CA2128987A1 - Analyte Detection Device and Process - Google Patents

Analyte Detection Device and Process

Info

Publication number
CA2128987A1
CA2128987A1 CA2128987A CA2128987A CA2128987A1 CA 2128987 A1 CA2128987 A1 CA 2128987A1 CA 2128987 A CA2128987 A CA 2128987A CA 2128987 A CA2128987 A CA 2128987A CA 2128987 A1 CA2128987 A1 CA 2128987A1
Authority
CA
Canada
Prior art keywords
analyte
detecting
sample
separation matrix
detection device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2128987A
Other languages
French (fr)
Other versions
CA2128987C (en
Inventor
Steven C. Charlton
Michael J. Wilcox
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Inc filed Critical Miles Inc
Publication of CA2128987A1 publication Critical patent/CA2128987A1/en
Application granted granted Critical
Publication of CA2128987C publication Critical patent/CA2128987C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525Multi-layer analytical elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]
    • Y10T436/144444Glucose

Abstract

The present invention provides a device and a process for detecting an analyte in a biological fluid. That device comprises a cover portion with a restricted area for sample application, a separation matrix for separation of the analyte from substances in the sample that can interfere with detection of the analyte and means for detecting the analyte. The restricted area of sample application is less than 90 percent of the cross sectional area of the separation matrix and the separation matrix and the means for detecting analyte are under compression of between 14 to 43 percent. A process comprises applying a sample of fluid to such a device and detecting a signal generated from an interaction between the analyte and the detection means in the device.
CA002128987A 1993-08-05 1994-07-27 Analyte detection device and process Expired - Fee Related CA2128987C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/102,297 US6096269A (en) 1993-08-05 1993-08-05 Analyte detection device and process
US102,297 1993-08-05

Publications (2)

Publication Number Publication Date
CA2128987A1 true CA2128987A1 (en) 1995-02-06
CA2128987C CA2128987C (en) 1998-04-21

Family

ID=22289151

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002128987A Expired - Fee Related CA2128987C (en) 1993-08-05 1994-07-27 Analyte detection device and process

Country Status (7)

Country Link
US (1) US6096269A (en)
EP (1) EP0640392B1 (en)
JP (1) JP3439836B2 (en)
AU (1) AU670882B2 (en)
CA (1) CA2128987C (en)
DE (1) DE69424234T2 (en)
ES (1) ES2145795T3 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2441402A (en) * 2000-10-18 2002-04-29 Clarity Technologies Inc Method and device for diluting a fluid and detecting analytes within a diluted fluid
JP4191051B2 (en) * 2002-02-27 2008-12-03 三光純薬株式会社 Plasma or serum separator
US7364699B2 (en) * 2003-06-18 2008-04-29 Bayer Healthcare Llc Containers for reading and handling diagnostic reagents and methods of using the same
EP1746419A1 (en) * 2004-04-30 2007-01-24 Arkray, Inc. Sample analyzing tool
JP2006038512A (en) * 2004-07-23 2006-02-09 Fuji Photo Film Co Ltd Blood filtering glass fiber filter, blood filtering implement and blood analyzing element
RU2007114897A (en) * 2004-09-20 2008-10-27 БАЙЕР ХЕЛТКЭА ЭлЭлСи (US) BIOLOGICAL TEST STRIP
WO2006095757A1 (en) * 2005-03-09 2006-09-14 Fujifilm Corporation Multilayer analytical element
DE102005040211B4 (en) 2005-08-16 2010-02-11 Maquet Cardiopulmonary Ag Use of nonionic esters in a coating for blood contacting surfaces and medical device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4776904A (en) * 1985-07-19 1988-10-11 Miles Inc. Multilayer analytical element and method of making, using ultrasonic or laser energy
DE3530993A1 (en) * 1985-08-30 1987-03-05 Miles Lab TEST STRIP WITH DETERMINABLE SAMPLE CAPACITY
US4839296A (en) * 1985-10-18 1989-06-13 Chem-Elec, Inc. Blood plasma test method
AU590071B2 (en) * 1987-02-25 1989-10-26 Genesis Labs, Inc. Dry test strips having a red blood cell exclusion layer preventing interference by red blood cells in analyte detection visualization
US5037738A (en) * 1987-06-03 1991-08-06 Abbott Laboratories Simultaneous assay for glucose and urea
FI81120C (en) * 1988-09-26 1990-09-10 Kone Oy FOERFARANDE FOER BESTAEMNING AV GLUKOS UR BIOLOGISKA VAETSKA SAMT REAGENSBLANDNING FOER TILLAEMPNING AV FOERFARANDET.
US5087556A (en) * 1989-05-17 1992-02-11 Actimed Laboratories, Inc. Method for quantitative analysis of body fluid constituents
CA2031975A1 (en) * 1990-01-12 1991-07-13 Brian R. Barkes Device and method of separating and assaying whole blood
DE4012216A1 (en) * 1990-04-14 1991-10-17 Boehringer Mannheim Gmbh TEST CARRIER FOR THE ANALYSIS OF LIQUIDS
JPH04324347A (en) * 1991-04-24 1992-11-13 Terumo Corp Testing device

Also Published As

Publication number Publication date
JPH0755810A (en) 1995-03-03
EP0640392B1 (en) 2000-05-03
EP0640392A2 (en) 1995-03-01
US6096269A (en) 2000-08-01
JP3439836B2 (en) 2003-08-25
DE69424234T2 (en) 2000-09-07
ES2145795T3 (en) 2000-07-16
DE69424234D1 (en) 2000-06-08
CA2128987C (en) 1998-04-21
EP0640392A3 (en) 1995-11-29
AU6886094A (en) 1995-03-02
AU670882B2 (en) 1996-08-01

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20110727