CA2375962A1 - Heart assist devices, systems and methods - Google Patents

Heart assist devices, systems and methods Download PDF

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Publication number
CA2375962A1
CA2375962A1 CA002375962A CA2375962A CA2375962A1 CA 2375962 A1 CA2375962 A1 CA 2375962A1 CA 002375962 A CA002375962 A CA 002375962A CA 2375962 A CA2375962 A CA 2375962A CA 2375962 A1 CA2375962 A1 CA 2375962A1
Authority
CA
Canada
Prior art keywords
patient
aortic compression
aorta
compression means
cuff
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002375962A
Other languages
French (fr)
Other versions
CA2375962C (en
Inventor
William Suttle Peters
Peter Crispin Lawrence Marsh
Geoffrey Hamilton White
Frederick Paget Milsom
Hans Hansforth Henrichsen
Rolf Gunnar Unger
Colin Edward Sullivan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunshine Heart Co Pty Ltd
Original Assignee
Sunshine Heart Company Pty Ltd.
William Suttle Peters
Peter Crispin Lawrence Marsh
Geoffrey Hamilton White
Frederick Paget Milsom
Hans Hansforth Henrichsen
Rolf Gunnar Unger
Colin Edward Sullivan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunshine Heart Company Pty Ltd., William Suttle Peters, Peter Crispin Lawrence Marsh, Geoffrey Hamilton White, Frederick Paget Milsom, Hans Hansforth Henrichsen, Rolf Gunnar Unger, Colin Edward Sullivan filed Critical Sunshine Heart Company Pty Ltd.
Priority to CA2693289A priority Critical patent/CA2693289C/en
Publication of CA2375962A1 publication Critical patent/CA2375962A1/en
Application granted granted Critical
Publication of CA2375962C publication Critical patent/CA2375962C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/424—Details relating to driving for positive displacement blood pumps
    • A61M60/427—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
    • A61M60/435—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic with diastole or systole switching by valve means located between the blood pump and the hydraulic or pneumatic energy source
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/161—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel mechanically acting upon the outside of the patient's blood vessel structure, e.g. compressive structures placed around a vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/247—Positive displacement blood pumps
    • A61M60/253—Positive displacement blood pumps including a displacement member directly acting on the blood
    • A61M60/268—Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
    • A61M60/274—Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders the inlet and outlet being the same, e.g. para-aortic counter-pulsation blood pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/289—Devices for mechanical circulatory actuation assisting the residual heart function by means mechanically acting upon the patient's native heart or blood vessel structure, e.g. direct cardiac compression [DCC] devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/424—Details relating to driving for positive displacement blood pumps
    • A61M60/427—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
    • A61M60/432—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic with diastole or systole switching by stopping or reversing the blood pump operating at a much higher cyclical speed than the heart beat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/465—Details relating to driving for devices for mechanical circulatory actuation
    • A61M60/47—Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel
    • A61M60/473—Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel generated by an electromotor
    • A61M60/476—Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel generated by an electromotor with means converting the rotation into a translational movement of the displacement member
    • A61M60/478—Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel generated by an electromotor with means converting the rotation into a translational movement of the displacement member the axis of both movements being parallel, e.g. roller screw actuators or cylindrical cam transmissions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/465—Details relating to driving for devices for mechanical circulatory actuation
    • A61M60/47—Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel
    • A61M60/481—Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel generated by a solenoid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/30—Blood pressure

Abstract

A heart assist device (10) adapted for implantation into a patient (99). The device (10) includes an aortic compression means (60) adapted, when actuated, to compress an aorta (15) of a patient (99), a fluid reservoir (74) and a pump means (71) adapted to pump a fluid from the fluid reservoir (74) to the aortic compression means (60) so as to actuate the aortic compression means (60) at least partly in counterpulsation with the patient's heart. The fluid reservoir (74) is adapted to be wholly positioned within the chest cavity of the patient (99).

Claims (59)

1. A heart assist device adapted for implantation into a patient, the device including:
a) an aortic compression means is so shaped and dimensioned that it is adapted, when actuated, to compress the ascending aorta of a patient;
b) a fluid reservoir; and c) an electrically powered pump means adapted to pump a fluid from the fluid reservoir to the aortic compression means so as to actuate the aortic compression means at least partly in counterpulsation with the patient's heart, the fluid reservoir and the pump means are so shaped, dimensioned and interconnected that they are adapted to be wholly positioned within the right chest cavity of the patient.
2. A device as claimed in claim 1, wherein the fluid is a liquid.
3. A device as claimed in claim 2, wherein the liquid is water or saline.
4. A device as claimed in any one of the preceding claims, wherein the aortic compression means is curved along its length so as to substantially replicate the curve of the aorta adjacent to the aortic compression means.
5. A device as claimed in any one of the preceding claims, wherein the aortic compression means includes an elastic inflatable cuff adapted to at least partly encircle the aorta.
6. A device as claimed in claim 5, wherein the cuff is adapted to completely encircle the aorta.
7. A device as claimed in claim in claim 5 or 6, wherein the cuff is substantially C-shaped and includes two free ends that are adapted to overlap when the cuff is placed around the aorta.
8. A device as claimed in claim 7, wherein one of the free ends includes an elongated tongue adapted for suturing in an overlapping relationship to the other end to retain the device adjacent the aorta.
9. A device as claimed in any one of claims 5 to 8, wherein the cuff is a snug fit around the aorta of the patient.
10. A device as claimed in any one of the preceding claims, wherein the pump means and the fluid reservoir are provided in a fluid-filled substantially air-tight housing.
11. A device as claimed in claim 10, further including a pressure compliance means.
12. A device as claimed in claim 11, wherein the pressure compliance means forms part of the housing.
13. A device as claimed in claim 12, wherein the pressure compliance means is a substantially rigid portion of the housing downstream of the pump means, the portion being of sufficient rigidity so as to not deform inwardly during aortic compression nor deform outwardly in the absence of aortic compression.
14. A device as claimed in claim 12, wherein the pressure compliance means is a substantially flexible portion of the housing downstream of the pump means, the portion being of sufficient flexibility so as to deform inwardly during aortic compression and deform outwardly in the absence of aortic compression
15. A device as claimed in claim 14, wherein the flexible portion is adapted to be positioned in juxtaposition with a lung of the patient and deform outwardly to slightly compress the lung in the absence of aortic compression.
16. A device as claimed in any one of claims 5 to 15, wherein the cuff has a single inlet/outlet port.
17. A device as claimed in claim 16, wherein the port has a diffuser therein.
18. A device as claimed in claim 16 or 17, wherein the housing has an inlet/outlet port opening in fluid communication with the cuff inlet/outlet port.
19. A heart assist device adapted for implantation into a patient, the device including:
a) an aortic compression means which is curved along its length so as to substantially replicate the curve of the ascending aorta adjacent to the aortic compression means and is so shaped and dimensioned that it is adapted, when actuated, to compress the aorta of a patient;
b) a fluid reservoir; and c) pump means adapted to pump a fluid from the fluid reservoir to the aortic compression means so as to actuate the aortic compression means at least partly in counterpulsation with the patient's heart, the fluid reservoir and the pump means are so shaped, dimensioned and interconnected that they are adapted to be wholly positioned within the chest cavity of the patient.
20. A heart assist device adapted for implantation into a patient, the device including:
a) an aortic compression means which includes an inflatable cuff and is so shaped and dimensioned that it is adapted to encircle and, when actuated, compress the aorta of a patient, the cuff being substantially C-shaped and including two free ends that are adapted to overlap when the cuff is placed around the aorta ;
b) a fluid reservoir; and c) pump means adapted to pump a fluid from the fluid reservoir to the aortic compression means so as to actuate the aortic compression means at least partly in counterpulsation with the patient's heart, the fluid reservoir and the pump means are so shaped, dimensioned and interconnected that they are adapted to be wholly positioned within the chest cavity of the patient.
21. A heart assist device adapted for implantation into a patient, the device including:
a) an aortic compression means which includes an inflatable cuff and is so shaped and dimensioned that it is adapted to substantially encircle and, when actuated, compress the aorta of a patient, the cuff having two free ends, one of which includes an elongate tongue adapted for suturing or other connection in an overlapping relationship to the other end to retain the cuff in place around the aorta ;
b) a fluid reservoir; and c) pump means adapted to pump a fluid from the fluid reservoir to the aortic compression means so as to actuate the aortic compression means at least partly in counterpulsation with the patient's heart, the fluid reservoir and the pump means are so shaped, dimensioned and interconnected that they are adapted to be wholly positioned within the chest cavity of the patient.
22. A heart assist device adapted for implantation into a patient, the device including:
a) an aortic compression means which, when actuated, compress the aorta of a patient;
b) a fluid reservoir; and c) pump means adapted to pump a fluid from the fluid reservoir to the aortic compression means so as to actuate the aortic compression means at least partly in counterpulsation with the patient's heart, the fluid reservoir and the pump means are so shaped, dimensioned and interconnected that they are adapted to be wholly positioned within the chest cavity of the patient and the pump means and the fluid reservoir are provided in a fluid filled substantially air-tight housing.
23. A heart assist device adapted for implantation into a patient, the device including:
a) an aortic compression means adapted, when actuated, to compress the ascending aorta of a patient;
b) a liquid reservoir;
c) a pump means adapted to pump a liquid from the liquid reservoir to the aortic compression means so as to actuate the compression means, the liquid reservoir and the aortic compression means being adapted to be positioned in close juxtaposition with one another within the chest cavity of the patient, and d) means to sense the pressure in the liquid in the absence of aortic compression and alter the sensed pressure to a predetermined pressure.
24. A device as claimed in claim 23, wherein the distance between the liquid reservoir and the aortic compression means is no more than 6 cm.
25. A device as claimed in claim 19, 20, 21 or 22, further including a liquid conduit between the liquid reservoir and the aortic compression device which has minimum cross sectional area of at least 1 sq cm.
26. A device as claimed in any one of claims 23 to 25, further including a pressure compliance means.
27. A device as claimed in claim 26, wherein the liquid reservoir, the pump means and the pressure compliance means are provided in an air-tight housing.
28. A device as claimed in claim 27, wherein the housing is fluid-filled and the liquid reservoir is a portion of the interior of the housing.
29. A device as claimed in claim 27 or 28, wherein the pressure compliance means is a flexible portion of the housing adjacent the liquid reservoir.
30. A device as claimed in claim 29, wherein the flexible portion is adapted for positioning in juxtaposition with the lung of the patient.
31. A device as claimed in any one of the claims 19 to 30, wherein the pump means is adapted for active compression of the aortic compression means and active decompression of the aortic compression means.
32. A device as claimed in any one of claims 19 to 30, wherein the pump means is adapted for active compression of the aortic compression means and passive decompression of the aortic compression means.
33. A device as claimed in any one of claims 19 to 32, further including a liquid pressure adjustment means between the aortic compression means and the liquid reservoir and in fluid communication with the aortic compression means and the liquid reservoir.
34. A device as claimed in claim 33, wherein the liquid pressure adjustment means is a remote reservoir positioned near the patient's skin that is adapted for the receiving or the removal of liquid therein via a needle though the skin.
35. A device as claimed in claim 34, wherein the liquid pressure adjustment means is a remote reservoir positioned in the chest cavity that is adapted for the receiving or the removal of liquid therein via a transcutaneous tube connected thereto.
36. A device as claimed in claim 19, 20, 21 or 22, further including a means to sense the pressure in the liquid pressure adjustment means in the absence of aortic compression and alter the sensed pressure to a predetermined pressure.
37. An aortic compression means for use in a heart assist device, the aortic compression means including:
a) an elastic inflatable cuff adapted to be placed about the ascending aorta of a patient; and b) a flexible, substantially inelastic, sheath adapted to extend around the cuff and at least assist in retaining it in position on the aorta, wherein the aortic compression means is curved along its length so as to substantially replicate the curve of the ascending aorta adjacent to the aortic compression means.
38. An aortic compression means for use in a heart assist device, the aortic compression means including:
a) an elastic inflatable cuff adapted to be placed about the ascending aorta of a patient; and b) a flexible, substantially inelastic, sheath adapted to extend around the cuff and at least assist in retaining it in position on the aorta, wherein the cuff is substantially C-shaped and includes two free ends that are adapted to overlap when the cuff is placed around the aorta.
39. An aortic compression means for use in a heart assist device, the aortic compression means including:
a) an elastic inflatable cuff adapted to be placed about the ascending aorta of a patient; and b) a flexible, substantially inelastic, sheath adapted to extend around the cuff and at least assist in retaining it in position on the aorta, wherein the cuff is substantially C-shaped and includes two free ends, one of the free ends includes an elongated tongue adapted for suturing or otherwise connected in an overlapping relationship to the other end to retain the device adjacent the aorta.
40. A device as claimed in claim 37, 38 or 39, wherein the cuff is adapted to at least partially encircle the aorta.
41. A device as claimed in claim 40, wherein the cuff is adapted to completely encircle the aorta of the patient.
42. A device as claimed in claim 37 or 39, wherein the cuff is substantially C-shaped and includes two free ends that are adapted to overlap when the cuff is placed around the aorta.
43. A device as claimed in claim 37 or 38, wherein one of the free ends includes an elongated tongue adapted for suturing in an overlapping relationship to the other end to retain the device adjacent the aorta.
44. A device as claimed in any one of claims 37 to 43, wherein the cuff is a snug fit around the aorta of the patient.
45. A means as claimed in any one of claims 37 to 44, wherein the sheath is a snug fit around the cuff.
46. A device as claimed in any one of claims 37 to 45, wherein the cuff has a single inlet/outlet port.
47. A device as claimed in claim 46, wherein the sheath has an opening complimentary to the cuff inlet/outlet port.
48. A device as claimed in claim 37 to 47, wherein the cuff is inflatable to an enlarged pressurised configuration to compressing the aorta and relaxes to a static configuration to relax the aorta.
49. A heart assist device including:

a) an aortic compression means adapted by its shape and dimensions to be placed around the ascending aorta of a patient; and b) mechanical or electrical actuation means to periodically actuate the aortic compression means in at least partial counterpulsation with the heart, wherein the aortic compression means and the actuation means are placed wholly within the right chest cavity of the patient.
50. A device as claimed in claim 49, wherein the aortic compression means and the actuation means are adapted to be connected in close juxtaposition within the right chest cavity of a patient.
51. A device as claimed in claim 49 or 50, wherein the aortic compression means is inflatable to compress the aorta and the actuation means includes a pump means adapted to pump fluid into the aortic compression means to inflate same.
52. A device as claimed in claim 51, wherein the actuation means further includes a fluid reservoir and a pressure compensation means.
53. A device as claimed in claim 52, wherein the pump means, fluid reservoir and the pressure compensation means are contained in a fluid-filled air-tight housing.
54. A device as claimed in any one of claims 49 to 53, wherein the pump means is an impeller adapted to drive fluid from the fluid reservoir and the aortic compression means.
55. A device as claimed in any one of claims 51 to 53, wherein the pump means is a fluid-filled sac adapted to be compressed to drive fluid from the sac to the aortic compression means.
56. A device as claimed in any one of claims 51 to 55, wherein the aortic compression means is an inflatable cuff adapted for positioning about the aorta of the patient.
57. A heart assist device adapted for implantation wholly into the chest cavity of a patient, the device including:
a) an aortic compression means adapted, when actuated, to compress an aorta of a patient;
b) a housing with an exterior surface;
c) a fluid reservoir in the housing, the fluid reservoir having a flexible exterior surface forming part of the housing exterior surface; and d) a pump means adapted to pump a fluid from the fluid reservoir to the aortic compression means so as to actuate the aortic compression means at least partly in counterpulsation with the patient's heart, wherein the fluid reservoir flexible exterior surface is adapted to contract during aortic compression and expand in the absence of aortic compression and is further adapted to be positioned substantially adjacent a lung in the patient's chest cavity.
58. A device as claimed in claim 57, wherein the bodily cavity is the thoracic cavity and the organ is the lung.
59. A heart assist device as claimed in any one of claims 1 to 36, or 49 to 58 or an aortic compression device as claimed in any one of claims 37 to 48 when placed in a human or other animal.
CA2375962A 1999-06-10 2000-06-09 Heart assist devices, systems and methods Expired - Fee Related CA2375962C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2693289A CA2693289C (en) 1999-06-10 2000-06-09 Heart assist devices, systems and methods

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPQ0904A AUPQ090499A0 (en) 1999-06-10 1999-06-10 Heart assist device and system
AUPQ0904 1999-06-10
PCT/AU2000/000654 WO2000076288A2 (en) 1999-06-10 2000-06-09 Heart assist devices, systems and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2693289A Division CA2693289C (en) 1999-06-10 2000-06-09 Heart assist devices, systems and methods

Publications (2)

Publication Number Publication Date
CA2375962A1 true CA2375962A1 (en) 2000-12-21
CA2375962C CA2375962C (en) 2010-04-20

Family

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CA2375962A Expired - Fee Related CA2375962C (en) 1999-06-10 2000-06-09 Heart assist devices, systems and methods
CA2693289A Expired - Fee Related CA2693289C (en) 1999-06-10 2000-06-09 Heart assist devices, systems and methods

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Application Number Title Priority Date Filing Date
CA2693289A Expired - Fee Related CA2693289C (en) 1999-06-10 2000-06-09 Heart assist devices, systems and methods

Country Status (11)

Country Link
US (4) US6808484B1 (en)
EP (2) EP2263713A3 (en)
JP (2) JP4267232B2 (en)
CN (1) CN1355715A (en)
AU (1) AUPQ090499A0 (en)
BR (1) BR0011464A (en)
CA (2) CA2375962C (en)
DK (1) DK1185319T3 (en)
ES (1) ES2407680T3 (en)
MX (1) MXPA01012635A (en)
WO (1) WO2000076288A2 (en)

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