CA2315521A1 - Therapeutic laser device and method including noninvasive subsurface monitoring and controlling means - Google Patents

Therapeutic laser device and method including noninvasive subsurface monitoring and controlling means Download PDF

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Publication number
CA2315521A1
CA2315521A1 CA002315521A CA2315521A CA2315521A1 CA 2315521 A1 CA2315521 A1 CA 2315521A1 CA 002315521 A CA002315521 A CA 002315521A CA 2315521 A CA2315521 A CA 2315521A CA 2315521 A1 CA2315521 A1 CA 2315521A1
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CA
Canada
Prior art keywords
laser light
tissue
visible
infrared
monitoring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002315521A
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French (fr)
Other versions
CA2315521C (en
Inventor
Roger J. Dumoulin-White
Lothar Lilge
Robert A. Weersink
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Theralase Inc
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Theralase Inc
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Filing date
Publication date
Application filed by Theralase Inc filed Critical Theralase Inc
Publication of CA2315521A1 publication Critical patent/CA2315521A1/en
Application granted granted Critical
Publication of CA2315521C publication Critical patent/CA2315521C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0616—Skin treatment other than tanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00057—Light
    • A61B2017/00066—Light intensity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0644—Handheld applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light

Abstract

A method is provided for treating a patient having a disorder, wherein the method includes irradiating a tissue surface of the patient with at least one laser beam, automatically monitoring the tissue, and automatically controlling the at least one laser beam to adjust and/or terminate the treatment in a therapeutically effective manner.
The method noninvasively determines in real-time the irradiance and/or radiant exposure of a target tissue at a predetermined depth below the tissue surface by detecting the radial dependence of light remitted from the tissue surface.
Preferably, the method employs a near-infrared light laser beam and a visible laser light beam in combination. An apparatus for performing the method is also provided.

Claims (25)

1. A method for treating a patient having a disorder, said method comprising:
irradiating a tissue of said patient with a near-infrared laser light having a first therapeutically effective intensity and with a visible laser light having a second therapeutically effective intensity;
automatically monitoring said irradiated tissue; and automatically terminating said irradiating when said monitoring indicates that said near-infrared laser light and said visible laser light have been applied to said tissue in amounts therapeutically effective to treat said disorder.
2. The method of claim 1, wherein said monitoring comprises noninvasively determining subsurface intensity of at least one of said near-infrared laser light and said visible laser light.
3. The method of claim 2, wherein said noninvasive determination comprises analyzing a radial dependence of a diffuse reflectance from said tissue of at least one of said near-infrared laser light and said visible laser light.
4. The method of claim 3, wherein said diffuse reflectance is detected from at least two detection points on a surface of said tissue, and wherein said two detection points are at separate positions along a radius originating at a surface focal point of said laser lights.
5. The method of claim 1, further comprising automatically adjusting an intensity of at least one of said near-infrared laser light and said visible laser light in response to information obtained by said monitoring.
6. The method of claim 1, wherein said treating alleviates pain associated with said disorder.
7. The method of claim 1, wherein said treating speeds healing of injuries associated with said disorder.
8. The method of claim 1, wherein said tissue comprises a musculo-skeletal soft-tissue of said patient.
9. The method of claim 1, wherein said tissue comprises skin of said patient.
10. The method of claim 1, wherein said near-infrared laser light has a wavelength of 750 to 1000 nm.
11. The method of claim 1, wherein said visible laser light has a wavelength of 450 to 749 nm.
12. The method of claim 11, wherein said near-infrared laser light has a wavelength of 750 to 1000 nm.
13. The method of claim 1, wherein said near-infrared laser light has a peak intensity of 0 to 2000 watts/cm2.
14. The method of claim 1, wherein said visible laser light has a peak intensity of 0 to 2000 watts/cm2.
15. The method of claim 14, wherein said near-infrared laser light has a peak intensity of 0 to 2000 watts/cm2.
16. The method of claim 15, wherein said near-infrared laser light has a wavelength of 750 to 1000 nm and said visible laser light has a wavelength of 450 to 749 nm.
17. The method of claim 1, wherein said near-infrared laser light and said visible laser light are pulsed.
18. The method of claim 1, wherein said near-infrared laser light is pulsed at a first frequency and said visible laser light is pulsed at a second frequency different from said first frequency, and wherein signals of said near-infrared laser light and said visible laser light are detected by a common sensor and filtered by frequency.
19. The method of claim 1, wherein said irradiating is terminated when said monitoring indicates that at least one of said near-infrared laser light and said visible laser light has penetrated to a sub-surface region of said tissue in an amount therapeutically effective to treat said disorder.
20. A method for administering a predetermined dose of radiation to a distal target tissue, said method comprising:
irradiating a proximal tissue adjacent said distal target tissue with at least one laser light which penetrates through said proximal tissue to administer radiation to'said distal target tissue;
automatically monitoring said proximal tissue to determine whether to terminate said irradiating, said monitoring comprising detecting a radial dependence of a diffuse reflectance from a surface of said proximal tissue of said at least one laser light; and automatically terminating said irradiating when said monitoring indicates that said predetermined dose of laser light has been applied to said distal target tissue.
21. The method of claim 20, wherein said diffuse reflectance is detected from at least two detection points on said surface of said proximal tissue, and wherein said two detection points are at separate positions along a radius originating at a surface focal point of said at least one laser light.
22. The method of claim 20, further comprising automatically adjusting an intensity of said at least one laser light.
23. The method of claim 20, wherein said predetermined dose is an amount therapeutically effective to treat a disorder.
24. A laser apparatus adapted to perform the method of claim 20, said laser apparatus comprising:
at least one laser;
a power supply in electrical communication with said at least one laser;
at least one detector adapted to detect radiation remitted from two points on said target surface along a radius originating at a focal point of said at least one laser on said proximal tissue; and control logic electronics adapted to automatically adjust an output of said at least one laser based on said remitted radiation detected by said at least one detector.
25. A laser apparatus adapted to perform the method of claim 1, said laser apparatus comprising:
a near-infrared light laser;
a visible light laser;
a power supply in electrical communication with said lasers;
waveguides for guiding beams from said lasers to a common focal point on a surface of a target tissue;
detectors adapted to detect radiation remitted from said target surface along a radius originating at said common focal point; and control logic electronics adapted to automatically adjust an output of said lasers based on said remitted radiation detected by said detectors.
CA2315521A 1999-08-09 2000-08-09 Therapeutic laser device and method including noninvasive subsurface monitoring and controlling means Expired - Lifetime CA2315521C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/370,315 US6413267B1 (en) 1999-08-09 1999-08-09 Therapeutic laser device and method including noninvasive subsurface monitoring and controlling means
US09/370,315 1999-08-09

Publications (2)

Publication Number Publication Date
CA2315521A1 true CA2315521A1 (en) 2001-02-09
CA2315521C CA2315521C (en) 2011-07-05

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Family Applications (1)

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CA2315521A Expired - Lifetime CA2315521C (en) 1999-08-09 2000-08-09 Therapeutic laser device and method including noninvasive subsurface monitoring and controlling means

Country Status (6)

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US (1) US6413267B1 (en)
EP (1) EP1075854B1 (en)
AT (1) ATE281872T1 (en)
CA (1) CA2315521C (en)
DE (1) DE60015667T2 (en)
ES (1) ES2232387T3 (en)

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ES2232387T3 (en) 2005-06-01
EP1075854A2 (en) 2001-02-14
US6413267B1 (en) 2002-07-02
EP1075854A3 (en) 2001-11-14
ATE281872T1 (en) 2004-11-15
EP1075854B1 (en) 2004-11-10
DE60015667D1 (en) 2004-12-16
DE60015667T2 (en) 2005-11-24
CA2315521C (en) 2011-07-05

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