CA2189039C - Medical linear actuator for surgical delivery, manipulation, and extraction - Google Patents

Medical linear actuator for surgical delivery, manipulation, and extraction Download PDF

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Publication number
CA2189039C
CA2189039C CA002189039A CA2189039A CA2189039C CA 2189039 C CA2189039 C CA 2189039C CA 002189039 A CA002189039 A CA 002189039A CA 2189039 A CA2189039 A CA 2189039A CA 2189039 C CA2189039 C CA 2189039C
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Canada
Prior art keywords
cannula
plunger
source
motive power
members
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Expired - Fee Related
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CA002189039A
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French (fr)
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CA2189039A1 (en
Inventor
John Giungo
Daniel B. Schein
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Photogenesis Inc
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Photogenesis Inc
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F11/00Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/320016Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes
    • A61B17/32002Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes with continuously rotating, oscillating or reciprocating cutting instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3468Trocars; Puncturing needles for implanting or removing devices, e.g. prostheses, implants, seeds, wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/30Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/30Surgical pincettes without pivotal connections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017Electrical control of surgical instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00367Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
    • A61B2017/00398Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like using powered actuators, e.g. stepper motors, solenoids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/0046Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable
    • A61B2017/00464Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable for use with different instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00973Surgical instruments, devices or methods, e.g. tourniquets pedal-operated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/28Surgical forceps
    • A61B17/29Forceps for use in minimally invasive surgery
    • A61B2017/2926Details of heads or jaws
    • A61B2017/2932Transmission of forces to jaw members
    • A61B2017/2933Transmission of forces to jaw members camming or guiding means
    • A61B2017/2937Transmission of forces to jaw members camming or guiding means with flexible part
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2217/00General characteristics of surgical instruments
    • A61B2217/002Auxiliary appliance
    • A61B2217/005Auxiliary appliance with suction drainage system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/9517Instruments specially adapted for placement or removal of stents or stent-grafts handle assemblies therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/00736Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • A61F9/00763Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments with rotating or reciprocating cutting elements, e.g. concentric cutting needles

Abstract

This invention is a linear actuator assembly (10) for oper-ating a plurality of surgical tools. The actuator (40) can provide motive power to the surgical tools which are attachable to a hand-piece (100) associated with the actuator assembly and may be foot pedal (38) operated. In a preferred embodiment, the actuator is electromechanically driven (10) and microprocessor-controlled (22). Embodiments of the device may be used for surgeries, such as but not limited to, retinal surgery, biopsies, and stent removal.

Description

MEDICAL LINEAR ACTUATOR FOR SURGICAL DELIVERY, MANIPULATION, AND EXTRACTION
BACKGROUND OF THE INVENTION
The present invention relates in general to surgical instruments and surgical techniques. More particularly, the present invention is directed to a linear actuator for a multifunctional surgical tool for delivery of grafts, drugs, devices, and for irrigation/aspiration of various parts of the body; as well as surgical manipulation and extraction.
There is a need for a device to deliver, extract, and implant medical devices, drugs, tissue, etc. to various parts of the body. Such a device must be capable of delivering an implant in a target site in the body in a controlled, calibrated fashion where necessary. There is a need for implantation of neural and other living tissue, an increasing number of surgical devices, and drugs. In addition, existing implants frequently require treatment involving manipulation and extraction procedures. By way of non-limiting example, a significant number of patients receive vascular prosthetics, e.g. stems, which are provided by way of a catheter. It is desirable that vascular prosthetics and grafts be expressed from the catheter in a controlled and calibrated fashion.
Further, there is a need to alter the position of such prosthetic devices in the body or to extract these devices.
Likewise, there is a need to deliver, manipulate, and extract other medical and therapeutic devices.
Many self powered surgical tools have been developed which are capable of performing the previously mentioned tasks. Most of these tools have pneumatic drive means. U.S.
Patent No. 5,019,035 issued to Missirlian et al. discloses one such device. Missirlian describes a pneumatically operated 2 1 0 90 ~9 microsurgical cutting instrument. A spring biased inner cutting member moves in a first direction relative to a stationary cutting member in response to the applied air pressure. A spring returns the inner cutting member to its original position. This system, like all pneumatic systems suffers from an inherent hysteresis in the system. This hysteresis limits the control that the operator has over the implement thereby complicating delicate procedures. Also, pneumatic systems tend to impart a "jerky" movement to the implement further affecting the precision and accuracy with which the tool can be effectively used. Finally, the pneumatic systems can be subject to leaky and clogged supply/vacuum lines which can affect performance.
U.S. Pat. No. 4,837,857 issued to Scheller et al.
discloses a foot pedal assembly which can be used for remotely controlling a variety of microsurgical instruments. The system employs pneumatic drive means and is thereby subject to the aforementioned drawbacks.
SUMMARY OF THE INVENTION
The invention provides a device for surgical delivery, manipulation, and extraction of surgical material and devices, comprising: a source of motive power; a cannula having a tip with an opening therein, said tip being insertable into a patient to permit surgical delivery, manipulation, and extraction of material and devices; a plunger having first and second end portions, said first end portion connected to said source of motive power, said source of motive power capable of selectively imparting linear motion to said plunger, said device also having means for adjustment of the speed of said plunger, and means for adjustment of the direction of travel of said plunger, said plunger capable of being partially disposed within said cannula so that said second end may linearly move within said cannula; means to limit said linear motion of said plunger with respect to said cannula, said limit means being adjustable; wherein a plurality of functional attachments can be operably connected to or engaged by said second end portion one at a time to deliver, manipulate, cut, or extract via said opening of said cannula in operable relation with the motion of said plunger, wherein, when said functional attachment is an implant contained within said cannula and said cannula is to be used to deliver an implant into a patient, said tip is insertable into the patient, and said second end of said plunger can be extended into said cannula to cause the expression of said implant into the patient.
A microprocessor controlled drive means is adaptable for use with a plurality of functional attachments including, but not limited to, cutting tools, grasping tools, and tools useful for implantation of various devices, tissues, grafts, and drugs into the body.
Generally, the microprocessor controlled drive means comprises a source of motive power, a linear actuator, and a microprocessor to selectively apply power to the linear actuator. The microprocessor can control the direction, speed, length of travel, and duration that power is applied to the linear actuator.
- 2a -The linear actuator of the present invention provides previously unobtainable levels of accuracy and precision in the controlled surgical delivery and manipulation of materials and devices, particularly in surgery beneath and around the retina, other parts of the eye, and in remote portions of blood vessels from the surgical delivery incision.
The linear actuator may be a cable or thin tubular plunger disposed within a second tubular body and capable of relative axial movement therein. In alternative embodiments, the plunger may be actuated manually, by a spring loaded foot pedal assembly, or by a foot pedal operated ratchet wheel assembly.
Other objects and features of the invention will be in part apparent and in part pointed out hereinafter with reference to the following description of non-limiting embodiments.
BRIEF DESCRIPTT_ON OF THE DR_AWTNr~
Fig. 1 is a top elevation view of a housing for a source of motive power for the surgical instrument.
Fig. 2 is a top plan view of the interior components of Fig. 1.
Figs. 3(a)-(e) are schematics of the control circuitry used to selectively supply power to the surgical instrument.
Fig. 4 is a partial sectional view of a handpiece cable assembly including fittings for the linear actuator, infusion line, and the fiber optic cable.
Fig. 5 is a perspective view of a functional attachment to the linear actuator of the present invention for containing an implant for implantation or for extraction of a material.
Fig. 6(a) is a sectional view of a functional attachment to the linear actuator of the present invention including grasping members which are outwardly biased.
Fig. 6(b) is a sectional view of a functional attachment to the linear actuato~..of the present invention including grasping forceps which can be inwardly biased.
Figs. 6(c) and 6(d) are views of a stmt having an inner lip capable of engagement with the grasping members illustrated in Fig. 6(a).
Fig. 7 is a sectional view of a handpiece cable assembly which can be operably connected to a source of motive power.
Fig. 8 is a perspective view of an alternative hand actuated embodiment of the surgical instrument.
Fig. 9 is a partially exploded perspective view of Fig.
8.
DETAILED DESCRIPTION
Referring now to Figures 1 and 2, a top view of a preferred embodiment of a microprocessor controlled electromechanical drive assembly 10 is shown. The assembly 10 includes stepper motors 12 and 14 (Figure 2) which are contained within a housing 16. It should be noted that while an electromechanical drive is a preferred means for providing motive power, a mechanical drive mechanism obtains power from the energy stored in a spring or like mechanism may also be used. Attached to the housing 16 is a front panel 18 and a source of fluid pressure or suction in the form of a syringe 20, the fluid pressure or suction being controlled by stepper motor 14. The housing 16 can also contain a light source for illuminating a fiber optic filament as will be discussed later. A laser source could also be provided.
Both of the stepper motors 12 and 14 are controlled by a microprocessor 22. A plurality of switches and terminals are disposed on the front panel 18 to allow the operator to select the various functions and modes of operation used with the __ T __..

various functional attachments.
Power is selectively applied to the assembly 10 by power switch 24. DC power is supplied to the microprocessor by the transfortner/rectifier assembly 26. The mode switch 28 allows the operator to alternate between actuation of the plunger 29 and the syringe 20. The plunger 29 is alternated between delivery and retraction by switch 30 which, depending on the position of the mode switch 28, also alternates the fluid pressure source, syringe 20, between infusion and aspiration.
Thus in the embodiment of Figs. 1 and 2, delivery or retraction of the plunger 29 is mutually exclusive of infusion or aspiration. In an alternative embodiment, infusion/aspiration can be performed simultaneously with delivery/retraction of the plunger 29. In either embodiment, separate conduits and associated drive means can be used to apply infusion and aspiration simultaneously to a functional attachment.
Pushbutton switch 32 controls the connecting and disconnecting of a functional attachment to device 10, with the connect status being indicated by LEDs 34. The delivery speed of the plunger 29 is infinitely variable over a range of speeds by speed control 36. The range of speeds is variable depending upon the exact procedure being performed and the associated functional attachment. The speed range can be altered if necessary to operate certain functional attachments. Actuation of the plunger 29 is controlled by footswitch 38 which may be a commercially available footswitch such as a model produced under the trademark Linemaster°. The footswitch 38 will operate the plunger 29 or the syringe 20 in the selected direction and speed as long as it is depressed.
The assembly 10 includes an actuator 40 for advancing and WO X6/26696 ~ ~ $ g p ~ ~ PCT/US96/02270 retracting the plunger 29 which is connected to motor 12 via screw drive 42 and has solenoid controlled locking mechanisms 44 and 46. Locking mechanism~44 locks onto the connector 48 of sheath 50 and locking mechanism 46 locks onto the plunger 29. The connector 48 is adapted to be secured within terminal 52 when mechanism 44 locks onto annular recess 54 of the connector 48 (Fig. 4). The connector 48 has an axial bore 56 for slidably receiving the plunger 29. The sheath 50 is secured within the connector bore 56 by an adhesive, by frictional engagement, or is integrally attached. The opposite end of the sheath 50 is secured to a functional attachment.
Thus, when locking mechanisms 44 and 46 are locked onto the connector 48 and plunger 29 respectively, movement of the actuator 40 causes movement of the plunger 29 within axial bore 56 and sheath 50 as the connector and sheath are held stationary relative to the actuator. Locking mechanism 46 moves with the actuator 40 along slide member 58.
Referring again to Fig. 2, the actuator travel 40 is limited by limit switches 60 and 62. The limit switches are actuated by transversely extending arm 64 and serve tc physically limit the travel of the actuator 40 as well as interrupt the supply of power to stepper motor 12.
In a preferred embodiment, the syringe 20 is releasably mounted in syringe support 66. The support 66 includes a rectangular clamp 68 having a groove therein which is sized for holding the syringe 20. The clamp 68 has a threaded aperture extending therethrough, the aperture corresponding to an aperture in the support 66, both apertures aligned for receiving a screw 70 for tightening the clamp 68 onto the syringe 20. A recess 72 formed in the support is adapted to hold the annular flange 74 of the syringe 20 thereby preventing axial movement of the syringe. The syringe actuator _. _ .._ . T

76 has a similar recess 78 for retaining the annular lip 80 at the tip of the syringe piston rod enabling the actuator to move the piston 82 to effect infusion or aspiration.
The syringe 20 is filled with infusion fluid from a second syringe 84 via 3-way stopcock 86. The stopcock 86 is positioned to allow fluid flow from second syringe 84 to syringe 20 at startup. The stopcock 86 is then repositioned to allow fluid flow or suction through infusion/aspiration terminal 87 to the infusion line 88.
The travel of actuator 76 is limited by actuator arm 77 and limit switches 90 and 92 in the same manner as actuator 40. It should be noted that the limit switches can be repositioned to adjust the travel of the actuators 40 and 76.
It should be noted that a pump, fluid reservoir, and a fluid collection container (not shown) may be used to apply fluid flow or aspiration to infusion line 88. A pump such as a peristaltic pump would provide suitable control of flow, and the infusion line 88 or other suitable conduit could be inserted into the pump drive mechanism. Such a pump could have the motor inside the housing of device 10, and have the pump and tubing connection external to the housing.
Referring now to Fig. 3, the microprocessor 22 circuitry is shown. Microcontroller U3 is the main control unit for the microprocessor 22. An Intel(R) 8031 may be used for U3.
Microcontroller U3 is controlled in accordance with the following program.
U1 is a data latch which is used to latch data coming from U3 and may be a 74HC245 integrated circuit. U2 is also a data latch and may be a 74HC373 IC. U4 are 74HC08 Quad two input AND gates which are used as temporary data stores. U5 is a 74ALS156 decoder which outputs control signals from the controller U3 for control of the other ICs. U7 is a RAM which WO 96/26696 ~ ~ PCT/US96/02270 stores data such as speed control for access as needed by the controller U3. An MCM6v~4-55C 64K RAM may be used for U7. U13 are 74HC32 Quad two input OR gates. U8 is programmed to perform as 3 eight bit ports. Port A and Port B are used as inputs. Port C is used as an output. The inputs are from the panel switches or the limit switches in the control box. The outputs are indicators such as LEDs 311. U8 may be a 8255 IC
and is controlled by U3.
U9 and U11 are UCN5804B microcontrollers and are used to drive the stepper motors 12 and 14. U9 and U11 respond to control signals from U3.
U12 is a ADC0808CCJA 8 bit A/D converter used to convert the input voltage from the footswitch to a digital format that the controller recognizes. U10 is a 74HC74 flip-flop which divides the clock pulse by 2 since U12 cannot convert data as fast as U3.
U14 is a 7407 hex buffer that responds to control signals from U3 to turn on the relays which activate the solenoids which operate locking mechanisms 44 and 46.
Thus, a drive means for a linear actuator which is capable of being operably connected to a functional attachment has been described.
A functional attachment capable of implantation of grafts, tissues, or drugs; as well as irrigation, aspiration or removal of tissue includes a handpiece cable assembly as is shown in Fig. 4. The handpiece cable assembly can be operatively connected to the microprocessor controlled drive assembly 10 and can be used for a retinal transplant procedure as described in copending U.S. patent application entitled "METHOD FOR TRANSPLANTATION OF PLANAR IMPLANTS AND SURGICAL
INSTRUMENT THEREFOR" filed on even date herewith which is herein incorporated by reference.
WO 96/26696 S, PCT/US96/02270 Referring now to Fig. 5, the hamdpiece cable assembly includes a handpiece 100 which is sectional and which has a delivery cannula 102 within which plunger 29 is axially movable to express the graft, drug, material, or device to be implanted. The handpiece 100 also includes an infusion lumen 104 which can be connected to infusion tube 88 for providing a source of infusion fluid or aspiration, as well as a fiber optic cable 106 which can be connected to a source of illumination for providing illumination at the site of implantation. Alternatively, a laser source can be connected to fiber optic cable 106 for, e.g., cauterizing blood vessels.
The sheath 50 is connected to the delivery cannula 102 to allow for passage of the plunger 29 into the delivery cannula for expressing the desired implant from the tubular tip 114 of the cannula.
In operation, the handpiece cable assembly is set up for the implantation of the graft by manually inserting the plunger 29 into and through the connector 48 and sheath 50 until the plunger enters a first section of the handpiece 100 and abuts the inner end wall 112 of the calibration cap 112 as shown in Fig. 4. The calibration cap 110 is adapted for detachable locking engagement with the first section of the handpiece 100 and is used to preset the initial position of the plunger 29 within the handpiece 100 when the actuator 40 is in the fully retracted position. Thus, the travel of the plunger 29 within the handpiece 100 extends from the preset position to a position of maximum extension within the delivery cannula 102 as determined by the spacing of the limit switches 60 and 62 as has been previously explained. The plunger 29 is made long enough so that an excess length of the plunger 29 protrudes from the connector 48 when the plunger abuts wall 112. The excess length of the plunger 29 is long WO 96126696 ~ ~ PCT/US96/02270 enough to ensure proper engagement with the locking mechanism 46, but not so long as to prevent full insertion of the connector 48 into the terminal 52. To attach the handpiece assembly to the drive the, connect/disconnect switch 32 is depressed thereby deactivating locking mechanisms 44 and 46 and returning the actuator 40 to the fully retracted position as shown in Fig. 2. The plunger 29 and connector 48 can then be inserted into terminal 52. It should be noted that for most procedures the limit switches 60 and 62 do not allow the plunger 29 to travel beyond the opening 114 of the tubular tip of the delivery cannula 102. When connector 48 is fully inserted into terminal 52 a switch (not shown) activates mechanisms 44 and 46 to lock onto annular recess 54 and plunger 29 respectively. Speed control 36 is then set to the desired speed. The foot pedal 38 can then be used to control extension or retraction of the plunger 29 as desired by setting the panel switches to the appropriate positions.
The infusion/aspiration assembly is set up by attaching syringes 20 and 84 to the infusion/aspiration terminal 87 with the syringe clamp 68 being firmly attached to the syringe 20 so as to prevent axial movement of the syringe 20. The syringe 20 is then loaded with infusion fluid from syringe 84 via stopcock 86 by setting the panel switches in the aspiration mode and depressing the foot pedal 38. The stopcock 86 is then repositioned to allow infusion fluid to flow through infusion line 88. Fluid pressure or suction can then be applied to infusion line 88 via microprocessor controlled stepper motor 14 by operating foot pedal 38 with the panel switches in the appropriate positions. It should be noted that a multilumen cannula can be attached to infusion line 88 to aspirate tissue from the subretinal space or other locations, followed by the implant of drugs, grafts, or devices.
_._,..__~..__.~. _...._... T

The assembly can be adapted to provide accurately controlled motive power to a wide variety of functional attachments. Modification of the hardware or software may be required in order to operate certain functional attachments.
Another functional attachment capable of being operably connected to the drive assembly is shown in Fig. 6(a). This attachment requires the connection of a straight cannula 120 to the handpiece 100 which is sufficiently strong that it does not tear under the outward pressure exerted by retraction of outwardly biased members 122 into cannula 120. This may require reinforcement of tip 121, particularly in instances where cannula 120 is made sufficiently flexible to follow the contours of a blood vessel or other lumen into which it has been inserted. This attachment can be used as a stmt retriever and has a pair of outwardly biased grasping members 122 having hook-like ends 124. The opposite ends of the grasping members 122 are attached to the plunger 29 by a connector (not shown) which allows for simultaneous delivery or retraction of the grasping members. When fully retracted, the grasping members 122, and ends 124, do not expand radially beyond the outer dimensions of the cannula 120 allowing for smooth progression of the device through blood vessels or other lumens. When advanced, the grasping members 122 extend outwardly as shown so that the ends 124 can be used to grasp the stmt or other device for removal. (Examples of stems can be seen in U.S. Pat. No. 4,580,568 issued to Gianturco, U.S.
Pat. No. 4,733,665 issued to Palmez, and U.S. 5,135,536, issued to Hillstead.) A stmt 125 is illustrated in Fig. 6(c), and includes inner flexing lip 127 for engagement with ends 124. Inner flexing lip 127 is designed to lie against the inner surface of stmt 125 when inserted so that blood flow biases lip 127 against the inner stmt wall to create a smooth z189~39 surf ace .
Although two members 122 are shown, additional members may be connected to plunger 29 and be biased radially outward to ensure a better grip and manipulation of the stmt . The blood vessel may be dilated in front of stmt 125, for example at position 129 with a balloon dilatation catheter 131 to permit use of the cannula and grasping elements of the device shown in 6(a) to be inserted through a lumen passing through the balloon dilatation catheter into the st mt 125, and permitting retraction of the stmt 125 into the lumen of the balloon dilatation catheter.
A forceps-like grasping attachment is shown in Fig. 6(b).
This attachment may be used for removal of tissues or devices, or for the manipulation of various devices within the body, and is attached to the drive assembly 10 in the same manner as the attachment of Fig.6(a). The attachment has grasping members 126 which are biased outwardly to open upon advancement of the plunger 29 and to close upon retraction thus allowing the attachment to be used as a miniature forceps.
In one embodiment, the forceps can be inserted through a retinotomy to perform a choroidal biopsy; the members 126 (which can be two or more in number) may also be rotatably connected to plunger 29, and means for rotating members 126 in order to ensure a cleaner incision, or a better cutting and tearing action. A cauterization device (e. g.
electrocauterization probe) can be included to reduce bleeding following the excision of tissue to biopsied and its retraction within cannula 120.
The device can be used for insertion into a lumen of a balloon dilatation catheter for removal of a pre-shrunken (e. g., thermally cooled) stmt, or may be used to both __.~__._..._. ... _ 218~03~
WO 96/26696 PCT/US96/022?0 radially contract and extract a vascular stmt. The cannula 120 in both attachments can be provided with an infusion/aspiration lumen which can be used for irrigation/aspiration at the surgical site.
It should be noted that the devices in Figures 5 and 6 can be effectively employed by making only small surgical incisions.
A handpiece cable assembly 250 having a handpiece 251 which can be functionally attached to a source of motive power is shown in Fig. 7. The handpiece cable assembly 250 includes a delivery cannula 252 which is secured to hollow frusto-conical connector 254 by an adhesive. The main body of the assembly 250 has an inner member 256 and an outer member 258.
The inner member 256 has a frusto-conical portion 260 projecting from one end and a threaded cylindrical post 262 projecting from the opposite end. Connector 254 is adapted for frictional engagement with projecting portion 260 and may be further secured thereto by an adhesive. Outer member 258 has a contoured outer surface 264 to facilitate manipulation of the delivery cannula. A central aperture 266 in the outer member is threaded to enable threaded engagement with post 262 and is inwardly sloped at one end to form a camming surface 268. The post 262 has an aperture 270 adapted to receive a vice member 272 which has an exterior camming surface thereby forming a pin vice assembly comprised of threaded post 262, outer member 258, and vice member 272. Thus, axial movement of the syringe tube 222 within the handpiece 251 is restricted by tightening the pin vice assembly, which causes vice member 272 to compress syringe tube 222 and sheath 224.
If desired infusion/aspiration can be manually effected by securing an infusion/aspiration lumen (not shown) to the exterior of the delivery cannula 252 by using an adhesive, the WO 96/26696 Z ~ PCT/US96/02270 infusion lumen having an opening proximate the opening at the tip 274 of the delivery cannula, the infusion/aspiration lumen being connected to a syringe 276 as shown in Fig. 8.
In another embodiment, plunger 29 may be actuated by a foot pedal operated ratchet assembly (not shown). The ratchet assembly includes two foot pedals, one for delivery, the other for retraction, or a single foot pedal having a directional switch, which reverses the direction of movement of the plunger in response to one up/down cycle of the foot pedal.
The travel per foot pedal cycle can also be adjusted. The plunger 29 will move with each depression of the foot pedal until it reaches its limit of travel, the distance traveled by a single depression being adjustable by the spacings of gear teeth on the ratchet assembly as is well known. Such a ratchet drive assembly may be included with the device 10 as a backup source of motive power.
Manual delivery and retraction of a linear actuator can be accomplished with an alternative embodiment as shown in Figures 11 and 12. In this embodiment the attachment 500 comprises a cylindrical aluminum housing 302 having a delivery cannula 304 attached thereto. A plunger 306 is actuated by thumbswitch 308 which slides in track 310. An actuator 312 is connected to thumbswitch 308 as can be seen in Figure 12.
Actuator 312 is connected to plunger 306 by rod 314 which projects into and through bore 316 in luer connector 317 and is inserted into an aperture 318 at one end of plunger 306 where it is secured therein by an adhesive. Luer connector 317 is connected to the housing 302 and therefore is held stationary relative to rod 314, actuator 312 and plunger 306.
The travel of plunger 306 is limited by set screw 320 which screws into bore 322 and projects into the path of actuator 312. A plurality of bores such as bore 322 can be provided to ~_ _ _. .

WO 96/26696 ~ ~ PCT/U596/02270 adjustably limit the travel of actuator 312 and therefor the plunger 306. Grooves 324 and 326 are provided to hold infusion conduits 328 and 330 in place. Infusion fluid or aspiration can be provided to the infusion conduits 328 and 330 by a syringe.
The delivery cannula 304 is connected to a hollow frusto-conical connector 332 which is secured to housing 302 and has a bore 334 into which the delivery cannula 304 is secured by an adhesive. Conduits 328 and 330 can also be secured to the exterior surfaces of connector 332 and delivery cannula 304 as shown to provide aspiration/infusion at the tip of the delivery cannula. Advancing or retracting the thumbswitch causes advancing or retraction of the plunger 306 within the delivery cannula 304. For further information on the preferred uses and applications of the present invention, reference may be made to copending U.S. patent applications 08/322,735, 08/057,144, 08/033,105, and the application entitiled "METHOD
FOR PREPARATION AND TRANSPLANTATION OF PLANAR IMPLANTS AND
SURGICAL INSTRUMENTS THEREFOR", filed on even date herewith.
Of course, two or more of the features described with respect to the alternate embodiments could be combined, as necessitated by the particular circumstances.
As various changes could be made in the above surgica instruments, compositions of matter and methods withou~
departing from the scope of the invention, it is intended that all matter contained in the above description or shown in the accompanying drawings shall be interpreted as illustrative and not ~n a limiting sense.

Claims (23)

THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A device for surgical delivery, manipulation, and extraction of surgical material and devices, comprising:
a source of motive power;
a cannula having a tip with an opening therein, said tip being insertable into a patient to permit surgical delivery, manipulation, and extraction of material and devices;
a plunger having first and second end portions, said first end portion connected to said source of motive power, said source of motive power capable of selectively imparting linear motion to said plunger, said device also having means for adjustment of the speed of said plunger, and means for adjustment of the direction of travel of said plunger, said plunger capable of being partially disposed within said cannula so that said second end may linearly move within said cannula;

means to limit said linear motion of said plunger with respect to said cannula, said limit means being adjustable;
wherein a plurality of functional attachments can be operably connected to or engaged by said second end portion one at a time to deliver, manipulate, cut, or extract via said opening of said cannula in operable relation with the motion of said plunger, wherein, when said functional attachment is an implant contained within said cannula and said cannula is to be used to deliver an implant into a patient, said tip is insertable into the patient, and said second end of said plunger can be extended into said cannula to cause the expression of said implant into the patient.
2. The device of claim 1 where said source of motive power is microprocessor controlled.
3. The device of claim 1 including means to provide a source of infusion fluid to said functional attachments.
4. The device of claim 1 including means to provide a source of aspiration to said functional attachments.
5. The device of claim 3 where said source of infusion fluid is microprocessor controlled.
6. The device of claim 4 where said source of aspiration is microprocessor controlled.
7. The device of claim 1 including means to provide a source of illumination to said functional attachments.
8. The device of claim 1 where said source of motive power is a manually actuated thumbswitch.
9. The device of claim 1 where said source of motive power is a manually operated ratchet assembly.
10. The device of claim 1 where said source of motive power is an electromechanical drive.
11. The device of claim 1, further comprising a functional attachment comprising at least two members extending from said second end portion of said plunger, each of said members having a proximal end and a distal end, wherein said proximal ends are operably connected to said plunger, and the distal ends of said members are biased radially outward and capable of reciprocating radial movement in response to reciprocating linear movement of said plunger, said cannula having a distal end, said members extending radially outward upon at least partial extension of said members from said distal end of said cannula.
12. The device of claim 11, wherein said members are adapted for cutting tissue upon at least partial linear retraction of said members into the distal end of said cannula from a relatively more extended position.
13. The device of claim 12, wherein said members are adapted for grasping a stent disposed within a blood vessel upon at least partial linear extension of said members from the distal end of said cannula.
14. A device for surgical delivery of material to the eye, comprising:
an electromechanical source of motive power;
a plunger, said plunger having first and second end portions, wherein said first end portion is operably connected to said source of motive power;
a cannula having a plunger end and a tip end, said tip end having an opening therein;
wherein said second end portion of said plunger is capable of insertion into said plunger end of said cannula and movement through said cannula, and said source of motive power is capable of imparting motion to said plunger so that said second end portion of said plunger may move within said cannula;
said cannula having a diameter and a length permitting said cannula to be inserted through incisions in the sclera and retina of an eye so that said opening in said tip end can be located beneath the retina;
wherein motion may be imparted to said plunger by said source of motive power to express an implant contained within said cannula through said opening in said tip end in order to place said implant beneath the retina of an eye into which said cannula is inserted.
15. The device of claim 14, further comprising:
a housing, wherein said source of motive power is contained within said housing, and said cannula is operably connected to said housing via said plunger end, said housing and said source of motive power being of sufficiently small size and weight to permit the device to be held and utilized with one hand.
16. The device of claim 14, further comprising:
an implantable material in said cannula, said implantable material comprising at least one material selected from the group consisting of a photoreceptor cell layer, a retinal pigment epithelial cell layer, and a drug implant.
17. The device of claim 15, further comprising:
an implantable material in said cannula, said implantable material comprising at least one material selected from the group consisting of a photoreceptor cell layer, a retinal pigment epithelial cell layer, and a drug implant.
18. The device of claim 14, including means to adjust the speed, direction, and travel range of said plunger.
19. The device of claim 14, further comprising a manually operated ratchet assembly to provide motive power.
20. A surgical forceps device, comprising:
an electromechanical source of motive power;
a plunger, said plunger having first and second end portions, wherein said first end portion is operably connected to said source of motive power;
a cannula having a plunger end and a tip end, said tip end having an opening therein;
a forceps attachment operably connected to said second end of said plunger;
wherein said second end portion of said plunger is located in said cannula and capable of relative movement with respect to said cannula, and said source of motive power is capable of imparting motion to said plunger so that said second end portion of said plunger may move within said cannula;
said forceps attachment comprises at least two members operably connected to said second end portion of said plunger, the distal ends of said members being directed away from said second end portion of said plunger and being biased radially outward, said distal ends of said members extending radially outward upon at least partial extension of said members from the distal end of said cannula, and wherein, when said distal ends are at least partially extended from said opening in said tip end, said distal ends of said members are capable of reciprocating radial movement in response to reciprocating movement of said plunger within said cannula;
and at least one of said distal ends further comprising a cutting element, wherein said distal ends move away from each other when said members are extended outward and away from said tip end of said cannula, and said distal ends are forced towards each other when said members are retracted into said cannula.
21. The surgical forceps device of claim 20, wherein said cannula has a diameter and a length permitting said cannula to be inserted through incisions in the sclera and retina of an eye so that said opening in said tip end is beneath the retina, wherein motion may be imparted to said plunger by said source of motive power to excise material beneath the retina of an eye into which said cannula is inserted.
22. The surgical forceps device of claim 20, wherein said members are adapted for cutting and extracting tissue upon at least partial linear retraction of said members into the distal end of said cannula from a relatively more extended position.
23. The surgical forceps device of claim 20, wherein said device is capable of excising choroidal tissue in a choroidal biopsy procedure.
CA002189039A 1995-02-28 1996-02-28 Medical linear actuator for surgical delivery, manipulation, and extraction Expired - Fee Related CA2189039C (en)

Applications Claiming Priority (3)

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US08/395,701 US5868728A (en) 1995-02-28 1995-02-28 Medical linear actuator for surgical delivery, manipulation, and extraction
US08/395,701 1995-02-28
PCT/US1996/002270 WO1996026696A1 (en) 1995-02-28 1996-02-28 Medical linear actuator for surgical delivery, manipulation, and extraction

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CA2189039C true CA2189039C (en) 2000-06-27

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JP (1) JPH09509607A (en)
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IL117310A0 (en) 1996-06-18
WO1996026696A1 (en) 1996-09-06
KR970702705A (en) 1997-06-10
AU5415996A (en) 1996-09-18
CA2189039A1 (en) 1996-09-06
IL117310A (en) 2001-11-25
TW304873B (en) 1997-05-11
EP0767641A1 (en) 1997-04-16
EP0767641A4 (en) 2000-03-01
US5868728A (en) 1999-02-09
MX9605181A (en) 1997-12-31
KR100220551B1 (en) 1999-09-15
ZA961598B (en) 1996-09-05
JPH09509607A (en) 1997-09-30

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