CA2281773A1 - Multiautoclave for combinatorial synthesis of zeolites and other materials - Google Patents

Multiautoclave for combinatorial synthesis of zeolites and other materials Download PDF

Info

Publication number
CA2281773A1
CA2281773A1 CA002281773A CA2281773A CA2281773A1 CA 2281773 A1 CA2281773 A1 CA 2281773A1 CA 002281773 A CA002281773 A CA 002281773A CA 2281773 A CA2281773 A CA 2281773A CA 2281773 A1 CA2281773 A1 CA 2281773A1
Authority
CA
Canada
Prior art keywords
multiautoclave
perforations
zeolites
synthesis
chambers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002281773A
Other languages
French (fr)
Other versions
CA2281773C (en
Inventor
Ivar Martin Dahl
Arne Karlsson
Rune Wendelbo
Duncan E. Akporiaye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sinvent AS
Original Assignee
Ivar Martin Dahl
Arne Karlsson
Rune Wendelbo
Duncan E. Akporiaye
Sinvent As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19900405&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2281773(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ivar Martin Dahl, Arne Karlsson, Rune Wendelbo, Duncan E. Akporiaye, Sinvent As filed Critical Ivar Martin Dahl
Publication of CA2281773A1 publication Critical patent/CA2281773A1/en
Application granted granted Critical
Publication of CA2281773C publication Critical patent/CA2281773C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
    • B01J3/04—Pressure vessels, e.g. autoclaves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B39/00—Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites; Their preparation; After-treatment, e.g. ion-exchange or dealumination
    • C01B39/02—Crystalline aluminosilicate zeolites; Isomorphous compounds thereof; Direct preparation thereof; Preparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactants; After-treatment thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00319—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks the blocks being mounted in stacked arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00331—Details of the reactor vessels
    • B01J2219/00333—Closures attached to the reactor vessels
    • B01J2219/00335—Septa
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00331—Details of the reactor vessels
    • B01J2219/00333—Closures attached to the reactor vessels
    • B01J2219/00349—Spheres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00477—Means for pressurising the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00601—High-pressure processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/00745—Inorganic compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/00745—Inorganic compounds
    • B01J2219/00747—Catalysts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/00745—Inorganic compounds
    • B01J2219/0075—Metal based compounds
    • B01J2219/00754—Metal oxides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/08—Methods of screening libraries by measuring catalytic activity
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/18—Libraries containing only inorganic compounds or inorganic materials
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Abstract

The invention relates to a multiautoclave and details of its design and a method for automated synthesis of zeolites in said multiautoclave and, furthermore, application of the multiautoclave for an automated synthesis which is optimized simultaneously with regard to several synthesis parameters in the synthesis of zeolites. The multiautoclave consists typically of a pressure vessel/autoclave lined with an inert material with from 10 to 10.000 small, separated chambers, each typically having a volume of 0,2-2 ml, the chambers preferably being formed as through-going perforations in a central block and the perforations are sealed by means of balls, septa, stoppers or such which are placed at the bottom and top of each through-going perforation, and metal plates are placed over and under the Teflon plate so that the closing mechanism is pressed against the edges of the perforations in the Teflon plate with sufficient load to enable the chambers to be filled with aqueous mixtures and to be heated to 200 ~C without the occurence of leakage.
Top-and bottom plates and closing mechanisms can be integrated so that all the perforations are sealed simultaneously when these are placed at the top and bottom sides of the central block.
CA002281773A 1997-02-20 1998-02-20 Multiautoclave for combinatorial synthesis of zeolites and other materials Expired - Fee Related CA2281773C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO970788A NO304355B1 (en) 1997-02-20 1997-02-20 Multi-autoclave for methodical, automated synthesis of zeolites and other compounds
NO970788 1997-02-20
PCT/NO1998/000051 WO1998036826A1 (en) 1997-02-20 1998-02-20 Multiautoclave for combinatorial synthesis of zeolites and other materials

Publications (2)

Publication Number Publication Date
CA2281773A1 true CA2281773A1 (en) 1998-08-27
CA2281773C CA2281773C (en) 2003-06-17

Family

ID=19900405

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002281773A Expired - Fee Related CA2281773C (en) 1997-02-20 1998-02-20 Multiautoclave for combinatorial synthesis of zeolites and other materials

Country Status (11)

Country Link
US (1) US6821486B1 (en)
EP (1) EP0968050B1 (en)
JP (1) JP3372553B2 (en)
AT (1) ATE206068T1 (en)
AU (1) AU6231798A (en)
CA (1) CA2281773C (en)
DE (1) DE69801813T2 (en)
DK (1) DK0968050T3 (en)
ES (1) ES2166143T3 (en)
NO (1) NO304355B1 (en)
WO (1) WO1998036826A1 (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7014049B2 (en) * 1996-12-23 2006-03-21 Glycorex Transplantation Ab Device for bio-affinity material
US6893877B2 (en) 1998-01-12 2005-05-17 Massachusetts Institute Of Technology Methods for screening substances in a microwell array
DE19822077A1 (en) * 1998-05-16 1999-11-18 Studiengesellschaft Kohle Mbh Preparation of library of spatially separted solids by wet-chemical methods on a removable reaction plate, used e.g. to screen for new catalysts or materials
US7115231B1 (en) 1998-06-09 2006-10-03 Symyx Technologies, Inc. Parallel reactor with knife-edge seal
US6410332B1 (en) * 1998-09-08 2002-06-25 Symyx Technologies, Inc. Sampling and analysis of reactions by trapping reaction components on a sorbent
US6485692B1 (en) 1998-12-04 2002-11-26 Symyx Technologies, Inc. Continuous feed parallel reactor
AU2368900A (en) 1998-12-18 2000-07-03 Symyx Technologies, Inc. Apparatus and method for characterizing libraries of different materials using x-ray scattering
AU756982B2 (en) 1999-03-19 2003-01-30 Life Technologies Corporation Multi-through hole testing plate for high throughput screening
NO312921B1 (en) * 1999-07-05 2002-07-15 Sinvent As Multitest compilation for evaluation, detection and monitoring of processes at elevated pressure
US6770245B2 (en) 1999-12-15 2004-08-03 Uop Llc Multiple parallel processing assembly
US6776963B1 (en) 1999-12-15 2004-08-17 Uop Llc Multiple parallel catalytic reactor assembly
US6627445B1 (en) 1999-12-15 2003-09-30 Uop Llc Process for simultaneously evaluating a plurality of catalysts
US6342185B1 (en) 1999-12-15 2002-01-29 Uop Llc Combinatorial catalytic reactor
US6576196B1 (en) 1999-12-15 2003-06-10 Uop Llc Multiple parallel catalytic reactor assembly
US6368865B1 (en) 1999-12-15 2002-04-09 Uop Llc Combinatorial process for performing catalytic chemical reactions
US20020151040A1 (en) 2000-02-18 2002-10-17 Matthew O' Keefe Apparatus and methods for parallel processing of microvolume liquid reactions
DE10031587A1 (en) * 2000-06-29 2002-01-10 Basf Ag Dosing of microscale suspensions for the production of material samples in combinatorial materials research and their testing
WO2002007873A2 (en) * 2000-07-19 2002-01-31 Uop Llc Multiautoclave with liner for combinatorial synthesis of zeolites and other materials
US7018589B1 (en) 2000-07-19 2006-03-28 Symyx Technologies, Inc. High pressure parallel reactor
DE10049078A1 (en) * 2000-10-02 2002-04-18 Aventis Res & Tech Gmbh & Co Apparatus for investigating chemical reactions used in chemical synthesis and biotechnology, comprises a graduated autoclave array of autoclave modules consisting of a reactor casing fixed via a reaction vessel
US20020160527A1 (en) 2001-02-26 2002-10-31 3M Innovative Properties Company Combinatorial library comprising pouches as packages for library members and method therefor
US7514263B2 (en) 2001-04-02 2009-04-07 3M Innovative Properties Company Continuous process for the production of combinatorial libraries of materials
US6808685B2 (en) 2001-09-17 2004-10-26 Uop Llc Apparatus and method for generating a plurality of isolated effluents
US20030173205A1 (en) 2002-03-12 2003-09-18 Arne Karlsson Process vessel with integral evaporator
US7063982B1 (en) 2002-03-12 2006-06-20 Uop Llc Process of vaporizing and reacting a liquid feed
US6989131B2 (en) 2002-03-12 2006-01-24 Uop Llc Catalytic reactor with integral evaporator
US7122159B2 (en) 2002-04-29 2006-10-17 Symyx Technologies, Inc. High pressure parallel reactor with individually sealable vessels
US8277753B2 (en) 2002-08-23 2012-10-02 Life Technologies Corporation Microfluidic transfer pin
US7141217B2 (en) 2002-12-05 2006-11-28 Uop Llc Elevated pressure apparatus and method for generating a plurality of isolated effluents
WO2004074818A2 (en) 2002-12-20 2004-09-02 Biotrove, Inc. Assay apparatus and method using microfluidic arrays
US7578993B2 (en) * 2003-10-31 2009-08-25 Uop Llc Process for preparing crystalline aluminosilicate compositions using charge density matching
CA2559171A1 (en) 2004-03-12 2005-09-29 Biotrove, Inc. Nanoliter array loading
US7341872B1 (en) * 2004-04-29 2008-03-11 Uop Llc Multiautoclave with set of vessels for combinatorial synthesis of zeolites and other materials
US7655191B2 (en) 2007-05-14 2010-02-02 Symyx Solutions, Inc. Methods for chemical reactions in a parallel batch reactor
US7807109B2 (en) 2007-05-14 2010-10-05 Freeslate, Inc. Parallel batch reactor with pressure monitoring
DE102007047658A1 (en) * 2007-10-05 2009-04-09 Hte Ag The High Throughput Experimentation Company Parallel reactor with pressure lock
MX2010005882A (en) * 2008-01-15 2010-12-02 Uop Llc Multiautoclave with set of vessels for combinatorial synthesis of zeolites and other materials.
JP2013240758A (en) * 2012-05-21 2013-12-05 Tokyo Univ Of Science Reaction apparatus for performing combinatorial synthesis, combinatorial synthesis system, and combinatorial synthesis method
FR3063995A1 (en) * 2017-03-17 2018-09-21 Arkema France PROCESS FOR MULTI-REACTOR SYNTHESIS OF ZEOLITHE CRYSTALS WITH CONTROLLED GRANULOMETRY

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2835003A (en) * 1955-04-14 1958-05-20 Victor R Abrams Method and apparatus for sterilizing containers
US3130007A (en) 1961-05-12 1964-04-21 Union Carbide Corp Crystalline zeolite y
US3147068A (en) * 1962-03-01 1964-09-01 Wilmot Castle Co Closure apparatus for pressure chamber
FR2041474A5 (en) * 1969-04-25 1971-01-29 Beauvais Max
US3681008A (en) * 1970-12-14 1972-08-01 Robert B Black Autoclave
US4099923A (en) 1977-01-17 1978-07-11 The Standard Oil Company Automatic catalytic screening unit
US4583643A (en) * 1983-04-08 1986-04-22 Sanderson Roger S Sterile bag
US4493815A (en) * 1983-07-28 1985-01-15 Bio-Rad Laboratories, Inc. Supporting and filtering biochemical test plate assembly
DE3565986D1 (en) 1984-05-02 1988-12-08 Brendan James Hamill An apparatus for the chemical synthesis of oligonucleotides
US4948442A (en) * 1985-06-18 1990-08-14 Polyfiltronics, Inc. Method of making a multiwell test plate
DE3617153A1 (en) * 1986-05-22 1987-11-26 Wagner Gmbh VALVE FOR STERILIZING CONTAINER
US5312506A (en) 1987-06-15 1994-05-17 Mitsui Mining Company, Limited Method for growing single crystals from melt
US5277876A (en) * 1987-08-28 1994-01-11 Wagner Gmbh Fabrik Fur Medizinische Valve apparatus and method for sterilizer container
US5096676A (en) * 1989-01-27 1992-03-17 Mcpherson Alexander Crystal growing apparatus
US5056427A (en) 1989-03-15 1991-10-15 Seiko Instruments Inc. Sealing of cavity on reagent tray
IT1237142B (en) 1989-11-28 1993-05-24 AUTOCLAVE TO CREATE STRONG REDUCTIONS IN THE QUANTITIES OF PROCESS FLUIDS USED AND ECONOMIES ON ENERGY CONSUMPTION
US5039493A (en) 1990-05-04 1991-08-13 The United States Of America As Represented By The Secretary Of The Navy Positive pressure blotting apparatus with hydropholic filter means
US5013531A (en) 1990-08-31 1991-05-07 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Macromolecular crystal growing system
JP2740375B2 (en) 1990-10-25 1998-04-15 富士通株式会社 Biopolymer crystallization equipment
US5282543A (en) 1990-11-29 1994-02-01 The Perkin Elmer Corporation Cover for array of reaction tubes
WO1992010284A2 (en) 1990-12-07 1992-06-25 Cnc Development, Inc. Catalytic chemical reactor
US5322591A (en) 1991-03-26 1994-06-21 The United States Of America As Represented By The Secretary Of The Air Force Hydrothermal growth on non-linear optical crystals
US5112574A (en) * 1991-04-26 1992-05-12 Imanigation, Ltd. Multititer stopper array for multititer plate or tray
EP0607262A1 (en) 1991-10-09 1994-07-27 Schering Corporation Crystal forming device and automated crystallization system
US5319436A (en) 1992-05-28 1994-06-07 Packard Instrument Company, Inc. Microplate farming wells with transparent bottom walls for assays using light measurements
US5505916A (en) 1992-08-25 1996-04-09 C/T Med--Systems Ltd. Inc. Autoclave cassette
US5324483B1 (en) 1992-10-08 1996-09-24 Warner Lambert Co Apparatus for multiple simultaneous synthesis
FR2700010B1 (en) 1992-12-24 1995-03-17 Rocher Yves Biolog Vegetale Method and device for testing the reactivity of cells with regard to products.
US6258325B1 (en) * 1993-04-19 2001-07-10 Ashok Ramesh Sanadi Method and apparatus for preventing cross-contamination of multi-well test plates
US5342581A (en) 1993-04-19 1994-08-30 Sanadi Ashok R Apparatus for preventing cross-contamination of multi-well test plates
US5400741A (en) * 1993-05-21 1995-03-28 Medical Foundation Of Buffalo, Inc. Device for growing crystals
US5961926A (en) 1993-09-27 1999-10-05 Packard Instrument Co., Inc. Microplate assembly and method of preparing samples for analysis in a microplate assembly
BR9407947A (en) 1993-11-02 1996-11-26 Affymax Tech Nv Process for synthesizing diverse molecules on a plurality of substrates and a labeled molecular collection to perform copulation reactions on beads in parallel to screen a labeled molecular collection to detect the presence of one or more different labels and to determine the sequence of synthesis apparatus for reactions parallel copulation devices on solid supports optical alignment block for use with an optical detector delivery systems for dispensing device reagents
US5476107A (en) * 1993-11-16 1995-12-19 Tetrad Corporation Method and apparatus for disinfecting electronic surgical probes
JPH07185313A (en) * 1993-12-28 1995-07-25 Fujitsu Ltd Manufacturing device used in environment of micro gravity
DE59408037D1 (en) * 1994-01-18 1999-05-06 Sci Can Arrangement for steam sterilization of medical instruments, implants and the like
US5580523A (en) 1994-04-01 1996-12-03 Bard; Allen J. Integrated chemical synthesizers
EP0691132B1 (en) * 1994-07-05 2001-11-28 Excalibur Medical (Proprietary) Limited Autoclave
US5985356A (en) 1994-10-18 1999-11-16 The Regents Of The University Of California Combinatorial synthesis of novel materials
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5641681A (en) * 1995-04-17 1997-06-24 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Device and method for screening crystallization conditions in solution crystal growth
US5609837A (en) * 1995-08-16 1997-03-11 Cerny; David E. Disinfection apparatus
US5716584A (en) 1995-09-07 1998-02-10 Pathogenesis Corporation Device for the synthesis of compounds in an array
DE19548742C1 (en) * 1995-12-23 1997-05-28 Dornier Gmbh Apparatus for growing zeolite crystals from an aqueous solution
US5753187A (en) * 1996-06-14 1998-05-19 Stovall Life Science, Inc. Combinatorial chemistry cassette
DE19632779A1 (en) 1996-08-15 1998-02-19 Hoechst Ag Method and device for investigating chemical reactions in miniaturized reactors connected in parallel
US6010670A (en) * 1998-06-03 2000-01-04 Berry, Jr.; Bernie B. Sterilization assembly for instrument case

Also Published As

Publication number Publication date
CA2281773C (en) 2003-06-17
DE69801813T2 (en) 2002-05-16
JP2001500429A (en) 2001-01-16
ES2166143T3 (en) 2002-04-01
EP0968050A1 (en) 2000-01-05
NO304355B1 (en) 1998-12-07
DK0968050T3 (en) 2002-01-07
WO1998036826A1 (en) 1998-08-27
DE69801813D1 (en) 2001-10-31
NO970788D0 (en) 1997-02-20
AU6231798A (en) 1998-09-09
US6821486B1 (en) 2004-11-23
NO970788L (en) 1998-08-21
ATE206068T1 (en) 2001-10-15
JP3372553B2 (en) 2003-02-04
EP0968050B1 (en) 2001-09-26

Similar Documents

Publication Publication Date Title
CA2281773A1 (en) Multiautoclave for combinatorial synthesis of zeolites and other materials
CA2107543A1 (en) Perforated Plate Fluid Distributor and Its Associated Fixed Bed Vessel
CA2420172A1 (en) Flexible container having flat walls
CA2452584A1 (en) Self-absorbing gas-barrier receptacle for food packaging and food package obtained therefrom
DE20110108U1 (en) Containers with separate receiving rooms
CA2445852A1 (en) Packaging system for coffee
DE60307325T2 (en) FOOD PACKAGING AND METHOD FOR HEATING A FOOD PACKAGING
EP0281537A3 (en) A method for transport of one-unit packed products which give off moisture and need cooling, and packings for use in carrying out said method
ZA899354B (en) A single handle lid opening,closing and locking mechanism for a large capacity pressure cooker
CA2093820A1 (en) Infusion package
DE1486095A1 (en) Device for filling containers
US6166391A (en) Uranium oxide shipping container
WO2002007873A3 (en) Multiautoclave with liner for combinatorial synthesis of zeolites and other materials
MY113919A (en) Layered tablet for the controlled release of active substances
AU2453101A (en) Micro-titer plate and method of making same
DE3866438D1 (en) DEGASSING LOCK FOR LIQUID CONTAINERS.
EP0850175A1 (en) Package and storage device for storing separately effervescent tablets and effervescent powders resp. granules and their solvent materials
JP2005059954A (en) Packaging container for fermented food
CN219000130U (en) A unloading box subassembly and unloader for among intelligent cooking machine
WO2003047756A3 (en) Device and method for processing biological or chemical substances or substance mixtures thereof
FR2660287B1 (en) CONTAINER FOR PRODUCT TO BE HEATED OR BAKED IN AN OVEN SUCH AS A MICROWAVE OVEN, CLOSED BY A LID FIXED BY THERMOSCELLING.
JPS57107812A (en) Method for packing
JPS6470349A (en) Double container for food and preparation thereof
EP1241420A2 (en) Valve arrangement for self-cooling beverage containers
CA2148069A1 (en) Reactor and use thereof

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed