CA2224164A1 - Intrauterine chemical necrosing method and composition - Google Patents

Intrauterine chemical necrosing method and composition

Info

Publication number
CA2224164A1
CA2224164A1 CA002224164A CA2224164A CA2224164A1 CA 2224164 A1 CA2224164 A1 CA 2224164A1 CA 002224164 A CA002224164 A CA 002224164A CA 2224164 A CA2224164 A CA 2224164A CA 2224164 A1 CA2224164 A1 CA 2224164A1
Authority
CA
Canada
Prior art keywords
composition
tissue
caustic
necrosing
intrauterine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002224164A
Other languages
French (fr)
Other versions
CA2224164C (en
Inventor
Robert S. Neuwirth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2224164A1 publication Critical patent/CA2224164A1/en
Application granted granted Critical
Publication of CA2224164C publication Critical patent/CA2224164C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/38Silver; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

Abstract

A method and composition for effecting chemical necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by delivering a caustic tissue necrosing composition, e.g., a silver nitrate and dextran paste, to the tissue to be necrosed and allowing the paste to remain in contact with the target tissue for a period of time sufficient to chemically necrose substantially the entirety of the tissue lining, and then contacting the caustic composition with a deactivating agent, e.g., an aqueous sodium chloride solution, thereby rendering the caustic composition non-caustic, and then rinsing the cav-ity. Compositions and methods for delivering medicaments are also disclosed.
CA002224164A 1995-06-07 1996-06-06 Intrauterine chemical necrosing method and composition Expired - Fee Related CA2224164C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US48656195A 1995-06-07 1995-06-07
US61478696A 1996-03-08 1996-03-08
US08/486,561 1996-03-08
US08/614,786 1996-03-08
PCT/US1996/009560 WO1996040171A1 (en) 1995-06-07 1996-06-06 Intrauterine chemical necrosing method and composition

Publications (2)

Publication Number Publication Date
CA2224164A1 true CA2224164A1 (en) 1996-12-19
CA2224164C CA2224164C (en) 2007-12-11

Family

ID=27048732

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002224164A Expired - Fee Related CA2224164C (en) 1995-06-07 1996-06-06 Intrauterine chemical necrosing method and composition

Country Status (8)

Country Link
US (1) US6197351B1 (en)
EP (1) EP0831858B1 (en)
JP (1) JP3977422B2 (en)
AT (1) ATE465745T1 (en)
AU (1) AU697897B2 (en)
CA (1) CA2224164C (en)
DE (1) DE69638173D1 (en)
WO (1) WO1996040171A1 (en)

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Also Published As

Publication number Publication date
US6197351B1 (en) 2001-03-06
EP0831858B1 (en) 2010-04-28
AU6162196A (en) 1996-12-30
AU697897B2 (en) 1998-10-22
CA2224164C (en) 2007-12-11
WO1996040171A1 (en) 1996-12-19
JP3977422B2 (en) 2007-09-19
DE69638173D1 (en) 2010-06-10
EP0831858A4 (en) 1999-03-17
MX9709738A (en) 1998-10-31
EP0831858A1 (en) 1998-04-01
ATE465745T1 (en) 2010-05-15
JPH11507353A (en) 1999-06-29

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20130606