245A CA2101245A CA2101245A1 CA 2101245 A1 CA2101245 A1 CA 2101245A1 CA 002101245 A CA002101245 A CA 002101245A CA 2101245 A CA2101245 A CA 2101245A CA 2101245 A1 CA2101245 A1 CA 2101245A1
- Authority
- CA
- Canada
- Prior art keywords
- polymers
- dosage forms
- molecular weights
- different molecular
- dosage form
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Abstract
A dosage form (10)is disclosed comprising a wall (12) surrounding a compartment (IS), which comprises a first composi-tion (16) comprising a carboxymethylcellulose (17) and a second composition (20) comprising a higher molecular weight carbox-ymethylcellulose (21).The first composition comprises a dosage amount of drug (16) that delivers from the dosage form (10) at a controlled rate over time.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US688,807 | 1991-04-22 | ||
US07/688,807 US5208037A (en) | 1991-04-22 | 1991-04-22 | Dosage forms comprising polymers comprising different molecular weights |
PCT/US1992/003294 WO1992018102A1 (en) | 1991-04-22 | 1992-04-22 | Dosage forms comprising polymers comprising different molecular weights |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2101245A1 true CA2101245A1 (en) | 1992-10-23 |
CA2101245C CA2101245C (en) | 2002-06-25 |
Family
ID=24765867
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002101245A Expired - Fee Related CA2101245C (en) | 1991-04-22 | 1992-04-22 | Dosage forms comprising polymers comprising different molecular weights |
Country Status (17)
Country | Link |
---|---|
US (2) | US5208037A (en) |
EP (1) | EP0581862B1 (en) |
JP (1) | JP2638303B2 (en) |
KR (1) | KR0158466B1 (en) |
AT (1) | ATE142481T1 (en) |
AU (1) | AU655827B2 (en) |
CA (1) | CA2101245C (en) |
DE (1) | DE69213729T2 (en) |
ES (1) | ES2092115T3 (en) |
FI (1) | FI110160B (en) |
IE (1) | IE921269A1 (en) |
MX (1) | MX9201813A (en) |
NO (1) | NO306976B1 (en) |
NZ (1) | NZ242419A (en) |
PT (1) | PT100417B (en) |
WO (1) | WO1992018102A1 (en) |
ZA (1) | ZA922907B (en) |
Families Citing this family (59)
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---|---|---|---|---|
US6764697B1 (en) * | 1991-06-27 | 2004-07-20 | Alza Corporation | System for delaying drug delivery up to seven hours |
HUT75616A (en) * | 1992-03-17 | 1997-05-28 | Pfizer | Method for prooucing porous delivery devices |
US6440457B1 (en) * | 1993-05-27 | 2002-08-27 | Alza Corporation | Method of administering antidepressant dosage form |
ZA953078B (en) * | 1994-04-28 | 1996-01-05 | Alza Corp | Effective therapy for epilepsies |
US5529787A (en) * | 1994-07-07 | 1996-06-25 | Alza Corporation | Hydromorphone therapy |
US5914131A (en) * | 1994-07-07 | 1999-06-22 | Alza Corporation | Hydromorphone therapy |
DE69709646T2 (en) * | 1996-03-12 | 2002-08-14 | Alza Corp | COMPOSITION AND DOSAGE WITH AN OPIOID ANTAGONIST |
US6919373B1 (en) | 1996-11-12 | 2005-07-19 | Alza Corporation | Methods and devices for providing prolonged drug therapy |
ZA979605B (en) * | 1996-11-25 | 1998-05-21 | Alza Corp | Ascending-dose dosage form. |
JP5173089B2 (en) * | 1996-11-25 | 2013-03-27 | アルザ コーポレイション | Increasing dose drug dosage form |
EP1782798A3 (en) | 1996-11-25 | 2008-05-21 | Alza Corporation | Ascending-dose dosage form |
US20070185032A1 (en) * | 1996-12-11 | 2007-08-09 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
US5968895A (en) * | 1996-12-11 | 1999-10-19 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
US5922352A (en) * | 1997-01-31 | 1999-07-13 | Andrx Pharmaceuticals, Inc. | Once daily calcium channel blocker tablet having a delayed release core |
US5837379A (en) * | 1997-01-31 | 1998-11-17 | Andrx Pharmaceuticals, Inc. | Once daily pharmaceutical tablet having a unitary core |
GT199800127A (en) * | 1997-08-29 | 2000-02-01 | THERAPEUTIC COMBINATIONS. | |
US6485748B1 (en) | 1997-12-12 | 2002-11-26 | Andrx Pharmaceuticals, Inc. | Once daily pharmaceutical tablet having a unitary core |
US6224907B1 (en) * | 1998-03-06 | 2001-05-01 | Alza Corporation | Anti-asthma therapy |
US6524620B2 (en) | 1998-07-20 | 2003-02-25 | Andrx Pharmaceuticals, Inc. | Diltiazem controlled release formulation and method of manufacture |
US20060153914A1 (en) * | 1999-12-10 | 2006-07-13 | Biovail Laboratories International S.R.L. | Chronotherapeutic diltiazem formulations and the administration thereof |
US7108866B1 (en) | 1999-12-10 | 2006-09-19 | Biovall Laboratories International Srl | Chronotherapeutic diltiazem formulations and the administration thereof |
JP2003518487A (en) | 1999-12-23 | 2003-06-10 | ファイザー・プロダクツ・インク | Hydrogel-driven laminated drug formulation |
ES2233611T3 (en) | 2000-02-04 | 2005-06-16 | Alza Corporation | OSMOTIC DRIVE FLUID DISPENSER. |
US7838032B2 (en) * | 2000-04-28 | 2010-11-23 | Reckitt Benckiser Inc. | Sustained release of guaifenesin |
US6372252B1 (en) | 2000-04-28 | 2002-04-16 | Adams Laboratories, Inc. | Guaifenesin sustained release formulation and tablets |
US8012504B2 (en) * | 2000-04-28 | 2011-09-06 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
US6955821B2 (en) | 2000-04-28 | 2005-10-18 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
US7985420B2 (en) * | 2000-04-28 | 2011-07-26 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
US20040001886A1 (en) * | 2001-10-17 | 2004-01-01 | Dr. Reddy's Laboratories Limited | Stabilized pharmaceutical formulations containing amlodipine maleate |
US20030185882A1 (en) * | 2001-11-06 | 2003-10-02 | Vergez Juan A. | Pharmaceutical compositions containing oxybutynin |
US8329217B2 (en) | 2001-11-06 | 2012-12-11 | Osmotica Kereskedelmi Es Szolgaltato Kft | Dual controlled release dosage form |
US7700074B2 (en) * | 2002-02-07 | 2010-04-20 | Pettegrew Jay W | Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism |
US8894973B2 (en) * | 2002-02-07 | 2014-11-25 | Jay W. Pettegrew | Method and system for differential diagnosis of chronic schizophrenia and chronic alcoholism |
US20100010336A1 (en) * | 2002-02-07 | 2010-01-14 | Pettegrew Jay W | Method and system for diagnosis of neuropsychiatric disorders including attention deficit hyperactivity disorder (adhd), autism, and schizophrenia |
MXPA04007506A (en) * | 2002-02-07 | 2004-11-10 | Sigma Tau Ind Farmaceuti | Carnitine in the treatment of geriatric depression. |
US20050272812A1 (en) * | 2002-02-07 | 2005-12-08 | Pettegrew Jay W | Methor for use of acetyl-L-carnitine (ALCAR) for treatment of depressive disorders in humans |
US7407778B2 (en) * | 2002-02-07 | 2008-08-05 | Pettegrew Jay W | Compounds, compositions and methods for treating neuropsychiatric disorders |
GB0203296D0 (en) * | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
US20040005359A1 (en) * | 2002-06-27 | 2004-01-08 | Cheng Xiu Xiu | Controlled release oral dosage form |
US8637512B2 (en) * | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
DK1551372T3 (en) | 2002-09-20 | 2018-07-23 | Alpharma Pharmaceuticals Llc | SEQUERATION SUBSTANCES AND RELATED COMPOSITIONS AND PROCEDURES |
US20060193825A1 (en) * | 2003-04-29 | 2006-08-31 | Praecis Phamaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
US20050112087A1 (en) * | 2003-04-29 | 2005-05-26 | Musso Gary F. | Pharmaceutical formulations for sustained drug delivery |
CA2956645A1 (en) | 2003-07-12 | 2005-03-31 | David A. Goldberg | Sensitive and rapid biodetection |
US20120077206A1 (en) | 2003-07-12 | 2012-03-29 | Accelr8 Technology Corporation | Rapid Microbial Detection and Antimicrobial Susceptibility Testing |
CN101677963B (en) | 2006-06-19 | 2012-05-30 | 奥尔制药公司 | Pharmaceutical compositions |
CN100563637C (en) * | 2006-10-13 | 2009-12-02 | 北京红林制药有限公司 | A kind of medicated core compositions of controlled release drug administration and controlled release preparation and preparation method thereof |
CN100563638C (en) * | 2006-10-24 | 2009-12-02 | 北京红林制药有限公司 | Nifedipine controlled-release tablet and preparation method thereof |
AU2008303129B2 (en) | 2007-09-25 | 2013-08-01 | Formulex Pharma Innovations Ltd. | Compositions comprising lipophilic active compounds and method for their preparation |
US8623418B2 (en) | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
WO2012071220A1 (en) * | 2010-11-23 | 2012-05-31 | Transcept Pharmaceuticals, Inc. | Compositions and methods for once-daily administration of a trilayer osmotic tablet |
WO2012122314A2 (en) | 2011-03-07 | 2012-09-13 | Accelr8 Technology Corporation | Rapid cell purification systems |
US10254204B2 (en) | 2011-03-07 | 2019-04-09 | Accelerate Diagnostics, Inc. | Membrane-assisted purification |
US9677109B2 (en) | 2013-03-15 | 2017-06-13 | Accelerate Diagnostics, Inc. | Rapid determination of microbial growth and antimicrobial susceptibility |
CA2932290C (en) | 2013-12-06 | 2023-06-13 | Durect Corporation | Compositions comprising antioxidant, fluid dispensers, and methods involving the same |
US10253355B2 (en) | 2015-03-30 | 2019-04-09 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing |
US10023895B2 (en) | 2015-03-30 | 2018-07-17 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing |
US11278506B2 (en) | 2015-10-09 | 2022-03-22 | Rb Health (Us) Llc | Pharmaceutical formulation |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4111202A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
US4765989A (en) * | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
NZ206600A (en) * | 1983-05-11 | 1987-01-23 | Alza Corp | Osmotic drug delivery device |
US4783337A (en) * | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
GB2140487B (en) * | 1983-05-25 | 1987-03-11 | Baker Ham & Co Ltd | Improvements relating to penstocks |
US4717566A (en) * | 1984-03-19 | 1988-01-05 | Alza Corporation | Dosage system and method of using same |
US4863456A (en) * | 1986-04-30 | 1989-09-05 | Alza Corporation | Dosage form with improved delivery capability |
US4743248A (en) * | 1986-08-11 | 1988-05-10 | Alza Corporation | Dosage form for delivering acid sensitive beneficial agent |
US4950486A (en) * | 1987-10-02 | 1990-08-21 | Alza Corporation | Dosage form for treating cardiovascular diseases |
US4946687A (en) * | 1987-10-02 | 1990-08-07 | Alza Corporation | Dosage form for treating cardiovascular diseases |
US4816263A (en) * | 1987-10-02 | 1989-03-28 | Alza Corporation | Dosage form for treating cardiovascular diseases comprising isradipine |
US4904474A (en) * | 1988-01-25 | 1990-02-27 | Alza Corporation | Delivery of drug to colon by oral disage form |
US4837111A (en) * | 1988-03-21 | 1989-06-06 | Alza Corporation | Dosage form for dispensing drug for human therapy |
US4966769A (en) * | 1988-06-02 | 1990-10-30 | Alza Corporation | Method for delivering dosage form for diltiazem |
US4859470A (en) * | 1988-06-02 | 1989-08-22 | Alza Corporation | Dosage form for delivering diltiazem |
US4902514A (en) * | 1988-07-21 | 1990-02-20 | Alza Corporation | Dosage form for administering nilvadipine for treating cardiovascular symptoms |
US4948593A (en) * | 1989-05-15 | 1990-08-14 | Alza Corporation | Osmotic dosage form comprising an estrogen and a progestogen |
US5024843A (en) * | 1989-09-05 | 1991-06-18 | Alza Corporation | Oral hypoglycemic glipizide granulation |
-
1991
- 1991-04-22 US US07/688,807 patent/US5208037A/en not_active Expired - Lifetime
-
1992
- 1992-04-20 MX MX9201813A patent/MX9201813A/en not_active IP Right Cessation
- 1992-04-22 NZ NZ24241992A patent/NZ242419A/en not_active IP Right Cessation
- 1992-04-22 DE DE69213729T patent/DE69213729T2/en not_active Expired - Fee Related
- 1992-04-22 PT PT100417A patent/PT100417B/en not_active IP Right Cessation
- 1992-04-22 ES ES92911279T patent/ES2092115T3/en not_active Expired - Lifetime
- 1992-04-22 AU AU19173/92A patent/AU655827B2/en not_active Ceased
- 1992-04-22 ZA ZA922907A patent/ZA922907B/en unknown
- 1992-04-22 AT AT92911279T patent/ATE142481T1/en active
- 1992-04-22 IE IE126992A patent/IE921269A1/en not_active IP Right Cessation
- 1992-04-22 KR KR1019930703202A patent/KR0158466B1/en not_active IP Right Cessation
- 1992-04-22 WO PCT/US1992/003294 patent/WO1992018102A1/en active IP Right Grant
- 1992-04-22 JP JP4511416A patent/JP2638303B2/en not_active Expired - Fee Related
- 1992-04-22 EP EP92911279A patent/EP0581862B1/en not_active Expired - Lifetime
- 1992-04-22 CA CA002101245A patent/CA2101245C/en not_active Expired - Fee Related
- 1992-09-04 US US07/941,332 patent/US5326571A/en not_active Expired - Lifetime
-
1993
- 1993-10-18 NO NO933728A patent/NO306976B1/en not_active IP Right Cessation
- 1993-10-21 FI FI934653A patent/FI110160B/en active
Also Published As
Publication number | Publication date |
---|---|
ZA922907B (en) | 1993-02-24 |
JPH06506952A (en) | 1994-08-04 |
FI110160B (en) | 2002-12-13 |
EP0581862A1 (en) | 1994-02-09 |
NO306976B1 (en) | 2000-01-24 |
ES2092115T3 (en) | 1996-11-16 |
PT100417A (en) | 1993-08-31 |
NZ242419A (en) | 1994-07-26 |
JP2638303B2 (en) | 1997-08-06 |
AU655827B2 (en) | 1995-01-12 |
MX9201813A (en) | 1992-10-01 |
AU1917392A (en) | 1992-11-17 |
US5326571A (en) | 1994-07-05 |
CA2101245C (en) | 2002-06-25 |
NO933728L (en) | 1993-10-18 |
PT100417B (en) | 1999-06-30 |
EP0581862B1 (en) | 1996-09-11 |
DE69213729T2 (en) | 1997-01-30 |
DE69213729D1 (en) | 1996-10-17 |
FI934653A0 (en) | 1993-10-21 |
KR0158466B1 (en) | 1998-12-01 |
US5208037A (en) | 1993-05-04 |
ATE142481T1 (en) | 1996-09-15 |
WO1992018102A1 (en) | 1992-10-29 |
IE921269A1 (en) | 1992-11-04 |
FI934653A (en) | 1993-10-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |