CA2269132A1 - Compositions to control oral microbial oxidation-reduction (eh) levels - Google Patents

Compositions to control oral microbial oxidation-reduction (eh) levels

Info

Publication number
CA2269132A1
CA2269132A1 CA002269132A CA2269132A CA2269132A1 CA 2269132 A1 CA2269132 A1 CA 2269132A1 CA 002269132 A CA002269132 A CA 002269132A CA 2269132 A CA2269132 A CA 2269132A CA 2269132 A1 CA2269132 A1 CA 2269132A1
Authority
CA
Canada
Prior art keywords
reduction
compositions
levels
oral
microbial oxidation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002269132A
Other languages
French (fr)
Other versions
CA2269132C (en
Inventor
Israel Kleinberg
Milroy Codipilly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24959565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2269132(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2269132A1 publication Critical patent/CA2269132A1/en
Application granted granted Critical
Publication of CA2269132C publication Critical patent/CA2269132C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22—Peroxides; Oxygen; Ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/88—Two- or multipart kits

Abstract

The present invention relates to an oral composition containing a zinc compound containing free available zinc ion and at least one stabilized or stable Eh raising compound distributed in an oral vehicle. The present invention further relates to a method of inhibiting the formation of sulfur containing anions and preventing a reduction in the Eh of the oral cavity. A method of reducing oral malodor and gingivitis and periodontitis is also provided by this invention.
CA002269132A 1996-10-23 1997-10-23 Compositions to control oral microbial oxidation-reduction (eh) levels Expired - Lifetime CA2269132C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73635696A 1996-10-23 1996-10-23
US08/736,356 1996-10-23
PCT/US1997/019598 WO1998017195A1 (en) 1996-10-23 1997-10-23 COMPOSITIONS TO CONTROL ORAL MICROBIAL OXIDATION-REDUCTION (Eh) LEVELS

Publications (2)

Publication Number Publication Date
CA2269132A1 true CA2269132A1 (en) 1998-04-30
CA2269132C CA2269132C (en) 2007-09-04

Family

ID=24959565

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002269132A Expired - Lifetime CA2269132C (en) 1996-10-23 1997-10-23 Compositions to control oral microbial oxidation-reduction (eh) levels

Country Status (16)

Country Link
US (3) US6409992B1 (en)
EP (1) EP0957806B1 (en)
KR (1) KR100567673B1 (en)
CN (1) CN1248155B (en)
AT (1) ATE357884T1 (en)
AU (1) AU716958B2 (en)
BR (1) BR9712569A (en)
CA (1) CA2269132C (en)
DE (1) DE69737532T2 (en)
DK (1) DK0957806T3 (en)
ES (1) ES2281911T3 (en)
HK (1) HK1025494A1 (en)
ID (1) ID22161A (en)
NZ (1) NZ335780A (en)
PT (1) PT957806E (en)
WO (1) WO1998017195A1 (en)

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US20070092552A1 (en) * 2003-04-30 2007-04-26 Tim Clarot Chewable lozenge cold remedy composition and method for making same
AU2004235732B2 (en) * 2003-04-30 2008-04-03 Zicam, Llc Oral spray to reduce cold symptoms and duration of same
US20070092583A1 (en) * 2003-04-30 2007-04-26 Tim Clarot Cold remedy composition comprising zinc salts
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US7658959B2 (en) * 2003-06-12 2010-02-09 Cargill, Incorporated Antimicrobial salt solutions for food safety applications
US7090882B2 (en) * 2003-06-12 2006-08-15 Cargill, Incorporated Antimicrobial salt solutions for food safety applications
US7883732B2 (en) * 2003-06-12 2011-02-08 Cargill, Incorporated Antimicrobial salt solutions for cheese processing applications
US20050170013A1 (en) * 2004-02-04 2005-08-04 Douglas Jerry A. Composition for treating a dermatological inflammatory response and method of preparation thereof
US20070183989A1 (en) * 2005-12-21 2007-08-09 Michael Prencipe Oral Compositions Comprising Zinc Citrate and/or Tocopherol Agents
US8486472B2 (en) * 2006-01-18 2013-07-16 Cargill, Incorporated Antimicrobial salt solutions for food safety applications
US8905760B2 (en) * 2008-11-04 2014-12-09 Duane C. Keller Methods and systems for progressively treating and controlling oral periopathogens causing systemic inflammations
US8956161B2 (en) 2008-11-04 2015-02-17 Duane C Keller Article and method for controlling oral-originated systemic disease
US20100233101A1 (en) * 2009-02-13 2010-09-16 Micropure, Inc. Composition and method for the oxidative consumption of salivary biomolecules
US9968803B2 (en) 2009-10-29 2018-05-15 Colgate-Palmolive Company Low water stannous fluoride plus zinc citrate dentifrice with improved stability, rheology, and efficacy
IT1400707B1 (en) 2010-06-25 2013-06-28 Farmaceutici Dott Ciccarelli S P A USE OF ANTIBACTERIAL COMPOUNDS FOR ORAL CABLE HYGIENE
MX2013001493A (en) 2010-08-07 2013-08-27 Univ New York State Res Found Oral compositions comprising a zinc compound and an anti-microbial agent.
US8591229B2 (en) 2010-12-16 2013-11-26 Duane C. Keller Devices and methods for creating a positive pressure environment for treatment of oral biofilms associated with periodontal disease
AU2010365811B2 (en) 2010-12-21 2016-02-11 Colgate-Palmolive Company Metal salt compositions
US20140065078A1 (en) * 2012-08-31 2014-03-06 Dr. Fresh, Llc Oral care composition for promoting and maintaining oral health and method of forming and using same
US9403181B2 (en) * 2013-07-26 2016-08-02 Paul O'Malley Oral care product formulation
WO2018126107A1 (en) * 2016-12-29 2018-07-05 Board Of Regents, The University Of Texas System Methylene blue solution for the treatment of oral lesions
WO2019013750A1 (en) * 2017-07-10 2019-01-17 Gargle Water, Inc. Pharyngeal or buccal cavity rinse and process of use thereof
EP4335481A2 (en) 2017-08-25 2024-03-13 AZ Solutions LLC System and method for wound treatment and irrigation
US11918549B2 (en) 2017-08-25 2024-03-05 AZ Solutions LLC System and method for wound treatment and irrigation
US10960129B2 (en) * 2017-08-25 2021-03-30 AZ Solutions LLC System and method for patient skin treatment and irrigation
CN112272578A (en) * 2018-04-27 2021-01-26 阿勒根公司 Sodium chlorite compositions with enhanced antimicrobial efficacy and reduced toxicity
CA3103914A1 (en) * 2018-06-25 2020-01-02 Triumph Pharmaceuticals Inc. Methods of inhibiting microbial infections using zinc-containing compositions
CA3136627C (en) * 2019-04-10 2024-01-02 Black Tulip Management, Inc. Oral rinse compositions for reducing pathogens underlying and for treating periodontal disease and oral malodor in the canine
EP3952828A4 (en) * 2019-04-10 2023-06-07 Black Tulip Management, Inc. Oral rinse compositions for reducing pathogens underlying tooth decay, periodontitis and oral malodor

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Also Published As

Publication number Publication date
DE69737532T2 (en) 2008-04-10
BR9712569A (en) 1999-12-21
DE69737532D1 (en) 2007-05-10
ATE357884T1 (en) 2007-04-15
HK1025494A1 (en) 2000-11-17
JP2001503402A (en) 2001-03-13
JP5041617B2 (en) 2012-10-03
ES2281911T3 (en) 2007-10-01
CN1248155A (en) 2000-03-22
CA2269132C (en) 2007-09-04
KR100567673B1 (en) 2006-04-05
AU716958B2 (en) 2000-03-09
US20020182267A1 (en) 2002-12-05
CN1248155B (en) 2010-04-21
US6409992B1 (en) 2002-06-25
WO1998017195A1 (en) 1998-04-30
EP0957806A4 (en) 2003-06-11
US6423300B1 (en) 2002-07-23
PT957806E (en) 2007-05-31
NZ335780A (en) 2001-01-26
DK0957806T3 (en) 2007-07-30
US6929790B2 (en) 2005-08-16
EP0957806A1 (en) 1999-11-24
KR20000052783A (en) 2000-08-25
AU5093998A (en) 1998-05-15
EP0957806B1 (en) 2007-03-28
ID22161A (en) 1999-09-09

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Legal Events

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EEER Examination request
MKEX Expiry

Effective date: 20171023

MKEX Expiry

Effective date: 20171023

MKEX Expiry

Effective date: 20171023