CA2236572A1 - Low temperature calcium phosphate apatite and a method of its manufacture - Google Patents

Low temperature calcium phosphate apatite and a method of its manufacture

Info

Publication number
CA2236572A1
CA2236572A1 CA002236572A CA2236572A CA2236572A1 CA 2236572 A1 CA2236572 A1 CA 2236572A1 CA 002236572 A CA002236572 A CA 002236572A CA 2236572 A CA2236572 A CA 2236572A CA 2236572 A1 CA2236572 A1 CA 2236572A1
Authority
CA
Canada
Prior art keywords
calcium phosphate
phosphate apatite
manufacture
low temperature
apatite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002236572A
Other languages
French (fr)
Other versions
CA2236572C (en
Inventor
Dosuk D. Lee
Christian Rey
Maria Aiolova
Ali Tofighi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Etex Corp
Original Assignee
Etex Corporation
Dosuk D. Lee
Christian Rey
Maria Aiolova
Ali Tofighi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Etex Corporation, Dosuk D. Lee, Christian Rey, Maria Aiolova, Ali Tofighi filed Critical Etex Corporation
Publication of CA2236572A1 publication Critical patent/CA2236572A1/en
Application granted granted Critical
Publication of CA2236572C publication Critical patent/CA2236572C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/325—Preparation by double decomposition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y10S977/775—Nanosized powder or flake, e.g. nanosized catalyst
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/926—Topical chemical, e.g. cosmetic or sunscreen

Abstract

In a method of preparing a low crystallinity calcium phosphate apatite, a low crystallinity calcium phosphate is precipitated from an aqueous solution comprising calcium and phosphate ions; collected from the solution; and dehydrated in a selected humidity and at a selected temperature or lyophilized to minimize growth and promote conversion to calcium phosphate apatite. The resultant calcium phosphate apatite is respectively, a block solid of increased strength, porosity and bioresorbability or a powder.
CA002236572A 1995-11-07 1996-11-07 Low temperature calcium phosphate apatite and a method of its manufacture Expired - Fee Related CA2236572C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/554,817 US5783217A (en) 1995-11-07 1995-11-07 Low temperature calcium phosphate apatite and a method of its manufacture
US08/554,817 1995-11-07
PCT/US1996/017871 WO1997017285A1 (en) 1995-11-07 1996-11-07 Low temperature calcium phosphate apatite and a method of its manufacture

Publications (2)

Publication Number Publication Date
CA2236572A1 true CA2236572A1 (en) 1997-05-15
CA2236572C CA2236572C (en) 2008-04-08

Family

ID=24214827

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002236572A Expired - Fee Related CA2236572C (en) 1995-11-07 1996-11-07 Low temperature calcium phosphate apatite and a method of its manufacture

Country Status (8)

Country Link
US (1) US5783217A (en)
EP (1) EP0859737B1 (en)
JP (1) JP4117803B2 (en)
KR (1) KR100489549B1 (en)
AU (1) AU713435B2 (en)
CA (1) CA2236572C (en)
NZ (1) NZ323168A (en)
WO (1) WO1997017285A1 (en)

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Also Published As

Publication number Publication date
JP2000500110A (en) 2000-01-11
EP0859737B1 (en) 2011-08-31
US5783217A (en) 1998-07-21
EP0859737A1 (en) 1998-08-26
CA2236572C (en) 2008-04-08
NZ323168A (en) 1999-11-29
KR100489549B1 (en) 2005-10-31
KR19990067360A (en) 1999-08-16
AU7723596A (en) 1997-05-29
JP4117803B2 (en) 2008-07-16
WO1997017285A1 (en) 1997-05-15
AU713435B2 (en) 1999-12-02

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