CA2281649A1 - System and method for separation of particles - Google Patents

System and method for separation of particles Download PDF

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Publication number
CA2281649A1
CA2281649A1 CA002281649A CA2281649A CA2281649A1 CA 2281649 A1 CA2281649 A1 CA 2281649A1 CA 002281649 A CA002281649 A CA 002281649A CA 2281649 A CA2281649 A CA 2281649A CA 2281649 A1 CA2281649 A1 CA 2281649A1
Authority
CA
Canada
Prior art keywords
particles
fluid chamber
separating
liquid
liquids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002281649A
Other languages
French (fr)
Other versions
CA2281649C (en
Inventor
Todd Curtis Green
Raymond P. Goodrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo BCT Inc
Original Assignee
Cobe Laboratories, Inc.
Todd Curtis Green
Raymond P. Goodrich
Gambro, Inc.
Gambro Bct, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cobe Laboratories, Inc., Todd Curtis Green, Raymond P. Goodrich, Gambro, Inc., Gambro Bct, Inc. filed Critical Cobe Laboratories, Inc.
Priority to CA002552444A priority Critical patent/CA2552444A1/en
Publication of CA2281649A1 publication Critical patent/CA2281649A1/en
Application granted granted Critical
Publication of CA2281649C publication Critical patent/CA2281649C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A61M1/0227—Multiple bag systems for separating or storing blood components with filters and means for securing the filter against damage, e.g. during centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0471—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with additional elutriation separation of different particles

Abstract

A system and method are disclosed for separating particles having different sedimentation velocities. The system includes a fluid chamber for separating the parti-cles from one another. Conduits are provided for flow-ing liquid carrying particles to the fluid chamber and for mixing the liquid with a diluting liquid. Structure is also provided for separating particles from the liquids after the particles are separated in the fluid chamber.
The disclosed methods include forming a saturated flu-idized bed of first particles to retain second particles in the fluid chamber. A diluting liquid having a density less than that of the particles is mixed with the liq-uid carrying particles to reduce overall density of sub-stances in the fluid chamber and thereby reduce Coriolis jetting of liquids in the fluid chamber.
CA002281649A 1998-01-20 1999-01-19 System and method for separation of particles Expired - Fee Related CA2281649C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002552444A CA2552444A1 (en) 1998-01-20 1999-01-19 System and method for separation of particles

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/009,378 1998-01-20
US09/009,378 US6051146A (en) 1998-01-20 1998-01-20 Methods for separation of particles
PCT/US1999/000353 WO1999036111A1 (en) 1998-01-20 1999-01-19 System and method for separation of particles

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002552444A Division CA2552444A1 (en) 1998-01-20 1999-01-19 System and method for separation of particles

Publications (2)

Publication Number Publication Date
CA2281649A1 true CA2281649A1 (en) 1999-07-22
CA2281649C CA2281649C (en) 2007-07-03

Family

ID=21737297

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002281649A Expired - Fee Related CA2281649C (en) 1998-01-20 1999-01-19 System and method for separation of particles

Country Status (7)

Country Link
US (1) US6051146A (en)
EP (2) EP0973564B1 (en)
JP (1) JP3299284B2 (en)
CA (1) CA2281649C (en)
DE (2) DE69931085T2 (en)
ES (1) ES2243043T3 (en)
WO (1) WO1999036111A1 (en)

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Also Published As

Publication number Publication date
CA2281649C (en) 2007-07-03
DE69931085T2 (en) 2007-04-26
ES2243043T3 (en) 2005-11-16
DE69926313D1 (en) 2005-09-01
US6051146A (en) 2000-04-18
JP3299284B2 (en) 2002-07-08
EP1493459B1 (en) 2006-04-26
EP0973564B1 (en) 2005-07-27
JP2000514103A (en) 2000-10-24
EP0973564A1 (en) 2000-01-26
DE69931085D1 (en) 2006-06-01
WO1999036111A1 (en) 1999-07-22
EP1493459A1 (en) 2005-01-05
DE69926313T2 (en) 2006-04-20

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