CA2112893A1 - Ultra-Fast Multi-Section Whole Body MRI Using Gradient and Spin Echo (GRASE) Imaging - Google Patents

Ultra-Fast Multi-Section Whole Body MRI Using Gradient and Spin Echo (GRASE) Imaging

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Publication number
CA2112893A1
CA2112893A1 CA2112893A CA2112893A CA2112893A1 CA 2112893 A1 CA2112893 A1 CA 2112893A1 CA 2112893 A CA2112893 A CA 2112893A CA 2112893 A CA2112893 A CA 2112893A CA 2112893 A1 CA2112893 A1 CA 2112893A1
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CA
Canada
Prior art keywords
gradient
whole body
grase
ultra
imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2112893A
Other languages
French (fr)
Other versions
CA2112893C (en
Inventor
David A. Feinberg
Koichi Oshio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Original Assignee
David A. Feinberg
Koichi Oshio
Brigham & Women's Hospital, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by David A. Feinberg, Koichi Oshio, Brigham & Women's Hospital, Inc. filed Critical David A. Feinberg
Publication of CA2112893A1 publication Critical patent/CA2112893A1/en
Application granted granted Critical
Publication of CA2112893C publication Critical patent/CA2112893C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
    • G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
    • G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
    • G01R33/5618—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE] using both RF and gradient refocusing, e.g. GRASE
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/565—Correction of image distortions, e.g. due to magnetic field inhomogeneities
    • G01R33/56554—Correction of image distortions, e.g. due to magnetic field inhomogeneities caused by acquiring plural, differently encoded echo signals after one RF excitation, e.g. correction for readout gradients of alternating polarity in EPI

Abstract

A fast magnetic resonance whole body imaging method and apparatus. In each of one or more repetition intervals, after an initial NMR RF (90°) nutation pulse a sequence of (180°) RF nutation pulses is used to refocus the RF response into a corre-sponding train of spin echoes (S2, S5, S8). During the time that the spin echoes would normally occur after each (180°) RF pulse, an alternating polarity read-out gradient is applied so as to form a sub-sequence of gradient echoes (S1,S3,S4,S6,S7,S9). Non-contiguous K-space trajectories of the acquired data are interleaved.
CA002112893A 1991-07-05 1992-07-06 Ultra-fast multi-section whole body mri using gradient and spin echo (grase) imaging Expired - Lifetime CA2112893C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/727,229 US5270654A (en) 1991-07-05 1991-07-05 Ultra-fast multi-section MRI using gradient and spin echo (grase) imaging
US727,229 1991-07-05

Publications (2)

Publication Number Publication Date
CA2112893A1 true CA2112893A1 (en) 1993-01-21
CA2112893C CA2112893C (en) 1996-08-27

Family

ID=24921843

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002112893A Expired - Lifetime CA2112893C (en) 1991-07-05 1992-07-06 Ultra-fast multi-section whole body mri using gradient and spin echo (grase) imaging

Country Status (7)

Country Link
US (2) US5270654A (en)
EP (1) EP0604441B1 (en)
JP (2) JP2926110B2 (en)
AU (1) AU2337092A (en)
CA (1) CA2112893C (en)
DE (1) DE69219475T2 (en)
WO (1) WO1993001509A1 (en)

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