CA2289756A1 - Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties - Google Patents

Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties Download PDF

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Publication number
CA2289756A1
CA2289756A1 CA002289756A CA2289756A CA2289756A1 CA 2289756 A1 CA2289756 A1 CA 2289756A1 CA 002289756 A CA002289756 A CA 002289756A CA 2289756 A CA2289756 A CA 2289756A CA 2289756 A1 CA2289756 A1 CA 2289756A1
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CA
Canada
Prior art keywords
hydrogel composites
cross
mechanical strength
superporous
disintegrant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002289756A
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French (fr)
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CA2289756C (en
Inventor
Kinam Park
Jun Chen
Haesun Park
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Purdue Research Foundation
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Purdue Research Foundation
Kinam Park
Jun Chen
Haesun Park
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Application filed by Purdue Research Foundation, Kinam Park, Jun Chen, Haesun Park filed Critical Purdue Research Foundation
Publication of CA2289756A1 publication Critical patent/CA2289756A1/en
Application granted granted Critical
Publication of CA2289756C publication Critical patent/CA2289756C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/60Liquid-swellable gel-forming materials, e.g. super-absorbents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F251/00Macromolecular compounds obtained by polymerising monomers on to polysaccharides or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00

Abstract

A superporous hydrogel composite is formed by polymerizing one or more ethylenically-unsaturated monomers, and a multiolefinic cross-linking agent, in the presence of particles of a disintegrant and a blowing agent. The disintegrant, which rapidly absorbs water, serves to greatly increase the mechanical strength of the superporous hydrogel and significantly shortens the time required to absorb water and swell. Superporous hydrogel composites prepared by this method have an average pore size in the range of 10 µm to 3,000 µm. Preferred particles of disintegrant include natural and synthetic charged polymers, such as cross-linked sodium carboxymethylcellulose, cross-linked sodium starch glycolate, and cross-linked polyvinylpyrrolidone. The blowing agent is preferably a compound that releases gas bubbles upon acidification, such as NaHCO3. Improved hydrogel composites formed without a blowing agent are also provided.
CA002289756A 1997-05-13 1998-05-08 Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties Expired - Fee Related CA2289756C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/855,499 US6271278B1 (en) 1997-05-13 1997-05-13 Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
US08/855,499 1997-05-13
PCT/IB1998/000686 WO1998051408A1 (en) 1997-05-13 1998-05-08 Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strenght, and superabsorbent properties

Publications (2)

Publication Number Publication Date
CA2289756A1 true CA2289756A1 (en) 1998-11-19
CA2289756C CA2289756C (en) 2008-03-11

Family

ID=25321410

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002289756A Expired - Fee Related CA2289756C (en) 1997-05-13 1998-05-08 Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties

Country Status (10)

Country Link
US (2) US6271278B1 (en)
EP (1) EP0988108B1 (en)
JP (1) JP2002501563A (en)
CN (1) CN1264321A (en)
AT (1) ATE300999T1 (en)
AU (1) AU736940B2 (en)
BR (1) BR9809815A (en)
CA (1) CA2289756C (en)
DE (1) DE69831074T2 (en)
WO (1) WO1998051408A1 (en)

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