CA2125888A1 - Pharmaceutically active antioxidant containing composition and the method of its use to prevent and treat restenosis following angioplasty - Google Patents
Pharmaceutically active antioxidant containing composition and the method of its use to prevent and treat restenosis following angioplastyInfo
- Publication number
- CA2125888A1 CA2125888A1 CA002125888A CA2125888A CA2125888A1 CA 2125888 A1 CA2125888 A1 CA 2125888A1 CA 002125888 A CA002125888 A CA 002125888A CA 2125888 A CA2125888 A CA 2125888A CA 2125888 A1 CA2125888 A1 CA 2125888A1
- Authority
- CA
- Canada
- Prior art keywords
- prevent
- pharmaceutically active
- containing composition
- restenosis following
- following angioplasty
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A61K31/51—Thiamines, e.g. vitamin B1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
The present invention relates to formulations and methods for preventing and treating restenosis following angioplasty. This is accomplished by the regimented administration of a composition which includes selected antioxidants.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81729392A | 1992-01-06 | 1992-01-06 | |
US07/817,293 | 1992-01-06 | ||
PCT/US1993/000116 WO1993013660A1 (en) | 1992-01-06 | 1993-01-04 | Pharmaceutically active antioxydant containing composition and the method of its use to prevent and treat restenosis following angioplasty |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2125888A1 true CA2125888A1 (en) | 1993-07-22 |
CA2125888C CA2125888C (en) | 2002-08-27 |
Family
ID=25222752
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002125888A Expired - Fee Related CA2125888C (en) | 1992-01-06 | 1993-01-04 | Pharmaceutically active antioxidant containing composition and the method of its use to prevent and treat restenosis following angioplasty |
Country Status (5)
Country | Link |
---|---|
US (1) | US5326757A (en) |
EP (1) | EP0746202A4 (en) |
JP (1) | JPH07503010A (en) |
CA (1) | CA2125888C (en) |
WO (1) | WO1993013660A1 (en) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU660630B2 (en) * | 1990-10-01 | 1995-07-06 | Brigham And Women's Hospital | Beta-carotene and vitamin E therapy for inhibition of major vascular events |
US6022866A (en) * | 1991-07-03 | 2000-02-08 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6306421B1 (en) | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5770609A (en) * | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6395494B1 (en) * | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
US6764693B1 (en) * | 1992-12-11 | 2004-07-20 | Amaox, Ltd. | Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants |
US5981568A (en) * | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5595722A (en) * | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
US6663881B2 (en) * | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6197789B1 (en) | 1995-06-07 | 2001-03-06 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies with tamoxifen analogues |
CA2162586C (en) | 1993-05-13 | 2006-01-03 | David J. Grainger | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
GB9314621D0 (en) * | 1993-07-14 | 1993-08-25 | Kodak Ltd | Material supply |
US5824644A (en) * | 1994-07-07 | 1998-10-20 | G. D. Searle & Co. | Method of attenuating arterial stenosis |
SE9500897D0 (en) * | 1995-03-14 | 1995-03-14 | Astra Ab | The pharmacological use of certain cysteine derivatives |
WO1996030012A1 (en) * | 1995-03-24 | 1996-10-03 | Defeudis Francis V | Methods for treating conditions associated with excess nitric oxide |
US7611533B2 (en) | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
TW565558B (en) | 1995-11-09 | 2003-12-11 | Chugai Pharmaceutical Co Ltd | Intimal thickening inhibitory agent |
US6069167A (en) * | 1996-01-16 | 2000-05-30 | University Technology Corporation | Use of antioxidant agents to treat cholestatic liver disease |
US6113935A (en) * | 1996-12-31 | 2000-09-05 | Zeneca Limited | Water-in-oil microencapsulation process and microcapsules produced thereby |
JP2001507696A (en) * | 1996-12-31 | 2001-06-12 | アンチオキシダント ファーマシューティカルズ コーポレーション | Pharmaceutical formulation of glutathione and method of administration thereof |
US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
US6201028B1 (en) | 1998-12-08 | 2001-03-13 | The Rockefeller University | Methods and compositions for prevention and treatment of atherosclerosis and hyperlipidemia with non-steroidal anti-inflammatory drugs |
US6346547B1 (en) | 1999-02-08 | 2002-02-12 | Checkpoint, Genetics, Inc. | N-substituted amino acids, antioxidant pharmaceutical compositions containing n-substituted amino acids and methods for preventing cardiovascular diseases and/or preventing and/or treating antioxidant responsive diseases therewith |
DK1169322T3 (en) | 1999-03-08 | 2006-03-06 | Medicure Inc | Pyridoxal analogues for the treatment of disorders caused by vitamin B6 deficiency |
AU5840200A (en) * | 1999-07-13 | 2001-01-30 | Medicure Inc. | Treatment of diabetes and related pathologies |
JP2003507418A (en) * | 1999-08-24 | 2003-02-25 | メディキュア インターナショナル インコーポレイテッド | Treatment of cardiovascular disease and related diseases |
WO2001056572A1 (en) * | 2000-02-02 | 2001-08-09 | Metagenics, Inc. | Compositions and methods for promoting healthy joints |
JP2003525303A (en) | 2000-02-29 | 2003-08-26 | メディキュア インターナショナル インコーポレイテッド | Cardioprotective phosphonates and malonates |
US7442689B2 (en) * | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
JP2003528146A (en) | 2000-03-28 | 2003-09-24 | メディキュア インターナショナル インコーポレイテッド | Treatment of cerebrovascular disease |
US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
WO2002004421A2 (en) | 2000-07-07 | 2002-01-17 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: cardiovascular therapeutics |
US20040121988A1 (en) * | 2001-03-28 | 2004-06-24 | Medicure International Inc. | Treatment of cerebrovascular disease |
US6596762B2 (en) | 2001-05-17 | 2003-07-22 | The Regents Of The University Of Colorado | Antioxidant compositions and use for treatment of hepatic steatosis and steatohepatitis |
US7521584B2 (en) * | 2002-07-29 | 2009-04-21 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of disease |
US20050148517A1 (en) * | 2002-07-29 | 2005-07-07 | Lockwood Samuel F. | Carotenoid ether analogs or derivatives for controlling connexin 43 expression |
US7375133B2 (en) | 2002-07-29 | 2008-05-20 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
US20050009788A1 (en) * | 2002-07-29 | 2005-01-13 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling connexin 43 expression |
US20050059635A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling C-reactive protein levels |
US20050026874A1 (en) * | 2002-07-29 | 2005-02-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease |
US20050143475A1 (en) * | 2002-07-29 | 2005-06-30 | Lockwood Samuel F. | Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury |
US20050049248A1 (en) * | 2002-07-29 | 2005-03-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for controlling C-reactive protein levels |
KR20050069975A (en) * | 2002-07-29 | 2005-07-05 | 하와이 바이오테크, 인코포레이티드 | Structural carotenoid analogs for the inhibition and amelioration of disease |
US20050004235A1 (en) * | 2002-07-29 | 2005-01-06 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease |
US7723327B2 (en) * | 2002-07-29 | 2010-05-25 | Cardax Pharmaceuticals, Inc. | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease |
US7763649B2 (en) * | 2002-07-29 | 2010-07-27 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for controlling connexin 43 expression |
US20050059659A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for controlling C-reactive protein levels |
US7320997B2 (en) * | 2002-07-29 | 2008-01-22 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease |
US7345091B2 (en) * | 2002-07-29 | 2008-03-18 | Cardax Pharmaceuticals, Inc. | Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
CN1485072A (en) * | 2002-09-28 | 2004-03-31 | Coix seed oil soft capsule for curing prostate diseases and the application thereof | |
US20040186077A1 (en) * | 2003-03-17 | 2004-09-23 | Medicure International Inc. | Novel heteroaryl phosphonates as cardioprotective agents |
US9492493B2 (en) * | 2003-09-22 | 2016-11-15 | Dapeng Li | Softgel of NLKJ for treating prostate diseases |
US20060058269A1 (en) * | 2004-04-14 | 2006-03-16 | Lockwood Samuel F | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
CA2564066A1 (en) * | 2004-04-14 | 2005-11-03 | Hawaii Biotech, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
AU2005259735A1 (en) * | 2004-07-07 | 2006-01-12 | Medicure International Inc. | Combination therapies employing platelet aggregation drugs |
US20070060549A1 (en) * | 2004-08-10 | 2007-03-15 | Friesen Albert D | Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders |
US7459468B2 (en) * | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
WO2006050598A1 (en) * | 2004-10-28 | 2006-05-18 | Medicure International Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
US20060094749A1 (en) * | 2004-10-28 | 2006-05-04 | Medicure International Inc. | Substituted pyridoxines as anti-platelet agents |
JP2009517411A (en) * | 2005-11-28 | 2009-04-30 | メディキュア インターナショナル インコーポレーテッド | Formulations for the treatment of cardiovascular and related medical conditions |
US20080139668A1 (en) * | 2006-12-12 | 2008-06-12 | Korea Research Institute Of Bioscience And Biotechnology | Pharmaceutical composition for obovatol for the prevention and treatment of restenosis |
US20160367620A1 (en) * | 2015-06-19 | 2016-12-22 | Harry B. Demopoulos | Glutathione |
MA51056A (en) * | 2017-12-07 | 2020-10-14 | Reven Ip Holdco Llc | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4454125A (en) * | 1982-04-22 | 1984-06-12 | Demopoulos Harry B | Dry powder formulations having improved flow and compressibility characteristics, and method for the preparation thereof |
EP0125252A1 (en) * | 1982-11-16 | 1984-11-21 | MOTSCHAN, Georges | New utilization of a unique vitamin or a combination of various vitamins |
DE3542309A1 (en) * | 1985-11-29 | 1987-06-04 | Cardona Federico Dr | Medicinal antioxidant |
FR2610626B1 (en) * | 1987-02-09 | 1989-05-19 | Oreal | NOVEL ANTI-OXIDIZER SYSTEM BASED ON A STABILIZED ASCORBYL ESTER, COMPRISING AT LEAST ONE COMPLEXING AGENT AND AT LEAST ONE THIOL, AND COMPOSITIONS CONTAINING SUCH ANTI-OXIDIZING SYSTEM |
WO1991002535A1 (en) * | 1989-08-11 | 1991-03-07 | Basil, Inc. | Cancer prevention composition and method |
JPH06192104A (en) * | 1992-09-14 | 1994-07-12 | Vesta Medicines Pty Ltd | Composition for curing and preventing infantile dysbolism |
-
1993
- 1993-01-04 CA CA002125888A patent/CA2125888C/en not_active Expired - Fee Related
- 1993-01-04 JP JP5512567A patent/JPH07503010A/en active Pending
- 1993-01-04 WO PCT/US1993/000116 patent/WO1993013660A1/en not_active Application Discontinuation
- 1993-01-04 EP EP93902991A patent/EP0746202A4/en not_active Withdrawn
- 1993-08-18 US US08/108,849 patent/US5326757A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0746202A4 (en) | 1997-06-25 |
US5326757A (en) | 1994-07-05 |
WO1993013660A1 (en) | 1993-07-22 |
JPH07503010A (en) | 1995-03-30 |
CA2125888C (en) | 2002-08-27 |
EP0746202A1 (en) | 1996-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2125888A1 (en) | Pharmaceutically active antioxidant containing composition and the method of its use to prevent and treat restenosis following angioplasty | |
TW376319B (en) | Pharmaceutical composition containing risperidone pamoate and having a long acting activity for treating psychoses induced by the release of dopamine | |
EP0222483A3 (en) | Use of gamma-linolenic acid and related compounds in the treatment of endometriosis | |
IE790756L (en) | Cerebral therapeutic agent | |
IL111365A0 (en) | (r)-5-carbamoyl -8-fluoro-3-n, n-disubstituted-amino-3, 4-dihydro-2h-1- benzopyrans | |
HUT72317A (en) | Use of venflaxine or 3-aryloxi-propaneamine derivatives for preparing pharmaceutical compositions for treatment of incontinence | |
EP0943328A3 (en) | Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia | |
AU4740893A (en) | Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3 | |
EP0807633A3 (en) | Novel 2,3-disubstituted-(5,6)- heteroarylfused-pyrimidine-4-ones | |
CA2157142A1 (en) | Treatment of diseases caused by sebaceous gland disorders | |
AU7263591A (en) | Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors | |
CA2173147A1 (en) | Anti-obesity agent | |
AU2713992A (en) | Therapeutic agent | |
CA2135709A1 (en) | Melatonin derivatives for use in treating sleep disorders | |
IL105475A (en) | PHARMACEUTICAL COMPOSITIONS CONTAINING 1a, 24(R) - DIHYDROXY-22(E)-DEHYDRO- VITAMIN D3 FOR TREATING OSTEOPOROSIS | |
TW325997B (en) | Pharmaceutical composition for preventing and treating retinal diseases | |
CA2135710A1 (en) | Melatonin derivatives for use in treating desynchronization disorders | |
CA2192822A1 (en) | Use of immunosuppressive agents for the treatment of schizophrenia | |
UA74388C2 (en) | Pharmaceutical compositions of tysoxanide and nitasoxanide | |
EP0618812A4 (en) | Use of protease nexin-i as an antiinflammatory. | |
LT96094A (en) | The active ingredient of pharmaceutical composition for treating constipation | |
TW330933B (en) | Furanoeremophilane and eremophilanolide sesquiterpenes for treatment of diabetes | |
IL111138A (en) | Pharmaceutical compositions comprising penciclovir and/or its bioprecursor and/or its derivatives for the treatment and prophylaxis of post-herpetic neuralgia | |
IL98394A0 (en) | Ws7622a mono or di-sulfate,salts thereof,processes for the preparation thereof and pharmaceutical compositions containing the same | |
CA2188871A1 (en) | Method for Treating Psoriasis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |