CA2370208A1 - Selectively cross-linked polyethylene orthopedic devices - Google Patents
Selectively cross-linked polyethylene orthopedic devices Download PDFInfo
- Publication number
- CA2370208A1 CA2370208A1 CA002370208A CA2370208A CA2370208A1 CA 2370208 A1 CA2370208 A1 CA 2370208A1 CA 002370208 A CA002370208 A CA 002370208A CA 2370208 A CA2370208 A CA 2370208A CA 2370208 A1 CA2370208 A1 CA 2370208A1
- Authority
- CA
- Canada
- Prior art keywords
- medical device
- selectively cross
- linked polyethylene
- cross
- orthopedic devices
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/0266—Local curing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
- B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
- B29C2035/0844—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using X-ray
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
- B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
- B29C2035/085—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using gamma-ray
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
- B29C35/0866—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using particle radiation
- B29C2035/0877—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using particle radiation using electron radiation, e.g. beta-rays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
- B29K2023/04—Polymers of ethylene
- B29K2023/06—PE, i.e. polyethylene
- B29K2023/0608—PE, i.e. polyethylene characterised by its density
- B29K2023/065—HDPE, i.e. high density polyethylene
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
- B29K2023/04—Polymers of ethylene
- B29K2023/06—PE, i.e. polyethylene
- B29K2023/0658—PE, i.e. polyethylene characterised by its molecular weight
- B29K2023/0675—HMWPE, i.e. high molecular weight polyethylene
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
- B29K2023/04—Polymers of ethylene
- B29K2023/06—PE, i.e. polyethylene
- B29K2023/0658—PE, i.e. polyethylene characterised by its molecular weight
- B29K2023/0683—UHMWPE, i.e. ultra high molecular weight polyethylene
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0088—Blends of polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0087—Wear resistance
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/7532—Artificial members, protheses
Abstract
An improved prosthetic medical device having improved wear resistance and toughness is provided in the present application. A method is provided to selectively cross-link the polymeric matrix comprising the medical device by employing an interrupting means such as a mask, wire mesh or chopper wheel placed in between the medical device and irradiation source. In addition, the medical device may be translated while being irradiated to further effect the selective cross-linking. The present invention also provides for an injection molding process wherein a prosthetic medical device is formed in a single step, then selectively cross-linked.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13032299P | 1999-04-21 | 1999-04-21 | |
US60/130,322 | 1999-04-21 | ||
PCT/US2000/010673 WO2000062717A1 (en) | 1999-04-21 | 2000-04-20 | Selectively cross-linked polyethylene orthopedic devices |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2370208A1 true CA2370208A1 (en) | 2000-10-26 |
CA2370208C CA2370208C (en) | 2008-09-09 |
Family
ID=22444146
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002370208A Expired - Lifetime CA2370208C (en) | 1999-04-21 | 2000-04-20 | Selectively cross-linked polyethylene orthopedic devices |
Country Status (7)
Country | Link |
---|---|
US (3) | US6818171B2 (en) |
EP (1) | EP1178764B1 (en) |
JP (1) | JP2002541916A (en) |
AU (1) | AU760210C (en) |
CA (1) | CA2370208C (en) |
DE (1) | DE60028370T2 (en) |
WO (1) | WO2000062717A1 (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8563623B2 (en) * | 1996-02-13 | 2013-10-22 | The General Hospital Corporation | Radiation melt treated ultra high molecular weight polyethylene prosthetic devices |
US8865788B2 (en) * | 1996-02-13 | 2014-10-21 | The General Hospital Corporation | Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices |
US6414086B1 (en) | 2000-02-29 | 2002-07-02 | Howmedica Osteonics Corp. | Compositions, processes and methods of improving the wear resistance of prosthetic medical devices |
US7205339B2 (en) * | 2000-12-12 | 2007-04-17 | Massachusetts General Hospital | Selective controlled manipulation of polymers |
US7819925B2 (en) * | 2002-01-28 | 2010-10-26 | Depuy Products, Inc. | Composite prosthetic bearing having a crosslinked articulating surface and method for making the same |
US7186364B2 (en) * | 2002-01-28 | 2007-03-06 | Depuy Products, Inc. | Composite prosthetic bearing constructed of polyethylene and an ethylene-acrylate copolymer and method for making the same |
CA2429930C (en) | 2002-06-06 | 2008-10-14 | Howmedica Osteonics Corp. | Sequentially cross-linked polyethylene |
JP2006511255A (en) * | 2002-10-11 | 2006-04-06 | カーティフィシャル・アクティーゼルスカブ | Medical devices containing biocompatible polymer products with a layered structure |
US7540845B2 (en) * | 2003-09-05 | 2009-06-02 | Boston Scientific Scimed, Inc | Medical device coil |
US7833175B2 (en) * | 2003-09-05 | 2010-11-16 | Boston Scientific Scimed, Inc. | Medical device coil |
US20050054952A1 (en) * | 2003-09-05 | 2005-03-10 | Scimed Life Systems, Inc. | Elongated medical device for intracorporal use |
FR2885294B1 (en) * | 2005-05-03 | 2008-04-04 | Jerome Levieux | INTERVERTEBRAL DISC PROSTHESIS |
AU2006259555B2 (en) * | 2005-06-14 | 2011-03-03 | Omni Life Science, Inc. | Crosslinked polyethylene article |
US8343230B2 (en) * | 2005-09-22 | 2013-01-01 | Depuy Products, Inc. | Orthopaedic bearing material |
US20070203564A1 (en) * | 2006-02-28 | 2007-08-30 | Boston Scientific Scimed, Inc. | Biodegradable implants having accelerated biodegradation properties in vivo |
DE102006011159A1 (en) * | 2006-03-10 | 2007-09-13 | Benecke-Kaliko Ag | Process for producing a thermoplastic film |
WO2008101134A1 (en) * | 2007-02-14 | 2008-08-21 | Brigham And Women's Hospital, Inc. | Crosslinked polymers and methods of making the same |
CA2697761A1 (en) * | 2007-08-27 | 2009-03-05 | Vladimir Shur | Knee prosthesis |
DE102008029056A1 (en) * | 2008-06-18 | 2009-12-31 | GKN Aerospace Services Limited, East Cowes | Manufacturing method of fiber reinforced composite components with microwaves |
GB0922339D0 (en) * | 2009-12-21 | 2010-02-03 | Mcminn Derek J W | Acetabular cup prothesis and introducer thereof |
US8865051B1 (en) * | 2012-01-24 | 2014-10-21 | Mercury Plastics, Inc. | Method of making a crosslinked overmolded assembly |
DE102012103079A1 (en) * | 2012-04-10 | 2013-10-10 | Krones Ag | Roller conveyor for plastic preforms |
DE102014209882A1 (en) * | 2013-05-23 | 2014-11-27 | Ceram Tec Gmbh | Ceramic component with pore channels |
CN103751849A (en) * | 2013-12-24 | 2014-04-30 | 四川大学 | Ultrahigh molecular weight polyethylene composite material for fusible body processing of artificial joint |
US20150230926A1 (en) * | 2014-02-18 | 2015-08-20 | Biomet Manufacturing, Llc | Method and device for reducing implant contamination from handling |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE544324A (en) | 1955-01-11 | |||
US2904480A (en) | 1955-06-06 | 1959-09-15 | Grace W R & Co | Polyethylene |
US3563869A (en) | 1957-11-05 | 1971-02-16 | Grace W R & Co | Irradiated polyethylene |
US3022543A (en) | 1958-02-07 | 1962-02-27 | Grace W R & Co | Method of producing film having improved shrink energy |
US3057791A (en) | 1959-07-06 | 1962-10-09 | Phillips Petroleum Co | Radiation curing of polymers |
US3090770A (en) | 1960-04-26 | 1963-05-21 | Grace W R & Co | Blended polyethylene compositions of improved clarity and method of making same |
US3162623A (en) | 1961-12-26 | 1964-12-22 | Du Pont | Crosslinking of polymers with nitrogen fluorides |
US3297641A (en) | 1964-01-17 | 1967-01-10 | Grace W R & Co | Process for cross-linking polyethylene |
DE1241994B (en) | 1964-01-31 | 1967-06-08 | Glanzstoff Ag | Process for the saturation of double bonds in polyolefins |
DE1669649B2 (en) | 1966-05-27 | 1971-05-19 | Badische Anilin- & Soda-Fabrik Ag, 6700 Ludwigshafen | PROCESS FOR MANUFACTURING FINE PARTICLE, FOAM-SHAPED OLEFINE POLYMERIZATES WITH HIGH HEAT STABILITY |
US3832827A (en) * | 1967-12-18 | 1974-09-03 | J Lemelson | Container forming and filling apparatus |
US3758273A (en) | 1970-04-03 | 1973-09-11 | Gillette Co | Processes for sterilizing polypropylene objects |
JPS526314B2 (en) | 1971-11-01 | 1977-02-21 | ||
AU523866B2 (en) | 1978-04-18 | 1982-08-19 | Du Pont Canada Inc. | Manufacture of film |
WO1980002671A1 (en) | 1979-06-06 | 1980-12-11 | Nat Res Dev | Polymer processing |
JPS5971830A (en) * | 1982-10-18 | 1984-04-23 | Nippon Sheet Glass Co Ltd | Manufacture of lens of refractive index distribution type |
GB8332952D0 (en) | 1983-12-09 | 1984-01-18 | Ward I M | Polymer irradiation |
US4587163A (en) | 1984-03-06 | 1986-05-06 | Zachariades Anagnostis E | Preparation of ultra high molecular weight polyethylene morphologies of totally fused particles with superior mechanical performance |
EP0157601B1 (en) | 1984-03-30 | 1991-05-08 | National Research Development Corporation | Tubular materials |
EP0161802B1 (en) | 1984-04-13 | 1990-06-27 | National Research Development Corporation | Solid phase deformation process |
US4655769A (en) | 1984-10-24 | 1987-04-07 | Zachariades Anagnostis E | Ultra-high-molecular-weight polyethylene products including vascular prosthesis devices and methods relating thereto and employing pseudo-gel states |
US4820466A (en) | 1985-01-31 | 1989-04-11 | Zachariades Anagnostis E | Process for obtaining ultra-high modulus products |
US4950151A (en) | 1985-01-31 | 1990-08-21 | Zachariades Anagnostic E | Rolling die for producing high modulus products |
DE3545116A1 (en) | 1985-05-17 | 1986-11-20 | Transaktor KB International, Göteborg | BOTTLE FOR WATER EMERGENCY CATERING AND METHOD FOR PRODUCING A BOTTLE WITH WATER EMERGENCY CATERING |
US4701288A (en) * | 1985-06-05 | 1987-10-20 | Bausch & Lomb Incorporated | Method of making articles of dissimilar polymer compositions |
JPS6274364A (en) | 1985-09-27 | 1987-04-06 | 株式会社 ニツシヨ− | Medical applicance |
GB2207436B (en) | 1987-07-24 | 1991-07-24 | Nat Research And Dev Corp The | Solid phase deformation process |
GB8827967D0 (en) | 1988-11-30 | 1989-01-05 | Ward I M | Die-free drawing |
BR8907795A (en) | 1988-12-02 | 1991-08-27 | Du Pont | PROCESS TO PRODUCE MOLDED LINEAR POLYETHYLENE ARTICLES OF ULTRA HIGH MOLECULAR WEIGHT |
US5030402A (en) | 1989-03-17 | 1991-07-09 | Zachariades Anagnostis E | Process for producing a new class of ultra-high-molecular-weight polyethylene orthopaedic prostheses with enhanced mechanical properties |
US5037928A (en) | 1989-10-24 | 1991-08-06 | E. I. Du Pont De Nemours And Company | Process of manufacturing ultrahigh molecular weight linear polyethylene shaped articles |
US5160677A (en) | 1989-12-15 | 1992-11-03 | United States Surgical Corporation | Pressurized powder support for treating processes |
US5153039A (en) | 1990-03-20 | 1992-10-06 | Paxon Polymer Company, L.P. | High density polyethylene article with oxygen barrier properties |
US5348788A (en) | 1991-01-30 | 1994-09-20 | Interpore Orthopaedics, Inc. | Mesh sheet with microscopic projections and holes |
US5508319A (en) | 1991-06-21 | 1996-04-16 | Montell North America Inc. | High melt strength, ethylene polymer, process for making it, and use thereof |
US5222949A (en) | 1991-07-23 | 1993-06-29 | Intermed, Inc. | Flexible, noncollapsible catheter tube with hard and soft regions |
US5414049A (en) | 1993-06-01 | 1995-05-09 | Howmedica Inc. | Non-oxidizing polymeric medical implant |
US5849437A (en) | 1994-03-25 | 1998-12-15 | Fujitsu Limited | Electron beam exposure mask and method of manufacturing the same and electron beam exposure method |
EP0729981B1 (en) * | 1994-09-21 | 2002-03-20 | Bmg Incorporated | Ultrahigh-molecular-weight polyethylene molding for artificial joint and process for producing the molding |
US5962023A (en) | 1995-03-06 | 1999-10-05 | Ethicon, Inc. | Hydrogels containing absorbable polyoxaamides |
US5879400A (en) * | 1996-02-13 | 1999-03-09 | Massachusetts Institute Of Technology | Melt-irradiated ultra high molecular weight polyethylene prosthetic devices |
JP3565652B2 (en) * | 1996-04-25 | 2004-09-15 | 富士通株式会社 | Transmission mask for charged particle beam exposure apparatus and exposure apparatus using the same |
US6017975A (en) | 1996-10-02 | 2000-01-25 | Saum; Kenneth Ashley | Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance |
AU4986497A (en) * | 1996-10-15 | 1998-05-11 | Orthopaedic Hospital, The | Wear resistant surface-gradient cross-linked polyethylene |
US6432349B1 (en) * | 1999-06-29 | 2002-08-13 | Zimmer, Inc. | Process of making an articulating bearing surface |
US6143232A (en) * | 1999-07-29 | 2000-11-07 | Bristol-Meyers Squibb Company | Method of manufacturing an articulating bearing surface for an orthopaedic implant |
US6365089B1 (en) * | 1999-09-24 | 2002-04-02 | Zimmer, Inc. | Method for crosslinking UHMWPE in an orthopaedic implant |
-
2000
- 2000-04-20 EP EP00928245A patent/EP1178764B1/en not_active Expired - Lifetime
- 2000-04-20 JP JP2000611855A patent/JP2002541916A/en active Pending
- 2000-04-20 DE DE60028370T patent/DE60028370T2/en not_active Expired - Lifetime
- 2000-04-20 WO PCT/US2000/010673 patent/WO2000062717A1/en active IP Right Grant
- 2000-04-20 CA CA002370208A patent/CA2370208C/en not_active Expired - Lifetime
- 2000-04-20 AU AU46506/00A patent/AU760210C/en not_active Expired
-
2002
- 2002-03-11 US US10/095,240 patent/US6818171B2/en not_active Expired - Lifetime
- 2002-03-11 US US10/094,789 patent/US6849224B2/en not_active Expired - Lifetime
-
2004
- 2004-08-30 US US10/931,235 patent/US20050113935A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1178764A1 (en) | 2002-02-13 |
US6818171B2 (en) | 2004-11-16 |
EP1178764A4 (en) | 2003-04-02 |
AU760210C (en) | 2004-10-07 |
EP1178764B1 (en) | 2006-05-31 |
WO2000062717A1 (en) | 2000-10-26 |
DE60028370D1 (en) | 2006-07-06 |
CA2370208C (en) | 2008-09-09 |
US20050113935A1 (en) | 2005-05-26 |
JP2002541916A (en) | 2002-12-10 |
AU4650600A (en) | 2000-11-02 |
DE60028370T2 (en) | 2007-05-03 |
US20020093124A1 (en) | 2002-07-18 |
US20020100879A1 (en) | 2002-08-01 |
US6849224B2 (en) | 2005-02-01 |
AU760210B2 (en) | 2003-05-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2370208A1 (en) | Selectively cross-linked polyethylene orthopedic devices | |
CA2166450A1 (en) | Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints | |
EP0713893A4 (en) | Hydrogenated norbornene-base ring-opening polymer, process for producing the same, and use thereof | |
HK1056183A1 (en) | Crosslinked polymer, process for producing the same, absorbent structure, and absorbable article | |
BR0016681B1 (en) | fabric softener composition, and, fabric treatment method. | |
WO2002041837A3 (en) | Treatment of mucositis | |
WO2002048259A3 (en) | Selective, controlled manipulation of polymers | |
DE69528739D1 (en) | Vivo degradable medical device, composition and method for its manufacture and decomposition | |
DE60300403D1 (en) | Sequentially cross-linked polyethylene for medical implants | |
ES2132041T1 (en) | IMPROVED PROCESSABILITY AND RETENTION RESISTANCE WHEN SILANIZED PIGMENTS ARE INCORPORATED IN POLYMERS. | |
DE59803468D1 (en) | METHOD FOR PRODUCING SOLVENT-FREE, NON-CRYSTALLINE BIOLOGICALLY ACTIVE SUBSTANCES | |
DE69334082D1 (en) | Disinfecting iodine resin, process for its preparation and use in textile combinations | |
ZA200001883B (en) | Methods and apparatus for producing and treating novel elastomer composites. | |
DE68913894T2 (en) | Process for making a polymer gel, polymer gel and actuator using the same. | |
AU2003288732A1 (en) | Polymeric compositions rapidly heatable under electromagnetic irradiation, their uses and processing methods | |
AU1645995A (en) | Leather treatment process for leather coloring, leather coloring process performed on leather thereby treated, and leather article produced by the leather coloring process | |
DE69720571D1 (en) | Oxygen absorbing resin composition and packaging material, multilayer packaging material, packaging and packaging method using the same | |
BR9714089A (en) | Stable and breathable films with improved stretch and manufacturing method | |
AU3467300A (en) | Method for treating glaucoma, device for realising the same and variants | |
WO2001054735A3 (en) | Gel-infused sponges for tissue repair and augmentation | |
ATE390113T1 (en) | USE OF MOLDING MATERIALS FOR PRODUCING TREATMENT DEVICES | |
MX9803459A (en) | System or apparatus for treating the ureter and/or pyelo-ureter junction. | |
DE69717155T2 (en) | TASTE-COMPATIBLE SILICONE GEL, METHOD FOR THE PRODUCTION THEREOF AND THE TOOTHPASTE COMPOSITION THEREOF | |
BR9204924A (en) | AGRICULTURAL ASSOCIATION, AGRICULTURAL COMPOSITION AND PLANT TREATMENT PROCESS | |
DE59909502D1 (en) | Antibacterial agent for filling root canals and manufacturing process |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20200420 |