CA2362343A1 - Method and composition for treating acne - Google Patents
Method and composition for treating acne Download PDFInfo
- Publication number
- CA2362343A1 CA2362343A1 CA002362343A CA2362343A CA2362343A1 CA 2362343 A1 CA2362343 A1 CA 2362343A1 CA 002362343 A CA002362343 A CA 002362343A CA 2362343 A CA2362343 A CA 2362343A CA 2362343 A1 CA2362343 A1 CA 2362343A1
- Authority
- CA
- Canada
- Prior art keywords
- treating acne
- azelaic acid
- composition
- benzoyl peroxide
- provides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Abstract
The present invention provides a method for treating acne vulgaris by serially applying a topical composition of azelaic acid and a topical composition of benzoyl peroxide. The present invention also provides topical compositions of a peroxide of benzoyl peroxide, and azelaic acid and its derivatives, such as azelaic acid, sodium salt or methylester which are useful for treating acne vulgaris and may be used to simultaneously apply benzoyl peroxide and azelaic acid.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/252,318 US6262117B1 (en) | 1999-02-18 | 1999-02-18 | Method and composition for treating acne |
US09/252,318 | 1999-02-18 | ||
PCT/US2000/003902 WO2000048567A1 (en) | 1999-02-18 | 2000-02-15 | Method and composition for treating acne |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2362343A1 true CA2362343A1 (en) | 2000-08-24 |
CA2362343C CA2362343C (en) | 2008-07-29 |
Family
ID=22955522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002362343A Expired - Fee Related CA2362343C (en) | 1999-02-18 | 2000-02-15 | Method and composition for treating acne |
Country Status (9)
Country | Link |
---|---|
US (1) | US6262117B1 (en) |
EP (1) | EP1152748B1 (en) |
JP (1) | JP2002537240A (en) |
AT (1) | ATE247947T1 (en) |
AU (1) | AU758594B2 (en) |
CA (1) | CA2362343C (en) |
DE (1) | DE60004786T2 (en) |
ES (1) | ES2204552T3 (en) |
WO (1) | WO2000048567A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7897559B2 (en) * | 2000-06-29 | 2011-03-01 | Parks L Dean | Dermatological composition and kit containing avermectin compound for treating dermatological conditions |
US6479060B1 (en) * | 2001-09-04 | 2002-11-12 | Healthpoint, Ltd. | Elegant hydrogenated castor oil ointments |
US6429231B1 (en) * | 2001-09-24 | 2002-08-06 | Bradley Pharmaceuticals, Inc. | Compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use |
US20030064084A1 (en) * | 2001-09-24 | 2003-04-03 | Bradley Pharmaceuticals, Inc. | Novel benzoyl peroxide compositions for the treatment of dermatological disorders and methods for their use |
US7074832B2 (en) | 2001-09-24 | 2006-07-11 | Bradley Pharmaceuticals, Inc. | Compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use |
US20030138466A1 (en) * | 2001-11-28 | 2003-07-24 | Bradley Pharmaceuticals, Inc. | Antioxidant dermatological composition |
US6986896B2 (en) * | 2002-03-20 | 2006-01-17 | Bradley Pharmaceuticals, Inc. | Method of treating fungal conditions of the skin |
US6743417B2 (en) | 2002-04-22 | 2004-06-01 | Bradley Pharmaceuticals, Inc. | Method of treating onychomycosis with urea and an antioxidant |
US20040156870A1 (en) * | 2003-02-11 | 2004-08-12 | Bradley Pharmaceuticals, Inc. | Use of urea as a method for improving the effectiveness of topical anti-inflammatory drugs |
US20050019422A1 (en) * | 2003-07-23 | 2005-01-27 | Allergan, Inc. | Method and composition for treating acne |
US20050074473A1 (en) * | 2003-10-07 | 2005-04-07 | Cabot Corporation | Soft-focus cosmetic composition comprising fumed alumina |
US8158138B1 (en) | 2004-05-20 | 2012-04-17 | Fougera Pharmaceuticals, Inc. | Urea compositions and their methods of manufacture |
ITMI20041567A1 (en) * | 2004-07-30 | 2004-10-30 | Maycos Italiana Di Comini Miro | "N-ACYLATED DERIVATIVES OF BICARBOXYLIC ACIDS WITH AMINO ACIDS AND WITH HYDROLYZED VEGETABLE PROTEINS AND THEIR APPLICATION IN COSMETIC, DERMO-PHARMACEUTICAL AND PHARMACEUTICAL PRODUCTS" |
EP1954294A2 (en) | 2005-11-23 | 2008-08-13 | Ranbaxy Laboratories Limited | Use of macrolide derivatives for treating acne |
US20090203628A1 (en) * | 2008-02-12 | 2009-08-13 | Jan Marini | Composition, Method And Kit For Treating Skin Disorders And Improving Skin Condition |
US20090209604A1 (en) * | 2008-02-14 | 2009-08-20 | Jerry Zhang | Topical combination therapy for treating acne |
WO2010005521A1 (en) * | 2008-06-30 | 2010-01-14 | Bltn, Llc | Azelaic acid ester compositions and methods for diagnosing and treating tissue conditions using azelaic acid ester compositions and proteinaceous biomarkers |
WO2010080543A1 (en) | 2008-12-18 | 2010-07-15 | Guthery B Eugene | Acne vulgaris treatment regimen |
Family Cites Families (40)
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US3849396A (en) | 1973-01-08 | 1974-11-19 | Upjohn Co | Lincomycin and clindamycin 1-o-ethers |
US4132781A (en) | 1974-12-19 | 1979-01-02 | Nelson Research & Development Company | Method for treatment of acne |
US3932653A (en) | 1974-12-19 | 1976-01-13 | Nelson Research & Development Co. | Composition and method for topical administration of griseofulvin |
US3969516A (en) | 1974-12-19 | 1976-07-13 | Nelson Research & Development Company | Composition and method for treatment of acne |
US4018918A (en) | 1975-05-20 | 1977-04-19 | The Upjohn Company | Topical clindamycin preparations |
US3989816A (en) | 1975-06-19 | 1976-11-02 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacycloheptan-2-ones |
US3991203A (en) | 1975-06-19 | 1976-11-09 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclopentan-2-ones |
US4386104A (en) | 1977-04-19 | 1983-05-31 | Nazzaro Porro Marcella | Process for the treatment of acne |
US4318907A (en) * | 1978-04-04 | 1982-03-09 | Westwood Pharmaceuticals, Inc. | Method for treating acne vulgaris and compositions useful for that purpose |
US4505896A (en) | 1979-04-19 | 1985-03-19 | Elorac, Ltd. | Method of treating acne vulgaris and composition |
US4387107A (en) | 1979-07-25 | 1983-06-07 | Dermik Laboratories, Inc. | Stable benzoyl peroxide composition |
US4323558A (en) | 1979-09-10 | 1982-04-06 | Nelson Research & Development Co. | Topical trien containing pharmaceutical compositions and methods of use |
FR2488253A1 (en) | 1980-08-08 | 1982-02-12 | Roques Bernard | NEW PEPTIDES AND THEIR THERAPEUTIC APPLICATION |
US4692329A (en) | 1980-12-08 | 1987-09-08 | William H. Rorer, Inc. | Erythromycin/benzoyl peroxide antiacne compositions |
US4411893A (en) | 1981-08-14 | 1983-10-25 | Minnesota Mining And Manufacturing Company | Topical medicament preparations |
US4607101A (en) | 1981-08-27 | 1986-08-19 | Jaye-Boern Laboratories, Inc. | Method of treating acne vulgaris with a composition containing carbamide peroxide |
JPS59184135A (en) | 1983-04-04 | 1984-10-19 | Teijin Ltd | Medicinal composition containing glycerol pyroglutamate |
LU85111A1 (en) * | 1983-12-01 | 1985-09-12 | Oreal | ANTI-ACNETIC COMPOSITION BASED ON BENZOYL PEROXIDE AND AT LEAST ONE SOLAR FILTER |
US4743588A (en) | 1984-06-13 | 1988-05-10 | Allergan Pharmaceuticals, Inc. | Compositions and methods of enhancing transdermal and transmembrane penetration systemic agents |
JPS6160620A (en) | 1984-09-03 | 1986-03-28 | Teijin Ltd | Pharmaceutical composition containing pyroglutamic acid ester |
US4621075A (en) | 1984-11-28 | 1986-11-04 | The Procter & Gamble Company | Gel-form topical antibiotic compositions |
JPH0643390B2 (en) | 1986-04-08 | 1994-06-08 | 久光製薬株式会社 | Azacycloalkane derivative |
US4916118A (en) | 1986-08-18 | 1990-04-10 | Board Of Regents, The University Of Texas System | Pharmaceutical administration systems containing chemotactic peptides |
FR2604357B1 (en) | 1986-09-30 | 1988-12-02 | Oreal | PHARMACEUTICAL AND ANTI-ACNE COSMETIC COMPOSITION |
FR2604435B1 (en) | 1986-09-30 | 1988-12-02 | Oreal | UNSATURATED AROMATIC PEROXIDES AND THEIR USE IN THERAPEUTICS AND COSMETICS |
US4942031A (en) | 1988-02-23 | 1990-07-17 | Levin Robert H | Compositions containing LYCD and other topically active medicinal ingredients |
US5231087A (en) | 1988-03-16 | 1993-07-27 | Cellegy Pharmaceuticals, Inc. | Treatment of skin diseases and tumors with esters and amides of monocarboxylic acids |
US5260292A (en) * | 1991-03-05 | 1993-11-09 | Marvin S. Towsend | Topical treatment of acne with aminopenicillins |
AU670777B2 (en) * | 1992-04-16 | 1996-08-01 | Ortho Pharmaceutical Corporation | Aqueous gel vehicles for retinoids |
CA2134979A1 (en) | 1992-05-05 | 1993-11-11 | Spencer Guang Lin | Acne treating composition |
BR9306816A (en) | 1992-07-28 | 1998-12-08 | Procter & Gamble | Pharmaceutical composition for topical use containing a cross-linked cationic polymer and an alkoxylated ether |
DE4307976A1 (en) * | 1993-03-15 | 1994-09-22 | Beiersdorf Ag | New use of acne remedies |
WO1994023717A1 (en) | 1993-04-20 | 1994-10-27 | The Procter & Gamble Company | Methods of using hesperetin for sebum control and treatment of acne |
US5538732A (en) * | 1994-04-12 | 1996-07-23 | Creative Products Resource, Inc. | Medicated applicator sheet for topical drug delivery |
US5516950A (en) | 1994-04-15 | 1996-05-14 | Insmed Pharmaceuticals, Inc. | Method for the production of D-chiroinositol |
FR2719044B1 (en) | 1994-04-26 | 1996-05-31 | Cird Galderma | New acetylenated bi-aromatic compounds with adamantyl group, pharmaceutical and cosmetic compositions containing them and uses. |
US5543417A (en) * | 1994-10-21 | 1996-08-06 | Merck & Co., Inc. | Combination method of treating acne using 4-AZA-5α-cholestan-ones and 4-AZA-5α-androstan-ones as selective 5α-reductase inhibitors with anti-bacterial, keratolytic, or anti-inflammatory agents |
JPH10510272A (en) * | 1994-11-28 | 1998-10-06 | ザ、プロクター、エンド、ギャンブル、カンパニー | Topical skin roughening preventing composition containing thickening type polyol carboxylate as skin conditioning agent |
US5618522A (en) | 1995-01-20 | 1997-04-08 | The Procter & Gamble Company | Emulsion compositions |
US5665364A (en) * | 1995-07-24 | 1997-09-09 | The Procter & Gamble Company | Compositions for topical delivery of active ingredients |
-
1999
- 1999-02-18 US US09/252,318 patent/US6262117B1/en not_active Expired - Lifetime
-
2000
- 2000-02-15 AT AT00919302T patent/ATE247947T1/en not_active IP Right Cessation
- 2000-02-15 DE DE60004786T patent/DE60004786T2/en not_active Expired - Fee Related
- 2000-02-15 WO PCT/US2000/003902 patent/WO2000048567A1/en active IP Right Grant
- 2000-02-15 AU AU40012/00A patent/AU758594B2/en not_active Ceased
- 2000-02-15 CA CA002362343A patent/CA2362343C/en not_active Expired - Fee Related
- 2000-02-15 EP EP00919302A patent/EP1152748B1/en not_active Expired - Lifetime
- 2000-02-15 ES ES00919302T patent/ES2204552T3/en not_active Expired - Lifetime
- 2000-02-15 JP JP2000599359A patent/JP2002537240A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU4001200A (en) | 2000-09-04 |
AU758594B2 (en) | 2003-03-27 |
JP2002537240A (en) | 2002-11-05 |
EP1152748B1 (en) | 2003-08-27 |
DE60004786D1 (en) | 2003-10-02 |
EP1152748A1 (en) | 2001-11-14 |
ES2204552T3 (en) | 2004-05-01 |
DE60004786T2 (en) | 2004-08-19 |
US6262117B1 (en) | 2001-07-17 |
CA2362343C (en) | 2008-07-29 |
ATE247947T1 (en) | 2003-09-15 |
WO2000048567A1 (en) | 2000-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20170215 |