CA2175720C - Bifurcated stent and method for the manufacture and delivery of same - Google Patents
Bifurcated stent and method for the manufacture and delivery of same Download PDFInfo
- Publication number
- CA2175720C CA2175720C CA2175720A CA2175720A CA2175720C CA 2175720 C CA2175720 C CA 2175720C CA 2175720 A CA2175720 A CA 2175720A CA 2175720 A CA2175720 A CA 2175720A CA 2175720 C CA2175720 C CA 2175720C
- Authority
- CA
- Canada
- Prior art keywords
- stent
- stent section
- section
- method defined
- bifurcated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/856—Single tubular stent with a side portal passage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/954—Instruments specially adapted for placement or removal of stents or stent-grafts for placing stents or stent-grafts in a bifurcation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/852—Two or more distinct overlapping stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2002/065—Y-shaped blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2002/065—Y-shaped blood vessels
- A61F2002/067—Y-shaped blood vessels modular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2002/828—Means for connecting a plurality of stents allowing flexibility of the whole structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91525—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91566—Adjacent bands being connected to each other connected trough to trough
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91575—Adjacent bands being connected to each other connected peak to trough
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
- A61F2210/0023—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
- A61F2210/0042—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply using a fluid, e.g. circulating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0058—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements soldered or brazed or welded
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular
Abstract
An expandable bifurcated stent comprising a proximal end and a distal end in communication with one another. The proximal end comprises a primary passageway and the distal end comprises a pair of secondary passageways. The stent is expandable from a first, contracted position to a second, expanded position upon the application of a radially outward force exerted on the stent. Each of the primary passageway and the secondary passageway being constructed of a tubular wall having a porous surface, a method for production of a bifurcated stent is also described. The method comprises the step of connecting a first stent section to a second stent section, the first stent section having an end thereof adapted for connection to an opening disposed along the length of a second stent section.
Description
BIFURCATED ST .NT AND METHOD FOR T
MANUFACTURE AND DELIVERY OF SAME
The present invention relates to a method for the manufacture of a bifurcated stent.
Stents are generally known. Indeed, the term "stent" has been used interchangeably with terms such as "intraluminal vascular graft" and "expansible prosthesis". As used throughout this specification the term "stent" is intended to have a broad meaning and encompasses any expandable prosthetic device for implantation in a body passageway (e.g. a lumen or artery).
In the past six to eight years, the use of stents has attracted an increasing amount of attention due the potential of these devices to be used, in certain cases, as an alternative to surgery. Generally, a stent is used to obtain and maintain the patency of the body passageway while maintaining the integrity of the passageway. As used in this specification, the term "body passageway" is intended to have a broad meaning and encompasses any duct (e.g. natural or iatrogenic) within the human body and can include a member selected from the group comprising: blood vessels, respiratory ducts, gastrointestinal ducts and the like.
Initial stents were self-expanding, spring-like devices which were inserted in the body passageway in a contracted state. When released, the stent would automatically expand and increase to a final diameter dependent on the size of the stent and the elasticity of the body passageway. Such stents were known in the art as the Wallstenth.
The self-expanding stents were found by some investigators to be deficient since, when deployed, they could place undue, permanent stress on the walls of the body passageway. This lead to the development of various stents which were controllably expandable at the target body passageway so that only sufficient force to maintain the patency of the body passageway was applied in expanding the stent.
Generally, in these later systems, a stent, in association with a balloon, is delivered to the target area of the body passageway by a catheter system. Once the stent has been properly located (the target area of the body passageway can be filled with a contrast medium to facilitate visualization during fluoroscopy), the balloon is expanded thereby expanding the stent so that the latter is urged in place against the body passageway. As indicated above, the amount of force applied is at least that necessary to maintain the patency of the body passageway. At this point, the balloon is deflated and withdrawn within the catheter, and subsequently removed. Ideally, the stent will remain in place and maintain the target area of the body passageway substantially free of blockage (or narrowing).
A stent which has gained some notoriety in the art is known as the Palmaz-SchatzT' Balloon Expandable Stent (hereinafter referred to as "the Palmaz-Schatz stent"). This stent is discussed in a number of patents including United States patents 4,733,665, 4,739,762, 5,102,417 and 5,316,023.
Another stent which has gained some notoriety in the art is known as Gianturco-Roubin Flex-Stent' (hereinafter referred to as "the Gianturco-Roubin stent"). This stent is discussed in a number of patents including United States patents 4,800,882, 4,907,336 and 5,041,126
MANUFACTURE AND DELIVERY OF SAME
The present invention relates to a method for the manufacture of a bifurcated stent.
Stents are generally known. Indeed, the term "stent" has been used interchangeably with terms such as "intraluminal vascular graft" and "expansible prosthesis". As used throughout this specification the term "stent" is intended to have a broad meaning and encompasses any expandable prosthetic device for implantation in a body passageway (e.g. a lumen or artery).
In the past six to eight years, the use of stents has attracted an increasing amount of attention due the potential of these devices to be used, in certain cases, as an alternative to surgery. Generally, a stent is used to obtain and maintain the patency of the body passageway while maintaining the integrity of the passageway. As used in this specification, the term "body passageway" is intended to have a broad meaning and encompasses any duct (e.g. natural or iatrogenic) within the human body and can include a member selected from the group comprising: blood vessels, respiratory ducts, gastrointestinal ducts and the like.
Initial stents were self-expanding, spring-like devices which were inserted in the body passageway in a contracted state. When released, the stent would automatically expand and increase to a final diameter dependent on the size of the stent and the elasticity of the body passageway. Such stents were known in the art as the Wallstenth.
The self-expanding stents were found by some investigators to be deficient since, when deployed, they could place undue, permanent stress on the walls of the body passageway. This lead to the development of various stents which were controllably expandable at the target body passageway so that only sufficient force to maintain the patency of the body passageway was applied in expanding the stent.
Generally, in these later systems, a stent, in association with a balloon, is delivered to the target area of the body passageway by a catheter system. Once the stent has been properly located (the target area of the body passageway can be filled with a contrast medium to facilitate visualization during fluoroscopy), the balloon is expanded thereby expanding the stent so that the latter is urged in place against the body passageway. As indicated above, the amount of force applied is at least that necessary to maintain the patency of the body passageway. At this point, the balloon is deflated and withdrawn within the catheter, and subsequently removed. Ideally, the stent will remain in place and maintain the target area of the body passageway substantially free of blockage (or narrowing).
A stent which has gained some notoriety in the art is known as the Palmaz-SchatzT' Balloon Expandable Stent (hereinafter referred to as "the Palmaz-Schatz stent"). This stent is discussed in a number of patents including United States patents 4,733,665, 4,739,762, 5,102,417 and 5,316,023.
Another stent which has gained some notoriety in the art is known as Gianturco-Roubin Flex-Stent' (hereinafter referred to as "the Gianturco-Roubin stent"). This stent is discussed in a number of patents including United States patents 4,800,882, 4,907,336 and 5,041,126
-2-Other types of stents are disclosed in the following patents:
United States patent 5,035,706 (Gianturco et al.), United States patent 5,037,392 (Hillstead), United States patent 5,147,385 (Beck et al.), United States patent 5,282,824 (Gianturco), Canadian patent 1,239,755 (Wallsten), and Canadian patent 1,245,527 (Gianturco et al.), All of the stents described in the above-identified patents share the common design of being mono-tubular and thus, are best suited to be delivered and implanted in-line in the body passageway. These known stents are inappropriate for use in a bifurcated body passageway (e.g. a body passageway comprising a parent passageway that splits into a pair of passageways). Further, these stents are inappropriate for use in a body passageway having side branches since: (i) accurate placement of the stent substantially increases the risk to the patient, (ii) the risk of passageway closure in the side branches is increased, and (iii) the side branches will be substantially inaccessible.
Indeed the Physician Guide published in support of the Palmaz-Schatz stent states on page 32I
" ... no attempt should be made following placement of a PALMAZ-SCHATZ stent to access the side branch with a
United States patent 5,035,706 (Gianturco et al.), United States patent 5,037,392 (Hillstead), United States patent 5,147,385 (Beck et al.), United States patent 5,282,824 (Gianturco), Canadian patent 1,239,755 (Wallsten), and Canadian patent 1,245,527 (Gianturco et al.), All of the stents described in the above-identified patents share the common design of being mono-tubular and thus, are best suited to be delivered and implanted in-line in the body passageway. These known stents are inappropriate for use in a bifurcated body passageway (e.g. a body passageway comprising a parent passageway that splits into a pair of passageways). Further, these stents are inappropriate for use in a body passageway having side branches since: (i) accurate placement of the stent substantially increases the risk to the patient, (ii) the risk of passageway closure in the side branches is increased, and (iii) the side branches will be substantially inaccessible.
Indeed the Physician Guide published in support of the Palmaz-Schatz stent states on page 32I
" ... no attempt should be made following placement of a PALMAZ-SCHATZ stent to access the side branch with a
-3-guide wire or a balloon, as such attempts may result in additional damage to the target vessel or the stent. Attempts to treat obstructed side branches within stented segments can result in balloon entrapment, necessitating emergency bypass surgery."
Thus, when installed, the Palmaz-Schatz stent admittedly shields side branches emanating from the target area of the body passageway effectively permanently. This can be problematic since the only way to treat blockage or other problems associated with the side branches is to perform the type of surgery which installation of the stent was intended to avoid.
This contraindication for conventional mono-tubular stents is corroborated by a number of investigators. See, for example, the following:
1. Interventional Cardiovascular Medicine: Principles and Practice (1994); Publisher: Churchill Livingstone Inc.; pages 221-223 (Ohman et al.), 487-488 (Labinaz et al.), 667-668 (Bashore et al.) and 897 (Bailey et al.), including references cited therein;
2. Gianturco-Roubin Flex-StentT"I Coronary Stent:
Physician's Guide; page 2, Paragraph 3 under WARNINGS;
3. Circulation, Vol. 83, No. 1, January 1991 (Schatz et al.); entitled "Clinical Experience With the Palmaz-
Thus, when installed, the Palmaz-Schatz stent admittedly shields side branches emanating from the target area of the body passageway effectively permanently. This can be problematic since the only way to treat blockage or other problems associated with the side branches is to perform the type of surgery which installation of the stent was intended to avoid.
This contraindication for conventional mono-tubular stents is corroborated by a number of investigators. See, for example, the following:
1. Interventional Cardiovascular Medicine: Principles and Practice (1994); Publisher: Churchill Livingstone Inc.; pages 221-223 (Ohman et al.), 487-488 (Labinaz et al.), 667-668 (Bashore et al.) and 897 (Bailey et al.), including references cited therein;
2. Gianturco-Roubin Flex-StentT"I Coronary Stent:
Physician's Guide; page 2, Paragraph 3 under WARNINGS;
3. Circulation, Vol. 83, No. 1, January 1991 (Schatz et al.); entitled "Clinical Experience With the Palmaz-
-4-Schatz Coronary Stent"; pages 148-161 at page 149;
and 4. American Heart Journal, Vol. 127, No. 2, February 1994 (Eeckhout et al.); entitled "Complications and follow-up after intracoronary stenting: Critical analysis of a 6-year single-center experience"; pages 262-272 at page 263.
Further, some investigators have attempted to install individual stents in each branch of the bifurcated body passageway. However, this approach is fraught with at least two significant problems. First, implantation of three individual stents, together with the expansive forces generated upon implantation results in subjecting the central walls of the bifurcated body passageway to undue stress which may lead to post-procedural complications. Second, since the central walls of the bifurcated body passageway are not supported by the individual stents, this area of the passageway is left substantially unprotected and susceptible to blockage.
One particular problem area with bifurcated body passageways is the occurrence of bifurcation lesions within the coronary circulation. Generally, these legions may be classified as follows:
and 4. American Heart Journal, Vol. 127, No. 2, February 1994 (Eeckhout et al.); entitled "Complications and follow-up after intracoronary stenting: Critical analysis of a 6-year single-center experience"; pages 262-272 at page 263.
Further, some investigators have attempted to install individual stents in each branch of the bifurcated body passageway. However, this approach is fraught with at least two significant problems. First, implantation of three individual stents, together with the expansive forces generated upon implantation results in subjecting the central walls of the bifurcated body passageway to undue stress which may lead to post-procedural complications. Second, since the central walls of the bifurcated body passageway are not supported by the individual stents, this area of the passageway is left substantially unprotected and susceptible to blockage.
One particular problem area with bifurcated body passageways is the occurrence of bifurcation lesions within the coronary circulation. Generally, these legions may be classified as follows:
-5-Type Characteristic A Prebranch stenosis not involving the ostium of the side branch;
B Postbranch stenosis of the parent vessel not involving the origin of the side branch;
C Stenosis encompassing the side branch but not involving the ostium;
D Stenosis involving the parent vessel and ostium of the side branch;
E Stenosis involving the ostium of the side branch only; and F Stenosis discretely involving the parent vessel and ostium of the side branch.
See Atlas of Interventional Cardiology (Popma et al.), 1994, pages 77-79, The presence of bifurcation lesions is predictive of increased procedural complications including acute vessel closure.
Detailed classification of other bifurcated body passageways is relatively undeveloped given the lack of non-surgical treatment approaches.
B Postbranch stenosis of the parent vessel not involving the origin of the side branch;
C Stenosis encompassing the side branch but not involving the ostium;
D Stenosis involving the parent vessel and ostium of the side branch;
E Stenosis involving the ostium of the side branch only; and F Stenosis discretely involving the parent vessel and ostium of the side branch.
See Atlas of Interventional Cardiology (Popma et al.), 1994, pages 77-79, The presence of bifurcation lesions is predictive of increased procedural complications including acute vessel closure.
Detailed classification of other bifurcated body passageways is relatively undeveloped given the lack of non-surgical treatment approaches.
-6-United States patent 4,994,071 (MacGregor) discloses a bifurcating stent apparatus. The particular design incorporates a series of generally parallel oriented loops interconnected by a sequence of "half-birch"
connections. The lattice structure of the illustrated stent is constructed of wire. The use of such wire is important to obtain the loop structure of the illustrated design. The use of a wire loop construction is disadvantageous since it is complicated to manufacture and the resulting stent is subject to expansion variability (e.g. variable post-expansion distortion and the like).
United States patent 5,342,387 (Summers) also discloses and illustrates a bifurcated stent design constructed of wire. This design suffers from the same disadvantages as the design described in the previous paragraph.
It would be desirable to have a reliable, expandable bifurcated stent since this would be useful in treating aneurysms, blockages and other ailments. It would be further desirable to have a practical method for producing such a stent. It would also be desirable if such a stent was relatively easy to install.
It is an object of the present invention to provide a novel expandable bifurcated stent which obviates or mitigates at least one of the above-mentioned disadvantages of the prior art.
It is another object of the present invention to provide a novel method for production an expandable bifurcated stent.
It is another object of the present invention to provide a novel method for implanting an expandable bifurcated stent.
-Accordingly, in one of its aspects, the present invention provides an expandable bifurcated stent comprising a proximal end and a distal end in
connections. The lattice structure of the illustrated stent is constructed of wire. The use of such wire is important to obtain the loop structure of the illustrated design. The use of a wire loop construction is disadvantageous since it is complicated to manufacture and the resulting stent is subject to expansion variability (e.g. variable post-expansion distortion and the like).
United States patent 5,342,387 (Summers) also discloses and illustrates a bifurcated stent design constructed of wire. This design suffers from the same disadvantages as the design described in the previous paragraph.
It would be desirable to have a reliable, expandable bifurcated stent since this would be useful in treating aneurysms, blockages and other ailments. It would be further desirable to have a practical method for producing such a stent. It would also be desirable if such a stent was relatively easy to install.
It is an object of the present invention to provide a novel expandable bifurcated stent which obviates or mitigates at least one of the above-mentioned disadvantages of the prior art.
It is another object of the present invention to provide a novel method for production an expandable bifurcated stent.
It is another object of the present invention to provide a novel method for implanting an expandable bifurcated stent.
-Accordingly, in one of its aspects, the present invention provides an expandable bifurcated stent comprising a proximal end and a distal end in
-7-communication with one another, the proximal end comprising a primary passageway and the distal end comprising a pair of secondary passageways, the stent being expandable from a first, contracted position to a second, expanded position upon the application of a radially outward force exerted on the stent, each of the primary passageway and the secondary passageway being constructed of a tubular wall having a porous surface.
In another of its aspects, the present invention provides a method for production of a bifurcated stent comprising the step of connecting a first stent section to a second stent section, the first stent section having an end thereof adapted for connection to an opening disposed along the length of a second stent section.
In yet another of its aspects, the present invention provides a method for production of a bifurcated stent comprising the steps of:
(i) connecting a first stent section to a second stent section to provide a connection portion;
(ii) provide an opening in the connection portion;
(iii) connecting a third stent section to the connection portion.
In yet another of its aspects, the present invention provides a method for production of a bifurcated stent comprising the steps of:
passing a first stent section having a first opening disposed along a length thereof through a second stent section having a second opening disposed along a length thereof, the first stent section having a diameter less than a diameter of the second stent section;
passing a leading end of the first stent section through the second opening of the second stent section; and
In another of its aspects, the present invention provides a method for production of a bifurcated stent comprising the step of connecting a first stent section to a second stent section, the first stent section having an end thereof adapted for connection to an opening disposed along the length of a second stent section.
In yet another of its aspects, the present invention provides a method for production of a bifurcated stent comprising the steps of:
(i) connecting a first stent section to a second stent section to provide a connection portion;
(ii) provide an opening in the connection portion;
(iii) connecting a third stent section to the connection portion.
In yet another of its aspects, the present invention provides a method for production of a bifurcated stent comprising the steps of:
passing a first stent section having a first opening disposed along a length thereof through a second stent section having a second opening disposed along a length thereof, the first stent section having a diameter less than a diameter of the second stent section;
passing a leading end of the first stent section through the second opening of the second stent section; and
-8-substantially aligning the first opening and the second opening with respect to one another.
In yet another of its aspects, the present invention provides a method for delivery to a target body passageway of an expandable bifurcated stent comprising a proximal end and a distal end in communication with one another, the proximal end comprising a primary passageway and the distal end comprising a pair of secondary passageways, the stent being expandable from a first, contracted position to a second, expanded position upon the application of a radially outward force exerted on the stent, each of the primary passageway and the secondary passageway being constructed of a tubular wall having a porous surface, the method comprising the steps of:
disposing the stent in the first, contracted position on a catheter;
inserting the stent and catheter within the target body passageway by catheterization of the target body passageway;
exerting a radially outward expansive force on the stent such that the stent assumes the second, expanded position and is urged against the target body passageway.
Thus, an aspect of the present invention relates to the provision of an expandable bifurcated stent constructed of a tubular wall having a porous surface. As used throughout this specification, the term "tubular wall", when used in relation to a stent, is intended to mean a substantially cylindrical tube which as been subjected to an etching (e.g. by laser, chemical or other suitable means) or similar technique to remove pre-selected portions of the cylindrical tube thereby providing a porous surface on the tube. To the knowledge of the Applicant's, an expandable bifurcated stent having such a tubular wall has heretofore been unknown.
In yet another of its aspects, the present invention provides a method for delivery to a target body passageway of an expandable bifurcated stent comprising a proximal end and a distal end in communication with one another, the proximal end comprising a primary passageway and the distal end comprising a pair of secondary passageways, the stent being expandable from a first, contracted position to a second, expanded position upon the application of a radially outward force exerted on the stent, each of the primary passageway and the secondary passageway being constructed of a tubular wall having a porous surface, the method comprising the steps of:
disposing the stent in the first, contracted position on a catheter;
inserting the stent and catheter within the target body passageway by catheterization of the target body passageway;
exerting a radially outward expansive force on the stent such that the stent assumes the second, expanded position and is urged against the target body passageway.
Thus, an aspect of the present invention relates to the provision of an expandable bifurcated stent constructed of a tubular wall having a porous surface. As used throughout this specification, the term "tubular wall", when used in relation to a stent, is intended to mean a substantially cylindrical tube which as been subjected to an etching (e.g. by laser, chemical or other suitable means) or similar technique to remove pre-selected portions of the cylindrical tube thereby providing a porous surface on the tube. To the knowledge of the Applicant's, an expandable bifurcated stent having such a tubular wall has heretofore been unknown.
-9-As used throughout this specification, the term "bifurcated stent" is intended to have a broad meaning and encompasses any stent having a primary passageway to which is connected at least two secondary passageways. Thus, trifurcated stents are encompassed herein. Further, one of the secondary passageways can be a continuation of the primary passageway with the result that the other secondary passageway is essentially a side branch to the primary passageway.
The Applicant's have also discovered that various repeating patterns in the porous surface of the tubular wall is particularly advantageous.
Generally, the repeating pattern is a polygon having a pair of side walls substantially parallel to the longitudinal axis of the stent passageway in question, a first concave-shaped wall and a second convex-shaped wall connecting the side walls. The various repeating patterns which are useful in the context of the present invention are disclosed in copending Canadian patent application numbers 2,134,997 and 2,171,047, and 2,175,722.
The present bifurcated stent may be construction from any suitable starting material. Preferably, the starting material is a thin tube of a metal or alloy (non-limiting examples include stainless steel, titanium, tantalum, nitinol, Elgiloy, NP35N and mixtures thereof) which would then have sections thereof cut or etched out to leave a repeating pattern, inter alia, such as one or more of those disclosed in copending Canadian patent application numbers 2,134,997 and 2,171,047, and 2,175,722.
The Applicant's have also discovered that various repeating patterns in the porous surface of the tubular wall is particularly advantageous.
Generally, the repeating pattern is a polygon having a pair of side walls substantially parallel to the longitudinal axis of the stent passageway in question, a first concave-shaped wall and a second convex-shaped wall connecting the side walls. The various repeating patterns which are useful in the context of the present invention are disclosed in copending Canadian patent application numbers 2,134,997 and 2,171,047, and 2,175,722.
The present bifurcated stent may be construction from any suitable starting material. Preferably, the starting material is a thin tube of a metal or alloy (non-limiting examples include stainless steel, titanium, tantalum, nitinol, Elgiloy, NP35N and mixtures thereof) which would then have sections thereof cut or etched out to leave a repeating pattern, inter alia, such as one or more of those disclosed in copending Canadian patent application numbers 2,134,997 and 2,171,047, and 2,175,722.
-10-The stent of the present invention (bifurcated or mono-tubular) can further comprise coating material thereon. The coating material can be disposed continuously or discontinuously on the surface of the stent.
Further, the coating may be disposed on the interior and/or the exterior surface(s) of the stent. The coating material can be one or more of a biologically inert material (e.g. to reduce the thrombogenicity of the stent), a medicinal composition which leaches into the wall of the body passageway after implantation (e.g. to provide anticoagulant action, to deliver a pharmaceutical to the body passageway and the like) and the like.
Preferably, the stent is coated with a biocompatible substance such as a biolized collagen/gelatin compound - see, for example, Emoto et al. in "Characterization of Rehydrated Gelatin Gels", Artificial Organs, 15(l):29-34(1991). The use of such a coating improves biocompatibility of the stent and facilitate fluid flow through and around the stent.
Embodiments of the present invention will be described with reference to the accompanying drawings wherein like numerals designate like parts and in which:
Figure 1 illustrates a side elevation of a bifurcated stent in accordance with the present invention;
Figures 2-4 illustrate a first embodiment of a method for production of a bifurcated stent;
Figure 5 illustrates a second embodiment of a method for production of a bifurcated stent;
Figures 6a and 6b illustrate a post-treatment of a bifurcated stent which has been produced according to the methods illustrated in Figures 2-5;
Further, the coating may be disposed on the interior and/or the exterior surface(s) of the stent. The coating material can be one or more of a biologically inert material (e.g. to reduce the thrombogenicity of the stent), a medicinal composition which leaches into the wall of the body passageway after implantation (e.g. to provide anticoagulant action, to deliver a pharmaceutical to the body passageway and the like) and the like.
Preferably, the stent is coated with a biocompatible substance such as a biolized collagen/gelatin compound - see, for example, Emoto et al. in "Characterization of Rehydrated Gelatin Gels", Artificial Organs, 15(l):29-34(1991). The use of such a coating improves biocompatibility of the stent and facilitate fluid flow through and around the stent.
Embodiments of the present invention will be described with reference to the accompanying drawings wherein like numerals designate like parts and in which:
Figure 1 illustrates a side elevation of a bifurcated stent in accordance with the present invention;
Figures 2-4 illustrate a first embodiment of a method for production of a bifurcated stent;
Figure 5 illustrates a second embodiment of a method for production of a bifurcated stent;
Figures 6a and 6b illustrate a post-treatment of a bifurcated stent which has been produced according to the methods illustrated in Figures 2-5;
-11-Figures 7 and 8 illustrate a third embodiment of a method for production of a bifurcated stent;
Figure 9 illustrates a post-treated bifurcated stent which has been produced according to the method illustrated in Figures 7 and 8;
Figures 10 and 11 illustrate a fourth embodiment.of a method for production of a bifurcated stent;
Figure 12 illustrates a cross-section of a bifurcated body passageway into which the a bifurcated stent produced according to the present method of manufacture is being delivered;
Figure 13 illustrates a cross-section of a bifurcated body passageway in which the bifurcated stent is positioned in a first, contracted position;
and Figure 14 illustrates a cross-section of a bifurcated body passageway in which the bifurcated stent is positioned in a second, expanded position.
With reference to Figure 1, there is illustrated a stent 10. Stent 10 comprises a proximal end 15 and a distal end 20. Proximal end 15 comprises a primary passageway 25. Distal end 20 comprises a pair of secondary passageways 30, 35. Secondary passageways 30, 35 are connected to primary passageway 25 at an intersection point 40.
As will be apparent to those of skill in the art, stent 10 incorporates the porous surface design illustrated in copending Canadian patent application number.
2;134,944. As discussed above, this design may be varied to incorporate bier designs such cats those disclosed in copending Canadian patent application numbers 2,171,047 and 2,175,722. With reference to Figures 2-4, an embodiment of the present method for the production of
Figure 9 illustrates a post-treated bifurcated stent which has been produced according to the method illustrated in Figures 7 and 8;
Figures 10 and 11 illustrate a fourth embodiment.of a method for production of a bifurcated stent;
Figure 12 illustrates a cross-section of a bifurcated body passageway into which the a bifurcated stent produced according to the present method of manufacture is being delivered;
Figure 13 illustrates a cross-section of a bifurcated body passageway in which the bifurcated stent is positioned in a first, contracted position;
and Figure 14 illustrates a cross-section of a bifurcated body passageway in which the bifurcated stent is positioned in a second, expanded position.
With reference to Figure 1, there is illustrated a stent 10. Stent 10 comprises a proximal end 15 and a distal end 20. Proximal end 15 comprises a primary passageway 25. Distal end 20 comprises a pair of secondary passageways 30, 35. Secondary passageways 30, 35 are connected to primary passageway 25 at an intersection point 40.
As will be apparent to those of skill in the art, stent 10 incorporates the porous surface design illustrated in copending Canadian patent application number.
2;134,944. As discussed above, this design may be varied to incorporate bier designs such cats those disclosed in copending Canadian patent application numbers 2,171,047 and 2,175,722. With reference to Figures 2-4, an embodiment of the present method for the production of
-12-= 2175720 a bifurcated stent is illustrated. For ease of illustration, the porous surface of the tubular wall of the stent is not illustrated.
As illustrated, a first stent section 45 comprises a cylindrical tube having a bevelled cut made adjacent one end of the cylindrical tube. Those of skill in the art will recognize that bevelled cut 50 may be incorporated into first stent section 45 during or after the production of first stent section 45. Specifically, it is possible to produce first stent section 45 having a pre-selected porous design which includes bevelled cut 50 in the computer programmable, high precision laser etching or other etching possible to produce first stent section 45 without bevelled cut 50 and thereafter use a precision jig or other means to cut first stent section 45 to produce bevelled cut 50.
Similarly, a second stent section 55 is provided and includes radial cuts 56,57 and a longitudinal cut 58. Radial cuts 56,57 and longitudinal cuts 58 may be produced in second stent section 55 in the manner discussed in the previous paragraph with respect to the production of bevelled cut 50 in first stent section 45.
Thereafter, a flap portion 51 of first stent section 45 is folded away from bevelled cut 50. Similarly, a pair of flap portions 52,53 are folded away from longitudinal cut 58 to expose an opening 54.
First stent section 45 is then lowered to cover opening 54 of second stent section 55. Flaps 52,53 are folded to overlap a portion of first stent section 45.
Flap 51 is folded to overlap a portion of second stent section 55. At this point, the flaps may be secured to the respective stent sections by any suitable means such as spot welding (e.g. by a laser or other suitable means), loops, clips and the like.
The preferred method of affixing the flaps to the respective stent section is to spot weld them.
A particular advantage of the process illustrated in Figures 2-4 is that intersection point 40 (Figure 1) of the resulting stent is reinforced by virtue of disposition of the flaps overlapping a portion of the respective stent sections.
As illustrated, a first stent section 45 comprises a cylindrical tube having a bevelled cut made adjacent one end of the cylindrical tube. Those of skill in the art will recognize that bevelled cut 50 may be incorporated into first stent section 45 during or after the production of first stent section 45. Specifically, it is possible to produce first stent section 45 having a pre-selected porous design which includes bevelled cut 50 in the computer programmable, high precision laser etching or other etching possible to produce first stent section 45 without bevelled cut 50 and thereafter use a precision jig or other means to cut first stent section 45 to produce bevelled cut 50.
Similarly, a second stent section 55 is provided and includes radial cuts 56,57 and a longitudinal cut 58. Radial cuts 56,57 and longitudinal cuts 58 may be produced in second stent section 55 in the manner discussed in the previous paragraph with respect to the production of bevelled cut 50 in first stent section 45.
Thereafter, a flap portion 51 of first stent section 45 is folded away from bevelled cut 50. Similarly, a pair of flap portions 52,53 are folded away from longitudinal cut 58 to expose an opening 54.
First stent section 45 is then lowered to cover opening 54 of second stent section 55. Flaps 52,53 are folded to overlap a portion of first stent section 45.
Flap 51 is folded to overlap a portion of second stent section 55. At this point, the flaps may be secured to the respective stent sections by any suitable means such as spot welding (e.g. by a laser or other suitable means), loops, clips and the like.
The preferred method of affixing the flaps to the respective stent section is to spot weld them.
A particular advantage of the process illustrated in Figures 2-4 is that intersection point 40 (Figure 1) of the resulting stent is reinforced by virtue of disposition of the flaps overlapping a portion of the respective stent sections.
-13-As will be apparent to those of skill in the art, in certain circumstances, it may be possible and even desirable to reduce the size of or even eliminate flap 51.
Further, in certain circumstances, it may be possible or ever desirable to trim one or both of flaps 52,53 prior to connection of first stent section 45 to second stent section 55. -With reference to Figure 5, there is illustrated another embodiment of the present method for manufacture of a bifurcated stent. In this embodiment, flap (Figures 2 and 3) is simply cut away from first stent section 45a. Further, an oval opening 54a is cut into second stent section 55a (i.e. there are no flaps affixed to second stent section 55a). Stent section 45a is then lowered on and connected to second scent section 55a. First stent section 45a and second stent section 55a may be connected to another in the manner described hereinabove with reference to Figure 2-4.
With reference to Figure 6a, there is illustrated the stent produced by the methods illustrated in Figures 2-5. During production of the stent, it is desirable to minimize the angle between first stent section 45 and second stent section 55.
Even with this effort, it is preferred that the adjacent termini of first stent section 45 and section stent section 55 are subjected to application of gentle squeezing or other sufficient force in the direction of arrows A to facilitate catheterization of the stent. The result of such post-production treatment of the stent is illustrated in Figure 6b.
With reference to Figures 7 and 8, there is illustrated yet another embodiment of the present method for manufacture of a bifurcated stent. In this embodiment, a pair of first stent sections 45b are secured or affixed to one another.
Thereafter, an apex portion 46b of the resulting construction is removed exposing an opening 54b. A second stent section 55b is then connected to opening 54b provided by the combination of first stent sections 45b. The manner of securing second stent section 55b to the periphery of opening 54b created by first stent
Further, in certain circumstances, it may be possible or ever desirable to trim one or both of flaps 52,53 prior to connection of first stent section 45 to second stent section 55. -With reference to Figure 5, there is illustrated another embodiment of the present method for manufacture of a bifurcated stent. In this embodiment, flap (Figures 2 and 3) is simply cut away from first stent section 45a. Further, an oval opening 54a is cut into second stent section 55a (i.e. there are no flaps affixed to second stent section 55a). Stent section 45a is then lowered on and connected to second scent section 55a. First stent section 45a and second stent section 55a may be connected to another in the manner described hereinabove with reference to Figure 2-4.
With reference to Figure 6a, there is illustrated the stent produced by the methods illustrated in Figures 2-5. During production of the stent, it is desirable to minimize the angle between first stent section 45 and second stent section 55.
Even with this effort, it is preferred that the adjacent termini of first stent section 45 and section stent section 55 are subjected to application of gentle squeezing or other sufficient force in the direction of arrows A to facilitate catheterization of the stent. The result of such post-production treatment of the stent is illustrated in Figure 6b.
With reference to Figures 7 and 8, there is illustrated yet another embodiment of the present method for manufacture of a bifurcated stent. In this embodiment, a pair of first stent sections 45b are secured or affixed to one another.
Thereafter, an apex portion 46b of the resulting construction is removed exposing an opening 54b. A second stent section 55b is then connected to opening 54b provided by the combination of first stent sections 45b. The manner of securing second stent section 55b to the periphery of opening 54b created by first stent
-14-sections 45b is not particularly restricted and may be effected as discussed hereinabove. As will be appreciated by those of skill in the art, it is possible and, in certain circumstances, desirable, to have one or more flaps on one or move of first stent sections 45b and second stent section 55b. Such flaps would be used in the manner discussed hereinabove in respect of Figures 2-4 to overlap a portion of the opposite stent section.
With reference to Figure 9, there is illustrated the stent produced according to the method illustrated in Figures 7 and 8 after post-treatment in the manner discussed above in respect of Figures 6a and 6b. That is, first stent sections 45b are subjected to application of gentle squeezing or other sufficient force in the direction of arrows B to facilitate catheterization of the stent.
With reference to Figures 10 and 11, there is illustrated yet another embodiment of the present method for manufacture of a bifurcated stent. In this embodiment, a first stent section 45c is provided with an opening 54c. A
second stent section 55c is provided with an opening 56c. Second stent section 55c has a diameter slightly less than that of first stent section 45c. The difference in diameter between first stent section 45c and second stent section 55c is sufficient to enable coaxial movement of the stent sections with respect to one another with causing damage to either stent section.
As illustrated by arrow C in Figure 10, the end of second stent section 55c is coaxially fed into an end of first stent section 45c. Once the leading end of second stent section 55c reaches opening 54c of first stent section 45c, it is pulled through opening 54c as illustrated by arrow D in Figure 10. Second stent section 55c is pulled through opening 54c until opening 56c is aligned with opening 54c -this is illustrated by dashed oval E in Figure 11.
When practising the method illustrated in Figures 10 and 11, care should be taken to design openings 54c and 56c so that they are in alignment when the
With reference to Figure 9, there is illustrated the stent produced according to the method illustrated in Figures 7 and 8 after post-treatment in the manner discussed above in respect of Figures 6a and 6b. That is, first stent sections 45b are subjected to application of gentle squeezing or other sufficient force in the direction of arrows B to facilitate catheterization of the stent.
With reference to Figures 10 and 11, there is illustrated yet another embodiment of the present method for manufacture of a bifurcated stent. In this embodiment, a first stent section 45c is provided with an opening 54c. A
second stent section 55c is provided with an opening 56c. Second stent section 55c has a diameter slightly less than that of first stent section 45c. The difference in diameter between first stent section 45c and second stent section 55c is sufficient to enable coaxial movement of the stent sections with respect to one another with causing damage to either stent section.
As illustrated by arrow C in Figure 10, the end of second stent section 55c is coaxially fed into an end of first stent section 45c. Once the leading end of second stent section 55c reaches opening 54c of first stent section 45c, it is pulled through opening 54c as illustrated by arrow D in Figure 10. Second stent section 55c is pulled through opening 54c until opening 56c is aligned with opening 54c -this is illustrated by dashed oval E in Figure 11.
When practising the method illustrated in Figures 10 and 11, care should be taken to design openings 54c and 56c so that they are in alignment when the
-15-trailing end of second stent section 55c is flush with the trailing end of first stent section 45c. Further, region F (Figure 11) of the resulting bifurcated stent is "double reinforced" since it contains a coaxial disposition of first stent section 45c and second stent section 55c. Accordingly, it is possible and, in some cases even desirable, to modify the design of the respective stent sections in this region so that the overall expansion and relative flexibility/rigidity of the stent in this region is commensurate with that of the remaining portion of the stent (i.e. the secondary passageways which branch off of region F in Figure 11).
While the embodiment illustrated in Figures 10 and 11 illustrates the resultant bifurcated stent having a coaxial, overlapping arrangement of stent sections flush at one end, it will be appreciated by those of skill in the art that the length of first stent section 45c or second stent section 55c may be shortened thereby minimizing the size of region F in Figure 11.
With reference to Figures 12-14 , there is illustrated a bifurcated body passageway 150 comprised of a proximal passageway 155 and a pair of distal passageways 160,165. As illustrated, bifurcated body passageway 150 comprises a Type "D" Bifurcation lesion having characteristic blockages 170,175,180.
Stent 10 is delivered to bifurcated body passageway 150 in the following manner. Initially, a pair of guidewires 185,190 are inserted into proximal passageway 155 such that guidewire 185 enters distal passageway 160 and guidewire 190 enters distal passageway 165. The manner by which the guidewires are inserted is conventional and within the purview of a person skilled in the art.
As illustrated, stent 10 is positioned in association with a pair of catheters 195,200 (for clarity, the interior of stent 10 is not shown).
Catheter 195 has associated with it a balloon 205. Catheter 200 has
While the embodiment illustrated in Figures 10 and 11 illustrates the resultant bifurcated stent having a coaxial, overlapping arrangement of stent sections flush at one end, it will be appreciated by those of skill in the art that the length of first stent section 45c or second stent section 55c may be shortened thereby minimizing the size of region F in Figure 11.
With reference to Figures 12-14 , there is illustrated a bifurcated body passageway 150 comprised of a proximal passageway 155 and a pair of distal passageways 160,165. As illustrated, bifurcated body passageway 150 comprises a Type "D" Bifurcation lesion having characteristic blockages 170,175,180.
Stent 10 is delivered to bifurcated body passageway 150 in the following manner. Initially, a pair of guidewires 185,190 are inserted into proximal passageway 155 such that guidewire 185 enters distal passageway 160 and guidewire 190 enters distal passageway 165. The manner by which the guidewires are inserted is conventional and within the purview of a person skilled in the art.
As illustrated, stent 10 is positioned in association with a pair of catheters 195,200 (for clarity, the interior of stent 10 is not shown).
Catheter 195 has associated with it a balloon 205. Catheter 200 has
-16-associated with it a balloon 210. Balloons 205,210 substantially fill primary passageway 25 of stent 10. Balloon 205 substantially fills secondary passageway 30 of stent 10. Balloon 210 substantially fills secondary passageway 35 of stent 10.
The stent/catheter/balloon combination is delivered through proximal passageway 155 with the aid of guidewires 185,190. As the stent/catheter/balloon combination approaches distal passageways 160,165, predisposition of guidewires 185,190 serves to separate secondary passageways 30,35 to be disposed in distal passageways 160,165, respectively. Thus, as illustrated in Figure 13, stent 10 is positioned in place.
Once stent 10 is in position, balloons 205,210 are expanded resulting in implantation of stent 10 in the corresponding interior surfaces of proximal passageway 155 and distal passageways 160,165. Upon implantation of stent 10, balloons 205,210 are collapsed. Thereafter, catheters 195,200 and guidewires 185,190 have been removed leaving the implanted stent 10 shown in Figure 14. As illustrated in Figure 14, blockages 170,175,180 are bulged radially outwardly in combination with the appropriate portions of proximal passageway 155 and distal passageways 160,165 resulting in a reduction in the overall blockage in bifurcated body passage 150.
It will be apparent to those of skill in the art that implantation of stent 10 can be accomplished by various other means. For example, it is contemplated that it is possible to substitute the pair of catheter/balloon combinations illustrated in Figures 12 and 13 with a single, bifurcated catheter/balloon design which mimics the design of the stent. Thus, in this modification, the balloon and guidewire would be design to mimic the
The stent/catheter/balloon combination is delivered through proximal passageway 155 with the aid of guidewires 185,190. As the stent/catheter/balloon combination approaches distal passageways 160,165, predisposition of guidewires 185,190 serves to separate secondary passageways 30,35 to be disposed in distal passageways 160,165, respectively. Thus, as illustrated in Figure 13, stent 10 is positioned in place.
Once stent 10 is in position, balloons 205,210 are expanded resulting in implantation of stent 10 in the corresponding interior surfaces of proximal passageway 155 and distal passageways 160,165. Upon implantation of stent 10, balloons 205,210 are collapsed. Thereafter, catheters 195,200 and guidewires 185,190 have been removed leaving the implanted stent 10 shown in Figure 14. As illustrated in Figure 14, blockages 170,175,180 are bulged radially outwardly in combination with the appropriate portions of proximal passageway 155 and distal passageways 160,165 resulting in a reduction in the overall blockage in bifurcated body passage 150.
It will be apparent to those of skill in the art that implantation of stent 10 can be accomplished by various other means. For example, it is contemplated that it is possible to substitute the pair of catheter/balloon combinations illustrated in Figures 12 and 13 with a single, bifurcated catheter/balloon design which mimics the design of the stent. Thus, in this modification, the balloon and guidewire would be design to mimic the
-17-bifurcated design of the stent. As further alternative, it is contemplated that the stent can be made of a suitable material which will expand when bifurcated body passageway 150 is flushed with a liquid having an elevated temperature (e.g. 150 F-160 F). Further, stent 10 can be designed to expand upon the application of mechanical forces other than those applied by a balloon/catheter. Still further, stent 10 can be designed self-expanding (e.g. by constructed stent from material such as nitinol and the like) to be implanted as described above. In this embodiment, the radially outward force exerted on the stent would be generated within the stent itself.
While this invention has been described with reference to illustrative embodiments, this description is not intended to be construed in a limiting sense. Various modifications of the illustrative embodiments, as well as other embodiments of the invention , will be apparent to persons skilled in the art upon reference to this description. It is therefore contemplated that the appended claims will cover any such modifications or embodiments.
While this invention has been described with reference to illustrative embodiments, this description is not intended to be construed in a limiting sense. Various modifications of the illustrative embodiments, as well as other embodiments of the invention , will be apparent to persons skilled in the art upon reference to this description. It is therefore contemplated that the appended claims will cover any such modifications or embodiments.
-18-
Claims (16)
1. A method for production of a bifurcated stent comprising the steps of (i) connecting a first stent section to a second stent section, the first stent section having an end thereof adapted for connection to an opening disposed along the length of the second stent section, and (ii) disposing at least one first flap portion at the end of the first stent section adapted for connection to the opening disposed along the length of the second stent section.
2. The method defined in claim 1, wherein the end of the first stent section adapted for connection is bevelled with respect to a longitudinal axis of the first stent section.
3. The method defined in any one of claims 1-2, wherein the at least one first flap portion is produced by folding from the end of the first stent section adjacent the bevelled cut.
4. The method defined in any one of claims 1-3, wherein, prior to the connecting step, the at least one first flap portion is trimmed to a reduced size.
5. The method defined in any one of claims 1-4, comprising the further step of overlapping the at least one first flap portion of the first stent section on to a portion of the second stent section.
6. The method defined in any one of claims 1-5, wherein the connecting step comprises welding the at least one first flap portion of the first stent section to the second stent section.
7. The method defined in any one of claims 1-3, wherein, prior to the connecting step, the at least one first flap portion is removed.
8. The method defined in any one of claims 1-7, comprising the further step of disposing at least one second flap portion at a periphery of the opening disposed along the length of the second stent section.
9. The method defined in any one of claims 1-7, comprising the further step of disposing a pair of second flap portions at a periphery of the opening disposed along the length of the second stent section.
10. The method defined in claim 9, wherein, prior to the connecting step, at least one of the second flap portions is trimmed to a reduced size.
11. The method defined in claim 10, comprising the further step of overlapping the at least one second flap portion of the second stent section on to a portion of the first stent section.
12. The method defined in any one of claims 8-11, wherein the connecting step comprises welding the at least one second flap portion of the second stent section to the first stent section.
13. The method defined in any one of claims 9-10, wherein, prior to the connecting step, at least one of the second flap portions is removed.
14. The method defined in claim 1, comprising the further steps of producing the second stent section by: providing a pair of third stent sections, each third stent sections having an end thereof bevelled with respect to a longitudinal axis of the third stent section; joining the pair of third stent sections in a complementary manner at each bevelled end thereof to provide a substantially V-shaped stent section; and removing an apex portion of the V-shaped stent section to define the second stent section having an opening therein.
15. The method defined in claim 14, wherein the connecting step comprises connecting the end of the first stent section to the opening defined in the V-shaped stent section.
16. The method defined in claim 1, wherein the connecting step comprises welding the first stent section to the second stent section.
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2175720A CA2175720C (en) | 1996-05-03 | 1996-05-03 | Bifurcated stent and method for the manufacture and delivery of same |
DE69729886T DE69729886T2 (en) | 1996-05-03 | 1997-05-02 | STENT WITH DISTRIBUTION AND ITS MANUFACTURING PROCESS |
AU23773/97A AU2377397A (en) | 1996-05-03 | 1997-05-02 | Bifurcated stent and method for the manufacture of same |
MYPI97001911A MY124237A (en) | 1996-05-03 | 1997-05-02 | Bifurcated stent and method for the manufacture and delivery of same |
EP97919222A EP0959811B1 (en) | 1996-05-03 | 1997-05-02 | Bifurcated stent and method for the manufacture of same |
PCT/CA1997/000294 WO1997041803A1 (en) | 1996-05-03 | 1997-05-02 | Bifurcated stent and method for the manufacture of same |
CA2253546A CA2253546C (en) | 1996-05-03 | 1997-05-02 | Bifurcated stent and method for the manufacture of same |
US08/850,742 US5906640A (en) | 1994-11-03 | 1997-05-02 | Bifurcated stent and method for the manufacture and delivery of same |
JP53936697A JP4659159B2 (en) | 1996-05-03 | 1997-05-02 | Bifurcated stent and manufacturing method thereof |
AT97919222T ATE270860T1 (en) | 1996-05-03 | 1997-05-02 | STENT WITH BRANCH AND PROCESS OF PRODUCTION THEREOF |
US09/180,146 US6811566B1 (en) | 1996-05-03 | 1997-05-02 | Bifurcated stent and method for the manufacture of same |
IDP971484A ID16864A (en) | 1996-05-03 | 1997-05-05 | VESSELS OF BRANCHES MADE AND BRANCH AND METHOD OF MAKING AND HOW TO CARRY IT |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2175720A CA2175720C (en) | 1996-05-03 | 1996-05-03 | Bifurcated stent and method for the manufacture and delivery of same |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2175720A1 CA2175720A1 (en) | 1997-11-04 |
CA2175720C true CA2175720C (en) | 2011-11-29 |
Family
ID=4158131
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2175720A Expired - Fee Related CA2175720C (en) | 1994-11-03 | 1996-05-03 | Bifurcated stent and method for the manufacture and delivery of same |
CA2253546A Expired - Fee Related CA2253546C (en) | 1996-05-03 | 1997-05-02 | Bifurcated stent and method for the manufacture of same |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2253546A Expired - Fee Related CA2253546C (en) | 1996-05-03 | 1997-05-02 | Bifurcated stent and method for the manufacture of same |
Country Status (10)
Country | Link |
---|---|
US (2) | US5906640A (en) |
EP (1) | EP0959811B1 (en) |
JP (1) | JP4659159B2 (en) |
AT (1) | ATE270860T1 (en) |
AU (1) | AU2377397A (en) |
CA (2) | CA2175720C (en) |
DE (1) | DE69729886T2 (en) |
ID (1) | ID16864A (en) |
MY (1) | MY124237A (en) |
WO (1) | WO1997041803A1 (en) |
Families Citing this family (264)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6039749A (en) | 1994-02-10 | 2000-03-21 | Endovascular Systems, Inc. | Method and apparatus for deploying non-circular stents and graftstent complexes |
CA2134997C (en) * | 1994-11-03 | 2009-06-02 | Ian M. Penn | Stent |
US6991614B2 (en) | 1995-11-07 | 2006-01-31 | Boston Scientific Scimed, Inc. | Ureteral stent for improved patient comfort |
US6017363A (en) * | 1997-09-22 | 2000-01-25 | Cordis Corporation | Bifurcated axially flexible stent |
US6258116B1 (en) * | 1996-01-26 | 2001-07-10 | Cordis Corporation | Bifurcated axially flexible stent |
US6796997B1 (en) | 1996-03-05 | 2004-09-28 | Evysio Medical Devices Ulc | Expandable stent |
EP1477133B9 (en) * | 1996-03-05 | 2007-11-21 | Evysio Medical Devices Ulc | Expandable stent |
CA2192520A1 (en) | 1996-03-05 | 1997-09-05 | Ian M. Penn | Expandable stent and method for delivery of same |
US6440165B1 (en) * | 1996-05-03 | 2002-08-27 | Medinol, Ltd. | Bifurcated stent with improved side branch aperture and method of making same |
US6251133B1 (en) | 1996-05-03 | 2001-06-26 | Medinol Ltd. | Bifurcated stent with improved side branch aperture and method of making same |
US6770092B2 (en) | 1996-05-03 | 2004-08-03 | Medinol Ltd. | Method of delivering a bifurcated stent |
US7641685B2 (en) * | 1996-05-03 | 2010-01-05 | Medinol Ltd. | System and method for delivering a bifurcated stent |
UA58485C2 (en) | 1996-05-03 | 2003-08-15 | Медінол Лтд. | Method for manufacture of bifurcated stent (variants) and bifurcated stent (variants) |
US6007573A (en) * | 1996-09-18 | 1999-12-28 | Microtherapeutics, Inc. | Intracranial stent and method of use |
US6835203B1 (en) | 1996-11-04 | 2004-12-28 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
ES2273363T3 (en) * | 1996-11-04 | 2007-05-01 | Advanced Stent Technologies, Inc. | DOUBLE EXTENSIBLE STENT. |
US6599316B2 (en) | 1996-11-04 | 2003-07-29 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
US6325826B1 (en) * | 1998-01-14 | 2001-12-04 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
US7591846B2 (en) | 1996-11-04 | 2009-09-22 | Boston Scientific Scimed, Inc. | Methods for deploying stents in bifurcations |
US8211167B2 (en) | 1999-12-06 | 2012-07-03 | Boston Scientific Scimed, Inc. | Method of using a catheter with attached flexible side sheath |
US6692483B2 (en) | 1996-11-04 | 2004-02-17 | Advanced Stent Technologies, Inc. | Catheter with attached flexible side sheath |
US7341598B2 (en) * | 1999-01-13 | 2008-03-11 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
US6682536B2 (en) | 2000-03-22 | 2004-01-27 | Advanced Stent Technologies, Inc. | Guidewire introducer sheath |
AU721415B2 (en) * | 1996-11-08 | 2000-07-06 | Converge Medical, Inc. | Percutaneous bypass graft and securing system |
US7959664B2 (en) * | 1996-12-26 | 2011-06-14 | Medinol, Ltd. | Flat process of drug coating for stents |
US5906759A (en) * | 1996-12-26 | 1999-05-25 | Medinol Ltd. | Stent forming apparatus with stent deforming blades |
US6096073A (en) * | 1997-02-25 | 2000-08-01 | Scimed Life Systems, Inc. | Method of deploying a stent at a lesion site located at a bifurcation in a parent vessel |
GB9703859D0 (en) * | 1997-02-25 | 1997-04-16 | Plante Sylvain | Expandable intravascular stent |
FR2760351B1 (en) * | 1997-03-04 | 1999-05-28 | Bernard Glatt | HELICAL STENT FORMING DEVICE AND MANUFACTURING METHOD THEREOF |
US6409755B1 (en) * | 1997-05-29 | 2002-06-25 | Scimed Life Systems, Inc. | Balloon expandable stent with a self-expanding portion |
US6070589A (en) | 1997-08-01 | 2000-06-06 | Teramed, Inc. | Methods for deploying bypass graft stents |
US6165195A (en) | 1997-08-13 | 2000-12-26 | Advanced Cardiovascylar Systems, Inc. | Stent and catheter assembly and method for treating bifurcations |
US6746476B1 (en) | 1997-09-22 | 2004-06-08 | Cordis Corporation | Bifurcated axially flexible stent |
US6254627B1 (en) | 1997-09-23 | 2001-07-03 | Diseno Y Desarrollo Medico S.A. De C.V. | Non-thrombogenic stent jacket |
CN1221222C (en) * | 1997-09-23 | 2005-10-05 | 卡洛斯·万得瓦尔德·弗雷德伯格 | Bifurcated stent with flexbile side portion |
US6071308A (en) | 1997-10-01 | 2000-06-06 | Boston Scientific Corporation | Flexible metal wire stent |
JP4097897B2 (en) * | 1998-01-14 | 2008-06-11 | アドバンスド ステント テクノロジーズ, インコーポレイテッド | Extensible stent device |
US6261241B1 (en) * | 1998-03-03 | 2001-07-17 | Senorx, Inc. | Electrosurgical biopsy device and method |
US6099497A (en) | 1998-03-05 | 2000-08-08 | Scimed Life Systems, Inc. | Dilatation and stent delivery system for bifurcation lesions |
US6290731B1 (en) | 1998-03-30 | 2001-09-18 | Cordis Corporation | Aortic graft having a precursor gasket for repairing an abdominal aortic aneurysm |
US6626938B1 (en) | 2000-11-16 | 2003-09-30 | Cordis Corporation | Stent graft having a pleated graft member |
FR2777771B1 (en) | 1998-04-27 | 2000-08-25 | Microval | TUBULAR AND FLEXIBLE VASCULAR ENDOPROSTHESIS |
US6261273B1 (en) * | 1998-05-07 | 2001-07-17 | Carlos E. Ruiz | Access system for branched vessels amd methods of use |
US6740113B2 (en) * | 1998-05-29 | 2004-05-25 | Scimed Life Systems, Inc. | Balloon expandable stent with a self-expanding portion |
US6168621B1 (en) * | 1998-05-29 | 2001-01-02 | Scimed Life Systems, Inc. | Balloon expandable stent with a self-expanding portion |
US6066169A (en) * | 1998-06-02 | 2000-05-23 | Ave Connaught | Expandable stent having articulated connecting rods |
ATE342014T1 (en) * | 1998-06-19 | 2006-11-15 | Endologix Inc | SELF-EXPANDING BRANCHING ENDOVASCULAR PROSTHESIS |
CN1183881C (en) | 1998-07-31 | 2005-01-12 | 诺维公司 | Small vessel expandable stent and method for prodn. of same |
US6143002A (en) * | 1998-08-04 | 2000-11-07 | Scimed Life Systems, Inc. | System for delivering stents to bifurcation lesions |
US6514281B1 (en) | 1998-09-04 | 2003-02-04 | Scimed Life Systems, Inc. | System for delivering bifurcation stents |
US6193744B1 (en) * | 1998-09-10 | 2001-02-27 | Scimed Life Systems, Inc. | Stent configurations |
US7662409B2 (en) | 1998-09-25 | 2010-02-16 | Gel-Del Technologies, Inc. | Protein matrix materials, devices and methods of making and using thereof |
US6187036B1 (en) | 1998-12-11 | 2001-02-13 | Endologix, Inc. | Endoluminal vascular prosthesis |
EP1146833B1 (en) * | 1998-12-11 | 2005-08-31 | Endologix, Inc. | Endoluminal vascular prosthesis |
US6733523B2 (en) * | 1998-12-11 | 2004-05-11 | Endologix, Inc. | Implantable vascular graft |
US6660030B2 (en) | 1998-12-11 | 2003-12-09 | Endologix, Inc. | Bifurcation graft deployment catheter |
US6197049B1 (en) | 1999-02-17 | 2001-03-06 | Endologix, Inc. | Articulating bifurcation graft |
US6059824A (en) * | 1998-12-23 | 2000-05-09 | Taheri; Syde A. | Mated main and collateral stent and method for treatment of arterial disease |
US7655030B2 (en) | 2003-07-18 | 2010-02-02 | Boston Scientific Scimed, Inc. | Catheter balloon systems and methods |
US8257425B2 (en) | 1999-01-13 | 2012-09-04 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
US6332892B1 (en) | 1999-03-02 | 2001-12-25 | Scimed Life Systems, Inc. | Medical device with one or more helical coils |
US6261316B1 (en) | 1999-03-11 | 2001-07-17 | Endologix, Inc. | Single puncture bifurcation graft deployment system |
US8034100B2 (en) | 1999-03-11 | 2011-10-11 | Endologix, Inc. | Graft deployment system |
EP1164968A1 (en) * | 1999-03-30 | 2002-01-02 | Angiolink Corporation | Angular vascular stent |
US6273911B1 (en) | 1999-04-22 | 2001-08-14 | Advanced Cardiovascular Systems, Inc. | Variable strength stent |
US6402779B1 (en) | 1999-07-26 | 2002-06-11 | Endomed, Inc. | Balloon-assisted intraluminal stent graft |
DE19938377A1 (en) | 1999-08-06 | 2001-03-01 | Biotronik Mess & Therapieg | Stent for vascular branching |
US6183481B1 (en) | 1999-09-22 | 2001-02-06 | Endomed Inc. | Delivery system for self-expanding stents and grafts |
US6689156B1 (en) | 1999-09-23 | 2004-02-10 | Advanced Stent Technologies, Inc. | Stent range transducers and methods of use |
US7226475B2 (en) * | 1999-11-09 | 2007-06-05 | Boston Scientific Scimed, Inc. | Stent with variable properties |
US6679910B1 (en) | 1999-11-12 | 2004-01-20 | Latin American Devices Llc | Intraluminal stent |
JP2004506479A (en) | 2000-08-23 | 2004-03-04 | エンドームド・インコーポレーテッド | Manufacturing method of custom vascular interior device |
WO2002030329A2 (en) * | 2000-10-13 | 2002-04-18 | Rex Medical, L.P. | Covered stents with side branch |
US7267685B2 (en) * | 2000-11-16 | 2007-09-11 | Cordis Corporation | Bilateral extension prosthesis and method of delivery |
US8870946B1 (en) * | 2000-12-11 | 2014-10-28 | W.L. Gore & Associates, Inc. | Method of deploying a bifurcated side-access intravascular stent graft |
US20010044650A1 (en) * | 2001-01-12 | 2001-11-22 | Simso Eric J. | Stent for in-stent restenosis |
US6695877B2 (en) | 2001-02-26 | 2004-02-24 | Scimed Life Systems | Bifurcated stent |
WO2002067816A1 (en) * | 2001-02-26 | 2002-09-06 | Scimed Life Systems, Inc. | Bifurcated stent and delivery system |
WO2002067653A2 (en) * | 2001-02-26 | 2002-09-06 | Scimed Life Systems, Inc. | Bifurcated stent and delivery system |
US6719804B2 (en) | 2001-04-02 | 2004-04-13 | Scimed Life Systems, Inc. | Medical stent and related methods |
US7232460B2 (en) * | 2001-04-25 | 2007-06-19 | Xillus, Inc. | Nanodevices, microdevices and sensors on in-vivo structures and method for the same |
US8617231B2 (en) | 2001-05-18 | 2013-12-31 | Boston Scientific Scimed, Inc. | Dual guidewire exchange catheter system |
EP1418863B1 (en) * | 2001-08-23 | 2008-11-12 | Darrell C. Gumm | Rotating stent delivery system for side branch access and protection |
US6620202B2 (en) | 2001-10-16 | 2003-09-16 | Scimed Life Systems, Inc. | Medical stent with variable coil and related methods |
US7029496B2 (en) * | 2001-11-07 | 2006-04-18 | Scimed Life Systems, Inc. | Interlocking endoluminal device |
US7014653B2 (en) * | 2001-12-20 | 2006-03-21 | Cleveland Clinic Foundation | Furcated endovascular prosthesis |
US6682537B2 (en) | 2001-12-20 | 2004-01-27 | The Cleveland Clinic Foundation | Apparatus and method for capturing a wire in a blood vessel |
US6641606B2 (en) | 2001-12-20 | 2003-11-04 | Cleveland Clinic Foundation | Delivery system and method for deploying an endovascular prosthesis |
US7147661B2 (en) | 2001-12-20 | 2006-12-12 | Boston Scientific Santa Rosa Corp. | Radially expandable stent |
US7029493B2 (en) * | 2002-01-25 | 2006-04-18 | Cordis Corporation | Stent with enhanced crossability |
US6989024B2 (en) * | 2002-02-28 | 2006-01-24 | Counter Clockwise, Inc. | Guidewire loaded stent for delivery through a catheter |
US8328877B2 (en) | 2002-03-19 | 2012-12-11 | Boston Scientific Scimed, Inc. | Stent retention element and related methods |
EP1405613B1 (en) * | 2002-10-04 | 2006-03-22 | Sorin Biomedica Cardio S.R.L. | An implant device for treating aneurisms of the abdominal aorta |
US7326242B2 (en) * | 2002-11-05 | 2008-02-05 | Boston Scientific Scimed, Inc. | Asymmetric bifurcated crown |
EP1575451B1 (en) | 2002-12-19 | 2010-05-05 | Invatec S.p.A | Endolumenal prosthesis |
US7300460B2 (en) * | 2002-12-31 | 2007-11-27 | Counter Clockwise, Inc. | Bifurcated guidewire and methods of use |
US7169177B2 (en) * | 2003-01-15 | 2007-01-30 | Boston Scientific Scimed, Inc. | Bifurcated stent |
US7367989B2 (en) * | 2003-02-27 | 2008-05-06 | Scimed Life Systems, Inc. | Rotating balloon expandable sheath bifurcation delivery |
US7314480B2 (en) * | 2003-02-27 | 2008-01-01 | Boston Scientific Scimed, Inc. | Rotating balloon expandable sheath bifurcation delivery |
US7717953B2 (en) | 2004-10-13 | 2010-05-18 | Tryton Medical, Inc. | Delivery system for placement of prosthesis at luminal OS |
US7758630B2 (en) | 2003-04-14 | 2010-07-20 | Tryton Medical, Inc. | Helical ostium support for treating vascular bifurcations |
US8109987B2 (en) * | 2003-04-14 | 2012-02-07 | Tryton Medical, Inc. | Method of treating a lumenal bifurcation |
US7731747B2 (en) * | 2003-04-14 | 2010-06-08 | Tryton Medical, Inc. | Vascular bifurcation prosthesis with multiple thin fronds |
US7972372B2 (en) * | 2003-04-14 | 2011-07-05 | Tryton Medical, Inc. | Kit for treating vascular bifurcations |
US7481834B2 (en) * | 2003-04-14 | 2009-01-27 | Tryton Medical, Inc. | Stent for placement at luminal os |
US8083791B2 (en) | 2003-04-14 | 2011-12-27 | Tryton Medical, Inc. | Method of treating a lumenal bifurcation |
US20040215220A1 (en) * | 2003-04-24 | 2004-10-28 | Dolan Mark J. | Anastomotic stent, apparatus and methods of use thereof |
US7438721B2 (en) * | 2003-04-25 | 2008-10-21 | Medtronic Vascular, Inc. | Universal modular stent graft assembly to accommodate flow to collateral branches |
US20070032852A1 (en) * | 2003-04-25 | 2007-02-08 | Medtronic Vascular, Inc. | Methods and Apparatus for Treatment of Aneurysms Adjacent to Branch Arteries |
US7105015B2 (en) * | 2003-06-17 | 2006-09-12 | Medtronic Vascular, Inc. | Method and system for treating an ostium of a side-branch vessel |
US20050033406A1 (en) * | 2003-07-15 | 2005-02-10 | Barnhart William H. | Branch vessel stent and graft |
US8784472B2 (en) * | 2003-08-15 | 2014-07-22 | Boston Scientific Scimed, Inc. | Clutch driven stent delivery system |
US7628806B2 (en) * | 2003-08-20 | 2009-12-08 | Boston Scientific Scimed, Inc. | Stent with improved resistance to migration |
US8298280B2 (en) | 2003-08-21 | 2012-10-30 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
WO2005034852A2 (en) | 2003-08-26 | 2005-04-21 | Gel-Del Technologies, Inc. | Protein biomaterials and biocoacervates and methods of making and using thereof |
EP1673038B1 (en) | 2003-10-10 | 2008-04-23 | William A. Cook Australia Pty. Ltd. | Fenestrated stent grafts |
US9278015B2 (en) * | 2003-10-16 | 2016-03-08 | Minvasys | Catheter system for stenting and drug treatment of bifurcated vessels |
US7641684B2 (en) * | 2003-10-16 | 2010-01-05 | Minvasys, Sa | Catheter system for stenting bifurcated vessels |
US7344557B2 (en) | 2003-11-12 | 2008-03-18 | Advanced Stent Technologies, Inc. | Catheter balloon systems and methods |
US7090694B1 (en) | 2003-11-19 | 2006-08-15 | Advanced Cardiovascular Systems, Inc. | Portal design for stent for treating bifurcated vessels |
EP1691746B1 (en) | 2003-12-08 | 2015-05-27 | Gel-Del Technologies, Inc. | Mucoadhesive drug delivery devices and methods of making and using thereof |
US7686841B2 (en) * | 2003-12-29 | 2010-03-30 | Boston Scientific Scimed, Inc. | Rotating balloon expandable sheath bifurcation delivery system |
US7922753B2 (en) | 2004-01-13 | 2011-04-12 | Boston Scientific Scimed, Inc. | Bifurcated stent delivery system |
US8012192B2 (en) * | 2004-02-18 | 2011-09-06 | Boston Scientific Scimed, Inc. | Multi-stent delivery system |
US7225518B2 (en) * | 2004-02-23 | 2007-06-05 | Boston Scientific Scimed, Inc. | Apparatus for crimping a stent assembly |
US7922740B2 (en) | 2004-02-24 | 2011-04-12 | Boston Scientific Scimed, Inc. | Rotatable catheter assembly |
US7744619B2 (en) * | 2004-02-24 | 2010-06-29 | Boston Scientific Scimed, Inc. | Rotatable catheter assembly |
US8007528B2 (en) * | 2004-03-17 | 2011-08-30 | Boston Scientific Scimed, Inc. | Bifurcated stent |
EP1789126A4 (en) * | 2004-05-21 | 2008-03-12 | Minvasys Sa | Guidewire separator device and method of use |
US8617234B2 (en) | 2004-05-25 | 2013-12-31 | Covidien Lp | Flexible vascular occluding device |
EP2419048A4 (en) | 2004-05-25 | 2014-04-09 | Covidien Lp | Vascular stenting for aneurysms |
US8623067B2 (en) | 2004-05-25 | 2014-01-07 | Covidien Lp | Methods and apparatus for luminal stenting |
US20060206200A1 (en) | 2004-05-25 | 2006-09-14 | Chestnut Medical Technologies, Inc. | Flexible vascular occluding device |
WO2005115118A2 (en) | 2004-05-25 | 2005-12-08 | Chestnut Medical Technologies, Inc. | Flexible vascular occluding device |
US8267985B2 (en) * | 2005-05-25 | 2012-09-18 | Tyco Healthcare Group Lp | System and method for delivering and deploying an occluding device within a vessel |
JP5054524B2 (en) * | 2004-06-08 | 2012-10-24 | アドバンスド ステント テクノロジーズ, インコーポレイテッド | Stent with protruding branch for branch pipe |
US20050273149A1 (en) * | 2004-06-08 | 2005-12-08 | Tran Thomas T | Bifurcated stent delivery system |
US20060064064A1 (en) * | 2004-09-17 | 2006-03-23 | Jang G D | Two-step/dual-diameter balloon angioplasty catheter for bifurcation and side-branch vascular anatomy |
US9149355B2 (en) | 2004-09-21 | 2015-10-06 | Cook Medical Technologies Llc | Side branch stent graft |
US7196014B2 (en) * | 2004-11-08 | 2007-03-27 | International Business Machines Corporation | System and method for plasma induced modification and improvement of critical dimension uniformity |
US9427340B2 (en) * | 2004-12-14 | 2016-08-30 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
WO2006065644A1 (en) * | 2004-12-17 | 2006-06-22 | William A. Cook Australia Pty. Ltd. | Stented side branch graft |
US20080188803A1 (en) * | 2005-02-03 | 2008-08-07 | Jang G David | Triple-profile balloon catheter |
US7828837B2 (en) * | 2005-02-17 | 2010-11-09 | Khoury Medical Devices, LLC. | Vascular endograft |
US9597209B2 (en) | 2005-02-17 | 2017-03-21 | Khoury Medical Devices, Llc | Vascular endograft |
US7947207B2 (en) | 2005-04-12 | 2011-05-24 | Abbott Cardiovascular Systems Inc. | Method for retaining a vascular stent on a catheter |
US7763198B2 (en) | 2005-04-12 | 2010-07-27 | Abbott Cardiovascular Systems Inc. | Method for retaining a vascular stent on a catheter |
CA2604081C (en) * | 2005-05-25 | 2013-11-26 | Chestnut Medical Technologies, Inc. | System and method for delivering and deploying a self-expanding device within a vessel |
US8273101B2 (en) * | 2005-05-25 | 2012-09-25 | Tyco Healthcare Group Lp | System and method for delivering and deploying an occluding device within a vessel |
US8317855B2 (en) | 2005-05-26 | 2012-11-27 | Boston Scientific Scimed, Inc. | Crimpable and expandable side branch cell |
US8480728B2 (en) | 2005-05-26 | 2013-07-09 | Boston Scientific Scimed, Inc. | Stent side branch deployment initiation geometry |
WO2006130755A2 (en) * | 2005-06-01 | 2006-12-07 | William A. Cook Australia Pty. Ltd. | Side branch stent graft |
US20070050016A1 (en) * | 2005-08-29 | 2007-03-01 | Boston Scientific Scimed, Inc. | Stent with expanding side branch geometry |
US7955374B2 (en) * | 2005-09-02 | 2011-06-07 | Medtronic Vascular, Inc. | Modular branch vessel stent-graft assembly |
US7731741B2 (en) * | 2005-09-08 | 2010-06-08 | Boston Scientific Scimed, Inc. | Inflatable bifurcation stent |
US8043366B2 (en) | 2005-09-08 | 2011-10-25 | Boston Scientific Scimed, Inc. | Overlapping stent |
US8038706B2 (en) * | 2005-09-08 | 2011-10-18 | Boston Scientific Scimed, Inc. | Crown stent assembly |
US20070106375A1 (en) * | 2005-11-07 | 2007-05-10 | Carlos Vonderwalde | Bifurcated stent assembly |
US20070112418A1 (en) * | 2005-11-14 | 2007-05-17 | Boston Scientific Scimed, Inc. | Stent with spiral side-branch support designs |
US20070123970A1 (en) * | 2005-11-29 | 2007-05-31 | Boston Scientific Scimed, Inc. | Bifurcation stent with overlapping crimped struts |
US8343211B2 (en) | 2005-12-14 | 2013-01-01 | Boston Scientific Scimed, Inc. | Connectors for bifurcated stent |
US8435284B2 (en) | 2005-12-14 | 2013-05-07 | Boston Scientific Scimed, Inc. | Telescoping bifurcated stent |
US20070142904A1 (en) * | 2005-12-20 | 2007-06-21 | Boston Scientific Scimed, Inc. | Bifurcated stent with multiple locations for side branch access |
US7540881B2 (en) * | 2005-12-22 | 2009-06-02 | Boston Scientific Scimed, Inc. | Bifurcation stent pattern |
US20070203563A1 (en) * | 2006-02-13 | 2007-08-30 | Stephen Hebert | System for delivering a stent |
US8821561B2 (en) | 2006-02-22 | 2014-09-02 | Boston Scientific Scimed, Inc. | Marker arrangement for bifurcation catheter |
US8152833B2 (en) | 2006-02-22 | 2012-04-10 | Tyco Healthcare Group Lp | Embolic protection systems having radiopaque filter mesh |
US7833264B2 (en) | 2006-03-06 | 2010-11-16 | Boston Scientific Scimed, Inc. | Bifurcated stent |
US20070208419A1 (en) * | 2006-03-06 | 2007-09-06 | Boston Scientific Scimed, Inc. | Bifurcation stent with uniform side branch projection |
US20070208411A1 (en) * | 2006-03-06 | 2007-09-06 | Boston Scientific Scimed, Inc. | Bifurcated stent with surface area gradient |
US20070208414A1 (en) * | 2006-03-06 | 2007-09-06 | Shawn Sorenson | Tapered strength rings on a bifurcated stent petal |
US20070208415A1 (en) * | 2006-03-06 | 2007-09-06 | Kevin Grotheim | Bifurcated stent with controlled drug delivery |
US8298278B2 (en) | 2006-03-07 | 2012-10-30 | Boston Scientific Scimed, Inc. | Bifurcated stent with improvement securement |
US8167929B2 (en) | 2006-03-09 | 2012-05-01 | Abbott Laboratories | System and method for delivering a stent to a bifurcated vessel |
US20070270933A1 (en) * | 2006-03-09 | 2007-11-22 | Abbott Laboratories | Stent having contoured proximal end |
US8828077B2 (en) | 2006-03-15 | 2014-09-09 | Medinol Ltd. | Flat process of preparing drug eluting stents |
US20070225798A1 (en) * | 2006-03-23 | 2007-09-27 | Daniel Gregorich | Side branch stent |
US8043358B2 (en) * | 2006-03-29 | 2011-10-25 | Boston Scientific Scimed, Inc. | Stent with overlap and high extension |
US8348991B2 (en) * | 2006-03-29 | 2013-01-08 | Boston Scientific Scimed, Inc. | Stent with overlap and high expansion |
EP2004101A2 (en) * | 2006-04-07 | 2008-12-24 | Penumbra, Inc. | Aneurysm occlusion system and method |
US20070260304A1 (en) * | 2006-05-02 | 2007-11-08 | Daniel Gregorich | Bifurcated stent with minimally circumferentially projected side branch |
US7922758B2 (en) | 2006-06-23 | 2011-04-12 | Boston Scientific Scimed, Inc. | Nesting twisting hinge points in a bifurcated petal geometry |
US8882826B2 (en) | 2006-08-22 | 2014-11-11 | Abbott Cardiovascular Systems Inc. | Intravascular stent |
US8834554B2 (en) | 2006-08-22 | 2014-09-16 | Abbott Cardiovascular Systems Inc. | Intravascular stent |
US8216267B2 (en) | 2006-09-12 | 2012-07-10 | Boston Scientific Scimed, Inc. | Multilayer balloon for bifurcated stent delivery and methods of making and using the same |
US7951191B2 (en) | 2006-10-10 | 2011-05-31 | Boston Scientific Scimed, Inc. | Bifurcated stent with entire circumferential petal |
US20080097578A1 (en) * | 2006-10-20 | 2008-04-24 | Medtronic Vascular, Inc. | Extender Cuff for Branch Vessel |
US8206429B2 (en) | 2006-11-02 | 2012-06-26 | Boston Scientific Scimed, Inc. | Adjustable bifurcation catheter incorporating electroactive polymer and methods of making and using the same |
US7842082B2 (en) | 2006-11-16 | 2010-11-30 | Boston Scientific Scimed, Inc. | Bifurcated stent |
US8523931B2 (en) | 2007-01-12 | 2013-09-03 | Endologix, Inc. | Dual concentric guidewire and methods of bifurcated graft deployment |
US7959668B2 (en) | 2007-01-16 | 2011-06-14 | Boston Scientific Scimed, Inc. | Bifurcated stent |
US20080177370A1 (en) * | 2007-01-22 | 2008-07-24 | Adam Stys | Device and method for supporting a side branch of a vessel |
US20080177367A1 (en) * | 2007-01-22 | 2008-07-24 | Adam Stys | Treatment device for treating a side branch of a vessel and method for positioning a stent in a side branch |
DE102007006844B4 (en) | 2007-02-12 | 2014-06-12 | Bioregeneration Gmbh | Elongated hollow body for replacement of a venous blood vessel and method and mold for producing a crystalline cellulose comprising elongated hollow body |
US20080255654A1 (en) * | 2007-03-22 | 2008-10-16 | Bay Street Medical | System for delivering a stent |
US8118861B2 (en) | 2007-03-28 | 2012-02-21 | Boston Scientific Scimed, Inc. | Bifurcation stent and balloon assemblies |
US8647376B2 (en) | 2007-03-30 | 2014-02-11 | Boston Scientific Scimed, Inc. | Balloon fold design for deployment of bifurcated stent petal architecture |
US9144508B2 (en) * | 2007-07-19 | 2015-09-29 | Back Bay Medical Inc. | Radially expandable stent |
US8486134B2 (en) | 2007-08-01 | 2013-07-16 | Boston Scientific Scimed, Inc. | Bifurcation treatment system and methods |
US7959669B2 (en) | 2007-09-12 | 2011-06-14 | Boston Scientific Scimed, Inc. | Bifurcated stent with open ended side branch support |
US7833266B2 (en) | 2007-11-28 | 2010-11-16 | Boston Scientific Scimed, Inc. | Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment |
US8277501B2 (en) * | 2007-12-21 | 2012-10-02 | Boston Scientific Scimed, Inc. | Bi-stable bifurcated stent petal geometry |
WO2009086483A2 (en) | 2007-12-26 | 2009-07-09 | Gel-Del Technologies, Inc. | Biocompatible protein particles, particle devices and methods thereof |
WO2009088953A2 (en) | 2007-12-31 | 2009-07-16 | Boston Scientific Scimed Inc. | Bifurcation stent delivery system and methods |
EP3964243A1 (en) * | 2008-01-28 | 2022-03-09 | Implantica Patent Ltd | Blood clot removal device, system, and method |
US8221494B2 (en) | 2008-02-22 | 2012-07-17 | Endologix, Inc. | Apparatus and method of placement of a graft or graft system |
US20090240318A1 (en) * | 2008-03-19 | 2009-09-24 | Boston Scientific Scimed, Inc. | Stent expansion column, strut and connector slit design |
US8236040B2 (en) | 2008-04-11 | 2012-08-07 | Endologix, Inc. | Bifurcated graft deployment systems and methods |
WO2009140437A1 (en) | 2008-05-13 | 2009-11-19 | Nfocus Neuromedical, Inc. | Braid implant delivery systems |
US8333003B2 (en) * | 2008-05-19 | 2012-12-18 | Boston Scientific Scimed, Inc. | Bifurcation stent crimping systems and methods |
US8932340B2 (en) | 2008-05-29 | 2015-01-13 | Boston Scientific Scimed, Inc. | Bifurcated stent and delivery system |
US8377108B2 (en) | 2008-06-02 | 2013-02-19 | Boston Scientific Scimed, Inc. | Staggered two balloon bifurcation catheter assembly and methods |
US8827954B2 (en) | 2008-06-05 | 2014-09-09 | Boston Scientific Scimed, Inc. | Deflatable bifurcated device |
WO2009149405A1 (en) | 2008-06-05 | 2009-12-10 | Boston Scientific Scimed, Inc. | Balloon bifurcated lumen treatment |
EP2293838B1 (en) | 2008-07-01 | 2012-08-08 | Endologix, Inc. | Catheter system |
US8133199B2 (en) | 2008-08-27 | 2012-03-13 | Boston Scientific Scimed, Inc. | Electroactive polymer activation system for a medical device |
US8828071B2 (en) | 2008-09-25 | 2014-09-09 | Advanced Bifurcation Systems, Inc. | Methods and systems for ostial stenting of a bifurcation |
US8821562B2 (en) | 2008-09-25 | 2014-09-02 | Advanced Bifurcation Systems, Inc. | Partially crimped stent |
WO2010036982A1 (en) | 2008-09-25 | 2010-04-01 | Henry Bourang | Partially crimped stent |
US11298252B2 (en) | 2008-09-25 | 2022-04-12 | Advanced Bifurcation Systems Inc. | Stent alignment during treatment of a bifurcation |
US9587249B2 (en) | 2008-10-27 | 2017-03-07 | Baxalta GmbH | Models of thrombotic thrombocytopenic purpura and methods of use thereof |
US20100121247A1 (en) * | 2008-11-13 | 2010-05-13 | Chen Yang | Dialysis Graft with Thromboses Prevention Arrangement |
WO2010057177A2 (en) | 2008-11-17 | 2010-05-20 | Gel-Del Technologies, Inc. | Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof |
EP2429452B1 (en) | 2009-04-28 | 2020-01-15 | Endologix, Inc. | Endoluminal prosthesis system |
WO2010127305A2 (en) | 2009-05-01 | 2010-11-04 | Endologix, Inc. | Percutaneous method and device to treat dissections |
US10772717B2 (en) | 2009-05-01 | 2020-09-15 | Endologix, Inc. | Percutaneous method and device to treat dissections |
US8366763B2 (en) | 2009-07-02 | 2013-02-05 | Tryton Medical, Inc. | Ostium support for treating vascular bifurcations |
US8491646B2 (en) | 2009-07-15 | 2013-07-23 | Endologix, Inc. | Stent graft |
EP2459127B1 (en) | 2009-07-27 | 2015-09-23 | Endologix, Inc. | Stent graft |
AU2010201067B1 (en) * | 2010-03-19 | 2011-06-09 | Cook Incorporated | Thoracic stent graft |
EP2549951B1 (en) | 2010-03-24 | 2017-05-10 | Advanced Bifurcation Systems, Inc. | Stent alignment during treatment of a bifurcation |
CN103037815B (en) | 2010-03-24 | 2015-05-13 | 高级分支系统股份有限公司 | Methods and systems for treating a bifurcation with provisional side branch stenting |
CN109363807B (en) | 2010-03-24 | 2021-04-02 | 高级分支系统股份有限公司 | System and method for treating a bifurcation |
US9402754B2 (en) | 2010-05-18 | 2016-08-02 | Abbott Cardiovascular Systems, Inc. | Expandable endoprostheses, systems, and methods for treating a bifurcated lumen |
EP2635241B1 (en) | 2010-11-02 | 2019-02-20 | Endologix, Inc. | Apparatus for placement of a graft or graft system |
US9393100B2 (en) | 2010-11-17 | 2016-07-19 | Endologix, Inc. | Devices and methods to treat vascular dissections |
WO2012071542A2 (en) | 2010-11-24 | 2012-05-31 | Tryton Medical, Inc. | Support for treating vascular bifurcations |
EP3777780A1 (en) | 2011-02-08 | 2021-02-17 | Advanced Bifurcation Systems Inc. | System for treating a bifurcation with a fully crimped stent |
CA2826760A1 (en) | 2011-02-08 | 2012-08-16 | Advanced Bifurcation Systems, Inc. | Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use |
US8808350B2 (en) | 2011-03-01 | 2014-08-19 | Endologix, Inc. | Catheter system and methods of using same |
CA2845243C (en) | 2011-08-19 | 2020-07-14 | Khalid Al-Saadon | Stent system and deployment apparatus for bifurcated lesion |
WO2013162724A1 (en) | 2012-04-26 | 2013-10-31 | Tryton Medical, Inc. | Support for treating vascular bifurcations |
CA3081285C (en) | 2012-05-14 | 2022-05-31 | C.R. Bard, Inc. | Uniformly expandable stent |
US9155647B2 (en) | 2012-07-18 | 2015-10-13 | Covidien Lp | Methods and apparatus for luminal stenting |
EP2884949B1 (en) * | 2012-08-20 | 2018-02-21 | Al-saadon, Khalid | Bifurcated dual-balloon catheter system for bifurcated vessels |
KR101231197B1 (en) * | 2012-09-20 | 2013-02-07 | 썬텍 주식회사 | Polymeric stent |
US9301831B2 (en) | 2012-10-30 | 2016-04-05 | Covidien Lp | Methods for attaining a predetermined porosity of a vascular device |
US9452070B2 (en) | 2012-10-31 | 2016-09-27 | Covidien Lp | Methods and systems for increasing a density of a region of a vascular device |
US9943427B2 (en) | 2012-11-06 | 2018-04-17 | Covidien Lp | Shaped occluding devices and methods of using the same |
US9157174B2 (en) | 2013-02-05 | 2015-10-13 | Covidien Lp | Vascular device for aneurysm treatment and providing blood flow into a perforator vessel |
USD723165S1 (en) | 2013-03-12 | 2015-02-24 | C. R. Bard, Inc. | Stent |
AU2014228815B2 (en) | 2013-03-15 | 2019-04-18 | The Regents Of The University Of California | Peptides having reduced toxicity that stimulate cholesterol efflux |
US10034784B2 (en) * | 2013-04-17 | 2018-07-31 | Gilbert H. L. Tang | Heart valve and endovascular graft components and method for delivery |
JP6128689B2 (en) * | 2013-11-29 | 2017-05-17 | 弘志 岩村 | Artificial blood vessel |
US9468545B2 (en) | 2014-04-04 | 2016-10-18 | W. L. Gore & Associates, Inc. | Bifurcated graft device |
US20160000985A1 (en) * | 2014-07-02 | 2016-01-07 | Abbott Cardiovascular Systems Inc. | Extravascular devices supporting an arteriovenous fistula |
US10959826B2 (en) | 2014-10-16 | 2021-03-30 | Cook Medical Technology LLC | Support structure for scalloped grafts |
US10179057B2 (en) * | 2015-05-28 | 2019-01-15 | George Kramer | Tracheobronchial Y-stents, delivery catheters and delivery apparatus, and methods for delivering bronchial Y-stents |
JP2018524025A (en) | 2015-06-30 | 2018-08-30 | エンドロジックス、インク | Lock assembly for coupling guidewire to delivery system |
US10130465B2 (en) * | 2016-02-23 | 2018-11-20 | Abbott Cardiovascular Systems Inc. | Bifurcated tubular graft for treating tricuspid regurgitation |
US10772719B2 (en) * | 2017-02-14 | 2020-09-15 | Cook Medical Technologies Llc | Method of making a contoured internal limb for a prosthesis and prosthesis with a contoured internal limb |
US20200016382A1 (en) * | 2017-04-28 | 2020-01-16 | S&G Biotech, Inc. | Drainage catheter |
CN113238471B (en) * | 2021-05-20 | 2023-11-17 | 中国科学技术大学 | Rapid preparation method of bifurcated micro-pipeline |
DE102021132725A1 (en) * | 2021-12-10 | 2023-06-15 | Phenox Gmbh | Implant for the treatment of aneurysms in the area of bifurcations |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2479578A (en) * | 1943-09-25 | 1949-08-23 | Babcock & Wilcox Co | Tubular structure |
US3155095A (en) * | 1961-02-07 | 1964-11-03 | Adolph M Brown | Anastomosis method and means |
SE397769B (en) * | 1974-11-04 | 1977-11-21 | Gambro Ab | INITIATIVE ELEMENTS FOR USE IN VEHICLE SURGERY AND METHODS OF PRODUCING SUCCESSFUL |
CA1322628C (en) * | 1988-10-04 | 1993-10-05 | Richard A. Schatz | Expandable intraluminal graft |
US4994071A (en) * | 1989-05-22 | 1991-02-19 | Cordis Corporation | Bifurcating stent apparatus and method |
US5360443A (en) * | 1990-06-11 | 1994-11-01 | Barone Hector D | Aortic graft for repairing an abdominal aortic aneurysm |
CA2087132A1 (en) * | 1992-01-31 | 1993-08-01 | Michael S. Williams | Stent capable of attachment within a body lumen |
US5342387A (en) * | 1992-06-18 | 1994-08-30 | American Biomed, Inc. | Artificial support for a blood vessel |
US5639278A (en) * | 1993-10-21 | 1997-06-17 | Corvita Corporation | Expandable supportive bifurcated endoluminal grafts |
US5609627A (en) * | 1994-02-09 | 1997-03-11 | Boston Scientific Technology, Inc. | Method for delivering a bifurcated endoluminal prosthesis |
US5609605A (en) * | 1994-08-25 | 1997-03-11 | Ethicon, Inc. | Combination arterial stent |
US5653743A (en) * | 1994-09-09 | 1997-08-05 | Martin; Eric C. | Hypogastric artery bifurcation graft and method of implantation |
JP2911763B2 (en) * | 1994-10-27 | 1999-06-23 | 三桜子 布川 | Artificial blood vessel |
US5683449A (en) * | 1995-02-24 | 1997-11-04 | Marcade; Jean Paul | Modular bifurcated intraluminal grafts and methods for delivering and assembling same |
CA2171896C (en) * | 1995-03-17 | 2007-05-15 | Scott C. Anderson | Multi-anchor stent |
US5709713A (en) * | 1995-03-31 | 1998-01-20 | Cardiovascular Concepts, Inc. | Radially expansible vascular prosthesis having reversible and other locking structures |
FR2733682B1 (en) * | 1995-05-04 | 1997-10-31 | Dibie Alain | ENDOPROSTHESIS FOR THE TREATMENT OF STENOSIS ON BIFURCATIONS OF BLOOD VESSELS AND LAYING EQUIPMENT THEREFOR |
US5669924A (en) * | 1995-10-26 | 1997-09-23 | Shaknovich; Alexander | Y-shuttle stent assembly for bifurcating vessels and method of using the same |
UA58485C2 (en) * | 1996-05-03 | 2003-08-15 | Медінол Лтд. | Method for manufacture of bifurcated stent (variants) and bifurcated stent (variants) |
US5676697A (en) * | 1996-07-29 | 1997-10-14 | Cardiovascular Dynamics, Inc. | Two-piece, bifurcated intraluminal graft for repair of aneurysm |
US5728150A (en) * | 1996-07-29 | 1998-03-17 | Cardiovascular Dynamics, Inc. | Expandable microporous prosthesis |
US6086611A (en) * | 1997-09-25 | 2000-07-11 | Ave Connaught | Bifurcated stent |
US5893887A (en) * | 1997-10-14 | 1999-04-13 | Iowa-India Investments Company Limited | Stent for positioning at junction of bifurcated blood vessel and method of making |
-
1996
- 1996-05-03 CA CA2175720A patent/CA2175720C/en not_active Expired - Fee Related
-
1997
- 1997-05-02 EP EP97919222A patent/EP0959811B1/en not_active Expired - Lifetime
- 1997-05-02 JP JP53936697A patent/JP4659159B2/en not_active Expired - Fee Related
- 1997-05-02 US US08/850,742 patent/US5906640A/en not_active Expired - Lifetime
- 1997-05-02 MY MYPI97001911A patent/MY124237A/en unknown
- 1997-05-02 US US09/180,146 patent/US6811566B1/en not_active Expired - Fee Related
- 1997-05-02 WO PCT/CA1997/000294 patent/WO1997041803A1/en active IP Right Grant
- 1997-05-02 AT AT97919222T patent/ATE270860T1/en not_active IP Right Cessation
- 1997-05-02 AU AU23773/97A patent/AU2377397A/en not_active Abandoned
- 1997-05-02 DE DE69729886T patent/DE69729886T2/en not_active Expired - Lifetime
- 1997-05-02 CA CA2253546A patent/CA2253546C/en not_active Expired - Fee Related
- 1997-05-05 ID IDP971484A patent/ID16864A/en unknown
Also Published As
Publication number | Publication date |
---|---|
US5906640A (en) | 1999-05-25 |
US6811566B1 (en) | 2004-11-02 |
ATE270860T1 (en) | 2004-07-15 |
CA2253546C (en) | 2011-06-28 |
JP2001501496A (en) | 2001-02-06 |
DE69729886D1 (en) | 2004-08-19 |
ID16864A (en) | 1997-11-20 |
CA2175720A1 (en) | 1997-11-04 |
DE69729886T2 (en) | 2005-08-25 |
MY124237A (en) | 2006-06-30 |
EP0959811B1 (en) | 2004-07-14 |
CA2253546A1 (en) | 1997-11-13 |
AU2377397A (en) | 1997-11-26 |
WO1997041803A1 (en) | 1997-11-13 |
EP0959811A1 (en) | 1999-12-01 |
JP4659159B2 (en) | 2011-03-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2175720C (en) | Bifurcated stent and method for the manufacture and delivery of same | |
US6033435A (en) | Bifurcated stent and method for the manufacture and delivery of same | |
US6099560A (en) | Expandable bifurcated stent and method for delivery of same | |
JP3215807B2 (en) | Expandable stent | |
US6436133B1 (en) | Expandable graft | |
EP1342455B1 (en) | Expandable supportive branched endoluminal grafts | |
US6238409B1 (en) | Articulated expandable intraluminal stent | |
JP2009507561A (en) | Crown stent assembly | |
US7824438B2 (en) | Method for placement of a stent assembly in a bifurcated vessel | |
US20090259299A1 (en) | Side Branch Stent Having a Proximal Flexible Material Section | |
US8470017B2 (en) | Balloon for use in placing stents in bifurcated vessels | |
US9186265B2 (en) | Implantable medical device having a means for positioning it at the precise site of a branching of a blood vessel such as a coronary artery | |
AU762447B2 (en) | Bifurcated stent delivery system and method of use | |
AU769241B2 (en) | Bifurcated stent and method for the manufacture of same | |
AU782512B2 (en) | Expandable stent and method for delivery of same | |
MXPA97003222A (en) | Expandable bifurced stent and method to paramolate mi |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20140505 |