CA2281473A1 - Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same - Google Patents

Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same Download PDF

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Publication number
CA2281473A1
CA2281473A1 CA002281473A CA2281473A CA2281473A1 CA 2281473 A1 CA2281473 A1 CA 2281473A1 CA 002281473 A CA002281473 A CA 002281473A CA 2281473 A CA2281473 A CA 2281473A CA 2281473 A1 CA2281473 A1 CA 2281473A1
Authority
CA
Canada
Prior art keywords
methods
dosage form
manufacture
same
form exhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002281473A
Other languages
French (fr)
Other versions
CA2281473C (en
Inventor
Jaedeok Yoo
Sandeep Kumar
Donald C. Monkhouse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2281473A1 publication Critical patent/CA2281473A1/en
Application granted granted Critical
Publication of CA2281473C publication Critical patent/CA2281473C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing

Abstract

A rapidly dispersing dosage form is described, which releases its active ingredients within a period of less than about ninety seconds.
These dosage forms exhibit a three-dimensional shape that is retained for adequate storage but is readily dispersed in the presence of excess moisture. Also disclosed are methods of administration of a medicament and a process for the preparation of rapidly dispersing dosage forms.
CA002281473A 1997-02-20 1998-02-20 Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same Expired - Lifetime CA2281473C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3828497P 1997-02-20 1997-02-20
US3888397P 1997-02-20 1997-02-20
US60/038,883 1997-02-20
US60/038,284 1997-02-20
PCT/US1998/003256 WO1998036738A1 (en) 1997-02-20 1998-02-20 Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same

Publications (2)

Publication Number Publication Date
CA2281473A1 true CA2281473A1 (en) 1998-08-27
CA2281473C CA2281473C (en) 2007-01-16

Family

ID=26715043

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002281473A Expired - Lifetime CA2281473C (en) 1997-02-20 1998-02-20 Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same

Country Status (9)

Country Link
US (3) US6471992B1 (en)
EP (1) EP0973507B1 (en)
JP (3) JP4563516B2 (en)
AT (1) ATE421318T1 (en)
AU (1) AU736912B2 (en)
CA (1) CA2281473C (en)
DE (1) DE69840495D1 (en)
ES (1) ES2318869T3 (en)
WO (1) WO1998036738A1 (en)

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Also Published As

Publication number Publication date
JP2001512488A (en) 2001-08-21
EP0973507A1 (en) 2000-01-26
JP2010120938A (en) 2010-06-03
AU6331498A (en) 1998-09-09
US20030133975A1 (en) 2003-07-17
US9463160B2 (en) 2016-10-11
WO1998036738A1 (en) 1998-08-27
EP0973507A4 (en) 2006-08-23
DE69840495D1 (en) 2009-03-12
AU736912B2 (en) 2001-08-02
ES2318869T3 (en) 2009-05-01
JP5091910B2 (en) 2012-12-05
JP4563516B2 (en) 2010-10-13
CA2281473C (en) 2007-01-16
JP2009215305A (en) 2009-09-24
ATE421318T1 (en) 2009-02-15
EP0973507B1 (en) 2009-01-21
US6471992B1 (en) 2002-10-29
US9114072B2 (en) 2015-08-25
US20120207929A1 (en) 2012-08-16

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Effective date: 20180220