CA2185266A1 - Uterine endometrial tissue sample brush - Google Patents
Uterine endometrial tissue sample brushInfo
- Publication number
- CA2185266A1 CA2185266A1 CA002185266A CA2185266A CA2185266A1 CA 2185266 A1 CA2185266 A1 CA 2185266A1 CA 002185266 A CA002185266 A CA 002185266A CA 2185266 A CA2185266 A CA 2185266A CA 2185266 A1 CA2185266 A1 CA 2185266A1
- Authority
- CA
- Canada
- Prior art keywords
- brush
- core
- bristles
- abilities
- brush member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0291—Instruments for taking cell samples or for biopsy for uterus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B2010/0216—Sampling brushes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
A uterine endometrial tissue sample brush includes a flexible core having a distal core end and a cylindrical brush member carried adjacent the distal core end. The core is formed from a spirally wrapped pair of wires and includes an atraumatic tip. The brush member is about 3 to 5 cm long and has a free outside diameter, preferably about 5.08 to 7.62 mm (0.2 to 0.3 in.), suited to maintain patient comfort yet comprehensively contact the undilated uterine canal. The brush member includes a plurality of resilient bristles axially spaced about 0.5 .to 1.5 mm apart. The bristles have a stiffness equivalent to that possessed by nylon-6,12 at a diameter of about 0.076 to 0.152 mm (0.003 to 0.006 in.). This stiffness is critical and unexpectedly gives the brush good exfoliating and collecting abilities simultaneously, in contrast to prior devices which may possess either good exfoliating or good collecting abilities, but not both abilities at the same time. The bristles are preferably composed of nylon-6,12 of about 0.127 mm (0.005 in.) diameter, and are retained between the pair of wires so that they are spirally arrayed. The brush also preferably includes a flexible sheath adapted to slidably receive the core and brush member therein, to prevent the collection of undesired exocervical or vaginal fluid or material during introduction or removal of the brush. The brush especially useful for routinely and repeatedly collecting samples for cancer screening or for monitoring ongoing estrogen replacement therapy.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/527,838 US5713369A (en) | 1995-09-13 | 1995-09-13 | Uterine endometrial tissue sample brush |
US527,838 | 1995-09-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2185266A1 true CA2185266A1 (en) | 1997-03-14 |
CA2185266C CA2185266C (en) | 2007-10-23 |
Family
ID=24103143
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002185266A Expired - Lifetime CA2185266C (en) | 1995-09-13 | 1996-09-11 | Uterine endometrial tissue sample brush |
Country Status (8)
Country | Link |
---|---|
US (1) | US5713369A (en) |
EP (1) | EP0763345B1 (en) |
JP (1) | JP3851387B2 (en) |
AU (1) | AU696674B2 (en) |
CA (1) | CA2185266C (en) |
DE (1) | DE69633966T2 (en) |
ES (1) | ES2229256T3 (en) |
HK (1) | HK1013945A1 (en) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999053841A1 (en) | 1998-04-23 | 1999-10-28 | Cook Urological, Inc. | Endocervical and exocervical cell collection device |
CA2355661C (en) * | 1998-07-23 | 2006-04-11 | The Oralscan/Trylon Joint Venture | Apparatus and method for obtaining transepithelial specimen of a body surface using a non-lacerating technique |
JP2003524443A (en) * | 1998-08-02 | 2003-08-19 | スーパー ディメンション リミテッド | Medical guidance device |
KR19980082053A (en) * | 1998-08-17 | 1998-11-25 | 정혁 | Structure of cervical cancer screening brush |
US6143512A (en) * | 1998-08-17 | 2000-11-07 | Markovic; Nenad | Cap-pap test |
NL1010709C2 (en) * | 1998-12-02 | 2000-06-19 | Mdz Beheer B V | Brush suitable for taking a smear. |
AU769471B2 (en) * | 1999-02-23 | 2004-01-29 | Cdx Laboratories, Inc. | Minimally invasive apparatus and method for testing lesions of the oral cavity and similar epithelium |
US6387058B1 (en) * | 2000-10-13 | 2002-05-14 | Wallach Surgical Devices, Inc. | Self-sampling brush and method for use |
JP4589572B2 (en) * | 2001-06-27 | 2010-12-01 | Hoya株式会社 | Endoscopic cytology brush |
US7722613B2 (en) * | 2002-09-11 | 2010-05-25 | Nuvasive, Inc. | Systems and methods for removing body tissue |
US20040260199A1 (en) * | 2003-06-19 | 2004-12-23 | Wilson-Cook Medical, Inc. | Cytology collection device |
US20050256426A1 (en) * | 2004-05-12 | 2005-11-17 | William Brugge | Apparatus and method for collecting tissue samples |
US20050277846A1 (en) * | 2004-06-09 | 2005-12-15 | Chun-Shan Chou | Cervical tissue sampling device |
DE102004040868A1 (en) | 2004-08-23 | 2006-03-09 | Miloslavski, Elina | Device for removing thrombi |
US20070106174A1 (en) * | 2005-10-07 | 2007-05-10 | Femspec Llc | Intrauterine anesthetic applicator and cell collection device and method of use |
US20070173736A1 (en) * | 2005-10-07 | 2007-07-26 | Femspec Llc | Apparatus and methods for endometrial biopsies |
US7517323B2 (en) * | 2006-05-19 | 2009-04-14 | Ng Raymond C | Rotary device to gather mucous for testing |
US8439847B2 (en) * | 2006-06-01 | 2013-05-14 | Daniel Larkin | Method and apparatus for simultaneously collecting exocervical and endocervical samples |
US8323211B2 (en) * | 2006-06-01 | 2012-12-04 | Daniel Larkin | Sexually transmitted infection sampling device |
US7749173B2 (en) | 2006-06-01 | 2010-07-06 | Daniel Larkin | Apparatus for simultaneously collecting exocervical and endocervical samples |
EE05470B1 (en) * | 2006-06-09 | 2011-10-17 | Eesti Maa�likool | Apparatus for collecting toxicological, bacteriological and cervical samples |
US8795197B2 (en) * | 2007-07-17 | 2014-08-05 | Histologics, LLC | Frictional trans-epithelial tissue disruption collection apparatus and method of inducing an immune response |
KR20100105829A (en) | 2007-07-17 | 2010-09-30 | 히스톨로직스 엘엘씨 | Frictional trans-epithelial tissue disruption and collection apparatus and method of inducing and/or augmenting an immune response |
US20090076411A1 (en) * | 2007-09-17 | 2009-03-19 | Syed Rizvi | Endometrial anesthesia delivery device and methods of use thereof |
US8282612B1 (en) * | 2008-03-07 | 2012-10-09 | Denise H. Miller | Methods and devices for intrauterine absorption |
US9575140B2 (en) | 2008-04-03 | 2017-02-21 | Covidien Lp | Magnetic interference detection system and method |
EP2297673B1 (en) | 2008-06-03 | 2020-04-22 | Covidien LP | Feature-based registration method |
US8218847B2 (en) | 2008-06-06 | 2012-07-10 | Superdimension, Ltd. | Hybrid registration method |
US8348856B1 (en) | 2008-12-16 | 2013-01-08 | Zanetta Malanowska-Stega | Simultaneous multiple method out-patient uterus biopsy device and method |
NL2003379C2 (en) * | 2009-08-21 | 2011-02-23 | Rovers Holding B V | SAMPLING DEVICE AND METHOD FOR PREPARING THEM. |
US9044213B1 (en) | 2010-03-26 | 2015-06-02 | Histologics, LLC | Frictional tissue sampling and collection method and device |
ES2621812T3 (en) | 2010-05-10 | 2017-07-05 | Mayo Foundation For Medical Education And Research | Detection of chromosomal abnormalities associated with endometrial cancer |
EP2629676B1 (en) * | 2010-10-19 | 2016-07-13 | United States Endoscopy Group, Inc. | Cytology brush apparatus with improvements |
WO2012170380A2 (en) * | 2011-06-07 | 2012-12-13 | Linnemeier Georgiann C | Method for the early detection of high-grade pelvic serous cancer |
US9078786B1 (en) | 2012-10-19 | 2015-07-14 | Denise H. Miller | Methods and devices for collecting body fluids |
US10201332B1 (en) | 2012-12-03 | 2019-02-12 | Healoe Llc | Device and method of orienting a biopsy device on epithelial tissue |
BR112015018524A2 (en) | 2013-02-01 | 2017-07-18 | Nvision Medical Corp | process to collect cells from an individual's lumen and catheter |
US10639016B2 (en) | 2013-02-01 | 2020-05-05 | Boston Scientific Scimed, Inc. | Methods and devices for Fallopian tube diagnostics |
US9320502B2 (en) | 2013-03-12 | 2016-04-26 | Cook Medical Technologies Llc | Cytology balloon |
US9095330B2 (en) | 2013-03-13 | 2015-08-04 | Cook Medical Technologies Llc | Perforated tube for cell collection |
US9039637B2 (en) | 2013-03-13 | 2015-05-26 | Cook Medical Technologies Llc | Flexible cytology coil |
US9119609B2 (en) | 2013-03-13 | 2015-09-01 | Cook Medical Technologies Llc | Rotating cell collection device |
US9655600B2 (en) * | 2013-05-03 | 2017-05-23 | Femasys Inc. | Methods and devices for endometrial cell and tissue sampling |
JP5686853B2 (en) * | 2013-06-13 | 2015-03-18 | デンカ生研株式会社 | Swab for collecting biological specimen, method for producing the swab, and kit using the swab |
US9750483B2 (en) * | 2013-06-26 | 2017-09-05 | Boston Scientific Scimed, Inc. | Cytology brush devices and methods of use |
JP6689206B2 (en) | 2014-05-02 | 2020-04-28 | ユナイテッド ステイツ エンドスコピー グループ,インコーポレイテッド | Endoscope cleaning device |
US11096677B2 (en) * | 2014-09-18 | 2021-08-24 | Covidien Lp | Regions of varying physical properties in a compressible cell collection device |
USD790863S1 (en) * | 2015-04-15 | 2017-07-04 | Brivaplast S.R.L. | Mascara brush |
US11013466B2 (en) | 2016-01-28 | 2021-05-25 | Healoe, Llc | Device and method to control and manipulate a catheter |
CN105997191B (en) * | 2016-06-23 | 2021-03-23 | 高明东 | Phlegm bolt cleaning device |
US10722311B2 (en) | 2016-10-28 | 2020-07-28 | Covidien Lp | System and method for identifying a location and/or an orientation of an electromagnetic sensor based on a map |
US10517505B2 (en) | 2016-10-28 | 2019-12-31 | Covidien Lp | Systems, methods, and computer-readable media for optimizing an electromagnetic navigation system |
US10418705B2 (en) | 2016-10-28 | 2019-09-17 | Covidien Lp | Electromagnetic navigation antenna assembly and electromagnetic navigation system including the same |
US10615500B2 (en) | 2016-10-28 | 2020-04-07 | Covidien Lp | System and method for designing electromagnetic navigation antenna assemblies |
US10751126B2 (en) | 2016-10-28 | 2020-08-25 | Covidien Lp | System and method for generating a map for electromagnetic navigation |
US10792106B2 (en) | 2016-10-28 | 2020-10-06 | Covidien Lp | System for calibrating an electromagnetic navigation system |
US10446931B2 (en) | 2016-10-28 | 2019-10-15 | Covidien Lp | Electromagnetic navigation antenna assembly and electromagnetic navigation system including the same |
US10638952B2 (en) | 2016-10-28 | 2020-05-05 | Covidien Lp | Methods, systems, and computer-readable media for calibrating an electromagnetic navigation system |
CN106344130A (en) * | 2016-11-15 | 2017-01-25 | 深圳市盐田区人民医院 | Automatic induced abortion device without uterus dilatation |
KR20190104148A (en) | 2016-12-09 | 2019-09-06 | 자네타 말라노브스카-스테가 | Brush Biopsy Devices, Kits, and Methods |
WO2019064124A1 (en) * | 2017-09-29 | 2019-04-04 | Gilbert Lucy | Intrauterine sample collection device and method of using same |
CN108903979B (en) * | 2018-07-20 | 2021-01-29 | 泰山医学院 | Cervical pathology sampling device |
US20210239579A1 (en) * | 2018-08-13 | 2021-08-05 | Accroma Labtec Ag | Automated preparation of sample materials for chemical analysis |
DE102021115486A1 (en) | 2021-06-15 | 2022-12-15 | Joimax Gmbh | Medical instrument, medical instrument set, medical device and medical procedure |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2701559A (en) * | 1951-08-02 | 1955-02-08 | William A Cooper | Apparatus for exfoliating and collecting diagnostic material from inner walls of hollow viscera |
GB1408140A (en) * | 1971-12-09 | 1975-10-01 | Levene M M | Sampling device |
US4227537A (en) * | 1978-03-08 | 1980-10-14 | Tucson Medical Instruments, Inc. | Endometrial brush with slidable protective sleeve |
US4235244A (en) * | 1978-07-27 | 1980-11-25 | Medi-Tech, Incorporated | Microbiological specimen sampling device |
US4759376A (en) * | 1984-05-29 | 1988-07-26 | Nils Stormby | Endocervical sampling brush and smear method |
GB2159420B (en) * | 1984-05-29 | 1988-05-11 | Medscand Ab | Endocervical sampling brush and smear method |
US4763670A (en) * | 1986-09-19 | 1988-08-16 | Microvasive, Inc. | Microbiological specimen sampling device |
US4754764A (en) * | 1987-03-20 | 1988-07-05 | Medical Dynamics, Inc. | Cervical cytology device |
US4966162A (en) * | 1989-01-25 | 1990-10-30 | Wang Ko P | Flexible encoscope assembly |
SE465451B (en) * | 1990-05-10 | 1991-09-16 | Medscand Ab | INSTRUMENTS FOR ENDO- AND ECTOCERVIC SAMPLING |
US5133361A (en) * | 1990-09-21 | 1992-07-28 | Lanita Cox | Biopsy brush |
US5201323A (en) * | 1991-02-20 | 1993-04-13 | Brigham & Women's Hospital | Wire-guided cytology brush |
US5217023A (en) * | 1991-04-03 | 1993-06-08 | Langdon Medical, Inc. | Cytology collection device and method |
US5184626A (en) * | 1991-05-21 | 1993-02-09 | Hicken William J | Brush overlay Pap smear |
US5146928A (en) * | 1992-01-30 | 1992-09-15 | Theodor Esser | Sampling device for collecting microbiological biopsy specimen |
US5253652A (en) * | 1993-01-25 | 1993-10-19 | Fast James I | Cytologic sampling device for collecting cervical and vaginal cell specimens |
US5456265A (en) * | 1993-09-28 | 1995-10-10 | Yim; Duck S. | Endocervical brush assembly and method for obtaining tissue samples |
US5370128A (en) * | 1993-12-02 | 1994-12-06 | Wainwright; Sharon R. | Pap brush and pap unit container systems |
-
1995
- 1995-09-13 US US08/527,838 patent/US5713369A/en not_active Expired - Lifetime
-
1996
- 1996-09-10 EP EP96306567A patent/EP0763345B1/en not_active Expired - Lifetime
- 1996-09-10 ES ES96306567T patent/ES2229256T3/en not_active Expired - Lifetime
- 1996-09-10 DE DE69633966T patent/DE69633966T2/en not_active Expired - Lifetime
- 1996-09-11 CA CA002185266A patent/CA2185266C/en not_active Expired - Lifetime
- 1996-09-12 AU AU65604/96A patent/AU696674B2/en not_active Expired
- 1996-09-12 JP JP26227696A patent/JP3851387B2/en not_active Expired - Fee Related
-
1998
- 1998-12-24 HK HK98115428A patent/HK1013945A1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2185266C (en) | 2007-10-23 |
DE69633966D1 (en) | 2005-01-05 |
EP0763345A1 (en) | 1997-03-19 |
JPH09108227A (en) | 1997-04-28 |
AU696674B2 (en) | 1998-09-17 |
HK1013945A1 (en) | 1999-09-17 |
AU6560496A (en) | 1997-03-20 |
EP0763345B1 (en) | 2004-12-01 |
JP3851387B2 (en) | 2006-11-29 |
US5713369A (en) | 1998-02-03 |
ES2229256T3 (en) | 2005-04-16 |
DE69633966T2 (en) | 2005-10-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20160912 |