CA2144209A1 - Method and apparatus for an efficient photodynamic treatment - Google Patents

Method and apparatus for an efficient photodynamic treatment

Info

Publication number
CA2144209A1
CA2144209A1 CA002144209A CA2144209A CA2144209A1 CA 2144209 A1 CA2144209 A1 CA 2144209A1 CA 002144209 A CA002144209 A CA 002144209A CA 2144209 A CA2144209 A CA 2144209A CA 2144209 A1 CA2144209 A1 CA 2144209A1
Authority
CA
Canada
Prior art keywords
treatment
photodynamic treatment
success
administration
mirror
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002144209A
Other languages
French (fr)
Other versions
CA2144209C (en
Inventor
Eli T. Talmore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ESC Medical Systems Ltd
Original Assignee
Esc Medical Systems Ltd.
Eli T. Talmore
Medic Lightech Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esc Medical Systems Ltd., Eli T. Talmore, Medic Lightech Ltd. filed Critical Esc Medical Systems Ltd.
Publication of CA2144209A1 publication Critical patent/CA2144209A1/en
Application granted granted Critical
Publication of CA2144209C publication Critical patent/CA2144209C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N2005/002Cooling systems
    • A61N2005/005Cooling systems for cooling the radiator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared

Abstract

The present invention relates to an improved apparatus for a therapeutic treatment of malignant solid tumors, consisting of a combined photodynamic therapy and hyperthermic treatment, said apparatus comprising a lamp possessing a narrow beam light, a mirror, an optical glass lenses system, a dicroic filter, a glass fiber optics bundle and an effective air-cooling system. This apparatus provides the administration of between 100 to 150 mw/cm2 of red radiation in the range of between 600 to 750 nm band at a temperature of up to 46°C. Clinical results from three different hospitals show that by this apparatus a success of more than 85% were achieved even after one single treatment.
CA002144209A 1994-03-10 1995-03-08 Method and apparatus for an efficient photodynamic treatment Expired - Fee Related CA2144209C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL108,918 1994-03-10
IL108918A IL108918A (en) 1994-03-10 1994-03-10 Apparatus for efficient photodynamic treatment

Publications (2)

Publication Number Publication Date
CA2144209A1 true CA2144209A1 (en) 1995-09-11
CA2144209C CA2144209C (en) 2001-07-31

Family

ID=11065913

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002144209A Expired - Fee Related CA2144209C (en) 1994-03-10 1995-03-08 Method and apparatus for an efficient photodynamic treatment

Country Status (6)

Country Link
US (1) US5707401A (en)
CA (1) CA2144209C (en)
DE (1) DE19507980C2 (en)
GB (1) GB2287652B (en)
IL (1) IL108918A (en)
ZA (1) ZA951948B (en)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19611251C1 (en) * 1996-03-22 1997-08-21 Heraeus Med Gmbh Method and radiation device for heating a lying surface for people
US5849027A (en) * 1996-09-04 1998-12-15 Mbg Technologies, Inc. Photodynamic therapy method and apparatus
US7353829B1 (en) * 1996-10-30 2008-04-08 Provectus Devicetech, Inc. Methods and apparatus for multi-photon photo-activation of therapeutic agents
US7036516B1 (en) * 1996-10-30 2006-05-02 Xantech Pharmaceuticals, Inc. Treatment of pigmented tissues using optical energy
US8182473B2 (en) 1999-01-08 2012-05-22 Palomar Medical Technologies Cooling system for a photocosmetic device
US20060149343A1 (en) * 1996-12-02 2006-07-06 Palomar Medical Technologies, Inc. Cooling system for a photocosmetic device
US6273884B1 (en) 1997-05-15 2001-08-14 Palomar Medical Technologies, Inc. Method and apparatus for dermatology treatment
US5957960A (en) * 1997-05-05 1999-09-28 Light Sciences Limited Partnership Internal two photon excitation device for delivery of PDT to diffuse abnormal cells
EP0885629A3 (en) 1997-06-16 1999-07-21 Danish Dermatologic Development A/S Light pulse generating apparatus and cosmetic and therapeutic phototreatment
EP1030719A4 (en) * 1997-10-30 2002-11-27 Esc Medical Systems Ltd System and method for endoscopically applying and monitoring photodynamic therapy and photodynamic diagnosis
AU3450799A (en) 1998-03-12 1999-09-27 Palomar Medical Technologies, Inc. System for electromagnetic radiation of the skin
US6223071B1 (en) * 1998-05-01 2001-04-24 Dusa Pharmaceuticals Inc. Illuminator for photodynamic therapy and diagnosis which produces substantially uniform intensity visible light
DE69940738D1 (en) * 1998-07-09 2009-05-28 Curelight Medical Ltd DEVICE AND METHOD FOR EFFICIENT HIGHERGETIC PHOTODYNAMIC THERAPY OF ACNE VULGARIS AND SEBORRHOE
US7498156B2 (en) * 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US6258577B1 (en) 1998-07-21 2001-07-10 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers
US7049110B2 (en) * 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US20070099170A1 (en) * 1998-07-21 2007-05-03 Navigant Biotechnologies, Inc. Method for treatment and storage of blood and blood products using endogenous alloxazines and acetate
US6440155B1 (en) * 1998-08-19 2002-08-27 Tokai University Educational System Device for heating a biotissue employing a strong light
US6369964B1 (en) * 1998-09-04 2002-04-09 General Scientific Corporation Optical filters for reducing eye strain, during surgery
US6936044B2 (en) * 1998-11-30 2005-08-30 Light Bioscience, Llc Method and apparatus for the stimulation of hair growth
US9192780B2 (en) * 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US20060212025A1 (en) * 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US6283956B1 (en) * 1998-11-30 2001-09-04 David H. McDaniels Reduction, elimination, or stimulation of hair growth
AU2412800A (en) * 1999-01-15 2000-08-01 Light Sciences Corporation Noninvasive vascular therapy
US6454789B1 (en) * 1999-01-15 2002-09-24 Light Science Corporation Patient portable device for photodynamic therapy
US6602274B1 (en) * 1999-01-15 2003-08-05 Light Sciences Corporation Targeted transcutaneous cancer therapy
US20040122492A1 (en) * 1999-07-07 2004-06-24 Yoram Harth Phototherapeutic treatment of skin conditions
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
EP1267935A2 (en) 2000-01-12 2003-01-02 Light Sciences Corporation Novel treatment for eye disease
GB2370992B (en) * 2000-03-23 2002-11-20 Photo Therapeutics Ltd Therapeutic light source and method
US7985588B2 (en) * 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US7648699B2 (en) * 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
US6843961B2 (en) * 2000-06-15 2005-01-18 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US20080306471A1 (en) * 2000-12-28 2008-12-11 Palomar Medical Technologies, Inc. Methods and devices for fractional ablation of tissue
US7753943B2 (en) * 2001-02-06 2010-07-13 Qlt Inc. Reduced fluence rate PDT
IL157684A0 (en) * 2001-03-02 2004-03-28 Palomar Medical Tech Inc Apparatus and method for photocosmetic and photodermatological treatment
JP2002263206A (en) * 2001-03-13 2002-09-17 Seric Ltd Phototherapy apparatus
IL158664A0 (en) 2001-05-03 2004-05-12 Adanced Light Technology Llc Differential photochemical and photomechanical processing
US7354448B2 (en) 2001-11-29 2008-04-08 Palomar Medical Technologies, Inc. Dental phototherapy methods and compositions
EP1467760A2 (en) * 2002-01-23 2004-10-20 Light Sciences Corporation Systems and methods for photodynamic therapy
US20080177359A1 (en) * 2002-05-03 2008-07-24 Advanced Light Technology, Llc. Differential photochemical and photomechanical processing
KR20050026404A (en) 2002-06-19 2005-03-15 팔로마 메디칼 테크놀로지스, 인코포레이티드 Method and apparatus for photothermal treatment of tissue at depth
US6824555B1 (en) 2002-07-22 2004-11-30 Uop Llc Combustion needle for medical applications
US6960225B1 (en) 2002-07-22 2005-11-01 Uop Llc Medical applications using microcombustion
US20040219385A1 (en) * 2002-08-23 2004-11-04 Rene Mattern Process for curing powder coatings
US20070213792A1 (en) * 2002-10-07 2007-09-13 Palomar Medical Technologies, Inc. Treatment Of Tissue Volume With Radiant Energy
EP1558339A1 (en) * 2002-10-07 2005-08-03 Palomar Medical Technologies, Inc. Apparatus for performing photobiostimulation
EP2522294A2 (en) * 2002-10-23 2012-11-14 Palomar Medical Technologies, Inc. Phototreatment device for use with coolants and topical substances
AU2003900176A0 (en) * 2003-01-16 2003-01-30 Rofin Australia Pty Ltd Photodynamic therapy light source
AU2004213047A1 (en) * 2003-02-19 2004-09-02 Palomar Medical Technologies, Inc. Method and apparatus for treating pseudofolliculitis barbae
US7354433B2 (en) * 2003-02-28 2008-04-08 Advanced Light Technologies, Llc Disinfection, destruction of neoplastic growth, and sterilization by differential absorption of electromagnetic energy
US20110040295A1 (en) * 2003-02-28 2011-02-17 Photometics, Inc. Cancer treatment using selective photo-apoptosis
CA2531099A1 (en) * 2003-04-10 2004-10-28 Light Bioscience, Llc Photomodulation methods and devices for regulating cell proliferation and gene expression
CA2533129A1 (en) * 2003-07-31 2005-02-10 Light Bioscience, Llc System and method for the photodynamic treatment of burns, wounds, and related skin disorders
CA2437638A1 (en) * 2003-08-20 2005-02-20 John Robert North Photodynamic therapy
WO2005070500A1 (en) * 2004-01-27 2005-08-04 Degeratu D Ion Cristian Medical apparatus with light flux for biological treatments
US20050167438A1 (en) * 2004-02-02 2005-08-04 Max Minyayev Secure spill-proof configuration for child training cup
US20050209330A1 (en) * 2004-03-22 2005-09-22 Syneron Medical Ltd. Method of treatment of skin
US20050209331A1 (en) * 2004-03-22 2005-09-22 Syneron Medical Ltd. Method of treatment of skin
AU2005231443B2 (en) 2004-04-01 2012-02-23 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping
US20080132886A1 (en) * 2004-04-09 2008-06-05 Palomar Medical Technologies, Inc. Use of fractional emr technology on incisions and internal tissues
EP1748740A4 (en) * 2004-04-09 2008-12-31 Palomar Medical Tech Inc Methods and products for producing lattices of emr-treated islets in tissues, and uses therefor
US20060094781A1 (en) * 2004-11-04 2006-05-04 Syneron Medical Ltd. Method of treating extracellular matrix
US7856985B2 (en) 2005-04-22 2010-12-28 Cynosure, Inc. Method of treatment body tissue using a non-uniform laser beam
CN101282692A (en) * 2005-08-08 2008-10-08 帕洛玛医疗技术公司 Eye-safe photocosmetic device
US8048064B2 (en) 2005-12-23 2011-11-01 Lutronic Corporation Method of curing inflammatory acne by using carbon lotion and pulsed laser
US8540703B2 (en) 2005-12-23 2013-09-24 Lutronic Corporation Methods for treating skin conditions using laser
KR100742973B1 (en) * 2006-02-22 2007-07-27 주식회사 루트로닉 Fatty tissue removing using 1444nm beam oscillating nd:yag laser
KR100649890B1 (en) * 2006-03-27 2006-11-28 주식회사 루트로닉 Control method and control structure of laser beam irradiation by using a contact sensor
US7586957B2 (en) 2006-08-02 2009-09-08 Cynosure, Inc Picosecond laser apparatus and methods for its operation and use
US20080186591A1 (en) * 2007-02-01 2008-08-07 Palomar Medical Technologies, Inc. Dermatological device having a zoom lens system
JP4350767B2 (en) * 2007-03-30 2009-10-21 オリンパスメディカルシステムズ株式会社 Medical equipment
WO2008154000A1 (en) * 2007-06-08 2008-12-18 Cynosure, Inc. Thermal surgery safety suite
US9919168B2 (en) 2009-07-23 2018-03-20 Palomar Medical Technologies, Inc. Method for improvement of cellulite appearance
US9034023B2 (en) * 2011-01-24 2015-05-19 Biolitec Pharma Marketing Ltd Dynamic colorectal PDT application
KR102183581B1 (en) 2012-04-18 2020-11-27 싸이노슈어, 엘엘씨 Picosecond laser apparatus and methods for treating target tissues with same
US20140271453A1 (en) 2013-03-14 2014-09-18 Abbott Laboratories Methods for the early detection of lung cancer
EP2973894A2 (en) 2013-03-15 2016-01-20 Cynosure, Inc. Picosecond optical radiation systems and methods of use
DE102013017586A1 (en) 2013-10-17 2015-05-07 Turbolite Vertriebs Gmbh TREATMENT DEVICE for Magnetic Field Assisted Irradiation Therapy
CA3045508A1 (en) 2016-12-03 2018-06-07 Juno Therapeutics, Inc. Methods for modulation of car-t cells
CA3092248A1 (en) 2018-02-26 2019-08-29 Mirko Mirkov Q-switched cavity dumped sub-nanosecond laser
CN109771840A (en) * 2019-01-14 2019-05-21 中国科学院上海硅酸盐研究所 Application of the near-infrared third window laser in the instrument that preparation is used for tumor thermal therapy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2609273A1 (en) * 1976-03-05 1977-09-08 Mutzhas Maximilian F IRRADIATION DEVICE WITH ULTRAVIOLET RADIATION SOURCE
DE2717233A1 (en) * 1977-04-19 1978-11-02 Strahlen Umweltforsch Gmbh LIGHT SOURCE
US4385344A (en) * 1980-08-29 1983-05-24 Dentsply Research & Development Corp. Visible light apparatus for curing photo-curable compositions
DE3044184A1 (en) * 1980-11-24 1982-06-16 Mutzhas Maximilian F DEVICE FOR PHOTOTHERAPEUTIC TREATMENT OF HYPERBILIRUBINAEMIA
US5036242A (en) * 1989-10-19 1991-07-30 Atlas Electric Devices Company Lamp cooling system
EP0437183B1 (en) * 1990-01-09 1994-07-27 Ciba-Geigy Ag Light diffuser for a photodynamic therapy of tumours in the oesophagus of a patient
DE4112275A1 (en) * 1991-04-15 1992-11-19 Zetterer Gerd Dipl Ing Fh Therapeutic radiation equipment using lamp as light source with control system - uses optical filter components contg. dichroitic coated colour splitter for photo-dynamic therapy suitable for tumours
IL100545A (en) * 1991-12-29 1995-03-15 Dimotech Ltd Apparatus for photodynamic therapy treatment
US5285363A (en) * 1992-07-31 1994-02-08 Hughes-Jvc Technology Corporation Heat transfer unit
GB2272278B (en) * 1992-10-23 1997-04-09 Cancer Res Campaign Tech Light source

Also Published As

Publication number Publication date
US5707401A (en) 1998-01-13
CA2144209C (en) 2001-07-31
IL108918A (en) 1997-04-15
IL108918A0 (en) 1994-06-24
DE19507980C2 (en) 2002-01-10
ZA951948B (en) 1995-11-13
GB2287652A (en) 1995-09-27
GB2287652B (en) 1997-10-15
GB9504032D0 (en) 1995-04-19
DE19507980A1 (en) 1995-09-14

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