CA2226304A1 - Composition pour bio-materiau, procede de preparation - Google Patents

Composition pour bio-materiau, procede de preparation

Info

Publication number
CA2226304A1
CA2226304A1 CA002226304A CA2226304A CA2226304A1 CA 2226304 A1 CA2226304 A1 CA 2226304A1 CA 002226304 A CA002226304 A CA 002226304A CA 2226304 A CA2226304 A CA 2226304A CA 2226304 A1 CA2226304 A1 CA 2226304A1
Authority
CA
Canada
Prior art keywords
pct
biomaterial
composition
sec
date
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002226304A
Other languages
English (en)
Other versions
CA2226304C (fr
Inventor
Guy Daculsi
Pierre Weiss
Anne Dupraz
Mieczyslam Lapkowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National De La Recherche Scientifique (C.N.R.S.)
Guy Daculsi
Pierre Weiss
Anne Dupraz
Mieczyslam Lapkowski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National De La Recherche Scientifique (C.N.R.S.), Guy Daculsi, Pierre Weiss, Anne Dupraz, Mieczyslam Lapkowski filed Critical Centre National De La Recherche Scientifique (C.N.R.S.)
Publication of CA2226304A1 publication Critical patent/CA2226304A1/fr
Application granted granted Critical
Publication of CA2226304C publication Critical patent/CA2226304C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers

Abstract

L'invention a pour objet une composition pour bio-matériau de résorption/substitution de tissus organiques de soutien, comprenant: 20 à 75 % en poids d'une phase minérale constituée par des particules comprenant soit de l'hydroxyapatite (A), éventuellement en mélange avec du phosphate tricalcique .beta. (B), soit du calcium-titane-phosphate (Ca(Ti)4 (PO4)6) (C), et 80 à 25 % en poids d'une phase liquide comprenant une solution aqueuse d'un polymère biocompatible, hydrosoluble, autoréticulable sous l'effet du pH du milieu. Cette composition est stérilisable et injectable. Elle durcit dans les milieux biologiques pour former un bio-matériau de comblement de tissu de soutien.
CA002226304A 1995-08-07 1996-07-29 Composition pour bio-materiau, procede de preparation Expired - Lifetime CA2226304C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9509582A FR2737663B1 (fr) 1995-08-07 1995-08-07 Composition pour bio-materiau, procede de preparation
FR95/09582 1995-08-07
PCT/FR1996/001196 WO1997005911A1 (fr) 1995-08-07 1996-07-29 Composition pour bio-materiau, procede de preparation

Publications (2)

Publication Number Publication Date
CA2226304A1 true CA2226304A1 (fr) 1997-02-20
CA2226304C CA2226304C (fr) 2007-01-09

Family

ID=9481764

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002226304A Expired - Lifetime CA2226304C (fr) 1995-08-07 1996-07-29 Composition pour bio-materiau, procede de preparation

Country Status (14)

Country Link
US (1) US6001394A (fr)
EP (1) EP0843562B1 (fr)
JP (1) JP3597541B2 (fr)
AT (1) ATE214292T1 (fr)
AU (1) AU707039B2 (fr)
CA (1) CA2226304C (fr)
DE (1) DE69619830T2 (fr)
DK (1) DK0843562T3 (fr)
ES (1) ES2173306T3 (fr)
FR (1) FR2737663B1 (fr)
NO (1) NO311604B1 (fr)
PT (1) PT843562E (fr)
WO (1) WO1997005911A1 (fr)
ZA (1) ZA966635B (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417247B1 (en) * 1997-10-14 2002-07-09 Beth L. Armstrong Polymer/ceramic composites
US20020095157A1 (en) 1999-07-23 2002-07-18 Bowman Steven M. Graft fixation device combination
US6179840B1 (en) 1999-07-23 2001-01-30 Ethicon, Inc. Graft fixation device and method
US6599516B1 (en) 2000-09-14 2003-07-29 Etex Corporation Malleable implant containing solid element that resorbs or fractures to provide access channels
US6800245B1 (en) * 2000-11-28 2004-10-05 Vita Special Purpose Corporation Sterile polymerizable systems and kits and methods of their manufacture and use
CA2365376C (fr) * 2000-12-21 2006-03-28 Ethicon, Inc. Utilisation d'implants en mousse renforces ayant une meilleure integrite pour la reparation et la regeneration de tissus mous
US6599323B2 (en) * 2000-12-21 2003-07-29 Ethicon, Inc. Reinforced tissue implants and methods of manufacture and use
US6852330B2 (en) 2000-12-21 2005-02-08 Depuy Mitek, Inc. Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
AU2002331847A1 (en) * 2001-09-14 2003-04-01 Invitrogen Corporation Composition for stabilizing biological materials
WO2003080119A1 (fr) * 2002-03-26 2003-10-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Composites biomedicaux sensibles
JP3806061B2 (ja) * 2002-05-21 2006-08-09 富士通株式会社 金属修飾アパタイト含有膜の形成方法、これに用いられるコーティング液、および金属修飾アパタイト含有膜で被覆された部位を有する電子機器
JP2006501884A (ja) * 2002-08-12 2006-01-19 オステオテック，インコーポレイテッド 骨−ポリマー複合材料の合成
AU2002328444A1 (en) * 2002-09-17 2004-04-08 Fujitsu Limited Photocatalyst apatite-containing film, method of forming the same, coating fluid, and electronic apparatus having member covered with photocatalyst apatite-containing film
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7824701B2 (en) 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
US20050251267A1 (en) * 2004-05-04 2005-11-10 John Winterbottom Cell permeable structural implant
FR2850282B1 (fr) 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
EP1589962B1 (fr) 2003-02-04 2015-04-08 Warsaw Orthopedic, Inc. Polyurethannes pour implants osseux
US7985414B2 (en) * 2003-02-04 2011-07-26 Warsaw Orthopedic, Inc. Polyurethanes for osteoimplants
US8197837B2 (en) 2003-03-07 2012-06-12 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
US10583220B2 (en) 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
EP1529543A1 (fr) * 2003-11-04 2005-05-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Utilisation d'un hydrogel pour la culture de chondrocytes
US7316822B2 (en) 2003-11-26 2008-01-08 Ethicon, Inc. Conformable tissue repair implant capable of injection delivery
US7901461B2 (en) 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
EP1701672A4 (fr) 2003-12-19 2011-04-27 Osteotech Inc Maillage d'origine tissulaire pour la regeneration osseuse
US8012210B2 (en) 2004-01-16 2011-09-06 Warsaw Orthopedic, Inc. Implant frames for use with settable materials and related methods of use
FR2865939B1 (fr) * 2004-02-06 2007-08-31 Biomatlante Utilisation de polymeres organiques silanises pour creation de revetement bioactif, pour implant ou prothese
US11395865B2 (en) 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
US8657881B2 (en) 2004-04-20 2014-02-25 Depuy Mitek, Llc Meniscal repair scaffold
US8137686B2 (en) 2004-04-20 2012-03-20 Depuy Mitek, Inc. Nonwoven tissue scaffold
US8221780B2 (en) 2004-04-20 2012-07-17 Depuy Mitek, Inc. Nonwoven tissue scaffold
US7621963B2 (en) * 2005-04-13 2009-11-24 Ebi, Llc Composite bone graft material
US20060233849A1 (en) * 2005-04-13 2006-10-19 Simon Bruce J Composite bone graft material
DE102005024296B4 (de) * 2005-05-19 2007-02-01 Bundesanstalt für Materialforschung und -Prüfung (BAM) Resorbierbarer, biokompatibler Formkörper und Verfahren zur Herstellung
CA2637616A1 (fr) 2006-01-19 2007-07-26 Osteotech, Inc. Matieres substituts d'os injectables et moulables
AU2007207495A1 (en) 2006-01-19 2007-07-26 Warsaw Orthopedic, Inc. Porous osteoimplant
FR2913199B1 (fr) * 2007-03-01 2009-05-08 Biomatlante Sarl Composition granulaire deshydratee et ses applications biomedicales.
WO2008136733A1 (fr) * 2007-05-04 2008-11-13 Ascendia Ab Procédé et moyens pour cultiver des ostéoblastes
EP2254610A4 (fr) * 2008-02-22 2013-07-31 Dermal Technologies Llc Compositions pour augmentation de tissus
CN102036612B (zh) * 2008-03-28 2014-08-06 骨科技术公司 用于整形外科应用的骨锚
FR2936801A1 (fr) * 2008-10-03 2010-04-09 Centre Nat Rech Scient Procede de silanisation de polysaccharides.
WO2012134540A2 (fr) 2010-10-22 2012-10-04 Vanderbilt University Composite synthétique injectable de polyuréthane (pur)
CA2745038A1 (fr) * 2008-10-30 2010-05-27 Osteotech, Inc. Composites os/polyurethane et procedes associes
CN103242846B (zh) * 2012-02-10 2016-01-13 海洋王照明科技股份有限公司 钛磷酸盐发光薄膜、其制备方法及电致发光器件

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8402534A (nl) * 1984-08-17 1986-03-17 Gerrit Johannes Brinks Materiaal, geschikt voor toepassing als implantatiemateriaal bij mens en dier ter vervanging van afwezig botweefsel, alsmede werkwijze ter bereiding van het materiaal.
JP2877840B2 (ja) * 1989-06-08 1999-04-05 三金工業株式会社 生体硬組織用セメント材料
JP2621622B2 (ja) * 1990-09-27 1997-06-18 三菱マテリアル株式会社 水硬性リン酸カルシウムセメント
DE69214005T2 (de) * 1991-05-01 1997-05-15 Chichibu Onoda Cement Corp Erhärtende Zusammensetzungen zur Verwendung in der Medizin oder Zahnheilkunde
FR2715853B1 (fr) * 1994-02-08 1996-04-26 Centre Nat Rech Scient Composition pour bio-matériau; procédé de préparation.

Also Published As

Publication number Publication date
WO1997005911A1 (fr) 1997-02-20
NO980504D0 (no) 1998-02-05
DE69619830D1 (de) 2002-04-18
JP3597541B2 (ja) 2004-12-08
NO311604B1 (no) 2001-12-17
US6001394A (en) 1999-12-14
ES2173306T3 (es) 2002-10-16
DK0843562T3 (da) 2002-05-21
AU6704296A (en) 1997-03-05
EP0843562B1 (fr) 2002-03-13
NO980504L (no) 1998-04-06
PT843562E (pt) 2002-08-30
CA2226304C (fr) 2007-01-09
EP0843562A1 (fr) 1998-05-27
JPH11510076A (ja) 1999-09-07
ATE214292T1 (de) 2002-03-15
ZA966635B (en) 1998-02-05
FR2737663A1 (fr) 1997-02-14
FR2737663B1 (fr) 1997-10-03
DE69619830T2 (de) 2002-09-12
AU707039B2 (en) 1999-07-01

Similar Documents

Publication Publication Date Title
CA2226304A1 (fr) Composition pour bio-materiau, procede de preparation
AU1711795A (en) Biomaterial composition and method for preparing same
Zhang et al. Calcium phosphate/chitosan composite scaffolds for controlled in vitro antibiotic drug release
LENNOX et al. A histologic comparison of aseptic loosening of cemented, press-fit, and biologic ingrowth prostheses
JP5759370B2 (ja) 組織工学および骨の再生のための、構造化された多孔率を有するモネタイトの三次元マトリクス、および、当該三次元マトリクスの調製方法
Liu et al. Repairing goat tibia segmental bone defect using scaffold cultured with mesenchymal stem cells
DE69733292T2 (de) Verfahren zur in vitro Herstellung von Knochen
AU2456295A (en) A biomaterial and bone implant for bone repair and replacement
ATE355034T1 (de) Implantat zur anwendung im knochen und verfahren zur herstellung eines solchen implantats
Hempel et al. Proliferation and differentiation of osteoblasts on Biocement D modified with collagen type I and citric acid
AU2841099A (en) Method for preparing a biomaterial based on hydroxyapatite, resulting biomaterial and surgical or dental use
ATE224742T1 (de) Verfahren zur herstellung eines implantierbaren verbundwerkstoffs, so hergestellte werkstoffe, und kit zur durchführung des verfahrens
CA2268156A1 (fr) Compositions bioceramiques
CA2362658A1 (fr) Production in vitro de tissus cartilagineux transplantables
CA2265508A1 (fr) Compositions de proteines-16 morphogenetiques osseuses
DE60125164T2 (de) Medizinische implantat-materialien
Sethuraman et al. Novel low temperature setting nanocrystalline calcium phosphate cements for bone repair: Osteoblast cellular response and gene expression studies
Vardaxis et al. Calcification of cross-linked collagen-elastin membrane implants in vivo and their proposed use in bone regeneration
JPH07194373A (ja) 骨髄細胞の培養方法、培養用混合物および硬組織欠損部への移植用材料
SK329592A3 (en) Method of preparation of bioactive material
Rogel Effects of hydroxyapatite crystal morphology on osteoblast-like cell response
CA2246747A1 (fr) Procede favorisant la croissance osseuse a l'aide d'acide hyaluronique et de facteurs de croissance
Simon Jr et al. poly (lactide-co-glycolide) microspheres
El Deeb Discussion: Chemical, Physical, and Histologic Studies on Four Commercial Apatites Used for Alveolar Ridge Augmentation

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20160729