CA2209240A1 - Optical coupler for in vivo examination of biological tissue - Google Patents

Optical coupler for in vivo examination of biological tissue

Info

Publication number
CA2209240A1
CA2209240A1 CA002209240A CA2209240A CA2209240A1 CA 2209240 A1 CA2209240 A1 CA 2209240A1 CA 002209240 A CA002209240 A CA 002209240A CA 2209240 A CA2209240 A CA 2209240A CA 2209240 A1 CA2209240 A1 CA 2209240A1
Authority
CA
Canada
Prior art keywords
optical
tissue
radiation
input port
constructed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002209240A
Other languages
French (fr)
Other versions
CA2209240C (en
Inventor
Britton Chance
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Non Invasive Technology Inc
Original Assignee
Non-Invasive Technology, Inc.
Britton Chance
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/367,939 external-priority patent/US5596987A/en
Priority claimed from PCT/US1995/015694 external-priority patent/WO1996016596A1/en
Priority claimed from PCT/US1995/015666 external-priority patent/WO1996016592A1/en
Application filed by Non-Invasive Technology, Inc., Britton Chance filed Critical Non-Invasive Technology, Inc.
Publication of CA2209240A1 publication Critical patent/CA2209240A1/en
Application granted granted Critical
Publication of CA2209240C publication Critical patent/CA2209240C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077—Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0091—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552—Details of sensors specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14553—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312—Breast evaluation or disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • A61B5/6853—Catheters with a balloon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04—Arrangements of multiple sensors of the same type
    • A61B2562/046—Arrangements of multiple sensors of the same type in a matrix array
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/14—Coupling media or elements to improve sensor contact with skin or tissue
    • A61B2562/146—Coupling media or elements to improve sensor contact with skin or tissue for optical coupling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/0035—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Abstract

An optical coupler for in vivo examination of biological tissue includes an optical input port (19) positionable on or near the examined tissue (40), a first light guide (20) optically coupled to the optical input port and constructed to transmit optical radiation of a visible or infrared wavelength from a source to the optical input port (19). The optical coupler also includes an optical detection port (21), positionable on or near the examined tissue, constructed and arranged to receive radiation that has migrated in the examinated tissue from the input port (19).
Connected to the detection port (21) is a detector light guide (22), constructed to transmit radiation from the detection port to an optical detector. Disposed at least partially around the examined tissue and the input and detection ports is optical medium (12) arranged to couple the radiation to the tissue, limit escape of photons, or account for photons that escaped from the tissue.
CA002209240A 1995-01-03 1996-01-02 Optical coupler for in vivo examination of biological tissue Expired - Lifetime CA2209240C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US08/367,939 1995-01-03
US08/367,939 US5596987A (en) 1988-11-02 1995-01-03 Optical coupler for in vivo examination of biological tissue
WOPCT/US95/15694 1995-12-04
PCT/US1995/015694 WO1996016596A1 (en) 1994-12-02 1995-12-04 Optical techniques for examination of biological tissue
PCT/US1995/015666 WO1996016592A1 (en) 1994-12-02 1995-12-04 Monitoring one or more solutes in a biological system using optical techniques
WOPCT/US95/15666 1995-12-04
PCT/US1996/000235 WO1996020638A1 (en) 1995-01-03 1996-01-02 Optical coupler for in vivo examination of biological tissue

Publications (2)

Publication Number Publication Date
CA2209240A1 true CA2209240A1 (en) 1996-07-11
CA2209240C CA2209240C (en) 2009-07-21

Family

ID=23449241

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002209240A Expired - Lifetime CA2209240C (en) 1995-01-03 1996-01-02 Optical coupler for in vivo examination of biological tissue

Country Status (7)

Country Link
US (5) US5987351A (en)
EP (2) EP0808124B1 (en)
JP (1) JP3725156B2 (en)
CN (1) CN1230118C (en)
CA (1) CA2209240C (en)
DE (1) DE69627477T2 (en)
WO (2) WO1996020638A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8060189B2 (en) 2005-05-06 2011-11-15 Infrascan, Inc. System and method for detection of hematoma

Families Citing this family (175)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5353799A (en) 1991-01-22 1994-10-11 Non Invasive Technology, Inc. Examination of subjects using photon migration with high directionality techniques
US5853370A (en) 1996-09-13 1998-12-29 Non-Invasive Technology, Inc. Optical system and method for non-invasive imaging of biological tissue
US6397099B1 (en) 1992-05-18 2002-05-28 Non-Invasive Technology, Inc. Non-invasive imaging of biological tissue
US5987346A (en) * 1993-02-26 1999-11-16 Benaron; David A. Device and method for classification of tissue
US5803909A (en) * 1994-10-06 1998-09-08 Hitachi, Ltd. Optical system for measuring metabolism in a body and imaging method
WO1996020638A1 (en) * 1995-01-03 1996-07-11 Non-Invasive Technology, Inc. Optical coupler for in vivo examination of biological tissue
US6618614B1 (en) 1995-01-03 2003-09-09 Non-Invasive Technology, Inc. Optical examination device, system and method
US20050043596A1 (en) * 1996-07-12 2005-02-24 Non-Invasive Technology, Inc., A Delaware Corporation Optical examination device, system and method
US6152876A (en) * 1997-04-18 2000-11-28 Rio Grande Medical Technologies, Inc. Method for non-invasive blood analyte measurement with improved optical interface
US6240309B1 (en) * 1995-10-06 2001-05-29 Hitachi, Ltd. Optical measurement instrument for living body
US20060184047A1 (en) * 1995-11-17 2006-08-17 Yuichi Yamashita Optical measurement instrument for living body
WO1998044839A1 (en) * 1997-04-03 1998-10-15 National Research Council Of Canada Method of assessing tissue viability using near-infrared spectroscopy
EP0925016B1 (en) 1997-05-09 2004-07-28 Koninklijke Philips Electronics N.V. Device for localizing an object in a turbid medium
US6675035B1 (en) * 1997-06-20 2004-01-06 Imaging Diagnostic Systems, Inc. Phantom for optical and magnetic resonance imaging quality control
WO1999040841A1 (en) 1998-02-11 1999-08-19 Non-Invasive Technology, Inc. Imaging and characterization of brain tissue
DE69934482T2 (en) 1998-02-11 2007-09-27 Non-Invasive Technology, Inc. PROOF, PICTURE AND IDENTIFICATION OF BREAST ENVELOPES
EP1054620B1 (en) 1998-02-13 2010-01-27 Non-Invasive Technology, Inc. Transabdominal examination, monitoring and imaging of tissue
JP4006826B2 (en) 1998-04-28 2007-11-14 株式会社日立製作所 Biological light measurement device
US6592847B1 (en) * 1998-05-14 2003-07-15 The General Hospital Corporation Intramolecularly-quenched near infrared flourescent probes
EP1085835A4 (en) * 1998-06-19 2002-10-30 Uab Research Foundation Oximetric tonometer with intracranial pressure monitoring capability
US6668187B1 (en) 1998-07-30 2003-12-23 Yissum Research Development Company Of The Hebrew University Of Jerusalem Optical mammography
US6949081B1 (en) 1998-08-26 2005-09-27 Non-Invasive Technology, Inc. Sensing and interactive drug delivery
WO2000013578A1 (en) * 1998-09-03 2000-03-16 Hypermed Imaging, Inc. Infrared endoscopic balloon probes
US8024027B2 (en) 1998-09-03 2011-09-20 Hyperspectral Imaging, Inc. Infrared endoscopic balloon probes
US6741884B1 (en) 1998-09-03 2004-05-25 Hypermed, Inc. Infrared endoscopic balloon probes
JP2002527134A (en) * 1998-10-13 2002-08-27 ソマネティクス コーポレイション Multi-channel non-invasive tissue oximeter
DE69929380T2 (en) 1998-12-07 2006-08-31 Hitachi, Ltd. Device for controlling plants by means of body signals
US7047054B2 (en) * 1999-03-12 2006-05-16 Cas Medical Systems, Inc. Laser diode optical transducer assembly for non-invasive spectrophotometric blood oxygenation monitoring
EP1079725B1 (en) 1999-03-23 2007-05-23 Koninklijke Philips Electronics N.V. Device for localizing an object in a turbid medium
US7039454B1 (en) * 1999-03-29 2006-05-02 Hitachi Medical Corporation Biological optical measuring instrument
IL129398A (en) * 1999-04-12 2005-05-17 Israel Atomic Energy Comm Metabolism monitoring or body organs
US6167297A (en) * 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
AU4058999A (en) * 1999-06-03 2000-12-28 Hamamatsu Photonics K.K. Optical ct device and method of image reformation
US7840257B2 (en) 2003-01-04 2010-11-23 Non Invasive Technology, Inc. Examination of biological tissue using non-contact optical probes
US7904139B2 (en) 1999-08-26 2011-03-08 Non-Invasive Technology Inc. Optical examination of biological tissue using non-contact irradiation and detection
DE60031551T2 (en) * 1999-08-31 2007-08-23 Nir Diagnostics Inc., Waterloo DEVICE FOR VERIFYING THE ACCURACY OF A SPECTRAL ANALYZER
CA2384813C (en) * 1999-09-14 2014-01-21 Randall L. Barbour Method and system for imaging the dynamics of scattering medium
US7280866B1 (en) 1999-10-06 2007-10-09 National Research Council Of Canada Non-invasive screening of skin diseases by visible/near-infrared spectroscopy
DE19954756A1 (en) * 1999-11-17 2001-05-31 Odim Gmbh Device and method for examining biological tissue
US7006676B1 (en) 2000-01-21 2006-02-28 Medical Optical Imaging, Inc. Method and apparatus for detecting an abnormality within a host medium utilizing frequency-swept modulation diffusion tomography
CA2398278C (en) 2000-01-27 2012-05-15 National Research Council Of Canada Visible-near infrared spectroscopy in burn injury assessment
DE10004989B4 (en) * 2000-02-04 2006-11-02 Siemens Ag Method and device for arthritis diagnosis
US6597931B1 (en) 2000-09-18 2003-07-22 Photonify Technologies, Inc. System and method for absolute oxygen saturation
US6801648B2 (en) 2000-08-04 2004-10-05 Xuefeng Cheng Optical imaging system with symmetric optical probe
US6587703B2 (en) 2000-09-18 2003-07-01 Photonify Technologies, Inc. System and method for measuring absolute oxygen saturation
US6516209B2 (en) 2000-08-04 2003-02-04 Photonify Technologies, Inc. Self-calibrating optical imaging system
US6719686B2 (en) * 2000-08-30 2004-04-13 Mallinckrodt, Inc. Fetal probe having an optical imaging device
US7383076B2 (en) * 2000-11-27 2008-06-03 The General Hospital Corporation Fluorescence-mediated molecular tomography
US6826424B1 (en) * 2000-12-19 2004-11-30 Haishan Zeng Methods and apparatus for fluorescence and reflectance imaging and spectroscopy and for contemporaneous measurements of electromagnetic radiation with multiple measuring devices
US20030044353A1 (en) * 2001-01-05 2003-03-06 Ralph Weissleder Activatable imaging probes
DE10109539A1 (en) * 2001-02-28 2002-09-12 Siemens Ag Device for examining tissue with light
WO2002097404A1 (en) * 2001-05-30 2002-12-05 Sciperio, Inc. System, method, and apparatus for non-intrusively determining concentration of a solute in a solution
US6659941B2 (en) * 2001-06-19 2003-12-09 Mallinckrodt, Inc. Balloon assisted endoscope for viewing a fetus during delivery
US7047057B2 (en) * 2001-07-16 2006-05-16 Art. Advanced Research Technologies Inc. Simultaneous multiwavelength TPSF-based optical imaging
WO2004065943A1 (en) * 2003-01-22 2004-08-05 Art, Advanced Research Technologies, Inc. Simultaneous acquisition of different time-gates in tpsf-based optical imaging
US20030062485A1 (en) * 2001-09-28 2003-04-03 Fernandez Salvador M. Compact multiwavelength phase fluorometer
US20050107709A1 (en) * 2002-04-02 2005-05-19 Technische Universitat Dresden Method and arrangement for optically measuring swelling of the nose
EP1514093B1 (en) 2002-06-04 2021-04-28 Visen Medical, Inc. Imaging volumes with arbitrary geometries in non-contact tomography
AU2003254135B2 (en) 2002-07-26 2006-11-16 Cas Medical Systems, Inc. Method for spectrophotometric blood oxygenation monitoring
US7810359B2 (en) 2002-10-01 2010-10-12 Nellcor Puritan Bennett Llc Headband with tension indicator
US7698909B2 (en) 2002-10-01 2010-04-20 Nellcor Puritan Bennett Llc Headband with tension indicator
US7647091B2 (en) * 2003-02-05 2010-01-12 The General Hospital Corporation Method and system for free space optical tomography of diffuse media
JP2006516920A (en) * 2003-02-06 2006-07-13 コーニンクレッカ　フィリップス　エレクトロニクス　エヌ　ヴィ Apparatus and method for blood analysis
US7047056B2 (en) * 2003-06-25 2006-05-16 Nellcor Puritan Bennett Incorporated Hat-based oximeter sensor
US6949072B2 (en) * 2003-09-22 2005-09-27 Infraredx, Inc. Devices for vulnerable plaque detection
US8412297B2 (en) 2003-10-01 2013-04-02 Covidien Lp Forehead sensor placement
KR100561857B1 (en) * 2004-01-12 2006-03-16 삼성전자주식회사 Device and method for detecting acupoints
US7491169B2 (en) 2004-03-22 2009-02-17 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Ultrasonic apparatus and method to assess compartment syndrome
US8060172B2 (en) * 2004-03-29 2011-11-15 Olympus Corporation In-vivo information measurement apparatus
US7570979B2 (en) * 2004-03-30 2009-08-04 Philip George Cooper Methods and apparatus for patient monitoring
US7313425B2 (en) * 2004-07-08 2007-12-25 Orsense Ltd. Device and method for non-invasive optical measurements
US7381186B2 (en) * 2004-08-02 2008-06-03 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method and apparatus to assess compartment syndrome
US20060094940A1 (en) * 2004-09-21 2006-05-04 Art, Advanced Research Technologies, Inc. Method for selecting wavelengths for optical data acquisition
US8062224B2 (en) * 2004-10-28 2011-11-22 Uab Vittamed Method and apparatus for non-invasive continuous monitoring of cerebrovascular autoregulation state
US7298009B2 (en) * 2005-02-01 2007-11-20 Infineon Technologies Ag Semiconductor method and device with mixed orientation substrate
WO2006124696A1 (en) * 2005-05-13 2006-11-23 Children's Hospital Medical Center Multi-wavelength spatial domain near infrared oximeter to detect cerebral hypoxia-ischemia
US7736382B2 (en) 2005-09-09 2010-06-15 Lockheed Martin Corporation Apparatus for optical stimulation of nerves and other animal tissue
US20070093708A1 (en) * 2005-10-20 2007-04-26 Benaron David A Ultra-high-specificity device and methods for the screening of in-vivo tumors
US8792978B2 (en) 2010-05-28 2014-07-29 Lockheed Martin Corporation Laser-based nerve stimulators for, E.G., hearing restoration in cochlear prostheses and method
US7802690B2 (en) * 2005-10-24 2010-09-28 Portola Packaging, Inc. Closure having expanded peripheral surface
US20080077200A1 (en) * 2006-09-21 2008-03-27 Aculight Corporation Apparatus and method for stimulation of nerves and automated control of surgical instruments
US8012189B1 (en) 2007-01-11 2011-09-06 Lockheed Martin Corporation Method and vestibular implant using optical stimulation of nerves
US8475506B1 (en) 2007-08-13 2013-07-02 Lockheed Martin Corporation VCSEL array stimulator apparatus and method for light stimulation of bodily tissues
US8945197B1 (en) 2005-10-24 2015-02-03 Lockheed Martin Corporation Sight-restoring visual prosthetic and method using infrared nerve-stimulation light
US8956396B1 (en) 2005-10-24 2015-02-17 Lockheed Martin Corporation Eye-tracking visual prosthetic and method
US8709078B1 (en) 2011-08-03 2014-04-29 Lockheed Martin Corporation Ocular implant with substantially constant retinal spacing for transmission of nerve-stimulation light
CN101312682B (en) * 2005-11-23 2011-05-25 皇家飞利浦电子股份有限公司 Method and device for optical imaging of a turbid medium
US7559945B2 (en) 2006-01-13 2009-07-14 Clarimedix Inc. Multi-spectral photon therapy device and methods of use
WO2007087560A2 (en) * 2006-01-26 2007-08-02 The Board Of Trustees Of The University Of Illinois Stroke inducing and monitoring system and method for using the same
WO2007109124A2 (en) * 2006-03-16 2007-09-27 The Trustees Of Boston University Electro-optical sensor for peripheral nerves
US20070282404A1 (en) * 2006-04-10 2007-12-06 University Of Rochester Side-firing linear optic array for interstitial optical therapy and monitoring using compact helical geometry
BRPI0716558A2 (en) * 2006-09-07 2013-09-24 Koninkl Philips Electronics Nv device for imaging an interior of a medium, and, receptacle
US8498699B2 (en) 2008-10-03 2013-07-30 Lockheed Martin Company Method and nerve stimulator using simultaneous electrical and optical signals
US8996131B1 (en) 2006-09-28 2015-03-31 Lockheed Martin Corporation Apparatus and method for managing chronic pain with infrared light sources and heat
US8116852B2 (en) 2006-09-29 2012-02-14 Nellcor Puritan Bennett Llc System and method for detection of skin wounds and compartment syndromes
US20100002233A1 (en) * 2006-10-30 2010-01-07 Koninklijke Philips Electronics N.V. Imaging of turbid medium
CN101534703A (en) * 2006-11-17 2009-09-16 皇家飞利浦电子股份有限公司 Device for imaging an interior of a turbid medium
US7936459B1 (en) * 2006-11-21 2011-05-03 David Coombs Apparatus with probe
WO2008080083A2 (en) * 2006-12-22 2008-07-03 Washington University High performance imaging system for diffuse optical tomography and associated method of use
US7883536B1 (en) 2007-01-19 2011-02-08 Lockheed Martin Corporation Hybrid optical-electrical probes
US8100834B2 (en) 2007-02-27 2012-01-24 J&M Shuler, Inc. Method and system for monitoring oxygenation levels of a compartment for detecting conditions of a compartment syndrome
US8639309B2 (en) 2007-07-31 2014-01-28 J&M Shuler, Inc. Method and system for monitoring oxygenation levels of compartments and tissue
US20080228053A1 (en) * 2007-03-15 2008-09-18 Shih-Ping Wang Method and system for cerebral oxygenation level monitoring
US9226731B2 (en) * 2007-05-21 2016-01-05 The Board Of Regents Of The University Of Texas System Optically guided needle biopsy system using multi-modal spectroscopy in combination with a transrectal ultrasound probe
ATE548637T1 (en) * 2007-09-24 2012-03-15 Univ Potsdam MEASURING ARRANGEMENT FOR AN OPTICAL SPECTROMETER
US9488574B2 (en) * 2007-10-19 2016-11-08 Koninklijke Philips N.V. Device for imaging the interior of an optically turbid medium and receptacle unit for such a device
JP5420163B2 (en) * 2007-10-24 2014-02-19 浜松ホトニクス株式会社 Biological measuring device
US8840654B2 (en) 2011-07-22 2014-09-23 Lockheed Martin Corporation Cochlear implant using optical stimulation with encoded information designed to limit heating effects
US8380272B2 (en) * 2007-12-21 2013-02-19 Covidien Lp Physiological sensor
ES2658852T3 (en) 2008-01-18 2018-03-12 Visen Medical, Inc. Fluorescent Imaging Agents
DE102008011013B4 (en) * 2008-02-25 2014-11-13 Mevitec Gmbh Method and device for complex metabolic analysis
US8243071B2 (en) * 2008-02-29 2012-08-14 Microsoft Corporation Modeling and rendering of heterogeneous translucent materials using the diffusion equation
US20090234245A1 (en) * 2008-03-17 2009-09-17 O2 Medtech, Inc. Non-invasive monitoring of intracranial pressure
US9480425B2 (en) * 2008-04-17 2016-11-01 Washington University Task-less optical mapping of dynamic brain function using resting state functional connectivity
CA2891990C (en) 2008-05-20 2022-07-26 Ralph Sebastian Dacosta Device and method for fluorescence-based imaging and monitoring
US8577431B2 (en) 2008-07-03 2013-11-05 Cercacor Laboratories, Inc. Noise shielding for a noninvasive device
US20100016731A1 (en) * 2008-07-15 2010-01-21 Cardiox Corporation Hemodynamic Detection of Circulatory Anomalies
EP2328480B1 (en) 2008-07-18 2016-01-06 University Of Rochester Low-cost device for c-scan photoacoustic imaging
DE102008050109B4 (en) * 2008-07-21 2010-06-17 Ancosys Gmbh Optical sensor
US8630691B2 (en) 2008-08-04 2014-01-14 Cercacor Laboratories, Inc. Multi-stream sensor front ends for noninvasive measurement of blood constituents
MX349711B (en) 2008-09-18 2017-08-09 Cedars Sinai Medical Center Optical method for the detection of alzheimer's disease.
US8257274B2 (en) 2008-09-25 2012-09-04 Nellcor Puritan Bennett Llc Medical sensor and technique for using the same
US8364220B2 (en) 2008-09-25 2013-01-29 Covidien Lp Medical sensor and technique for using the same
JP5770090B2 (en) * 2008-09-26 2015-08-26 コーニンクレッカ フィリップス エヌ ヴェ Variable volume detection chamber
WO2010058339A2 (en) * 2008-11-21 2010-05-27 Koninklijke Philips Electronics N.V. Imaging a turbid medium
WO2010061339A1 (en) * 2008-11-26 2010-06-03 Koninklijke Philips Electronics N.V. Device and method for optically examining the interior of a turbid medium
US8515515B2 (en) 2009-03-25 2013-08-20 Covidien Lp Medical sensor with compressible light barrier and technique for using the same
US8781548B2 (en) 2009-03-31 2014-07-15 Covidien Lp Medical sensor with flexible components and technique for using the same
US20120095305A1 (en) * 2009-06-15 2012-04-19 O2 Medtech, Inc. Spectrophotometric Monitoring Of Multiple Layer Tissue Structures
EP2451344B1 (en) * 2009-07-10 2019-02-20 Cas Medical Systems, Inc. Method for spectrophotometric blood oxygenation monitoring of the lower gastrointestinal tract
US8688183B2 (en) 2009-09-03 2014-04-01 Ceracor Laboratories, Inc. Emitter driver for noninvasive patient monitor
FR2950431B1 (en) 2009-09-24 2011-12-09 Commissariat Energie Atomique DEVICE AND METHOD FOR SPATIAL RECONSTRUCTION OF FLUORESCENCE CARTOGRAPHY
FR2951283B1 (en) * 2009-10-08 2013-02-15 Commissariat Energie Atomique METHOD AND DEVICE FOR DIFFUSED EXCITATION IN IMAGING
CN102883658B (en) * 2009-11-19 2016-06-22 调节成像公司 The method and apparatus analyzing turbid media for using structured lighting to detect via unit piece
DE102010014702A1 (en) * 2010-04-12 2011-10-13 Mbr Optikal Systems Gmbh & Co. Kg Measuring arrangement for recording a spectrum, in particular on vital tissue
US11490957B2 (en) 2010-06-16 2022-11-08 Biosense Webster (Israel) Ltd. Spectral sensing of ablation
US10314650B2 (en) 2010-06-16 2019-06-11 Biosense Webster (Israel) Ltd. Spectral sensing of ablation
US8648321B2 (en) 2010-07-05 2014-02-11 Emz-Hanauer Gmbh & Co. Kgaa Optical sensor for use in a domestic washing machine or dishwasher
DE102010026068B4 (en) 2010-07-05 2017-09-28 Emz-Hanauer Gmbh & Co. Kgaa Optical sensor, in particular for installation in a washing machine or a dishwasher of household equipment
US8798703B2 (en) * 2010-09-07 2014-08-05 Cnsystems Medizintechnik Ag Disposable and detachable sensor for continuous non-invasive arterial blood pressure monitoring
JP5710767B2 (en) 2010-09-28 2015-04-30 マシモ コーポレイション Depth of consciousness monitor including oximeter
US9775545B2 (en) 2010-09-28 2017-10-03 Masimo Corporation Magnetic electrical connector for patient monitors
CN103282764A (en) * 2010-10-29 2013-09-04 尼尔科学公司 Method and apparatus for analyte detection
EP2635185A4 (en) 2010-11-03 2014-12-24 Univ Washington Through Its Ct For Com Ization Determination of tissue oxygenation in vivo
FR2968921B1 (en) 2010-12-15 2013-01-11 Commissariat Energie Atomique METHOD FOR LOCATING AN OPTICAL MARKER IN A DIFFUSING MEDIUM
CN102551736A (en) * 2012-01-19 2012-07-11 西北工业大学 Light sensing system
EP2819573B1 (en) * 2012-02-27 2017-07-05 APD Advanced Perfusion Diagnostics Apparatus and method for measuring blood flow within the gastrointestinal tract
WO2013134949A1 (en) * 2012-03-16 2013-09-19 西安电子科技大学 Device and method for endoscopic x ray luminescence tomography imaging
WO2013186780A1 (en) 2012-06-13 2013-12-19 Hadasit Medical Research Services And Development Ltd. Devices and methods for detection of internal bleeding and hematoma
US20140046170A1 (en) * 2012-08-07 2014-02-13 Chia-Wei Sun Brain volumetric measuring method and system using the same
US20140051975A1 (en) * 2012-08-15 2014-02-20 Aspect Imaging Ltd. Multiple heterogeneous imaging systems for clinical and preclinical diagnosis
CN105190308B (en) 2012-11-07 2021-05-28 调节成像公司 Device and method for measuring turbid samples
US9256963B2 (en) 2013-04-09 2016-02-09 Elc Management Llc Skin diagnostic and image processing systems, apparatus and articles
US9101320B2 (en) 2013-04-09 2015-08-11 Elc Management Llc Skin diagnostic and image processing methods
PT2999402T (en) * 2013-05-22 2023-03-07 Luciole Medical AG Measurement system and method for measuring parameters in a body tissue
DE102013010611A1 (en) * 2013-06-25 2015-01-08 Sms Swiss Medical Sensor Ag Measuring device and measuring method for measuring raw data for determining a blood parameter, in particular for noninvasive determination of the D-glucose concentration
WO2015010709A1 (en) * 2013-07-22 2015-01-29 Sentec Ag Sensor for detection of gas and method for detection of gas
USD763938S1 (en) 2014-04-02 2016-08-16 Cephalogics, LLC Optical sensor array
USD763939S1 (en) 2014-04-02 2016-08-16 Cephalogics, LLC Optical sensor array liner with optical sensor array pad
DE102014107342B4 (en) 2014-05-24 2023-05-04 Frank Braun Device and method for detecting cancerous tumors and other tissue changes
DK3171765T3 (en) 2014-07-24 2021-11-01 Univ Health Network COLLECTION AND ANALYSIS OF DATA FOR DIAGNOSTIC PURPOSES
WO2016057553A1 (en) 2014-10-07 2016-04-14 Masimo Corporation Modular physiological sensors
JP6555503B2 (en) * 2015-01-13 2019-08-07 株式会社リコー Optical sensor, optical inspection apparatus, and optical property detection method
US10499838B2 (en) 2015-04-24 2019-12-10 Drexel University Non-invasive brain water monitoring device for cerebral edema and cerebral autoregulation monitoring system and method
ES2588017B1 (en) * 2015-04-27 2017-08-02 Universidad Miguel Hernández De Elche A device suitable for the collection of data in a record of neuronal activity
US10448871B2 (en) 2015-07-02 2019-10-22 Masimo Corporation Advanced pulse oximetry sensor
US10105090B2 (en) * 2016-10-13 2018-10-23 Photon Migration Technologies Corp. Method for representations of network-dependent features of the hemoglobin signal in living tissues for detection of breast cancer and other applications
DE102017116308A1 (en) * 2017-07-19 2019-01-24 Osram Opto Semiconductors Gmbh Optoelectronic sensor
WO2019051223A1 (en) * 2017-09-07 2019-03-14 Arizona Board Of Regents On Behalf Of The University Of Arizona Imaging electrical current patterns generated by a medical device
EP3473172A1 (en) 2017-10-20 2019-04-24 Universität Zürich Apparatus for measuring optical parameters in scattering media
WO2019231443A1 (en) * 2018-05-30 2019-12-05 Chi-Hua Foundation Marker and method for evaluating cognitive dysfunction
US11864909B2 (en) 2018-07-16 2024-01-09 Bbi Medical Innovations, Llc Perfusion and oxygenation measurement
CN109106376B (en) * 2018-09-20 2022-04-19 京东方科技集团股份有限公司 Method and device for detecting concentration of total hemoglobin in blood
CA3168046A1 (en) * 2021-04-11 2022-10-11 Alio, Inc. Systems and methods measuring biological metrics and blood vessel geometry using a multiple optical path photoplethysmography device
WO2024011092A2 (en) * 2022-07-05 2024-01-11 Tomov Martin Lyubomirov Dental robot helmet

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3068742A (en) * 1959-06-15 1962-12-18 American Optical Corp Means for performing colorimetry
US3412729A (en) * 1965-08-30 1968-11-26 Nasa Usa Method and apparatus for continuously monitoring blood oxygenation, blood pressure, pulse rate and the pressure pulse curve utilizing an ear oximeter as transducer
US3461856A (en) * 1965-10-23 1969-08-19 American Optical Corp Oximeters
US3638640A (en) * 1967-11-01 1972-02-01 Robert F Shaw Oximeter and method for in vivo determination of oxygen saturation in blood using three or more different wavelengths
US3709612A (en) * 1971-03-10 1973-01-09 Miles Lab Apparatus for measuring reflected light under stabilized light source conditions
US3866599A (en) * 1972-01-21 1975-02-18 Univ Washington Fiberoptic catheter
CH581836A5 (en) * 1974-08-20 1976-11-15 Contraves Ag
JPS5725217B2 (en) * 1974-10-14 1982-05-28
CA1037285A (en) * 1975-04-30 1978-08-29 Glenfield Warner Ear oximetry process and apparatus
US4119406A (en) * 1976-05-06 1978-10-10 Miles Laboratories, Inc. Calibration apparatus
US4167331A (en) * 1976-12-20 1979-09-11 Hewlett-Packard Company Multi-wavelength incremental absorbence oximeter
US4086652A (en) * 1977-01-19 1978-04-25 Block Engineering, Inc. Method and apparatus for analyzing a time-dependent phenomenon
US4281645A (en) * 1977-06-28 1981-08-04 Duke University, Inc. Method and apparatus for monitoring metabolism in body organs
US4162405A (en) * 1978-05-23 1979-07-24 Britton Chance Flying spot fluoro-meter for oxidized flavoprotein and reduced pyridine nucleotide
US4416285A (en) * 1978-11-29 1983-11-22 Oximetrix, Inc. Improved optical catheter and method for making same
US4515165A (en) * 1980-02-04 1985-05-07 Energy Conversion Devices, Inc. Apparatus and method for detecting tumors
US4485820A (en) * 1982-05-10 1984-12-04 The Johns Hopkins University Method and apparatus for the continuous monitoring of hemoglobin saturation in the blood of premature infants
DE3323365C2 (en) * 1982-09-04 1994-10-20 Gsf Forschungszentrum Umwelt Method and device for illuminating cavities
US4570638A (en) * 1983-10-14 1986-02-18 Somanetics Corporation Method and apparatus for spectral transmissibility examination and analysis
IT1206462B (en) * 1984-08-07 1989-04-27 Anic Spa MULTI-WAVE LENGTH PULSED LIGHT PHOTOMETER FOR NON-INVASIVE MONITORING.
DD227044B1 (en) * 1984-10-11 1990-10-10 Akad Wissenschaften Ddr DEVICE FOR DETECTING THE METABOLISM CONDITION OF LIVING ORGANS
US5106387A (en) * 1985-03-22 1992-04-21 Massachusetts Institute Of Technology Method for spectroscopic diagnosis of tissue
US4824242A (en) * 1986-09-26 1989-04-25 Sensormedics Corporation Non-invasive oximeter and method
DK168849B1 (en) * 1987-02-23 1994-06-27 Sumitomo Electric Industries Apparatus for measuring tissue metabolism
GB8709406D0 (en) * 1987-04-21 1987-05-28 Aberdeen University Of Univers Examining body of living tissues
JPS63277039A (en) * 1987-05-08 1988-11-15 Hamamatsu Photonics Kk Diagnostic apparatus
US4805623A (en) * 1987-09-04 1989-02-21 Vander Corporation Spectrophotometric method for quantitatively determining the concentration of a dilute component in a light- or other radiation-scattering environment
US4846183A (en) * 1987-12-02 1989-07-11 The Boc Group, Inc. Blood parameter monitoring apparatus and methods
US4800885A (en) * 1987-12-02 1989-01-31 The Boc Group, Inc. Blood constituent monitoring apparatus and methods with frequency division multiplexing
JP2882797B2 (en) * 1988-02-24 1999-04-12 コーリン電子株式会社 Peripheral resistance test output device
US5596987A (en) * 1988-11-02 1997-01-28 Noninvasive Technology, Inc. Optical coupler for in vivo examination of biological tissue
US4972331A (en) * 1989-02-06 1990-11-20 Nim, Inc. Phase modulated spectrophotometry
US5402778A (en) * 1993-01-19 1995-04-04 Nim Incorporated Spectrophotometric examination of tissue of small dimension
US5555885A (en) * 1988-12-21 1996-09-17 Non-Invasive Technology, Inc. Examination of breast tissue using time-resolved spectroscopy
US5187672A (en) * 1989-02-06 1993-02-16 Nim Incorporated Phase modulation spectroscopic system
US5119815A (en) 1988-12-21 1992-06-09 Nim, Incorporated Apparatus for determining the concentration of a tissue pigment of known absorbance, in vivo, using the decay characteristics of scintered electromagnetic radiation
US5386827A (en) 1993-03-30 1995-02-07 Nim Incorporated Quantitative and qualitative in vivo tissue examination using time resolved spectroscopy
US5090415A (en) * 1989-02-14 1992-02-25 Hamamatsu Photonics Kabushiki Kaisha Examination apparatus
US4945239A (en) * 1989-03-29 1990-07-31 Center For Innovative Technology Early detection of breast cancer using transillumination
JP2798450B2 (en) * 1989-12-08 1998-09-17 株式会社日立製作所 Biological measurement device
EP0497021A1 (en) * 1991-01-31 1992-08-05 Hamamatsu Photonics K.K. Oximeter with monitor
US5300097A (en) * 1991-02-13 1994-04-05 Lerner Ethan A Fiber optic psoriasis treatment device
EP0591289B1 (en) * 1991-05-16 1999-07-07 Non-Invasive Technology, Inc. Hemoglobinometers and the like for measuring the metabolic condition of a subject
US5398685A (en) * 1992-01-10 1995-03-21 Wilk; Peter J. Endoscopic diagnostic system and associated method
US6397099B1 (en) * 1992-05-18 2002-05-28 Non-Invasive Technology, Inc. Non-invasive imaging of biological tissue
JP2556433Y2 (en) * 1992-05-29 1997-12-03 株式会社島津製作所 Biological photometric device
US5355880A (en) * 1992-07-06 1994-10-18 Sandia Corporation Reliable noninvasive measurement of blood gases
EP0614645A4 (en) * 1992-08-31 1996-04-03 Hitachi Ltd Optical ct apparatus.
US5420607A (en) * 1992-09-02 1995-05-30 Miller; Robert F. Electronic paintbrush and color palette
IL107396A (en) * 1992-11-09 1997-02-18 Boehringer Mannheim Gmbh Method and apparatus for analytical determination of glucose in a biological matrix
US5358503A (en) * 1994-01-25 1994-10-25 Bertwell Dale E Photo-thermal therapeutic device and method
DE4410888A1 (en) * 1994-03-29 1995-10-05 Zeiss Carl Jena Gmbh Apparatus for irradiating human tissue using multi-wavelength IR light
US5625458A (en) * 1994-11-10 1997-04-29 Research Foundation Of City College Of New York Method and system for imaging objects in turbid media using diffusive fermat photons
US5706821A (en) * 1994-12-30 1998-01-13 Hamamatsu Photonics K.K. Spectroscopic method for quantitatively determining the change of concentration of a light or other radiation absorbing compound in a medium which is interrogated through an intervening medium
WO1996020638A1 (en) * 1995-01-03 1996-07-11 Non-Invasive Technology, Inc. Optical coupler for in vivo examination of biological tissue
US5655530A (en) * 1995-08-09 1997-08-12 Rio Grande Medical Technologies, Inc. Method for non-invasive blood analyte measurement with improved optical interface

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8060189B2 (en) 2005-05-06 2011-11-15 Infrascan, Inc. System and method for detection of hematoma

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