CA2355661A1 - Apparatus and method for obtaining transepithelial specimen of a body surface using a non-lacerating technique - Google Patents

Apparatus and method for obtaining transepithelial specimen of a body surface using a non-lacerating technique Download PDF

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Publication number
CA2355661A1
CA2355661A1 CA002355661A CA2355661A CA2355661A1 CA 2355661 A1 CA2355661 A1 CA 2355661A1 CA 002355661 A CA002355661 A CA 002355661A CA 2355661 A CA2355661 A CA 2355661A CA 2355661 A1 CA2355661 A1 CA 2355661A1
Authority
CA
Canada
Prior art keywords
brush
specimen
handle
body surface
technique
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002355661A
Other languages
French (fr)
Other versions
CA2355661C (en
Inventor
Neal M. Lonky
Jeremy James Michael Papadopoulos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CDX LABORATORIES Inc
SHARED MEDICAL RESOURCES LLC
Original Assignee
The Oralscan/Trylon Joint Venture
Neal M. Lonky
Jeremy James Michael Papadopoulos
Cdx Laboratories, Inc.
Shared Medical Resources, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22241676&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2355661(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The Oralscan/Trylon Joint Venture, Neal M. Lonky, Jeremy James Michael Papadopoulos, Cdx Laboratories, Inc., Shared Medical Resources, Llc filed Critical The Oralscan/Trylon Joint Venture
Publication of CA2355661A1 publication Critical patent/CA2355661A1/en
Application granted granted Critical
Publication of CA2355661C publication Critical patent/CA2355661C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46B—BRUSHES
    • A46B3/00—Brushes characterised by the way in which the bristles are fixed or joined in or on the brush body or carrier
    • A46B3/18—Brushes characterised by the way in which the bristles are fixed or joined in or on the brush body or carrier the bristles being fixed on or between belts or wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0291—Instruments for taking cell samples or for biopsy for uterus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/24—Surgical instruments, devices or methods, e.g. tourniquets for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B2010/0216—Sampling brushes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B2017/320004—Surgical cutting instruments abrasive
    • A61B2017/320012—Brushes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • A61B2017/320084—Irrigation sleeves

Abstract

A non-lacerational technique to collect cells in an oral cavity utilizes a brush with bristles (40) which have an abrading surface that collect cells from the superficial, intermediate, and basal layers of the oral tissue. The brush includes a handle (20), and a brush head (26) extending from the distal end (24) of the handle (20). The brush head (26) includes at least one braided wire or cable (30) which forms a toroid (34) perpendicular to the longitudinal axis of the handle (20). Arrays (42) of bristles (40) are secured to the brush within the twisted wires or cable (30).
CA002355661A 1998-07-23 1999-07-23 Apparatus and method for obtaining transepithelial specimen of a body surface using a non-lacerating technique Expired - Lifetime CA2355661C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9391098P 1998-07-23 1998-07-23
US60/093,910 1998-07-23
PCT/US1999/016620 WO2000004833A1 (en) 1998-07-23 1999-07-23 Apparatus and method for obtaining transepithelial specimen of a body surface using a non-lacerating technique

Publications (2)

Publication Number Publication Date
CA2355661A1 true CA2355661A1 (en) 2000-02-03
CA2355661C CA2355661C (en) 2006-04-11

Family

ID=22241676

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002355661A Expired - Lifetime CA2355661C (en) 1998-07-23 1999-07-23 Apparatus and method for obtaining transepithelial specimen of a body surface using a non-lacerating technique

Country Status (10)

Country Link
US (1) US6258044B1 (en)
EP (1) EP1098595B1 (en)
CN (1) CN1325287A (en)
AT (1) ATE487423T1 (en)
AU (1) AU5223799A (en)
CA (1) CA2355661C (en)
DE (1) DE69942935D1 (en)
ES (1) ES2358783T3 (en)
IL (1) IL141739A (en)
WO (1) WO2000004833A1 (en)

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US6623440B1 (en) * 1999-11-22 2003-09-23 Leonard Weldon Topical anesthetic applicator and method of use
CA2390794C (en) * 1999-12-03 2010-04-27 University Of Leeds Fixation technology
FR2809611B1 (en) * 2000-05-30 2002-12-20 Bernard Letellier DEVICE FOR THE CYTOLOGICAL SAMPLING OF EXOCOL AND ENDOCOL
WO2002011619A1 (en) * 2000-08-04 2002-02-14 Olympus Optical Co., Ltd. Sampler, sampling method, and substance transplanting method
AU2001294997A1 (en) * 2000-08-14 2002-03-13 Oralscan Laboratories, Inc. Detection of epithelial dysplasia
US6494845B2 (en) * 2001-05-04 2002-12-17 Oralscan Laboratories, Inc. Retractable brush for use with endoscope for brush biopsy
DE10232589A1 (en) * 2002-07-18 2004-01-29 Geka Brush Gmbh Mascara brush
FR2846221B1 (en) * 2002-10-28 2005-07-15 Oreal DEVICE FOR CARRYING OUT A SAMPLING OF DRY MATERIAL
US7776042B2 (en) * 2002-12-03 2010-08-17 Trans1 Inc. Methods and apparatus for provision of therapy to adjacent motion segments
US20040137551A1 (en) * 2003-01-13 2004-07-15 Markovic Nenad S. Cervical acid phosphatase - papanicolaou (CAP-PAP) test kit, method and accesories, processes for producing and using the same
US7226457B2 (en) * 2003-02-19 2007-06-05 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Epidermal sampling apparatus and method
US7087063B2 (en) 2003-02-19 2006-08-08 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Abrasion device and method
US20040260201A1 (en) * 2003-06-23 2004-12-23 Mueller Richard L. Cytology brush with releasable end portion
EP1691848B1 (en) 2003-10-23 2012-08-22 TRANS1, Inc. Tools and tool kits for performing minimally invasive procedures on the spine
EP1747033A1 (en) * 2004-04-30 2007-01-31 Burrell E. Clawson Apparatus and methods for isolating human body areas for localized cooling
US7749173B2 (en) * 2006-06-01 2010-07-06 Daniel Larkin Apparatus for simultaneously collecting exocervical and endocervical samples
US8439847B2 (en) 2006-06-01 2013-05-14 Daniel Larkin Method and apparatus for simultaneously collecting exocervical and endocervical samples
US8323211B2 (en) * 2006-06-01 2012-12-04 Daniel Larkin Sexually transmitted infection sampling device
AU2008275983B2 (en) 2007-07-17 2014-07-31 Histologics Llc Frictional trans-epithelial tissue disruption and collection apparatus and method of inducing and/or augmenting an immune response
US8795197B2 (en) 2007-07-17 2014-08-05 Histologics, LLC Frictional trans-epithelial tissue disruption collection apparatus and method of inducing an immune response
US8152739B1 (en) 2007-09-19 2012-04-10 Christine A. McCully Adjustable dual-brush cervical cytology collection device
US20100111398A1 (en) * 2008-10-31 2010-05-06 Texas Instruments Incorporated Method and system for detection of oral sub-mucous fibrosis using microscopic image analysis of oral biopsy samples
US8348856B1 (en) 2008-12-16 2013-01-08 Zanetta Malanowska-Stega Simultaneous multiple method out-patient uterus biopsy device and method
US9044213B1 (en) 2010-03-26 2015-06-02 Histologics, LLC Frictional tissue sampling and collection method and device
CN102138810B (en) * 2010-12-24 2016-09-07 江苏世泰实验器材有限公司 The method manufacturing quantitative biological sampling flocking swab
CN102087172B (en) * 2010-12-24 2016-09-07 江苏世泰实验器材有限公司 Quantitative biological sampling flocking swab
CN203710054U (en) * 2011-03-14 2014-07-16 医疗资源共享有限公司 Equipment for obtaining sample from epithelial tissues and disposable kit for diagnosing cervical sampling
GB201201645D0 (en) * 2012-01-31 2012-03-14 Ge Healthcare Ltd Improvements in and relating to biological sample collection
JP6159743B2 (en) * 2012-03-08 2017-07-05 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． Instrument for determining tissue characteristics
US10201332B1 (en) 2012-12-03 2019-02-12 Healoe Llc Device and method of orienting a biopsy device on epithelial tissue
US9039637B2 (en) * 2013-03-13 2015-05-26 Cook Medical Technologies Llc Flexible cytology coil
US9913728B2 (en) 2013-03-14 2018-03-13 Quandary Medical, Llc Spinal implants and implantation system
JP5686853B2 (en) * 2013-06-13 2015-03-18 デンカ生研株式会社 Swab for collecting biological specimen, method for producing the swab, and kit using the swab
EP3669747B1 (en) 2014-05-02 2022-03-30 United States Endoscopy Group, Inc. Cleaning device for an endoscopic device
USD780919S1 (en) * 2015-06-19 2017-03-07 Nipro Corporation Cell collection device
USD809140S1 (en) * 2015-06-19 2018-01-30 Nipro Corporation Cell collection device
US11013466B2 (en) 2016-01-28 2021-05-25 Healoe, Llc Device and method to control and manipulate a catheter
WO2018107175A1 (en) 2016-12-09 2018-06-14 Malanowska Stega Zanetta Brush biopsy device, kit and method
US11528988B2 (en) * 2017-11-14 2022-12-20 Georgia Tech Research Corporation Separation systems, devices and methods
US20200289098A1 (en) * 2019-03-15 2020-09-17 Orig3N, Inc. Dna collection device
USD931621S1 (en) * 2019-10-28 2021-09-28 Brushtech, Inc. Grill brush with coil spring
USD936370S1 (en) * 2019-10-28 2021-11-23 Brushtech, Inc. Grill brush with coil springs
USD931620S1 (en) * 2019-10-28 2021-09-28 Brushtech, Inc. Grill brush with coil springs

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Also Published As

Publication number Publication date
CA2355661C (en) 2006-04-11
EP1098595A4 (en) 2004-12-15
WO2000004833A1 (en) 2000-02-03
ES2358783T3 (en) 2011-05-13
WO2000004833A9 (en) 2000-05-18
EP1098595A1 (en) 2001-05-16
DE69942935D1 (en) 2010-12-23
IL141739A (en) 2006-06-11
AU5223799A (en) 2000-02-14
US6258044B1 (en) 2001-07-10
CN1325287A (en) 2001-12-05
EP1098595B1 (en) 2010-11-10
ATE487423T1 (en) 2010-11-15

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