CA2265507A1 - Intracorporeal light treatment of blood - Google Patents

Intracorporeal light treatment of blood

Info

Publication number
CA2265507A1
CA2265507A1 CA002265507A CA2265507A CA2265507A1 CA 2265507 A1 CA2265507 A1 CA 2265507A1 CA 002265507 A CA002265507 A CA 002265507A CA 2265507 A CA2265507 A CA 2265507A CA 2265507 A1 CA2265507 A1 CA 2265507A1
Authority
CA
Canada
Prior art keywords
housing
blood
light
patient
coupled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002265507A
Other languages
French (fr)
Other versions
CA2265507C (en
Inventor
James C. Chen
Brent Wiscombe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Light Sciences Corp
Original Assignee
Light Sciences Limited Partnership
James C. Chen
Brent Wiscombe
Light Sciences Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Light Sciences Limited Partnership, James C. Chen, Brent Wiscombe, Light Sciences Corporation filed Critical Light Sciences Limited Partnership
Publication of CA2265507A1 publication Critical patent/CA2265507A1/en
Application granted granted Critical
Publication of CA2265507C publication Critical patent/CA2265507C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body

Abstract

This invention is a method and apparatus for administering intracorporeal photopheresis to blood flowing in a patient's body to destroy an undesirable component in the blood, where the undesirable component has absorbed a photoreactive agent having a characteristic light absorption wave band. The apparatus includes an implantable housing (100) that is adapted to be placed transcutaneously within a patient's body. An inlet (104), and outlet (102) for a fluid path (128) through the housing (100) are provided, and are coupled to a patient's circulator system so that they convey blood into, and out of, the housing (100). Light sources (110) disposed within the housing (100) (or externally disposed and coupled to the housing by optical fibers) emit light having a wave band substantially equal to the absorption wave band of the photoreactive agent. A portion of the fluid path (128) within the housing (100) is optically transparent so that blood is irradiated with light from the light source (110). The fluid path (128) can have one of several different configurations, including serpentine, planar coil, helical coil, and cross tubes coupling inlet and outlet header manifolds. The light source (110) can comprise light emitting diodes (LEDs) or other types of light sources, and may be coupled to the reactor through optical fibers. The power supply (800) for the light source (110) can be intracorporeal or extracorporeal.
CA002265507A 1996-10-03 1997-08-21 Intracorporeal light treatment of blood Expired - Fee Related CA2265507C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/725,578 US5702432A (en) 1996-10-03 1996-10-03 Intracorporeal light treatment of blood
US08/725,578 1996-10-03
PCT/US1997/014781 WO1998014243A1 (en) 1996-10-03 1997-08-21 Intracorporeal light treatment of blood

Publications (2)

Publication Number Publication Date
CA2265507A1 true CA2265507A1 (en) 1998-04-09
CA2265507C CA2265507C (en) 2002-02-05

Family

ID=24915119

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002265507A Expired - Fee Related CA2265507C (en) 1996-10-03 1997-08-21 Intracorporeal light treatment of blood

Country Status (6)

Country Link
US (1) US5702432A (en)
EP (1) EP1009482A4 (en)
JP (1) JP3164827B2 (en)
AU (1) AU725077B2 (en)
CA (1) CA2265507C (en)
WO (1) WO1998014243A1 (en)

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Also Published As

Publication number Publication date
JP3164827B2 (en) 2001-05-14
US5702432A (en) 1997-12-30
EP1009482A1 (en) 2000-06-21
EP1009482A4 (en) 2001-01-17
AU725077B2 (en) 2000-10-05
CA2265507C (en) 2002-02-05
JP2000503579A (en) 2000-03-28
WO1998014243A1 (en) 1998-04-09
AU4082797A (en) 1998-04-24

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