CA2213719A1 - Transparent rapid-release preparation of non-steroid analgesics - Google Patents

Transparent rapid-release preparation of non-steroid analgesics

Info

Publication number
CA2213719A1
CA2213719A1 CA002213719A CA2213719A CA2213719A1 CA 2213719 A1 CA2213719 A1 CA 2213719A1 CA 002213719 A CA002213719 A CA 002213719A CA 2213719 A CA2213719 A CA 2213719A CA 2213719 A1 CA2213719 A1 CA 2213719A1
Authority
CA
Canada
Prior art keywords
release preparation
rapid
analgesics
transparent
steroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002213719A
Other languages
French (fr)
Other versions
CA2213719C (en
Inventor
Jorg Breitenbach
Axel Sanner
Joerg Rosenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2213719A1 publication Critical patent/CA2213719A1/en
Application granted granted Critical
Publication of CA2213719C publication Critical patent/CA2213719C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Abstract

Transparent rapid-release active agent preparations obtainable by the extrusion of melts containing non-steroid analgesics, homopolymers of N-vinyl pyrrolidone, saccharides or sugar alcohols and sodium or potassium salts.
CA002213719A 1995-03-21 1996-03-09 Transparent rapid-release preparation of non-steroid analgesics Expired - Fee Related CA2213719C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19509805A DE19509805A1 (en) 1995-03-21 1995-03-21 Transparent, fast-release formulations of nonsteroidal analgesics
DE19509805.6 1995-03-21
PCT/EP1996/001021 WO1996029053A1 (en) 1995-03-21 1996-03-09 Transparent rapid-release preparations of non-steroid analgesics

Publications (2)

Publication Number Publication Date
CA2213719A1 true CA2213719A1 (en) 1996-09-26
CA2213719C CA2213719C (en) 2005-01-11

Family

ID=7757016

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002213719A Expired - Fee Related CA2213719C (en) 1995-03-21 1996-03-09 Transparent rapid-release preparation of non-steroid analgesics

Country Status (21)

Country Link
US (1) US6063821A (en)
EP (1) EP0817612B1 (en)
JP (1) JPH11502209A (en)
KR (1) KR19980703160A (en)
AT (1) ATE196078T1 (en)
AU (1) AU5105396A (en)
BR (1) BR9607867A (en)
CA (1) CA2213719C (en)
CZ (1) CZ286011B6 (en)
DE (2) DE19509805A1 (en)
DK (1) DK0817612T3 (en)
EA (1) EA000434B1 (en)
ES (1) ES2151150T3 (en)
GR (1) GR3034441T3 (en)
HU (1) HU221614B (en)
IL (1) IL117531A (en)
NO (1) NO318236B1 (en)
PT (1) PT817612E (en)
TW (1) TW416850B (en)
WO (1) WO1996029053A1 (en)
ZA (1) ZA962241B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19602206A1 (en) * 1996-01-23 1997-07-24 Basf Ag Preparations of nonsteroidal analgesics
EP0956004B1 (en) 1996-11-15 2004-09-15 MERCK PATENT GmbH Method for producing shaped and unshaped polyol masses and compositions obtained by the process
DE69834255T2 (en) * 1997-07-25 2006-09-28 Alpex Pharma S.A. PROCESS FOR PRODUCING A GRANULATE, SUITABLE FOR THE PRODUCTION OF FAST-RELEASING, IN THE MOUSE OF SOLUBLE TABLETS
EP1175205B1 (en) * 1999-11-12 2006-06-14 Abbott Laboratories Solid dispersion comprising ritonavir, fenofibrate or griseofulvin
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
ES2170645B1 (en) * 2000-03-23 2003-10-01 Alcala Farma S L Lab SOLID PHARMACEUTICAL FORM OF ORAL ADMINISTRATION OF A WATER SOLUBLE METAMIZOL SALT, PROCEDURE FOR OBTAINING AND FORM OF PRESENTATION OF THE PHARMACEUTICAL FORM.
DE10026698A1 (en) * 2000-05-30 2001-12-06 Basf Ag Self-emulsifying active ingredient formulation and use of this formulation
DE10031044A1 (en) * 2000-06-26 2002-01-03 Bayer Ag Endoparasiticidal agents for voluntary oral ingestion by animals
GB0102342D0 (en) 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7842308B2 (en) 2001-01-30 2010-11-30 Smithkline Beecham Limited Pharmaceutical formulation
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
EP1530457B1 (en) 2002-08-12 2009-09-09 Bend Research, Inc. Pharmaceutical compositions of drugs in semi-ordered form and polymers
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
GB0403098D0 (en) 2004-02-12 2004-03-17 Euro Celtique Sa Extrusion
PE20060003A1 (en) * 2004-03-12 2006-03-01 Smithkline Beecham Plc POLYMERIC PHARMACEUTICAL FORMULATION FOR INJECTION MOLDING
WO2007012022A2 (en) * 2005-07-18 2007-01-25 Horizon Therapeutics, Inc. Unit dose form with ibuprofen-famotidine admixture
GB2447898B (en) * 2007-03-24 2011-08-17 Reckitt Benckiser Healthcare A tablet having improved stability with at least two actives
JP2011503048A (en) 2007-11-08 2011-01-27 グラクソ グループ リミテッド Pharmaceutical formulation
WO2009150228A2 (en) * 2008-06-13 2009-12-17 Glaxo Group Limited Pharmaceutical formulations
JP5499703B2 (en) * 2009-12-28 2014-05-21 ライオン株式会社 Formulation containing ibuprofen
US20110236666A1 (en) * 2010-03-26 2011-09-29 Hall Mark J Melt-extruded film
WO2011119287A1 (en) * 2010-03-26 2011-09-29 Dow Global Technologies Llc Melt-extruded film

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3612212A1 (en) * 1986-04-11 1987-10-15 Basf Ag METHOD FOR PRODUCING SOLID PHARMACEUTICAL FORMS
DE3830355A1 (en) * 1988-09-07 1990-03-15 Basf Ag METHOD FOR PRODUCING PHARMACEUTICAL TABLETS
ATE180668T1 (en) * 1992-12-01 1999-06-15 Spirig Ag MEDICINAL PRODUCTS CONTAINING S(+)-IBUPROFEN
GB9302259D0 (en) * 1993-02-05 1993-03-24 Cerestar Holding Bv Starch based material
DE19509807A1 (en) * 1995-03-21 1996-09-26 Basf Ag Process for the preparation of active substance preparations in the form of a solid solution of the active substance in a polymer matrix, and active substance preparations produced using this method
DE4418837A1 (en) * 1994-05-30 1995-12-07 Bayer Ag Thermal granulation process

Also Published As

Publication number Publication date
EA199700247A1 (en) 1998-02-26
BR9607867A (en) 1998-06-30
DK0817612T3 (en) 2000-11-20
NO974338L (en) 1997-09-19
EA000434B1 (en) 1999-08-26
IL117531A (en) 2000-01-31
NO318236B1 (en) 2005-02-21
NO974338D0 (en) 1997-09-19
EP0817612A1 (en) 1998-01-14
WO1996029053A1 (en) 1996-09-26
CZ286011B6 (en) 1999-12-15
DE19509805A1 (en) 1996-09-26
IL117531A0 (en) 1996-07-23
HUP9801152A2 (en) 1998-08-28
ZA962241B (en) 1997-09-22
ATE196078T1 (en) 2000-09-15
CA2213719C (en) 2005-01-11
MX9706652A (en) 1997-11-29
PT817612E (en) 2001-03-30
EP0817612B1 (en) 2000-09-06
ES2151150T3 (en) 2000-12-16
JPH11502209A (en) 1999-02-23
AU5105396A (en) 1996-10-08
US6063821A (en) 2000-05-16
HUP9801152A3 (en) 2000-06-28
GR3034441T3 (en) 2000-12-29
TW416850B (en) 2001-01-01
DE59605848D1 (en) 2000-10-12
CZ280297A3 (en) 1998-03-18
HU221614B (en) 2002-11-28
KR19980703160A (en) 1998-10-15

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