CA2194976A1 - Wound healing agent - Google Patents
Wound healing agentInfo
- Publication number
- CA2194976A1 CA2194976A1 CA002194976A CA2194976A CA2194976A1 CA 2194976 A1 CA2194976 A1 CA 2194976A1 CA 002194976 A CA002194976 A CA 002194976A CA 2194976 A CA2194976 A CA 2194976A CA 2194976 A1 CA2194976 A1 CA 2194976A1
- Authority
- CA
- Canada
- Prior art keywords
- wound healing
- healing agent
- chitosan
- polysaccharide
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
The use of chitosan in combination with a first polysaccharide selected from heparin, heparan sulphate and dextran sulphate for the manufacture of an agent that accelerates, stimulates and/or promotes healing of dermal wounds, said polysaccharide, optionally, being immobilized to the chitosan; and a process for the treatment of dermal wounds.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9402531A SE9402531L (en) | 1994-07-19 | 1994-07-19 | wound healing agent |
SE9402531-9 | 1994-07-19 | ||
PCT/SE1995/000875 WO1996002260A1 (en) | 1994-07-19 | 1995-07-18 | Wound healing agent |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2194976A1 true CA2194976A1 (en) | 1996-02-01 |
CA2194976C CA2194976C (en) | 2002-04-30 |
Family
ID=20394771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002194976A Expired - Fee Related CA2194976C (en) | 1994-07-19 | 1995-07-18 | Wound healing agent |
Country Status (11)
Country | Link |
---|---|
US (1) | US5902798A (en) |
EP (1) | EP0759760B1 (en) |
JP (1) | JP3337472B2 (en) |
AT (1) | ATE207753T1 (en) |
AU (1) | AU691322B2 (en) |
CA (1) | CA2194976C (en) |
DE (1) | DE69523585T2 (en) |
DK (1) | DK0759760T3 (en) |
ES (1) | ES2161903T3 (en) |
SE (1) | SE9402531L (en) |
WO (1) | WO1996002260A1 (en) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5576839A (en) * | 1991-09-25 | 1996-11-19 | Minolta Camera Kabushiki Kaisha | Camera system including a separatable recorder |
SE508760C2 (en) | 1997-04-29 | 1998-11-02 | Medicarb Ab | Use of a composition comprising chitosan in combination with a polysaccharide, as an active component in a solvent, for the preparation of a dairy dipping agent for milk producing animals |
NL1011680C2 (en) | 1999-03-26 | 2000-09-27 | Nutricia Nv | Food compositions containing lightly negatively charged, non-digestible polysaccharides and use thereof to reduce transport through tight junctions. |
US6391334B1 (en) | 1999-10-25 | 2002-05-21 | Amway Corporation | Barrier-forming composition |
ES2491866T3 (en) * | 1999-11-15 | 2014-09-08 | Piramal Healthcare (Canada) Limited | Temperature-controlled, pH-dependent, self-gelling aqueous biopolymer solution |
US20030158302A1 (en) * | 1999-12-09 | 2003-08-21 | Cyric Chaput | Mineral-polymer hybrid composition |
AU1979201A (en) * | 1999-12-09 | 2001-06-18 | Bio Syntech Canada Inc | Mineral-polymer hybrid composition |
GB9929472D0 (en) * | 1999-12-13 | 2000-02-09 | Btg Int Ltd | Polymeric film |
JP5089006B2 (en) * | 2000-06-29 | 2012-12-05 | ピラマル ヘルスケア (カナダ) リミテッド | Compositions and methods for repair and regeneration of cartilage and other tissues |
US20040091540A1 (en) * | 2000-11-15 | 2004-05-13 | Desrosiers Eric Andre | Method for restoring a damaged or degenerated intervertebral disc |
US6623761B2 (en) | 2000-12-22 | 2003-09-23 | Hassan Emadeldin M. | Method of making nanoparticles of substantially water insoluble materials |
KR20020066024A (en) * | 2001-02-08 | 2002-08-14 | 굿젠 주식회사 | An ointment composition and film comprising aqueous chitosan and heparin, and wound management products |
JP2004525954A (en) | 2001-04-12 | 2004-08-26 | メディカーブ・アクチエボラーグ | Foamable solid composition |
SE522529C2 (en) | 2001-04-12 | 2004-02-17 | Medicarb Ab | Effervescent solid composition used for treating dermal wounds comprises chitosan or component releasing carbon dioxide in acidic environment |
US7297343B2 (en) * | 2001-07-31 | 2007-11-20 | Biosurface Engineering Technologies, Inc. | Bioactive medical films |
KR20020060627A (en) * | 2002-01-16 | 2002-07-18 | 조석형 | Wound Healing of chitosan/anionic polysaccharides complex |
WO2003070749A2 (en) | 2002-02-15 | 2003-08-28 | Northwestern University | Self-assembly of peptide-amphiphile nanofibers under physiological conditions |
ATE481110T1 (en) * | 2002-07-16 | 2010-10-15 | Biosyntech Canada Inc | COMPOSITION FOR THE PRODUCTION OF CELL-COMPATIBLE, INJECTABLE, SELF-GELELLING CHITOSAN SOLUTIONS FOR ENCAPSULATING AND ADMINISTERING LIVING CELLS OR BIOLOGICALLY ACTIVE FACTORS |
US7554021B2 (en) | 2002-11-12 | 2009-06-30 | Northwestern University | Composition and method for self-assembly and mineralization of peptide amphiphiles |
US20070053848A1 (en) * | 2003-08-26 | 2007-03-08 | Stockel Richard F | Antimicrobial materials for dental care applications |
JP2006347883A (en) * | 2003-09-08 | 2006-12-28 | Neetec:Kk | Composition for medical treatment comprising sugar chain-containing chitosan derivative and glycosaminoglycan |
ES2380340T3 (en) | 2003-12-05 | 2012-05-10 | Northwestern University | Self-assembling peptide amphiphiles and related methods for the administration of growth factors |
US20070086977A1 (en) * | 2003-12-22 | 2007-04-19 | Stockel Richard F | Method of treating dermatological conditions |
US20050136024A1 (en) * | 2003-12-22 | 2005-06-23 | Stockel Richard F. | Dermatological compositions |
US20050283004A1 (en) * | 2004-06-18 | 2005-12-22 | Hopax Chemicals Manufacturing Co., Ltd. | Alkylsulfonated polyaminosaccharides |
CA2598251A1 (en) * | 2005-03-04 | 2006-09-14 | Northwestern University | Angiogenic heparin binding peptide amphiphiles |
US20090149421A1 (en) * | 2005-11-04 | 2009-06-11 | Bio Syntech Canada Inc. | Gel formation of polyelectrolyte aqueous solutions by thermally induced changes in ionization state |
DE102006020035A1 (en) | 2006-04-26 | 2007-10-31 | B. Braun Melsungen Ag | Preparation and use of poly (hydroxyethyl starch) chitin and poly (carboxymethyl starch) chitin compounds |
EP1958613A1 (en) * | 2007-02-15 | 2008-08-20 | Polichem S.A. | Dermal film-forming liquid formulations for drug release to skin |
US8076295B2 (en) | 2007-04-17 | 2011-12-13 | Nanotope, Inc. | Peptide amphiphiles having improved solubility and methods of using same |
CN104874007A (en) | 2007-08-28 | 2015-09-02 | 奥塔哥创新有限公司 | Surgical Hydrogel |
ES2507495T3 (en) * | 2008-11-20 | 2014-10-15 | Laboratori Derivati Organici S.P.A. | Use of heparan sulfate in cosmetological and dermatological preparations |
RU2519225C2 (en) * | 2008-12-06 | 2014-06-10 | Б. Браун Мельзунген Аг | Transport mediating colloidal therapeutic compounds |
BRPI1013656B1 (en) * | 2009-03-31 | 2019-04-30 | B. Braun Melsungen Ag | CONNECTION PRODUCT AND ITS USE, PHARMACEUTICAL FORMULATION AND PROCESS FOR PREPARING A CONNECTION PRODUCT |
EP2419116A1 (en) | 2009-04-13 | 2012-02-22 | North Western University | Novel peptide-based scaffolds for cartilage regeneration and methods for their use |
RU2011152518A (en) * | 2009-06-10 | 2013-07-20 | Экстера Аб | APPLICATION OF THE COMPOSITION FOR TREATMENT OF MUKOZITE |
WO2011026498A1 (en) | 2009-09-01 | 2011-03-10 | Medovent Gmbh | Chitosan tissue dressing |
KR20130018739A (en) | 2010-03-03 | 2013-02-25 | 네오큐티스 에스아 | Compositions and methods for treatment of skin diseases and disorders using antimicrobial peptide sequestering compounds |
US20160193244A1 (en) | 2013-08-13 | 2016-07-07 | Seikagaku Corporation | Drug containing cationized chitosan |
US9192692B2 (en) | 2013-10-24 | 2015-11-24 | Medtronic Xomed, Inc. | Chitosan stenting paste |
US9192574B2 (en) | 2013-10-24 | 2015-11-24 | Medtronic Xomed, Inc. | Chitosan paste wound dressing |
FR3016882A1 (en) | 2014-01-30 | 2015-07-31 | Sofradim Production | PROCESS FOR THE PREPARATION OF HIGH-DEGREE ACETYLATION CHITOSAN |
US10126298B2 (en) | 2015-05-04 | 2018-11-13 | Arman Nabatian | Hydrogels containing embedded substrates for targeted binding of molecules |
US9248160B1 (en) * | 2015-07-28 | 2016-02-02 | Zo Skin Health, Inc. | Post-procedure skin care systems, compositions, and methods of use thereof |
KR20200108020A (en) | 2018-01-12 | 2020-09-16 | 보스톤 싸이엔티픽 싸이메드 인코포레이티드 | Powder to achieve hemostasis |
EP3787593A1 (en) | 2018-05-04 | 2021-03-10 | Bonoss Medical Aktiebolag | A composition for reduction of scar formation |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4378017A (en) * | 1980-03-21 | 1983-03-29 | Kureha Kagaku Kogyo Kabushiki Kaisha | Composite material of de-N-acetylated chitin and fibrous collagen |
US4326532A (en) * | 1980-10-06 | 1982-04-27 | Minnesota Mining And Manufacturing Company | Antithrombogenic articles |
US4532134A (en) * | 1981-04-06 | 1985-07-30 | Malette William Graham | Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound |
US5002582A (en) * | 1982-09-29 | 1991-03-26 | Bio-Metric Systems, Inc. | Preparation of polymeric surfaces via covalently attaching polymers |
CA1202904A (en) * | 1983-11-21 | 1986-04-08 | Brian G. Sparkes | Chitosan based wound dressing materials |
JPS61253065A (en) * | 1985-05-02 | 1986-11-10 | 片倉チツカリン株式会社 | Medical composite material of chitosan derivative and collagen and its production |
US4879282A (en) * | 1987-03-17 | 1989-11-07 | Saliba Jr Michael J | Medical application for heparin and related molecules |
US5037810A (en) * | 1987-03-17 | 1991-08-06 | Saliba Jr Michael J | Medical application for heparin and related molecules |
DE4200080A1 (en) * | 1992-01-03 | 1993-09-30 | Reinmueller Johannes | Pharmaceutical composition for wound, scar and keloid treatment |
JP3205104B2 (en) * | 1992-01-20 | 2001-09-04 | 川研ファインケミカル株式会社 | Cosmetics |
SE9402529D0 (en) * | 1994-07-19 | 1994-07-19 | Astra Ab | Anti-adherents |
-
1994
- 1994-07-19 SE SE9402531A patent/SE9402531L/en not_active Application Discontinuation
-
1995
- 1995-07-18 DE DE69523585T patent/DE69523585T2/en not_active Expired - Lifetime
- 1995-07-18 US US08/765,353 patent/US5902798A/en not_active Expired - Lifetime
- 1995-07-18 ES ES95926574T patent/ES2161903T3/en not_active Expired - Lifetime
- 1995-07-18 DK DK95926574T patent/DK0759760T3/en active
- 1995-07-18 JP JP50496696A patent/JP3337472B2/en not_active Expired - Fee Related
- 1995-07-18 AT AT95926574T patent/ATE207753T1/en not_active IP Right Cessation
- 1995-07-18 WO PCT/SE1995/000875 patent/WO1996002260A1/en active IP Right Grant
- 1995-07-18 EP EP95926574A patent/EP0759760B1/en not_active Expired - Lifetime
- 1995-07-18 AU AU30902/95A patent/AU691322B2/en not_active Ceased
- 1995-07-18 CA CA002194976A patent/CA2194976C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU691322B2 (en) | 1998-05-14 |
SE9402531L (en) | 1996-01-20 |
DE69523585T2 (en) | 2002-04-11 |
CA2194976C (en) | 2002-04-30 |
US5902798A (en) | 1999-05-11 |
EP0759760B1 (en) | 2001-10-31 |
JP3337472B2 (en) | 2002-10-21 |
SE9402531D0 (en) | 1994-07-19 |
JPH10502665A (en) | 1998-03-10 |
ATE207753T1 (en) | 2001-11-15 |
DK0759760T3 (en) | 2001-11-26 |
WO1996002260A1 (en) | 1996-02-01 |
ES2161903T3 (en) | 2001-12-16 |
AU3090295A (en) | 1996-02-16 |
EP0759760A1 (en) | 1997-03-05 |
DE69523585D1 (en) | 2001-12-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20150720 |