CA2356623A1 - Systems and methods for optical examination of samples - Google Patents
Systems and methods for optical examination of samples Download PDFInfo
- Publication number
- CA2356623A1 CA2356623A1 CA002356623A CA2356623A CA2356623A1 CA 2356623 A1 CA2356623 A1 CA 2356623A1 CA 002356623 A CA002356623 A CA 002356623A CA 2356623 A CA2356623 A CA 2356623A CA 2356623 A1 CA2356623 A1 CA 2356623A1
- Authority
- CA
- Canada
- Prior art keywords
- systems
- methods
- sample
- certain embodiments
- samples
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0068—Confocal scanning
Abstract
The present invention relates to systems and methods for examining a sample using a substantially monostatic, substantially confocal optical system comprising transmitting optics that focus an illuminating Light upon the sample and receiving optics that collect light emitted from the sample following illumination thereof. In certain embodiments, the receiving optics may be arranged circumferentially around the light path traversed by the illuminating light. In certain embodiments, video apparatus may be included to produce images or to align the system in proximity to the target tissue. The systems and methods of the present invention may be directed towards the examination of a body tissue to provide a medical diagnosis.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11376198P | 1998-12-23 | 1998-12-23 | |
US60/113,761 | 1998-12-23 | ||
PCT/US1999/031001 WO2000037917A2 (en) | 1998-12-23 | 1999-12-22 | Systems and methods for optical examination of samples |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2356623A1 true CA2356623A1 (en) | 2000-06-29 |
CA2356623C CA2356623C (en) | 2005-10-18 |
Family
ID=22351348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002356623A Expired - Fee Related CA2356623C (en) | 1998-12-23 | 1999-12-22 | Systems and methods for optical examination of samples |
Country Status (6)
Country | Link |
---|---|
US (6) | US6411838B1 (en) |
EP (1) | EP1161178A2 (en) |
JP (1) | JP2002533142A (en) |
AU (1) | AU759282B2 (en) |
CA (1) | CA2356623C (en) |
WO (1) | WO2000037917A2 (en) |
Families Citing this family (192)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010041843A1 (en) * | 1999-02-02 | 2001-11-15 | Mark Modell | Spectral volume microprobe arrays |
US6826422B1 (en) * | 1997-01-13 | 2004-11-30 | Medispectra, Inc. | Spectral volume microprobe arrays |
US6411838B1 (en) | 1998-12-23 | 2002-06-25 | Medispectra, Inc. | Systems and methods for optical examination of samples |
JP2000275757A (en) * | 1999-03-24 | 2000-10-06 | Fuji Photo Film Co Ltd | Method and device for evaluating image |
US7299080B2 (en) * | 1999-10-08 | 2007-11-20 | Sensys Medical, Inc. | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
EP1178311A4 (en) * | 1999-05-10 | 2003-04-09 | Tomoya Sato | Method and apparatus for determining the type and/or condition of disease and method and apparatus for screening drug |
US7280866B1 (en) * | 1999-10-06 | 2007-10-09 | National Research Council Of Canada | Non-invasive screening of skin diseases by visible/near-infrared spectroscopy |
US20020007122A1 (en) * | 1999-12-15 | 2002-01-17 | Howard Kaufman | Methods of diagnosing disease |
MXPA02006660A (en) * | 2000-01-07 | 2002-12-13 | Transform Pharmaceuticals Inc | Highthroughput formation, identification, and analysis of diverse solidforms. |
US20070021929A1 (en) * | 2000-01-07 | 2007-01-25 | Transform Pharmaceuticals, Inc. | Computing methods for control of high-throughput experimental processing, digital analysis, and re-arraying comparative samples in computer-designed arrays |
US20050095696A9 (en) * | 2000-01-07 | 2005-05-05 | Lemmo Anthony V. | Apparatus and method for high-throughput preparation and characterization of compositions |
US20050089923A9 (en) * | 2000-01-07 | 2005-04-28 | Levinson Douglas A. | Method and system for planning, performing, and assessing high-throughput screening of multicomponent chemical compositions and solid forms of compounds |
US20070020662A1 (en) * | 2000-01-07 | 2007-01-25 | Transform Pharmaceuticals, Inc. | Computerized control of high-throughput experimental processing and digital analysis of comparative samples for a compound of interest |
US20050118637A9 (en) * | 2000-01-07 | 2005-06-02 | Levinson Douglas A. | Method and system for planning, performing, and assessing high-throughput screening of multicomponent chemical compositions and solid forms of compounds |
US7108970B2 (en) * | 2000-01-07 | 2006-09-19 | Transform Pharmaceuticals, Inc. | Rapid identification of conditions, compounds, or compositions that inhibit, prevent, induce, modify, or reverse transitions of physical state |
US6977723B2 (en) * | 2000-01-07 | 2005-12-20 | Transform Pharmaceuticals, Inc. | Apparatus and method for high-throughput preparation and spectroscopic classification and characterization of compositions |
GB0008563D0 (en) * | 2000-04-07 | 2000-05-24 | Cambridge Discovery Chemistry | Investigating different physical and/or chemical forms of materials |
US7519406B2 (en) * | 2004-04-28 | 2009-04-14 | Sensys Medical, Inc. | Noninvasive analyzer sample probe interface method and apparatus |
US20060211931A1 (en) * | 2000-05-02 | 2006-09-21 | Blank Thomas B | Noninvasive analyzer sample probe interface method and apparatus |
US7606608B2 (en) * | 2000-05-02 | 2009-10-20 | Sensys Medical, Inc. | Optical sampling interface system for in-vivo measurement of tissue |
US6530882B1 (en) * | 2000-06-30 | 2003-03-11 | Inner Vision Imaging, L.L.C. | Endoscope having microscopic and macroscopic magnification |
EP1304955B1 (en) * | 2000-07-13 | 2008-12-17 | Virginia Commonwealth University | Use of ultraviolet, near-ultraviolet and near infrared resonance raman spectroscopy and fluorescence spectroscopy for tissue interrogation of shock states, critical illnesses, and other disease states |
US20020121443A1 (en) * | 2000-11-13 | 2002-09-05 | Genoptix | Methods for the combined electrical and optical identification, characterization and/or sorting of particles |
US20020123112A1 (en) * | 2000-11-13 | 2002-09-05 | Genoptix | Methods for increasing detection sensitivity in optical dielectric sorting systems |
US6936811B2 (en) * | 2000-11-13 | 2005-08-30 | Genoptix, Inc. | Method for separating micro-particles |
US20030007894A1 (en) * | 2001-04-27 | 2003-01-09 | Genoptix | Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles |
US20020160470A1 (en) * | 2000-11-13 | 2002-10-31 | Genoptix | Methods and apparatus for generating and utilizing linear moving optical gradients |
US6839661B2 (en) * | 2000-12-15 | 2005-01-04 | Medispectra, Inc. | System for normalizing spectra |
US6783499B2 (en) * | 2000-12-18 | 2004-08-31 | Biosense, Inc. | Anchoring mechanism for implantable telemetric medical sensor |
US6636769B2 (en) | 2000-12-18 | 2003-10-21 | Biosense, Inc. | Telemetric medical system and method |
US6638231B2 (en) | 2000-12-18 | 2003-10-28 | Biosense, Inc. | Implantable telemetric medical sensor and method |
US6652464B2 (en) | 2000-12-18 | 2003-11-25 | Biosense, Inc. | Intracardiac pressure monitoring method |
US20060129329A1 (en) * | 2001-04-09 | 2006-06-15 | Kobylecki Ryszard J | Investigating different physical and/or chemical forms of materials |
US20030194755A1 (en) * | 2001-04-27 | 2003-10-16 | Genoptix, Inc. | Early detection of apoptotic events and apoptosis using optophoretic analysis |
US20040023310A1 (en) * | 2001-04-27 | 2004-02-05 | Genoptix, Inc | Quantitative determination of protein kinase C activation using optophoretic analysis |
US20040009540A1 (en) * | 2001-04-27 | 2004-01-15 | Genoptix, Inc | Detection and evaluation of cancer cells using optophoretic analysis |
US20030124516A1 (en) * | 2001-04-27 | 2003-07-03 | Genoptix, Inc. | Method of using optical interrogation to determine a biological property of a cell or population of cells |
US7831442B1 (en) | 2001-05-16 | 2010-11-09 | Perot Systems Corporation | System and method for minimizing edits for medical insurance claims processing |
US7822621B1 (en) | 2001-05-16 | 2010-10-26 | Perot Systems Corporation | Method of and system for populating knowledge bases using rule based systems and object-oriented software |
US7808633B2 (en) * | 2007-02-14 | 2010-10-05 | Chemimage Corporation | Spectroscopic system and method for predicting outcome of disease |
US7956996B2 (en) * | 2007-02-14 | 2011-06-07 | Chemimage Corporation | Distinguishing between invasive ductal carcinoma and invasive lobular carcinoma using raman molecular imaging |
US20030065477A1 (en) * | 2001-08-30 | 2003-04-03 | Opdyke John D. | Two-sample permutation tests |
WO2003023409A2 (en) * | 2001-09-07 | 2003-03-20 | Transform Pharmaceuticals, Inc. | Apparatus and method for high-throughput preparation and characterization of compositions |
JP3944383B2 (en) * | 2001-11-16 | 2007-07-11 | 株式会社日立製作所 | Cardiac magnetic field measuring device |
FI113497B (en) * | 2002-02-28 | 2004-04-30 | Vaisala Oyj | light Radar |
US20050187439A1 (en) * | 2003-03-07 | 2005-08-25 | Blank Thomas B. | Sampling interface system for in-vivo estimation of tissue analyte concentration |
US8718738B2 (en) * | 2002-03-08 | 2014-05-06 | Glt Acquisition Corp. | Method and apparatus for coupling a sample probe with a sample site |
US20050054908A1 (en) * | 2003-03-07 | 2005-03-10 | Blank Thomas B. | Photostimulation method and apparatus in combination with glucose determination |
US20070149868A1 (en) * | 2002-03-08 | 2007-06-28 | Blank Thomas B | Method and Apparatus for Photostimulation Enhanced Analyte Property Estimation |
US7697966B2 (en) * | 2002-03-08 | 2010-04-13 | Sensys Medical, Inc. | Noninvasive targeting system method and apparatus |
US7440786B2 (en) * | 2002-03-08 | 2008-10-21 | Sensys Medical, Inc. | Method and apparatus for presentation of noninvasive glucose concentration information |
EP1499231A4 (en) * | 2002-03-08 | 2007-09-26 | Sensys Medical Inc | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US8504128B2 (en) * | 2002-03-08 | 2013-08-06 | Glt Acquisition Corp. | Method and apparatus for coupling a channeled sample probe to tissue |
US8131332B2 (en) * | 2002-04-04 | 2012-03-06 | Veralight, Inc. | Determination of a measure of a glycation end-product or disease state using tissue fluorescence of various sites |
US7725144B2 (en) * | 2002-04-04 | 2010-05-25 | Veralight, Inc. | Determination of disease state using raman spectroscopy of tissue |
US20040033539A1 (en) * | 2002-05-01 | 2004-02-19 | Genoptix, Inc | Method of using optical interrogation to determine a biological property of a cell or population of cells |
US20030211461A1 (en) * | 2002-05-01 | 2003-11-13 | Genoptix, Inc | Optophoretic detection of durgs exhibiting inhibitory effect on Bcr-Abl positive tumor cells |
US7136518B2 (en) * | 2003-04-18 | 2006-11-14 | Medispectra, Inc. | Methods and apparatus for displaying diagnostic data |
US7459696B2 (en) * | 2003-04-18 | 2008-12-02 | Schomacker Kevin T | Methods and apparatus for calibrating spectral data |
US20040208385A1 (en) * | 2003-04-18 | 2004-10-21 | Medispectra, Inc. | Methods and apparatus for visually enhancing images |
US7469160B2 (en) * | 2003-04-18 | 2008-12-23 | Banks Perry S | Methods and apparatus for evaluating image focus |
US6933154B2 (en) * | 2002-07-09 | 2005-08-23 | Medispectra, Inc. | Optimal windows for obtaining optical data for characterization of tissue samples |
US7309867B2 (en) * | 2003-04-18 | 2007-12-18 | Medispectra, Inc. | Methods and apparatus for characterization of tissue samples |
US6818903B2 (en) * | 2002-07-09 | 2004-11-16 | Medispectra, Inc. | Method and apparatus for identifying spectral artifacts |
US6768918B2 (en) | 2002-07-10 | 2004-07-27 | Medispectra, Inc. | Fluorescent fiberoptic probe for tissue health discrimination and method of use thereof |
US7373198B2 (en) * | 2002-07-12 | 2008-05-13 | Bionova Technologies Inc. | Method and apparatus for the estimation of anesthetic depth using wavelet analysis of the electroencephalogram |
US7060075B2 (en) * | 2002-07-18 | 2006-06-13 | Biosense, Inc. | Distal targeting of locking screws in intramedullary nails |
US6925322B2 (en) * | 2002-07-25 | 2005-08-02 | Biophan Technologies, Inc. | Optical MRI catheter system |
US20040064053A1 (en) * | 2002-09-30 | 2004-04-01 | Chang Sung K. | Diagnostic fluorescence and reflectance |
US20040121307A1 (en) * | 2002-12-19 | 2004-06-24 | Genoptix, Inc | Early detection of cellular differentiation using optophoresis |
US20040121474A1 (en) * | 2002-12-19 | 2004-06-24 | Genoptix, Inc | Detection and evaluation of chemically-mediated and ligand-mediated t-cell activation using optophoretic analysis |
US7252659B2 (en) * | 2003-02-07 | 2007-08-07 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Implanted surgical drain with sensing and transmitting elements for monitoring internal tissue condition |
JP4041421B2 (en) * | 2003-03-25 | 2008-01-30 | 独立行政法人理化学研究所 | Raman probe and Raman scattering measuring apparatus using the same |
US7184626B1 (en) * | 2003-04-07 | 2007-02-27 | Luxtera, Inc | Wafer-level testing of optical and optoelectronic chips |
US20050119587A1 (en) * | 2003-07-01 | 2005-06-02 | University Of Michigan | Method and apparatus for evaluating connective tissue conditions |
JP2007524833A (en) | 2003-07-01 | 2007-08-30 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | Method and apparatus for diagnosing bone tissue condition |
AU2004269406B2 (en) * | 2003-08-28 | 2010-12-16 | Progenity, Inc. | Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network |
US20070234300A1 (en) * | 2003-09-18 | 2007-10-04 | Leake David W | Method and Apparatus for Performing State-Table Driven Regression Testing |
US7970452B2 (en) * | 2003-09-30 | 2011-06-28 | Hologic, Inc. | Open architecture imaging apparatus and coil system for magnetic resonance imaging |
US20080077005A1 (en) * | 2004-08-12 | 2008-03-27 | Piron Cameron A | System and Method for Multimodality Breast Imaging |
US7908690B2 (en) * | 2003-09-30 | 2011-03-22 | Sentinelle Medical, Inc. | Supine patient support for medical imaging |
US7379769B2 (en) | 2003-09-30 | 2008-05-27 | Sunnybrook Health Sciences Center | Hybrid imaging method to monitor medical device delivery and patient support for use in the method |
DE10355150B4 (en) * | 2003-11-26 | 2021-01-14 | Leica Microsystems Cms Gmbh | Method and system for the analysis of co-localizations |
US8326404B2 (en) * | 2003-11-28 | 2012-12-04 | British Columbia Cancer Agency Branch | Multimodal detection of tissue abnormalities based on raman and background fluorescence spectroscopy |
JP4509578B2 (en) | 2004-01-09 | 2010-07-21 | 浜松ホトニクス株式会社 | Laser processing method and laser processing apparatus |
JP4601965B2 (en) | 2004-01-09 | 2010-12-22 | 浜松ホトニクス株式会社 | Laser processing method and laser processing apparatus |
JP4598407B2 (en) * | 2004-01-09 | 2010-12-15 | 浜松ホトニクス株式会社 | Laser processing method and laser processing apparatus |
US20050215876A1 (en) * | 2004-03-25 | 2005-09-29 | Eastman Kodak Company | Method and system for automatic image adjustment for in vivo image diagnosis |
US20080033275A1 (en) * | 2004-04-28 | 2008-02-07 | Blank Thomas B | Method and Apparatus for Sample Probe Movement Control |
US8868147B2 (en) * | 2004-04-28 | 2014-10-21 | Glt Acquisition Corp. | Method and apparatus for controlling positioning of a noninvasive analyzer sample probe |
US7697576B2 (en) * | 2004-05-05 | 2010-04-13 | Chem Image Corporation | Cytological analysis by raman spectroscopic imaging |
US7316904B1 (en) | 2004-06-30 | 2008-01-08 | Chromodynamics, Inc. | Automated pap screening using optical detection of HPV with or without multispectral imaging |
WO2006019991A2 (en) * | 2004-07-15 | 2006-02-23 | Cheminage Corporation | Method and apparatus for multimodal detection |
US7254501B1 (en) * | 2004-12-10 | 2007-08-07 | Ahura Corporation | Spectrum searching method that uses non-chemical qualities of the measurement |
US8929688B2 (en) * | 2004-10-01 | 2015-01-06 | University Of Washington | Remapping methods to reduce distortions in images |
US7298938B2 (en) * | 2004-10-01 | 2007-11-20 | University Of Washington | Configuration memory for a scanning beam device |
JP2006145810A (en) * | 2004-11-19 | 2006-06-08 | Canon Inc | Automatic focusing apparatus, laser beam machining apparatus and laser beam cutter |
JP5367267B2 (en) * | 2004-11-26 | 2013-12-11 | ロレアル | How to observe biological tissue, especially human skin |
FR2878424B1 (en) * | 2004-11-26 | 2008-02-01 | Oreal | METHOD FOR OBSERVING A BIOLOGICAL TISSUE, IN PARTICULAR HUMAN SKIN |
US7854705B2 (en) * | 2004-12-16 | 2010-12-21 | Olga Pawluczyk | Ex vivo verification of biopsy tissue samples |
US8244332B2 (en) * | 2004-12-22 | 2012-08-14 | Siemens Medical Solutions Usa, Inc. | Three-dimensional breast anatomy imaging system |
US7159782B2 (en) * | 2004-12-23 | 2007-01-09 | University Of Washington | Methods of driving a scanning beam device to achieve high frame rates |
US7784697B2 (en) | 2004-12-23 | 2010-08-31 | University Of Washington | Methods of driving a scanning beam device to achieve high frame rates |
US7524445B2 (en) * | 2004-12-31 | 2009-04-28 | Boston Scientific Scimed, Inc. | Method for making ePTFE and structure containing such ePTFE, such as a vascular graft |
WO2006076772A1 (en) * | 2005-01-21 | 2006-07-27 | Optiscan Pty Ltd | Fibre bundle confocal endomicroscope |
US7189961B2 (en) * | 2005-02-23 | 2007-03-13 | University Of Washington | Scanning beam device with detector assembly |
US20060217602A1 (en) * | 2005-03-04 | 2006-09-28 | Alan Abul-Haj | Method and apparatus for noninvasive targeting |
US7219038B2 (en) * | 2005-03-22 | 2007-05-15 | College Of William And Mary | Automatic peak identification method |
US20060226231A1 (en) * | 2005-03-29 | 2006-10-12 | University Of Washington | Methods and systems for creating sequential color images |
US7627059B2 (en) * | 2005-04-05 | 2009-12-01 | Samsung Electronics Co., Ltd. | Method of robust timing detection and carrier frequency offset estimation for OFDM systems |
US7616699B2 (en) * | 2005-04-12 | 2009-11-10 | Samsung Electronics Co., Ltd. | Method of soft bit metric calculation with direct matrix inversion MIMO detection |
EP1902301A4 (en) | 2005-07-14 | 2010-09-22 | Chemimage Corp | Time and space resolved standoff hyperspectral ied explosives lidar detector |
US7679740B2 (en) * | 2005-07-14 | 2010-03-16 | Chemimage Corporation | Method and apparatus for multimodal detection |
US8582089B2 (en) * | 2006-06-09 | 2013-11-12 | Chemimage Corporation | System and method for combined raman, SWIR and LIBS detection |
US7395967B2 (en) * | 2005-07-21 | 2008-07-08 | University Of Washington | Methods and systems for counterbalancing a scanning beam device |
US7312879B2 (en) * | 2005-08-23 | 2007-12-25 | University Of Washington | Distance determination in a scanned beam image capture device |
CN102007513A (en) * | 2005-08-26 | 2011-04-06 | 卡姆特有限公司 | Device and method for inspecting an object |
US7729749B2 (en) * | 2005-09-01 | 2010-06-01 | The Regents Of The University Of Michigan | Method and apparatus for evaluating connective tissue conditions |
US20070178067A1 (en) * | 2005-11-09 | 2007-08-02 | John Maier | System and method for cytological analysis by raman spectroscopic imaging |
WO2007056568A2 (en) * | 2005-11-09 | 2007-05-18 | Chemimage Corporation | Spectral imaging of biofilms |
US20070161876A1 (en) * | 2005-11-18 | 2007-07-12 | Spectrx, Inc. | Method and apparatus for rapid detection and diagnosis of tissue abnormalities |
US7751506B2 (en) | 2005-12-01 | 2010-07-06 | Samsung Electronics Co., Ltd. | Method for the soft bit metric calculation with linear MIMO detection for LDPC codes |
US8368880B2 (en) * | 2005-12-23 | 2013-02-05 | Chemimage Corporation | Chemical imaging explosives (CHIMED) optical sensor using SWIR |
US7692776B2 (en) * | 2005-12-23 | 2010-04-06 | Chem Image Corporation | Chemical imaging explosives (CHIMED) optical sensor |
EP1971838A2 (en) * | 2006-01-05 | 2008-09-24 | Chemimage Corporation | System and method for classifying cells and the pharmaceutical treatment of such cells using raman spectroscopy |
US8379197B2 (en) * | 2006-01-05 | 2013-02-19 | Chemimage Corporation | Spectroscopic systems and methods for classifying and pharmaceutically treating cells |
US7996173B2 (en) | 2006-07-31 | 2011-08-09 | Visualant, Inc. | Method, apparatus, and article to facilitate distributed evaluation of objects using electromagnetic energy |
JP2009545746A (en) | 2006-07-31 | 2009-12-24 | ヴィジュアラント,インコーポレイテッド | System and method for evaluating objects using electromagnetic energy |
US8081304B2 (en) * | 2006-07-31 | 2011-12-20 | Visualant, Inc. | Method, apparatus, and article to facilitate evaluation of objects using electromagnetic energy |
US7680373B2 (en) * | 2006-09-13 | 2010-03-16 | University Of Washington | Temperature adjustment in scanning beam devices |
US7447415B2 (en) * | 2006-12-15 | 2008-11-04 | University Of Washington | Attaching optical fibers to actuator tubes with beads acting as spacers and adhesives |
US7738762B2 (en) * | 2006-12-15 | 2010-06-15 | University Of Washington | Attaching optical fibers to actuator tubes with beads acting as spacers and adhesives |
US8305432B2 (en) * | 2007-01-10 | 2012-11-06 | University Of Washington | Scanning beam device calibration |
US7990532B2 (en) | 2007-01-16 | 2011-08-02 | Chemimage Corporation | Method and apparatus for multimodal detection |
US8155417B2 (en) | 2007-03-27 | 2012-04-10 | Hologic, Inc. | Post-acquisition adaptive reconstruction of MRI data |
US7583872B2 (en) * | 2007-04-05 | 2009-09-01 | University Of Washington | Compact scanning fiber device |
US7608842B2 (en) * | 2007-04-26 | 2009-10-27 | University Of Washington | Driving scanning fiber devices with variable frequency drive signals |
US20080281159A1 (en) * | 2007-05-08 | 2008-11-13 | University Of Washington | Coordinating image acquisition among multiple endoscopes |
US20080281207A1 (en) * | 2007-05-08 | 2008-11-13 | University Of Washington | Image acquisition through filtering in multiple endoscope systems |
US8212884B2 (en) * | 2007-05-22 | 2012-07-03 | University Of Washington | Scanning beam device having different image acquisition modes |
US8437587B2 (en) * | 2007-07-25 | 2013-05-07 | University Of Washington | Actuating an optical fiber with a piezoelectric actuator and detecting voltages generated by the piezoelectric actuator |
GB2451442B (en) * | 2007-07-30 | 2013-03-06 | Lein Applied Diagnostics Ltd | Optical measurement apparatus and method therefor |
US20090036759A1 (en) * | 2007-08-01 | 2009-02-05 | Ault Timothy E | Collapsible noninvasive analyzer method and apparatus |
WO2009021178A1 (en) * | 2007-08-08 | 2009-02-12 | Chemimage Corporation | Raman difference spectra based disease classification |
US7522813B1 (en) * | 2007-10-04 | 2009-04-21 | University Of Washington | Reducing distortion in scanning fiber devices |
US8553337B2 (en) * | 2007-11-12 | 2013-10-08 | Cornell University | Multi-path, multi-magnification, non-confocal fluorescence emission endoscopy apparatus and methods |
US8290569B2 (en) * | 2007-11-23 | 2012-10-16 | Hologic, Inc. | Open architecture tabletop patient support and coil system |
US8411922B2 (en) * | 2007-11-30 | 2013-04-02 | University Of Washington | Reducing noise in images acquired with a scanning beam device |
US9581723B2 (en) | 2008-04-10 | 2017-02-28 | Schlumberger Technology Corporation | Method for characterizing a geological formation traversed by a borehole |
US8725477B2 (en) * | 2008-04-10 | 2014-05-13 | Schlumberger Technology Corporation | Method to generate numerical pseudocores using borehole images, digital rock samples, and multi-point statistics |
US8611975B2 (en) * | 2009-10-28 | 2013-12-17 | Gluco Vista, Inc. | Apparatus and method for non-invasive measurement of a substance within a body |
US20110004080A1 (en) * | 2008-04-11 | 2011-01-06 | Glucovista, Llc | Method for non-invasive analysis of a substance concentration within a body |
CA2891990C (en) | 2008-05-20 | 2022-07-26 | Ralph Sebastian Dacosta | Device and method for fluorescence-based imaging and monitoring |
US8954133B1 (en) | 2008-08-08 | 2015-02-10 | The United States Of America As Represented By The Department Of Veterans Affairs | Spectroscopic detection of brain damage |
US8077386B2 (en) | 2008-10-22 | 2011-12-13 | Microbrightfield, Inc. | Movable objective lens assembly for an optical microscope and optical microscopes having such an assembly |
CA2758118C (en) | 2009-04-07 | 2019-05-21 | Catholic Healthcare West | Uterine electrical stimulation system and method |
US8311788B2 (en) * | 2009-07-01 | 2012-11-13 | Schlumberger Technology Corporation | Method to quantify discrete pore shapes, volumes, and surface areas using confocal profilometry |
US20110004447A1 (en) * | 2009-07-01 | 2011-01-06 | Schlumberger Technology Corporation | Method to build 3D digital models of porous media using transmitted laser scanning confocal mircoscopy and multi-point statistics |
US8747331B2 (en) * | 2009-06-23 | 2014-06-10 | Hologic, Inc. | Variable angle guide holder for a biopsy guide plug |
EP2461733A1 (en) * | 2009-08-07 | 2012-06-13 | Dignity Health | Cervical, fetal-membrane, and amniotic examination and assessment device and method |
US9103714B2 (en) * | 2009-10-06 | 2015-08-11 | Chemimage Corporation | System and methods for explosives detection using SWIR |
US8903466B2 (en) | 2009-10-28 | 2014-12-02 | Glucovista Inc. | Apparatus and method for non-invasive measurement of a substance within a body |
WO2011063517A1 (en) * | 2009-11-27 | 2011-06-03 | Sentinelle Medical Inc. | Systems and methods for tracking positions between imaging modalities and transforming a displayed three-dimensional image corresponding to a position and orientation of a probe |
US8988680B2 (en) | 2010-04-30 | 2015-03-24 | Chemimage Technologies Llc | Dual polarization with liquid crystal tunable filters |
US7884933B1 (en) | 2010-05-05 | 2011-02-08 | Revolutionary Business Concepts, Inc. | Apparatus and method for determining analyte concentrations |
US9151769B2 (en) * | 2010-07-02 | 2015-10-06 | Idexx Laboratories, Inc. | Automated calibration method and system for a diagnostic analyzer |
JP5604248B2 (en) * | 2010-09-28 | 2014-10-08 | 富士フイルム株式会社 | Endoscopic image display device |
CA3023152C (en) | 2010-10-27 | 2020-01-07 | Dignity Health | Uterine electrical stimulation system and method |
US9872983B2 (en) | 2010-10-27 | 2018-01-23 | Dignity Health | Uterine electrical stimulation system and method |
US9332926B2 (en) | 2010-11-25 | 2016-05-10 | Invivo Corporation | MRI imaging probe |
KR101691156B1 (en) | 2010-12-14 | 2016-12-30 | 삼성전자주식회사 | Optical system having integrated illumination and imaging systems and 3D image acquisition apparatus including the optical system |
AU2012208912B2 (en) * | 2011-01-18 | 2016-03-03 | Holland Bloorview Kids Rehabilitation Hospital | Method and device for swallowing impairment detection |
WO2013119824A1 (en) | 2012-02-10 | 2013-08-15 | Visualant, Inc. | Systems, methods and articles related to machine-readable indicia and symbols |
US20130310680A1 (en) | 2012-05-21 | 2013-11-21 | The Regents Of The University Of Colorado, A Body Corporate | Three-dimensional optical imaging and therapy of prostate cancer |
US9814448B2 (en) | 2012-05-21 | 2017-11-14 | Precision Biopsy, Inc. | Three-dimensional optical imaging and therapy of prostate cancer |
US9076246B2 (en) | 2012-08-09 | 2015-07-07 | Hologic, Inc. | System and method of overlaying images of different modalities |
JP2014106116A (en) * | 2012-11-28 | 2014-06-09 | Shimadzu Corp | Plastic determination device |
US9316581B2 (en) | 2013-02-04 | 2016-04-19 | Visualant, Inc. | Method, apparatus, and article to facilitate evaluation of substances using electromagnetic energy |
DE112014000683B4 (en) * | 2013-02-05 | 2023-10-05 | Paul Fournier | Fiber optic probe for long distance spectroscopy |
US9041920B2 (en) | 2013-02-21 | 2015-05-26 | Visualant, Inc. | Device for evaluation of fluids using electromagnetic energy |
US9664610B2 (en) | 2013-03-12 | 2017-05-30 | Visualant, Inc. | Systems for fluid analysis using electromagnetic energy that is reflected a number of times through a fluid contained within a reflective chamber |
AU2014237346B2 (en) | 2013-03-15 | 2020-02-27 | Hologic, Inc. | System and method for reviewing and analyzing cytological specimens |
EP2856926A1 (en) | 2013-10-04 | 2015-04-08 | Tidi Products, LLC | Sheath for a medical or dental instrument |
JP6143386B2 (en) * | 2013-12-16 | 2017-06-07 | 日本電信電話株式会社 | End face observation device |
JP2016028229A (en) * | 2014-07-08 | 2016-02-25 | キヤノン株式会社 | Data processing apparatus, data display system having the same, sample information acquisition system, data processing method, program, and storage medium |
DK3171765T3 (en) | 2014-07-24 | 2021-11-01 | Univ Health Network | COLLECTION AND ANALYSIS OF DATA FOR DIAGNOSTIC PURPOSES |
DE102014013179A1 (en) * | 2014-09-04 | 2016-03-10 | Diehl Bgt Defence Gmbh & Co. Kg | Targeting device for a guided missile |
EP3430377A4 (en) * | 2016-03-16 | 2019-11-27 | Ohio State Innovation Foundation | System and method for the discrimination of tissues using a fast infrared cancer probe |
DE102016112010B4 (en) * | 2016-03-22 | 2021-03-04 | Jenoptik Industrial Metrology Germany Gmbh | Bore inspection device |
US20200081938A1 (en) * | 2018-09-06 | 2020-03-12 | Columbia Insurance Company | Turf playability testing |
US11328435B2 (en) * | 2020-06-08 | 2022-05-10 | KLA Corp. | Image alignment setup for specimens with intra- and inter-specimen variations using unsupervised learning and adaptive database generation methods |
US11848094B2 (en) | 2022-04-08 | 2023-12-19 | Ohio State Innovation Foundation | Multidimensional optical tissue classification and display |
Family Cites Families (249)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3013467A (en) | 1957-11-07 | 1961-12-19 | Minsky Marvin | Microscopy apparatus |
US3632865A (en) * | 1969-12-23 | 1972-01-04 | Bell Telephone Labor Inc | Predictive video encoding using measured subject velocity |
US3809072A (en) | 1971-10-07 | 1974-05-07 | Med General Inc | Sterile sheath apparatus for fiber optic illuminator with compatible lens |
IT985204B (en) * | 1972-05-26 | 1974-11-30 | Adelman Stuart Lee | IMPROVEMENT IN ENDOSCOPES AND THE LIKE |
US3890462A (en) | 1974-04-17 | 1975-06-17 | Bell Telephone Labor Inc | Speed and direction indicator for video systems |
US3963019A (en) | 1974-11-25 | 1976-06-15 | Quandt Robert S | Ocular testing method and apparatus |
US4017192A (en) | 1975-02-06 | 1977-04-12 | Neotec Corporation | Optical analysis of biomedical specimens |
US4071020A (en) * | 1976-06-03 | 1978-01-31 | Xienta, Inc. | Apparatus and methods for performing in-vivo measurements of enzyme activity |
GB1595422A (en) | 1977-04-28 | 1981-08-12 | Nat Res Dev | Scaning microscopes |
FR2430754A1 (en) | 1978-07-13 | 1980-02-08 | Groux Jean | ULTRAVIOLET ENDOSCOPE |
US4218703A (en) | 1979-03-16 | 1980-08-19 | Bell Telephone Laboratories, Incorporated | Technique for estimation of displacement and/or velocity of objects in video scenes |
US4357075A (en) | 1979-07-02 | 1982-11-02 | Hunter Thomas M | Confocal reflector system |
US4254421A (en) | 1979-12-05 | 1981-03-03 | Communications Satellite Corporation | Integrated confocal electromagnetic wave lens and feed antenna system |
DE2951459C2 (en) | 1979-12-20 | 1984-03-29 | Heimann Gmbh, 6200 Wiesbaden | Optical arrangement for a smoke detector based on the light scattering principle |
US4515165A (en) * | 1980-02-04 | 1985-05-07 | Energy Conversion Devices, Inc. | Apparatus and method for detecting tumors |
ATE23752T1 (en) | 1980-08-21 | 1986-12-15 | Oriel Scient Ltd | OPTICAL ANALYZER. |
AU556742B2 (en) | 1982-02-01 | 1986-11-20 | Sony Corporation | Digital tape jitter compensation |
US4619268A (en) | 1983-08-11 | 1986-10-28 | Vitacomm, Ltd. | Esophageal stethoscope and vital signs monitor system |
US5139025A (en) | 1983-10-14 | 1992-08-18 | Somanetics Corporation | Method and apparatus for in vivo optical spectroscopic examination |
SU1223092A1 (en) | 1984-03-11 | 1986-04-07 | Предприятие П/Я Р-6681 | Small-angle nephelometer |
SE455736B (en) | 1984-03-15 | 1988-08-01 | Sarastro Ab | PROCEDURE KIT AND MICROPHOTOMETRATION AND ADDITIONAL IMAGE COMPOSITION |
US4641352A (en) * | 1984-07-12 | 1987-02-03 | Paul Fenster | Misregistration correction |
US5179936A (en) | 1984-10-23 | 1993-01-19 | Intelligent Medical Systems, Inc. | Disposable speculum with membrane bonding ring |
US4662360A (en) | 1984-10-23 | 1987-05-05 | Intelligent Medical Systems, Inc. | Disposable speculum |
US4646722A (en) * | 1984-12-10 | 1987-03-03 | Opielab, Inc. | Protective endoscope sheath and method of installing same |
US4803049A (en) * | 1984-12-12 | 1989-02-07 | The Regents Of The University Of California | pH-sensitive optrode |
CA1279901C (en) * | 1985-03-22 | 1991-02-05 | Carter Kittrell | Catheter for laser angiosurgery |
US5693043A (en) | 1985-03-22 | 1997-12-02 | Massachusetts Institute Of Technology | Catheter for laser angiosurgery |
US5199431A (en) | 1985-03-22 | 1993-04-06 | Massachusetts Institute Of Technology | Optical needle for spectroscopic diagnosis |
US5042494A (en) | 1985-11-13 | 1991-08-27 | Alfano Robert R | Method and apparatus for detecting cancerous tissue using luminescence excitation spectra |
US4930516B1 (en) | 1985-11-13 | 1998-08-04 | Laser Diagnostic Instr Inc | Method for detecting cancerous tissue using visible native luminescence |
JPS62138819A (en) | 1985-12-13 | 1987-06-22 | Hitachi Ltd | Scanning type laser microscope |
JPS62247232A (en) | 1986-04-21 | 1987-10-28 | Agency Of Ind Science & Technol | Fluorescence measuring apparatus |
US4852955A (en) | 1986-09-16 | 1989-08-01 | Laser Precision Corporation | Microscope for use in modular FTIR spectrometer system |
US5011243A (en) | 1986-09-16 | 1991-04-30 | Laser Precision Corporation | Reflectance infrared microscope having high radiation throughput |
US4741326A (en) | 1986-10-01 | 1988-05-03 | Fujinon, Inc. | Endoscope disposable sheath |
US4891829A (en) | 1986-11-19 | 1990-01-02 | Exxon Research And Engineering Company | Method and apparatus for utilizing an electro-optic detector in a microtomography system |
NL8603108A (en) | 1986-12-08 | 1988-07-01 | Philips Nv | MICROSALE. |
US4810875A (en) | 1987-02-02 | 1989-03-07 | Wyatt Technology Corporation | Method and apparatus for examining the interior of semi-opaque objects |
CA1300369C (en) | 1987-03-24 | 1992-05-12 | Timothy P. Dabbs | Distance measuring device |
US5235457A (en) | 1987-09-24 | 1993-08-10 | Washington University | Kit for converting a standard microscope into a single aperture confocal scanning epi-illumination microscope |
US4945478A (en) | 1987-11-06 | 1990-07-31 | Center For Innovative Technology | Noninvasive medical imaging system and method for the identification and 3-D display of atherosclerosis and the like |
US4800571A (en) * | 1988-01-11 | 1989-01-24 | Tektronix, Inc. | Timing jitter measurement display |
US4844617A (en) | 1988-01-20 | 1989-07-04 | Tencor Instruments | Confocal measuring microscope with automatic focusing |
FR2626383B1 (en) | 1988-01-27 | 1991-10-25 | Commissariat Energie Atomique | EXTENDED FIELD SCAN AND DEPTH CONFOCAL OPTICAL MICROSCOPY AND DEVICES FOR CARRYING OUT THE METHOD |
US4997242A (en) | 1988-03-07 | 1991-03-05 | Medical Research Council | Achromatic scanning system |
US4934811A (en) | 1988-04-01 | 1990-06-19 | Syntex (U.S.A.) Inc. | Apparatus and method for detection of fluorescence or light scatter |
US5032720A (en) | 1988-04-21 | 1991-07-16 | White John G | Confocal imaging system |
US4877033A (en) | 1988-05-04 | 1989-10-31 | Seitz Jr H Michael | Disposable needle guide and examination sheath for transvaginal ultrasound procedures |
DE8808299U1 (en) | 1988-06-25 | 1989-07-20 | Effner Gmbh, 1000 Berlin, De | |
EP1245987B1 (en) | 1988-07-13 | 2008-01-23 | Optiscan Pty Ltd | Scanning confocal microscope |
CA1340997C (en) | 1988-07-15 | 2000-05-16 | Frampton E. Ellis Iii | Shoe with naturally contoured sole |
CA1325537C (en) | 1988-08-01 | 1993-12-28 | Timothy Peter Dabbs | Confocal microscope |
US5036853A (en) | 1988-08-26 | 1991-08-06 | Polartechnics Ltd. | Physiological probe |
US4972258A (en) | 1989-07-31 | 1990-11-20 | E. I. Du Pont De Nemours And Company | Scanning laser microscope system and methods of use |
US5101825A (en) * | 1988-10-28 | 1992-04-07 | Blackbox, Inc. | Method for noninvasive intermittent and/or continuous hemoglobin, arterial oxygen content, and hematocrit determination |
US5205291A (en) * | 1988-11-08 | 1993-04-27 | Health Research, Inc. | In vivo fluorescence photometer |
WO1990006718A1 (en) | 1988-12-21 | 1990-06-28 | Massachusetts Institute Of Technology | A method for laser induced fluorescence of tissue |
US5022757A (en) | 1989-01-23 | 1991-06-11 | Modell Mark D | Heterodyne system and method for sensing a target substance |
US4878485A (en) | 1989-02-03 | 1989-11-07 | Adair Edwin Lloyd | Rigid video endoscope with heat sterilizable sheath |
US5003979A (en) | 1989-02-21 | 1991-04-02 | University Of Virginia | System and method for the noninvasive identification and display of breast lesions and the like |
US5421337A (en) | 1989-04-14 | 1995-06-06 | Massachusetts Institute Of Technology | Spectral diagnosis of diseased tissue |
US5201318A (en) | 1989-04-24 | 1993-04-13 | Rava Richard P | Contour mapping of spectral diagnostics |
JPH0378720A (en) | 1989-08-22 | 1991-04-03 | Nikon Corp | Confocal laser scanning microscope |
US5065008A (en) | 1989-10-18 | 1991-11-12 | Fuji Photo Film Co., Ltd. | Scanning microscope and scanning mechanism for the same |
DE8912757U1 (en) | 1989-10-27 | 1989-12-07 | Fa. Carl Zeiss, 7920 Heidenheim, De | |
US4979498A (en) | 1989-10-30 | 1990-12-25 | Machida Incorporated | Video cervicoscope system |
US5034613A (en) | 1989-11-14 | 1991-07-23 | Cornell Research Foundation, Inc. | Two-photon laser microscopy |
US5257617A (en) | 1989-12-25 | 1993-11-02 | Asahi Kogaku Kogyo Kabushiki Kaisha | Sheathed endoscope and sheath therefor |
US5028802A (en) | 1990-01-11 | 1991-07-02 | Eye Research Institute Of Retina Foundation | Imaging apparatus and methods utilizing scannable microlaser source |
US5274240A (en) | 1990-01-12 | 1993-12-28 | The Regents Of The University Of California | Capillary array confocal fluorescence scanner and method |
US5091652A (en) | 1990-01-12 | 1992-02-25 | The Regents Of The University Of California | Laser excited confocal microscope fluorescence scanner and method |
EP0448931B1 (en) | 1990-01-26 | 1996-04-03 | Canon Kabushiki Kaisha | Method for measuring a specimen by the use of fluorescence light |
JPH0742401Y2 (en) | 1990-02-01 | 1995-10-04 | 株式会社町田製作所 | Endoscope cover |
JPH03101903U (en) | 1990-02-01 | 1991-10-23 | ||
US5074306A (en) | 1990-02-22 | 1991-12-24 | The General Hospital Corporation | Measurement of burn depth in skin |
EP0444689B1 (en) | 1990-03-01 | 1995-12-20 | X-Rite, Inc. | A compensation method adapted for use in color measuring apparatus |
US5083220A (en) | 1990-03-22 | 1992-01-21 | Tandem Scanning Corporation | Scanning disks for use in tandem scanning reflected light microscopes and other optical systems |
JP2613118B2 (en) | 1990-04-10 | 1997-05-21 | 富士写真フイルム株式会社 | Confocal scanning microscope |
US5048946A (en) | 1990-05-15 | 1991-09-17 | Phoenix Laser Systems, Inc. | Spectral division of reflected light in complex optical diagnostic and therapeutic systems |
EP0458601B1 (en) | 1990-05-22 | 1996-08-28 | Research Development Corporation Of Japan | Method of and apparatus for measuring spectral absorption in opaque specimens and method of and apparatus for measuring microscopic absorption distribution |
GB9014263D0 (en) | 1990-06-27 | 1990-08-15 | Dixon Arthur E | Apparatus and method for spatially- and spectrally- resolvedmeasurements |
GB9016587D0 (en) | 1990-07-27 | 1990-09-12 | Isis Innovation | Infra-red scanning microscopy |
US5324979A (en) | 1990-09-26 | 1994-06-28 | Futrex, Inc. | Method and means for generating synthetic spectra allowing quantitative measurement in near infrared measuring instruments |
US5239178A (en) | 1990-11-10 | 1993-08-24 | Carl Zeiss | Optical device with an illuminating grid and detector grid arranged confocally to an object |
US5168157A (en) | 1990-11-20 | 1992-12-01 | Fuji Photo Film Co., Ltd. | Scanning microscope with means for detecting a first and second polarized light beams along first and second optical receiving paths |
US5193525A (en) * | 1990-11-30 | 1993-03-16 | Vision Sciences | Antiglare tip in a sheath for an endoscope |
US5720293A (en) * | 1991-01-29 | 1998-02-24 | Baxter International Inc. | Diagnostic catheter with memory |
JP3103894B2 (en) * | 1991-02-06 | 2000-10-30 | ソニー株式会社 | Apparatus and method for correcting camera shake of video data |
US5261410A (en) * | 1991-02-07 | 1993-11-16 | Alfano Robert R | Method for determining if a tissue is a malignant tumor tissue, a benign tumor tissue, or a normal or benign tissue using Raman spectroscopy |
US5162641A (en) | 1991-02-19 | 1992-11-10 | Phoenix Laser Systems, Inc. | System and method for detecting, correcting and measuring depth movement of target tissue in a laser surgical system |
US5303026A (en) | 1991-02-26 | 1994-04-12 | The Regents Of The University Of California Los Alamos National Laboratory | Apparatus and method for spectroscopic analysis of scattering media |
US5260578A (en) | 1991-04-10 | 1993-11-09 | Mayo Foundation For Medical Education And Research | Confocal imaging system for visible and ultraviolet light |
DE4111903A1 (en) | 1991-04-12 | 1992-10-15 | Bayer Ag | SPECTROSCOPY-CORRECTED LIGHT-SCREEN MICROSCOPY |
US5257085A (en) | 1991-04-24 | 1993-10-26 | Kaman Aerospace Corporation | Spectrally dispersive imaging lidar system |
WO1992019930A1 (en) | 1991-04-29 | 1992-11-12 | Massachusetts Institute Of Technology | Method and apparatus for optical imaging and measurement |
CA2042075C (en) * | 1991-05-08 | 2001-01-23 | Branko Palcic | Endoscopic imaging system |
DK0540714T3 (en) * | 1991-05-24 | 1998-09-07 | British Broadcasting Corp | video Imaging |
JP2975719B2 (en) | 1991-05-29 | 1999-11-10 | オリンパス光学工業株式会社 | Confocal optics |
US5319200A (en) | 1991-06-05 | 1994-06-07 | Zeltex, Inc. | Rapid near-infrared measurement of nonhomogeneous samples |
US5201908A (en) | 1991-06-10 | 1993-04-13 | Endomedical Technologies, Inc. | Sheath for protecting endoscope from contamination |
US5313567A (en) | 1991-06-13 | 1994-05-17 | At&T Bell Laboratories | Arrangement for determining and displaying volumetric data in an imaging system |
US5237984A (en) | 1991-06-24 | 1993-08-24 | Xomed-Treace Inc. | Sheath for endoscope |
US5769792A (en) | 1991-07-03 | 1998-06-23 | Xillix Technologies Corp. | Endoscopic imaging system for diseased tissue |
US5203328A (en) * | 1991-07-17 | 1993-04-20 | Georgia Tech Research Corporation | Apparatus and methods for quantitatively measuring molecular changes in the ocular lens |
US5162941A (en) | 1991-07-23 | 1992-11-10 | The Board Of Governors Of Wayne State University | Confocal microscope |
JPH0527177A (en) | 1991-07-25 | 1993-02-05 | Fuji Photo Film Co Ltd | Scanning type microscope |
JP3082346B2 (en) | 1991-09-12 | 2000-08-28 | 株式会社ニコン | Fluorescence confocal microscope |
US5383874A (en) * | 1991-11-08 | 1995-01-24 | Ep Technologies, Inc. | Systems for identifying catheters and monitoring their use |
US5467767A (en) * | 1991-11-25 | 1995-11-21 | Alfano; Robert R. | Method for determining if tissue is malignant as opposed to non-malignant using time-resolved fluorescence spectroscopy |
JP3018687B2 (en) | 1991-12-12 | 2000-03-13 | 松下電器産業株式会社 | Scanning laser microscope |
US5253071A (en) | 1991-12-20 | 1993-10-12 | Sony Corporation Of America | Method and apparatus for stabilizing an image produced in a video camera |
US5398685A (en) | 1992-01-10 | 1995-03-21 | Wilk; Peter J. | Endoscopic diagnostic system and associated method |
US5284149A (en) | 1992-01-23 | 1994-02-08 | Dhadwal Harbans S | Method and apparatus for determining the physical characteristics of ocular tissue |
US5248876A (en) | 1992-04-21 | 1993-09-28 | International Business Machines Corporation | Tandem linear scanning confocal imaging system with focal volumes at different heights |
GB9213978D0 (en) | 1992-07-01 | 1992-08-12 | Skidmore Robert | Medical devices |
US5325846A (en) | 1992-07-27 | 1994-07-05 | Linvatec Corporation | Endoscopic draping apparatus and method |
US5609560A (en) | 1992-08-19 | 1997-03-11 | Olympus Optical Co., Ltd. | Medical operation device control system for controlling a operation devices accessed respectively by ID codes |
US5704892A (en) | 1992-09-01 | 1998-01-06 | Adair; Edwin L. | Endoscope with reusable core and disposable sheath with passageways |
US5402768A (en) | 1992-09-01 | 1995-04-04 | Adair; Edwin L. | Endoscope with reusable core and disposable sheath with passageways |
US5306902A (en) | 1992-09-01 | 1994-04-26 | International Business Machines Corporation | Confocal method and apparatus for focusing in projection lithography |
CH684556A5 (en) | 1992-09-14 | 1994-10-14 | Cerberus Ag | Optical Smoke Detector. |
US5285490A (en) * | 1992-10-22 | 1994-02-08 | Eastman Kodak Company | Imaging combination for detecting soft tissue anomalies |
US5337734A (en) | 1992-10-29 | 1994-08-16 | Advanced Polymers, Incorporated | Disposable sheath with optically transparent window formed continuously integral therewith |
US5469853A (en) | 1992-12-11 | 1995-11-28 | Tetrad Corporation | Bendable ultrasonic probe and sheath for use therewith |
US5418797A (en) | 1993-01-15 | 1995-05-23 | The United States Of America As Represented By The Secretary Of The Navy | Time gated imaging through scattering material using polarization and stimulated raman amplification |
US5294799A (en) | 1993-02-01 | 1994-03-15 | Aslund Nils R D | Apparatus for quantitative imaging of multiple fluorophores |
US5545121A (en) | 1993-02-02 | 1996-08-13 | Olympus Optical Co., Ltd. | Cover-type endoscope apparatus |
US5415157A (en) | 1993-02-05 | 1995-05-16 | Welcome; Steven | Damage preventing endoscope head cover |
US5536236A (en) | 1993-02-12 | 1996-07-16 | Olympus Optical Co., Ltd. | Covered endoscope system |
US5419311A (en) | 1993-02-18 | 1995-05-30 | Olympus Optical Co., Ltd. | Endoscope apparatus of a type having cover for covering the endoscope |
US5556367A (en) | 1993-03-05 | 1996-09-17 | Olympus Optical Co., Ltd. | Cover type endoscope apparatus |
US5458133A (en) | 1993-03-15 | 1995-10-17 | Olympus Optical Co., Ltd. | Cover type endoscope apparatus |
US5458132A (en) | 1993-03-15 | 1995-10-17 | Olympus Optical Co., Ltd. | Endoscope cover-sheathed endoscope system |
US5551945A (en) | 1993-03-16 | 1996-09-03 | Olympus Optical Co., Ltd. | Endoscope system including endoscope and protection cover |
US5424543A (en) | 1993-04-19 | 1995-06-13 | Surface Optics Corporation | Imaging spectroradiometer |
US5413108A (en) | 1993-04-21 | 1995-05-09 | The Research Foundation Of City College Of New York | Method and apparatus for mapping a tissue sample for and distinguishing different regions thereof based on luminescence measurements of cancer-indicative native fluorophor |
US5421339A (en) | 1993-05-12 | 1995-06-06 | Board Of Regents, The University Of Texas System | Diagnosis of dysplasia using laser induced fluoroescence |
US5817015A (en) | 1993-06-22 | 1998-10-06 | Adair; Edwin L. | Endoscope with reusable core and disposable sheath with passageways |
US5596992A (en) | 1993-06-30 | 1997-01-28 | Sandia Corporation | Multivariate classification of infrared spectra of cell and tissue samples |
US5995645A (en) | 1993-08-18 | 1999-11-30 | Applied Spectral Imaging Ltd. | Method of cancer cell detection |
CA2131060C (en) | 1993-09-03 | 2005-03-15 | Hiroshi Yamamoto | Non-invasive blood analyzer and method using the same |
US5496259A (en) * | 1993-09-13 | 1996-03-05 | Welch Allyn, Inc. | Sterile protective sheath and drape for video laparoscope and method of use |
US5412563A (en) * | 1993-09-16 | 1995-05-02 | General Electric Company | Gradient image segmentation method |
US5587832A (en) | 1993-10-20 | 1996-12-24 | Biophysica Technologies, Inc. | Spatially light modulated confocal microscope and method |
ZA948393B (en) | 1993-11-01 | 1995-06-26 | Polartechnics Ltd | Method and apparatus for tissue type recognition |
US5746695A (en) | 1993-11-18 | 1998-05-05 | Asahi Kogaku Kogyo Kabushiki Kaisha | Front end structure of endoscope |
JP3257209B2 (en) | 1993-11-30 | 2002-02-18 | ソニー株式会社 | Digital signal recording circuit |
US5983125A (en) | 1993-12-13 | 1999-11-09 | The Research Foundation Of City College Of New York | Method and apparatus for in vivo examination of subcutaneous tissues inside an organ of a body using optical spectroscopy |
US5406939A (en) | 1994-02-14 | 1995-04-18 | Bala; Harry | Endoscope sheath |
US5529235A (en) | 1994-04-28 | 1996-06-25 | Ethicon Endo-Surgery, Inc. | Identification device for surgical instrument |
US5493444A (en) | 1994-04-28 | 1996-02-20 | The United States Of America As Represented By The Secretary Of The Air Force | Photorefractive two-beam coupling nonlinear joint transform correlator |
US5450857A (en) | 1994-05-19 | 1995-09-19 | Board Of Regents, The University Of Texas System | Method for the diagnosis of cervical changes |
JP3379821B2 (en) | 1994-05-31 | 2003-02-24 | オリンパス光学工業株式会社 | Endoscope |
JPH0843204A (en) * | 1994-06-23 | 1996-02-16 | Philips Electron Nv | Multiplex-frequency spectrometer |
EP0689045A1 (en) | 1994-06-23 | 1995-12-27 | Koninklijke Philips Electronics N.V. | Multi-frequency modulation spectrometer |
US5477382A (en) | 1994-08-05 | 1995-12-19 | Northrop Grumman Corporation | Optical correlator system |
JP2802244B2 (en) | 1994-08-29 | 1998-09-24 | オリンパス光学工業株式会社 | Endoscope sheath |
US5599717A (en) * | 1994-09-02 | 1997-02-04 | Martin Marietta Energy Systems, Inc. | Advanced synchronous luminescence system |
US5579773A (en) | 1994-09-30 | 1996-12-03 | Martin Marietta Energy Systems, Inc. | Laser-induced differential normalized fluorescence method for cancer diagnosis |
JP3732865B2 (en) * | 1995-01-18 | 2006-01-11 | ペンタックス株式会社 | Endoscope device |
DE19504174A1 (en) | 1995-02-07 | 1996-08-08 | Siemens Ag | Method for the spectroscopic examination of a biological tissue |
US5894340A (en) * | 1995-02-17 | 1999-04-13 | The Regents Of The University Of California | Method for quantifying optical properties of the human lens |
JP3490817B2 (en) | 1995-03-13 | 2004-01-26 | ペンタックス株式会社 | Endoscope tip |
US5697373A (en) * | 1995-03-14 | 1997-12-16 | Board Of Regents, The University Of Texas System | Optical method and apparatus for the diagnosis of cervical precancers using raman and fluorescence spectroscopies |
US5991653A (en) | 1995-03-14 | 1999-11-23 | Board Of Regents, The University Of Texas System | Near-infrared raman spectroscopy for in vitro and in vivo detection of cervical precancers |
US5735276A (en) * | 1995-03-21 | 1998-04-07 | Lemelson; Jerome | Method and apparatus for scanning and evaluating matter |
US5612540A (en) * | 1995-03-31 | 1997-03-18 | Board Of Regents, The University Of Texas Systems | Optical method for the detection of cervical neoplasias using fluorescence spectroscopy |
US5699795A (en) | 1995-03-31 | 1997-12-23 | Board Of Regents, The University Of Texas System | Optical probe for the detection of cervical neoplasia using fluorescence spectroscopy and apparatus incorporating same |
JP3543027B2 (en) | 1995-04-10 | 2004-07-14 | オリンパス株式会社 | Curved sheath for probe |
JP3476958B2 (en) | 1995-04-12 | 2003-12-10 | アークレイ株式会社 | A method for stabilizing spectra in spectrometry. |
US5690106A (en) | 1995-06-30 | 1997-11-25 | Siemens Corporate Research, Inc. | Flexible image registration for rotational angiography |
US6411835B1 (en) | 1997-01-13 | 2002-06-25 | Medispectra, Inc. | Spectral volume microprobe arrays |
US5713364A (en) | 1995-08-01 | 1998-02-03 | Medispectra, Inc. | Spectral volume microprobe analysis of materials |
US6104945A (en) | 1995-08-01 | 2000-08-15 | Medispectra, Inc. | Spectral volume microprobe arrays |
US5813987A (en) | 1995-08-01 | 1998-09-29 | Medispectra, Inc. | Spectral volume microprobe for analysis of materials |
US5730701A (en) | 1995-09-12 | 1998-03-24 | Olympus Optical Co., Ltd. | Endoscope |
JPH0998938A (en) * | 1995-10-04 | 1997-04-15 | Fuji Photo Optical Co Ltd | Protector of insertion part of endoscope |
US6146897A (en) | 1995-11-13 | 2000-11-14 | Bio-Rad Laboratories | Method for the detection of cellular abnormalities using Fourier transform infrared spectroscopy |
US5795632A (en) | 1996-02-06 | 1998-08-18 | Parker Laboratories | Protective cover set for a medical probe |
US5647368A (en) | 1996-02-28 | 1997-07-15 | Xillix Technologies Corp. | Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract |
JP3796635B2 (en) * | 1996-03-06 | 2006-07-12 | 富士写真フイルム株式会社 | Fluorescence detection device |
US5865726A (en) | 1996-03-27 | 1999-02-02 | Asahi Kogaku Kogyo Kabushiki Kaisha | Front end structure of side-view type endoscope |
US5717209A (en) * | 1996-04-29 | 1998-02-10 | Petrometrix Ltd. | System for remote transmission of spectral information through communication optical fibers for real-time on-line hydrocarbons process analysis by near infra red spectroscopy |
US5807248A (en) | 1996-05-15 | 1998-09-15 | Ohmeda Inc. | Medical monitoring probe with modular device housing |
US5860913A (en) | 1996-05-16 | 1999-01-19 | Olympus Optical Co., Ltd. | Endoscope whose distal cover can be freely detachably attached to main distal part thereof with high positioning precision |
US5931779A (en) * | 1996-06-06 | 1999-08-03 | Wisconsin Alumni Research Foundation | Real-time in-vivo measurement of myoglobin oxygen saturation |
US5773835A (en) | 1996-06-07 | 1998-06-30 | Rare Earth Medical, Inc. | Fiber optic spectroscopy |
WO1997050003A1 (en) * | 1996-06-26 | 1997-12-31 | Morphometrix Technologies Inc. | Confocal ultrasonic imaging system |
US5842995A (en) | 1996-06-28 | 1998-12-01 | Board Of Regents, The Univerisity Of Texas System | Spectroscopic probe for in vivo measurement of raman signals |
US5685822A (en) | 1996-08-08 | 1997-11-11 | Vision-Sciences, Inc. | Endoscope with sheath retaining device |
US5791346A (en) | 1996-08-22 | 1998-08-11 | Western Research Company, Inc. | Colposcope device and method for measuring areas of cervical lesions |
US6119031A (en) | 1996-11-21 | 2000-09-12 | Boston Scientific Corporation | Miniature spectrometer |
US5768333A (en) | 1996-12-02 | 1998-06-16 | Philips Electronics N.A. Corporation | Mass detection in digital radiologic images using a two stage classifier |
CA2192036A1 (en) | 1996-12-04 | 1998-06-04 | Harvey Lui | Fluorescence scope system for dermatologic diagnosis |
US6847490B1 (en) * | 1997-01-13 | 2005-01-25 | Medispectra, Inc. | Optical probe accessory device for use in vivo diagnostic procedures |
JP3654325B2 (en) * | 1997-02-13 | 2005-06-02 | 富士写真フイルム株式会社 | Fluorescence detection device |
US5830146A (en) | 1997-03-17 | 1998-11-03 | Polartechnics Limited | Sheathed probes for tissue type recognition |
US5941834A (en) | 1997-03-17 | 1999-08-24 | Polartechnics Limited | Sheath for a side view probe |
US5855551A (en) | 1997-03-17 | 1999-01-05 | Polartechnics Limited | Integral sheathing apparatus for tissue recognition probes |
US5929985A (en) | 1997-03-18 | 1999-07-27 | Sandia Corporation | Multispectral imaging probe |
US5920399A (en) | 1997-03-18 | 1999-07-06 | Sandia Corporation | Multispectral imaging method and apparatus |
US5989184A (en) | 1997-04-04 | 1999-11-23 | Medtech Research Corporation | Apparatus and method for digital photography useful in cervical cancer detection |
US6008889A (en) | 1997-04-16 | 1999-12-28 | Zeng; Haishan | Spectrometer system for diagnosis of skin disease |
FR2763721B1 (en) * | 1997-05-21 | 1999-08-06 | Inst Nat Rech Inf Automat | ELECTRONIC IMAGE PROCESSING DEVICE FOR DETECTING DIMENSIONAL VARIATIONS |
US6124597A (en) | 1997-07-07 | 2000-09-26 | Cedars-Sinai Medical Center | Method and devices for laser induced fluorescence attenuation spectroscopy |
US6096065A (en) | 1997-09-29 | 2000-08-01 | Boston Scientific Corporation | Sheath for tissue spectroscopy |
US6058322A (en) | 1997-07-25 | 2000-05-02 | Arch Development Corporation | Methods for improving the accuracy in differential diagnosis on radiologic examinations |
US6317617B1 (en) | 1997-07-25 | 2001-11-13 | Arch Development Corporation | Method, computer program product, and system for the automated analysis of lesions in magnetic resonance, mammogram and ultrasound images |
US5921926A (en) | 1997-07-28 | 1999-07-13 | University Of Central Florida | Three dimensional optical imaging colposcopy |
CN1302210A (en) * | 1997-10-20 | 2001-07-04 | 得克萨斯系统大学评议会 | Acetic acid as a signal enhancing contrast agent in fluorescence spectroscopy |
US6091985A (en) * | 1998-01-23 | 2000-07-18 | Research Foundation Of City College Of New York | Detection of cancer and precancerous conditions in tissues and/or cells using native fluorescence excitation spectroscopy |
US6364829B1 (en) * | 1999-01-26 | 2002-04-02 | Newton Laboratories, Inc. | Autofluorescence imaging system for endoscopy |
AU752829B2 (en) * | 1998-01-26 | 2002-10-03 | Brigham And Women's Hospital | Fluorescence imaging endoscope |
WO1999047041A1 (en) * | 1998-03-19 | 1999-09-23 | Board Of Regents, The University Of Texas System | Fiber-optic confocal imaging apparatus and methods of use |
US6505059B1 (en) * | 1998-04-06 | 2003-01-07 | The General Hospital Corporation | Non-invasive tissue glucose level monitoring |
US6285639B1 (en) | 1998-04-29 | 2001-09-04 | Sony Corporation | On-the-fly of jitter during optical disc mastering/recording |
WO1999057529A1 (en) * | 1998-05-04 | 1999-11-11 | The Board Of Regents | Combined fluorescence and reflectance spectroscopy |
US6246479B1 (en) * | 1998-06-08 | 2001-06-12 | Lj Laboratories, L.L.C. | Integrated spectrometer assembly and methods |
US6246471B1 (en) | 1998-06-08 | 2001-06-12 | Lj Laboratories, Llc | Apparatus and method for measuring optical characteristics of an object |
US6243601B1 (en) * | 1998-09-18 | 2001-06-05 | Abund Ottokar Wist | Transillumination imaging instrumentation with scattered light discrimination |
US6377842B1 (en) * | 1998-09-22 | 2002-04-23 | Aurora Optics, Inc. | Method for quantitative measurement of fluorescent and phosphorescent drugs within tissue utilizing a fiber optic probe |
US6169817B1 (en) | 1998-11-04 | 2001-01-02 | University Of Rochester | System and method for 4D reconstruction and visualization |
US6507747B1 (en) * | 1998-12-02 | 2003-01-14 | Board Of Regents, The University Of Texas System | Method and apparatus for concomitant structural and biochemical characterization of tissue |
CA2356195A1 (en) | 1998-12-23 | 2000-06-29 | Medispectra, Inc. | Optical methods and systems for cervical screening |
US6411838B1 (en) | 1998-12-23 | 2002-06-25 | Medispectra, Inc. | Systems and methods for optical examination of samples |
US6556720B1 (en) * | 1999-05-24 | 2003-04-29 | Ge Medical Systems Global Technology Company Llc | Method and apparatus for enhancing and correcting digital images |
US6697666B1 (en) * | 1999-06-22 | 2004-02-24 | Board Of Regents, The University Of Texas System | Apparatus for the characterization of tissue of epithelial lined viscus |
US6208887B1 (en) * | 1999-06-24 | 2001-03-27 | Richard H. Clarke | Catheter-delivered low resolution Raman scattering analyzing system for detecting lesions |
US6717668B2 (en) * | 2000-03-07 | 2004-04-06 | Chemimage Corporation | Simultaneous imaging and spectroscopy apparatus |
JP2001157658A (en) | 1999-12-02 | 2001-06-12 | Fuji Photo Film Co Ltd | Fluorescent image display device |
US20020007122A1 (en) * | 1999-12-15 | 2002-01-17 | Howard Kaufman | Methods of diagnosing disease |
GR1004180B (en) * | 2000-03-28 | 2003-03-11 | ����������� ����� ��������� (����) | Method and system for characterization and mapping of tissue lesions |
US6377841B1 (en) * | 2000-03-31 | 2002-04-23 | Vanderbilt University | Tumor demarcation using optical spectroscopy |
US6312385B1 (en) | 2000-05-01 | 2001-11-06 | Ge Medical Systems Global Technology Company, Llc | Method and apparatus for automatic detection and sizing of cystic objects |
JP4191884B2 (en) * | 2000-08-18 | 2008-12-03 | ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー | Image processing method, image processing apparatus, and image photographing apparatus |
US6718055B1 (en) * | 2000-12-05 | 2004-04-06 | Koninklijke Philips Electronics, N.V. | Temporal and spatial correction for perfusion quantification system |
US6839661B2 (en) * | 2000-12-15 | 2005-01-04 | Medispectra, Inc. | System for normalizing spectra |
USD460821S1 (en) | 2001-02-09 | 2002-07-23 | Medispectra, Inc. | Sheath for cervical optical probe |
USD453964S1 (en) * | 2001-02-09 | 2002-02-26 | Medispectra, Inc. | Sheath for cervical optical probe |
USD453832S1 (en) * | 2001-02-09 | 2002-02-19 | Medispectra, Inc. | Sheath for cervical optical probe |
USD453962S1 (en) * | 2001-02-09 | 2002-02-26 | Medispectra, Inc. | Sheath for cervical optical probe |
USD453963S1 (en) * | 2001-02-09 | 2002-02-26 | Medispectra, Inc. | Sheath for cervical optical probe |
US6933154B2 (en) * | 2002-07-09 | 2005-08-23 | Medispectra, Inc. | Optimal windows for obtaining optical data for characterization of tissue samples |
US7282723B2 (en) * | 2002-07-09 | 2007-10-16 | Medispectra, Inc. | Methods and apparatus for processing spectral data for use in tissue characterization |
US6818903B2 (en) * | 2002-07-09 | 2004-11-16 | Medispectra, Inc. | Method and apparatus for identifying spectral artifacts |
US6768918B2 (en) * | 2002-07-10 | 2004-07-27 | Medispectra, Inc. | Fluorescent fiberoptic probe for tissue health discrimination and method of use thereof |
US7103401B2 (en) * | 2002-07-10 | 2006-09-05 | Medispectra, Inc. | Colonic polyp discrimination by tissue fluorescence and fiberoptic probe |
ATE476908T1 (en) * | 2003-04-18 | 2010-08-15 | Medispectra Inc | SYSTEM AND DIAGNOSTIC METHOD FOR OPTICAL DETECTION OF SUSPICIOUS AREAS IN A TISSUE SAMPLE |
-
1999
- 1999-12-22 US US09/470,071 patent/US6411838B1/en not_active Expired - Lifetime
- 1999-12-22 EP EP99968963A patent/EP1161178A2/en not_active Withdrawn
- 1999-12-22 CA CA002356623A patent/CA2356623C/en not_active Expired - Fee Related
- 1999-12-22 WO PCT/US1999/031001 patent/WO2000037917A2/en not_active Application Discontinuation
- 1999-12-22 JP JP2000589927A patent/JP2002533142A/en active Pending
- 1999-12-22 AU AU27153/00A patent/AU759282B2/en not_active Ceased
-
2000
- 2000-12-15 US US09/738,613 patent/US6385484B2/en not_active Expired - Lifetime
- 2000-12-15 US US09/738,481 patent/US6421553B1/en not_active Expired - Lifetime
-
2002
- 2002-02-08 US US10/071,932 patent/US20020133073A1/en not_active Abandoned
- 2002-06-24 US US10/178,772 patent/US6760613B2/en not_active Expired - Fee Related
-
2004
- 2004-06-17 US US10/870,672 patent/US20050033186A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20010020132A1 (en) | 2001-09-06 |
WO2000037917A3 (en) | 2001-08-23 |
US6411838B1 (en) | 2002-06-25 |
US6760613B2 (en) | 2004-07-06 |
AU2715300A (en) | 2000-07-12 |
JP2002533142A (en) | 2002-10-08 |
US20020183626A1 (en) | 2002-12-05 |
CA2356623C (en) | 2005-10-18 |
WO2000037917A2 (en) | 2000-06-29 |
US20050033186A1 (en) | 2005-02-10 |
US6421553B1 (en) | 2002-07-16 |
US20020133073A1 (en) | 2002-09-19 |
AU759282B2 (en) | 2003-04-10 |
EP1161178A2 (en) | 2001-12-12 |
US6385484B2 (en) | 2002-05-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2356623A1 (en) | Systems and methods for optical examination of samples | |
JP3114298U (en) | Swallowable capsule for in vivo imaging | |
CA2149714A1 (en) | Ophthalmologic apparatus for fundus imaging | |
EP1731087A3 (en) | Compact fluorescent endoscopy video system | |
EP1994881A3 (en) | Endoscopic capsule | |
JPH05507225A (en) | Optical diagnosis and treatment system | |
AU5672296A (en) | Method of observing objects under low levels of illumination and a device for carrying out the said method | |
WO1998028655A3 (en) | Light modulated confocal optical instruments and method | |
ATE408368T1 (en) | TOMOGRAPHIC WAVEFRONT ANALYSIS SYSTEM AND METHOD FOR IMAGING AN OPTICAL SYSTEM | |
DK0830077T3 (en) | Apparatus for detecting electromagnetic reflection from biological tissue | |
EP0659383A3 (en) | Method and apparatus for optical coherence tomographic fundus imaging | |
JPH04150845A (en) | Early cancer diagnosing apparatus | |
EP2267506A3 (en) | Confocal microscopy with multi-spectral encoding | |
NO20053232L (en) | Device for screen display of tissue diagnosis. | |
CA2395287A1 (en) | Methods and apparatus for imaging using a light guide bundle and a spatial light modulator | |
JPH03115958A (en) | Fluorescent observation device for biotissue | |
WO2004091362A3 (en) | Transcleral opthalmic illumination method and system | |
EP1045329A3 (en) | Optical assembly having lens offset from optical axis | |
WO2003027724A3 (en) | Imaging of microarrays using fiber optic exciter | |
ATE364346T1 (en) | EYE EXAMINATION DEVICE | |
JPS56120908A (en) | Distance detecting device for endoscope | |
EP1797818A3 (en) | Method and system for tomographic imaging using fluorescent proteins | |
JP2891923B2 (en) | Lighting structure of microscope | |
JPS63136015A (en) | Endoscope device | |
US20170019575A1 (en) | Optical Methods and Devices For Enhancing Image Contrast In the Presence of Bright Background |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |