CA2353096A1 - Automated system for the radiation treatment of a desired area within the body of a patient - Google Patents
Automated system for the radiation treatment of a desired area within the body of a patient Download PDFInfo
- Publication number
- CA2353096A1 CA2353096A1 CA002353096A CA2353096A CA2353096A1 CA 2353096 A1 CA2353096 A1 CA 2353096A1 CA 002353096 A CA002353096 A CA 002353096A CA 2353096 A CA2353096 A CA 2353096A CA 2353096 A1 CA2353096 A1 CA 2353096A1
- Authority
- CA
- Canada
- Prior art keywords
- transfer device
- catheter
- fluid
- cartridge
- lumen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000005855 radiation Effects 0.000 title claims 2
- 239000012530 fluid Substances 0.000 claims abstract 54
- 239000000463 material Substances 0.000 claims abstract 3
- 230000002572 peristaltic effect Effects 0.000 claims abstract 3
- 239000010453 quartz Substances 0.000 claims abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract 2
- 230000003287 optical effect Effects 0.000 claims 5
- 238000005286 illumination Methods 0.000 claims 4
- 230000001681 protective effect Effects 0.000 claims 2
- 239000004642 Polyimide Substances 0.000 claims 1
- 230000000903 blocking effect Effects 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 239000000835 fiber Substances 0.000 claims 1
- 230000010412 perfusion Effects 0.000 claims 1
- 229920001721 polyimide Polymers 0.000 claims 1
- 230000002441 reversible effect Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
- A61N2005/1008—Apparatus for temporary insertion of sources, e.g. afterloaders
Abstract
This invention is a transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient in which the transfer device has an integral pump (66) for pressurizing, for circulating fluid through a fluid path defined by the transfer device and associated catheter. A removable fluid cartridge (50) is provided including a reservoir (52) from which fluid is drawn by the pump (66) and into which fluid is returned after being circulated through the fluid path.
The pump (66) may be a peristaltic pump (66) and the fluid cartridge (50) may include an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device. The fluid pick-up is sized in length so that the inlet is always submerged in the fluid regardless of the orientation of the transfer device. A removable treatment cartridge (70) having a lumen forming part of the fluid path may also be provided, and a storage sleeve for the treatment cartridge (70) may be of a radiation-blocking material, such as quartz.
The pump (66) may be a peristaltic pump (66) and the fluid cartridge (50) may include an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device. The fluid pick-up is sized in length so that the inlet is always submerged in the fluid regardless of the orientation of the transfer device. A removable treatment cartridge (70) having a lumen forming part of the fluid path may also be provided, and a storage sleeve for the treatment cartridge (70) may be of a radiation-blocking material, such as quartz.
Claims (23)
1. In a transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient by at least one treating element advanced through a lumen in the transfer device into a lumen of a separate catheter by means of pressurized fluid, the transfer device and the catheter defining a fluid path for pressurized fluid, the transfer device further comprising an integral pump for pressurizing and circulating the fluid through the fluid path and a removable fluid cartridge including a reservoir from which fluid is drawn by the pump and to which fluid is returned after being circulated through the fluid path.
2. The transfer device of Claim 1 wherein the integral pump comprises a peristaltic pump.
3. The transfer device of Claim 1 wherein the integral pump comprises a reversible peristaltic pump.
4. The transfer device of Claim 1 wherein the fluid cartridge includes an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device and sized in length so that the inlet is always submerged in fluid regardless of the orientation of the transfer device.
5. The transfer device of Claim 1 further comprising a removable cartridge including a storage sleeve for housing the treating element, the sleeve having a lumen forming part of the fluid path.
6. The transfer device of Claim 5 wherein the storage sleeve comprises a radiation-blocking material.
7. The transfer device of Claim 6 wherein the radiation blocking material comprises quartz.
8. The transfer device of Claim 5 wherein the removable cartridge further comprises a memory for storing and indicating selected information about the treating element.
9. The transfer device of Claim 1 further comprising an external access point to the fluid path adapted to receive an external source of pressurized fluid.
10. In a transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient by at least one treating element advanced through a lumen in the transfer device into a lumen of a separate catheter by means of pressurized fluid, the transfer device and catheter defining a fluid path for pressurized fluid, the transfer device being adapted to receive a fluid cartridge for holding the fluid and a source cartridge for storing the treating element, a system for preventing operation of the transfer device unless each of the catheter, fluid cartridge and source cartridge are attached thereto comprising:
an illumination source and optical sensor located in the transfer device in proximity to where each of the catheter, fluid cartridge and source cartridge is received by the transfer device, each illumination source being located with respect to its optical sensor so that the optical sensor is able to receive light from its illumination source only if the catheter, fluid cartridge or source cartridge is not received by the transfer device, and the optical sensor being blocked from receiving light from the illumination source when the catheter, fluid cartridge or source cartridge are received by the transfer device;
a microprocessor for controlling the movement of the treating element from the transfer device to the catheter, the microprocessor preventing operation of the transfer device upon receiving a signal from any of the optical sensors indicating that at least one of the catheter, fluid cartridge and source cartridge is not attached to the transfer device.
an illumination source and optical sensor located in the transfer device in proximity to where each of the catheter, fluid cartridge and source cartridge is received by the transfer device, each illumination source being located with respect to its optical sensor so that the optical sensor is able to receive light from its illumination source only if the catheter, fluid cartridge or source cartridge is not received by the transfer device, and the optical sensor being blocked from receiving light from the illumination source when the catheter, fluid cartridge or source cartridge are received by the transfer device;
a microprocessor for controlling the movement of the treating element from the transfer device to the catheter, the microprocessor preventing operation of the transfer device upon receiving a signal from any of the optical sensors indicating that at least one of the catheter, fluid cartridge and source cartridge is not attached to the transfer device.
11. The transfer device of Claim 10 further comprising a graphical user interface controlled by the microprocessor for visually indicating which of one or more of the catheter, fluid cartridge and source cartridge is not attached to the catheter when operation of the transfer device is prevented.
12. A catheter having a proximal end and a distal end for use in a intraluminal treatment system wherein a treating element is advanced from the proximal end of the catheter to the distal end by means of pressurized fluid, the catheter comprising:
first, second, third and fourth lumens extending substantially from the proximal end to the distal end of the catheter, the first lumen being sized to slidingly receive the treating element but to prevent the treating element from exiting the first lumen at the distal end of the catheter, the first lumen being in fluid communication with the second and third lumens at the distal end thereof, and the fourth lumen being open at the distal end and sized to receive a guidewire.
first, second, third and fourth lumens extending substantially from the proximal end to the distal end of the catheter, the first lumen being sized to slidingly receive the treating element but to prevent the treating element from exiting the first lumen at the distal end of the catheter, the first lumen being in fluid communication with the second and third lumens at the distal end thereof, and the fourth lumen being open at the distal end and sized to receive a guidewire.
13. The catheter of Claim 12 wherein the fourth lumen includes a protective liner.
14. The catheter of Claim 14 wherein the protective liner is polyimide.
15. The catheter of Claim 12 wherein the proximal and distal ends of the catheter are of different stiffness and flexibility, and the distal end has a cross-sectional area smaller than the proximal end of the catheter and a non-circular cross-sectional shape so as to permit perfusion.
16. The catheter of Claim 15 wherein the proximal end is fused to the distal end.
17. The catheter of Claim 15 wherein the proximal end and distal end are formed through a single variable extrusion.
18. In a transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient by at least one treating element advanced through a lumen in the transfer device into a lumen of a separate catheter by means of pressurized fluid, the transfer device and catheter defining a fluid path for pressurized fluid and a treating element residing in a cartridge removably received by the transfer device, the transfer device further comprising:
a gate moveable between first and second positions to selectively permit or prevent the treating element from moving from the treating element cartridge to the catheter;
a first release button to permit disassembly of the catheter from the transfer device upon manipulation of the first button;
a second release button to permit the treating element cartridge to be separated from the transfer device upon manipulation of the second button;
an actuator assembly to control the gate and to permit manipulation of the first and second release buttons only when the actuator assembly controls the gate to prevent the treating element from moving from the treating element cartridge to the catheter.
a gate moveable between first and second positions to selectively permit or prevent the treating element from moving from the treating element cartridge to the catheter;
a first release button to permit disassembly of the catheter from the transfer device upon manipulation of the first button;
a second release button to permit the treating element cartridge to be separated from the transfer device upon manipulation of the second button;
an actuator assembly to control the gate and to permit manipulation of the first and second release buttons only when the actuator assembly controls the gate to prevent the treating element from moving from the treating element cartridge to the catheter.
19. The transfer device of Claim 18 wherein the actuator assembly comprises:
a worm gear;
a drive motor for rotating the worm gear;
a mounting member secured to the worm gear that moves linearly between first and second positions upon rotation of the worm gear;
a plate secured to the mounting member for engaging the gate and moving with the mounting member to move the gate between its first and second positions;
a post secured to the mounting member and moveable therewith to a position to prevent manipulation of the first release button when the plate moves the gate to its first position; and a rod secured to the mounting member and moveable therewith to a position to prevent manipulation of the second release button when the plate moves the gate to its first position.
a worm gear;
a drive motor for rotating the worm gear;
a mounting member secured to the worm gear that moves linearly between first and second positions upon rotation of the worm gear;
a plate secured to the mounting member for engaging the gate and moving with the mounting member to move the gate between its first and second positions;
a post secured to the mounting member and moveable therewith to a position to prevent manipulation of the first release button when the plate moves the gate to its first position; and a rod secured to the mounting member and moveable therewith to a position to prevent manipulation of the second release button when the plate moves the gate to its first position.
20. In a transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient by at least one treating element advanced from a translucent storage sleeve having a lumen into a lumen of a separate catheter by means of pressurized fluid, a system for detecting the presence or absence of the treating element in the translucent storage sleeve comprising;
a light source including a jacketed fiber optic bundle disposed on a first side of the storage sleeve to produce a plane of light that intersects at least a portion of the storage sleeve lumen;
a linear array of photosensors disposed on a second side of the storage sleeve so as to measure light from the light source;
a microprocessor for comparing the amount of light measured by the photosensors to a reference amount corresponding to the amount of light measured by the photosensors when the treating element is not within the lumen of the storage sleeve.
a light source including a jacketed fiber optic bundle disposed on a first side of the storage sleeve to produce a plane of light that intersects at least a portion of the storage sleeve lumen;
a linear array of photosensors disposed on a second side of the storage sleeve so as to measure light from the light source;
a microprocessor for comparing the amount of light measured by the photosensors to a reference amount corresponding to the amount of light measured by the photosensors when the treating element is not within the lumen of the storage sleeve.
21. The transfer device of Claim 20 wherein the light source comprises an infrared light source.
22. The transfer device of Claim 20 wherein the light source comprises a laser diode.
23. In a transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient by at least one treating element advanced through a lumen in the transfer device into a lumen of a separate catheter by means of pressurized fluid, the transfer device and catheter defining a fluid path for pressurized fluid, the transfer device being adapted to receive a fluid cartridge for holding the fluid and a source cartridge for storing the treating element, a system for preventing operation of the transfer device unless each of the catheter, fluid cartridge and source cartridge are attached thereto comprising:
a sensor located in the transfer device in proximity to where each of the catheter, fluid cartridge and source cartridge is received by the transfer device, each sensor generating a signal based on whether each of the catheter, fluid cartridge or source cartridge is received by the transfer device;
a microprocessor for controlling the movement of the treating element from the transfer device to the catheter, the microprocessor preventing operation of the transfer device upon receiving a signal from any of the sensors indicating that at least one of the catheter, fluid cartridge and source cartridge is not attached to the transfer device.
a sensor located in the transfer device in proximity to where each of the catheter, fluid cartridge and source cartridge is received by the transfer device, each sensor generating a signal based on whether each of the catheter, fluid cartridge or source cartridge is received by the transfer device;
a microprocessor for controlling the movement of the treating element from the transfer device to the catheter, the microprocessor preventing operation of the transfer device upon receiving a signal from any of the sensors indicating that at least one of the catheter, fluid cartridge and source cartridge is not attached to the transfer device.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002635958A CA2635958A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634616A CA2634616A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634619A CA2634619A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634649A CA2634649A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11340698P | 1998-12-22 | 1998-12-22 | |
| US60/113,406 | 1998-12-22 | ||
| PCT/US1999/030000 WO2000037137A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
Related Child Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002635958A Division CA2635958A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634649A Division CA2634649A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634616A Division CA2634616A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634619A Division CA2634619A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2353096A1 true CA2353096A1 (en) | 2000-06-29 |
| CA2353096C CA2353096C (en) | 2011-03-22 |
Family
ID=22349210
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002635958A Abandoned CA2635958A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634616A Abandoned CA2634616A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634619A Abandoned CA2634619A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA2353096A Expired - Fee Related CA2353096C (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634649A Abandoned CA2634649A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002635958A Abandoned CA2635958A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634616A Abandoned CA2634616A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
| CA002634619A Abandoned CA2634619A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002634649A Abandoned CA2634649A1 (en) | 1998-12-22 | 1999-12-22 | Automated system for the radiation treatment of a desired area within the body of a patient |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US6659934B1 (en) |
| EP (2) | EP1808196A3 (en) |
| JP (1) | JP2002532209A (en) |
| KR (1) | KR20010099922A (en) |
| CN (1) | CN1331611A (en) |
| AT (1) | ATE361771T1 (en) |
| AU (1) | AU755009B2 (en) |
| BR (1) | BR9916408A (en) |
| CA (5) | CA2635958A1 (en) |
| DE (1) | DE69936063T2 (en) |
| MX (1) | MXPA01005928A (en) |
| NO (1) | NO20013087L (en) |
| WO (1) | WO2000037137A1 (en) |
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| DE102005027677B4 (en) * | 2005-06-15 | 2019-07-04 | Siemens Healthcare Gmbh | Device for automatic replacement of instruments in minimally invasive procedures |
| EP2214608B1 (en) | 2007-11-08 | 2015-03-04 | Alimera Sciences, Inc. | Ocular implantation device |
| US20090130017A1 (en) * | 2007-11-19 | 2009-05-21 | Searete Llc | Targeted short-lived drug delivery |
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| US9717896B2 (en) | 2007-12-18 | 2017-08-01 | Gearbox, Llc | Treatment indications informed by a priori implant information |
| US20090287120A1 (en) | 2007-12-18 | 2009-11-19 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Circulatory monitoring systems and methods |
| JP5192873B2 (en) | 2008-03-28 | 2013-05-08 | パナソニック株式会社 | Hair growth control light irradiation device |
| EP2392894A3 (en) * | 2009-01-23 | 2012-10-24 | Acro Associates | Fluid control platform, fluid control systems, intelligent fluid control components and optical aperture sensors |
| US20110106069A1 (en) * | 2009-10-29 | 2011-05-05 | Brooks Robert J | Laser focusing tip protection |
| US9332999B2 (en) | 2012-08-13 | 2016-05-10 | Covidien Lp | Apparatus and methods for clot disruption and evacuation |
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1999
- 1999-12-22 KR KR1020017008040A patent/KR20010099922A/en active IP Right Grant
- 1999-12-22 BR BR9916408-6A patent/BR9916408A/en not_active IP Right Cessation
- 1999-12-22 DE DE69936063T patent/DE69936063T2/en not_active Expired - Lifetime
- 1999-12-22 CA CA002635958A patent/CA2635958A1/en not_active Abandoned
- 1999-12-22 CA CA002634616A patent/CA2634616A1/en not_active Abandoned
- 1999-12-22 US US09/469,510 patent/US6659934B1/en not_active Expired - Lifetime
- 1999-12-22 CA CA002634619A patent/CA2634619A1/en not_active Abandoned
- 1999-12-22 EP EP07007107A patent/EP1808196A3/en not_active Withdrawn
- 1999-12-22 EP EP99968900A patent/EP1140274B1/en not_active Expired - Lifetime
- 1999-12-22 JP JP2000589244A patent/JP2002532209A/en active Pending
- 1999-12-22 AU AU27101/00A patent/AU755009B2/en not_active Ceased
- 1999-12-22 MX MXPA01005928A patent/MXPA01005928A/en unknown
- 1999-12-22 CA CA2353096A patent/CA2353096C/en not_active Expired - Fee Related
- 1999-12-22 WO PCT/US1999/030000 patent/WO2000037137A1/en active IP Right Grant
- 1999-12-22 CN CN99814974A patent/CN1331611A/en active Pending
- 1999-12-22 AT AT99968900T patent/ATE361771T1/en not_active IP Right Cessation
- 1999-12-22 CA CA002634649A patent/CA2634649A1/en not_active Abandoned
-
2001
- 2001-06-21 NO NO20013087A patent/NO20013087L/en unknown
-
2003
- 2003-10-27 US US10/694,097 patent/US7066873B2/en not_active Expired - Lifetime
- 2003-10-27 US US10/694,032 patent/US20040097777A1/en not_active Abandoned
- 2003-10-27 US US10/694,289 patent/US7311656B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2634616A1 (en) | 2000-06-29 |
| DE69936063D1 (en) | 2007-06-21 |
| EP1140274A1 (en) | 2001-10-10 |
| CA2635958A1 (en) | 2000-06-29 |
| NO20013087L (en) | 2001-08-21 |
| US7066873B2 (en) | 2006-06-27 |
| EP1808196A3 (en) | 2009-04-01 |
| EP1140274A4 (en) | 2005-04-13 |
| EP1808196A2 (en) | 2007-07-18 |
| CA2634649A1 (en) | 2000-06-29 |
| CA2353096C (en) | 2011-03-22 |
| US20040097778A1 (en) | 2004-05-20 |
| JP2002532209A (en) | 2002-10-02 |
| AU755009B2 (en) | 2002-11-28 |
| KR20010099922A (en) | 2001-11-09 |
| ATE361771T1 (en) | 2007-06-15 |
| NO20013087D0 (en) | 2001-06-21 |
| AU2710100A (en) | 2000-07-12 |
| US7311656B2 (en) | 2007-12-25 |
| BR9916408A (en) | 2001-09-25 |
| US20040097777A1 (en) | 2004-05-20 |
| MXPA01005928A (en) | 2002-09-18 |
| CA2634619A1 (en) | 2000-06-29 |
| DE69936063T2 (en) | 2008-01-03 |
| US6659934B1 (en) | 2003-12-09 |
| EP1140274B1 (en) | 2007-05-09 |
| US20040092787A1 (en) | 2004-05-13 |
| WO2000037137A1 (en) | 2000-06-29 |
| CN1331611A (en) | 2002-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20121224 |