CA2199407A1 - Method and apparatus for rapid capture of focused microscopic images - Google Patents
Method and apparatus for rapid capture of focused microscopic imagesInfo
- Publication number
- CA2199407A1 CA2199407A1 CA002199407A CA2199407A CA2199407A1 CA 2199407 A1 CA2199407 A1 CA 2199407A1 CA 002199407 A CA002199407 A CA 002199407A CA 2199407 A CA2199407 A CA 2199407A CA 2199407 A1 CA2199407 A1 CA 2199407A1
- Authority
- CA
- Canada
- Prior art keywords
- image
- output
- capture apparatus
- microscopic images
- camera
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T1/00—General purpose image data processing
- G06T1/60—Memory management
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/26—Stages; Adjusting means therefor
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
- G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/60—Control of cameras or camera modules
- H04N23/67—Focus control based on electronic image sensor signals
- H04N23/673—Focus control based on electronic image sensor signals based on contrast or high frequency components of image signals, e.g. hill climbing method
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/70—Circuitry for compensating brightness variation in the scene
- H04N23/74—Circuitry for compensating brightness variation in the scene by influencing the scene brightness using illuminating means
Abstract
A high speed image capture apparatus (100) includes a camera (102) with an integration period between consecutive flashes of an illuminating light pulse (605), where the camera (102) has an image read out period and an image output. A timer (612) provides a strobe output (608) representative of the start of a flash (605). An image capture apparatus (516) captures a first image during the integration period and a second image within a predetermined time after capturing the first image but before the image read out period (Fig. 7) has elapsed so as to substantially increase a rate of producing usable image outputs. The image capture apparatus (516) is coupled to the strobe output and the image output.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/302,355 | 1994-09-07 | ||
US08/302,355 US5912699A (en) | 1992-02-18 | 1994-09-07 | Method and apparatus for rapid capture of focused microscopic images |
PCT/US1995/010588 WO1996008106A1 (en) | 1994-09-07 | 1995-08-21 | Method and apparatus for rapid capture of focused microscopic images |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2199407A1 true CA2199407A1 (en) | 1996-03-14 |
CA2199407C CA2199407C (en) | 2002-01-01 |
Family
ID=23167407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002199407A Expired - Fee Related CA2199407C (en) | 1994-09-07 | 1995-08-21 | Method and apparatus for rapid capture of focused microscopic images |
Country Status (8)
Country | Link |
---|---|
US (1) | US5912699A (en) |
EP (1) | EP0809911A4 (en) |
JP (1) | JPH10505721A (en) |
AU (1) | AU703583B2 (en) |
CA (1) | CA2199407C (en) |
DE (1) | DE809911T1 (en) |
ES (1) | ES2123471T1 (en) |
WO (1) | WO1996008106A1 (en) |
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US7668362B2 (en) * | 2000-05-03 | 2010-02-23 | Aperio Technologies, Inc. | System and method for assessing virtual slide image quality |
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US7518652B2 (en) * | 2000-05-03 | 2009-04-14 | Aperio Technologies, Inc. | Method and apparatus for pre-focus in a linear array based slide scanner |
US7155049B2 (en) * | 2001-01-11 | 2006-12-26 | Trestle Acquisition Corp. | System for creating microscopic digital montage images |
US6798571B2 (en) | 2001-01-11 | 2004-09-28 | Interscope Technologies, Inc. | System for microscopic digital montage imaging using a pulse light illumination system |
US6993169B2 (en) * | 2001-01-11 | 2006-01-31 | Trestle Corporation | System and method for finding regions of interest for microscopic digital montage imaging |
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DE10156275B4 (en) * | 2001-11-16 | 2006-08-03 | Leo Elektronenmikroskopie Gmbh | Detector arrangement and detection method |
JP4021183B2 (en) * | 2001-11-29 | 2007-12-12 | オリンパス株式会社 | Focus state signal output device |
US7538815B1 (en) * | 2002-01-23 | 2009-05-26 | Marena Systems Corporation | Autofocus system and method using focus measure gradient |
US7257268B2 (en) | 2003-02-28 | 2007-08-14 | Aperio Technologies, Inc. | Systems and methods for image pattern recognition |
US7116440B2 (en) | 2003-02-28 | 2006-10-03 | Aperio Technologies, Inc. | Image processing and analysis framework |
JP2007516009A (en) * | 2003-10-03 | 2007-06-21 | アカデミッシュ メディシュ セントラム | Systems and methods for image processing of substrate reflections. |
JP5134365B2 (en) | 2004-05-27 | 2013-01-30 | アペリオ・テクノロジーズ・インコーポレイテッド | System and method for generating and visualizing a three-dimensional virtual slide |
GB0414201D0 (en) * | 2004-06-24 | 2004-07-28 | Fujifilm Electronic Imaging | Method and apparatus for forming a multiple focus stack image |
DE102004042913A1 (en) * | 2004-09-02 | 2006-03-30 | Westfälische-Wilhelms Universität Münster | Scanner arrangement and method for optically scanning an object |
US9131861B2 (en) * | 2004-11-30 | 2015-09-15 | Academisch Medisch Centrum | Pulsed lighting imaging systems and methods |
WO2006081362A2 (en) | 2005-01-27 | 2006-08-03 | Aperio Technologies, Inc | Systems and methods for viewing three dimensional virtual slides |
GB0503032D0 (en) * | 2005-02-14 | 2005-03-23 | Fujifilm Electronic Imaging | Blip focus |
US7417213B2 (en) * | 2005-06-22 | 2008-08-26 | Tripath Imaging, Inc. | Apparatus and method for rapid microscopic image focusing having a movable objective |
US8164622B2 (en) * | 2005-07-01 | 2012-04-24 | Aperio Technologies, Inc. | System and method for single optical axis multi-detector microscope slide scanner |
EP2036003B1 (en) | 2006-06-30 | 2017-05-03 | Leica Biosystems Imaging, Inc. | Method for storing and retrieving large images via dicom |
US8010555B2 (en) * | 2006-06-30 | 2011-08-30 | Aperio Technologies, Inc. | System and method for managing images over a network |
JP4758331B2 (en) * | 2006-12-08 | 2011-08-24 | オリンパス株式会社 | Microscope imaging apparatus and microscope imaging program |
JP5389016B2 (en) | 2007-05-04 | 2014-01-15 | アペリオ・テクノロジーズ・インコーポレイテッド | System and method for quality assurance in pathology |
US8878923B2 (en) * | 2007-08-23 | 2014-11-04 | General Electric Company | System and method for enhanced predictive autofocusing |
CN101939616B (en) * | 2008-01-09 | 2014-07-09 | 株式会社尼康 | Measuring device, method, and program |
US7706632B2 (en) * | 2008-01-17 | 2010-04-27 | Ffei Limited | Method and apparatus for forming a multiple focus stack image |
US7645971B2 (en) * | 2008-01-18 | 2010-01-12 | Ffei Limited | Image scanning apparatus and method |
US8743195B2 (en) | 2008-10-24 | 2014-06-03 | Leica Biosystems Imaging, Inc. | Whole slide fluorescence scanner |
EP2405647B1 (en) * | 2009-03-03 | 2019-06-12 | Panasonic Corporation | Imaging apparatus which corrects effects of flash |
US20110090327A1 (en) * | 2009-10-15 | 2011-04-21 | General Electric Company | System and method for imaging with enhanced depth of field |
US8314837B2 (en) * | 2009-10-15 | 2012-11-20 | General Electric Company | System and method for imaging with enhanced depth of field |
US20110091125A1 (en) * | 2009-10-15 | 2011-04-21 | General Electric Company | System and method for imaging with enhanced depth of field |
AU2010308550B2 (en) | 2009-10-19 | 2013-05-23 | Ventana Medical Systems, Inc. | Imaging system and techniques |
WO2011072211A2 (en) | 2009-12-11 | 2011-06-16 | Aperio Technologies, Inc. | Improved signal to noise ratio in digital pathology image analysis |
DE102011075369B4 (en) | 2011-05-05 | 2022-02-17 | Carl Zeiss Microscopy Gmbh | Method and device for object imaging |
GB2505691B (en) * | 2012-09-07 | 2018-02-21 | Ffei Ltd | Method and apparatus for image scanning |
GB201409203D0 (en) | 2014-05-23 | 2014-07-09 | Ffei Ltd | Improvements in digitising slides |
GB201409202D0 (en) | 2014-05-23 | 2014-07-09 | Ffei Ltd | Improvements in imaging microscope samples |
JP2017526507A (en) | 2014-08-31 | 2017-09-14 | ベレシュトカ,ジョン | System and method for analyzing eyes |
CN104394323B (en) * | 2014-12-04 | 2018-07-24 | 厦门大学 | A kind of image pickup method of amplification micro-image |
FI20175410A (en) * | 2017-05-08 | 2018-11-09 | Grundium Oy | Apparatus and method for scanning microscope slides |
US10409141B2 (en) * | 2017-09-20 | 2019-09-10 | Qualcomm Incorporated | System and method for improved camera flash |
CN108345101A (en) * | 2018-01-16 | 2018-07-31 | 迪瑞医疗科技股份有限公司 | Lighting system and its method illuminated for motor cell shooting |
EP3611912B1 (en) * | 2018-08-15 | 2022-11-23 | reflecta GmbH | Slide scanner |
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-
1994
- 1994-09-07 US US08/302,355 patent/US5912699A/en not_active Expired - Lifetime
-
1995
- 1995-08-21 JP JP8509517A patent/JPH10505721A/en active Pending
- 1995-08-21 EP EP95930866A patent/EP0809911A4/en not_active Withdrawn
- 1995-08-21 CA CA002199407A patent/CA2199407C/en not_active Expired - Fee Related
- 1995-08-21 ES ES95930866T patent/ES2123471T1/en active Pending
- 1995-08-21 WO PCT/US1995/010588 patent/WO1996008106A1/en not_active Application Discontinuation
- 1995-08-21 AU AU34090/95A patent/AU703583B2/en not_active Ceased
- 1995-08-21 DE DE0809911T patent/DE809911T1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU703583B2 (en) | 1999-03-25 |
WO1996008106A1 (en) | 1996-03-14 |
JPH10505721A (en) | 1998-06-02 |
EP0809911A1 (en) | 1997-12-03 |
AU3409095A (en) | 1996-03-27 |
ES2123471T1 (en) | 1999-01-16 |
CA2199407C (en) | 2002-01-01 |
DE809911T1 (en) | 1998-11-19 |
EP0809911A4 (en) | 1999-10-06 |
US5912699A (en) | 1999-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |