CA2340651A1 - Shape memory tubular stent - Google Patents
Shape memory tubular stent Download PDFInfo
- Publication number
- CA2340651A1 CA2340651A1 CA002340651A CA2340651A CA2340651A1 CA 2340651 A1 CA2340651 A1 CA 2340651A1 CA 002340651 A CA002340651 A CA 002340651A CA 2340651 A CA2340651 A CA 2340651A CA 2340651 A1 CA2340651 A1 CA 2340651A1
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- Canada
- Prior art keywords
- stent
- deployment system
- elongate member
- catheter
- stent means
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/954—Instruments specially adapted for placement or removal of stents or stent-grafts for placing stents or stent-grafts in a bifurcation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/856—Single tubular stent with a side portal passage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2002/065—Y-shaped blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9505—Instruments specially adapted for placement or removal of stents or stent-grafts having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
- A61F2210/0023—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
- A61F2210/0047—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply heated by light
Abstract
A stent radially expandable from a radially contracted introduction state into a radially expanded position state, in which the final shape of the stent can be controlled by varying the amount and places photo-thermal energy is projected onto the interior surfaces of the tubes from which the stent is fabricated.
Description
SHAPE ~IENIORY TLTBUL:1R STENT
1 t) FIELD OF THE I\~'ENTION
This in invention relates to a stmt for dilating and keeping open vessels.
with a radially contracted state for introduction into the vessel and with a radially expanded stmt at3er introduction into the vessel.
BACKGROUND AND SUMMARY OF IlV'VENTION
Such stems or implantable catheters to be introduced into a body cavity. a vessel or the like can be made tcocn plastic or an inert metal. such as steel or nickel-titanium alloys.
Such stems are also referred to as endovascular or endoluminal stems or endoprostheses.
1 s For example. when dilating the ureter, the stems are used in the prostate region. In the case of benign prostate hvperplasia (BPH) or also in sclerotic blood vessels for dilating and keeping open the same. The stems have material areas and gaps between them.
Thus. it is possible for the wall tissue of the organ kept open to grow round the stmt.
Stems can have a spiral construction. can be in the form of a helicallv wound coil or be in the form ofa mesh fashioned from interconnected ribs. They can be~made from woven or knitted wire or plastic material. Such stems can have memory properties. such as e.g.
exist with certain nickel-titanium (nitinol).
by A method of shaping a hollow tube after it has been placed in the body lumen is W described Unsworth and Waram in a copending patent application, Serial Number 08/749661 tiled on November 15. 1996. which patent application is incorporated herein by specific reference. That patent describes a method of imparting virtually any shape on a shape memow alloy (SVI A) tube. or a tube made of material having similar materials that exhibit shape recoven~ when heated to an appropriate temperature. 'that patent 3o application describes a device comprised of a side-firing laser or electrical probe that selectively heats parts of the inside of a tube of SMA material. Bv shape setting the tube to the desired shape at high temperature. then deforming the tube after it has cooled below the temperature at which it completely yr nearl~~ completely changes into its martensitic phase. one can create many shapes by heating pan or parts of the tube to the 3 ~ temperature at which the selected parts of the material is transformed into its austenitic phase. thus recovering parts of the shape set into the tube at high temperature. That patent application dzscribed how a tube might be transfbrmed into a coil stmt it did not describe how a multiplicity of tubes might be formed info a mesh stmt.
Any number of tubes can be arranged with their longitudinal axes parallel and their sides connec,~ted to each other at various places to form the walls of a larger tube. This larger tube can the be radially expanded by causing the smaller tubes to bend between the points of connection forniing a webbed tubular structure. If the tubas are made of shape memory alloy (SMIA) the larger webbed tube can be heat treated to its shape set temperature and when subsequently cooled below the martet~sitic finish temperature it can be radiallv formed into a more compact structure. .=after the shape setting and deformation steps, the expanded tubular structure can be recovered by heating it above the austenitic finish temperature.
In its compact martensitic forth, the webbed tube can be inserted into the lumen of a tubular body. then heated to support the walls forming the lumen.
The shape of the tubas forming the webbed tubular structure can each be recovered utilizing the method described Unsworth and Waram in a copending patent application.
is Serial Number 08/749661 filed on November 15, 1996. which patent application is incorporated herein by specific reference. This method involves heating the SNiA tubes with photo-thermal energy produced by a laser and delivered down an optical fiber. The photo-tharnial enzrgy is projected to the inside of the tubes at the distal end of the optical fiber by means of side-firing optics attached to the distal end of the fiber or incorporated ~_0 into the distal end of the fiber. The area of projection can be varied depending upon the requirements of the particular application. by means of adjusting the optical side-firing meats. means which are all wall known to practitioners of the art.
As the optical fibers are withdrawn from the tubes. the optical fibers can apply photo-~5 thermal energy to the inside of the tubes or while stationary in the tubes.
Each fiber can be controlled individually. and depending upon whether or not the tube is heated and the shape is thereby recovered at a particular point. the shape of the entire webbed structure can be varied to best effect the purpose.
30 Short webbed tubular structures can be used in combination, being arranged end to end and being slidablv attached olllv by the optical fibers that pass through their lumens. The optical fibers keep the sections of tubular structures aligned. but allow the train of suctions to flex around cun~es in the body lumen. The flexibility of the train can be controlled by varying the ease with which the fibers slide within the lumens of the tube.
Bv this means the train of webbed tubular structures can be mach stiff or ven~
flexible.
depending upon the requirements of the case.
s It can be readily ba seen that the stent fabricated from tubes as described, whether in one piece or a train of sections. offers the advantage of being able to vary the final shape of the stmt by varying the parts of the webbed structure that are recovered. In the case of a train of sections, each can be deployed sequentially and separations between them can be controlled. either in advance. by their placement on the distal end of the catheter. or on the fly. by withdrawing the deliven~ catheter a desired distance. between deployments of the suctions.
Further advantages and features of the invention can be gathered from the claims and description of a preferred embodiment of the invention with reference to the drawings.
BRIEF DESCRIPTION OF DRAWINGS
FIG. I is a perspective view of the preferred embodiment of the stem in its radially contracted low temperature or introduction state. For diagrammatic clarity.
the tubes in the background are drawn with a thinner pen nib that the tubes in the foreground and only four of the eight optical fibers are shown.
FIG. 2 is a perspective view of the same stmt according to the invention in its radially expanded high temperature or use state and shows the delivery catheter and the optical fibers passing from orifices in the delivew catheter to the lumens of'the tubes forming the '?5 stmt.
FIG. 3 is a perspective view of the same stmt as shovm in FIG. 1 and FIG. 2 but with the optical fibers withdrawn from the stmt and just about to be drawn by the operator . into the catheter.
FIG ~ shows the same stmt as shown in FIG. 3 except that the bottom two tubes have not been hilly recovered causing the tubular structure to bend.
FIG. 5 shows a train of stmt sections. slidably attached and aligned by the optical fibers passing through the lumens of the tubes that form the stmt.
FIG. 6 is a perspective view of the same stmt sections as shown in FIG. ~.
except that the Woptical fibers for the distal section, like the proximate section, pass directly from the orifices in the delivery catheter to the lumens of the tubes forming the said stmt section.
FIG. 7 is a perspective view of the same stent sections as shown in FIG. 6 except that one of the tubes is common to both stent sections.
FIG. 8 is a perspective view of the same stent sections as shown in FIG. 7 except that an additional scent section has been connected to one of them for the purpose. of supporting or enlarging bifurcated vessels.
15 FIG. 9 is a perspective view of a device used in combination with a method taught by Unsworth and ~?~'aram in a copending patent application. Serial Number 08:'749661 filed on November 15, 1996 for applying thermal energy to the inside of SMA
tubes to recover parts ofthe shape that was fixed into them at high temperature.
DETAILED DESCRIPTION OF DISCLOSED ENIBODI1~ZENT
In its radiallv contracted state for introduction into the body lumen to be dilated or supported. the stint 1 is a webbed tubular structure or an outer contour as shown in FIG.
I. 'fhe eight tubes 2 are connected at nodal points 3 by welds or other connecting means.
'_'S The stent is delivered into the body lumen at approximately the distal end of a delivery catheter =t to which it is detachably attached. :although the preferred embodiment of the invention shown in FIG. I is comprised of eight tubes. am' number of tubes could comprise the webbed tubular structure.
3U In the radiallv expanded shape as shown on FIG. 2 the tubes 2 have had their shapes recovered by the application of photo-thermal energy delivered by optical fibers S.from a photo-thermal source coupled to the proximal end of the said optical fiber.
The optical fibers that deliver the photo-thermal energy that initiate the shape recovery pass through the delivery catheter and zit it at orifices 6 of the said delivery catheter and thence into the lumens of the tubes 2. The application of photo-thermal energy by means of side-firing optical fibers can be controlled by a method taught by Unsworth and Waram in a copending patent application. Serial Number 081749661 filed on November 1 ~.
1996.
The application of photo-thermal energy to the inside surfaces of the lumens of the said tubes 2 can be accomplished by various procedures. Far example. the side-firing optical fiber can project a narrow beam of photo-thermal energy onto the inside sut-Iace of the lumen of the said tubes 2. in which case the optical fiber typically would be withdrawn gradually from the lumen of the said tubes or individual tubes by the operator and the 1 o shape recover would proceed gradually from one end of the distal end of the tube being recovered to the proximal end of the said tube. W other sample would be a side-firing optical fiber that would project a broad beam onto the entire length ofthe said tube 2. In this second example the entire length of the tube would recover its shape at the same time. A further example would be a side-firing optical fiber that has multiple sidefiring 15 or leaking elements along the fiber at intervals or an end firing optical fiber . Obviously the breadth of the beam projected. the number of beams and the way in which the operator chooses to apply the photo-thermal energy to each tube together or individually make possible many combinations that will be available depending upon the requirements of the procedure at hand.
FIG. 4 chows only one simple example of the control over the final shape of the stent that is possible by varying the application of photo-thermal energy onto the inside surface of individual tubes 2 that comprise the stmt. The effect of reducing the amount of photo-thernial energy on particular tubes that would otherwise be necessary to fully recover the ~5 shape of the tubes is illustrated in FIG. 4 where the tubes 7 and 8 have not fully recovered and thus are straighter than those other fully recovered tubes forming the tubular web stunt. The straighter tubes cause the stmt to bend as illustrated on FIG. 4. This permits tailoring the shape of the stmt to the particular shape of the body h1111e11S lllt0 Whlch It is inserted and expands. It may also ba advantageous to vary ;c) the shape of the stmt prior to its deployment to position it within the body lumen. It should be apparent that the stmt can be shaped in myriad different ways using this technique depending upon the original shapes tined into the SMIa and the parts of the tubes that are heated utilizing the methods L~usworth and ~t'aram in a copending patent application. Serial Number 08'749661 filed on November 1 ~. 1996. which patent application is incorporated herein by specific reference and the device described in that said patent application and illustrated in FIG. 9 is included herein for reference purposes.
s : ~s illustrated in FIG. 5 stmt sections 9 and 10 can be assembled end to end on the delivery catheter ~. Again. for diagrammatic clarity. only four of the optical fibers ~ are shown. rather than one for each of the tubes in the stmt assembly. :although FIG. ~
shows only two sections, additional sections could be added and each section could vary in dimension. including the number of tube meanders. 'the optical fibers that deliver photo-thermal energy to the distal section 10 can either first pass through the proximal section 9 as shown in FIG. 5 or can go directly to a second orifice 12 in the deliven~
catheter a. In the former case the fiber that passes through the distal section 10 can be the same as that which passes through proximal section 9 or it can be a separate optical fiber. The use of a train of smaller stmt sections has several advantages. The principle advantage is that it is more flexible than a single larger section. This makes it easier to deliver to the site of deployment if the lumen into which it was inserted is convoluted.
Another advantage is that spaces can be left between sections that would accommodate vessel side branches. :~s shown on FIG. 5 the sections are slidablv attached by optical fibers 5. The relative sizes of the optical fibers =1 and the lumen of the tubes will determine the resistance to the removal of the optical fiber as it is withdrawn from the tubes. This will also affect the flexibility of the joint formed by the optical fibers between the sections 9 and 10. Thus the flexibility of the joint can be controlled by varying the relative size of the optical fiber and the lumen of the tubes. varying the relative flexibility of the optical fibers to that of the tubes and by varying the length of the separation 11 .5 between the sections 9 and 10. An additional means of increasing the rigidity of the joint between the sections is to continue one or more, of the tubes from one section to the other as shown in FIG. 7 which shows one tube 13 that is continuous between sections 9 and 10. In addition to controlling the flexibility ofthe said joint between the said sections.
these means also assist in aligning the stems with respect to one another.
FIG. 7 also shows a sat of scales or plates 14 that are connected to two tubes 2 to increase the surface area of the stent that comes into contact with the inner surface of the vessel into which the stmt is placed. ~~'hile FIG. 7 depicts only one set of scales. any number of scales could be added to the stunt for this purpose. To accommodate the scales when the stent is in its contracted state, as illustrated in FIG. 1.
the scale ends could interleave or overlap. The scales could also extend over more than one meander.
Thus. It would be possible to cover the entire surface area of the webbed tubular structure with one or more scales.
The stmt sections illustrated in FIG. R address the difficult problem of supporting or enlarging bifurcated or branched vessels. The additional stmt se~~tion 15 is connected by a weld or connecting element 3 to stent section 9, but could a continuation of a tube in to stent section 9. For diagrammatic clarity only four optical fibers 5 are shown running from the orifice 6 in the delivery catheter ~a into the lumens of four of the tubes comprising slant section 15. although in the preferred embodiment each tube comprising stmt section 15 would have an optical fiber to deliver photo-thermal energy to the tube as required. The stent sections 9. 10 and 15 typically would be inserted into the vessel in 15 their compressed state and then stmt sections 10 and 15 would be partly splayed by applying photo-thermal energy at approximately the location of the connection 3 between stmt section 9 and 15. Once partly splayed the stmt assembly could be advanced distally into the vessel and additional photo-thernal energy could be applied to completely splay the said sections 9 and 15 to permit the final distal advancement of the ''0 assemble into the bifurcated vessel. Once the stmt assembly is completely splayed the remainder of the el-panded shape of the entire stem sections could be fitlly recovered as shown in FIG. R. although the above procedure mentions two steps in recovering the splayed shape, any number of incremental steps might be taken to effect the desired result. depending upon the circumstances. As can be readily appreciated any number of ''S stmt assemblies can be connected by means similar to those described to form myriad shapes for various purposes.
In the preferred embodiment of the invention the stem 1 is made from a nickel-titanium alloy. such as Nitinol. although any other material that exhibits shape recoveW on the 30 application ofphoto-thermal energy would be included mthnt the preferred embodiments of the invention. The expanded shape shown in FIG. 2 is heat treated to give the stent memory properties. so that when cooled to its martensitic finish temperature it can be defornied into its radiallv contracted form as showm in FIG. 1. and then when it is heated to its austenitic finish temperature it will recover to its expanded shape shown in FIG. 2.
While the present invention refers to shape memory alloy tubes. sometimes referred to as just tubas. it is to be understood that the invention includes tubes made of other materials that exhibit shape recovery when heated to an appropriate temperature. The references to shape memory alloy should then be considered to be by way of example only of a larger class of materials that exhibit similar properties.
1 n It should also ba understood that while the examples of tubes referred to in this disclosure and in the drawings are cylindrical. it is to be understood that tubes having a cylindrical cross-sectiomare only examples of a larger class of tubes having many different cross-sections for example. triangular. square or star-shaped a combination thereof.
15 It should also be understood that while reference is made to photo-thermal energy being delivered to the tubes. other forms of energy that could be directed down energy guides and that would have the effect of recovering the memorized shape could be substituted.
It should also be understood that a web shape fabricated from tubes is the prefeiTed ~_0 embodiment of the invention. web shapes can be created by weaving the tubes in different configurations. and other shapes can be formed from cotutected tubes that act in like mamer and are included within the invention.
While the present invention has been described in conjunction with preferred ~5 embodiments. it is to be understood that modifications and variations may be resorted to without departing from the spirit and scope of the invention as those skilled in the art will readily understand. Such modifications and variations are considered to be within the pun~iew and scope of the inventions and appended claims.
1 t) FIELD OF THE I\~'ENTION
This in invention relates to a stmt for dilating and keeping open vessels.
with a radially contracted state for introduction into the vessel and with a radially expanded stmt at3er introduction into the vessel.
BACKGROUND AND SUMMARY OF IlV'VENTION
Such stems or implantable catheters to be introduced into a body cavity. a vessel or the like can be made tcocn plastic or an inert metal. such as steel or nickel-titanium alloys.
Such stems are also referred to as endovascular or endoluminal stems or endoprostheses.
1 s For example. when dilating the ureter, the stems are used in the prostate region. In the case of benign prostate hvperplasia (BPH) or also in sclerotic blood vessels for dilating and keeping open the same. The stems have material areas and gaps between them.
Thus. it is possible for the wall tissue of the organ kept open to grow round the stmt.
Stems can have a spiral construction. can be in the form of a helicallv wound coil or be in the form ofa mesh fashioned from interconnected ribs. They can be~made from woven or knitted wire or plastic material. Such stems can have memory properties. such as e.g.
exist with certain nickel-titanium (nitinol).
by A method of shaping a hollow tube after it has been placed in the body lumen is W described Unsworth and Waram in a copending patent application, Serial Number 08/749661 tiled on November 15. 1996. which patent application is incorporated herein by specific reference. That patent describes a method of imparting virtually any shape on a shape memow alloy (SVI A) tube. or a tube made of material having similar materials that exhibit shape recoven~ when heated to an appropriate temperature. 'that patent 3o application describes a device comprised of a side-firing laser or electrical probe that selectively heats parts of the inside of a tube of SMA material. Bv shape setting the tube to the desired shape at high temperature. then deforming the tube after it has cooled below the temperature at which it completely yr nearl~~ completely changes into its martensitic phase. one can create many shapes by heating pan or parts of the tube to the 3 ~ temperature at which the selected parts of the material is transformed into its austenitic phase. thus recovering parts of the shape set into the tube at high temperature. That patent application dzscribed how a tube might be transfbrmed into a coil stmt it did not describe how a multiplicity of tubes might be formed info a mesh stmt.
Any number of tubes can be arranged with their longitudinal axes parallel and their sides connec,~ted to each other at various places to form the walls of a larger tube. This larger tube can the be radially expanded by causing the smaller tubes to bend between the points of connection forniing a webbed tubular structure. If the tubas are made of shape memory alloy (SMIA) the larger webbed tube can be heat treated to its shape set temperature and when subsequently cooled below the martet~sitic finish temperature it can be radiallv formed into a more compact structure. .=after the shape setting and deformation steps, the expanded tubular structure can be recovered by heating it above the austenitic finish temperature.
In its compact martensitic forth, the webbed tube can be inserted into the lumen of a tubular body. then heated to support the walls forming the lumen.
The shape of the tubas forming the webbed tubular structure can each be recovered utilizing the method described Unsworth and Waram in a copending patent application.
is Serial Number 08/749661 filed on November 15, 1996. which patent application is incorporated herein by specific reference. This method involves heating the SNiA tubes with photo-thermal energy produced by a laser and delivered down an optical fiber. The photo-tharnial enzrgy is projected to the inside of the tubes at the distal end of the optical fiber by means of side-firing optics attached to the distal end of the fiber or incorporated ~_0 into the distal end of the fiber. The area of projection can be varied depending upon the requirements of the particular application. by means of adjusting the optical side-firing meats. means which are all wall known to practitioners of the art.
As the optical fibers are withdrawn from the tubes. the optical fibers can apply photo-~5 thermal energy to the inside of the tubes or while stationary in the tubes.
Each fiber can be controlled individually. and depending upon whether or not the tube is heated and the shape is thereby recovered at a particular point. the shape of the entire webbed structure can be varied to best effect the purpose.
30 Short webbed tubular structures can be used in combination, being arranged end to end and being slidablv attached olllv by the optical fibers that pass through their lumens. The optical fibers keep the sections of tubular structures aligned. but allow the train of suctions to flex around cun~es in the body lumen. The flexibility of the train can be controlled by varying the ease with which the fibers slide within the lumens of the tube.
Bv this means the train of webbed tubular structures can be mach stiff or ven~
flexible.
depending upon the requirements of the case.
s It can be readily ba seen that the stent fabricated from tubes as described, whether in one piece or a train of sections. offers the advantage of being able to vary the final shape of the stmt by varying the parts of the webbed structure that are recovered. In the case of a train of sections, each can be deployed sequentially and separations between them can be controlled. either in advance. by their placement on the distal end of the catheter. or on the fly. by withdrawing the deliven~ catheter a desired distance. between deployments of the suctions.
Further advantages and features of the invention can be gathered from the claims and description of a preferred embodiment of the invention with reference to the drawings.
BRIEF DESCRIPTION OF DRAWINGS
FIG. I is a perspective view of the preferred embodiment of the stem in its radially contracted low temperature or introduction state. For diagrammatic clarity.
the tubes in the background are drawn with a thinner pen nib that the tubes in the foreground and only four of the eight optical fibers are shown.
FIG. 2 is a perspective view of the same stmt according to the invention in its radially expanded high temperature or use state and shows the delivery catheter and the optical fibers passing from orifices in the delivew catheter to the lumens of'the tubes forming the '?5 stmt.
FIG. 3 is a perspective view of the same stmt as shovm in FIG. 1 and FIG. 2 but with the optical fibers withdrawn from the stmt and just about to be drawn by the operator . into the catheter.
FIG ~ shows the same stmt as shown in FIG. 3 except that the bottom two tubes have not been hilly recovered causing the tubular structure to bend.
FIG. 5 shows a train of stmt sections. slidably attached and aligned by the optical fibers passing through the lumens of the tubes that form the stmt.
FIG. 6 is a perspective view of the same stmt sections as shown in FIG. ~.
except that the Woptical fibers for the distal section, like the proximate section, pass directly from the orifices in the delivery catheter to the lumens of the tubes forming the said stmt section.
FIG. 7 is a perspective view of the same stent sections as shown in FIG. 6 except that one of the tubes is common to both stent sections.
FIG. 8 is a perspective view of the same stent sections as shown in FIG. 7 except that an additional scent section has been connected to one of them for the purpose. of supporting or enlarging bifurcated vessels.
15 FIG. 9 is a perspective view of a device used in combination with a method taught by Unsworth and ~?~'aram in a copending patent application. Serial Number 08:'749661 filed on November 15, 1996 for applying thermal energy to the inside of SMA
tubes to recover parts ofthe shape that was fixed into them at high temperature.
DETAILED DESCRIPTION OF DISCLOSED ENIBODI1~ZENT
In its radiallv contracted state for introduction into the body lumen to be dilated or supported. the stint 1 is a webbed tubular structure or an outer contour as shown in FIG.
I. 'fhe eight tubes 2 are connected at nodal points 3 by welds or other connecting means.
'_'S The stent is delivered into the body lumen at approximately the distal end of a delivery catheter =t to which it is detachably attached. :although the preferred embodiment of the invention shown in FIG. I is comprised of eight tubes. am' number of tubes could comprise the webbed tubular structure.
3U In the radiallv expanded shape as shown on FIG. 2 the tubes 2 have had their shapes recovered by the application of photo-thermal energy delivered by optical fibers S.from a photo-thermal source coupled to the proximal end of the said optical fiber.
The optical fibers that deliver the photo-thermal energy that initiate the shape recovery pass through the delivery catheter and zit it at orifices 6 of the said delivery catheter and thence into the lumens of the tubes 2. The application of photo-thermal energy by means of side-firing optical fibers can be controlled by a method taught by Unsworth and Waram in a copending patent application. Serial Number 081749661 filed on November 1 ~.
1996.
The application of photo-thermal energy to the inside surfaces of the lumens of the said tubes 2 can be accomplished by various procedures. Far example. the side-firing optical fiber can project a narrow beam of photo-thermal energy onto the inside sut-Iace of the lumen of the said tubes 2. in which case the optical fiber typically would be withdrawn gradually from the lumen of the said tubes or individual tubes by the operator and the 1 o shape recover would proceed gradually from one end of the distal end of the tube being recovered to the proximal end of the said tube. W other sample would be a side-firing optical fiber that would project a broad beam onto the entire length ofthe said tube 2. In this second example the entire length of the tube would recover its shape at the same time. A further example would be a side-firing optical fiber that has multiple sidefiring 15 or leaking elements along the fiber at intervals or an end firing optical fiber . Obviously the breadth of the beam projected. the number of beams and the way in which the operator chooses to apply the photo-thermal energy to each tube together or individually make possible many combinations that will be available depending upon the requirements of the procedure at hand.
FIG. 4 chows only one simple example of the control over the final shape of the stent that is possible by varying the application of photo-thermal energy onto the inside surface of individual tubes 2 that comprise the stmt. The effect of reducing the amount of photo-thernial energy on particular tubes that would otherwise be necessary to fully recover the ~5 shape of the tubes is illustrated in FIG. 4 where the tubes 7 and 8 have not fully recovered and thus are straighter than those other fully recovered tubes forming the tubular web stunt. The straighter tubes cause the stmt to bend as illustrated on FIG. 4. This permits tailoring the shape of the stmt to the particular shape of the body h1111e11S lllt0 Whlch It is inserted and expands. It may also ba advantageous to vary ;c) the shape of the stmt prior to its deployment to position it within the body lumen. It should be apparent that the stmt can be shaped in myriad different ways using this technique depending upon the original shapes tined into the SMIa and the parts of the tubes that are heated utilizing the methods L~usworth and ~t'aram in a copending patent application. Serial Number 08'749661 filed on November 1 ~. 1996. which patent application is incorporated herein by specific reference and the device described in that said patent application and illustrated in FIG. 9 is included herein for reference purposes.
s : ~s illustrated in FIG. 5 stmt sections 9 and 10 can be assembled end to end on the delivery catheter ~. Again. for diagrammatic clarity. only four of the optical fibers ~ are shown. rather than one for each of the tubes in the stmt assembly. :although FIG. ~
shows only two sections, additional sections could be added and each section could vary in dimension. including the number of tube meanders. 'the optical fibers that deliver photo-thermal energy to the distal section 10 can either first pass through the proximal section 9 as shown in FIG. 5 or can go directly to a second orifice 12 in the deliven~
catheter a. In the former case the fiber that passes through the distal section 10 can be the same as that which passes through proximal section 9 or it can be a separate optical fiber. The use of a train of smaller stmt sections has several advantages. The principle advantage is that it is more flexible than a single larger section. This makes it easier to deliver to the site of deployment if the lumen into which it was inserted is convoluted.
Another advantage is that spaces can be left between sections that would accommodate vessel side branches. :~s shown on FIG. 5 the sections are slidablv attached by optical fibers 5. The relative sizes of the optical fibers =1 and the lumen of the tubes will determine the resistance to the removal of the optical fiber as it is withdrawn from the tubes. This will also affect the flexibility of the joint formed by the optical fibers between the sections 9 and 10. Thus the flexibility of the joint can be controlled by varying the relative size of the optical fiber and the lumen of the tubes. varying the relative flexibility of the optical fibers to that of the tubes and by varying the length of the separation 11 .5 between the sections 9 and 10. An additional means of increasing the rigidity of the joint between the sections is to continue one or more, of the tubes from one section to the other as shown in FIG. 7 which shows one tube 13 that is continuous between sections 9 and 10. In addition to controlling the flexibility ofthe said joint between the said sections.
these means also assist in aligning the stems with respect to one another.
FIG. 7 also shows a sat of scales or plates 14 that are connected to two tubes 2 to increase the surface area of the stent that comes into contact with the inner surface of the vessel into which the stmt is placed. ~~'hile FIG. 7 depicts only one set of scales. any number of scales could be added to the stunt for this purpose. To accommodate the scales when the stent is in its contracted state, as illustrated in FIG. 1.
the scale ends could interleave or overlap. The scales could also extend over more than one meander.
Thus. It would be possible to cover the entire surface area of the webbed tubular structure with one or more scales.
The stmt sections illustrated in FIG. R address the difficult problem of supporting or enlarging bifurcated or branched vessels. The additional stmt se~~tion 15 is connected by a weld or connecting element 3 to stent section 9, but could a continuation of a tube in to stent section 9. For diagrammatic clarity only four optical fibers 5 are shown running from the orifice 6 in the delivery catheter ~a into the lumens of four of the tubes comprising slant section 15. although in the preferred embodiment each tube comprising stmt section 15 would have an optical fiber to deliver photo-thermal energy to the tube as required. The stent sections 9. 10 and 15 typically would be inserted into the vessel in 15 their compressed state and then stmt sections 10 and 15 would be partly splayed by applying photo-thermal energy at approximately the location of the connection 3 between stmt section 9 and 15. Once partly splayed the stmt assembly could be advanced distally into the vessel and additional photo-thernal energy could be applied to completely splay the said sections 9 and 15 to permit the final distal advancement of the ''0 assemble into the bifurcated vessel. Once the stmt assembly is completely splayed the remainder of the el-panded shape of the entire stem sections could be fitlly recovered as shown in FIG. R. although the above procedure mentions two steps in recovering the splayed shape, any number of incremental steps might be taken to effect the desired result. depending upon the circumstances. As can be readily appreciated any number of ''S stmt assemblies can be connected by means similar to those described to form myriad shapes for various purposes.
In the preferred embodiment of the invention the stem 1 is made from a nickel-titanium alloy. such as Nitinol. although any other material that exhibits shape recoveW on the 30 application ofphoto-thermal energy would be included mthnt the preferred embodiments of the invention. The expanded shape shown in FIG. 2 is heat treated to give the stent memory properties. so that when cooled to its martensitic finish temperature it can be defornied into its radiallv contracted form as showm in FIG. 1. and then when it is heated to its austenitic finish temperature it will recover to its expanded shape shown in FIG. 2.
While the present invention refers to shape memory alloy tubes. sometimes referred to as just tubas. it is to be understood that the invention includes tubes made of other materials that exhibit shape recovery when heated to an appropriate temperature. The references to shape memory alloy should then be considered to be by way of example only of a larger class of materials that exhibit similar properties.
1 n It should also ba understood that while the examples of tubes referred to in this disclosure and in the drawings are cylindrical. it is to be understood that tubes having a cylindrical cross-sectiomare only examples of a larger class of tubes having many different cross-sections for example. triangular. square or star-shaped a combination thereof.
15 It should also be understood that while reference is made to photo-thermal energy being delivered to the tubes. other forms of energy that could be directed down energy guides and that would have the effect of recovering the memorized shape could be substituted.
It should also be understood that a web shape fabricated from tubes is the prefeiTed ~_0 embodiment of the invention. web shapes can be created by weaving the tubes in different configurations. and other shapes can be formed from cotutected tubes that act in like mamer and are included within the invention.
While the present invention has been described in conjunction with preferred ~5 embodiments. it is to be understood that modifications and variations may be resorted to without departing from the spirit and scope of the invention as those skilled in the art will readily understand. Such modifications and variations are considered to be within the pun~iew and scope of the inventions and appended claims.
Claims (15)
1. A stent deployment system, comprising:
at least one radially expandable stent means (1) having a proximal end, a distal end and a lumen, each said stem means (1) comprising a hollow, generally cylindrical member having a side surface comprising a mesh having a plurality of openings, said mesh being formed by at least one elongate member (2);
delivery means (4) adapted to convey the at least one stem means (1) to a lumen of a vessel; and heating means adapted to heat at least a portion of said at least one elongate member (2) to a temperature above body temperature, said heating means comprising at least one optical fiber (5) adapted to transmit photo-thermal energy;
characterized in that:
said at least one elongate member (2) has a lumen and each said optical fiber (5) extends into the lumen of a respective one of said elongate members (2) to transmit photo-thermal energy onto at least part of an inner surface of the elongate member (2); and said at least one elongate member (2) is comprised of a shape memory alloy having a martensite start temperature less than body temperature and an austenite finish temperature above body temperature, said at least one elongate member (2) having a memorized shape which is recovered when said elongate member (2) is heated to said temperature above body temperature;
wherein transmission of said photothermal energy onto the inner surface of the elongate member (2) by the optical fiber (5) results in heating of at least a portion of the elongate member (2) to said temperature above body temperature to at least partially recover said memorized shape, said memorized shape being selected so that shape recovery of said at least one elongate member (2) results in radial expansion of said at least one stent means (1) inside the lumen of the vessel.
at least one radially expandable stent means (1) having a proximal end, a distal end and a lumen, each said stem means (1) comprising a hollow, generally cylindrical member having a side surface comprising a mesh having a plurality of openings, said mesh being formed by at least one elongate member (2);
delivery means (4) adapted to convey the at least one stem means (1) to a lumen of a vessel; and heating means adapted to heat at least a portion of said at least one elongate member (2) to a temperature above body temperature, said heating means comprising at least one optical fiber (5) adapted to transmit photo-thermal energy;
characterized in that:
said at least one elongate member (2) has a lumen and each said optical fiber (5) extends into the lumen of a respective one of said elongate members (2) to transmit photo-thermal energy onto at least part of an inner surface of the elongate member (2); and said at least one elongate member (2) is comprised of a shape memory alloy having a martensite start temperature less than body temperature and an austenite finish temperature above body temperature, said at least one elongate member (2) having a memorized shape which is recovered when said elongate member (2) is heated to said temperature above body temperature;
wherein transmission of said photothermal energy onto the inner surface of the elongate member (2) by the optical fiber (5) results in heating of at least a portion of the elongate member (2) to said temperature above body temperature to at least partially recover said memorized shape, said memorized shape being selected so that shape recovery of said at least one elongate member (2) results in radial expansion of said at least one stent means (1) inside the lumen of the vessel.
2. The stent deployment system of claim 1, characterized in that said at least one elongate member (2) comprises a plurality of tubular members (2) each having a proximal end and a distal end, the tubular members (2) extending longitudinally along the stent means (1).
3. The stent deployment system of claim 2, characterized in that each of the tubular members (2) is joined at a plurality of points (3) along its length to two other of the tubular members (2).
4. The stent deployment system of claim 3, characterized in that the points (3) are regularly spaced.
5. The scent deployment system of claim 4, characterized in that each of the tubular members (2) defines a regular wave-form having alternating crests and valleys, and wherein the crests of each of the tubular members (2) is joined to the valleys of another of the tubular members (2).
6. The stent deployment system of claim 5, characterized in that each said tubular member (2) has a memorized shape in which a difference in height between the crests and valleys of the wave-form is greater than the difference in height when the stent means (1) is in a radially compressed state.
7. The stent deployment system of claim 1, characterized in that the delivery means (4) comprises a delivery catheter (4) having a proximal end and a distal end, and the at least one stent means (1) is releasably attached to the distal end of the delivery catheter (4), with the distal end fo the catheter extending into the lumen of the at least one stent means (1).
8. The stent deployment system of claim 7, characterized in that each said optical fiber (5) enters the delivery catheter (4) at the proximal end thereof and exits the delivery catheter (4) through an orifice (6) provided in the delivery catheter (4) at a distal end thereof, the orifice (6) being longitudinally spaced from the proximal end of the stent means (1), said catheter (4) having at least one of said orifices (6).
9. The stent deployment system of claim 8, characterized in that the stent means (1) is releasably connected to the delivery catheter (4) by said at least one optical fiber (5), and wherein said at least one optical fiber (5) is retractable into said orifice (6) of the delivery catheter (4) to thereby separate the stent means (1) from the catheter (6).
10. The stent deployment system of claim 8, characterized in that said at least one stent means (1) comprises at least two stent means (9, 10), wherein a first of the stent means (9) is provided longitudinally spaced from a second of the stent means (10), the first stent means (9) being closer to the proximal end of the catheter (4) than the second stent means (10).
11. The stent deployment system of claim 10, characterized in that each of the two stent means (9, 10) is directly connected to the delivery catheter (4) by at least one of said optical fibers (5), and wherein the optical fibers (5) are retractable into the delivery catheter (4) to separate the stent means (9, 10) from the catheter (4).
12. The scent deployment system of claim 10, characterized in that the first stent means (9) is releasably connected to the delivery catheter (4) by said at least one optical fiber (4), and wherein said at least one optical fiber (5) extends through the distal end of the first stent means (9) and into the proximal end of the second stent means (10), thereby releasably connecting the first and second stent means (9, 10) to one another, the at lest one optical fiber (5) being retractable into the delivery catheter (4) to separate the stent means (9, 10) from the catheter (4).
13. The stem deployment system of claim 12, characterized in that the first and second stent means (9, 10) are connected by at least one tubular member 13 extending from the distal end of the first stent means (9) to the proximal end of the second stent means (10).
14. The stent deployment system of claim 3, characterized in that an external surface of the side surface of the stent means (1) is provided with plate means (14) at least partially covering the openings.
15. The stent deployment system of claim 13, characterized in that the stent deployment system is adapted to be received at a branch of said vessel, further comprising a third stent means (15) having a distal end, a proximal end and a lumen, the proximal end of the third stent means (15) positioned at a gap between said first and second stent means (9, 10), said distal end of said catheter (4) extending through said gap outwardly of the lumen of the third scent means (15), such that a longitudinal axis of said third stent means (15) is angled relative to a longitudinal axis of the first and second stent means (9, 10), wherein said third stent means (15) comprises a generally cylindrical member having a side surface comprising a mesh having a plurality of openings, said mesh being formed by at least one elongate member (2) comprised of a material having shape memory characteristics, said at least one elongate member (2) having a memorized shape which is recovered when said elongate member (2) is heated to a temperature above body temperature, wherein said third stent means (15) is releasably connected to said distal end of said catheter (4) by at least one of said optical fibers (5).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/137,953 US6312461B1 (en) | 1998-08-21 | 1998-08-21 | Shape memory tubular stent |
US09/137,953 | 1998-08-21 | ||
PCT/CA1999/000767 WO2000010485A1 (en) | 1998-08-21 | 1999-08-20 | Shape memory tubular stent |
Publications (1)
Publication Number | Publication Date |
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CA2340651A1 true CA2340651A1 (en) | 2000-03-02 |
Family
ID=22479776
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002340651A Abandoned CA2340651A1 (en) | 1998-08-21 | 1999-08-20 | Shape memory tubular stent |
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US (2) | US6312461B1 (en) |
EP (1) | EP1105068A1 (en) |
AU (1) | AU762546B2 (en) |
CA (1) | CA2340651A1 (en) |
WO (1) | WO2000010485A1 (en) |
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1998
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AU762546B2 (en) | 2003-06-26 |
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