CA2373278A1 - Medicament delivery device with measuring chamber and dispensing cup - Google Patents

Medicament delivery device with measuring chamber and dispensing cup Download PDF

Info

Publication number
CA2373278A1
CA2373278A1 CA002373278A CA2373278A CA2373278A1 CA 2373278 A1 CA2373278 A1 CA 2373278A1 CA 002373278 A CA002373278 A CA 002373278A CA 2373278 A CA2373278 A CA 2373278A CA 2373278 A1 CA2373278 A1 CA 2373278A1
Authority
CA
Canada
Prior art keywords
medicament
delivery device
inhaler
reservoir
medicament delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002373278A
Other languages
French (fr)
Other versions
CA2373278C (en
Inventor
Philip Braithwaite
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innovata Biomed Ltd
Original Assignee
Innovata Biomed Limited
Philip Braithwaite
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26315636&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2373278(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9913047.8A external-priority patent/GB9913047D0/en
Priority claimed from GBGB9916283.6A external-priority patent/GB9916283D0/en
Application filed by Innovata Biomed Limited, Philip Braithwaite filed Critical Innovata Biomed Limited
Priority to CA2725731A priority Critical patent/CA2725731A1/en
Publication of CA2373278A1 publication Critical patent/CA2373278A1/en
Application granted granted Critical
Publication of CA2373278C publication Critical patent/CA2373278C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Refuse Collection And Transfer (AREA)
  • Cyclones (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Feeding And Watering For Cattle Raising And Animal Husbandry (AREA)
  • Threshing Machine Elements (AREA)

Abstract

There is described a medicament delivery device (1) which comprises a medicament reservoir (2), a medicament delivery passage (3) and a metering member (4) adapted to transfer a measured dose of medicament from the medicament reservoir to the delivery passage characterised in that the devic e is provided with a moisture proof barrier (9). The medicament delivery devic e is especially suited for use as an inhaler. There is therefore also decribed an inhaler which provides improved airflow for the dispersion of medicament, and a method of treating patients suffering from a respiratory disorder.</SD OAB>

Claims (25)

1. A medicament delivery device (1) which comprises a medicament reservoir (2), a medicament delivery passage (3) and a metering member (4) adapted to transfer a measured dose of medicament from the medicament reservoir (2) to the delivery passage (3), the device (1) being provided with a moisture proof barrier (9) characterised in that the moisture proof barrier (9) comprises a resilient sealing member in a fixed position.
2. A medicament delivery device (1) according to Claim 1 characterised in that the moisture proof barrier is a moisture proof (9) sealing means.
3. A medicament delivery device (1) according to claim 1 characterised in that the moisture proof barrier (9) is positioned to prevent ingress of moisture into the medicament reservoir (2).
4. A medicament delivery device (1) according to Claim 1 wherein the sealing means is adapted to move from an inoperable position in which the medicament reservoir (2) is sealed, to an operable position in which the seal is broken so that measurement and/or delivery of a dose of medicament may take place.
5. A medicament delivery device (1) according to Claim 1 wherein the sealing means comprises a resilient sealing member positioned at the end of the medicament reservoir (2) adjacent the metering member (4).
6. A medicament delivery device according to Claim 5 wherein the metering member (4) is biased towards the sealing member (9).
7. A medicament delivery device (1) according to claim 1 characterised in that the delivery device is an inhaler.
8. A medicament delivery device (1) according to claim 7 characterised in that the inhaler is a dry powder inhaler.
9. A medicament delivery device (1) according to Claim 4 characterised in that the metering member (4) is rotatable from an operable to an inoperable position.
10. A medicament delivery device (1) according to Claim 1 characterised in that the metering member (4) comprises a combination of a dispensing member (10) and an outer sleeve.
11. A medicament delivery device (1) according to Claim 10 characterised in that the outer sleeve is a moisture resistant sleeve (9).
12. A medicament delivery device (1) according to Claim 11 characterised in that the moisture resistant sleeve (9) is adapted to act as a medicament measuring device.
13. A medicament delivery device (1) according to claim 12 wherein the moisture resistant sleeve is a frusto hemispherical cone (22).
14. A medicament delivery device (1) according to Claim 1 characterised in that the device may be moved to a first position in which the medicament is transferred to a measuring chamber, the device is then moved to a second position. in which medicament is transferred to a dispensing chamber and to a third position where medicament is delivered into the delivery passage (3).
15. A medicament delivery device (1) which is an inhaler and comprises a medicament reservoir (2), an inhalation passage (3) and a metering member (4) provided with at least one dispensing cup (13) and adapted to transfer a measured dose of medicament from the medicament reservoir (2) to the inhalation passage (3) characterised in that the dispensing cup (13) is provided with an air duct (14).
16. An inhaler according to Claim 15 characterised in that the device is provided with a moisture proof barrier.
17. An inhaler comprising a medicament reservoir (2), an inhalation passage (3) for the delivery of the medicament and a metering member (4) adapted to transfer a measured dose of medicament from the medicament reservoir (2) to the inhalation passage (3) characterised in that the metering member (4) comprises a measuring member adapted to measure a pre-defined dosage of medicament and moveable from a measuring to a non-measuring position;
and a dispensing member adapted to receive the measured dosage of medicament from the measuring member and to deliver the medicament to the inhalation passage, the dispensing member being moveable from a medicament receiving position to a medicament delivering position.
18. An inhaler according to Claim 17 wherein the second member is provided with one or more medicament receiving cups, said cups being provided with an air duct so as to provide a flow of air through the passage and the cup into the inhalation passage upon operation of the device.
19. An inhaler comprising a medicament reservoir (2), an inhalation passage (3) for the delivery of the medicament and a metering member (4) adapted to transfer a measured dose of medicament from the medicament reservoir (2) characterised in that the metering member (4) is provided with a duct (14) to allow air to be sucked through the metering member upon inhalation by a patient.
20. An inhaler according to claim 19 characterised in that the metering member (4) comprises an outer sleeve and a dispensing member (10).
21. A medicament delivery device (1) according to claim 20 characterised in that the duct is part of a measuring cup in the dispensing member.
22. A method of administering a medicament by inhalation which comprises the use by a patient of an inhaler according to claim 1.
23. A method of administering a dry powder inhalation medicament using an inhaler according to Claim 7.
24. A method of treatment of a patient with a respiratory disorder which comprises the administration of a combination of medicaments using an inhaler according to Claim 7.
25. A medicament delivery device (1) substantially as described with reference to the accompanying drawings.
CA2373278A 1999-06-05 2000-06-05 Medicament delivery device with measuring chamber and dispensing cup Expired - Fee Related CA2373278C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2725731A CA2725731A1 (en) 1999-06-05 2000-06-05 Delivery system

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9913047.8A GB9913047D0 (en) 1999-06-05 1999-06-05 Inhaler
GB9913047.8 1999-06-05
GBGB9916283.6A GB9916283D0 (en) 1999-07-13 1999-07-13 Inhaler
GB9916283.6 1999-07-13
PCT/GB2000/002017 WO2000074754A2 (en) 1999-06-05 2000-06-05 Delivery system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2725731A Division CA2725731A1 (en) 1999-06-05 2000-06-05 Delivery system

Publications (2)

Publication Number Publication Date
CA2373278A1 true CA2373278A1 (en) 2000-12-14
CA2373278C CA2373278C (en) 2011-04-05

Family

ID=26315636

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2725731A Abandoned CA2725731A1 (en) 1999-06-05 2000-06-05 Delivery system
CA2373278A Expired - Fee Related CA2373278C (en) 1999-06-05 2000-06-05 Medicament delivery device with measuring chamber and dispensing cup

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA2725731A Abandoned CA2725731A1 (en) 1999-06-05 2000-06-05 Delivery system

Country Status (16)

Country Link
US (3) US7207330B1 (en)
EP (1) EP1183061B2 (en)
JP (1) JP4540906B2 (en)
AT (1) ATE294608T1 (en)
AU (1) AU777278B2 (en)
BR (1) BR0011343A (en)
CA (2) CA2725731A1 (en)
DE (1) DE60019920T2 (en)
ES (1) ES2241611T3 (en)
IL (1) IL146886A0 (en)
MX (1) MXPA01012533A (en)
NO (1) NO20015910L (en)
NZ (2) NZ515557A (en)
PL (1) PL352615A1 (en)
PT (1) PT1183061E (en)
WO (1) WO2000074754A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7258118B2 (en) 2002-01-24 2007-08-21 Sofotec Gmbh & Co, Kg Pharmaceutical powder cartridge, and inhaler equipped with same
DE10202940A1 (en) 2002-01-24 2003-07-31 Sofotec Gmbh & Co Kg Cartridge for a powder inhaler
DE10300032B3 (en) * 2003-01-03 2004-05-27 E. Braun Gmbh Inhaler for powdered medicament has pivoted inhalation tube which shuts off powder supply when in out-of-use position, and doses powder into airflow when in use
SE0303269L (en) * 2003-12-03 2005-06-04 Microdrug Ag Medical product
SE0303570L (en) * 2003-12-03 2005-06-04 Microdrug Ag Moisture-sensitive medical product
EP1691783B1 (en) * 2003-12-03 2009-11-25 Boehringer Ingelheim International GmbH Pre-metered dry powder inhaler for moisture-sensitive medicaments
SE0303270L (en) * 2003-12-03 2005-06-04 Microdrug Ag Method of administration of tiotropium
EP1691782A1 (en) * 2003-12-03 2006-08-23 Microdrug AG Medical product containing tiotropium
GB2410192B (en) * 2004-01-23 2005-12-07 Eg Technology Ltd An inhaler
ITMO20040060A1 (en) * 2004-03-18 2004-06-18 Roberto Oliva INHALER FOR POWDER PREPARATIONS
KR101214823B1 (en) 2004-07-16 2012-12-24 알미랄, 에스.에이. Inhaler for the administration of powdered pharmaceuticals, and a powder cartridge system for use with this inhaler
SE0402345L (en) * 2004-09-24 2006-03-25 Mederio Ag Measured drug dose
BRPI0720846A2 (en) 2006-12-22 2014-03-04 Almirall Lab INHALATION DEVICE FOR POWDERED DRUGS
EP2230934B8 (en) 2007-12-14 2012-10-24 AeroDesigns, Inc Delivering aerosolizable food products
US8985102B2 (en) 2009-05-18 2015-03-24 Adamis Pharmaceuticals Corporation Dry powder inhalers
GB0912373D0 (en) 2009-07-16 2009-08-26 Innovata Biomed Ltd Improvements in or relating to dry powder inhalers
CA2780138A1 (en) 2009-11-24 2011-06-03 Gilead Sciences, Inc. Inhaled fosfomycin/tobramycin for the treatment of chronic obstructive pulmonary disease
WO2011081937A1 (en) 2009-12-15 2011-07-07 Gilead Sciences, Inc. Corticosteroid-beta-agonist-muscarinic antagonist compounds for use in therapy
UY33372A (en) 2010-05-10 2011-12-30 Gilead Sciences Inc ? QUINOLINA BI? FUNCTIONAL ANALOGS, ITS USE IN THE MANUFACTURE OF MEDICINES, COMPOSITIONS THAT UNDERSTAND AND PREPARATION PROCESSES ?.
WO2011143106A1 (en) 2010-05-10 2011-11-17 Gilead Sciences, Inc. Bi - functional pyrazolopyridine compounds
WO2012154483A1 (en) 2011-05-06 2012-11-15 Gilead Sciences, Inc. Dry powder fosfomycin/tobramycin formulation for inhalation
AR086745A1 (en) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-DIAMINO-6-CHLORINE-N- (N- (4- (4- (2- (HEXIL (2,3,4,5,6-PENTAHYDROXIHEXIL)) AMINO) ETOXI) PHENYL) BUTIL) CARBAMIMIDOIL) PIRAZINA -2-CARBOXAMIDE
KR102109223B1 (en) 2012-05-29 2020-05-11 패리온 사이언스 인코퍼레이티드 Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases
RU2018138195A (en) 2012-12-17 2018-12-18 Пэрион Сайенсиз, Инк. COMPOUNDS 3,5-DIAMINO-6-CHLORO-N- (N- (4-Phenylbutyl) Carbamimidoyl) Pyrazine-2-Carboxamide
PE20151054A1 (en) 2012-12-17 2015-08-07 Parion Sciences Inc CHLORINE-PIRAZINE CARBOXAMIDE DERIVATIVES WITH BLOCKING ACTIVITY ON THE EPITHELIAL SODIUM CHANNELS
CA2896686A1 (en) 2012-12-17 2014-06-26 Parion Sciences, Inc. 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
SG11201811262QA (en) * 2016-07-21 2019-01-30 Philip Morris Products Sa Dry powder inhaler
WO2023117929A1 (en) * 2021-12-21 2023-06-29 Chiesi Farmaceutici S.P.A. Powder inhaler

Family Cites Families (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1858735A (en) 1930-07-03 1932-05-17 Elwin M Goodsell Dispenser for tobacco or granular material
US2587215A (en) 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US3008609A (en) 1959-07-13 1961-11-14 United States Borax Chem Dispenser for powdered materials
LU53824A1 (en) 1967-06-06 1969-03-24
JPS4837815B1 (en) 1970-09-25 1973-11-14 Yamanouchi Pharma Co Ltd
US3876269A (en) 1973-04-23 1975-04-08 James N Fisher Preprogrammed medication dispenser
US3854626A (en) 1973-04-30 1974-12-17 J Krechmar Pill container-dispenser
US3874381A (en) 1974-05-28 1975-04-01 Smithkline Corp Dual nozzle intranasal delivery device
US4047635A (en) 1975-08-28 1977-09-13 Bennett Jr Arthur A Article dispensing apparatus for selectively dispensing articles
SE408265B (en) 1975-12-12 1979-06-05 Draco Ab DEVICE FOR CARBON DIOXIDE POWERED ENDOSAEROSOL, INTENDED FOR INHALATION
DE2623626C3 (en) * 1976-05-26 1980-09-11 Chemische Fabrik Stockhausen & Cie, 4150 Krefeld Packaging and dispenser for free-flowing materials at the same time
DE2716323C2 (en) 1977-04-07 1986-03-13 Schering AG, 1000 Berlin und 4709 Bergkamen Device for inhalation of medicaments
US4174034A (en) * 1978-04-17 1979-11-13 Hoo William K C Safety container having a slideable closure
US4274403A (en) 1979-08-29 1981-06-23 Struve Roger L Inhaler
ES8206980A1 (en) 1980-10-30 1982-09-01 Riker Laboratories Inc Powder inhalation device.
CY1492A (en) 1981-07-08 1990-02-16 Draco Ab Powder inhalator
FI79651C (en) 1982-10-08 1990-02-12 Glaxo Group Ltd Dosing device for medicine
US4570630A (en) 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
US4604847A (en) 1983-09-14 1986-08-12 Moulding Jr Thomas S Medicine package, method of opening the package, and machine for performing the method
US4534343A (en) 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
US4624442A (en) 1985-01-23 1986-11-25 Duffy John W Control regulator having a rolling diaphragm
SE448277B (en) 1985-04-12 1987-02-09 Draco Ab INDICATOR DEVICE WITH A DOSAGE DEVICE FOR MEDICINAL PRODUCTS
US5192528A (en) 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
JPS63500175A (en) 1985-05-22 1988-01-21 リポソ−ム　テクノロジ−，インコ−ポレイテツド Liposome inhalation method and inhalation system
US4635829A (en) 1985-05-30 1987-01-13 Brittingham Jr Louis W Measured volume dispenser
US4811731A (en) 1985-07-30 1989-03-14 Glaxo Group Limited Devices for administering medicaments to patients
SE453566B (en) 1986-03-07 1988-02-15 Draco Ab POWDER INHALATOR DEVICE
SE8601351D0 (en) 1986-03-24 1986-03-24 Nilsson Sven Erik MANAGED ADMINISTRATION OF PHYSIOLOGICALLY ACTIVE SUBJECTS
US5053237A (en) 1987-03-23 1991-10-01 Hendricks Deloy G Method for tenderizing and upgrading the sensory qualities of red meat
US4882210A (en) 1988-09-26 1989-11-21 The West Company Glass container
US4950365A (en) 1988-12-22 1990-08-21 Vac-Tec Systems, Inc. Corrosion free hard coated metal substrates
US5208226A (en) 1989-09-08 1993-05-04 Glaxo Group Limited Medicaments
US5007419A (en) 1989-09-25 1991-04-16 Allan Weinstein Inhaler device
US5067491A (en) 1989-12-08 1991-11-26 Becton, Dickinson And Company Barrier coating on blood contacting devices
US5002048A (en) 1989-12-12 1991-03-26 Makiej Jr Walter J Inhalation device utilizing two or more aerosol containers
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
US5113855A (en) * 1990-02-14 1992-05-19 Newhouse Michael T Powder inhaler
DE4004904A1 (en) * 1990-02-16 1990-09-13 Gerhard Brendel DRUM APPLICATOR
US5064083A (en) 1990-03-08 1991-11-12 The West Company, Incorporated Closure device
IT1240750B (en) 1990-04-12 1993-12-17 Chiesi Farma Spa DEVICE FOR THE ADMINISTRATION OF MEDICAMENTOUS POWDER SUBSTANCES
FR2662672B1 (en) 1990-05-31 1992-08-21 Aerosols & Bouchage MIXTURE DISPENSER.
GB9015522D0 (en) † 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
IT1243344B (en) 1990-07-16 1994-06-10 Promo Pack Sa MULTI-DOSE INHALER FOR POWDER MEDICATIONS
DE4027390C2 (en) 1990-08-30 1994-11-03 Boehringer Ingelheim Kg Propellant-free inhalation device
DE4027391A1 (en) 1990-08-30 1992-03-12 Boehringer Ingelheim Kg GAS-FREE INHALATION DEVICE
FR2667509B1 (en) 1990-10-04 1995-08-25 Valois POWDER INHALER, DEVICE FOR PACKAGING POWDER MICRODOSES IN THE FORM OF BANDS SUITABLE FOR USE IN A POWDER INHALER, AND METHOD FOR MANUFACTURING SUCH BANDS.
US5042472A (en) 1990-10-15 1991-08-27 Merck & Co., Inc. Powder inhaler device
GB9026025D0 (en) * 1990-11-29 1991-01-16 Boehringer Ingelheim Kg Inhalation device
GB9027234D0 (en) * 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
US5152422A (en) 1990-12-17 1992-10-06 Springer Reinhold A Medication dispenser
AU6130694A (en) 1991-03-05 1994-08-15 Miris Medical Corporation An automatic aerosol medication delivery system and methods
US5154326A (en) 1991-03-07 1992-10-13 Gain Lab Corporation Vibrator and screw combined conveying device used in weighing of powder
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
KR960002186B1 (en) † 1991-04-15 1996-02-13 레이라스 오와이 Device intended for measuring a dose of powdered medicament for
FR2676929B1 (en) † 1991-05-30 1994-02-11 Aerosols Bouchage Ste Fse POWDER INHALER.
IT1248059B (en) † 1991-06-14 1995-01-05 Miat Spa MULTI-DOSE INSUFFLATOR FOR POWDER DRUGS
CZ282291B6 (en) * 1991-06-26 1997-06-11 Schering Corporation Inhalator for powder substances
ATE359842T1 (en) 1991-07-02 2007-05-15 Nektar Therapeutics DISPENSING DEVICE FOR MIST-FORMED MEDICATIONS
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US6119688A (en) * 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
JPH06509958A (en) † 1991-08-26 1994-11-10 ミネソタ　マイニング　アンド　マニュファクチャリング　カンパニー powder dispenser
DE4211475A1 (en) 1991-12-14 1993-06-17 Asta Medica Ag POWDER INHALATOR
GB9203761D0 (en) † 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
DE4208880A1 (en) 1992-03-19 1993-09-23 Boehringer Ingelheim Kg SEPARATOR FOR POWDER INHALATORS
US5253782A (en) 1992-05-20 1993-10-19 Paul A. Wiebel Article dispensing apparatus
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
TW223015B (en) 1992-07-01 1994-05-01 Duphar Int Res
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
GB2270293A (en) 1992-09-05 1994-03-09 Medix Ltd Drug dispensing system
DE4239402A1 (en) 1992-11-24 1994-05-26 Bayer Ag Multiple dosage powder inhaler - has acceleration channel and dwell chamber for uniformly high drug dispersion
CZ287848B6 (en) 1992-12-18 2001-02-14 Schering Corp Inhalator of powder substances
US5896855A (en) 1992-12-24 1999-04-27 Rhone-Poulenc Rorer Limited Multi dose inhaler apparatus
US5411175A (en) 1993-03-08 1995-05-02 New England Pharmaceuticals, Inc. Cartridges, devices and methods for dispensing liquids
GB9306703D0 (en) * 1993-03-31 1993-05-26 Fisons Plc Inhalation device
GB9312984D0 (en) 1993-06-23 1993-08-04 Bespak Plc Atomising dispenser
US5437267A (en) 1993-08-03 1995-08-01 Weinstein; Allan Device for delivering aerosol to the nasal membranes and method of use
US5524613A (en) 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
DE4340768A1 (en) * 1993-11-30 1995-06-01 Bayer Ag Inhalation device
US5450160A (en) 1993-12-22 1995-09-12 Eastman Kodak Company Film cartridge magazine
US5415162A (en) 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
US5664557A (en) 1994-03-10 1997-09-09 Respiratory Delivery Systems, Inc. Releasably engageable coupling for an inhaler
FI942196A (en) † 1994-05-11 1995-11-12 Orion Yhtymae Oy powder inhaler
FI95441C (en) † 1994-05-31 1996-02-12 Leiras Oy Inhaler drug chamber
US5562231A (en) 1994-07-29 1996-10-08 Ortho Pharmaceutical Corporation Variable day start tablet dispenser
US5775536A (en) 1994-07-29 1998-07-07 Ortho Pharmaceutical Corp. Variable day start tablet dispenser
MX9701957A (en) * 1994-09-16 1998-02-28 Glaxo Wellcome Lab Sa Inhalation device.
EP0705928B1 (en) 1994-10-07 1999-08-11 Sulzer RàœTi Ag Trolley for the exchange of the harness of a loom
US5485939A (en) 1994-11-09 1996-01-23 Tucker; Gary D. Lollipop dispenser apparatus
GB9426252D0 (en) 1994-12-24 1995-02-22 Glaxo Group Ltd Pharmaceutical composition
US5622166A (en) 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5921237A (en) 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
AU128811S (en) 1995-06-06 1996-12-03 Orion Yhtymae Oy A protective cover for example a moisture protective cover for a powder inhaler
SE504458C2 (en) 1995-06-21 1997-02-17 Lars Gunnar Nilsson Inhalator for electrical dosing of substances
DE19523516C1 (en) 1995-06-30 1996-10-31 Asta Medica Ag Inhaler for administering medication from blister packs
JP3317823B2 (en) * 1995-08-11 2002-08-26 株式会社ユニシアジェックス Dosing device
DE19530240A1 (en) * 1995-08-17 1997-02-20 Gerhard Brendel Multi dose powder inhalator
US5664697B1 (en) 1995-10-31 1998-09-15 Ortho Pharma Corp Automatically advancing pill regimen device
CZ212598A3 (en) 1996-01-03 1998-11-11 Glaxo Group Limited Inhalation apparatus
JP3830972B2 (en) 1996-02-21 2006-10-11 シェーリング コーポレイション Powder medicine inhaler
US5875776A (en) * 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US6254854B1 (en) 1996-05-24 2001-07-03 The Penn Research Foundation Porous particles for deep lung delivery
FR2753791B1 (en) * 1996-09-20 1998-11-20 POWDER DISPENSER WITH TILTING DOSING CHAMBER
GB9626233D0 (en) * 1996-12-18 1997-02-05 Chawla Brinda P S Medicament packaging and deliveery device
GB9626263D0 (en) * 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
GB9700226D0 (en) * 1997-01-08 1997-02-26 Glaxo Group Ltd Inhalation device
SE9700424D0 (en) * 1997-02-07 1997-02-07 Astra Ab Powder inhales
US5981549A (en) 1997-02-14 1999-11-09 Synapse Pharmaceutical International Method for controlling or alleviating the symptoms of respiratory disease and allergies
US6006747A (en) 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5904139A (en) 1997-03-28 1999-05-18 Hauser; Stephen G. Breath coordinated inhaler
US5941241A (en) 1997-05-12 1999-08-24 Weinstein; Robert E. Method and device for organizing and coordinating the combined use of topical aerosols for the treatment of respiratory disorders
US5944660A (en) 1997-07-08 1999-08-31 Optical Sensors Incorporated Disposable cartridge assembly with optional integrated temperature control system, and systems containing same
CA2212430A1 (en) * 1997-08-07 1999-02-07 George Volgyesi Inhalation device
GB9722285D0 (en) * 1997-10-23 1997-12-17 Rhone Poulenc Rorer Ltd Inhalation device
US6116238A (en) 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
EP1044029B1 (en) * 1998-01-03 2003-10-08 Innovata Biomed Limited Filling method
DE19803524A1 (en) 1998-01-30 1999-08-05 Grohe Armaturen Friedrich Actuator for a water valve
US6125844A (en) 1998-04-30 2000-10-03 Westwood Biomedical Portable oxygen based drug delivery system
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
US6325241B1 (en) 1998-11-13 2001-12-04 Novo Nordisk A/S Tablet dispenser with rotating cover
GB9827200D0 (en) * 1998-12-11 1999-02-03 Glaxo Group Ltd Dry powder inhaler
US6196218B1 (en) 1999-02-24 2001-03-06 Ponwell Enterprises Ltd Piezo inhaler
US6601729B1 (en) * 1999-03-26 2003-08-05 Papp Enterprises, Llc Automated portable medication radial dispensing apparatus and method using a carrier tape
US6324428B1 (en) 1999-03-30 2001-11-27 Pacesetter, Inc. Implantable medical device having an improved electronic assembly for increasing packaging density and enhancing component protection
FI107126B (en) * 1999-04-23 2001-06-15 Orion Yhtymae Oyj Powder inhaler for combination medicine
US6158675A (en) 1999-09-22 2000-12-12 Anthony Manufacturing Corporation Residential Products Division Sprinkler spray head
GB9928265D0 (en) * 1999-12-01 2000-01-26 Innovata Biomed Ltd Inhaler
EP1235605B1 (en) * 1999-12-07 2005-06-01 Orion Corporation Multidose powder inhaler
GB0016478D0 (en) * 2000-07-05 2000-08-23 Innovata Biomed Ltd Valve
US6543443B1 (en) * 2000-07-12 2003-04-08 Aerogen, Inc. Methods and devices for nebulizing fluids
GB0102902D0 (en) * 2001-02-06 2001-03-21 Innovata Biomed Ltd Medicaments
US6523536B2 (en) * 2001-03-12 2003-02-25 Birdsong Medical Devices, Inc. Dual-canister inhaler having a spacer and easy to operate lever mechanism
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
GB0128148D0 (en) * 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly

Also Published As

Publication number Publication date
WO2000074754A2 (en) 2000-12-14
ES2241611T3 (en) 2005-11-01
AU777278B2 (en) 2004-10-07
NO20015910L (en) 2002-01-24
JP2003501158A (en) 2003-01-14
US20120199122A1 (en) 2012-08-09
NO20015910D0 (en) 2001-12-03
BR0011343A (en) 2002-03-12
IL146886A0 (en) 2002-08-14
NZ515557A (en) 2003-10-31
PT1183061E (en) 2005-08-31
WO2000074754A3 (en) 2001-06-28
CA2373278C (en) 2011-04-05
DE60019920D1 (en) 2005-06-09
EP1183061B2 (en) 2012-10-17
JP4540906B2 (en) 2010-09-08
DE60019920T2 (en) 2006-02-23
ATE294608T1 (en) 2005-05-15
US7207330B1 (en) 2007-04-24
EP1183061A2 (en) 2002-03-06
US20070039618A1 (en) 2007-02-22
AU5088800A (en) 2000-12-28
NZ524959A (en) 2004-12-24
MXPA01012533A (en) 2003-10-14
CA2725731A1 (en) 2000-12-14
EP1183061B1 (en) 2005-05-04
PL352615A1 (en) 2003-08-25

Similar Documents

Publication Publication Date Title
CA2373278A1 (en) Medicament delivery device with measuring chamber and dispensing cup
FI103952B (en) Device for administering powdered medical substances
KR101357508B1 (en) Device for dosing and dry nebulization
FI107126B (en) Powder inhaler for combination medicine
ZA200203764B (en) Inhaler.
BR0013700A (en) Dispensing device, dry powder inhaler, charger, methods of dispensing a material, administering a dry powder medicine and treating a patient with a respiratory disorder, and using salmeterol and / or fluticasone
CY1117867T1 (en) MEDICINAL DISPENSARY
BRPI0417155A (en) medicinal product comprising tiotropium in a moisture-proof container
TR200002005T2 (en) Device for inhalation of drugs used in medical practice in powder form.
WO2001064182A3 (en) Improvements in or relating to the delivery of oral drugs
ATE400313T1 (en) IMPROVED DRY POWDER INHALATION SYSTEM
US10857314B2 (en) Mouthpiece and inhaler
DE60013799D1 (en) powder inhaler

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20140605