CA2384822A1 - System and method for tomographic imaging of dynamic properties of a scattering medium - Google Patents
System and method for tomographic imaging of dynamic properties of a scattering medium Download PDFInfo
- Publication number
- CA2384822A1 CA2384822A1 CA002384822A CA2384822A CA2384822A1 CA 2384822 A1 CA2384822 A1 CA 2384822A1 CA 002384822 A CA002384822 A CA 002384822A CA 2384822 A CA2384822 A CA 2384822A CA 2384822 A1 CA2384822 A1 CA 2384822A1
- Authority
- CA
- Canada
- Prior art keywords
- medium
- optical energy
- tomographic imaging
- dynamic properties
- scattering medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
Landscapes
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
A system and method for the detection and three dimensional imaging of absorption and scattering properties of a medium such as human tissue is described. According to one embodiment of the invention, the system directs optical energy toward a turbid medium from at least one source and detects optical energy emerging from the turbid medium at a plurality of locations uisng at least one detector (106). The optical energy emerging from the medium (102) and entering the detector (106) originates from the source (101) is scattered by the medium (102). The system then generates an image representing interior structure of the turbid medium based on the detected optical energy emerging from the medium (102). Generating the image includes a time-series analysis.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15392699P | 1999-09-14 | 1999-09-14 | |
US60/153,926 | 1999-09-14 | ||
US15409999P | 1999-09-15 | 1999-09-15 | |
US60/154,099 | 1999-09-15 | ||
PCT/US2000/025155 WO2001020306A1 (en) | 1999-09-14 | 2000-09-14 | System and method for tomographic imaging of dynamic properties of a scattering medium |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2384822A1 true CA2384822A1 (en) | 2001-03-22 |
CA2384822C CA2384822C (en) | 2007-01-02 |
Family
ID=26850998
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002384822A Expired - Fee Related CA2384822C (en) | 1999-09-14 | 2000-09-14 | System and method for tomographic imaging of dynamic properties of a scattering medium |
CA2384813A Expired - Fee Related CA2384813C (en) | 1999-09-14 | 2000-09-14 | Method and system for imaging the dynamics of scattering medium |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2384813A Expired - Fee Related CA2384813C (en) | 1999-09-14 | 2000-09-14 | Method and system for imaging the dynamics of scattering medium |
Country Status (6)
Country | Link |
---|---|
US (1) | USRE41949E1 (en) |
EP (2) | EP1221034B1 (en) |
JP (3) | JP2003509687A (en) |
AU (2) | AU7579500A (en) |
CA (2) | CA2384822C (en) |
WO (2) | WO2001020306A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2319397B1 (en) * | 2001-06-22 | 2013-06-05 | Nellcor Puritan Bennett Ireland | Wavelet-based analysis of pulse oximetry signals |
WO2003012736A2 (en) * | 2001-08-02 | 2003-02-13 | The Research Foundation Of State University Of Ne W York | Method and system for enhancing solutions to a system of linear equations |
US6662128B2 (en) | 2002-01-18 | 2003-12-09 | The Research Foundation Of State University Of New York | Normalized-constraint algorithm for minimizing inter-parameter crosstalk in imaging of scattering media |
CA2481518A1 (en) | 2002-04-06 | 2003-10-23 | Randall L. Barbour | A system and method for quantifying the dynamic response of a target system |
WO2003088133A1 (en) | 2002-04-06 | 2003-10-23 | Barbour Randall L | Modification of the normalized difference method for real-time optical tomography |
WO2005006962A2 (en) | 2003-07-18 | 2005-01-27 | Nirx Medical Technologies, L.L.C. | Image enhancement by spatial linear deconvolution |
JP2007522133A (en) * | 2004-01-23 | 2007-08-09 | エスアールアイ インターナショナル | Optical vascular function imaging system and cancerous tumor detection and diagnosis method |
US7471975B2 (en) * | 2004-09-22 | 2008-12-30 | The Research Foundation Of State University Of New York | Optical tensor imaging |
DE102005039184B4 (en) | 2005-08-18 | 2011-05-19 | Siemens Ag | Method for evaluating a cinematographic image series of the heart, magnetic resonance tomography apparatus and computer program |
EP1954178B1 (en) * | 2005-11-23 | 2018-08-22 | Koninklijke Philips N.V. | A method and device for imaging an interior of a turbid medium |
CN101404925A (en) * | 2006-03-17 | 2009-04-08 | 皇家飞利浦电子股份有限公司 | A device for imaging a turbid medium |
KR101041295B1 (en) * | 2006-03-31 | 2011-06-14 | 가부시키가이샤 시마즈세이사쿠쇼 | Mammography system |
EP2120687A1 (en) * | 2006-12-19 | 2009-11-25 | Koninklijke Philips Electronics N.V. | Imaging of a turbid medium |
CA2781393C (en) | 2009-11-19 | 2017-08-08 | Modulated Imaging, Inc. | Method and apparatus for analysis of turbid media via single-element detection using structured illumination |
WO2012065140A2 (en) | 2010-11-11 | 2012-05-18 | The Trustees Of Columbia University In The City Of New York | Dynamic optical tomographic imaging devices methods and systems |
BR112015010459B1 (en) | 2012-11-07 | 2021-01-26 | Modulated Imaging, Inc. | method for measuring a cloudy sample |
USD763938S1 (en) | 2014-04-02 | 2016-08-16 | Cephalogics, LLC | Optical sensor array |
USD763939S1 (en) | 2014-04-02 | 2016-08-16 | Cephalogics, LLC | Optical sensor array liner with optical sensor array pad |
US9599697B2 (en) | 2014-04-15 | 2017-03-21 | The Johns Hopkins University | Non-contact fiber optic localization and tracking system |
Family Cites Families (29)
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US4810875A (en) * | 1987-02-02 | 1989-03-07 | Wyatt Technology Corporation | Method and apparatus for examining the interior of semi-opaque objects |
US5137355A (en) * | 1988-06-08 | 1992-08-11 | The Research Foundation Of State University Of New York | Method of imaging a random medium |
US5353799A (en) * | 1991-01-22 | 1994-10-11 | Non Invasive Technology, Inc. | Examination of subjects using photon migration with high directionality techniques |
US5365066A (en) * | 1989-01-19 | 1994-11-15 | Futrex, Inc. | Low cost means for increasing measurement sensitivity in LED/IRED near-infrared instruments |
US5386819A (en) * | 1990-03-29 | 1995-02-07 | Olympus Optical Co., Ltd. | Method and apparatus for inhibiting a scattered component in a light having passed through an examined object |
JPH04249746A (en) * | 1990-12-31 | 1992-09-04 | Shimadzu Corp | Reconstructing method of tomographic image |
JP3217386B2 (en) * | 1991-04-24 | 2001-10-09 | オリンパス光学工業株式会社 | Diagnostic system |
US6485413B1 (en) * | 1991-04-29 | 2002-11-26 | The General Hospital Corporation | Methods and apparatus for forward-directed optical scanning instruments |
WO1994005209A1 (en) * | 1992-08-31 | 1994-03-17 | Hitachi, Ltd. | Optical ct apparatus |
US5762609A (en) * | 1992-09-14 | 1998-06-09 | Sextant Medical Corporation | Device and method for analysis of surgical tissue interventions |
US5676141A (en) * | 1993-03-31 | 1997-10-14 | Nellcor Puritan Bennett Incorporated | Electronic processor for pulse oximeters |
JP3234353B2 (en) * | 1993-06-15 | 2001-12-04 | 富士写真フイルム株式会社 | Tomographic information reader |
US5820558A (en) * | 1994-12-02 | 1998-10-13 | Non-Invasive Technology, Inc. | Optical techniques for examination of biological tissue |
JP3433508B2 (en) * | 1993-12-01 | 2003-08-04 | 浜松ホトニクス株式会社 | Scattering absorber measurement method and scattering absorber measuring device |
US5803909A (en) * | 1994-10-06 | 1998-09-08 | Hitachi, Ltd. | Optical system for measuring metabolism in a body and imaging method |
US5625458A (en) * | 1994-11-10 | 1997-04-29 | Research Foundation Of City College Of New York | Method and system for imaging objects in turbid media using diffusive fermat photons |
DE69627477T2 (en) * | 1995-01-03 | 2004-03-18 | Non-Invasive Technology, Inc. | OPTICAL COUPLING DEVICE FOR IN-VIVO EXAMINATION OF BIOLOGICAL TISSUES |
MX9801351A (en) * | 1995-08-24 | 1998-07-31 | Purdue Research Foundation | Fluorescence lifetime-based imaging and spectroscopy in tissues and other random media. |
DE19681107B4 (en) * | 1995-11-17 | 2006-01-26 | Hitachi, Ltd. | Instrument for optical measurement in a living body |
US6108576A (en) * | 1996-03-18 | 2000-08-22 | The Research Foundation Of City College Of New York | Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media |
EP0897282A2 (en) * | 1996-12-03 | 1999-02-24 | Koninklijke Philips Electronics N.V. | Method and apparatus for imaging an interior of a turbid medium |
US6091983A (en) * | 1997-02-07 | 2000-07-18 | Alfano; Robert R. | Imaging of objects in turbid media based upon the preservation of polarized luminescence emitted from contrast agents |
US5994690A (en) * | 1997-03-17 | 1999-11-30 | Kulkarni; Manish D. | Image enhancement in optical coherence tomography using deconvolution |
US6081322A (en) * | 1997-10-16 | 2000-06-27 | Research Foundation Of State Of New York | NIR clinical opti-scan system |
WO1999026526A1 (en) * | 1997-11-22 | 1999-06-03 | Koninklijke Philips Electronics N.V. | Method of localizing an object in a turbid medium |
EP1054619B1 (en) * | 1998-02-11 | 2007-11-21 | Non-Invasive Technology, Inc. | Imaging and characterization of brain tissue |
AU763861B2 (en) * | 1998-05-19 | 2003-07-31 | Spectrx, Inc. | Apparatus and method for determining tissue characteristics |
US6377842B1 (en) * | 1998-09-22 | 2002-04-23 | Aurora Optics, Inc. | Method for quantitative measurement of fluorescent and phosphorescent drugs within tissue utilizing a fiber optic probe |
ATE268901T1 (en) * | 1999-01-29 | 2004-06-15 | June Iris Medford | OPTICAL COHERENCE MICROSCOPE AND METHOD FOR RAPID 3D IN-VIVO VISUALIZATION OF BIOLOGICAL FUNCTIONS |
-
2000
- 2000-09-14 JP JP2001523841A patent/JP2003509687A/en active Pending
- 2000-09-14 US US11/525,188 patent/USRE41949E1/en not_active Expired - Lifetime
- 2000-09-14 WO PCT/US2000/025155 patent/WO2001020306A1/en active Application Filing
- 2000-09-14 AU AU75795/00A patent/AU7579500A/en not_active Abandoned
- 2000-09-14 AU AU75793/00A patent/AU7579300A/en not_active Abandoned
- 2000-09-14 JP JP2001523840A patent/JP5047432B2/en not_active Expired - Fee Related
- 2000-09-14 WO PCT/US2000/025136 patent/WO2001020305A1/en active Application Filing
- 2000-09-14 CA CA002384822A patent/CA2384822C/en not_active Expired - Fee Related
- 2000-09-14 CA CA2384813A patent/CA2384813C/en not_active Expired - Fee Related
- 2000-09-14 EP EP00964994.8A patent/EP1221034B1/en not_active Expired - Lifetime
- 2000-09-14 EP EP00964997A patent/EP1221035B1/en not_active Expired - Lifetime
-
2011
- 2011-10-25 JP JP2011234271A patent/JP2012053053A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
USRE41949E1 (en) | 2010-11-23 |
WO2001020305A9 (en) | 2002-09-26 |
CA2384822C (en) | 2007-01-02 |
EP1221034A4 (en) | 2009-06-24 |
WO2001020306A1 (en) | 2001-03-22 |
JP5047432B2 (en) | 2012-10-10 |
CA2384813A1 (en) | 2001-03-22 |
JP2003527883A (en) | 2003-09-24 |
WO2001020306A9 (en) | 2002-09-26 |
JP2003509687A (en) | 2003-03-11 |
JP2012053053A (en) | 2012-03-15 |
WO2001020305A1 (en) | 2001-03-22 |
EP1221035B1 (en) | 2012-05-23 |
EP1221034B1 (en) | 2013-05-22 |
EP1221035A4 (en) | 2009-07-01 |
AU7579300A (en) | 2001-04-17 |
EP1221035A1 (en) | 2002-07-10 |
CA2384813C (en) | 2014-01-21 |
EP1221034A1 (en) | 2002-07-10 |
AU7579500A (en) | 2001-04-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20160914 |