CA2219909A1 - Processes and compositions for remineralization and prevention of demineralization of dental enamel - Google Patents

Processes and compositions for remineralization and prevention of demineralization of dental enamel

Info

Publication number
CA2219909A1
CA2219909A1 CA002219909A CA2219909A CA2219909A1 CA 2219909 A1 CA2219909 A1 CA 2219909A1 CA 002219909 A CA002219909 A CA 002219909A CA 2219909 A CA2219909 A CA 2219909A CA 2219909 A1 CA2219909 A1 CA 2219909A1
Authority
CA
Canada
Prior art keywords
dental enamel
remineralization
demineralization
water
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002219909A
Other languages
French (fr)
Other versions
CA2219909C (en
Inventor
Norman Usen
Anthony E. Winston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enamelon Inc
Original Assignee
Enamelon, Inc.
Norman Usen
Anthony E. Winston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enamelon, Inc., Norman Usen, Anthony E. Winston filed Critical Enamelon, Inc.
Publication of CA2219909A1 publication Critical patent/CA2219909A1/en
Application granted granted Critical
Publication of CA2219909C publication Critical patent/CA2219909C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A61K8/21—Fluorides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/88—Two- or multipart kits

Abstract

The present invention relates to the problems of remineralization, without demineralization of dental enamel by applying to the teeth a composition which is present in two phases which do not react with one another until introduced into the oral cavity. One phase contains at least one water-soluble calcium compound and the other contains at least one water-soluble inorganic phosphate and at least one water-soluble fluorine compound. In this way the ions which effect remineralization can be absorbed by the dental enamel and their subsequent reaction causes rehardening of demineralized areas in the dental enamel.
CA002219909A 1995-06-06 1996-06-05 Processes and compositions for remineralization and prevention of demineralization of dental enamel Expired - Fee Related CA2219909C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/465,875 1995-06-06
US08/465,875 US5605675A (en) 1995-06-06 1995-06-06 Processes and compositions for remineralization and prevention of demineralization of dental enamel
PCT/US1996/008288 WO1997025967A1 (en) 1995-06-06 1996-06-05 Processes and compositions for remineralization and prevention of demineralization of dental enamel

Publications (2)

Publication Number Publication Date
CA2219909A1 true CA2219909A1 (en) 1997-07-24
CA2219909C CA2219909C (en) 2002-12-03

Family

ID=23849533

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002219909A Expired - Fee Related CA2219909C (en) 1995-06-06 1996-06-05 Processes and compositions for remineralization and prevention of demineralization of dental enamel

Country Status (10)

Country Link
US (2) US5605675A (en)
EP (1) EP0831764B1 (en)
JP (1) JP3786288B2 (en)
KR (1) KR100274334B1 (en)
AU (1) AU700570B2 (en)
BR (1) BR9611259A (en)
CA (1) CA2219909C (en)
DE (1) DE69631960D1 (en)
MX (1) MX9709490A (en)
WO (1) WO1997025967A1 (en)

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Also Published As

Publication number Publication date
AU700570B2 (en) 1999-01-07
BR9611259A (en) 1999-12-28
CA2219909C (en) 2002-12-03
JP2001523217A (en) 2001-11-20
US5605675A (en) 1997-02-25
JP3786288B2 (en) 2006-06-14
EP0831764A1 (en) 1998-04-01
WO1997025967A1 (en) 1997-07-24
US5895641A (en) 1999-04-20
AU7103396A (en) 1997-08-11
EP0831764B1 (en) 2004-03-24
DE69631960D1 (en) 2004-04-29
KR100274334B1 (en) 2000-12-15
EP0831764A4 (en) 2000-09-13
MX9709490A (en) 1998-02-28
KR19990022519A (en) 1999-03-25

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