CA2345655C - Filter flush system and methods of use - Google Patents
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- CA2345655C CA2345655C CA002345655A CA2345655A CA2345655C CA 2345655 C CA2345655 C CA 2345655C CA 002345655 A CA002345655 A CA 002345655A CA 2345655 A CA2345655 A CA 2345655A CA 2345655 C CA2345655 C CA 2345655C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12136—Balloons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/0108—Both ends closed, i.e. legs gathered at both ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/013—Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2002/018—Filters implantable into blood vessels made from tubes or sheets of material, e.g. by etching or laser-cutting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0006—Rounded shapes, e.g. with rounded corners circular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0067—Three-dimensional shapes conical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0073—Quadric-shaped
- A61F2230/008—Quadric-shaped paraboloidal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0093—Umbrella-shaped, e.g. mushroom-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09175—Guide wires having specific characteristics at the distal tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/06—Body-piercing guide needles or the like
- A61M25/0662—Guide tubes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgical Instruments (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Networks Using Active Elements (AREA)
- Prostheses (AREA)
Abstract
A filter flush system for temporary placement of a filter in an artery or vein is disclosed. The system typically includes a guidewire insertable within a guiding catheter, which has an occlusion balloon disposed about its distal end. The guidewire has an expandable filter, which can be collapsed to pass through a lumen and distal port of the guiding catheter. The lumen is adapted to receive a variety of endovascular devices, including angioplasty, atherectomy, and stenting catheters. Fluid medium or blood can be infused through the lumen of the guiding catheter to flush embolic material or mobile plaque generated during the endovascular procedures toward the expanded filter deployed downstream from the region of interest. Methods of using the filter flush system to entrap and remove embolic material from the vessel are also disclosed.
Description
S P E C I F I C A T I O N
FILTER FLUSH SYSTEM AND METHODS OF USE
Field of the Invention The present invention relates generally to devices and methods useful in capturing embolic material in blood vessels. More specifically, the devices and methods provide a vessel filtering system for temporary deployment in arteries such as the carotid arteries and the aorta, and veins such as the subclavian vein and the superior vena cava.
The system also includes a guidewire for directing endovascular devices, e.g., atherectomy, stent-deployment, or angioplasty catheters, to a region of interest and a guiding catheter with fluid flushing capability to assist in filtering.
Backeround of the Invention Treatment of thrombotic or atherosclerotic lesions in blood vessels using the endovascular approach has recently been proven to be an effective and reliable altetnative to surgical intervention in selected patients. For example, directional atherectomy and percutaneous translumenal coronary angioplasty (PTCA) with or without stent deployment are useful in treating patients with coronary occlusion.
Atherectomy physically removes plaque by cutting, pulverizing, or shaving in atherosclerotic arteries using a catheter-deliverable endarterectomy device.
Angioplasty enlarges the lumenal diameter of a stenotic vessel by exerting mechanical force on the vascular walls. In addition to using the angioplasty, stenting, and/or atherectomy on the coronary vasculature, these endovascular techniques have also proven useful in treating other vascular lesions in, for example, carotid artery stenosis, peripheral arterial occlusive disease (especially the aorta, the iliac artery, and the femoral artery), renal artery stenosis caused by atherosclerosis or fibromuscular disease, superior vena cava syndrome, occlusion iliac vein thrombosis resistant to thrombolysis.
It is well recognized that one of the complications associated with endovascular techniques is the dislodgrnent of embolic materials generated during manipulation of the vessel, thereby causing occlusion of the narrower vessels downstream and ischemia or infarct of the organ which the vessel supplies. In 1995, Waksman et al. disclosed that distal embolization is common after directional atherectomy in coronary arteries and saphenous vein grafts. See tiVaksman et al., American Heart Journal 129(3): 430-5 (1995),. This study found that distal embolization occurs in 28% (31 out of 111) of the patients undergoing atherectomy. In January 1999, Jordan, Jr. et al. disclosed that treatment of carotid stenosis using percutaneous angioplasty with stentin; procedure is associated with more than eight times the rate of microemboli seen using carotid endarterectomy. See Jordan, Jr. et al. Cardiovascular surgery 7(1): 33-8 (1999), ' Microemboli, as detected by transcranial Doppler monitoring in this study, have been shown to be a potential cause of stroke. The embolic materials include calcium, intimal debris, atheromatous plaque, thrombi, and/or air.
There are a number of devices designed to provide blood filtering for entrapment of vascular emboli. The vast majority of these devices are designed for permanent placement in veins to prevent pulmonary embolism. A temporary venous filter
FILTER FLUSH SYSTEM AND METHODS OF USE
Field of the Invention The present invention relates generally to devices and methods useful in capturing embolic material in blood vessels. More specifically, the devices and methods provide a vessel filtering system for temporary deployment in arteries such as the carotid arteries and the aorta, and veins such as the subclavian vein and the superior vena cava.
The system also includes a guidewire for directing endovascular devices, e.g., atherectomy, stent-deployment, or angioplasty catheters, to a region of interest and a guiding catheter with fluid flushing capability to assist in filtering.
Backeround of the Invention Treatment of thrombotic or atherosclerotic lesions in blood vessels using the endovascular approach has recently been proven to be an effective and reliable altetnative to surgical intervention in selected patients. For example, directional atherectomy and percutaneous translumenal coronary angioplasty (PTCA) with or without stent deployment are useful in treating patients with coronary occlusion.
Atherectomy physically removes plaque by cutting, pulverizing, or shaving in atherosclerotic arteries using a catheter-deliverable endarterectomy device.
Angioplasty enlarges the lumenal diameter of a stenotic vessel by exerting mechanical force on the vascular walls. In addition to using the angioplasty, stenting, and/or atherectomy on the coronary vasculature, these endovascular techniques have also proven useful in treating other vascular lesions in, for example, carotid artery stenosis, peripheral arterial occlusive disease (especially the aorta, the iliac artery, and the femoral artery), renal artery stenosis caused by atherosclerosis or fibromuscular disease, superior vena cava syndrome, occlusion iliac vein thrombosis resistant to thrombolysis.
It is well recognized that one of the complications associated with endovascular techniques is the dislodgrnent of embolic materials generated during manipulation of the vessel, thereby causing occlusion of the narrower vessels downstream and ischemia or infarct of the organ which the vessel supplies. In 1995, Waksman et al. disclosed that distal embolization is common after directional atherectomy in coronary arteries and saphenous vein grafts. See tiVaksman et al., American Heart Journal 129(3): 430-5 (1995),. This study found that distal embolization occurs in 28% (31 out of 111) of the patients undergoing atherectomy. In January 1999, Jordan, Jr. et al. disclosed that treatment of carotid stenosis using percutaneous angioplasty with stentin; procedure is associated with more than eight times the rate of microemboli seen using carotid endarterectomy. See Jordan, Jr. et al. Cardiovascular surgery 7(1): 33-8 (1999), ' Microemboli, as detected by transcranial Doppler monitoring in this study, have been shown to be a potential cause of stroke. The embolic materials include calcium, intimal debris, atheromatous plaque, thrombi, and/or air.
There are a number of devices designed to provide blood filtering for entrapment of vascular emboli. The vast majority of these devices are designed for permanent placement in veins to prevent pulmonary embolism. A temporary venous filter
2 device is disclosed in Bajaj, U.S. Patent No. 5,053,008.
The Bajaj device is an intracardiac catheter for temporary placement in the pulmonary trunk of a patient predisposed to pulmonary embolism due to, e.g., hip surgery, major trauma, major abdominal or pelvic surgery, or immobilization. The Bajaj device includes an umbrella made from meshwork which traps venous emboli before they reach the lungs. This device is designed for venous filtration and is not suitable for arterial use because of the hemodynamic differences between arteries and veins.
There are very few intravascular devices designed for arterial use. Arteries are much more flexible and elastic than veins and, in the arteries, blood flow is pulsatile with large pressure variations between systolic and diastolic flow. These pressure variations cause the artery walls to expand and contract. Blood flow rates in the arteries vary from about 1 to about 5 L/min. Ginsburg, U.S. Patent No. 4,873,978, discloses an arterial filtering system, which includes a catheter with a strainer device at its distal end.
This device is inserted into the vessel downstream from the treatment site and, after treatment, the strainer is collapsed around the entrapped emboli and removed from the body. The Ginsburg device could not withstand flow rates of 5 LJmin. It is designed for only small arteries and therefore could not capture emboli destined for all parts of the body. Ing. Walter Hengst GmbH & Co, German Patent DE 34 17 738, also discloses another arterial filter having a folding linkage system which converts the filter from the collapsed to the expanded state.
Filters mounted to the distal end of guidewires have been proposed for intravascular blood filtration. A majority of these devices includes a filter which is
The Bajaj device is an intracardiac catheter for temporary placement in the pulmonary trunk of a patient predisposed to pulmonary embolism due to, e.g., hip surgery, major trauma, major abdominal or pelvic surgery, or immobilization. The Bajaj device includes an umbrella made from meshwork which traps venous emboli before they reach the lungs. This device is designed for venous filtration and is not suitable for arterial use because of the hemodynamic differences between arteries and veins.
There are very few intravascular devices designed for arterial use. Arteries are much more flexible and elastic than veins and, in the arteries, blood flow is pulsatile with large pressure variations between systolic and diastolic flow. These pressure variations cause the artery walls to expand and contract. Blood flow rates in the arteries vary from about 1 to about 5 L/min. Ginsburg, U.S. Patent No. 4,873,978, discloses an arterial filtering system, which includes a catheter with a strainer device at its distal end.
This device is inserted into the vessel downstream from the treatment site and, after treatment, the strainer is collapsed around the entrapped emboli and removed from the body. The Ginsburg device could not withstand flow rates of 5 LJmin. It is designed for only small arteries and therefore could not capture emboli destined for all parts of the body. Ing. Walter Hengst GmbH & Co, German Patent DE 34 17 738, also discloses another arterial filter having a folding linkage system which converts the filter from the collapsed to the expanded state.
Filters mounted to the distal end of guidewires have been proposed for intravascular blood filtration. A majority of these devices includes a filter which is
3 attached to a guidewire and is mechanically actuated via struts or a pre-shaped basket which deploy in the vessel. These filters are typically mesh "parachutes"
which are attached to the shaft of the wire at the distal end and to wire struts which extend outward in a radial direction on the proximal end. The radial struts open the proximal end of the filter to the wall of the vessel. Blood flowing through the vessel is forced through the mesh thereby capturing embolic material in the filter. A major disadvantage associated with these filter devices is that the filters generally rely on vascular blood flow to push debris into the filters. If blood flow in the vessel becomes restricted, the loosely attached embolic material may not be subjected to normal turbulent blood flow. The embolic particles may stay in the vessel proximal to the filter until the higher normal flow is re-established (i.e., when the filter is removed), thereby reducing the efficacy of the filtering devices.
Another means of removing embolic material utilizes temporary occlusion devices, such as balloon occlusion catheters and vascular clamps, to isolate a section of a vessel. After blood flow is isolated in the vessel, fluid or blood within the vessel is aspirated to remove embolic debris. One of the disadvantages associated with occlusion devices is that they require temporary cessation or reduction in distal perfusion that may affect oxygenation of distal organs. Shunts may be placed distal to the devices to maintain perfusion to distal organs. However, insertion of the shunts creates additional trauma to the vessel and may generate additional embolic material.
What is needed are simple and safe blood filtering devices which can be temporarily placed in the arteries and veins and can be used with endovascular instruments to effectively prevent distal embolization. Existing devices are inadequate
which are attached to the shaft of the wire at the distal end and to wire struts which extend outward in a radial direction on the proximal end. The radial struts open the proximal end of the filter to the wall of the vessel. Blood flowing through the vessel is forced through the mesh thereby capturing embolic material in the filter. A major disadvantage associated with these filter devices is that the filters generally rely on vascular blood flow to push debris into the filters. If blood flow in the vessel becomes restricted, the loosely attached embolic material may not be subjected to normal turbulent blood flow. The embolic particles may stay in the vessel proximal to the filter until the higher normal flow is re-established (i.e., when the filter is removed), thereby reducing the efficacy of the filtering devices.
Another means of removing embolic material utilizes temporary occlusion devices, such as balloon occlusion catheters and vascular clamps, to isolate a section of a vessel. After blood flow is isolated in the vessel, fluid or blood within the vessel is aspirated to remove embolic debris. One of the disadvantages associated with occlusion devices is that they require temporary cessation or reduction in distal perfusion that may affect oxygenation of distal organs. Shunts may be placed distal to the devices to maintain perfusion to distal organs. However, insertion of the shunts creates additional trauma to the vessel and may generate additional embolic material.
What is needed are simple and safe blood filtering devices which can be temporarily placed in the arteries and veins and can be used with endovascular instruments to effectively prevent distal embolization. Existing devices are inadequate
4 for this purpose.
Summarv of the Invention Fixed or mobile plaque present in the aorta can dislodge and cause renal infarct or ischemia to other organs. The build up of plaque in the carotid arteries also poses a risk of ischemic stroke by embolization and presents an additional threat of reducing blood flow by occluding the vessel lumen. Plaque present in the iliac and femoral arteries may cause ischemia of the lower extremities, either through distal embolization of atheromatous material or through in situ stenosis of the diseased blood vessel, i.e., narrowing of lumenal diameter. Atherectomy or angioplasty with or without stent deployment in these vessels prevents the above disease from occurring, but can also create these conditions unless the device is specially designed to capture embolic material dislodged during the procedure.
The present invention provides devices and methods for temporary placement of blood filtering capabilities in an artery or vein during endovascular procedures. More specifically, the invention provides a filter flush system which accommodates insertion of endovascular catheters for removing atherosclerotic plaques and/or thrombi and enlarging the lumenal diameter of a stenotic vessel. The filter system also provides means for maintaining distal perfusion during isolation of blood flow, and for pushing embolic debris into the filter during a low-flow state, thereby enhancing filtering capabilities.
In one embodiment, the filter flush system includes an expandable filter, e.g., a parachute, basket, or scroll, mounted on a distal end of a guidewire, and a large
Summarv of the Invention Fixed or mobile plaque present in the aorta can dislodge and cause renal infarct or ischemia to other organs. The build up of plaque in the carotid arteries also poses a risk of ischemic stroke by embolization and presents an additional threat of reducing blood flow by occluding the vessel lumen. Plaque present in the iliac and femoral arteries may cause ischemia of the lower extremities, either through distal embolization of atheromatous material or through in situ stenosis of the diseased blood vessel, i.e., narrowing of lumenal diameter. Atherectomy or angioplasty with or without stent deployment in these vessels prevents the above disease from occurring, but can also create these conditions unless the device is specially designed to capture embolic material dislodged during the procedure.
The present invention provides devices and methods for temporary placement of blood filtering capabilities in an artery or vein during endovascular procedures. More specifically, the invention provides a filter flush system which accommodates insertion of endovascular catheters for removing atherosclerotic plaques and/or thrombi and enlarging the lumenal diameter of a stenotic vessel. The filter system also provides means for maintaining distal perfusion during isolation of blood flow, and for pushing embolic debris into the filter during a low-flow state, thereby enhancing filtering capabilities.
In one embodiment, the filter flush system includes an expandable filter, e.g., a parachute, basket, or scroll, mounted on a distal end of a guidewire, and a large
5 diameter catheter (such as a guiding catheter, angiographic catheter, introducer sheath, vessel dilators) having a lumen communicating with a proximal end and a port at its distal end. The distal end of the catheter is adapted for insertion into an artery or vein.
The proximal end of the catheter may include a hemostatic valve. An expandable occluder, which may comprise an elastomeric balloon, is disposed about the distal end of the guiding catheter and communicates with an inflation lumen for providing isolation of blood flow in the vessel. The lumen of the catheter is adapted to receive the guidewire, which passes through the distal port. A proximal end of the guidewire will typically be operable from outside the proximal end of the catheter for manipulation of the guidewire independently of the catheter. The lumen of the catheter is also adapted to receive an endovascular device, e.g., an angioplasty, stent-deployment, or atherectomy catheter.
The endovascular catheters typically include a proximal end, a distal end and a lumen which receives the guidewire. An excising member, e.g., a cutting blade, abrasive member, wire cutter, jaws, claws, pincher, snare, etc., is included at the distal region of an atherectomy catheter. An expandable balloon is included at a distal region of an angioplasty catheter. An expandable stent is mounted at a distal region of a stent-deployment catheter. The atherectomy catheter may optionally further include means for intravascular imaging, e.g., an ultrasonic transducer. In certain embodiments, the angioplasty catheters include a stent disposed about the balloon at their distal region.
Intravascular imaging devices and stents are fully described in the art and will not be further discussed here.
In another embodiment, the expandable filter comprises an expansion frame and a mesh disposed over the frame. In certain embodiments, the frame comprises
The proximal end of the catheter may include a hemostatic valve. An expandable occluder, which may comprise an elastomeric balloon, is disposed about the distal end of the guiding catheter and communicates with an inflation lumen for providing isolation of blood flow in the vessel. The lumen of the catheter is adapted to receive the guidewire, which passes through the distal port. A proximal end of the guidewire will typically be operable from outside the proximal end of the catheter for manipulation of the guidewire independently of the catheter. The lumen of the catheter is also adapted to receive an endovascular device, e.g., an angioplasty, stent-deployment, or atherectomy catheter.
The endovascular catheters typically include a proximal end, a distal end and a lumen which receives the guidewire. An excising member, e.g., a cutting blade, abrasive member, wire cutter, jaws, claws, pincher, snare, etc., is included at the distal region of an atherectomy catheter. An expandable balloon is included at a distal region of an angioplasty catheter. An expandable stent is mounted at a distal region of a stent-deployment catheter. The atherectomy catheter may optionally further include means for intravascular imaging, e.g., an ultrasonic transducer. In certain embodiments, the angioplasty catheters include a stent disposed about the balloon at their distal region.
Intravascular imaging devices and stents are fully described in the art and will not be further discussed here.
In another embodiment, the expandable filter comprises an expansion frame and a mesh disposed over the frame. In certain embodiments, the frame comprises
6 a plurality of struts bonded to the guidewire at a first end, and the struts expand radially outward at a second end. The frame may comprise an inflation seal for providing better contact with the vascular walls. The construction and use of expansion means and associated filter mesh have been thoroughly discussed in U. S. Patent No.
5,769,816, Barbut et al.
In still another embodiment, the guiding catheter includes an infusion port proximal to the occlusion balloon. The port conununicates with an infusion lumen in the catheter and is adapted for iinfusion of fluid or pharmaceutical agents. Using the infusion port, the dosage of pharmaceutical agent required to achieve local effect can be reduced compared to administration by systemic route. Side effects, e.g., hemorrhage associated with systemic administration of t-PA, can also be minimized. In certain embodiments, the angioplasty catheter may include an infusion port proximal to the angioplasty balloon and a perfusion port distal to the balloon. The infusion and perfusion port communicate, respectively, with an infusion and perfusion lumen included in the angioplasty catheter.
The infusion port is adapted for aspiration of fluid, blood, air, or vascular debris.
The methods of the present invention include protecting a patient from embolization during an endovascular procedure to remove plaque and/or thrombi from the coronary artery, aorta, common carotid artery, external and internal carotid arteries,
5,769,816, Barbut et al.
In still another embodiment, the guiding catheter includes an infusion port proximal to the occlusion balloon. The port conununicates with an infusion lumen in the catheter and is adapted for iinfusion of fluid or pharmaceutical agents. Using the infusion port, the dosage of pharmaceutical agent required to achieve local effect can be reduced compared to administration by systemic route. Side effects, e.g., hemorrhage associated with systemic administration of t-PA, can also be minimized. In certain embodiments, the angioplasty catheter may include an infusion port proximal to the angioplasty balloon and a perfusion port distal to the balloon. The infusion and perfusion port communicate, respectively, with an infusion and perfusion lumen included in the angioplasty catheter.
The infusion port is adapted for aspiration of fluid, blood, air, or vascular debris.
The methods of the present invention include protecting a patient from embolization during an endovascular procedure to remove plaque and/or thrombi from the coronary artery, aorta, common carotid artery, external and internal carotid arteries,
7 brachiocephalic trunk, middle cerebral artery, basilar artery, subclavian artery, brachial artery, axillary artery, iliac artery, renal artery, femoral artery, popliteal artery, celiac artery, superior mesenteric artery, inferior mesenteric artery, anterior tibial artery, posterior tibial artery, and all other arteries carrying oxygenated blood. The methods also include prevention of distal embolization during an endovascular procedure to remove thrombi and/or foreign bodies in the venous circulation, including the superior vena cava, inferior vena cava, extemal and internal jugular veins, brachiocephalic vein, pulmonary artery, subclavian vein, brachial vein, axillary vein, iliac vein, renal vein, femoral vein, profunda femoris vein, great saphenous vein, portal vein, splenic vein, hepatic vein, and azygous vein.
In a first method of using the filter flush system, the distal end of the guidewire, having the filter in a collapsed state, is inserted through an artery or vein. The filter and the distal region of the guidewire are positioned in the vessel beyond a region of interest, followed by expansion of the filter. The guiding catheter is inserted over the guidewire, and the occlusion balloon is positioned proximal to the region of interest. The distal region of an atherectomy, stent-deployment, or angioplasty catheter is inserted over the guidewire, where the guidewire is carried within the lumen of the guiding catheter, and advanced to the region of interest. The occlusion balloon is then expanded to isolate blood flow in the vessel while the endovascular catheter removes or otherwise treats the stenotic lesion in the vascular lumen. The catheter may then be withdrawn or left in place, and fluid or blood is infused through the lumen of the guiding catheter to flush embolic debris into the expanded filter. In certain embodiments, the fluid is directed as a jet toward the atheroma for the purpose of blasting the atheroma from the wall of the
In a first method of using the filter flush system, the distal end of the guidewire, having the filter in a collapsed state, is inserted through an artery or vein. The filter and the distal region of the guidewire are positioned in the vessel beyond a region of interest, followed by expansion of the filter. The guiding catheter is inserted over the guidewire, and the occlusion balloon is positioned proximal to the region of interest. The distal region of an atherectomy, stent-deployment, or angioplasty catheter is inserted over the guidewire, where the guidewire is carried within the lumen of the guiding catheter, and advanced to the region of interest. The occlusion balloon is then expanded to isolate blood flow in the vessel while the endovascular catheter removes or otherwise treats the stenotic lesion in the vascular lumen. The catheter may then be withdrawn or left in place, and fluid or blood is infused through the lumen of the guiding catheter to flush embolic debris into the expanded filter. In certain embodiments, the fluid is directed as a jet toward the atheroma for the purpose of blasting the atheroma from the wall of the
8 vessel and thereafter into the filter. The steps of inserting the endovascular catheter and infusing fluid to flush embolic debris may be repeated until an adequate lumenal diameter is established. The filter is then collapsed and removed, together with the captured embolic debris, from the vessel by withdrawing the guidewire. The guiding catheter is withdrawn after the occlusion balIoon is deflated.
In another method, after the expanded filter and the guiding catheter are positioned, respectively, in a vessel distal to and proximal from the region of interest, the angioplasty balloon carried by the angioplasty catheter is inflated to dilate the stenotic vascular lumen. Blood, fluid, air, and/or embolic debris present between the occlusion and angioplasty balloon may be aspirated. Altematively, the occlusion balloon may be deflated during the inflation of the angioplasty balloon to allow blood to be aspirated from the proximal port and passed to the perfusion port distal to the angioplasty balloon, thereby maintaining perfusion to the distal organs during angioplasty.
It will be understood that there are several advantages in using the devices and methods disclosed herein for capturing and rernoving embolic debris during endovascular procedures. For example, the filter flush system (1) is particularly suited for temporary filtration of blood in any vessel to entrap embolic debris, thereby minimizing neurologic, cognitive, and cardiac complications associated with distal embolization, (2) can withstand high arterial blood flow for an extended time, (3) includes a mesh that is porous enough to allow adequate blood flow in a blood vessel while capturing mobile emboli, (4) is adapted to accommodate an endovascular catheter with or without imaging device, (5) may remove mobile plaque in a vessel by flushing through the guiding catheter, (6) provides means to maintain perfusion to distal organs
In another method, after the expanded filter and the guiding catheter are positioned, respectively, in a vessel distal to and proximal from the region of interest, the angioplasty balloon carried by the angioplasty catheter is inflated to dilate the stenotic vascular lumen. Blood, fluid, air, and/or embolic debris present between the occlusion and angioplasty balloon may be aspirated. Altematively, the occlusion balloon may be deflated during the inflation of the angioplasty balloon to allow blood to be aspirated from the proximal port and passed to the perfusion port distal to the angioplasty balloon, thereby maintaining perfusion to the distal organs during angioplasty.
It will be understood that there are several advantages in using the devices and methods disclosed herein for capturing and rernoving embolic debris during endovascular procedures. For example, the filter flush system (1) is particularly suited for temporary filtration of blood in any vessel to entrap embolic debris, thereby minimizing neurologic, cognitive, and cardiac complications associated with distal embolization, (2) can withstand high arterial blood flow for an extended time, (3) includes a mesh that is porous enough to allow adequate blood flow in a blood vessel while capturing mobile emboli, (4) is adapted to accommodate an endovascular catheter with or without imaging device, (5) may remove mobile plaque in a vessel by flushing through the guiding catheter, (6) provides means to maintain perfusion to distal organs
9 during endovascular procedures, (7) provide means to administer pharmaceutical agents, e.g., tissue plasminogen activator or nitroglycerin, locally to the region of interest, thereby minimizing side effects associated with systemic administration, and (8) can be used in adult and pediatric patients.
Brief Description of the Drawinss Fig. lA depicts an embodiment of a collapsed filter mounted on a distal region of a guidewire according to the present invention.
Fig. 1B depicts the guidewire and expanded filter of Fig. 1A inserted through a lumen of a guiding catheter.
Fig. 2A depicts the filter system of Fig. 1B inserted into a vessel.
Fig. 2B depicts an atherectomy catheter inserted through the lumen of the guiding catheter of Fig. 2A.
Fig. 2C depicts the filter system of Fig. 2A capturing embolic debris.
Fig. 3A depicts another embodiment of the filter system including an inflation seal on the filter.
Fig. 3B depicts an angioplasty catheter inserted through the lumen of the guiding catheter of Fig. 3A.
Fig. 3C depicts the filter system of Fig. 3A capturing embolic debris.
Fig. 4A depicts another embodiment of the filter system having a basket filter.
Fig. 4B depicts a stent-deployment catheter inserted through the lumen of the guiding catheter of Fig. 4A.
Fig. 4C depicts the filter system of Fig. 4A capturing embolic debris.
Fig. 5 depicts another embodiment of the guiding catheter having an infusion port proximal to the occlusion balloon.
Detailed Description In a first embodiment, a filter system for temporary placement in a vessel, either an artery or vein, is provided as depicted in Figs. 1A and 1B. The filter system includes guidewire 10 having a proximal end, distal end 11, and expandable filter 20 mounted at the distal end. The filter comprises umbrella frame 22 and mesh 25 which is sonic welded or adhesive bonded to arms 26 of the umbrella frame.
Anticoagulants, such as heparin and heparinoids, may be applied to mesh 25 to reduce thrombi formation on the mesh. The filter can be collapsed as shown in Fig. lA to facilitate insertion into a vessel, and thereafter expanded as shown in Fig. 1B. A variety of suitable filter guidewires for use herein are described in Tsugita et al., U.S. Patent No.
5,910,154.
The filter system also includes guiding catheter 30 having lumen 33 communicating with a proximal end and distal end 31, and occlusion balloon 40 disposed about the distal end. Balloon 40 communicates with inflation lumen 41, which is adapted to receive fluid or air for expansion of the balloon. Lumen 33 of the catheter communicates with distal port 35 and is adapted to receive guidewire 10 and other therapeutic elements, endovascular devices, such as atherectomy catheters, endovascular imaging devices, stent-deployment catheters, angioplasty catheters, pressure monitors, electrophysiology catheters, and aspirators.
In use, as depicted in Figs. 2A, 2B, and 2C, filter 20 (in the collapsed condition) and distal end 11 of the guidewire is inserted percutaneously through a peripheral artery or vein typically in the direction of blood flow (however, it is contemplated that guidewire 10 may be inserted in a direction opposite the blood flow).
Filter 20 is advanced distal to atheromatous plaque 100 and expanded to contact the vessel walls 101 as depicted in Fig. 2A. Guiding catheter 30 is then inserted over guidewire 10 until distal port 35 is positioned proximal to plaque 100.
Atherectomy catheter 40, having atherectomy device 42 mounted on a distal region, is inserted within lumen 33 of the catheter and over guidewire 10. Atherectomy device 42 is advanced distal to port 35 of the catheter to a position adjacent plague 100. Occlusion balloon 40 is inflated to isolate blood flow in the vessel, while atherectomy device 42 removes plaque 100 as depicted in Fig. 2B.
After adequate lumenal size is achieved by atherectomy, occlusion balloon 40 is deflated, allowing blood flow to be re-established in the region of interest to push the embolic material generated during the procedure toward filter 20 and to perfuse distal organs. Occlusion balloon 40 can be re-inflated to isolate blood flow for repeat atherectomy or other endovascular procedure, e.g., aspiration. After completion of the procedure, the atherectomy catheter is withdrawn from guiding catheter 30 as depicted in Fig. 2C. Fluid or blood is infused through lumen 33 of the guiding catheter to flush the embolic material not cleared as a result of low-flow state toward filter 20.
This may be done with or without balloon 40 deployed. The fluid flush may also be directed at the vessel wall to blast free loosely held atheromatous material which remains after atherectomy. In certain cases, the filter may become loaded with excessive amounts of material. In this case, it may be desirable to deploy a separate aspiration catheter throdgh the guiding catheter to extend distally to the filter, and thereby operate to suction embolic material captured in the mesh. Guidin; catheter 30 is removed from the vessel.
Filter 20 with the captured embolic debris is collapsed and removed from the vessel by withdrawing guidewire 10. The guidewire may altematively be withdrawn into guide catheter 30, and both devices thereafter simultaneously withdrawn. In another embodiment, the guidewire may have a separate capture sheath to assist in its placement and removal by pulling the guidewire into the sheath prior to placement or removal.
By way of example, when the filter system as disclosed herein is intended for use in the aorta, the area of the mesh required for the device is calculated from Bernoulli's equation as described in U. S. Patent No. 5,769,816, Barbut et al.
In an embodiment of the filter flush system that is to be used in the aorta, mesh with dimensions within the following ranges is desirable: mesh area is 0.004-5 in2, more preferably 0.007-4 in2, more preferably 0.010-3 in 2, more preferably 0.0 15-2 in2, more preferably 0.020-1 in2, more preferably 0.025-0.076 in2; mesh thickness is 60-280 m, more preferably 70-270 m, more preferably 80-260 m, more preferably 90-m, more preferably 100-250 m, more preferably 120-230 m, more preferably 140-210 m; thread diameter is 30-145 m, more preferably 40-135 gm, more preferably 50-125 gm, more preferably 60-115 m, more preferably 70-105 m, and pore size is 500 m or less, more preferably 400 m or less, more preferably 300 m or less, more preferably 200 m or less, more preferably 100 m or less, more preferably 50 m or less and usually larger than at least a red blood cell. In a preferred embodiment of the invention, mesh area is 2-8 in 2, mesh thickness is 60-200 m, thread diameter is 30-100 m, and pore size is 50-300 m. In a further preferred embodiment of the invention, mesh area is 3-5 in'`, mesh thickness is 60-150 m, thread diameter is 50=80 m, and pore size is 100-250 m.
In other embodiments, the filter comprises a thin film laser cut with holes to allow blood flow. Typical dimensions include pore size of 20-500 m, a thickness of 0.0005-0.003 inches, and area approximately same as for meshes described above.
Once appropriate physical characteristics are determined, suitable mesh can be found among standard meshes kno-,vn in the art. For example, polyester meshes may be used, such as meshes made by Saati Corporations and Tetko Inc. These are available in sheet form and can be easily cut and formed into a desired shape.
In a preferred embodiment, the mesh is sonic welded into a cone shape. Other meshes known in the art, which have the desired physical characteristics, are also suitable.
Anticoagulants, such as heparin and heparinoids, may be applied to the mesh to reduce the chances of blood clotting on the mesh. Anticoagulants other than heparinoids also may be used, e.g., monoclonal antibodies such as ReoProTM (CentocorTM). The anticoagulant may be painted or sprayed onto the mesh. A chemical dip comprising the anticoagulant also may be used. Other methods known in the art for applying chemicals to mesh may be used.
Figs. 3A, 3B, and 3C depict another embodiment of the filter flush system for temporary placement in a vessel. Mesh 25 of filter 20 is operably connected to inflation seal 27 at a first edge and end plate 28 at a second edge. The inflation seal is expandable between a contracted condition and an enlarged condition. In use, in a contracted condition, inflation sea127 and mesh 25 can be inserted through a peripheral vessel into a region of interest, typically distal to atheromatous plaque 100, as depicted in Fig. 3A. The inflation seal is expanded by injection of fluid or gas to achieve contact with the inner wall of vessel 101. Guiding catheter 30 is inserted over guidewire 10, and distal port 35 is positioned proximal to plaque 100.
Percutaneous translumenal angioplasty has been successful in treating arterial stenosis as well as occlusive venous thrombosis resistant to thrombolysis. See American Heart Journal 125 (2 Pt 1): 362-6 (1993). In Fig. 3B, angioplasty catheter 50, which has angioplasty balloon 52 mounted on a distal region, is inserted through lumen 33 of the guiding catheter over guidewire 10. In a deflated state, the angioplasty balloon is advanced through port 35 to a position adjacent plaque 100. The atheromatous plaque is compressed by inflating balloon 52, thereby dilating the stenosis in the vessel.
In certain embodiments, the angioplasty catheter includes infusion port 54 proximal and perfusion port 55 proximal and distal to balloon 52, respectively. Infusion port 54 may be used to administer pharmaceutical agents, e.g., t-PA or nitroglycerin and to aspirate air, thrombi, plaque, and/or tissue debris. Balloons 40 may be inflated or deflated during angioplasty. Oxygenated medium or blood may be infused through port 55 to provide perfusion to distal organs during angioplasty and facilitate flushing of embolic material into the filter.
In certain embodiments, a prosthesis, such as a stent, is closely associated with the angioplasty balloon. The stent is typically crimped onto the balloon and is capable of controlled radial expansion in a region of interest upon the application of a radial, outwardly extending force from the interior of the stent. The construction of a catheter system carrying a stent is described in detail in Jang et al., U.S.
Pat. No.
5,749,848..
The angioplasty catheter may then be withdrawn from the vessel through lumen 33 of the guiding catheter after completion of angioplasty as depicted in Fig. 3C.
Occlusion balloon 40 is deflated to re-establish blood flow. Before or after deflation of balloon 40, fluid or blood can be infused through lumen 33 and port 35 to flush embolic material into filter 20. After embolic material is captured and retained in the filter, guiding catheter 30 is removed from the vessel. The filter is then contracted by deflating inflation sea127 and, with the captured embolic material, is withdrawn from the vessel and removed from the patient's body.
Another embodiment of the filter flush system is depicted in Figs. 4A, 4B, and 4C. Filter 20 is in the form of a pre-shaped basket, having mesh 25 operably connected to inflation seal 27. The inflation seal can be contracted and expanded by infusing gas or fluid. In use, in a contracted condition, inflation sea127 and mesh 25 are inserted through a peripheral vessel distal to atheromatous plaque 100 as depicted in Fig.
4A. The inflation seal is expanded to contact the inner wall of vessel 101.
Guiding catheter 30 is inserted over guidewire 10, having distal port 35 positioned proximal to plaque 100.
Primary stenting for complex atherosclerotic plaque has been efficacious in treating aortic and iliac stenosis that are not amenable to balloon angioplasty. See Onal, et al., Cardiovascular Interventional Radiology 21(5): 386-92 (1998).
Catheter intervention to the venous system using expandable metallic stents has been successful in treating superior vena cava syndrome which is mainly associated with malignant tumors and is resistant to any other therapy, including balloon angioplasty and surgery. See Na.kanishi, et al., Rinsho Kyoby Geka 14(2): 110-4 (1994). Endovascular catheter 65, which is equipped with self-expanding stent 60 mounted on a distal region, is inserted through lumen 33 of the guiding catheter over guidewire 10 as depicted in Fig.
4B. The stent may be composed of a shape retaining metal, such as nitinol. Catheter 65 will include means for retaining the self-expanding stent. Retaining means may take the form of a sheath disposed about the distal region of the catheter so that the stent is operatively associated with and contained by the sheath, and when the sheath is removed, the stent is released and automatically enlarged to an expanded diameter. Plaque 100 is shown in Figs. 4B and 4C reduced by the self-expanding and thermally activatable stent 60. The construction and deployment of a self-expanding stent is disclosed in Morgentaler, U.S.
Pat. No. 5,224,953. -In Fig. 4C, after stent 60 is deployed over plaque 100, endovascular catheter 65 is removed, leaving lumen 33 of guiding catheter 30 available for infusion of fluid medium. Mobile plaque, which refers to vascular deposits comprising a solidified base and a floppy projection attached to the base which can be dislodged by normal pulsating blood flow, may be found to project through the mesh of stent 60. By flushing fluid through stent 60, the mobile plaque may dislodge and be captured by filter 20.
After embolic material is captured and retained in the filter, guiding catheter 30 is removed from the vessel. Filter 20 is contracted, before or after removal of the guiding catheter, by deflating inflation sea127, and with captured embolic material, is withdrawn from the vessel and removed from the patient's body.
Fig. 5 depicts another embodiment of the filter flush system having infusion port 70, which is located proximal to occlusion balloon 40 and communicates with lumen 33 of guiding catheter 30. Port 70 allows fluid intake and blood to flow from the proximal side of the occlusion balloon and exit distal port 35 of the catheter to provide perfusion to distal organs during an endovascular procedure. In certain embodiments, the guiding catheter may include a plurality of infusion ports proximal to the occlusion balloon, and optionally a one-way valve on the infusion port to eliminate retrograde blood flow. In certain embodiments, the guiding catheter may include aspiration port(s) distal to the occlusion balloon for aspirating vascular debris generated during the endovascular procedure.
The length of the guiding catheter and guidewire will generally be between 15 and 200 centimeters, preferably approximately between 50 and 150 centimeters. The inner diameter of the catheter lumen will generally be between 1.0 and 7 millimeters, preferably approximately between 1.5 and 2.6 millimeters. The diarneter of an expanded occlusion balloon will generally be between 1.5 to 50.0 millimeters, preferably approximately between 3.0 and 8.0 millimeters. The foregoing ranges are set forth solely for the purpose of illustrating typical device dimensions. The actual dimensions of a device constructed according to the principles of the present invention may obviously vary outside of the listed ranges without departing from those basic principles.
Although the foregoing invention has, for the purposes of clarity and understanding, been described in some detail by way of illustration and example, it will be obvious that certain changes and modifications may be practiced which will still fall within the scope of the appended claims. For example, it will be understood that any type of expansion frame disclosed herein or in prior applications can be used with any of the therapeutic catheter interventions, even though any given figure might depict only a particular combination. Moreover, occlusion devices other than balloons can be used with any of the embodiments disclosed herein.
Brief Description of the Drawinss Fig. lA depicts an embodiment of a collapsed filter mounted on a distal region of a guidewire according to the present invention.
Fig. 1B depicts the guidewire and expanded filter of Fig. 1A inserted through a lumen of a guiding catheter.
Fig. 2A depicts the filter system of Fig. 1B inserted into a vessel.
Fig. 2B depicts an atherectomy catheter inserted through the lumen of the guiding catheter of Fig. 2A.
Fig. 2C depicts the filter system of Fig. 2A capturing embolic debris.
Fig. 3A depicts another embodiment of the filter system including an inflation seal on the filter.
Fig. 3B depicts an angioplasty catheter inserted through the lumen of the guiding catheter of Fig. 3A.
Fig. 3C depicts the filter system of Fig. 3A capturing embolic debris.
Fig. 4A depicts another embodiment of the filter system having a basket filter.
Fig. 4B depicts a stent-deployment catheter inserted through the lumen of the guiding catheter of Fig. 4A.
Fig. 4C depicts the filter system of Fig. 4A capturing embolic debris.
Fig. 5 depicts another embodiment of the guiding catheter having an infusion port proximal to the occlusion balloon.
Detailed Description In a first embodiment, a filter system for temporary placement in a vessel, either an artery or vein, is provided as depicted in Figs. 1A and 1B. The filter system includes guidewire 10 having a proximal end, distal end 11, and expandable filter 20 mounted at the distal end. The filter comprises umbrella frame 22 and mesh 25 which is sonic welded or adhesive bonded to arms 26 of the umbrella frame.
Anticoagulants, such as heparin and heparinoids, may be applied to mesh 25 to reduce thrombi formation on the mesh. The filter can be collapsed as shown in Fig. lA to facilitate insertion into a vessel, and thereafter expanded as shown in Fig. 1B. A variety of suitable filter guidewires for use herein are described in Tsugita et al., U.S. Patent No.
5,910,154.
The filter system also includes guiding catheter 30 having lumen 33 communicating with a proximal end and distal end 31, and occlusion balloon 40 disposed about the distal end. Balloon 40 communicates with inflation lumen 41, which is adapted to receive fluid or air for expansion of the balloon. Lumen 33 of the catheter communicates with distal port 35 and is adapted to receive guidewire 10 and other therapeutic elements, endovascular devices, such as atherectomy catheters, endovascular imaging devices, stent-deployment catheters, angioplasty catheters, pressure monitors, electrophysiology catheters, and aspirators.
In use, as depicted in Figs. 2A, 2B, and 2C, filter 20 (in the collapsed condition) and distal end 11 of the guidewire is inserted percutaneously through a peripheral artery or vein typically in the direction of blood flow (however, it is contemplated that guidewire 10 may be inserted in a direction opposite the blood flow).
Filter 20 is advanced distal to atheromatous plaque 100 and expanded to contact the vessel walls 101 as depicted in Fig. 2A. Guiding catheter 30 is then inserted over guidewire 10 until distal port 35 is positioned proximal to plaque 100.
Atherectomy catheter 40, having atherectomy device 42 mounted on a distal region, is inserted within lumen 33 of the catheter and over guidewire 10. Atherectomy device 42 is advanced distal to port 35 of the catheter to a position adjacent plague 100. Occlusion balloon 40 is inflated to isolate blood flow in the vessel, while atherectomy device 42 removes plaque 100 as depicted in Fig. 2B.
After adequate lumenal size is achieved by atherectomy, occlusion balloon 40 is deflated, allowing blood flow to be re-established in the region of interest to push the embolic material generated during the procedure toward filter 20 and to perfuse distal organs. Occlusion balloon 40 can be re-inflated to isolate blood flow for repeat atherectomy or other endovascular procedure, e.g., aspiration. After completion of the procedure, the atherectomy catheter is withdrawn from guiding catheter 30 as depicted in Fig. 2C. Fluid or blood is infused through lumen 33 of the guiding catheter to flush the embolic material not cleared as a result of low-flow state toward filter 20.
This may be done with or without balloon 40 deployed. The fluid flush may also be directed at the vessel wall to blast free loosely held atheromatous material which remains after atherectomy. In certain cases, the filter may become loaded with excessive amounts of material. In this case, it may be desirable to deploy a separate aspiration catheter throdgh the guiding catheter to extend distally to the filter, and thereby operate to suction embolic material captured in the mesh. Guidin; catheter 30 is removed from the vessel.
Filter 20 with the captured embolic debris is collapsed and removed from the vessel by withdrawing guidewire 10. The guidewire may altematively be withdrawn into guide catheter 30, and both devices thereafter simultaneously withdrawn. In another embodiment, the guidewire may have a separate capture sheath to assist in its placement and removal by pulling the guidewire into the sheath prior to placement or removal.
By way of example, when the filter system as disclosed herein is intended for use in the aorta, the area of the mesh required for the device is calculated from Bernoulli's equation as described in U. S. Patent No. 5,769,816, Barbut et al.
In an embodiment of the filter flush system that is to be used in the aorta, mesh with dimensions within the following ranges is desirable: mesh area is 0.004-5 in2, more preferably 0.007-4 in2, more preferably 0.010-3 in 2, more preferably 0.0 15-2 in2, more preferably 0.020-1 in2, more preferably 0.025-0.076 in2; mesh thickness is 60-280 m, more preferably 70-270 m, more preferably 80-260 m, more preferably 90-m, more preferably 100-250 m, more preferably 120-230 m, more preferably 140-210 m; thread diameter is 30-145 m, more preferably 40-135 gm, more preferably 50-125 gm, more preferably 60-115 m, more preferably 70-105 m, and pore size is 500 m or less, more preferably 400 m or less, more preferably 300 m or less, more preferably 200 m or less, more preferably 100 m or less, more preferably 50 m or less and usually larger than at least a red blood cell. In a preferred embodiment of the invention, mesh area is 2-8 in 2, mesh thickness is 60-200 m, thread diameter is 30-100 m, and pore size is 50-300 m. In a further preferred embodiment of the invention, mesh area is 3-5 in'`, mesh thickness is 60-150 m, thread diameter is 50=80 m, and pore size is 100-250 m.
In other embodiments, the filter comprises a thin film laser cut with holes to allow blood flow. Typical dimensions include pore size of 20-500 m, a thickness of 0.0005-0.003 inches, and area approximately same as for meshes described above.
Once appropriate physical characteristics are determined, suitable mesh can be found among standard meshes kno-,vn in the art. For example, polyester meshes may be used, such as meshes made by Saati Corporations and Tetko Inc. These are available in sheet form and can be easily cut and formed into a desired shape.
In a preferred embodiment, the mesh is sonic welded into a cone shape. Other meshes known in the art, which have the desired physical characteristics, are also suitable.
Anticoagulants, such as heparin and heparinoids, may be applied to the mesh to reduce the chances of blood clotting on the mesh. Anticoagulants other than heparinoids also may be used, e.g., monoclonal antibodies such as ReoProTM (CentocorTM). The anticoagulant may be painted or sprayed onto the mesh. A chemical dip comprising the anticoagulant also may be used. Other methods known in the art for applying chemicals to mesh may be used.
Figs. 3A, 3B, and 3C depict another embodiment of the filter flush system for temporary placement in a vessel. Mesh 25 of filter 20 is operably connected to inflation seal 27 at a first edge and end plate 28 at a second edge. The inflation seal is expandable between a contracted condition and an enlarged condition. In use, in a contracted condition, inflation sea127 and mesh 25 can be inserted through a peripheral vessel into a region of interest, typically distal to atheromatous plaque 100, as depicted in Fig. 3A. The inflation seal is expanded by injection of fluid or gas to achieve contact with the inner wall of vessel 101. Guiding catheter 30 is inserted over guidewire 10, and distal port 35 is positioned proximal to plaque 100.
Percutaneous translumenal angioplasty has been successful in treating arterial stenosis as well as occlusive venous thrombosis resistant to thrombolysis. See American Heart Journal 125 (2 Pt 1): 362-6 (1993). In Fig. 3B, angioplasty catheter 50, which has angioplasty balloon 52 mounted on a distal region, is inserted through lumen 33 of the guiding catheter over guidewire 10. In a deflated state, the angioplasty balloon is advanced through port 35 to a position adjacent plaque 100. The atheromatous plaque is compressed by inflating balloon 52, thereby dilating the stenosis in the vessel.
In certain embodiments, the angioplasty catheter includes infusion port 54 proximal and perfusion port 55 proximal and distal to balloon 52, respectively. Infusion port 54 may be used to administer pharmaceutical agents, e.g., t-PA or nitroglycerin and to aspirate air, thrombi, plaque, and/or tissue debris. Balloons 40 may be inflated or deflated during angioplasty. Oxygenated medium or blood may be infused through port 55 to provide perfusion to distal organs during angioplasty and facilitate flushing of embolic material into the filter.
In certain embodiments, a prosthesis, such as a stent, is closely associated with the angioplasty balloon. The stent is typically crimped onto the balloon and is capable of controlled radial expansion in a region of interest upon the application of a radial, outwardly extending force from the interior of the stent. The construction of a catheter system carrying a stent is described in detail in Jang et al., U.S.
Pat. No.
5,749,848..
The angioplasty catheter may then be withdrawn from the vessel through lumen 33 of the guiding catheter after completion of angioplasty as depicted in Fig. 3C.
Occlusion balloon 40 is deflated to re-establish blood flow. Before or after deflation of balloon 40, fluid or blood can be infused through lumen 33 and port 35 to flush embolic material into filter 20. After embolic material is captured and retained in the filter, guiding catheter 30 is removed from the vessel. The filter is then contracted by deflating inflation sea127 and, with the captured embolic material, is withdrawn from the vessel and removed from the patient's body.
Another embodiment of the filter flush system is depicted in Figs. 4A, 4B, and 4C. Filter 20 is in the form of a pre-shaped basket, having mesh 25 operably connected to inflation seal 27. The inflation seal can be contracted and expanded by infusing gas or fluid. In use, in a contracted condition, inflation sea127 and mesh 25 are inserted through a peripheral vessel distal to atheromatous plaque 100 as depicted in Fig.
4A. The inflation seal is expanded to contact the inner wall of vessel 101.
Guiding catheter 30 is inserted over guidewire 10, having distal port 35 positioned proximal to plaque 100.
Primary stenting for complex atherosclerotic plaque has been efficacious in treating aortic and iliac stenosis that are not amenable to balloon angioplasty. See Onal, et al., Cardiovascular Interventional Radiology 21(5): 386-92 (1998).
Catheter intervention to the venous system using expandable metallic stents has been successful in treating superior vena cava syndrome which is mainly associated with malignant tumors and is resistant to any other therapy, including balloon angioplasty and surgery. See Na.kanishi, et al., Rinsho Kyoby Geka 14(2): 110-4 (1994). Endovascular catheter 65, which is equipped with self-expanding stent 60 mounted on a distal region, is inserted through lumen 33 of the guiding catheter over guidewire 10 as depicted in Fig.
4B. The stent may be composed of a shape retaining metal, such as nitinol. Catheter 65 will include means for retaining the self-expanding stent. Retaining means may take the form of a sheath disposed about the distal region of the catheter so that the stent is operatively associated with and contained by the sheath, and when the sheath is removed, the stent is released and automatically enlarged to an expanded diameter. Plaque 100 is shown in Figs. 4B and 4C reduced by the self-expanding and thermally activatable stent 60. The construction and deployment of a self-expanding stent is disclosed in Morgentaler, U.S.
Pat. No. 5,224,953. -In Fig. 4C, after stent 60 is deployed over plaque 100, endovascular catheter 65 is removed, leaving lumen 33 of guiding catheter 30 available for infusion of fluid medium. Mobile plaque, which refers to vascular deposits comprising a solidified base and a floppy projection attached to the base which can be dislodged by normal pulsating blood flow, may be found to project through the mesh of stent 60. By flushing fluid through stent 60, the mobile plaque may dislodge and be captured by filter 20.
After embolic material is captured and retained in the filter, guiding catheter 30 is removed from the vessel. Filter 20 is contracted, before or after removal of the guiding catheter, by deflating inflation sea127, and with captured embolic material, is withdrawn from the vessel and removed from the patient's body.
Fig. 5 depicts another embodiment of the filter flush system having infusion port 70, which is located proximal to occlusion balloon 40 and communicates with lumen 33 of guiding catheter 30. Port 70 allows fluid intake and blood to flow from the proximal side of the occlusion balloon and exit distal port 35 of the catheter to provide perfusion to distal organs during an endovascular procedure. In certain embodiments, the guiding catheter may include a plurality of infusion ports proximal to the occlusion balloon, and optionally a one-way valve on the infusion port to eliminate retrograde blood flow. In certain embodiments, the guiding catheter may include aspiration port(s) distal to the occlusion balloon for aspirating vascular debris generated during the endovascular procedure.
The length of the guiding catheter and guidewire will generally be between 15 and 200 centimeters, preferably approximately between 50 and 150 centimeters. The inner diameter of the catheter lumen will generally be between 1.0 and 7 millimeters, preferably approximately between 1.5 and 2.6 millimeters. The diarneter of an expanded occlusion balloon will generally be between 1.5 to 50.0 millimeters, preferably approximately between 3.0 and 8.0 millimeters. The foregoing ranges are set forth solely for the purpose of illustrating typical device dimensions. The actual dimensions of a device constructed according to the principles of the present invention may obviously vary outside of the listed ranges without departing from those basic principles.
Although the foregoing invention has, for the purposes of clarity and understanding, been described in some detail by way of illustration and example, it will be obvious that certain changes and modifications may be practiced which will still fall within the scope of the appended claims. For example, it will be understood that any type of expansion frame disclosed herein or in prior applications can be used with any of the therapeutic catheter interventions, even though any given figure might depict only a particular combination. Moreover, occlusion devices other than balloons can be used with any of the embodiments disclosed herein.
Claims (43)
1. A vessel filtering system, comprising a guiding catheter having a proximal end region, a distal end region, and an internal lumen;
a therapeutic catheter disposed within the internal lumen of the guiding catheter, the therapeutic catheter defining a guidewire lumen;
a guidewire slidably disposed within the guidewire lumen of the therapeutic catheter;
an expandable filter coupled to the guidewire;
an occlusion balloon coupled to the distal end region of the guiding catheter; and a therapeutic element coupled to the therapeutic catheter and positioned distally of the occlusion balloon.
a therapeutic catheter disposed within the internal lumen of the guiding catheter, the therapeutic catheter defining a guidewire lumen;
a guidewire slidably disposed within the guidewire lumen of the therapeutic catheter;
an expandable filter coupled to the guidewire;
an occlusion balloon coupled to the distal end region of the guiding catheter; and a therapeutic element coupled to the therapeutic catheter and positioned distally of the occlusion balloon.
2. The system of claim 1, wherein the therapeutic catheter comprises an atherectomy catheter, and wherein the therapeutic element includes an excising member.
3. The system of claim 1, wherein the therapeutic catheter comprises an angioplasty catheter, and wherein the therapeutic element includes an angioplasty balloon.
4. The system of claim 3, further comprising a stent disposed about the angioplasty catheter.
5. The system of claim 1, wherein the therapeutic catheter comprises a stent delivery catheter, and wherein the therapeutic element includes a self-expanding stent.
6. The system of claim 1, wherein the expandable filter comprises an expansion frame and a mesh disposed over the frame.
7. The system of claim 6, wherein the mesh is woven.
8. The system of claim 6, wherein the mesh comprises a thin film having holes to allow fluid flow.
9. The system of claim 6, wherein the expansion frame comprises a plurality of struts bonded to the guidewire at a first end, and which expands radially outward at a second end.
10. The system of claim 6, wherein the expansion frame comprises an inflation seal.
11. The system of claim 1, wherein the guiding catheter includes an aspiration port distal the occlusion balloon, the aspiration port communicating with an aspiration lumen.
12. The system of claim 1, wherein the occlusion balloon communicates with an inflation lumen.
13. The system of claim 1, wherein the guiding catheter includes an infusion port proximal to the occlusion balloon.
14. The system of claim 13, wherein the infusion port communicates with the internal lumen of the guiding catheter.
15. The system of claim 3, wherein the therapeutic catheter includes an infusion port proximal to the therapeutic element.
16. The system of claim 15, wherein the infusion port communicates with a perfusion port distal the therapeutic element.
17. A use of a vessel filtering system for filtering embolic debris generated in an artery or vein, the system comprising a guidewire insertable into a vessel;
a filter coupled to a distal end of the guidewire, the filter expandable at a position distal to a region of interest in the vessel;
a therapeutic catheter having a lumen insertable over the guidewire;
a guiding catheter having a lumen insertable over the therapeutic catheter;
an occlusion balloon coupled to the guiding catheter, the occlusion balloon ex-pandable at a position proximal to the region of interest to occlude the vessel; and a therapeutic element coupled to the therapeutic catheter, the therapeutic element adapted to do work at the region of interest resulting in generation of embolic debris.
a filter coupled to a distal end of the guidewire, the filter expandable at a position distal to a region of interest in the vessel;
a therapeutic catheter having a lumen insertable over the guidewire;
a guiding catheter having a lumen insertable over the therapeutic catheter;
an occlusion balloon coupled to the guiding catheter, the occlusion balloon ex-pandable at a position proximal to the region of interest to occlude the vessel; and a therapeutic element coupled to the therapeutic catheter, the therapeutic element adapted to do work at the region of interest resulting in generation of embolic debris.
18. The use of claim 17, wherein fluid is infusible through the lumen of the guiding catheter to flush the emoblic debris into the filter.
19. The use of claim 17, wherein the therapeutic catheter comprises an atherectomy catheter, and wherein the therapeutic element includes an excising member.
20. The use of claim 17, wherein the therapeutic catheter comprises an angioplasty catheter, and wherein the therapeutic element includes an angioplasty balloon to dilate a stenosis within the region of interest.
21. The use of claim 20, wherein the vessel filtering system further comprises a stent disposed about the angioplasty catheter, the angioplasty balloon inflatable to cause radial expansion of the stent against the stenosis.
22. The use of claim 17, wherein the therapeutic catheter comprises a stent delivery catheter, and wherein the therapeutic element includes a self-expanding stent.
23. The use of claim 17, wherein the filter comprises an expansion frame and a mesh disposed over the frame.
24. The use of claim 23, wherein the mesh is woven.
25. The use of claim 23, wherein the mesh comprises a thin film having holes to allow fluid flow.
26. The use of claim 23, wherein the expansion frame comprises a plurality of struts bonded to the guidewire at a first end, and which expands radially outward at a second end.
27. The use of claim 23, wherein the expansion frame comprises an inflation seal.
28. The use of claim 17, wherein the guiding catheter includes an aspiration port distal to the occlusion balloon, the aspiration port communicating with an aspiration lumen.
29. The use of claim 17, wherein the occlusion balloon communicates with an inflation lumen.
30. The use of claim 17, wherein the guiding catheter includes an infusion port proximal to the occlusion balloon.
31. The use of claim 30, wherein the infusion port communicates with the internal lumen of the guiding catheter.
32. The use of claim 30, wherein fluid medium or blood is infusible through the infusion port to perfuse distal organs.
33. The use of claim 20, wherein the therapeutic catheter includes an infusion port proximal to the therapeutic element.
34. The use of claim 33, wherein the infusion port communicates with a perfusion port distal to the therapeutic element.
35. The use of claim 33, wherein fluid medium or blood is infusible through the infusion port to perfuse distal organs
36. The use of claim 17, wherein the embolic debris is atheromatous material.
37. The use of claim 17, wherein the vessel is a coronary artery.
38. The use of claim 17, wherein the vessel is a carotid artery.
39. The use of claim 17, wherein the vessel is an internal carotid artery.
40. The use of claim 17, wherein the vessel is a subclavian vein.
41. The use of claim 17, wherein the vessel is an iliac vein.
42. The use of claim 17, wherein the therapeutic catheter comprises a stent-deployment catheter, the stent-deployment catheter comprising a self-expanding within a sheath, the sheath retractable to release the self-expanding sheath at the region of interest.
43. The use of claim 17, wherein the fluid is oxygenated blood.
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PCT/US2000/040560 WO2001010343A1 (en) | 1999-08-04 | 2000-08-03 | Filter flush system and methods of use |
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CA2345655C true CA2345655C (en) | 2008-12-09 |
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Families Citing this family (625)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2254831C (en) * | 1996-05-14 | 2006-10-17 | Embol-X, Inc. | Aortic occluder with associated filter and methods of use during cardiac surgery |
US20050245894A1 (en) * | 1996-05-20 | 2005-11-03 | Medtronic Vascular, Inc. | Methods and apparatuses for drug delivery to an intravascular occlusion |
US6270477B1 (en) * | 1996-05-20 | 2001-08-07 | Percusurge, Inc. | Catheter for emboli containment |
US6251086B1 (en) * | 1999-07-27 | 2001-06-26 | Scimed Life Systems, Inc. | Guide wire with hydrophilically coated tip |
US6974469B2 (en) * | 1997-03-06 | 2005-12-13 | Scimed Life Systems, Inc. | Distal protection device and method |
US5814064A (en) | 1997-03-06 | 1998-09-29 | Scimed Life Systems, Inc. | Distal protection device |
EP0934092A4 (en) * | 1997-03-06 | 2008-03-26 | Boston Scient Scimed Inc | Distal protection device and method |
US6676682B1 (en) * | 1997-05-08 | 2004-01-13 | Scimed Life Systems, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
US5911734A (en) | 1997-05-08 | 1999-06-15 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
US6238389B1 (en) | 1997-09-30 | 2001-05-29 | Boston Scientific Corporation | Deflectable interstitial ablation device |
US6066149A (en) * | 1997-09-30 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot treatment device with distal filter |
DE69838952T2 (en) * | 1997-11-07 | 2009-01-02 | Salviac Ltd. | EMBOLISM PROTECTION DEVICE |
US7491216B2 (en) | 1997-11-07 | 2009-02-17 | Salviac Limited | Filter element with retractable guidewire tip |
US6936060B2 (en) * | 1998-05-13 | 2005-08-30 | Arteria Medical Sciences, Inc. | Apparatus and methods for removing emboli during a surgical procedure |
US6171327B1 (en) * | 1999-02-24 | 2001-01-09 | Scimed Life Systems, Inc. | Intravascular filter and method |
US6355051B1 (en) | 1999-03-04 | 2002-03-12 | Bioguide Consulting, Inc. | Guidewire filter device |
JP2002543877A (en) * | 1999-05-07 | 2002-12-24 | サルヴィアック・リミテッド | Embolism prevention device |
AU3844499A (en) * | 1999-05-07 | 2000-11-21 | Salviac Limited | Improved filter element for embolic protection device |
US6918921B2 (en) * | 1999-05-07 | 2005-07-19 | Salviac Limited | Support frame for an embolic protection device |
US6964672B2 (en) * | 1999-05-07 | 2005-11-15 | Salviac Limited | Support frame for an embolic protection device |
US20030150821A1 (en) * | 1999-07-16 | 2003-08-14 | Bates Mark C. | Emboli filtration system and methods of use |
US6616679B1 (en) | 1999-07-30 | 2003-09-09 | Incept, Llc | Rapid exchange vascular device for emboli and thrombus removal and methods of use |
WO2001008742A1 (en) * | 1999-07-30 | 2001-02-08 | Incept Llc | Vascular filter having articulation region and methods of use in the ascending aorta |
US6620182B1 (en) | 1999-07-30 | 2003-09-16 | Incept Llc | Vascular filter having articulation region and methods of use in the ascending aorta |
US20020022858A1 (en) * | 1999-07-30 | 2002-02-21 | Demond Jackson F. | Vascular device for emboli removal having suspension strut and methods of use |
US7320697B2 (en) * | 1999-07-30 | 2008-01-22 | Boston Scientific Scimed, Inc. | One piece loop and coil |
US6544279B1 (en) | 2000-08-09 | 2003-04-08 | Incept, Llc | Vascular device for emboli, thrombus and foreign body removal and methods of use |
US6371970B1 (en) | 1999-07-30 | 2002-04-16 | Incept Llc | Vascular filter having articulation region and methods of use in the ascending aorta |
US6589263B1 (en) | 1999-07-30 | 2003-07-08 | Incept Llc | Vascular device having one or more articulation regions and methods of use |
US6530939B1 (en) | 1999-07-30 | 2003-03-11 | Incept, Llc | Vascular device having articulation region and methods of use |
US7306618B2 (en) * | 1999-07-30 | 2007-12-11 | Incept Llc | Vascular device for emboli and thrombi removal and methods of use |
US6142987A (en) | 1999-08-03 | 2000-11-07 | Scimed Life Systems, Inc. | Guided filter with support wire and methods of use |
US6168579B1 (en) * | 1999-08-04 | 2001-01-02 | Scimed Life Systems, Inc. | Filter flush system and methods of use |
US6235044B1 (en) * | 1999-08-04 | 2001-05-22 | Scimed Life Systems, Inc. | Percutaneous catheter and guidewire for filtering during ablation of mycardial or vascular tissue |
US6159197A (en) * | 1999-09-17 | 2000-12-12 | Richard R. Heuser | Method and apparatus for treating body tissues and bodily fluid vessels |
US20090093791A1 (en) * | 1999-09-17 | 2009-04-09 | Heuser Richard R | Devices and methods for treating chronic total occlusion |
US20070265563A1 (en) * | 2006-05-11 | 2007-11-15 | Heuser Richard R | Device for treating chronic total occlusion |
US6939361B1 (en) | 1999-09-22 | 2005-09-06 | Nmt Medical, Inc. | Guidewire for a free standing intervascular device having an integral stop mechanism |
US6386199B1 (en) * | 1999-09-29 | 2002-05-14 | David D. Alfery | Perilaryngeal oral airway |
US6488671B1 (en) * | 1999-10-22 | 2002-12-03 | Corazon Technologies, Inc. | Methods for enhancing fluid flow through an obstructed vascular site, and systems and kits for use in practicing the same |
US8414543B2 (en) | 1999-10-22 | 2013-04-09 | Rex Medical, L.P. | Rotational thrombectomy wire with blocking device |
US6217589B1 (en) | 1999-10-27 | 2001-04-17 | Scimed Life Systems, Inc. | Retrieval device made of precursor alloy cable and method of manufacturing |
US6371971B1 (en) | 1999-11-15 | 2002-04-16 | Scimed Life Systems, Inc. | Guidewire filter and methods of use |
US6468262B1 (en) * | 1999-12-02 | 2002-10-22 | Embol-X, Inc. | Buoyant tip aspiration catheter and methods of use |
ATE357878T1 (en) * | 1999-12-22 | 2007-04-15 | Boston Scient Ltd | ENDOLUMINAL OCCLUSION FLUSH CATHETER |
US6575997B1 (en) * | 1999-12-23 | 2003-06-10 | Endovascular Technologies, Inc. | Embolic basket |
US6660021B1 (en) * | 1999-12-23 | 2003-12-09 | Advanced Cardiovascular Systems, Inc. | Intravascular device and system |
US6402771B1 (en) | 1999-12-23 | 2002-06-11 | Guidant Endovascular Solutions | Snare |
US6540722B1 (en) * | 1999-12-30 | 2003-04-01 | Advanced Cardiovascular Systems, Inc. | Embolic protection devices |
US6695813B1 (en) | 1999-12-30 | 2004-02-24 | Advanced Cardiovascular Systems, Inc. | Embolic protection devices |
US6383206B1 (en) * | 1999-12-30 | 2002-05-07 | Advanced Cardiovascular Systems, Inc. | Embolic protection system and method including filtering elements |
US7918820B2 (en) * | 1999-12-30 | 2011-04-05 | Advanced Cardiovascular Systems, Inc. | Device for, and method of, blocking emboli in vessels such as blood arteries |
US6663613B1 (en) | 2000-01-25 | 2003-12-16 | Bacchus Vascular, Inc. | System and methods for clot dissolution |
US6929653B2 (en) * | 2000-12-15 | 2005-08-16 | Medtronic, Inc. | Apparatus and method for replacing aortic valve |
US6419659B1 (en) * | 2000-02-10 | 2002-07-16 | Medventure Technology Corp | Lipid pool aspiration arrangement for the treatment of vulnerable atherosclerosis plaque |
US20040167567A1 (en) * | 2001-03-23 | 2004-08-26 | Cano Gerald G. | Method and apparatus for capturing objects beyond an operative site in medical procedures |
GB2369575A (en) * | 2000-04-20 | 2002-06-05 | Salviac Ltd | An embolic protection system |
ATE396648T1 (en) * | 2000-05-09 | 2008-06-15 | Paieon Inc | SYSTEM AND METHOD FOR THREE-DIMENTIONAL RECONSTRUCTION OF AN ARTERY |
DE60132452T2 (en) * | 2000-05-31 | 2009-01-15 | Fox Hollow Technologies Inc., Redwood City | EMBOLIZING PROTECTION SYSTEM FOR VASCULAR TREATMENTS |
US20030055377A1 (en) * | 2000-06-02 | 2003-03-20 | Avantec Vascular Corporation | Exchangeable catheter |
US6569180B1 (en) | 2000-06-02 | 2003-05-27 | Avantec Vascular Corporation | Catheter having exchangeable balloon |
US7238168B2 (en) * | 2000-06-02 | 2007-07-03 | Avantec Vascular Corporation | Exchangeable catheter |
US8435225B2 (en) * | 2000-06-02 | 2013-05-07 | Fox Hollow Technologies, Inc. | Embolization protection system for vascular procedures |
US6939362B2 (en) * | 2001-11-27 | 2005-09-06 | Advanced Cardiovascular Systems, Inc. | Offset proximal cage for embolic filtering devices |
US6964670B1 (en) * | 2000-07-13 | 2005-11-15 | Advanced Cardiovascular Systems, Inc. | Embolic protection guide wire |
US6527746B1 (en) * | 2000-08-03 | 2003-03-04 | Ev3, Inc. | Back-loading catheter |
US6485501B1 (en) * | 2000-08-11 | 2002-11-26 | Cordis Corporation | Vascular filter system with guidewire and capture mechanism |
IL154433A0 (en) | 2000-08-18 | 2003-09-17 | Atritech Inc | Expandable implant devices for filtering blood flow from atrial appendages |
US6616681B2 (en) | 2000-10-05 | 2003-09-09 | Scimed Life Systems, Inc. | Filter delivery and retrieval device |
US6537294B1 (en) * | 2000-10-17 | 2003-03-25 | Advanced Cardiovascular Systems, Inc. | Delivery systems for embolic filter devices |
US6893451B2 (en) * | 2000-11-09 | 2005-05-17 | Advanced Cardiovascular Systems, Inc. | Apparatus for capturing objects beyond an operative site utilizing a capture device delivered on a medical guide wire |
US6506203B1 (en) * | 2000-12-19 | 2003-01-14 | Advanced Cardiovascular Systems, Inc. | Low profile sheathless embolic protection system |
US6582448B1 (en) * | 2000-12-21 | 2003-06-24 | Advanced Cardiovascular Systems, Inc. | Vessel occlusion device for embolic protection system |
JP5102931B2 (en) * | 2001-01-09 | 2012-12-19 | マイクロベンション インコーポレイテッド | Embolization catheter and system having the catheter |
US6709449B2 (en) * | 2001-01-12 | 2004-03-23 | Mayo Foundation For Medical Education And Research | Stent treatment apparatus and method |
US6663651B2 (en) | 2001-01-16 | 2003-12-16 | Incept Llc | Systems and methods for vascular filter retrieval |
US7169165B2 (en) * | 2001-01-16 | 2007-01-30 | Boston Scientific Scimed, Inc. | Rapid exchange sheath for deployment of medical devices and methods of use |
US6936059B2 (en) * | 2001-01-16 | 2005-08-30 | Scimed Life Systems, Inc. | Endovascular guidewire filter and methods of use |
US6689151B2 (en) * | 2001-01-25 | 2004-02-10 | Scimed Life Systems, Inc. | Variable wall thickness for delivery sheath housing |
US6840950B2 (en) * | 2001-02-20 | 2005-01-11 | Scimed Life Systems, Inc. | Low profile emboli capture device |
US6595980B1 (en) | 2001-02-23 | 2003-07-22 | Coaxia, Inc. | Devices and methods for preventing distal embolization using flow reversal by occlusion of the brachiocephalic artery |
US6974468B2 (en) * | 2001-02-28 | 2005-12-13 | Scimed Life Systems, Inc. | Filter retrieval catheter |
US7226464B2 (en) * | 2001-03-01 | 2007-06-05 | Scimed Life Systems, Inc. | Intravascular filter retrieval device having an actuatable dilator tip |
US20020123755A1 (en) * | 2001-03-01 | 2002-09-05 | Scimed Life Systems, Inc. | Embolic protection filter delivery sheath |
US6537295B2 (en) | 2001-03-06 | 2003-03-25 | Scimed Life Systems, Inc. | Wire and lock mechanism |
US20020128679A1 (en) * | 2001-03-08 | 2002-09-12 | Embol-X, Inc. | Cerebral protection during carotid endarterectomy and methods of use |
US6645223B2 (en) * | 2001-04-30 | 2003-11-11 | Advanced Cardiovascular Systems, Inc. | Deployment and recovery control systems for embolic protection devices |
US7422579B2 (en) * | 2001-05-01 | 2008-09-09 | St. Jude Medical Cardiology Divison, Inc. | Emboli protection devices and related methods of use |
US6830579B2 (en) * | 2001-05-01 | 2004-12-14 | Coaxia, Inc. | Devices and methods for preventing distal embolization using flow reversal and perfusion augmentation within the cerebral vasculature |
US6929652B1 (en) * | 2001-06-01 | 2005-08-16 | Advanced Cardiovascular Systems, Inc. | Delivery and recovery systems having steerability and rapid exchange operating modes for embolic protection systems |
US6783538B2 (en) | 2001-06-18 | 2004-08-31 | Rex Medical, L.P | Removable vein filter |
CA2455349C (en) * | 2001-06-18 | 2011-02-15 | Rex Medical, L.P. | Vein filter |
US7179275B2 (en) * | 2001-06-18 | 2007-02-20 | Rex Medical, L.P. | Vein filter |
US8282668B2 (en) * | 2001-06-18 | 2012-10-09 | Rex Medical, L.P. | Vein filter |
US6623506B2 (en) * | 2001-06-18 | 2003-09-23 | Rex Medical, L.P | Vein filter |
US6793665B2 (en) | 2001-06-18 | 2004-09-21 | Rex Medical, L.P. | Multiple access vein filter |
US6599307B1 (en) * | 2001-06-29 | 2003-07-29 | Advanced Cardiovascular Systems, Inc. | Filter device for embolic protection systems |
US7338510B2 (en) * | 2001-06-29 | 2008-03-04 | Advanced Cardiovascular Systems, Inc. | Variable thickness embolic filtering devices and method of manufacturing the same |
US6951570B2 (en) * | 2001-07-02 | 2005-10-04 | Rubicon Medical, Inc. | Methods, systems, and devices for deploying a filter from a filter device |
US6997939B2 (en) * | 2001-07-02 | 2006-02-14 | Rubicon Medical, Inc. | Methods, systems, and devices for deploying an embolic protection filter |
US6962598B2 (en) * | 2001-07-02 | 2005-11-08 | Rubicon Medical, Inc. | Methods, systems, and devices for providing embolic protection |
JP4326942B2 (en) * | 2001-07-17 | 2009-09-09 | フォックス・ホロー・テクノロジーズ・インコーポレーテッド | Liquid exchange system for local irrigation and aspiration with controlled liquid volume |
US20030023263A1 (en) * | 2001-07-24 | 2003-01-30 | Incept Llc | Apparatus and methods for aspirating emboli |
US6533800B1 (en) * | 2001-07-25 | 2003-03-18 | Coaxia, Inc. | Devices and methods for preventing distal embolization using flow reversal in arteries having collateral blood flow |
US20030023261A1 (en) * | 2001-07-30 | 2003-01-30 | Scimed Life Systems Inc. | Chronic total occlusion device with variable stiffness shaft |
US20030032941A1 (en) * | 2001-08-13 | 2003-02-13 | Boyle William J. | Convertible delivery systems for medical devices |
US6929634B2 (en) * | 2001-08-22 | 2005-08-16 | Gore Enterprise Holdings, Inc. | Apparatus and methods for treating stroke and controlling cerebral flow characteristics |
US7029488B2 (en) * | 2001-08-22 | 2006-04-18 | Gore Enterprise Holdings, Inc. | Mechanical thrombectomy device for use in cerebral vessels |
US6638294B1 (en) | 2001-08-30 | 2003-10-28 | Advanced Cardiovascular Systems, Inc. | Self furling umbrella frame for carotid filter |
US6592606B2 (en) | 2001-08-31 | 2003-07-15 | Advanced Cardiovascular Systems, Inc. | Hinged short cage for an embolic protection device |
US20030050662A1 (en) * | 2001-09-07 | 2003-03-13 | Don Michael T. Anthony | Devices for observing and treating body passages |
US6878151B2 (en) * | 2001-09-27 | 2005-04-12 | Scimed Life Systems, Inc. | Medical retrieval device |
US8262689B2 (en) | 2001-09-28 | 2012-09-11 | Advanced Cardiovascular Systems, Inc. | Embolic filtering devices |
US6755847B2 (en) * | 2001-10-05 | 2004-06-29 | Scimed Life Systems, Inc. | Emboli capturing device and method of manufacture therefor |
US20030069597A1 (en) * | 2001-10-10 | 2003-04-10 | Scimed Life Systems, Inc. | Loading tool |
US20030078614A1 (en) | 2001-10-18 | 2003-04-24 | Amr Salahieh | Vascular embolic filter devices and methods of use therefor |
US6887257B2 (en) | 2001-10-19 | 2005-05-03 | Incept Llc | Vascular embolic filter exchange devices and methods of use thereof |
US20030083692A1 (en) * | 2001-10-29 | 2003-05-01 | Scimed Life Systems, Inc. | Distal protection device and method of use thereof |
US20030109824A1 (en) * | 2001-11-07 | 2003-06-12 | Microvena Corporation | Distal protection device with local drug delivery to maintain patency |
US7438710B2 (en) * | 2001-11-07 | 2008-10-21 | Anderson Kent D | Distal protection device with local drug infusion by physician to maintain patency |
US7594926B2 (en) * | 2001-11-09 | 2009-09-29 | Boston Scientific Scimed, Inc. | Methods, systems and devices for delivering stents |
EP1441666B1 (en) * | 2001-11-09 | 2008-01-23 | Rubicon Medical, Inc. | Stent delivery device with embolic protection |
US6755813B2 (en) | 2001-11-20 | 2004-06-29 | Cleveland Clinic Foundation | Apparatus and method for performing thrombolysis |
US6749619B2 (en) | 2001-11-20 | 2004-06-15 | The Cleveland Clinic Foundation | Apparatus and method for eliminating dislodged thrombus |
WO2003045313A2 (en) | 2001-11-27 | 2003-06-05 | Merck & Co. Inc. | 2-aminoquinoline compounds |
US7153320B2 (en) * | 2001-12-13 | 2006-12-26 | Scimed Life Systems, Inc. | Hydraulic controlled retractable tip filter retrieval catheter |
US6793666B2 (en) * | 2001-12-18 | 2004-09-21 | Scimed Life Systems, Inc. | Distal protection mechanically attached filter cartridge |
US7241304B2 (en) | 2001-12-21 | 2007-07-10 | Advanced Cardiovascular Systems, Inc. | Flexible and conformable embolic filtering devices |
EP1455686A2 (en) * | 2001-12-21 | 2004-09-15 | Salviac Limited | A support frame for an embolic protection device |
US6932830B2 (en) * | 2002-01-10 | 2005-08-23 | Scimed Life Systems, Inc. | Disc shaped filter |
US8647359B2 (en) | 2002-01-10 | 2014-02-11 | Boston Scientific Scimed, Inc. | Distal protection filter |
US20030135162A1 (en) * | 2002-01-17 | 2003-07-17 | Scimed Life Systems, Inc. | Delivery and retrieval manifold for a distal protection filter |
US20030144686A1 (en) * | 2002-01-30 | 2003-07-31 | Embol-X, Inc. | Distal filtration devices and methods of use during aortic procedures |
US6997938B2 (en) * | 2002-02-12 | 2006-02-14 | Scimed Life Systems, Inc. | Embolic protection device |
US7118539B2 (en) * | 2002-02-26 | 2006-10-10 | Scimed Life Systems, Inc. | Articulating guide wire for embolic protection and methods of use |
US6989024B2 (en) * | 2002-02-28 | 2006-01-24 | Counter Clockwise, Inc. | Guidewire loaded stent for delivery through a catheter |
ATE369088T1 (en) * | 2002-03-05 | 2007-08-15 | Salviac Ltd | SYSTEM FOR PROTECTION AGAINST EMBOLIA |
US6773448B2 (en) | 2002-03-08 | 2004-08-10 | Ev3 Inc. | Distal protection devices having controllable wire motion |
US7029440B2 (en) * | 2002-03-13 | 2006-04-18 | Scimed Life Systems, Inc. | Distal protection filter and method of manufacture |
US20030204237A1 (en) * | 2002-04-25 | 2003-10-30 | Mike Krivoruchko | Stent delivery and aspiration catheter |
US8070769B2 (en) | 2002-05-06 | 2011-12-06 | Boston Scientific Scimed, Inc. | Inverted embolic protection filter |
US7060082B2 (en) | 2002-05-06 | 2006-06-13 | Scimed Life Systems, Inc. | Perfusion guidewire in combination with a distal filter |
IE20030353A1 (en) * | 2002-05-10 | 2003-11-26 | Salviac Ltd | An embolic protection system |
US7585309B2 (en) * | 2002-05-16 | 2009-09-08 | Boston Scientific Scimed, Inc. | Aortic filter |
US7001406B2 (en) * | 2002-05-23 | 2006-02-21 | Scimed Life Systems Inc. | Cartridge embolic protection filter and methods of use |
US7959584B2 (en) * | 2002-05-29 | 2011-06-14 | Boston Scientific Scimed, Inc. | Dedicated distal protection guidewires |
US7549974B2 (en) * | 2002-06-01 | 2009-06-23 | The Board Of Trustees Of The Leland Stanford Junior University | Device and method for medical interventions of body lumens |
US7326224B2 (en) * | 2002-06-11 | 2008-02-05 | Boston Scientific Scimed, Inc. | Shaft and wire lock |
US6887258B2 (en) * | 2002-06-26 | 2005-05-03 | Advanced Cardiovascular Systems, Inc. | Embolic filtering devices for bifurcated vessels |
US7172614B2 (en) * | 2002-06-27 | 2007-02-06 | Advanced Cardiovascular Systems, Inc. | Support structures for embolic filtering devices |
US7166120B2 (en) * | 2002-07-12 | 2007-01-23 | Ev3 Inc. | Catheter with occluding cuff |
US7232452B2 (en) * | 2002-07-12 | 2007-06-19 | Ev3 Inc. | Device to create proximal stasis |
US7115138B2 (en) * | 2002-09-04 | 2006-10-03 | Boston Scientific Scimed, Inc. | Sheath tip |
US7174636B2 (en) * | 2002-09-04 | 2007-02-13 | Scimed Life Systems, Inc. | Method of making an embolic filter |
EP1545319A1 (en) * | 2002-09-23 | 2005-06-29 | NMT Medical, Inc. | Loader for prosthetic occluders and methods thereof |
US7331973B2 (en) * | 2002-09-30 | 2008-02-19 | Avdanced Cardiovascular Systems, Inc. | Guide wire with embolic filtering attachment |
US7252675B2 (en) * | 2002-09-30 | 2007-08-07 | Advanced Cardiovascular, Inc. | Embolic filtering devices |
US20040064099A1 (en) * | 2002-09-30 | 2004-04-01 | Chiu Jessica G. | Intraluminal needle injection substance delivery system with filtering capability |
US20040093011A1 (en) * | 2002-10-01 | 2004-05-13 | Scimed Life Systems, Inc. | Embolic protection device with lesion length assessment markers |
US7998163B2 (en) * | 2002-10-03 | 2011-08-16 | Boston Scientific Scimed, Inc. | Expandable retrieval device |
US8468678B2 (en) | 2002-10-02 | 2013-06-25 | Boston Scientific Scimed, Inc. | Expandable retrieval device |
US7481823B2 (en) * | 2002-10-25 | 2009-01-27 | Boston Scientific Scimed, Inc. | Multiple membrane embolic protection filter |
JP2006514846A (en) * | 2002-10-29 | 2006-05-18 | サード ピーコック、ジェームス、シー. | Emboli filter device and related system and method |
US20040088000A1 (en) * | 2002-10-31 | 2004-05-06 | Muller Paul F. | Single-wire expandable cages for embolic filtering devices |
WO2004043293A2 (en) * | 2002-11-13 | 2004-05-27 | Viacor, Inc. | Cardiac valve procedure methods and devices |
US20040102789A1 (en) * | 2002-11-22 | 2004-05-27 | Scimed Life Systems, Inc. | Selectively locking device |
US20040102806A1 (en) * | 2002-11-27 | 2004-05-27 | Scimed Life Systems, Inc. | Intravascular filter monitoring |
US20040116831A1 (en) * | 2002-12-13 | 2004-06-17 | Scimed Life Systems, Inc. | Distal protection guidewire with nitinol core |
US7625389B2 (en) * | 2002-12-30 | 2009-12-01 | Boston Scientific Scimed, Inc. | Embolic protection device |
US20040138693A1 (en) * | 2003-01-14 | 2004-07-15 | Scimed Life Systems, Inc. | Snare retrievable embolic protection filter with guidewire stopper |
US20040138694A1 (en) * | 2003-01-15 | 2004-07-15 | Scimed Life Systems, Inc. | Intravascular filtering membrane and method of making an embolic protection filter device |
US7166088B2 (en) | 2003-01-27 | 2007-01-23 | Heuser Richard R | Catheter introducer system |
US20040147955A1 (en) * | 2003-01-28 | 2004-07-29 | Scimed Life Systems, Inc. | Embolic protection filter having an improved filter frame |
US20040153119A1 (en) * | 2003-01-30 | 2004-08-05 | Kusleika Richard S. | Embolic filters with a distal loop or no loop |
US8361103B2 (en) * | 2003-02-07 | 2013-01-29 | Karla Weaver | Low profile IVC filter |
US7163549B2 (en) * | 2003-02-11 | 2007-01-16 | Boston Scientific Scimed Inc. | Filter membrane manufacturing method |
US7534251B2 (en) * | 2003-02-11 | 2009-05-19 | Boston Scientific Scimed, Inc. | Retrievable IVC filter |
US20040167566A1 (en) * | 2003-02-24 | 2004-08-26 | Scimed Life Systems, Inc. | Apparatus for anchoring an intravascular device along a guidewire |
US7740644B2 (en) | 2003-02-24 | 2010-06-22 | Boston Scientific Scimed, Inc. | Embolic protection filtering device that can be adapted to be advanced over a guidewire |
US6878291B2 (en) * | 2003-02-24 | 2005-04-12 | Scimed Life Systems, Inc. | Flexible tube for cartridge filter |
US7137991B2 (en) * | 2003-02-24 | 2006-11-21 | Scimed Life Systems, Inc. | Multi-wire embolic protection filtering device |
US8591540B2 (en) * | 2003-02-27 | 2013-11-26 | Abbott Cardiovascular Systems Inc. | Embolic filtering devices |
US20040172055A1 (en) * | 2003-02-27 | 2004-09-02 | Huter Scott J. | Embolic filtering devices |
US7658747B2 (en) * | 2003-03-12 | 2010-02-09 | Nmt Medical, Inc. | Medical device for manipulation of a medical implant |
US7131981B2 (en) * | 2003-03-25 | 2006-11-07 | Angiodynamics, Inc. | Device and method for converting a balloon catheter into a cutting balloon catheter |
JP2006521161A (en) * | 2003-03-26 | 2006-09-21 | カーディオマインド インコーポレイティッド | Implant delivery technology |
US20050209672A1 (en) * | 2004-03-02 | 2005-09-22 | Cardiomind, Inc. | Sliding restraint stent delivery systems |
US7163550B2 (en) * | 2003-03-26 | 2007-01-16 | Scimed Life Systems, Inc. | Method for manufacturing medical devices from linear elastic materials while maintaining linear elastic properties |
US20040193179A1 (en) * | 2003-03-26 | 2004-09-30 | Cardiomind, Inc. | Balloon catheter lumen based stent delivery systems |
US7771463B2 (en) * | 2003-03-26 | 2010-08-10 | Ton Dai T | Twist-down implant delivery technologies |
US20040193208A1 (en) * | 2003-03-27 | 2004-09-30 | Scimed Life Systems, Inc. | Radiopaque embolic protection filter membrane |
US6960370B2 (en) * | 2003-03-27 | 2005-11-01 | Scimed Life Systems, Inc. | Methods of forming medical devices |
US20040193023A1 (en) * | 2003-03-28 | 2004-09-30 | Aris Mardirossian | System, method and apparatus for monitoring recording and reporting physiological data |
US20040199201A1 (en) * | 2003-04-02 | 2004-10-07 | Scimed Life Systems, Inc. | Embolectomy devices |
US20040199199A1 (en) * | 2003-04-02 | 2004-10-07 | Scimed Life Systems, Inc. | Filter and method of making a filter |
US6902572B2 (en) * | 2003-04-02 | 2005-06-07 | Scimed Life Systems, Inc. | Anchoring mechanisms for intravascular devices |
US20040204737A1 (en) * | 2003-04-11 | 2004-10-14 | Scimed Life Systems, Inc. | Embolic filter loop fabricated from composite material |
US7331976B2 (en) | 2003-04-29 | 2008-02-19 | Rex Medical, L.P. | Distal protection device |
US7604649B2 (en) * | 2003-04-29 | 2009-10-20 | Rex Medical, L.P. | Distal protection device |
US20040220612A1 (en) * | 2003-04-30 | 2004-11-04 | Swainston Kyle W | Slidable capture catheter |
US7780611B2 (en) * | 2003-05-01 | 2010-08-24 | Boston Scientific Scimed, Inc. | Medical instrument with controlled torque transmission |
US6969396B2 (en) * | 2003-05-07 | 2005-11-29 | Scimed Life Systems, Inc. | Filter membrane with increased surface area |
US8052701B1 (en) * | 2003-06-02 | 2011-11-08 | Abbott Cardiovascular Systems Inc. | Method and apparatus for rupturing a vulnerable plaque |
US20040249409A1 (en) * | 2003-06-09 | 2004-12-09 | Scimed Life Systems, Inc. | Reinforced filter membrane |
US7537600B2 (en) * | 2003-06-12 | 2009-05-26 | Boston Scientific Scimed, Inc. | Valved embolic protection filter |
US20050004594A1 (en) * | 2003-07-02 | 2005-01-06 | Jeffrey Nool | Devices and methods for aspirating from filters |
US8337519B2 (en) | 2003-07-10 | 2012-12-25 | Boston Scientific Scimed, Inc. | Embolic protection filtering device |
US7662143B2 (en) * | 2003-07-29 | 2010-02-16 | Boston Scientific Scimed, Inc. | Apparatus and method for treating intravascular disease |
US9301829B2 (en) * | 2003-07-30 | 2016-04-05 | Boston Scientific Scimed, Inc. | Embolic protection aspirator |
US7402141B2 (en) * | 2003-08-27 | 2008-07-22 | Heuser Richard R | Catheter guidewire system using concentric wires |
US20050049669A1 (en) | 2003-08-29 | 2005-03-03 | Jones Donald K. | Self-expanding stent and stent delivery system with distal protection |
US20050049670A1 (en) * | 2003-08-29 | 2005-03-03 | Jones Donald K. | Self-expanding stent and stent delivery system for treatment of vascular disease |
US20050049668A1 (en) * | 2003-08-29 | 2005-03-03 | Jones Donald K. | Self-expanding stent and stent delivery system for treatment of vascular stenosis |
US8535344B2 (en) * | 2003-09-12 | 2013-09-17 | Rubicon Medical, Inc. | Methods, systems, and devices for providing embolic protection and removing embolic material |
US7699865B2 (en) | 2003-09-12 | 2010-04-20 | Rubicon Medical, Inc. | Actuating constraining mechanism |
US7205624B2 (en) * | 2003-10-07 | 2007-04-17 | Applied Materials, Inc. | Self-aligned implanted waveguide detector |
US20100174352A1 (en) * | 2003-10-16 | 2010-07-08 | Minvasys, Sa | Catheter system for angioplasty and stenting with embolic protection |
US7892251B1 (en) | 2003-11-12 | 2011-02-22 | Advanced Cardiovascular Systems, Inc. | Component for delivering and locking a medical device to a guide wire |
US7780692B2 (en) * | 2003-12-05 | 2010-08-24 | Onset Medical Corporation | Expandable percutaneous sheath |
US9241735B2 (en) * | 2003-12-05 | 2016-01-26 | Onset Medical Corporation | Expandable percutaneous sheath |
US7651514B2 (en) * | 2003-12-11 | 2010-01-26 | Boston Scientific Scimed, Inc. | Nose rider improvement for filter exchange and methods of use |
US7748389B2 (en) * | 2003-12-23 | 2010-07-06 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US8579962B2 (en) | 2003-12-23 | 2013-11-12 | Sadra Medical, Inc. | Methods and apparatus for performing valvuloplasty |
US8287584B2 (en) * | 2005-11-14 | 2012-10-16 | Sadra Medical, Inc. | Medical implant deployment tool |
US8052749B2 (en) * | 2003-12-23 | 2011-11-08 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US7445631B2 (en) | 2003-12-23 | 2008-11-04 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20050137691A1 (en) * | 2003-12-23 | 2005-06-23 | Sadra Medical | Two piece heart valve and anchor |
US7329279B2 (en) * | 2003-12-23 | 2008-02-12 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US7381219B2 (en) * | 2003-12-23 | 2008-06-03 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
US8182528B2 (en) | 2003-12-23 | 2012-05-22 | Sadra Medical, Inc. | Locking heart valve anchor |
US9526609B2 (en) * | 2003-12-23 | 2016-12-27 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8840663B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US7959666B2 (en) * | 2003-12-23 | 2011-06-14 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
EP2526895B1 (en) * | 2003-12-23 | 2014-01-29 | Sadra Medical, Inc. | Repositionable heart valve |
US7780725B2 (en) * | 2004-06-16 | 2010-08-24 | Sadra Medical, Inc. | Everting heart valve |
US20050137686A1 (en) * | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Externally expandable heart valve anchor and method |
US11278398B2 (en) | 2003-12-23 | 2022-03-22 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US20050137687A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Heart valve anchor and method |
US7824443B2 (en) | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Medical implant delivery and deployment tool |
US8603160B2 (en) | 2003-12-23 | 2013-12-10 | Sadra Medical, Inc. | Method of using a retrievable heart valve anchor with a sheath |
US20120041550A1 (en) | 2003-12-23 | 2012-02-16 | Sadra Medical, Inc. | Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements |
US9005273B2 (en) * | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
US7824442B2 (en) * | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US20050137694A1 (en) | 2003-12-23 | 2005-06-23 | Haug Ulrich R. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20050159773A1 (en) * | 2004-01-20 | 2005-07-21 | Scimed Life Systems, Inc. | Expandable retrieval device with dilator tip |
US20050159772A1 (en) * | 2004-01-20 | 2005-07-21 | Scimed Life Systems, Inc. | Sheath for use with an embolic protection filtering device |
US7704266B2 (en) * | 2004-01-22 | 2010-04-27 | Rex Medical, L.P. | Vein filter |
US8211140B2 (en) | 2004-01-22 | 2012-07-03 | Rex Medical, L.P. | Vein filter |
US8162972B2 (en) | 2004-01-22 | 2012-04-24 | Rex Medical, Lp | Vein filter |
US8062326B2 (en) | 2004-01-22 | 2011-11-22 | Rex Medical, L.P. | Vein filter |
US8500774B2 (en) | 2004-01-22 | 2013-08-06 | Rex Medical, L.P. | Vein filter |
US9510929B2 (en) | 2004-01-22 | 2016-12-06 | Argon Medical Devices, Inc. | Vein filter |
US7976562B2 (en) * | 2004-01-22 | 2011-07-12 | Rex Medical, L.P. | Method of removing a vein filter |
US7338512B2 (en) * | 2004-01-22 | 2008-03-04 | Rex Medical, L.P. | Vein filter |
US20060106447A1 (en) * | 2004-01-26 | 2006-05-18 | Nmt Medical, Inc. | Adjustable stiffness medical system |
WO2005082271A2 (en) | 2004-03-01 | 2005-09-09 | Coloplast A/S | An ostomy appliance |
US8092483B2 (en) * | 2004-03-06 | 2012-01-10 | Medtronic, Inc. | Steerable device having a corewire within a tube and combination with a functional medical component |
US7988705B2 (en) * | 2004-03-06 | 2011-08-02 | Lumen Biomedical, Inc. | Steerable device having a corewire within a tube and combination with a functional medical component |
US8308750B2 (en) * | 2004-03-10 | 2012-11-13 | Boston Scientific Scimed, Inc. | Removable intravascular devices and methods of making and using the same |
US7678129B1 (en) * | 2004-03-19 | 2010-03-16 | Advanced Cardiovascular Systems, Inc. | Locking component for an embolic filter assembly |
US7686825B2 (en) * | 2004-03-25 | 2010-03-30 | Hauser David L | Vascular filter device |
DE102004015641B3 (en) * | 2004-03-31 | 2006-03-09 | Siemens Ag | Device for elimination of complete occlusion with IVUS monitoring |
US20050240215A1 (en) * | 2004-04-21 | 2005-10-27 | Scimed Life Systems, Inc. | Magnetic embolic protection device and method |
US7922759B1 (en) | 2004-04-22 | 2011-04-12 | Cook Medical Technologies Llc | Apparatus and methods for vascular treatment |
JP2005323702A (en) * | 2004-05-13 | 2005-11-24 | Asahi Intecc Co Ltd | Medical treatment instrument |
US8409237B2 (en) * | 2004-05-27 | 2013-04-02 | Medtronic, Inc. | Emboli filter export system |
US8241315B2 (en) | 2004-06-24 | 2012-08-14 | Boston Scientific Scimed, Inc. | Apparatus and method for treating occluded vasculature |
US20060293612A1 (en) * | 2004-06-24 | 2006-12-28 | Boston Scientific Scimed, Inc. | Apparatus and method for treating occluded vasculature |
US7976516B2 (en) * | 2004-06-25 | 2011-07-12 | Lumen Biomedical, Inc. | Medical device having mechanically interlocked segments |
US7794472B2 (en) * | 2004-08-11 | 2010-09-14 | Boston Scientific Scimed, Inc. | Single wire intravascular filter |
US7013899B2 (en) * | 2004-08-13 | 2006-03-21 | Engineered Medical System, Inc. | Perilaryngeal oral airway with multi-lumen esophogeal-obturator |
US20090012429A1 (en) * | 2004-08-25 | 2009-01-08 | Heuser Richard R | Catheter guidewire system using concentric wires |
US8545418B2 (en) | 2004-08-25 | 2013-10-01 | Richard R. Heuser | Systems and methods for ablation of occlusions within blood vessels |
US20060047301A1 (en) * | 2004-09-02 | 2006-03-02 | Ogle Matthew F | Emboli removal system with oxygenated flow |
EP1819391B1 (en) | 2004-09-09 | 2020-02-19 | Onset Medical Corporation | Expandable transluminal sheath |
US20060135962A1 (en) * | 2004-09-09 | 2006-06-22 | Kick George F | Expandable trans-septal sheath |
US7892203B2 (en) | 2004-09-09 | 2011-02-22 | Onset Medical Corporation | Expandable transluminal sheath |
US20060064056A1 (en) * | 2004-09-17 | 2006-03-23 | James Coyle | Guiding catheter assembly for embolic protection by proximal occlusion |
ES2444590T3 (en) * | 2004-09-27 | 2014-02-25 | Rex Medical, L.P. | Venous filter |
WO2006042114A1 (en) * | 2004-10-06 | 2006-04-20 | Cook, Inc. | Emboli capturing device having a coil and method for capturing emboli |
US7621904B2 (en) * | 2004-10-21 | 2009-11-24 | Boston Scientific Scimed, Inc. | Catheter with a pre-shaped distal tip |
US20060095067A1 (en) * | 2004-11-01 | 2006-05-04 | Horng-Ban Lin | Lubricious filter |
US7959645B2 (en) * | 2004-11-03 | 2011-06-14 | Boston Scientific Scimed, Inc. | Retrievable vena cava filter |
WO2006055967A2 (en) * | 2004-11-19 | 2006-05-26 | Lumen Biomedical, Inc. | Extendable device on an aspiration catheter |
US9707071B2 (en) | 2004-11-24 | 2017-07-18 | Contego Medical Llc | Percutaneous transluminal angioplasty device with integral embolic filter |
US8038696B2 (en) * | 2004-12-06 | 2011-10-18 | Boston Scientific Scimed, Inc. | Sheath for use with an embolic protection filter |
CN101076290B (en) | 2004-12-09 | 2011-11-23 | 铸造品股份有限公司 | Aortic valve repair |
US20060129181A1 (en) * | 2004-12-13 | 2006-06-15 | Callol Joseph R | Retrieval device with retractable dilator tip |
US8252016B2 (en) | 2005-01-13 | 2012-08-28 | Azam Anwar | System and method for providing embolic protection |
DE102005003632A1 (en) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Catheter for the transvascular implantation of heart valve prostheses |
US7204464B2 (en) * | 2005-01-21 | 2007-04-17 | Boston Scientific Scimed, Inc. | Medical wire holder |
US7963989B2 (en) * | 2005-01-24 | 2011-06-21 | Technology Advancement Group, Inc. | Implantable prosthetic device for connection to a fluid flow pathway of a patient |
US8480629B2 (en) * | 2005-01-28 | 2013-07-09 | Boston Scientific Scimed, Inc. | Universal utility board for use with medical devices and methods of use |
US20060184194A1 (en) * | 2005-02-15 | 2006-08-17 | Cook Incorporated | Embolic protection device |
US20060190024A1 (en) * | 2005-02-24 | 2006-08-24 | Bei Nianjiong | Recovery catheter apparatus and method |
US20060200168A1 (en) * | 2005-03-03 | 2006-09-07 | Azam Anwar | System and method for providing access in divergent directions in a vascular environment |
US7998164B2 (en) * | 2005-03-11 | 2011-08-16 | Boston Scientific Scimed, Inc. | Intravascular filter with centering member |
US8221446B2 (en) | 2005-03-15 | 2012-07-17 | Cook Medical Technologies | Embolic protection device |
US8945169B2 (en) | 2005-03-15 | 2015-02-03 | Cook Medical Technologies Llc | Embolic protection device |
US20060224175A1 (en) * | 2005-03-29 | 2006-10-05 | Vrba Anthony C | Methods and apparatuses for disposition of a medical device onto an elongate medical device |
US9259305B2 (en) | 2005-03-31 | 2016-02-16 | Abbott Cardiovascular Systems Inc. | Guide wire locking mechanism for rapid exchange and other catheter systems |
US20060229658A1 (en) * | 2005-04-07 | 2006-10-12 | Stivland Timothy M | Embolic protection filter with reduced landing zone |
US7962208B2 (en) | 2005-04-25 | 2011-06-14 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
JP2006304835A (en) * | 2005-04-26 | 2006-11-09 | Nippon Zeon Co Ltd | Basket type medical treatment tool |
US20060259066A1 (en) * | 2005-04-28 | 2006-11-16 | Euteneuer Charles L | Bifurcated artery filter system |
US20060259132A1 (en) * | 2005-05-02 | 2006-11-16 | Cook Incorporated | Vascular stent for embolic protection |
GB2426457A (en) * | 2005-05-26 | 2006-11-29 | Leonid Shturman | Balloon angioplasty device with distal protection capability |
US20060282115A1 (en) * | 2005-06-09 | 2006-12-14 | Abrams Robert M | Thin film vessel occlusion device |
US20070027522A1 (en) * | 2005-06-14 | 2007-02-01 | Chang Jean C | Stent delivery and guidewire systems |
US20070005097A1 (en) * | 2005-06-20 | 2007-01-04 | Renati Richard J | Intravascular filter |
US8109962B2 (en) | 2005-06-20 | 2012-02-07 | Cook Medical Technologies Llc | Retrievable device having a reticulation portion with staggered struts |
US7850708B2 (en) * | 2005-06-20 | 2010-12-14 | Cook Incorporated | Embolic protection device having a reticulated body with staggered struts |
US7771452B2 (en) | 2005-07-12 | 2010-08-10 | Cook Incorporated | Embolic protection device with a filter bag that disengages from a basket |
US7766934B2 (en) * | 2005-07-12 | 2010-08-03 | Cook Incorporated | Embolic protection device with an integral basket and bag |
US20080172066A9 (en) * | 2005-07-29 | 2008-07-17 | Galdonik Jason A | Embolectomy procedures with a device comprising a polymer and devices with polymer matrices and supports |
US8187298B2 (en) * | 2005-08-04 | 2012-05-29 | Cook Medical Technologies Llc | Embolic protection device having inflatable frame |
US7938820B2 (en) * | 2005-08-18 | 2011-05-10 | Lumen Biomedical, Inc. | Thrombectomy catheter |
US8021351B2 (en) * | 2005-08-18 | 2011-09-20 | Medtronic Vascular, Inc. | Tracking aspiration catheter |
US7712606B2 (en) | 2005-09-13 | 2010-05-11 | Sadra Medical, Inc. | Two-part package for medical implant |
US8377092B2 (en) | 2005-09-16 | 2013-02-19 | Cook Medical Technologies Llc | Embolic protection device |
US8632562B2 (en) * | 2005-10-03 | 2014-01-21 | Cook Medical Technologies Llc | Embolic protection device |
US8182508B2 (en) * | 2005-10-04 | 2012-05-22 | Cook Medical Technologies Llc | Embolic protection device |
US20070088382A1 (en) * | 2005-10-13 | 2007-04-19 | Bei Nianjiong J | Embolic protection recovery catheter assembly |
US20070088379A1 (en) * | 2005-10-17 | 2007-04-19 | Jacob Schneiderman | Minimally invasive a AAPT extirpation |
US8252017B2 (en) * | 2005-10-18 | 2012-08-28 | Cook Medical Technologies Llc | Invertible filter for embolic protection |
US20070100414A1 (en) | 2005-11-02 | 2007-05-03 | Cardiomind, Inc. | Indirect-release electrolytic implant delivery systems |
US20070100372A1 (en) * | 2005-11-02 | 2007-05-03 | Cook Incorporated | Embolic protection device having a filter |
US8216269B2 (en) | 2005-11-02 | 2012-07-10 | Cook Medical Technologies Llc | Embolic protection device having reduced profile |
US20070106320A1 (en) * | 2005-11-10 | 2007-05-10 | John Blix | Balloon catheter for distal protection compatability |
US8152831B2 (en) * | 2005-11-17 | 2012-04-10 | Cook Medical Technologies Llc | Foam embolic protection device |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US8172792B2 (en) | 2005-12-27 | 2012-05-08 | Tyco Healthcare Group Lp | Embolic protection systems for bifurcated conduits |
US8062321B2 (en) | 2006-01-25 | 2011-11-22 | Pq Bypass, Inc. | Catheter system for connecting adjacent blood vessels |
US20070185567A1 (en) * | 2006-01-25 | 2007-08-09 | Heuser Richard R | Catheter system with stent device for connecting adjacent blood vessels |
MX2008009863A (en) | 2006-02-01 | 2008-12-16 | Cleveland Clinic Foundation | Inflatable-deflatable passive exercise unit. |
WO2007092820A2 (en) | 2006-02-03 | 2007-08-16 | Lazarus Effect, Inc. | Methods and devices for restoring blood flow within blocked vasculature |
US20070185525A1 (en) * | 2006-02-07 | 2007-08-09 | White Bradley R | Floating on the wire filter wire |
US20070203563A1 (en) * | 2006-02-13 | 2007-08-30 | Stephen Hebert | System for delivering a stent |
EP1988851A2 (en) | 2006-02-14 | 2008-11-12 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US20070225644A1 (en) * | 2006-03-08 | 2007-09-27 | Peter Berger | Embolic removal for orthopedic procedures |
EP2004268A4 (en) * | 2006-03-27 | 2009-12-23 | Tel Hashomer Medical Res Infrastructure & Services Ltd | Intraluminal mass collector |
US20070239198A1 (en) * | 2006-04-03 | 2007-10-11 | Boston Scientific Scimed, Inc. | Filter and wire with distal isolation |
US20070265655A1 (en) * | 2006-05-09 | 2007-11-15 | Boston Scientific Scimed, Inc. | Embolic protection filter with enhanced stability within a vessel |
US8361094B2 (en) | 2006-06-30 | 2013-01-29 | Atheromed, Inc. | Atherectomy devices and methods |
US20090018566A1 (en) | 2006-06-30 | 2009-01-15 | Artheromed, Inc. | Atherectomy devices, systems, and methods |
US7981128B2 (en) | 2006-06-30 | 2011-07-19 | Atheromed, Inc. | Atherectomy devices and methods |
EP2037821B1 (en) | 2006-06-30 | 2022-06-22 | Atheromed, Inc. | Atherectomy devices |
US10076401B2 (en) | 2006-08-29 | 2018-09-18 | Argon Medical Devices, Inc. | Vein filter |
ATE556673T1 (en) | 2006-09-08 | 2012-05-15 | Edwards Lifesciences Corp | INTEGRATED HEART VALVE DELIVERY SYSTEM |
US20080071307A1 (en) * | 2006-09-19 | 2008-03-20 | Cook Incorporated | Apparatus and methods for in situ embolic protection |
BRPI0717540A2 (en) * | 2006-09-28 | 2013-10-22 | Heart Leaflet Technologies Inc | SUPPLY INSTRUMENT FOR THE PERCUTANEOUS SUPPLY OF A PROSTHESIS |
US9107736B2 (en) * | 2006-12-06 | 2015-08-18 | Abbott Cardiovascular Systems Inc. | Highly trackable balloon catheter system and method for collapsing an expanded medical device |
US20080147110A1 (en) * | 2006-12-19 | 2008-06-19 | Lalith Hiran Wijeratne | Embolic protection device with distal tubular member for improved torque response |
US8337518B2 (en) | 2006-12-20 | 2012-12-25 | Onset Medical Corporation | Expandable trans-septal sheath |
US7722568B2 (en) | 2007-01-29 | 2010-05-25 | Onset Medical Corporation | Expandable intra-aortic balloon pump sheath |
US9901434B2 (en) | 2007-02-27 | 2018-02-27 | Cook Medical Technologies Llc | Embolic protection device including a Z-stent waist band |
US20080255654A1 (en) * | 2007-03-22 | 2008-10-16 | Bay Street Medical | System for delivering a stent |
WO2008121888A1 (en) | 2007-03-30 | 2008-10-09 | Onset Medical Corporation | Expandable trans-septal sheath |
US7686783B2 (en) * | 2007-03-30 | 2010-03-30 | Boston Scientific Scimed, Inc. | Perfusion and embolic protection |
US7780630B2 (en) * | 2007-03-30 | 2010-08-24 | Boston Scientific Scimed, Inc. | Perfusion device |
US20080243170A1 (en) * | 2007-03-30 | 2008-10-02 | Boston Scientific Scimed, Inc. | Embolic capturing devices and methods |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US8512352B2 (en) | 2007-04-17 | 2013-08-20 | Lazarus Effect, Inc. | Complex wire formed devices |
US11202646B2 (en) | 2007-04-17 | 2021-12-21 | Covidien Lp | Articulating retrieval devices |
US10064635B2 (en) | 2007-04-17 | 2018-09-04 | Covidien Lp | Articulating retrieval devices |
US10076346B2 (en) | 2007-04-17 | 2018-09-18 | Covidien Lp | Complex wire formed devices |
US8216209B2 (en) | 2007-05-31 | 2012-07-10 | Abbott Cardiovascular Systems Inc. | Method and apparatus for delivering an agent to a kidney |
US20080300667A1 (en) * | 2007-05-31 | 2008-12-04 | Bay Street Medical | System for delivering a stent |
US7867273B2 (en) | 2007-06-27 | 2011-01-11 | Abbott Laboratories | Endoprostheses for peripheral arteries and other body vessels |
US9144508B2 (en) * | 2007-07-19 | 2015-09-29 | Back Bay Medical Inc. | Radially expandable stent |
US20090054922A1 (en) * | 2007-08-23 | 2009-02-26 | Broker Harshal S | Apparatus and Method for the Intravascular Control of Trauma |
US9138307B2 (en) | 2007-09-14 | 2015-09-22 | Cook Medical Technologies Llc | Expandable device for treatment of a stricture in a body vessel |
US8252018B2 (en) * | 2007-09-14 | 2012-08-28 | Cook Medical Technologies Llc | Helical embolic protection device |
US8419748B2 (en) * | 2007-09-14 | 2013-04-16 | Cook Medical Technologies Llc | Helical thrombus removal device |
US9220522B2 (en) * | 2007-10-17 | 2015-12-29 | Covidien Lp | Embolus removal systems with baskets |
US20100256600A1 (en) * | 2009-04-04 | 2010-10-07 | Ferrera David A | Neurovascular otw pta balloon catheter and delivery system |
US8070762B2 (en) | 2007-10-22 | 2011-12-06 | Atheromed Inc. | Atherectomy devices and methods |
EP3459572A1 (en) | 2007-11-14 | 2019-03-27 | Biosensors International Group, Ltd. | Automated coating method |
US8613721B2 (en) * | 2007-11-14 | 2013-12-24 | Medrad, Inc. | Delivery and administration of compositions using interventional catheters |
US8545526B2 (en) | 2007-12-26 | 2013-10-01 | Lazarus Effect, Inc. | Retrieval systems and methods for use thereof |
ES2903231T3 (en) | 2008-02-26 | 2022-03-31 | Jenavalve Tech Inc | Stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
US10159472B2 (en) * | 2008-03-02 | 2018-12-25 | V.V.T. Med Ltd. | Method and device for vein ablation |
US8562559B2 (en) | 2008-05-14 | 2013-10-22 | Onset Medical Corporation | Expandable iliac sheath and method of use |
US9440054B2 (en) | 2008-05-14 | 2016-09-13 | Onset Medical Corporation | Expandable transapical sheath and method of use |
US8728153B2 (en) * | 2008-05-14 | 2014-05-20 | Onset Medical Corporation | Expandable transapical sheath and method of use |
US8206412B2 (en) | 2008-06-23 | 2012-06-26 | Lumen Biomedical, Inc. | Embolic protection during percutaneous heart valve replacement and similar procedures |
US8070694B2 (en) | 2008-07-14 | 2011-12-06 | Medtronic Vascular, Inc. | Fiber based medical devices and aspiration catheters |
US8109985B2 (en) | 2008-07-23 | 2012-02-07 | Boston Scientific Scimed, Inc. | Occlusion crossing device and method |
US8162879B2 (en) | 2008-09-22 | 2012-04-24 | Tyco Healthcare Group Lp | Double balloon catheter and methods for homogeneous drug delivery using the same |
CA2739961A1 (en) | 2008-10-10 | 2010-04-15 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US7951110B2 (en) * | 2008-11-10 | 2011-05-31 | Onset Medical Corporation | Expandable spinal sheath and method of use |
US8460183B2 (en) * | 2008-11-17 | 2013-06-11 | Andrew Mark Weinberg | De-looping tool for an endoscope |
US8444669B2 (en) | 2008-12-15 | 2013-05-21 | Boston Scientific Scimed, Inc. | Embolic filter delivery system and method |
US20100152711A1 (en) * | 2008-12-15 | 2010-06-17 | Boston Scientific Scimed, Inc. | Offset coupling region |
US8388644B2 (en) | 2008-12-29 | 2013-03-05 | Cook Medical Technologies Llc | Embolic protection device and method of use |
US20170202657A1 (en) | 2009-01-16 | 2017-07-20 | Claret Medical, Inc. | Intravascular blood filters and methods of use |
US9326843B2 (en) | 2009-01-16 | 2016-05-03 | Claret Medical, Inc. | Intravascular blood filters and methods of use |
US8372108B2 (en) | 2009-01-16 | 2013-02-12 | Claret Medical, Inc. | Intravascular blood filter |
EP2391303A4 (en) * | 2009-01-29 | 2020-09-09 | Boston Scientific Scimed, Inc. | Illuminated intravascular blood filter |
US8382908B2 (en) | 2009-02-06 | 2013-02-26 | Endoclear, Llc | Methods for cleaning endotracheal tubes |
WO2011126812A1 (en) | 2010-03-29 | 2011-10-13 | Endoclear, Llc | Airway cleaning and visualization |
US8468637B2 (en) | 2009-02-06 | 2013-06-25 | Endoclear Llc | Mechanically-actuated endotracheal tube cleaning device |
US20100211094A1 (en) * | 2009-02-18 | 2010-08-19 | Cook Incorporated | Umbrella distal embolic protection device |
EP2403583B1 (en) | 2009-03-06 | 2016-10-19 | Lazarus Effect, Inc. | Retrieval systems |
US20100274231A1 (en) * | 2009-04-24 | 2010-10-28 | Applied Medical Resources Corporation | Renal flushing catheter |
US20100274277A1 (en) * | 2009-04-27 | 2010-10-28 | Cook Incorporated | Embolic protection device with maximized flow-through |
EP2260898A1 (en) * | 2009-06-10 | 2010-12-15 | Ulrich Schäfer | Guide wire and method for its use |
PL2442860T3 (en) * | 2009-06-15 | 2019-09-30 | Perflow Medical Ltd. | Apparatus for allowing blood flow through an occluded vessel |
US8657870B2 (en) * | 2009-06-26 | 2014-02-25 | Biosensors International Group, Ltd. | Implant delivery apparatus and methods with electrolytic release |
US8974489B2 (en) | 2009-07-27 | 2015-03-10 | Claret Medical, Inc. | Dual endovascular filter and methods of use |
EP2480165B1 (en) | 2009-09-21 | 2017-08-23 | Claret Medical, Inc. | Intravascular blood filters |
US20110106135A1 (en) * | 2009-10-29 | 2011-05-05 | Medtronic Vascular, Inc. | Indwelling Temporary IVC Filter System With Drug Delivery and Aspiration |
US8500775B2 (en) * | 2009-12-02 | 2013-08-06 | Surefire Medical, Inc. | Protection device and method against embolization agent reflux |
US8696698B2 (en) | 2009-12-02 | 2014-04-15 | Surefire Medical, Inc. | Microvalve protection device and method of use for protection against embolization agent reflux |
US9539081B2 (en) | 2009-12-02 | 2017-01-10 | Surefire Medical, Inc. | Method of operating a microvalve protection device |
US8801748B2 (en) | 2010-01-22 | 2014-08-12 | Lazarus Effect, Inc. | Retrieval systems and methods for use thereof |
CN102821704A (en) * | 2010-02-05 | 2012-12-12 | 斯瑞克运营有限公司 | Multimode occlusion and stenosis treatment apparatus and method of use |
US9211396B2 (en) | 2010-02-23 | 2015-12-15 | Covidien Lp | Devices and methods for vascular recanalization |
PL2542293T3 (en) * | 2010-03-04 | 2019-06-28 | Grifols Therapeutics Llc | Therapeutic delivery systems |
US9445714B2 (en) | 2010-03-29 | 2016-09-20 | Endoclear Llc | Endotracheal tube coupling adapters |
EP2558005B1 (en) | 2010-04-13 | 2022-03-30 | MIVI Neuroscience, Inc | Embolectomy devices for treatment of acute ischemic stroke condition |
BR112012029896A2 (en) | 2010-05-25 | 2017-06-20 | Jenavalve Tech Inc | prosthetic heart valve for stent graft and stent graft |
WO2012009675A2 (en) | 2010-07-15 | 2012-01-19 | Lazarus Effect, Inc. | Retrieval systems and methods for use thereof |
EP4119107A3 (en) | 2010-09-10 | 2023-02-15 | Boston Scientific Limited | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
US9770319B2 (en) | 2010-12-01 | 2017-09-26 | Surefire Medical, Inc. | Closed tip dynamic microvalve protection device |
US10123865B2 (en) | 2010-12-16 | 2018-11-13 | BiO2 Medical, Inc. | Vascular filter assembly having low profile sheath |
CA3035048C (en) | 2010-12-23 | 2021-05-04 | Mark Deem | System for mitral valve repair and replacement |
US9259306B2 (en) | 2010-12-30 | 2016-02-16 | Claret Medical, Inc. | Aortic embolic protection device |
US8948848B2 (en) | 2011-01-07 | 2015-02-03 | Innovative Cardiovascular Solutions, Llc | Angiography catheter |
US8821478B2 (en) | 2011-03-04 | 2014-09-02 | Boston Scientific Scimed, Inc. | Catheter with variable stiffness |
WO2012127309A1 (en) | 2011-03-21 | 2012-09-27 | Ontorfano Matteo | Disk-based valve apparatus and method for the treatment of valve dysfunction |
EP2520251A1 (en) | 2011-05-05 | 2012-11-07 | Symetis SA | Method and Apparatus for Compressing Stent-Valves |
EP3398539B1 (en) | 2011-05-23 | 2020-08-26 | Covidien LP | Retrieval systems |
US8696731B2 (en) | 2011-06-10 | 2014-04-15 | DePuy Synthes Products, LLC | Lock/floating marker band on pusher wire for self-expanding stents or medical devices |
AU2012272855C1 (en) | 2011-06-21 | 2018-04-05 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
WO2013009975A1 (en) | 2011-07-12 | 2013-01-17 | Boston Scientific Scimed, Inc. | Coupling system for medical devices |
JP2014521462A (en) | 2011-08-05 | 2014-08-28 | シルク・ロード・メディカル・インコーポレイテッド | Method and system for treating acute ischemic stroke |
US9089668B2 (en) | 2011-09-28 | 2015-07-28 | Surefire Medical, Inc. | Flow directional infusion device |
US11202704B2 (en) | 2011-10-19 | 2021-12-21 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US10016271B2 (en) | 2011-10-19 | 2018-07-10 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9763780B2 (en) | 2011-10-19 | 2017-09-19 | Twelve, Inc. | Devices, systems and methods for heart valve replacement |
US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
EP2750630B1 (en) | 2011-10-19 | 2021-06-30 | Twelve, Inc. | Device for heart valve replacement |
US9655722B2 (en) | 2011-10-19 | 2017-05-23 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9131926B2 (en) | 2011-11-10 | 2015-09-15 | Boston Scientific Scimed, Inc. | Direct connect flush system |
US8940014B2 (en) | 2011-11-15 | 2015-01-27 | Boston Scientific Scimed, Inc. | Bond between components of a medical device |
US8951243B2 (en) | 2011-12-03 | 2015-02-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US9277993B2 (en) | 2011-12-20 | 2016-03-08 | Boston Scientific Scimed, Inc. | Medical device delivery systems |
US9510945B2 (en) | 2011-12-20 | 2016-12-06 | Boston Scientific Scimed Inc. | Medical device handle |
EP2805515B1 (en) | 2012-01-17 | 2022-10-05 | Lumen Biomedical, Inc. | Aortic arch filtration system for carotid artery protection |
US8663209B2 (en) | 2012-01-24 | 2014-03-04 | William Harrison Zurn | Vessel clearing apparatus, devices and methods |
US10172708B2 (en) | 2012-01-25 | 2019-01-08 | Boston Scientific Scimed, Inc. | Valve assembly with a bioabsorbable gasket and a replaceable valve implant |
US9089341B2 (en) | 2012-02-28 | 2015-07-28 | Surefire Medical, Inc. | Renal nerve neuromodulation device |
US9579198B2 (en) | 2012-03-01 | 2017-02-28 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
US9883941B2 (en) | 2012-06-19 | 2018-02-06 | Boston Scientific Scimed, Inc. | Replacement heart valve |
US9445828B2 (en) * | 2012-07-05 | 2016-09-20 | Cognition Medical Corp. | Methods, devices, and systems for postconditioning with clot removal |
US11311365B2 (en) | 2012-07-06 | 2022-04-26 | Michael Zhadkevich | Catheter for prevention of stroke and method of use |
US11013515B2 (en) | 2012-07-06 | 2021-05-25 | Michael Zhadkevich | Occluding catheter with an optional common inflation and guideware channel and method of use |
US9913967B2 (en) | 2012-07-06 | 2018-03-13 | Michael Zhadkevich | Occluding catheter and dynamic method for prevention of stroke |
US10537308B2 (en) * | 2012-07-06 | 2020-01-21 | Michael Zhadkevich | Catheter for prevention of stroke and method of use |
US9498225B2 (en) | 2012-07-06 | 2016-11-22 | Michael Zhadkevich | Occluding catheter and method for prevention of stroke |
US9597084B2 (en) | 2012-07-17 | 2017-03-21 | Michael Zhadkevich | Carotid artery occluding apparatus with first and second occluding balloons |
US11160957B2 (en) | 2012-07-17 | 2021-11-02 | Michael Zhadkevich | Carotid artery occluding apparatus with first, second and third occluding balloons |
US9833207B2 (en) | 2012-08-08 | 2017-12-05 | William Harrison Zurn | Analysis and clearing module, system and method |
US20150238207A1 (en) | 2012-09-24 | 2015-08-27 | Inceptus Medical LLC | Device and method for treating vascular occlusion |
US9456834B2 (en) | 2012-10-31 | 2016-10-04 | Covidien Lp | Thrombectomy device with distal protection |
US8784434B2 (en) | 2012-11-20 | 2014-07-22 | Inceptus Medical, Inc. | Methods and apparatus for treating embolism |
US10004863B2 (en) | 2012-12-04 | 2018-06-26 | Endoclear Llc | Closed suction cleaning devices, systems and methods |
WO2014097300A1 (en) | 2012-12-20 | 2014-06-26 | Shlomo Ben-Haim | Multi point treatment probes and methods of using thereof |
US9962533B2 (en) | 2013-02-14 | 2018-05-08 | William Harrison Zurn | Module for treatment of medical conditions; system for making module and methods of making module |
US8715314B1 (en) | 2013-03-15 | 2014-05-06 | Insera Therapeutics, Inc. | Vascular treatment measurement methods |
CN105228688B (en) | 2013-03-15 | 2019-02-19 | 伊瑟拉医疗公司 | Vascular treatment device and method |
US8679150B1 (en) | 2013-03-15 | 2014-03-25 | Insera Therapeutics, Inc. | Shape-set textile structure based mechanical thrombectomy methods |
US9986967B2 (en) * | 2013-03-15 | 2018-06-05 | Volcano Corporation | Distal protection systems and methods with pressure and ultrasound features |
US8690907B1 (en) | 2013-03-15 | 2014-04-08 | Insera Therapeutics, Inc. | Vascular treatment methods |
CN108294846A (en) | 2013-05-20 | 2018-07-20 | 托尔福公司 | Implantable cardiac valve device, mitral valve repair device and related system and method |
US10231751B2 (en) | 2013-05-29 | 2019-03-19 | Thomas A. Sos | Thrombus removal and intravascular distal embolic protection device |
EP3003175B1 (en) | 2013-05-29 | 2020-08-26 | Sos, Thomas, A. | Thrombus removal and intravascular distal embolic protection device |
US9439664B2 (en) * | 2013-05-29 | 2016-09-13 | Thomas A. Sos | Thrombus removal and intravascular distal embolic protection device |
US8870948B1 (en) | 2013-07-17 | 2014-10-28 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US9402708B2 (en) | 2013-07-25 | 2016-08-02 | Covidien Lp | Vascular devices and methods with distal protection |
EP3027126B1 (en) | 2013-07-31 | 2019-10-23 | Atheromed, Inc. | Atherectomy devices |
WO2015028209A1 (en) | 2013-08-30 | 2015-03-05 | Jenavalve Technology Gmbh | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
CN103566459A (en) * | 2013-10-09 | 2014-02-12 | 周少飞 | Anti-jamming balloon catheter |
WO2015061365A1 (en) | 2013-10-21 | 2015-04-30 | Inceptus Medical, Llc | Methods and apparatus for treating embolism |
US9788944B2 (en) * | 2013-10-21 | 2017-10-17 | St. Jude Medical, Cardiology Division, Inc. | Transcatheter valve implantation access sheaths |
US9265512B2 (en) | 2013-12-23 | 2016-02-23 | Silk Road Medical, Inc. | Transcarotid neurovascular catheter |
US20150202037A1 (en) * | 2014-01-23 | 2015-07-23 | Gregory Sullivan | Vascular Filter for Protection During Surgery |
US9820761B2 (en) | 2014-03-21 | 2017-11-21 | Route 92 Medical, Inc. | Rapid aspiration thrombectomy system and method |
US9968740B2 (en) | 2014-03-25 | 2018-05-15 | Surefire Medical, Inc. | Closed tip dynamic microvalve protection device |
US9889031B1 (en) | 2014-03-25 | 2018-02-13 | Surefire Medical, Inc. | Method of gastric artery embolization |
ES2732752T3 (en) | 2014-04-30 | 2019-11-25 | Cerus Endovascular Ltd | Occlusion device |
WO2015187583A1 (en) | 2014-06-03 | 2015-12-10 | Endoclear Llc | Cleaning devices, systems and methods |
US9526864B2 (en) | 2014-06-09 | 2016-12-27 | Inceptus Medical, Llc | Retraction and aspiration device for treating embolism and associated systems and methods |
WO2016067646A1 (en) * | 2014-10-27 | 2016-05-06 | テルモ株式会社 | Medical device |
US9901445B2 (en) | 2014-11-21 | 2018-02-27 | Boston Scientific Scimed, Inc. | Valve locking mechanism |
US9492273B2 (en) | 2014-12-09 | 2016-11-15 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US10449043B2 (en) | 2015-01-16 | 2019-10-22 | Boston Scientific Scimed, Inc. | Displacement based lock and release mechanism |
CA2974532C (en) | 2015-01-23 | 2023-08-29 | Contego Medical Llc | Interventional device having an integrated embolic filter and associated methods |
US9861477B2 (en) | 2015-01-26 | 2018-01-09 | Boston Scientific Scimed Inc. | Prosthetic heart valve square leaflet-leaflet stitch |
US9788942B2 (en) | 2015-02-03 | 2017-10-17 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US10201417B2 (en) | 2015-02-03 | 2019-02-12 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
AU2016215229B2 (en) | 2015-02-04 | 2020-05-07 | Route 92 Medical, Inc. | Rapid aspiration thrombectomy system and method |
US11065019B1 (en) | 2015-02-04 | 2021-07-20 | Route 92 Medical, Inc. | Aspiration catheter systems and methods of use |
US10426497B2 (en) | 2015-07-24 | 2019-10-01 | Route 92 Medical, Inc. | Anchoring delivery system and methods |
EP3256200A1 (en) | 2015-02-11 | 2017-12-20 | Covidien LP | Expandable tip medical devices and methods |
US10426617B2 (en) | 2015-03-06 | 2019-10-01 | Boston Scientific Scimed, Inc. | Low profile valve locking mechanism and commissure assembly |
US10285809B2 (en) | 2015-03-06 | 2019-05-14 | Boston Scientific Scimed Inc. | TAVI anchoring assist device |
US10080652B2 (en) | 2015-03-13 | 2018-09-25 | Boston Scientific Scimed, Inc. | Prosthetic heart valve having an improved tubular seal |
US20160287839A1 (en) | 2015-03-31 | 2016-10-06 | Surefire Medical, Inc. | Apparatus and Method for Infusing an Immunotherapy Agent to a Solid Tumor for Treatment |
US9566144B2 (en) | 2015-04-22 | 2017-02-14 | Claret Medical, Inc. | Vascular filters, deflectors, and methods |
US10709555B2 (en) | 2015-05-01 | 2020-07-14 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
WO2018136959A1 (en) | 2017-01-23 | 2018-07-26 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
EP3294220B1 (en) | 2015-05-14 | 2023-12-06 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
AU2016262564B2 (en) | 2015-05-14 | 2020-11-05 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
ES2820308T3 (en) | 2015-06-30 | 2021-04-20 | Cosette Lee & Harrison Llc | Endovascular catheter with multiple capacities |
US10335277B2 (en) | 2015-07-02 | 2019-07-02 | Boston Scientific Scimed Inc. | Adjustable nosecone |
US10195392B2 (en) | 2015-07-02 | 2019-02-05 | Boston Scientific Scimed, Inc. | Clip-on catheter |
US10179041B2 (en) | 2015-08-12 | 2019-01-15 | Boston Scientific Scimed Icn. | Pinless release mechanism |
US10136991B2 (en) | 2015-08-12 | 2018-11-27 | Boston Scientific Scimed Inc. | Replacement heart valve implant |
CN107920895B (en) | 2015-08-21 | 2020-06-26 | 托尔福公司 | Implantable heart valve devices, mitral valve repair devices, and associated systems and methods |
US10463386B2 (en) | 2015-09-01 | 2019-11-05 | Mivi Neuroscience, Inc. | Thrombectomy devices and treatment of acute ischemic stroke with thrombus engagement |
US10779940B2 (en) | 2015-09-03 | 2020-09-22 | Boston Scientific Scimed, Inc. | Medical device handle |
JP7253376B2 (en) | 2015-10-23 | 2023-04-06 | イナリ メディカル, インコーポレイテッド | Endovascular treatment of vascular occlusion and related devices, systems and methods |
US10342571B2 (en) | 2015-10-23 | 2019-07-09 | Inari Medical, Inc. | Intravascular treatment of vascular occlusion and associated devices, systems, and methods |
US9700332B2 (en) | 2015-10-23 | 2017-07-11 | Inari Medical, Inc. | Intravascular treatment of vascular occlusion and associated devices, systems, and methods |
US10716915B2 (en) * | 2015-11-23 | 2020-07-21 | Mivi Neuroscience, Inc. | Catheter systems for applying effective suction in remote vessels and thrombectomy procedures facilitated by catheter systems |
EP3386402B1 (en) | 2015-12-07 | 2022-02-23 | Cerus Endovascular Limited | Occlusion device |
US10531882B2 (en) * | 2016-01-04 | 2020-01-14 | Alcyone Lifesciences, Inc. | Methods and devices for treating stroke |
US10342660B2 (en) | 2016-02-02 | 2019-07-09 | Boston Scientific Inc. | Tensioned sheathing aids |
EP3416568A4 (en) | 2016-02-16 | 2019-10-16 | Insera Therapeutics, Inc. | Aspiration devices and anchored flow diverting devices |
EP3782576A1 (en) | 2016-03-11 | 2021-02-24 | Cerus Endovascular Limited | Occlusion device |
CN109069272A (en) | 2016-04-29 | 2018-12-21 | 美敦力瓦斯科尔勒公司 | Prosthetic heart valve equipment and associated system and method with the anchor log with tether |
EP3451940B1 (en) * | 2016-05-03 | 2024-01-03 | Access Flow Systems, LLC | Vascular access devices and systems |
US10245136B2 (en) | 2016-05-13 | 2019-04-02 | Boston Scientific Scimed Inc. | Containment vessel with implant sheathing guide |
CN109475419B (en) | 2016-05-13 | 2021-11-09 | 耶拿阀门科技股份有限公司 | Heart valve prosthesis delivery systems and methods for delivering heart valve prostheses through guide sheaths and loading systems |
US10583005B2 (en) | 2016-05-13 | 2020-03-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US10201416B2 (en) | 2016-05-16 | 2019-02-12 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
KR101698294B1 (en) * | 2016-05-17 | 2017-02-01 | 주식회사 인성메디칼 | Port for Delivering Medicine |
WO2017218877A1 (en) | 2016-06-17 | 2017-12-21 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
JP7177061B2 (en) | 2016-09-01 | 2022-11-22 | マイクロベンション インコーポレイテッド | Temporary aortic isolation device |
US11389169B2 (en) | 2016-09-01 | 2022-07-19 | Microvention, Inc. | Temporary aortic occlusion device |
US10314684B2 (en) * | 2016-09-07 | 2019-06-11 | Daniel Ezra Walzman | Simultaneous rotating separator, irrigator microcatheter for thrombectomy |
US10299824B2 (en) * | 2016-09-07 | 2019-05-28 | Daniel Ezra Walzman | Rotating separator, irrigator microcatheter for thrombectomy |
US11439492B2 (en) | 2016-09-07 | 2022-09-13 | Daniel Ezra Walzman | Lasso filter tipped microcatheter for simultaneous rotating separator, irrigator for thrombectomy and method for use |
US11259820B2 (en) | 2016-09-07 | 2022-03-01 | Daniel Ezra Walzman | Methods and devices to ameliorate vascular obstruction |
US11877752B2 (en) * | 2016-09-07 | 2024-01-23 | Daniel Ezra Walzman | Filterless aspiration, irrigating, macerating, rotating microcatheter and method of use |
US11400263B1 (en) | 2016-09-19 | 2022-08-02 | Trisalus Life Sciences, Inc. | System and method for selective pressure-controlled therapeutic delivery |
US10780250B1 (en) | 2016-09-19 | 2020-09-22 | Surefire Medical, Inc. | System and method for selective pressure-controlled therapeutic delivery |
JP6785106B2 (en) | 2016-09-27 | 2020-11-18 | テルモ株式会社 | Medical system |
EP3522798A4 (en) | 2016-10-06 | 2020-05-13 | Mivi Neuroscience, Inc. | Hydraulic displacement and removal of thrombus clots, and catheters for performing hydraulic displacement |
CN116421266A (en) | 2016-10-24 | 2023-07-14 | 伊纳里医疗有限公司 | Devices and methods for treating vascular occlusion |
CA3046006A1 (en) * | 2016-12-08 | 2018-06-14 | Michael Calhoun | Methods and devices for treating an eye using a filter |
CN114984407A (en) | 2017-01-10 | 2022-09-02 | 92号医疗公司 | System, catheter and catheter advancement device for performing medical procedures in intracranial vessels |
EP4209196A1 (en) | 2017-01-23 | 2023-07-12 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
CN110392557A (en) | 2017-01-27 | 2019-10-29 | 耶拿阀门科技股份有限公司 | Heart valve simulation |
CN110831545B (en) | 2017-02-22 | 2022-06-07 | 波士顿科学国际有限公司 | System and method for protecting cerebral blood vessels |
US10588636B2 (en) | 2017-03-20 | 2020-03-17 | Surefire Medical, Inc. | Dynamic reconfigurable microvalve protection device |
US10433961B2 (en) | 2017-04-18 | 2019-10-08 | Twelve, Inc. | Delivery systems with tethers for prosthetic heart valve devices and associated methods |
US10702378B2 (en) | 2017-04-18 | 2020-07-07 | Twelve, Inc. | Prosthetic heart valve device and associated systems and methods |
US10575950B2 (en) | 2017-04-18 | 2020-03-03 | Twelve, Inc. | Hydraulic systems for delivering prosthetic heart valve devices and associated methods |
US10792151B2 (en) | 2017-05-11 | 2020-10-06 | Twelve, Inc. | Delivery systems for delivering prosthetic heart valve devices and associated methods |
US11129630B2 (en) | 2017-05-12 | 2021-09-28 | Covidien Lp | Retrieval of material from vessel lumens |
US11298145B2 (en) | 2017-05-12 | 2022-04-12 | Covidien Lp | Retrieval of material from vessel lumens |
US11191555B2 (en) | 2017-05-12 | 2021-12-07 | Covidien Lp | Retrieval of material from vessel lumens |
US10722257B2 (en) | 2017-05-12 | 2020-07-28 | Covidien Lp | Retrieval of material from vessel lumens |
US10709464B2 (en) | 2017-05-12 | 2020-07-14 | Covidien Lp | Retrieval of material from vessel lumens |
US10478535B2 (en) | 2017-05-24 | 2019-11-19 | Mivi Neuroscience, Inc. | Suction catheter systems for applying effective aspiration in remote vessels, especially cerebral arteries |
US11234723B2 (en) | 2017-12-20 | 2022-02-01 | Mivi Neuroscience, Inc. | Suction catheter systems for applying effective aspiration in remote vessels, especially cerebral arteries |
US10646338B2 (en) | 2017-06-02 | 2020-05-12 | Twelve, Inc. | Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods |
US10709591B2 (en) | 2017-06-06 | 2020-07-14 | Twelve, Inc. | Crimping device and method for loading stents and prosthetic heart valves |
EP3634311A1 (en) | 2017-06-08 | 2020-04-15 | Boston Scientific Scimed, Inc. | Heart valve implant commissure support structure |
US10945746B2 (en) | 2017-06-12 | 2021-03-16 | Covidien Lp | Tools for sheathing treatment devices and associated systems and methods |
US10478322B2 (en) | 2017-06-19 | 2019-11-19 | Covidien Lp | Retractor device for transforming a retrieval device from a deployed position to a delivery position |
US10575864B2 (en) | 2017-06-22 | 2020-03-03 | Covidien Lp | Securing element for resheathing an intravascular device and associated systems and methods |
US10786352B2 (en) | 2017-07-06 | 2020-09-29 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US10729541B2 (en) | 2017-07-06 | 2020-08-04 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
EP3661458A1 (en) | 2017-08-01 | 2020-06-10 | Boston Scientific Scimed, Inc. | Medical implant locking mechanism |
CN111225633B (en) | 2017-08-16 | 2022-05-31 | 波士顿科学国际有限公司 | Replacement heart valve coaptation assembly |
US11812971B2 (en) | 2017-08-21 | 2023-11-14 | Cerus Endovascular Limited | Occlusion device |
EP3678731A4 (en) | 2017-09-06 | 2021-06-09 | Inari Medical, Inc. | Hemostasis valves and methods of use |
AU2021362245A1 (en) | 2017-10-16 | 2023-05-25 | Retriever Medical, Inc. | Clot removal methods and devices with multiple independently controllable elements |
US20220104839A1 (en) | 2017-10-16 | 2022-04-07 | Retriever Medical, Inc. | Clot Removal Methods and Devices with Multiple Independently Controllable Elements |
US20190110804A1 (en) | 2017-10-16 | 2019-04-18 | Michael Bruce Horowitz | Catheter based retrieval device with proximal body having axial freedom of movement |
EP3700464B1 (en) | 2017-10-27 | 2024-02-14 | Boston Scientific Scimed, Inc. | Systems for protecting the cerebral vasculature |
EP3727192B1 (en) | 2017-12-19 | 2023-03-08 | Boston Scientific Scimed, Inc. | System for protecting the cerebral vasculature |
WO2019144069A2 (en) | 2018-01-19 | 2019-07-25 | Boston Scientific Scimed, Inc. | Inductance mode deployment sensors for transcatheter valve system |
JP7047106B2 (en) | 2018-01-19 | 2022-04-04 | ボストン サイエンティフィック サイムド,インコーポレイテッド | Medical device delivery system with feedback loop |
US11154314B2 (en) | 2018-01-26 | 2021-10-26 | Inari Medical, Inc. | Single insertion delivery system for treating embolism and associated systems and methods |
EP3749252A1 (en) | 2018-02-07 | 2020-12-16 | Boston Scientific Scimed, Inc. | Medical device delivery system with alignment feature |
WO2019165394A1 (en) | 2018-02-26 | 2019-08-29 | Boston Scientific Scimed, Inc. | Embedded radiopaque marker in adaptive seal |
JP7401446B2 (en) | 2018-03-07 | 2023-12-19 | イノベイティブ カーディオバスキュラー ソリューションズ, エルエルシー | Embolic protection device |
EP3784168B1 (en) | 2018-04-26 | 2024-03-20 | Boston Scientific Scimed, Inc. | Systems for protecting the cerebral vasculature |
CN112423704A (en) | 2018-05-09 | 2021-02-26 | 波士顿科学国际有限公司 | Foot entering embolism filtering sleeve |
EP3793478A1 (en) | 2018-05-15 | 2021-03-24 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
EP3793660A2 (en) | 2018-05-17 | 2021-03-24 | Route 92 Medical, Inc. | Aspiration catheter systems and methods of use |
EP3813727B1 (en) | 2018-05-30 | 2023-08-30 | Elum Technologies, Inc. | Integrated thrombectomy and filter device |
US11241310B2 (en) | 2018-06-13 | 2022-02-08 | Boston Scientific Scimed, Inc. | Replacement heart valve delivery device |
CN112638240A (en) | 2018-07-20 | 2021-04-09 | 艾露姆技术股份有限公司 | Neurovascular distal access support catheter, aspiration catheter or device shaft |
US11850398B2 (en) | 2018-08-01 | 2023-12-26 | Trisalus Life Sciences, Inc. | Systems and methods for pressure-facilitated therapeutic agent delivery |
WO2020036809A1 (en) | 2018-08-13 | 2020-02-20 | Inari Medical, Inc. | System for treating embolism and associated devices and methods |
CN112930152A (en) | 2018-08-21 | 2021-06-08 | 波士顿科学国际有限公司 | System and method for protecting cerebral blood vessels |
US20200069921A1 (en) * | 2018-08-30 | 2020-03-05 | Q3 Medical Devices Limited | Device for occlusion isolation and removal |
US11253287B2 (en) | 2018-10-04 | 2022-02-22 | Neuravi Limited | Retrograde blood flow occlusion flushing device |
US11338117B2 (en) | 2018-10-08 | 2022-05-24 | Trisalus Life Sciences, Inc. | Implantable dual pathway therapeutic agent delivery port |
US11272945B2 (en) | 2018-10-10 | 2022-03-15 | Innova Vascular, Inc. | Device for removing an embolus |
US11241312B2 (en) | 2018-12-10 | 2022-02-08 | Boston Scientific Scimed, Inc. | Medical device delivery system including a resistance member |
US11963864B2 (en) * | 2019-01-11 | 2024-04-23 | Varun Shetty | Method and system for reducing pulmonary flow |
JP2020151465A (en) * | 2019-03-12 | 2020-09-24 | テルモ株式会社 | Treatment method, separation method, and filter assembly |
US11819227B2 (en) | 2019-03-12 | 2023-11-21 | Terumo Kabushiki Kaisha | Treatment method, separation method, and filter assembly |
GB201905551D0 (en) * | 2019-04-18 | 2019-06-05 | Tel Hashomer Medical Res Infrastructure & Services Ltd | Embolic protection device |
US11439504B2 (en) | 2019-05-10 | 2022-09-13 | Boston Scientific Scimed, Inc. | Replacement heart valve with improved cusp washout and reduced loading |
US11707351B2 (en) | 2019-08-19 | 2023-07-25 | Encompass Technologies, Inc. | Embolic protection and access system |
AU2020368528A1 (en) | 2019-10-16 | 2022-04-21 | Inari Medical, Inc. | Systems, devices, and methods for treating vascular occlusions |
US11925745B1 (en) * | 2019-11-27 | 2024-03-12 | Clearflow, Inc. | Clearance system for medical tubes such as surgical drains |
US11617865B2 (en) | 2020-01-24 | 2023-04-04 | Mivi Neuroscience, Inc. | Suction catheter systems with designs allowing rapid clearing of clots |
US11406404B2 (en) * | 2020-02-20 | 2022-08-09 | Cerus Endovascular Limited | Clot removal distal protection methods |
WO2022004850A1 (en) * | 2020-07-03 | 2022-01-06 | 和也 正林 | Distal stabilizer for delivery of catheter within biological lumen, system for delivering treatment device, and treatment device |
WO2022077781A1 (en) * | 2020-10-13 | 2022-04-21 | 上海腾复医疗科技有限公司 | Drug injection stent and drug injection thrombolytic system comprising same |
US11925544B2 (en) | 2020-10-13 | 2024-03-12 | Shanghai Tendfo Medical Technologies Co. Ltd. | Pulmonary artery stent |
US11304723B1 (en) | 2020-12-17 | 2022-04-19 | Avantec Vascular Corporation | Atherectomy devices that are self-driving with controlled deflection |
CN113143378B (en) * | 2021-04-15 | 2023-03-17 | 湖南思脉医疗器械有限公司 | Sliding sheath tube capable of plugging artery and vein |
CN113749731B (en) * | 2021-09-22 | 2024-04-05 | 四川省医学科学院·四川省人民医院 | Thrombus suction device for vascular surgery |
Family Cites Families (225)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3472230A (en) | 1966-12-19 | 1969-10-14 | Fogarty T J | Umbrella catheter |
US3592186A (en) | 1969-01-28 | 1971-07-13 | Claude Oster | Cytologic scraper |
US3683904A (en) | 1970-10-05 | 1972-08-15 | Howard B Forster | Pessaries |
US3889657A (en) | 1974-02-12 | 1975-06-17 | Gomco Surgical Mfg Co | Uterine aspirating curette |
US3952747A (en) | 1974-03-28 | 1976-04-27 | Kimmell Jr Garman O | Filter and filter insertion instrument |
US3996938A (en) | 1975-07-10 | 1976-12-14 | Clark Iii William T | Expanding mesh catheter |
US4046150A (en) | 1975-07-17 | 1977-09-06 | American Hospital Supply Corporation | Medical instrument for locating and removing occlusive objects |
SU764684A1 (en) | 1978-01-31 | 1980-09-25 | Челябинский государственный медицинский институт | Trap filter |
DE2821048C2 (en) | 1978-05-13 | 1980-07-17 | Willy Ruesch Gmbh & Co Kg, 7053 Kernen | Medical instrument |
US4425908A (en) | 1981-10-22 | 1984-01-17 | Beth Israel Hospital | Blood clot filter |
US4447227A (en) | 1982-06-09 | 1984-05-08 | Endoscopy Surgical Systems, Inc. | Multi-purpose medical devices |
US4643184A (en) | 1982-09-29 | 1987-02-17 | Mobin Uddin Kazi | Embolus trap |
US5190546A (en) | 1983-10-14 | 1993-03-02 | Raychem Corporation | Medical devices incorporating SIM alloy elements |
US5104399A (en) | 1986-12-10 | 1992-04-14 | Endovascular Technologies, Inc. | Artificial graft and implantation method |
US4631052A (en) | 1984-01-03 | 1986-12-23 | Intravascular Surgical Instruments, Inc. | Method and apparatus for surgically removing remote deposits |
US4590938A (en) | 1984-05-04 | 1986-05-27 | Segura Joseph W | Medical retriever device |
DE3417738C2 (en) | 1984-05-12 | 1986-10-02 | Ing. Walter Hengst GmbH & Co KG, 4400 Münster | Blood filter that can be used in veins |
US4957482A (en) | 1988-12-19 | 1990-09-18 | Surgical Systems & Instruments, Inc. | Atherectomy device with a positive pump means |
US4842579B1 (en) | 1984-05-14 | 1995-10-31 | Surgical Systems & Instr Inc | Atherectomy device |
US5007896A (en) | 1988-12-19 | 1991-04-16 | Surgical Systems & Instruments, Inc. | Rotary-catheter for atherectomy |
US5135531A (en) | 1984-05-14 | 1992-08-04 | Surgical Systems & Instruments, Inc. | Guided atherectomy system |
DK151404C (en) | 1984-05-23 | 1988-07-18 | Cook Europ Aps William | FULLY FILTER FOR IMPLANTATION IN A PATIENT'S BLOOD |
US4979951A (en) | 1984-05-30 | 1990-12-25 | Simpson John B | Atherectomy device and method |
US4926858A (en) | 1984-05-30 | 1990-05-22 | Devices For Vascular Intervention, Inc. | Atherectomy device for severe occlusions |
US4580568A (en) | 1984-10-01 | 1986-04-08 | Cook, Incorporated | Percutaneous endovascular stent and method for insertion thereof |
US4790813A (en) | 1984-12-17 | 1988-12-13 | Intravascular Surgical Instruments, Inc. | Method and apparatus for surgically removing remote deposits |
US4807626A (en) | 1985-02-14 | 1989-02-28 | Mcgirr Douglas B | Stone extractor and method |
IT8535720V0 (en) | 1985-03-27 | 1985-03-27 | Ital Idee Srl | AIR INTAKE FILTER CLOGGING INDICATOR, IN PARTICULAR FOR MOTOR VEHICLE ENGINES |
FR2580504B1 (en) | 1985-04-22 | 1987-07-10 | Pieronne Alain | FILTER FOR THE PARTIAL AND AT LEAST PROVISIONAL INTERRUPTION OF A VEIN AND CATHETER CARRYING THE FILTER |
US4706671A (en) | 1985-05-02 | 1987-11-17 | Weinrib Harry P | Catheter with coiled tip |
JPS62128976A (en) * | 1985-08-14 | 1987-06-11 | ブ−フタル・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフトウング | Large format ceramic tile |
US4662885A (en) | 1985-09-03 | 1987-05-05 | Becton, Dickinson And Company | Percutaneously deliverable intravascular filter prosthesis |
US4705517A (en) | 1985-09-03 | 1987-11-10 | Becton, Dickinson And Company | Percutaneously deliverable intravascular occlusion prosthesis |
US4650466A (en) | 1985-11-01 | 1987-03-17 | Angiobrade Partners | Angioplasty device |
US4733665C2 (en) | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
US4790812A (en) * | 1985-11-15 | 1988-12-13 | Hawkins Jr Irvin F | Apparatus and method for removing a target object from a body passsageway |
US4921483A (en) * | 1985-12-19 | 1990-05-01 | Leocor, Inc. | Angioplasty catheter |
US4665918A (en) * | 1986-01-06 | 1987-05-19 | Garza Gilbert A | Prosthesis system and method |
USRE33569E (en) | 1986-02-28 | 1991-04-09 | Devices For Vascular Intervention, Inc. | Single lumen atherectomy catheter device |
US4794931A (en) | 1986-02-28 | 1989-01-03 | Cardiovascular Imaging Systems, Inc. | Catheter apparatus, system and method for intravascular two-dimensional ultrasonography |
US4728319A (en) | 1986-03-20 | 1988-03-01 | Helmut Masch | Intravascular catheter |
US4723549A (en) | 1986-09-18 | 1988-02-09 | Wholey Mark H | Method and apparatus for dilating blood vessels |
JPS63158064A (en) | 1986-12-23 | 1988-07-01 | テルモ株式会社 | Blood vessel dilating catheter |
US4832028A (en) * | 1987-02-27 | 1989-05-23 | Patel Piyush V | Catheter assembly and method of performing percutaneous transluminal coronary angioplasty |
US5041126A (en) | 1987-03-13 | 1991-08-20 | Cook Incorporated | Endovascular stent and delivery system |
US4800882A (en) | 1987-03-13 | 1989-01-31 | Cook Incorporated | Endovascular stent and delivery system |
US4907336A (en) | 1987-03-13 | 1990-03-13 | Cook Incorporated | Method of making an endovascular stent and delivery system |
JPS63238872A (en) | 1987-03-25 | 1988-10-04 | テルモ株式会社 | Instrument for securing inner diameter of cavity of tubular organ and catheter equipped therewith |
US4857045A (en) | 1987-04-30 | 1989-08-15 | Schneider (Usa) Inc., A Pfizer Company | Atherectomy catheter |
US4817600A (en) | 1987-05-22 | 1989-04-04 | Medi-Tech, Inc. | Implantable filter |
US4794928A (en) | 1987-06-10 | 1989-01-03 | Kletschka Harold D | Angioplasty device and method of using the same |
US5059211A (en) | 1987-06-25 | 1991-10-22 | Duke University | Absorbable vascular stent |
US4867157A (en) | 1987-08-13 | 1989-09-19 | Baxter Travenol Laboratories, Inc. | Surgical cutting instrument |
US4898575A (en) | 1987-08-31 | 1990-02-06 | Medinnovations, Inc. | Guide wire following tunneling catheter system and method for transluminal arterial atherectomy |
US4857046A (en) | 1987-10-21 | 1989-08-15 | Cordis Corporation | Drive catheter having helical pump drive shaft |
US4873978A (en) * | 1987-12-04 | 1989-10-17 | Robert Ginsburg | Device and method for emboli retrieval |
FR2624747A1 (en) | 1987-12-18 | 1989-06-23 | Delsanti Gerard | REMOVABLE ENDO-ARTERIAL DEVICES FOR REPAIRING ARTERIAL WALL DECOLLEMENTS |
US5053044A (en) | 1988-01-11 | 1991-10-01 | Devices For Vascular Intervention, Inc. | Catheter and method for making intravascular incisions |
US4921478A (en) | 1988-02-23 | 1990-05-01 | C. R. Bard, Inc. | Cerebral balloon angioplasty system |
US4921484A (en) | 1988-07-25 | 1990-05-01 | Cordis Corporation | Mesh balloon catheter device |
US5071425A (en) | 1988-09-12 | 1991-12-10 | Devices For Vascular Intervention, Inc. | Atherectomy catheter and method of forming the same |
US5011488A (en) | 1988-12-07 | 1991-04-30 | Robert Ginsburg | Thrombus extraction system |
US4950277A (en) | 1989-01-23 | 1990-08-21 | Interventional Technologies, Inc. | Atherectomy cutting device with eccentric wire and method |
US4986807A (en) | 1989-01-23 | 1991-01-22 | Interventional Technologies, Inc. | Atherectomy cutter with radially projecting blade |
US5152777A (en) | 1989-01-25 | 1992-10-06 | Uresil Corporation | Device and method for providing protection from emboli and preventing occulsion of blood vessels |
US5087265A (en) | 1989-02-17 | 1992-02-11 | American Biomed, Inc. | Distal atherectomy catheter |
FR2643250B1 (en) | 1989-02-20 | 1997-12-26 | Lg Medical Sa | INTERVENTION DEVICE ON THE CARDIOVASCULAR SYSTEM ALLOWING IN PARTICULAR THE TREATMENT OF THROMBUS |
US4969891A (en) | 1989-03-06 | 1990-11-13 | Gewertz Bruce L | Removable vascular filter |
US5054500A (en) * | 1989-04-13 | 1991-10-08 | Littleford Philip O | Catheter guiding and positioning method |
US5934284A (en) | 1989-08-18 | 1999-08-10 | Endovascular Instruments, Inc | Method for increasing blood flow in vessels |
DE8910603U1 (en) | 1989-09-06 | 1989-12-07 | Guenther, Rolf W., Prof. Dr. | |
US5002560A (en) | 1989-09-08 | 1991-03-26 | Advanced Cardiovascular Systems, Inc. | Expandable cage catheter with a rotatable guide |
DE8910856U1 (en) * | 1989-09-12 | 1989-11-30 | Schneider (Europe) Ag, Zuerich, Ch | |
US5100425A (en) | 1989-09-14 | 1992-03-31 | Medintec R&D Limited Partnership | Expandable transluminal atherectomy catheter system and method for the treatment of arterial stenoses |
DE4030998C2 (en) | 1989-10-04 | 1995-11-23 | Ernst Peter Prof Dr M Strecker | Percutaneous vascular filter |
AU6376190A (en) | 1989-10-25 | 1991-05-02 | C.R. Bard Inc. | Occluding catheter and methods for treating cerebral arteries |
US5019088A (en) | 1989-11-07 | 1991-05-28 | Interventional Technologies Inc. | Ovoid atherectomy cutter |
US5085662A (en) | 1989-11-13 | 1992-02-04 | Scimed Life Systems, Inc. | Atherectomy catheter and related components |
US5195955A (en) | 1989-11-14 | 1993-03-23 | Don Michael T Anthony | Device for removal of embolic debris |
GB2238485B (en) | 1989-11-28 | 1993-07-14 | Cook William Europ | A collapsible filter for introduction in a blood vessel of a patient |
FR2655533A1 (en) | 1989-12-13 | 1991-06-14 | Lefebvre Jean Marie | FILTER CATHETER. |
US5421832A (en) | 1989-12-13 | 1995-06-06 | Lefebvre; Jean-Marie | Filter-catheter and method of manufacturing same |
US5007917A (en) | 1990-03-08 | 1991-04-16 | Stryker Corporation | Single blade cutter for arthroscopic surgery |
US5071407A (en) | 1990-04-12 | 1991-12-10 | Schneider (U.S.A.) Inc. | Radially expandable fixation member |
US5171233A (en) | 1990-04-25 | 1992-12-15 | Microvena Corporation | Snare-type probe |
US5100424A (en) | 1990-05-21 | 1992-03-31 | Cardiovascular Imaging Systems, Inc. | Intravascular catheter having combined imaging abrasion head |
CA2048307C (en) | 1990-08-14 | 1998-08-18 | Rolf Gunther | Method and apparatus for filtering blood in a blood vessel of a patient |
US5108419A (en) | 1990-08-16 | 1992-04-28 | Evi Corporation | Endovascular filter and method for use thereof |
DE4025825A1 (en) * | 1990-08-16 | 1992-02-20 | Cook William Europ | DEVICE FOR CRUSHING BLOOD CLOTS |
US5160342A (en) | 1990-08-16 | 1992-11-03 | Evi Corp. | Endovascular filter and method for use thereof |
US5100423A (en) | 1990-08-21 | 1992-03-31 | Medical Engineering & Development Institute, Inc. | Ablation catheter |
FR2666980B1 (en) | 1990-09-26 | 1993-07-23 | Lg Medical | BLOOD FILTRATION UNIT AND DEVICE FOR INTRODUCING SUCH A UNIT ONTO THE BLOOD PATH. |
US5449372A (en) | 1990-10-09 | 1995-09-12 | Scimed Lifesystems, Inc. | Temporary stent and methods for use and manufacture |
AU8850391A (en) | 1990-10-18 | 1992-05-20 | Ho Young Song | Self-expanding endovascular stent |
US5053008A (en) * | 1990-11-21 | 1991-10-01 | Sandeep Bajaj | Intracardiac catheter |
US5152771A (en) | 1990-12-31 | 1992-10-06 | The Board Of Supervisors Of Louisiana State University | Valve cutter for arterial by-pass surgery |
US5356423A (en) | 1991-01-04 | 1994-10-18 | American Medical Systems, Inc. | Resectable self-expanding stent |
EP0525176A4 (en) | 1991-02-19 | 1994-07-13 | Fischell Robert | Improved apparatus and method for atherectomy |
US5350398A (en) | 1991-05-13 | 1994-09-27 | Dusan Pavcnik | Self-expanding filter for percutaneous insertion |
US5569275A (en) | 1991-06-11 | 1996-10-29 | Microvena Corporation | Mechanical thrombus maceration device |
US5527354A (en) | 1991-06-28 | 1996-06-18 | Cook Incorporated | Stent formed of half-round wire |
US5314472A (en) | 1991-10-01 | 1994-05-24 | Cook Incorporated | Vascular stent |
US5415630A (en) | 1991-07-17 | 1995-05-16 | Gory; Pierre | Method for removably implanting a blood filter in a vein of the human body |
DE9109006U1 (en) | 1991-07-22 | 1991-10-10 | Schmitz-Rode, Thomas, Dipl.-Ing. Dr.Med., 5100 Aachen, De | |
US5443498A (en) | 1991-10-01 | 1995-08-22 | Cook Incorporated | Vascular stent and method of making and implanting a vacsular stent |
US5387235A (en) | 1991-10-25 | 1995-02-07 | Cook Incorporated | Expandable transluminal graft prosthesis for repair of aneurysm |
FR2683449A1 (en) | 1991-11-08 | 1993-05-14 | Cardon Alain | ENDOPROTHESIS FOR TRANSLUMINAL IMPLANTATION. |
US5395349A (en) | 1991-12-13 | 1995-03-07 | Endovascular Technologies, Inc. | Dual valve reinforced sheath and method |
FR2685190B1 (en) | 1991-12-23 | 1998-08-07 | Jean Marie Lefebvre | ROTARY ATHERECTOMY OR THROMBECTOMY DEVICE WITH CENTRIFUGAL TRANSVERSE DEVELOPMENT. |
US5626605A (en) | 1991-12-30 | 1997-05-06 | Scimed Life Systems, Inc. | Thrombosis filter |
US5507767A (en) | 1992-01-15 | 1996-04-16 | Cook Incorporated | Spiral stent |
CA2087132A1 (en) | 1992-01-31 | 1993-08-01 | Michael S. Williams | Stent capable of attachment within a body lumen |
US5405377A (en) | 1992-02-21 | 1995-04-11 | Endotech Ltd. | Intraluminal stent |
US5370683A (en) | 1992-03-25 | 1994-12-06 | Cook Incorporated | Vascular stent |
US5224953A (en) * | 1992-05-01 | 1993-07-06 | The Beth Israel Hospital Association | Method for treatment of obstructive portions of urinary passageways |
US5817102A (en) | 1992-05-08 | 1998-10-06 | Schneider (Usa) Inc. | Apparatus for delivering and deploying a stent |
US5366473A (en) | 1992-08-18 | 1994-11-22 | Ultrasonic Sensing And Monitoring Systems, Inc. | Method and apparatus for applying vascular grafts |
US5527338A (en) | 1992-09-02 | 1996-06-18 | Board Of Regents, The University Of Texas System | Intravascular device |
US5643297A (en) | 1992-11-09 | 1997-07-01 | Endovascular Instruments, Inc. | Intra-artery obstruction clearing apparatus and methods |
US5540707A (en) | 1992-11-13 | 1996-07-30 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
US5383926A (en) | 1992-11-23 | 1995-01-24 | Children's Medical Center Corporation | Re-expandable endoprosthesis |
US5318576A (en) | 1992-12-16 | 1994-06-07 | Plassche Jr Walter M | Endovascular surgery systems |
FR2699809B1 (en) | 1992-12-28 | 1995-02-17 | Celsa Lg | Device which can selectively constitute a temporary blood filter. |
US5569274A (en) | 1993-02-22 | 1996-10-29 | Heartport, Inc. | Endoscopic vascular clamping system and method |
US5354310A (en) | 1993-03-22 | 1994-10-11 | Cordis Corporation | Expandable temporary graft |
JP2545727B2 (en) | 1993-04-19 | 1996-10-23 | 工業技術院長 | Deodorant lamp and its manufacturing method |
US5456667A (en) | 1993-05-20 | 1995-10-10 | Advanced Cardiovascular Systems, Inc. | Temporary stenting catheter with one-piece expandable segment |
US5425765A (en) | 1993-06-25 | 1995-06-20 | Tiefenbrun; Jonathan | Surgical bypass method |
US5419774A (en) | 1993-07-13 | 1995-05-30 | Scimed Life Systems, Inc. | Thrombus extraction device |
US5366464A (en) | 1993-07-22 | 1994-11-22 | Belknap John C | Atherectomy catheter device |
US5462529A (en) | 1993-09-29 | 1995-10-31 | Technology Development Center | Adjustable treatment chamber catheter |
US5634897A (en) | 1993-10-08 | 1997-06-03 | Lake Region Manufacturing, Inc. | Rheolytic occlusion removal catheter system and method |
FR2713081B1 (en) | 1993-11-29 | 1996-01-12 | Celsa Lg | Improved blood filter with two series of petal legs. |
DE9319267U1 (en) | 1993-12-15 | 1994-02-24 | Vorwerk Dierk Dr | Aortic endoprosthesis |
US5792300A (en) | 1994-01-21 | 1998-08-11 | Cordis Corporation | Perfusion catheter and striped extrusion method of manufacture |
US5683451A (en) | 1994-06-08 | 1997-11-04 | Cardiovascular Concepts, Inc. | Apparatus and methods for deployment release of intraluminal prostheses |
EP0686379B2 (en) | 1994-06-08 | 2007-03-28 | Cardiovascular Concepts, Inc. | Vascular graft |
DE9409484U1 (en) | 1994-06-11 | 1994-08-04 | Naderlinger Eduard | Vena cava thrombus filter |
EP0954244A1 (en) | 1994-07-01 | 1999-11-10 | SciMed Life Systems, Inc. | Intravascular device utilizing fluid to extract occlusive material |
US5476104A (en) | 1994-08-01 | 1995-12-19 | Sheahon; John A. | Cervical and endometrial biopsy instrument |
US5512044A (en) | 1994-10-11 | 1996-04-30 | Duer; Edward Y. | Embolic cutting catheter |
US5658296A (en) | 1994-11-21 | 1997-08-19 | Boston Scientific Corporation | Method for making surgical retrieval baskets |
US5709704A (en) | 1994-11-30 | 1998-01-20 | Boston Scientific Corporation | Blood clot filtering |
US5928218A (en) | 1994-12-16 | 1999-07-27 | Gelbfish; Gary A. | Medical material removal method and associated instrumentation |
US5549626A (en) | 1994-12-23 | 1996-08-27 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Vena caval filter |
JPH08187294A (en) | 1995-01-12 | 1996-07-23 | Clinical Supply:Kk | Filter for thrombus catching |
WO1996030073A1 (en) | 1995-03-30 | 1996-10-03 | Heartport, Inc. | Endovascular cardiac venting catheter and method |
NL1000105C2 (en) | 1995-04-10 | 1996-10-11 | Cordis Europ | Catheter with filter and thrombi draining device. |
US5795322A (en) | 1995-04-10 | 1998-08-18 | Cordis Corporation | Catheter with filter and thrombus-discharge device |
NL1001410C2 (en) | 1995-05-19 | 1996-11-20 | Cordis Europ | Medical device for long-term residence in a body. |
US5681347A (en) | 1995-05-23 | 1997-10-28 | Boston Scientific Corporation | Vena cava filter delivery system |
US5938645A (en) | 1995-05-24 | 1999-08-17 | Boston Scientific Corporation Northwest Technology Center Inc. | Percutaneous aspiration catheter system |
US5833650A (en) | 1995-06-05 | 1998-11-10 | Percusurge, Inc. | Catheter apparatus and method for treating occluded vessels |
FR2737653B1 (en) | 1995-08-10 | 1997-09-19 | Braun Celsa Sa | DEFINITIVE FILTER COMPRISING AN ORIFICE FOR THE PASSAGE OF MEDICAL DEVICES AND ITS MANUFACTURING METHOD |
US5925016A (en) | 1995-09-27 | 1999-07-20 | Xrt Corp. | Systems and methods for drug delivery including treating thrombosis by driving a drug or lytic agent through the thrombus by pressure |
US5779716A (en) | 1995-10-06 | 1998-07-14 | Metamorphic Surgical Devices, Inc. | Device for removing solid objects from body canals, cavities and organs |
US5989281A (en) | 1995-11-07 | 1999-11-23 | Embol-X, Inc. | Cannula with associated filter and methods of use during cardiac surgery |
US5769816A (en) | 1995-11-07 | 1998-06-23 | Embol-X, Inc. | Cannula with associated filter |
US5749848A (en) * | 1995-11-13 | 1998-05-12 | Cardiovascular Imaging Systems, Inc. | Catheter system having imaging, balloon angioplasty, and stent deployment capabilities, and method of use for guided stent deployment |
US5695519A (en) | 1995-11-30 | 1997-12-09 | American Biomed, Inc. | Percutaneous filter for carotid angioplasty |
US5728066A (en) | 1995-12-13 | 1998-03-17 | Daneshvar; Yousef | Injection systems and methods |
US5827429A (en) | 1996-01-18 | 1998-10-27 | Filtertek Inc. | Intravenous filter device |
NL1002423C2 (en) | 1996-02-22 | 1997-08-25 | Cordis Europ | Temporary filter catheter. |
US5935139A (en) | 1996-05-03 | 1999-08-10 | Boston Scientific Corporation | System for immobilizing or manipulating an object in a tract |
US6048331A (en) * | 1996-05-14 | 2000-04-11 | Embol-X, Inc. | Cardioplegia occluder |
CA2254831C (en) * | 1996-05-14 | 2006-10-17 | Embol-X, Inc. | Aortic occluder with associated filter and methods of use during cardiac surgery |
US5833644A (en) | 1996-05-20 | 1998-11-10 | Percusurge, Inc. | Method for emboli containment |
US6270477B1 (en) | 1996-05-20 | 2001-08-07 | Percusurge, Inc. | Catheter for emboli containment |
US6022336A (en) * | 1996-05-20 | 2000-02-08 | Percusurge, Inc. | Catheter system for emboli containment |
US20010049517A1 (en) * | 1997-03-06 | 2001-12-06 | Gholam-Reza Zadno-Azizi | Method for containing and removing occlusions in the carotid arteries |
US6152909A (en) | 1996-05-20 | 2000-11-28 | Percusurge, Inc. | Aspiration system and method |
US6544276B1 (en) * | 1996-05-20 | 2003-04-08 | Medtronic Ave. Inc. | Exchange method for emboli containment |
US5797952A (en) | 1996-06-21 | 1998-08-25 | Localmed, Inc. | System and method for delivering helical stents |
NL1003497C2 (en) | 1996-07-03 | 1998-01-07 | Cordis Europ | Catheter with temporary vena-cava filter. |
US6077295A (en) * | 1996-07-15 | 2000-06-20 | Advanced Cardiovascular Systems, Inc. | Self-expanding stent delivery system |
US5669933A (en) | 1996-07-17 | 1997-09-23 | Nitinol Medical Technologies, Inc. | Removable embolus blood clot filter |
US5662671A (en) | 1996-07-17 | 1997-09-02 | Embol-X, Inc. | Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries |
US6066158A (en) * | 1996-07-25 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot encasing and removal wire |
US6080170A (en) * | 1996-07-26 | 2000-06-27 | Kensey Nash Corporation | System and method of use for revascularizing stenotic bypass grafts and other occluded blood vessels |
US5779721A (en) | 1996-07-26 | 1998-07-14 | Kensey Nash Corporation | System and method of use for revascularizing stenotic bypass grafts and other blood vessels |
US5893867A (en) | 1996-11-06 | 1999-04-13 | Percusurge, Inc. | Stent positioning apparatus and method |
US5876367A (en) | 1996-12-05 | 1999-03-02 | Embol-X, Inc. | Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries |
FR2758078B1 (en) | 1997-01-03 | 1999-07-16 | Braun Celsa Sa | BLOOD FILTER WITH IMPROVED PERMEABILITY |
US5882329A (en) | 1997-02-12 | 1999-03-16 | Prolifix Medical, Inc. | Apparatus and method for removing stenotic material from stents |
US5800457A (en) | 1997-03-05 | 1998-09-01 | Gelbfish; Gary A. | Intravascular filter and associated methodology |
US6152946A (en) | 1998-03-05 | 2000-11-28 | Scimed Life Systems, Inc. | Distal protection device and method |
EP0934092A4 (en) * | 1997-03-06 | 2008-03-26 | Boston Scient Scimed Inc | Distal protection device and method |
AU6688398A (en) | 1997-03-06 | 1998-09-22 | Percusurge, Inc. | Intravascular aspiration system |
US5814064A (en) | 1997-03-06 | 1998-09-29 | Scimed Life Systems, Inc. | Distal protection device |
US5827324A (en) * | 1997-03-06 | 1998-10-27 | Scimed Life Systems, Inc. | Distal protection device |
US5906618A (en) | 1997-03-20 | 1999-05-25 | Vanderbilt University | Microcatheter with auxiliary parachute guide structure |
JP4083241B2 (en) * | 1997-04-23 | 2008-04-30 | アーテミス・メディカル・インコーポレイテッド | Bifurcated stent and distal protection system |
US5846260A (en) | 1997-05-08 | 1998-12-08 | Embol-X, Inc. | Cannula with a modular filter for filtering embolic material |
US5911734A (en) * | 1997-05-08 | 1999-06-15 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
US5954745A (en) | 1997-05-16 | 1999-09-21 | Gertler; Jonathan | Catheter-filter set having a compliant seal |
US6059814A (en) | 1997-06-02 | 2000-05-09 | Medtronic Ave., Inc. | Filter for filtering fluid in a bodily passageway |
US5800525A (en) | 1997-06-04 | 1998-09-01 | Vascular Science, Inc. | Blood filter |
US5848964A (en) | 1997-06-06 | 1998-12-15 | Samuels; Shaun Lawrence Wilkie | Temporary inflatable filter device and method of use |
US5947995A (en) | 1997-06-06 | 1999-09-07 | Samuels; Shaun Lawrence Wilkie | Method and apparatus for removing blood clots and other objects |
US5941896A (en) | 1997-09-08 | 1999-08-24 | Montefiore Hospital And Medical Center | Filter and method for trapping emboli during endovascular procedures |
FR2768326B1 (en) | 1997-09-18 | 1999-10-22 | De Bearn Olivier Despalle | TEMPORARY BLOOD FILTER |
US5925063A (en) | 1997-09-26 | 1999-07-20 | Khosravi; Farhad | Coiled sheet valve, filter or occlusive device and methods of use |
US5928203A (en) | 1997-10-01 | 1999-07-27 | Boston Scientific Corporation | Medical fluid infusion and aspiration |
US5908435A (en) | 1997-10-23 | 1999-06-01 | Samuels; Shaun L. W. | Expandable lumen device and method of use |
DE69828634T2 (en) | 1997-11-03 | 2005-12-01 | C.R. Bard, Inc. | GUIDE WIRE FOR TEMPORARY BLOOD FILTERS |
US6013085A (en) | 1997-11-07 | 2000-01-11 | Howard; John | Method for treating stenosis of the carotid artery |
US6295990B1 (en) | 1998-02-03 | 2001-10-02 | Salient Interventional Systems, Inc. | Methods and systems for treating ischemia |
US5989210A (en) | 1998-02-06 | 1999-11-23 | Possis Medical, Inc. | Rheolytic thrombectomy catheter and method of using same |
US5925060A (en) * | 1998-03-13 | 1999-07-20 | B. Braun Celsa | Covered self-expanding vascular occlusion device |
US6007557A (en) | 1998-04-29 | 1999-12-28 | Embol-X, Inc. | Adjustable blood filtration system |
US6231588B1 (en) * | 1998-08-04 | 2001-05-15 | Percusurge, Inc. | Low profile catheter for angioplasty and occlusion |
US6051014A (en) | 1998-10-13 | 2000-04-18 | Embol-X, Inc. | Percutaneous filtration catheter for valve repair surgery and methods of use |
US5989271A (en) | 1998-11-09 | 1999-11-23 | Possis Medical, Inc. | Flexible tip rheolytic thrombectomy catheter and method of constructing same |
US6171327B1 (en) | 1999-02-24 | 2001-01-09 | Scimed Life Systems, Inc. | Intravascular filter and method |
US6068645A (en) | 1999-06-07 | 2000-05-30 | Tu; Hosheng | Filter system and methods for removing blood clots and biological material |
US6179859B1 (en) | 1999-07-16 | 2001-01-30 | Baff Llc | Emboli filtration system and methods of use |
US6530939B1 (en) | 1999-07-30 | 2003-03-11 | Incept, Llc | Vascular device having articulation region and methods of use |
US6203561B1 (en) | 1999-07-30 | 2001-03-20 | Incept Llc | Integrated vascular device having thrombectomy element and vascular filter and methods of use |
US6214026B1 (en) | 1999-07-30 | 2001-04-10 | Incept Llc | Delivery system for a vascular device with articulation region |
US6179861B1 (en) | 1999-07-30 | 2001-01-30 | Incept Llc | Vascular device having one or more articulation regions and methods of use |
US6142987A (en) | 1999-08-03 | 2000-11-07 | Scimed Life Systems, Inc. | Guided filter with support wire and methods of use |
US6168579B1 (en) * | 1999-08-04 | 2001-01-02 | Scimed Life Systems, Inc. | Filter flush system and methods of use |
US6540722B1 (en) * | 1999-12-30 | 2003-04-01 | Advanced Cardiovascular Systems, Inc. | Embolic protection devices |
US6443926B1 (en) | 2000-02-01 | 2002-09-03 | Harold D. Kletschka | Embolic protection device having expandable trap |
US6485500B1 (en) | 2000-03-21 | 2002-11-26 | Advanced Cardiovascular Systems, Inc. | Emboli protection system |
-
1999
- 1999-08-04 US US09/369,052 patent/US6168579B1/en not_active Expired - Lifetime
-
2000
- 2000-08-03 WO PCT/US2000/040560 patent/WO2001010343A1/en active IP Right Grant
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- 2000-08-03 AT AT00965582T patent/ATE328550T1/en not_active IP Right Cessation
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- 2003-07-17 US US10/621,972 patent/US8444665B2/en not_active Expired - Fee Related
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CA2345655A1 (en) | 2001-02-15 |
WO2001010343A9 (en) | 2002-09-26 |
US6620148B1 (en) | 2003-09-16 |
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JP4667690B2 (en) | 2011-04-13 |
EP1117344A1 (en) | 2001-07-25 |
DE60028528D1 (en) | 2006-07-20 |
WO2001010343A1 (en) | 2001-02-15 |
DE1117344T1 (en) | 2002-06-13 |
US6168579B1 (en) | 2001-01-02 |
US8444665B2 (en) | 2013-05-21 |
DE60028528T2 (en) | 2007-01-04 |
EP1117344B1 (en) | 2006-06-07 |
JP2003506141A (en) | 2003-02-18 |
US20040006370A1 (en) | 2004-01-08 |
ATE328550T1 (en) | 2006-06-15 |
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