CA2386215A1 - Method for treatment of chronic venous insufficiencies using an extract of red vine leaves - Google Patents

Method for treatment of chronic venous insufficiencies using an extract of red vine leaves Download PDF

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Publication number
CA2386215A1
CA2386215A1 CA002386215A CA2386215A CA2386215A1 CA 2386215 A1 CA2386215 A1 CA 2386215A1 CA 002386215 A CA002386215 A CA 002386215A CA 2386215 A CA2386215 A CA 2386215A CA 2386215 A1 CA2386215 A1 CA 2386215A1
Authority
CA
Canada
Prior art keywords
extract
treatment
chronic venous
vine leaves
red vine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002386215A
Other languages
French (fr)
Other versions
CA2386215C (en
Inventor
Anke Esperester
Hans W. Frey
Jean-Michel Vix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22577208&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2386215(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2386215A1 publication Critical patent/CA2386215A1/en
Application granted granted Critical
Publication of CA2386215C publication Critical patent/CA2386215C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention relates to a dietary supplement consisting of an aqueous extract of red vine leaves and an acceptable carrier which prevents and reduces the discomfort relating to mild-to-moderate chronic venous insufficiency of the legs.
CA002386215A 1999-10-20 2000-10-19 Method for treatment of chronic venous insufficiencies using an extract of red vine leaves Expired - Lifetime CA2386215C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16051899P 1999-10-20 1999-10-20
US60/160,518 1999-10-20
PCT/EP2000/010292 WO2001028363A1 (en) 1999-10-20 2000-10-19 Method for treatment of chronic venous insufficiencies using an extract of red vine leaves

Publications (2)

Publication Number Publication Date
CA2386215A1 true CA2386215A1 (en) 2001-04-26
CA2386215C CA2386215C (en) 2009-07-21

Family

ID=22577208

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002386215A Expired - Lifetime CA2386215C (en) 1999-10-20 2000-10-19 Method for treatment of chronic venous insufficiencies using an extract of red vine leaves

Country Status (20)

Country Link
US (4) US6485727B1 (en)
EP (4) EP2286676A1 (en)
JP (2) JP2001122791A (en)
CN (1) CN1197481C (en)
AR (2) AR031533A1 (en)
AT (2) ATE323427T1 (en)
AU (1) AU1273701A (en)
BR (1) BRPI0014874B8 (en)
CA (1) CA2386215C (en)
CO (1) CO5251468A1 (en)
CY (1) CY1105049T1 (en)
DE (2) DE60027481T2 (en)
DK (2) DK1300084T3 (en)
ES (2) ES2193112T3 (en)
HK (1) HK1048580B (en)
MX (1) MXPA02003595A (en)
PE (1) PE20010677A1 (en)
PT (2) PT1225810E (en)
SA (1) SA00210550B1 (en)
WO (1) WO2001028363A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001122791A (en) 1999-10-20 2001-05-08 Boehringer Ingelheim Internatl Gmbh Meal enhancer comprising aqueous extract of red vine leaf for alleviation and prophylaxis of chronic venous insufficiency in lower extremity
JP2003342184A (en) * 2002-05-31 2003-12-03 Ichimaru Pharcos Co Ltd Hyaluronidase activity inhibitor and cosmetic composition
US20040151794A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Method of improvement of blood circulation
EP1435242A1 (en) * 2002-12-31 2004-07-07 Pharmaton S.A. Method of improvement of blood circulation
US20040151769A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Film coated tablet containing an extract of red vine leaves
JP4989071B2 (en) * 2002-12-31 2012-08-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Film-coated tablets containing red grape leaf extract
EP1550450A1 (en) * 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a blood circulating-improving agent for the treatment of chronic venous insufficiencies
EP1550451A1 (en) * 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a diuretic for the treatment of chronic venous insufficiencies
EP1550452A1 (en) * 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a antthrombotic agent for the treatment of chronic venous insufficiencies
BRPI0507895A (en) * 2004-02-19 2007-07-24 Boehringer Ingelheim Int composition for the treatment of chronic venous insufficiency, comprising an extract of red vine leaves and an anti-inflammatory agent
US20060293258A1 (en) * 2005-06-23 2006-12-28 Peter Rohdewald Method and composition to treat skin ulcers
WO2007049796A2 (en) * 2005-10-26 2007-05-03 Kao Corporation Resveratrol and/or grape leaf extract as i. a. endurance improver, anti-aging agent, muscle strength improver
UA104994C2 (en) * 2007-08-31 2014-04-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх Sprayable composition containing red vine leaf extract
DE102008012908A1 (en) * 2008-03-06 2009-09-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the anti-inflammatory and anti-edematous protection of explanted biological material up to its transplantation in patients
DE102008012909A1 (en) * 2008-03-06 2009-09-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Use of flavonoid compounds for the prophylaxis and therapy of ischemic or inflammatory cardiovascular diseases
MX343308B (en) * 2010-05-28 2016-11-01 Boehringer Ingelheim Int Gmbh * Method for producing an enriched extract from vitis vinifera l. leaves.
EP2575844B1 (en) * 2010-05-28 2016-11-23 Finzelberg GmbH & Co. KG Method for producing an enriched extract from vine plants
JP6321908B2 (en) * 2013-02-19 2018-05-09 エスエス製薬株式会社 Oral composition for swelling treatment
DE202014006415U1 (en) * 2014-08-12 2015-11-13 Boehringer Ingelheim International Gmbh Water-soluble granules for the preparation of a drink solution

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL278161A (en) 1961-05-13
FR2276059A1 (en) 1974-06-25 1976-01-23 Agronomique Inst Nat Rech Pigments with vitamin P activity - aq. extn. from vine leaves in presence of sulphur dioxide
JPS55111791A (en) 1979-02-22 1980-08-28 Japan Synthetic Rubber Co Ltd Antitumor substance
FR2556969B1 (en) 1983-12-27 1986-04-25 Oreal COSMETIC OR PHARMACEUTICAL COMPOSITION BASED ON PLANT EXTRACTS HAVING ACTION ON HAIR FRAGILITY
GB8524001D0 (en) 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
CH680854A5 (en) 1990-05-09 1992-11-30 Nestle Sa
FR2715582B1 (en) * 1994-02-02 1996-03-15 Centre Nat Rech Scient Microcapsules with crosslinked flavonoid walls and compositions containing them.
IT1270999B (en) 1994-07-26 1997-05-26 Indena Spa FORMULATIONS BASED ON CUMARINES AND THEIR USE IN THE PHARMACEUTICAL AND COSMETIC FIELD
FR2726273B1 (en) 1994-10-26 1996-12-06 Adir NOVEL DIOSMETINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CH690817A5 (en) 1996-09-03 2001-01-31 Flachsmann Ag Emil A method for preparing a stable, homogeneous, free from secondary products or nearly free extract.
US20020165270A1 (en) 1997-05-13 2002-11-07 Jose Remacle Use of a pharmaceutical composition for treating and/or preventing ischemia
WO1999009988A1 (en) 1997-08-27 1999-03-04 Hexal Ag New pharmaceutical compositions of meloxicam with improved solubility and bioavailability
IT1296920B1 (en) 1997-12-04 1999-08-03 Indena Spa USE OF VITIS VINIFERA EXTRACT COMPLEXES WITH PHOSPHOLIPIDS AS ANTI-ATHEROSCLEROTIC AGENTS
US6342255B1 (en) 1998-09-15 2002-01-29 Codex V S.R.L. Topical pharmaceutical compositions useful for the treatment of cutaneous of circulatory pathologies on inflammatory, immune, proliferative of degenerative basis
US6210680B1 (en) 1999-06-11 2001-04-03 Univera Pharmaceuticals, Inc. Method for the prevention and treatment of chronic venous insufficiency
EP1214084B1 (en) 1999-09-10 2005-04-06 Ceteris Holding B.V.-Amsterdam (Olanda) - Succursale di Lugano An anti-oxidant preparation based on plant extracts for the treatment of circulation and adiposity problems
JP2001122791A (en) 1999-10-20 2001-05-08 Boehringer Ingelheim Internatl Gmbh Meal enhancer comprising aqueous extract of red vine leaf for alleviation and prophylaxis of chronic venous insufficiency in lower extremity
FR2804319B1 (en) * 2000-01-28 2002-10-25 Clarins Lab SLIMMING COSMETIC COMPOSITION COMPRISING AS AN ACTIVE AGENT A PLANT EXTRACT CONTAINING ANP
AU5574101A (en) 2000-04-28 2001-11-12 Univ Emory Decellularized vascular prostheses
ES2261416T3 (en) * 2000-05-25 2006-11-16 Boehringer Ingelheim International Gmbh METHOD FOR IMPROVING CELLULAR PROTECTION INCLUDING A LIPOFILIC ANTIOXIDANT AND A HYDROPHYLIC ANTIOXIDANT.
BRPI0106382B1 (en) 2001-03-13 2017-07-11 Universidade Do Estado Do Rio De Janeiro - Uerj PROCESS FOR OBTAINING DECOCTS FROM VITIS LABRUSCA AND VITIS VINIFERA CASTS, PROCESS FOR OBTAINING THE HYDRO-ALCOHOLIC EXTRACT, PROCESS FOR OBTAINING THE HYDRO-ALCOHOLIC EXTRACT
US20020192834A1 (en) 2001-03-23 2002-12-19 Sand Bruce J. Analysis of caffeine
US8936588B2 (en) 2001-09-21 2015-01-20 Fred Herz Patents, LLC Device and method for prevention and treatment of deep venous thrombosis
WO2003035092A1 (en) 2001-10-26 2003-05-01 Angiolab Inc. Composition containing horse chestnut extract for anti-angiogenic and matrix metalloproteinase inhibitory activity
US6579543B1 (en) 2002-02-22 2003-06-17 Jackie H. McClung Composition for topical application to skin
DE20209650U1 (en) 2002-06-21 2002-09-12 Sterken Brigitte Vein Active Balm
US20040151794A1 (en) 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Method of improvement of blood circulation
US20040151769A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Film coated tablet containing an extract of red vine leaves
US20040146539A1 (en) 2003-01-24 2004-07-29 Gupta Shyam K. Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits
US20040223962A1 (en) 2003-05-07 2004-11-11 Riordan Neil H. Method and composition for preventing or reducing edema, deep vein thrombosis and/or pulmonary embolism
EP1550451A1 (en) 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a diuretic for the treatment of chronic venous insufficiencies
EP1550452A1 (en) 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a antthrombotic agent for the treatment of chronic venous insufficiencies
EP1550450A1 (en) 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a blood circulating-improving agent for the treatment of chronic venous insufficiencies
BRPI0507895A (en) 2004-02-19 2007-07-24 Boehringer Ingelheim Int composition for the treatment of chronic venous insufficiency, comprising an extract of red vine leaves and an anti-inflammatory agent

Also Published As

Publication number Publication date
MXPA02003595A (en) 2002-10-23
EP1300084B1 (en) 2006-04-19
EP2286676A1 (en) 2011-02-23
EP1300084A3 (en) 2003-09-03
DE60001857T2 (en) 2003-11-27
ATE323427T1 (en) 2006-05-15
DK1225810T3 (en) 2003-07-07
CN1197481C (en) 2005-04-20
DE60027481D1 (en) 2006-05-24
PT1225810E (en) 2003-08-29
JP2003511476A (en) 2003-03-25
CN1382022A (en) 2002-11-27
EP1300084A2 (en) 2003-04-09
HK1048580B (en) 2005-08-12
PE20010677A1 (en) 2001-07-06
AR061707A2 (en) 2008-09-17
AR031533A1 (en) 2003-09-24
BR0014874A (en) 2002-06-11
EP1225810B1 (en) 2003-03-26
HK1048580A1 (en) 2003-04-11
US20060068043A1 (en) 2006-03-30
US6991816B2 (en) 2006-01-31
PT1300084E (en) 2006-06-30
CA2386215C (en) 2009-07-21
US20040062824A1 (en) 2004-04-01
SA00210550B1 (en) 2006-05-06
EP1225810A1 (en) 2002-07-31
DK1300084T3 (en) 2006-05-22
JP2001122791A (en) 2001-05-08
EP1649761A1 (en) 2006-04-26
AU1273701A (en) 2001-04-30
US7270838B2 (en) 2007-09-18
DE60027481T2 (en) 2006-08-31
BRPI0014874B8 (en) 2021-05-25
WO2001028363A1 (en) 2001-04-26
BRPI0014874B1 (en) 2018-02-27
DE60001857D1 (en) 2003-04-30
CY1105049T1 (en) 2010-03-03
US6485727B1 (en) 2002-11-26
ES2261796T3 (en) 2006-11-16
CO5251468A1 (en) 2003-02-28
ATE235167T1 (en) 2003-04-15
US20030031739A1 (en) 2003-02-13
ES2193112T3 (en) 2003-11-01

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20201019

MKEX Expiry

Effective date: 20201019