CA2315192A1 - Method and device for tissue modulation - Google Patents

Method and device for tissue modulation Download PDF

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Publication number
CA2315192A1
CA2315192A1 CA002315192A CA2315192A CA2315192A1 CA 2315192 A1 CA2315192 A1 CA 2315192A1 CA 002315192 A CA002315192 A CA 002315192A CA 2315192 A CA2315192 A CA 2315192A CA 2315192 A1 CA2315192 A1 CA 2315192A1
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CA
Canada
Prior art keywords
tissue
blood
region
replete
apposition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002315192A
Other languages
French (fr)
Other versions
CA2315192C (en
Inventor
Joseph Chaiken
Charles M. Peterson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LighTouch Medical Inc
Original Assignee
Lightouch Medical, Inc.
Joseph Chaiken
Charles M. Peterson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lightouch Medical, Inc., Joseph Chaiken, Charles M. Peterson filed Critical Lightouch Medical, Inc.
Publication of CA2315192A1 publication Critical patent/CA2315192A1/en
Application granted granted Critical
Publication of CA2315192C publication Critical patent/CA2315192C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552—Details of sensors specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
    • A61B5/0053—Detecting, measuring or recording by applying mechanical forces or stimuli by applying pressure, e.g. compression, indentation, palpation, grasping, gauging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • A61B5/02427—Details of sensor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Abstract

A tissue modulation device comprises an upper surface and a lower surface, the upper surface comprises a recessed region (920) adjacent to a raised region (910), wherein application of a first portion of a tissue relative to a second portion of the tissue that is in apposition to the recessed region (920). An optically transparent region of the device is curved at the lower surface to substantially reduce backscattered light in a light path traveling through the optically transparent region to a light collection system.
A method of noninvasive spectroscopic measurement of an analyte in a subject comprises applying tissue of the subject to the tissue modulation device so that the raised region depresses a first portion of tissue relative to a second portion of tissue in apposition to the recessed region; irradiating the tissue in a blood-replete and a blood-depleted state with electromagnetic radiation; and analyzing the collected spectra to determine a concentration of analyte present in the tissue, by determining the difference between the spectra of the blood-replete and blood-depleted states.
CA002315192A 1998-01-27 1999-01-27 Method and device for tissue modulation Expired - Fee Related CA2315192C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7265898P 1998-01-27 1998-01-27
US7271098P 1998-01-27 1998-01-27
US60/072,710 1998-01-27
US60/072,658 1998-01-27
PCT/US1999/001704 WO1999037205A1 (en) 1998-01-27 1999-01-27 Method and device for tissue modulation

Publications (2)

Publication Number Publication Date
CA2315192A1 true CA2315192A1 (en) 1999-07-29
CA2315192C CA2315192C (en) 2008-04-29

Family

ID=26753603

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002315192A Expired - Fee Related CA2315192C (en) 1998-01-27 1999-01-27 Method and device for tissue modulation

Country Status (9)

Country Link
US (1) US6223063B1 (en)
EP (1) EP1051106B1 (en)
JP (1) JP2002500908A (en)
AT (1) ATE275867T1 (en)
AU (1) AU2473699A (en)
CA (1) CA2315192C (en)
DE (1) DE69920170T2 (en)
ES (1) ES2224602T3 (en)
WO (1) WO1999037205A1 (en)

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US20060063993A1 (en) * 2004-08-09 2006-03-23 Dejin Yu Method and apparatus for non-invasive measurement of blood analytes
US20060063991A1 (en) * 2004-08-09 2006-03-23 Dejin Yu Method and apparatus for non-invasive measurement of blood analytes with dynamic spectral calibration
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WO2006127766A1 (en) * 2005-05-25 2006-11-30 Bayer Healthcare Llc Methods of using raman spectral information in determining analyte concentrations
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US7603151B2 (en) * 2006-08-22 2009-10-13 Bayer Healthcare Llc Non-invasive methods of using spectral information in determining analyte concentrations
WO2009137740A1 (en) * 2008-05-09 2009-11-12 Hugh Beckman Medical device for diagnosing and treating anomalous tissue and method for doing the same
US8260402B2 (en) * 2008-06-06 2012-09-04 Longevity Link, Inc. Noninvasive measurement of carotenoids in biological tissue
US20100004518A1 (en) * 2008-07-03 2010-01-07 Masimo Laboratories, Inc. Heat sink for noninvasive medical sensor
US8630691B2 (en) 2008-08-04 2014-01-14 Cercacor Laboratories, Inc. Multi-stream sensor front ends for noninvasive measurement of blood constituents
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Also Published As

Publication number Publication date
DE69920170T2 (en) 2005-09-22
JP2002500908A (en) 2002-01-15
CA2315192C (en) 2008-04-29
DE69920170D1 (en) 2004-10-21
ATE275867T1 (en) 2004-10-15
WO1999037205A1 (en) 1999-07-29
ES2224602T3 (en) 2005-03-01
EP1051106A1 (en) 2000-11-15
WO1999037205A8 (en) 1999-09-02
AU2473699A (en) 1999-08-09
EP1051106B1 (en) 2004-09-15
US6223063B1 (en) 2001-04-24

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