CA2326742A1 - Device for taking up and discharging a defined amount of liquid - Google Patents
Device for taking up and discharging a defined amount of liquid Download PDFInfo
- Publication number
- CA2326742A1 CA2326742A1 CA002326742A CA2326742A CA2326742A1 CA 2326742 A1 CA2326742 A1 CA 2326742A1 CA 002326742 A CA002326742 A CA 002326742A CA 2326742 A CA2326742 A CA 2326742A CA 2326742 A1 CA2326742 A1 CA 2326742A1
- Authority
- CA
- Canada
- Prior art keywords
- capillary
- bellows
- liquid
- taking
- discharging
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
- B01L3/022—Capillary pipettes, i.e. having very small bore
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1058—General features of the devices using the transfer device for another function for mixing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Abstract
The invention relates to a device for receiving and discharging a given amount of liquid, comprising agitating means (2) arranged on one end (E1) of a capillary (1) and a diaphragm (3) in the vicinity of the other end (E2).
Description
Device for taking up and discharging a defined amount of liquid The invention relates to a device for taking up and discharging a defined amount of liquid.
G 88 03 331.7 discloses a pipette, in particular for use in dental technology. In this case, an agitating implement is attached to a suction tube. In the case of the known pipette, the liquid must be sucked into the suction tube by means of a suction device. The amount of liquid sucked in depends on the manner and method of actuation of the suction device. It can vary.
EP 0 569 851 Al describes a pipetting device for the mixing of liquids. In this case, the pipette is connected to a take-up device connected to an eccentric. The device is complex and expensive. It requires, inter alia, a special vacuum line for sucking up the liquid to be pipetted.
JP Patent Abstracts of Japan: 07080331 A discloses a pipette tip with a radially peripheral cover formed onto it.
According to the prior art, a capillary produced from glass is also known for taking up a defined amount of blood. The blood taken up can be forced out of the capillary and transferred into a test tube by means of a rubber bellows or diaphragm which can be fitted onto the capillary. In said test tube, it is stirred with a reagent, usually with the aid of the capillary.
The fitting on of the bellows is laborious. Rupture of the capillary may occur as this takes place. The agitating action which can be produced by the capillary is inadequate.
G 88 03 331.7 discloses a pipette, in particular for use in dental technology. In this case, an agitating implement is attached to a suction tube. In the case of the known pipette, the liquid must be sucked into the suction tube by means of a suction device. The amount of liquid sucked in depends on the manner and method of actuation of the suction device. It can vary.
EP 0 569 851 Al describes a pipetting device for the mixing of liquids. In this case, the pipette is connected to a take-up device connected to an eccentric. The device is complex and expensive. It requires, inter alia, a special vacuum line for sucking up the liquid to be pipetted.
JP Patent Abstracts of Japan: 07080331 A discloses a pipette tip with a radially peripheral cover formed onto it.
According to the prior art, a capillary produced from glass is also known for taking up a defined amount of blood. The blood taken up can be forced out of the capillary and transferred into a test tube by means of a rubber bellows or diaphragm which can be fitted onto the capillary. In said test tube, it is stirred with a reagent, usually with the aid of the capillary.
The fitting on of the bellows is laborious. Rupture of the capillary may occur as this takes place. The agitating action which can be produced by the capillary is inadequate.
The object of the invention is to eliminate the disadvantages of the prior art. In particular, a device for taking up and discharging a defined amount of liquid which is easy to handle and with which an improved agitating action can be achieved is to be specified.
This object is achieved by the features of Claim 1.
Expedient developments emerge from the features of Claims 2 to 9.
According to the invention, the object is achieved by a device for taking up and discharging a defined amount of liquid, an agitating means being provided at one end of a capillary and a bellows being provided in the vicinity of the other end. The device according to the invention is easy to handle. There is no longer any need for a separate bellows to be pushed onto the capillary. The agitating device [sic] which can be produced by the capillary is improved.
The bellows may have an aperture. This makes it possible for the liquid to be automatically sucked into the capillary. The liquid can be forced out of the capillary by keeping the aperture closed and squeezing the bellows.
The agitating means is expediently designed in the form of a hook-like continuation, which may have a tip.
This simplifies and makes possible in particular the so-called "hooking" of blood.
According to a further design feature, the bellows may have an accordion-like arrangement of folds. This makes it easier to squeeze.
The capillary, the bellows and the agitating means may be produced in one piece from plastic. This makes production easier and less costly.
This object is achieved by the features of Claim 1.
Expedient developments emerge from the features of Claims 2 to 9.
According to the invention, the object is achieved by a device for taking up and discharging a defined amount of liquid, an agitating means being provided at one end of a capillary and a bellows being provided in the vicinity of the other end. The device according to the invention is easy to handle. There is no longer any need for a separate bellows to be pushed onto the capillary. The agitating device [sic] which can be produced by the capillary is improved.
The bellows may have an aperture. This makes it possible for the liquid to be automatically sucked into the capillary. The liquid can be forced out of the capillary by keeping the aperture closed and squeezing the bellows.
The agitating means is expediently designed in the form of a hook-like continuation, which may have a tip.
This simplifies and makes possible in particular the so-called "hooking" of blood.
According to a further design feature, the bellows may have an accordion-like arrangement of folds. This makes it easier to squeeze.
The capillary, the bellows and the agitating means may be produced in one piece from plastic. This makes production easier and less costly.
According to a further embodiment, the bellows may be formed onto a tubular receptacle, the tubular receptacle being able to taper in the direction of an opening lying opposite the bellows. A capillary produced from glass is expediently fitted fractionally into the tubular receptacle in the region of the opening. This two-part device is also easy to produce.
It is possible here to resort to commercially available glass capillaries. The glass capillary is protected against the risk of rupture by being embedded in the tubular receptacle.
Further advantages of the invention are explained in more detail on the basis of the exemplary embodiments represented in the drawing, in which:
Figure 1 shows a schematic side view of a first embodiment and Figure 2 shows a detailed view according to Figure 1, Figure 3 shows a schematic cross-sectional view of a second embodiment, Figure 4 shows a first side view according to Figure 3 and Figure 5 shows a second side view according to Figure 3.
In Figures 1 and 2, a hook-like continuation 2 has been injection-moulded onto one end E1 of a capillary 1 produced from plastic. At the other end E2 there is a bellows 3 with an aperture 4. The bellows 3 may have accordion-like folds to make squeezing easier.
The capillary is designed such that it is suitable for taking up a defined amount of liquid, here for taking up 25 ~l of blood. It is advantageously produced in a one-piece form from a transparent, biologically inert plastic of high rupture strength.
A further exemplary embodiment is shown in Figures 3 to 5. Attached to a tube 5, tapering in steps in the direction of an opening O, is the bellows 3 at the end opposite the opening O. In the vicinity of the opening O, the tube 5 has a diameter which allows a capillary 1 produced from glass to be received with a frictional fit. The hook-like continuation 2 is provided in the vicinity of the opening O. The bellows 3 and the hook like continuation 2 are advantageously produced with the tube 5 in a one-piece form from injection-moulded plastic.
The function of the device is as follows:
For taking up liquid, for example blood, one end E1 of the capillary is brought into contact with the liquid.
The liquid is taken up in the capillary 1, up to a certain height, by capillary forces. The capillary is advantageously filled completely with blood. The air displaced from the capillary 1 as this happens escapes via the aperture 4.
For discharging the liquid taken up in the capillary 1, the aperture 4 is closed, for example with the thumb.
Pressure on the flexible bellows 3 causes the liquid to be forced out of the capillary 1.
The liquid can be effectively stirred with a reagent in a test tube by means of the hook-like continuation 2.
List of designations 1 capillary 2 hook-like continuation 3 bellows 4 aperture tube E1 end E2 other end O opening
It is possible here to resort to commercially available glass capillaries. The glass capillary is protected against the risk of rupture by being embedded in the tubular receptacle.
Further advantages of the invention are explained in more detail on the basis of the exemplary embodiments represented in the drawing, in which:
Figure 1 shows a schematic side view of a first embodiment and Figure 2 shows a detailed view according to Figure 1, Figure 3 shows a schematic cross-sectional view of a second embodiment, Figure 4 shows a first side view according to Figure 3 and Figure 5 shows a second side view according to Figure 3.
In Figures 1 and 2, a hook-like continuation 2 has been injection-moulded onto one end E1 of a capillary 1 produced from plastic. At the other end E2 there is a bellows 3 with an aperture 4. The bellows 3 may have accordion-like folds to make squeezing easier.
The capillary is designed such that it is suitable for taking up a defined amount of liquid, here for taking up 25 ~l of blood. It is advantageously produced in a one-piece form from a transparent, biologically inert plastic of high rupture strength.
A further exemplary embodiment is shown in Figures 3 to 5. Attached to a tube 5, tapering in steps in the direction of an opening O, is the bellows 3 at the end opposite the opening O. In the vicinity of the opening O, the tube 5 has a diameter which allows a capillary 1 produced from glass to be received with a frictional fit. The hook-like continuation 2 is provided in the vicinity of the opening O. The bellows 3 and the hook like continuation 2 are advantageously produced with the tube 5 in a one-piece form from injection-moulded plastic.
The function of the device is as follows:
For taking up liquid, for example blood, one end E1 of the capillary is brought into contact with the liquid.
The liquid is taken up in the capillary 1, up to a certain height, by capillary forces. The capillary is advantageously filled completely with blood. The air displaced from the capillary 1 as this happens escapes via the aperture 4.
For discharging the liquid taken up in the capillary 1, the aperture 4 is closed, for example with the thumb.
Pressure on the flexible bellows 3 causes the liquid to be forced out of the capillary 1.
The liquid can be effectively stirred with a reagent in a test tube by means of the hook-like continuation 2.
List of designations 1 capillary 2 hook-like continuation 3 bellows 4 aperture tube E1 end E2 other end O opening
Claims (8)
1. Device for taking up and discharging a given amount of liquid, agitating means designed in the form of a hook-like continuation (2) being provided at one end (E1) of a capillary (1) and a bellows (3) being provided in the vicinity of the other end (E2).
2. Device according to Claim 1, the bellows (3) having an aperture (4).
3. Device according to one of the preceding claims, the hook-like continuation (2) having a tip.
4. Device according to one of the preceding claims, the bellows (3) having an accordion-like arrangement of folds.
5. Device according to one of the preceding claims, the capillary (1), the bellows (3) and the agitating means being produced in one piece from plastic.
6. Device according to one of Claims 1 to 4, the bellows (3) being formed onto a tubular receptacle (5).
7. Device according to Claim 6, the tubular receptacle tapering in the direction of an opening (O) lying opposite the bellows (3).
8. Device according to one of Claims 6 or 7, a capillary produced from glass being fitted fractionally into the tubular receptacle (5) in the region of the opening (O).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE29806142.2 | 1998-04-03 | ||
| DE29806142U DE29806142U1 (en) | 1998-04-03 | 1998-04-03 | Device for receiving and dispensing a defined amount of liquid |
| PCT/DE1999/001052 WO1999051350A2 (en) | 1998-04-03 | 1999-03-31 | Device for receiving and discharging a given amount of liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2326742A1 true CA2326742A1 (en) | 1999-10-14 |
Family
ID=8055283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002326742A Abandoned CA2326742A1 (en) | 1998-04-03 | 1999-03-31 | Device for taking up and discharging a defined amount of liquid |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6803021B1 (en) |
| EP (1) | EP1068013B1 (en) |
| AT (1) | ATE242056T1 (en) |
| CA (1) | CA2326742A1 (en) |
| DE (2) | DE29806142U1 (en) |
| WO (1) | WO1999051350A2 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3648487B2 (en) * | 2002-03-01 | 2005-05-18 | アロカ株式会社 | Nozzle tip for dispensing equipment |
| WO2006089252A2 (en) * | 2005-02-16 | 2006-08-24 | Mcneely Michael R | Liquid valving using reactive or responsive materials |
| JP4586130B2 (en) * | 2005-02-22 | 2010-11-24 | 丸石化成株式会社 | Sample liquid collection device |
| RU2509533C2 (en) * | 2008-03-28 | 2014-03-20 | Орион Диагностика Ой | Sampling and dispensing unit |
| US20110129396A1 (en) * | 2009-05-31 | 2011-06-02 | Alere Switzerland Gmbh | Volumetric sampling pipette |
| US8584535B2 (en) * | 2009-09-17 | 2013-11-19 | Innova Prep LLC | Liquid to liquid biological particle concentrator with disposable fluid path |
| WO2014106092A1 (en) * | 2012-12-28 | 2014-07-03 | Access Bio, Inc. | Pipette |
| CN104116513A (en) * | 2013-04-23 | 2014-10-29 | 马荣华 | Self-priming type quantitative micro-quantity blood collection tube |
| CN105498877A (en) * | 2014-12-23 | 2016-04-20 | 马荣华 | Quantitative pipet |
| US20170297013A1 (en) * | 2016-04-14 | 2017-10-19 | Jesse Cohen | Universal Transfer Pipette |
| DE102016109536A1 (en) * | 2016-05-24 | 2017-11-30 | Kabe-Labortechnik Gmbh | Kapillarentleerungshilfe |
| US10814320B2 (en) * | 2016-08-08 | 2020-10-27 | Nalge Nunc International Corporation | Capillary transfer pipettes and related methods |
| WO2020128549A1 (en) * | 2018-12-17 | 2020-06-25 | Pixcell Medical Technologies Ltd. | Devices for extracting a fluid sample from a closed chamber and methods of use thereof |
Family Cites Families (39)
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| US694530A (en) * | 1899-05-25 | 1902-03-04 | Harris Comer | Pipette. |
| US898456A (en) * | 1907-11-13 | 1908-09-15 | Ormsbee T Farnham | Liquid measuring and transferring tube. |
| US2104325A (en) * | 1935-01-28 | 1938-01-04 | Juffa Wilhelm | Mixing pipette |
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| US2982987A (en) * | 1957-08-30 | 1961-05-09 | Tritix Inc | Spreaders for liquids and semi-liquids |
| US2965255A (en) * | 1958-10-09 | 1960-12-20 | Gerarde Horace William | Pipette assembly |
| US3748909A (en) * | 1971-03-10 | 1973-07-31 | M Kuo | Pippette |
| US3772154A (en) | 1971-05-03 | 1973-11-13 | Technicon Instr | Method and apparatus for automated antibiotic susceptibility analysis of bacteria samples |
| US3780992A (en) | 1972-07-17 | 1973-12-25 | Department Of Health Education | Vibrating pipette probe mixer |
| US3834241A (en) * | 1973-04-30 | 1974-09-10 | R Garren | Pipette |
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| DE2901827A1 (en) | 1979-01-18 | 1980-12-11 | Hans Heinlein | Medicine drop bottle - with elastic section in suction tube to reach last remnants |
| US4212204A (en) * | 1979-04-26 | 1980-07-15 | St Amand Elmer F | Pipette and method of making same |
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| US4309912A (en) * | 1980-08-01 | 1982-01-12 | Smith Kendall O | Micro-analysis process and device |
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| DE3701250A1 (en) | 1987-01-17 | 1988-07-28 | Carsten A Carstensen | Dosing pipette |
| US4877585A (en) * | 1987-12-09 | 1989-10-31 | Brandeis University | Dilution pipette device |
| DE8803331U1 (en) * | 1988-03-11 | 1988-04-28 | Kanotscher, Alexander, Braunau, At | |
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| DE4141608C2 (en) * | 1991-12-17 | 1993-12-02 | Eppendorf Geraetebau Netheler | Pipetting device |
| DE9200604U1 (en) | 1992-01-20 | 1992-03-12 | Illing, Gerhard, 6000 Frankfurt, De | |
| ES2110023T3 (en) * | 1992-05-15 | 1998-02-01 | Behring Diagnostics Gmbh | PIPETEO DEVICE. |
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| DE19535046C2 (en) | 1995-09-21 | 1998-04-16 | Eppendorf Geraetebau Netheler | Handheld device for pipetting and photometric measurement of samples |
| USD401698S (en) * | 1997-01-31 | 1998-11-24 | Becton Dickinson And Company | Multistage pipet |
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| US6030582A (en) * | 1998-03-06 | 2000-02-29 | Levy; Abner | Self-resealing, puncturable container cap |
-
1998
- 1998-04-03 DE DE29806142U patent/DE29806142U1/en not_active Expired - Lifetime
-
1999
- 1999-03-31 AT AT99944125T patent/ATE242056T1/en not_active IP Right Cessation
- 1999-03-31 DE DE59905844T patent/DE59905844D1/en not_active Expired - Fee Related
- 1999-03-31 CA CA002326742A patent/CA2326742A1/en not_active Abandoned
- 1999-03-31 EP EP99944125A patent/EP1068013B1/en not_active Expired - Lifetime
- 1999-03-31 US US09/647,618 patent/US6803021B1/en not_active Expired - Fee Related
- 1999-03-31 WO PCT/DE1999/001052 patent/WO1999051350A2/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DE59905844D1 (en) | 2003-07-10 |
| ATE242056T1 (en) | 2003-06-15 |
| DE29806142U1 (en) | 1998-06-18 |
| EP1068013B1 (en) | 2003-06-04 |
| WO1999051350A2 (en) | 1999-10-14 |
| US6803021B1 (en) | 2004-10-12 |
| WO1999051350A3 (en) | 1999-11-18 |
| EP1068013A2 (en) | 2001-01-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |